Shawn C. Owen - Publications

Affiliations: 
2009-2013 Chemistry University of Toronto, Toronto, ON, Canada 

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Arlotta K, San BH, Mu HH, Yu SM, Owen S. Localization of Therapeutic Fab-CHP Conjugates to Sites of Denatured Collagen for the Treatment of Rheumatoid Arthritis. Bioconjugate Chemistry. PMID 32609496 DOI: 10.1021/Acs.Bioconjchem.0C00324  0.307
2019 Radford DC, Yang J, Doan MC, Li L, Dixon AS, Owen SC, Kopeček J. Multivalent HER2-binding polymer conjugates facilitate rapid endocytosis and enhance intracellular drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31899273 DOI: 10.1016/J.Jconrel.2019.12.049  0.423
2019 Nervig CS, Owen SC. Affinity-bound antibody-drug conjugates. Nature Biomedical Engineering. 3: 850-851. PMID 31686000 DOI: 10.1038/S41551-019-0478-0  0.404
2019 Arlotta KJ, Owen SC. Antibody and antibody derivatives as cancer therapeutics. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1556. PMID 30968595 DOI: 10.1002/Wnan.1556  0.392
2019 Quinn C, Owen S, Arlotta K. Native Quantitative Determination of Antibody-Drug Conjugate Affinity and Stability Biophysical Journal. 116: 193a. DOI: 10.1016/J.Bpj.2018.11.1067  0.399
2018 Arlotta KJ, Gandhi AV, Chen HN, Nervig CS, Carpenter JF, Owen SC. In-Depth Comparison of Lysine-Based Antibody-Drug Conjugates Prepared on Solid Support Versus in Solution. Antibodies (Basel, Switzerland). 7. PMID 31544859 DOI: 10.3390/Antib7010006  0.399
2018 Gandhi AV, Arlotta KJ, Chen HN, Owen SC, Carpenter JF. Biophysical Properties and Heating-Induced Aggregation of Lysine Conjugated Antibody-Drug Conjugates. Journal of Pharmaceutical Sciences. PMID 29626535 DOI: 10.1016/J.Xphs.2018.03.022  0.411
2017 Taurin S, Almomen AA, Pollak T, Kim SJ, Maxwell J, Peterson CM, Owen SC, Janát-Amsbury MM. Thermosensitive hydrogels a versatile concept adapted to vaginal drug delivery. Journal of Drug Targeting. 1-50. PMID 29096548 DOI: 10.1080/1061186X.2017.1400551  0.373
2017 Dixon AS, Kim SJ, Baumgartner BK, Krippner S, Owen SC. A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays. Scientific Reports. 7: 8186. PMID 28811487 DOI: 10.1038/S41598-017-07569-Y  0.317
2015 McCombs JR, Owen SC. Antibody drug conjugates: design and selection of linker, payload and conjugation chemistry. The Aaps Journal. 17: 339-51. PMID 25604608 DOI: 10.1208/S12248-014-9710-8  0.396
2015 Fisher SA, Anandakumaran PN, Owen SC, Shoichet MS. Tuning the Microenvironment: Click-Crosslinked Hyaluronic Acid-Based Hydrogels Provide a Platform for Studying Breast Cancer Cell Invasion Advanced Functional Materials. 25: 7163-7172. DOI: 10.1002/Adfm.201502778  0.536
2014 Owen SC, Doak AK, Ganesh AN, Nedyalkova L, McLaughlin CK, Shoichet BK, Shoichet MS. Colloidal drug formulations can explain "bell-shaped" concentration-response curves. Acs Chemical Biology. 9: 777-84. PMID 24397822 DOI: 10.1021/Cb4007584  0.64
2014 Logie J, Owen SC, McLaughlin CK, Shoichet MS. PEG-graft density controls polymeric nanoparticle micelle stability Chemistry of Materials. 26: 2847-2855. DOI: 10.1021/Cm500448X  0.67
2014 Tam RY, Owen SC, Shoichet MS. ECM-Inspired Chemical Cues: Biomimetic Molecules and Techniques of Immobilization Bio-Inspired Materials For Biomedical Engineering. 5-24. DOI: 10.1002/9781118843499.ch1  0.41
2013 Chan DPY, Deleavey GF, Owen SC, Damha MJ, Shoichet MS. Click conjugated polymeric immuno-nanoparticles for targeted siRNA and antisense oligonucleotide delivery Biomaterials. 34: 8408-8415. PMID 23932248 DOI: 10.1016/J.Biomaterials.2013.07.019  0.578
2013 Owen SC, Patel N, Logie J, Pan G, Persson H, Moffat J, Sidhu SS, Shoichet MS. Targeting HER2+ breast cancer cells: lysosomal accumulation of anti-HER2 antibodies is influenced by antibody binding site and conjugation to polymeric nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 395-404. PMID 23880472 DOI: 10.1016/J.Jconrel.2013.07.011  0.677
2013 Owen SC, Fisher SA, Tam RY, Nimmo CM, Shoichet MS. Hyaluronic acid click hydrogels emulate the extracellular matrix. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 7393-400. PMID 23343008 DOI: 10.1021/La305000W  0.557
2013 Chan DPY, Owen SC, Shoichet MS. Double click: Dual functionalized polymeric micelles with antibodies and peptides Bioconjugate Chemistry. 24: 105-113. PMID 23289801 DOI: 10.1021/Bc300511A  0.59
2012 Ho KS, Poon PC, Owen SC, Shoichet MS. Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: A comparison of ectopic and orthotopic tumours Bmc Cancer. 12. PMID 23217114 DOI: 10.1186/1471-2407-12-579  0.612
2012 Owen SC, Doak AK, Wassam P, Shoichet MS, Shoichet BK. Colloidal aggregation affects the efficacy of anticancer drugs in cell culture. Acs Chemical Biology. 7: 1429-35. PMID 22625864 DOI: 10.1021/Cb300189B  0.559
2012 Terry CM, Li L, Li H, Zhuplatov I, Blumenthal DK, Kim SE, Owen SC, Kholmovski EG, Fowers KD, Rathi R, Cheung AK. In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 459-67. PMID 22465391 DOI: 10.1016/J.Jconrel.2012.03.011  0.328
2012 Aizawa Y, Owen SC, Shoichet MS. Polymers used to influence cell fate in 3D geometry: New trends Progress in Polymer Science. 37: 645-658. DOI: 10.1016/J.Progpolymsci.2011.11.004  0.645
2012 Owen SC, Chan DPY, Shoichet MS. Polymeric micelle stability Nano Today. 7: 53-65. DOI: 10.1016/J.Nantod.2012.01.002  0.601
2011 Lu J, Owen SC, Shoichet MS. Stability of Self-Assembled Polymeric Micelles in Serum. Macromolecules. 44: 6002-6008. PMID 21818161 DOI: 10.1021/Ma200675W  0.706
2011 Nimmo CM, Owen SC, Shoichet MS. Diels-alder click cross-linked hyaluronic acid hydrogels for tissue engineering Biomacromolecules. 12: 824-830. PMID 21314111 DOI: 10.1021/Bm101446K  0.53
2011 Lu J, Owen SC, Shoichet MS. Stability of self-assembled polymeric micelles in serum Macromolecules. 44: 6002-6008. DOI: 10.1021/ma200675w  0.637
2010 Owen SC, Shoichet MS. Design of three-dimensional biomimetic scaffolds Journal of Biomedical Materials Research - Part A. 94: 1321-1331. PMID 20597126 DOI: 10.1002/Jbm.A.32834  0.518
2010 Owen SC, Li H, Sanders WG, Cheung AK, Terry CM. Correlation of tissue drug concentrations with in vivo magnetic resonance images of polymer drug depot around arteriovenous graft. Journal of Controlled Release : Official Journal of the Controlled Release Society. 146: 23-30. PMID 20457189 DOI: 10.1016/J.Jconrel.2010.05.005  0.384
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