Prem Kumar - Publications

Affiliations: 
University Laboratory of Physiology (now DPAG) University of Oxford, Oxford, United Kingdom 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Aldossary HS, Alzahrani AA, Nathanael D, Alhuthail EA, Ray CJ, Batis N, Kumar P, Coney AM, Holmes AP. G-Protein-Coupled Receptor (GPCR) Signaling in the Carotid Body: Roles in Hypoxia and Cardiovascular and Respiratory Disease. International Journal of Molecular Sciences. 21. PMID 32825527 DOI: 10.3390/Ijms21176012  0.33
2018 Holmes AP, Ray CJ, Coney AM, Kumar P. Is Carotid Body Physiological O Sensitivity Determined by a Unique Mitochondrial Phenotype? Frontiers in Physiology. 9: 562. PMID 29867584 DOI: 10.3389/Fphys.2018.00562  0.336
2018 Holmes AP, Ray CJ, Thompson EL, Alshehri Z, Coney AM, Kumar P. Adrenaline activation of the carotid body: key to CO and pH homeostasis in hypoglycaemia and potential pathological implications in cardiovascular disease. Respiratory Physiology & Neurobiology. PMID 29807139 DOI: 10.1016/J.Resp.2018.05.008  0.35
2017 Holmes AP, Ray CJ, Pearson SA, Coney AM, Kumar P. Ecto-5'-nucleotidase (CD73) regulates peripheral chemoreceptor activity and cardiorespiratory responses to hypoxia. The Journal of Physiology. PMID 28560821 DOI: 10.1113/Jp274498  0.356
2016 Thompson EL, Ray CJ, Holmes AP, Pye R, Wyatt CN, Coney AM, Kumar P. Adrenaline release evokes hyperpnoea and an increase in ventilatory CO2 sensitivity during hypoglycaemia: a role for the carotid body. The Journal of Physiology. PMID 27027261 DOI: 10.1113/Jp272191  0.37
2015 Mahmoud AD, Lewis S, Juričić L, Udoh UA, Hartmann S, Jansen MA, Ogunbayo OA, Puggioni P, Holmes AP, Kumar P, Navarro-Dorado J, Foretz M, Viollet B, Dutia MB, Marshall I, et al. AMPK Deficiency Blocks the Hypoxic Ventilatory Response and Thus Precipitates Hypoventilation and Apnea. American Journal of Respiratory and Critical Care Medicine. PMID 26669206 DOI: 10.1164/Rccm.201508-1667Oc  0.337
2015 Holmes AP, Turner PJ, Buckler KJ, Kumar P. Moderate inhibition of mitochondrial function augments carotid body hypoxic sensitivity. Pflugers Archiv : European Journal of Physiology. PMID 26490460 DOI: 10.1007/S00424-015-1745-X  0.367
2015 Holmes AP, Nunes AR, Cann MJ, Kumar P. Ecto-5'-Nucleotidase, Adenosine and Transmembrane Adenylyl Cyclase Signalling Regulate Basal Carotid Body Chemoafferent Outflow and Establish the Sensitivity to Hypercapnia. Advances in Experimental Medicine and Biology. 860: 279-89. PMID 26303492 DOI: 10.1007/978-3-319-18440-1_32  0.365
2015 Ray CJ, Dow B, Kumar P, Coney AM. Mild Chronic Intermittent Hypoxia in Wistar Rats Evokes Significant Cardiovascular Pathophysiology but No Overt Changes in Carotid Body-Mediated Respiratory Responses. Advances in Experimental Medicine and Biology. 860: 245-54. PMID 26303488 DOI: 10.1007/978-3-319-18440-1_28  0.316
2014 Holmes AP, Turner PJ, Carter P, Leadbeater W, Ray CJ, Hauton D, Buckler KJ, Kumar P. Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation. The Journal of Physiology. 592: 4493-506. PMID 25063821 DOI: 10.1113/Jphysiol.2014.276105  0.307
2013 Nunes AR, Holmes AP, Sample V, Kumar P, Cann MJ, Monteiro EC, Zhang J, Gauda EB. Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors. Respiratory Physiology & Neurobiology. 188: 83-93. PMID 23727159 DOI: 10.1016/J.Resp.2013.05.013  0.396
2013 Hauton D, Holmes A, Ziff O, Kumar P. The impact of acute and chronic catecholamines on respiratory responses to hypoxic stress in the rat. Pflã¼Gers Archiv : European Journal of Physiology. 465: 209-19. PMID 23291711 DOI: 10.1007/S00424-012-1210-Z  0.357
2012 Kumar P, Prabhakar NR. Peripheral chemoreceptors: function and plasticity of the carotid body. Comprehensive Physiology. 2: 141-219. PMID 23728973 DOI: 10.1002/Cphy.C100069  0.363
2012 Holmes AP, Hauton D, Kumar P. The interaction between low glucose and hypoxia in the in vitro, rat carotid body. Advances in Experimental Medicine and Biology. 758: 123-7. PMID 23080152 DOI: 10.1007/978-94-007-4584-1_17  0.353
2012 Evans AM, Peers C, Wyatt CN, Kumar P, Hardie DG. Ion channel regulation by the LKB1-AMPK signalling pathway: the key to carotid body activation by hypoxia and metabolic homeostasis at the whole body level. Advances in Experimental Medicine and Biology. 758: 81-90. PMID 23080146 DOI: 10.1007/978-94-007-4584-1_11  0.379
2012 Kumar P. The carotid body in cardiovascular disease: more chicken and egg than horse and cart? The Journal of Physiology. 590: 4123. PMID 22962032 DOI: 10.1113/Jphysiol.2012.239921  0.367
2012 Griffin HS, Pugh K, Kumar P, Balanos GM. Long-term facilitation of ventilation following acute continuous hypoxia in awake humans during sustained hypercapnia. The Journal of Physiology. 590: 5151-65. PMID 22826133 DOI: 10.1113/Jphysiol.2012.236109  0.305
2011 Casey DP, Imray CH, Wilson MH, Flouris AD, Carrillo AE, Tedjasaputra V, Hopkins SR, Birchard GF, Billat V, West JB, Vagula MC, Nelatury C, Bennet L, Gasier HG, Gunga HC, ... ... Kumar P, et al. Comments on point: counterpoint: high altitude is/is not for the birds! Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1520-4. PMID 22096211 DOI: 10.1152/Japplphysiol.01117.2011  0.349
2010 Lykidis CK, Kumar P, Vianna LC, White MJ, Balanos GM. A respiratory response to the activation of the muscle metaboreflex during concurrent hypercapnia in man. Experimental Physiology. 95: 194-201. PMID 19801386 DOI: 10.1113/Expphysiol.2009.049999  0.323
2009 Evans AM, Hardie DG, Peers C, Wyatt CN, Viollet B, Kumar P, Dallas ML, Ross F, Ikematsu N, Jordan HL, Barr BL, Rafferty JN, Ogunbayo O. Ion channel regulation by AMPK: the route of hypoxia-response coupling in thecarotid body and pulmonary artery. Annals of the New York Academy of Sciences. 1177: 89-100. PMID 19845611 DOI: 10.1111/J.1749-6632.2009.05041.X  0.424
2009 Kumar P. Systemic effects resulting from carotid body stimulation-invited article. Advances in Experimental Medicine and Biology. 648: 223-33. PMID 19536485 DOI: 10.1007/978-90-481-2259-2_26  0.394
2008 Wyatt CN, Pearson SA, Kumar P, Peers C, Hardie DG, Evans AM. Key roles for AMP-activated protein kinase in the function of the carotid body? Advances in Experimental Medicine and Biology. 605: 63-8. PMID 18085248 DOI: 10.1007/978-0-387-73693-8_11  0.385
2007 Sundin L, Burleson ML, Sanchez AP, Amin-Naves J, Kinkead R, Gargaglioni LH, Hartzler LK, Wiemann M, Kumar P, Glass ML. Respiratory chemoreceptor function in vertebrates comparative and evolutionary aspects. Integrative and Comparative Biology. 47: 592-600. PMID 21672865 DOI: 10.1093/Icb/Icm076  0.353
2007 Kumar P. Sensing hypoxia in the carotid body: From stimulus to response Essays in Biochemistry. 43: 43-60. PMID 17705792 DOI: 10.1042/Bse0430043  0.416
2007 Meng F, To W, Kirkman-Brown J, Kumar P, Gu Y. Calcium oscillations induced by ATP in human umbilical cord smooth muscle cells. Journal of Cellular Physiology. 213: 79-87. PMID 17477379 DOI: 10.1002/Jcp.21092  0.345
2007 Kumar P, Bin-Jaliah I. Adequate stimuli of the carotid body: More than an oxygen sensor? Respiratory Physiology and Neurobiology. 157: 12-21. PMID 17291838 DOI: 10.1016/J.Resp.2007.01.007  0.401
2007 Wyatt CN, Mustard KJ, Pearson SA, Dallas ML, Atkinson L, Kumar P, Peers C, Hardie DG, Evans AM. AMP-activated protein kinase mediates carotid body excitation by hypoxia. The Journal of Biological Chemistry. 282: 8092-8. PMID 17179156 DOI: 10.1074/Jbc.M608742200  0.375
2007 Kumar P. How sweet it is: Sensing low glucose in the carotid body Journal of Physiology. 578: 627. PMID 17170041 DOI: 10.1113/Jphysiol.2006.126250  0.353
2006 Evans AM, Hardie DG, Galione A, Peers C, Kumar P, Wyatt CN. AMP-activated protein kinase couples mitochondrial inhibition by hypoxia to cell-specific Ca2+ signalling mechanisms in oxygen-sensing cells. Novartis Foundation Symposium. 272: 234-52; discussion 2. PMID 16686439 DOI: 10.1002/9780470035009.Ch18  0.405
2006 Maskell PD, Rusius CJ, Whitehead KJ, Kumar P. Adrenaline increases carotid body CO2 sensitivity: an in vivo study Advances in Experimental Medicine and Biology.. 580: 245-250; discussion . PMID 16683727 DOI: 10.1007/0-387-31311-7_38  0.337
2005 Evans AM, Mustard KJ, Wyatt CN, Peers C, Dipp M, Kumar P, Kinnear NP, Hardie DG. Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells? The Journal of Biological Chemistry. 280: 41504-11. PMID 16199527 DOI: 10.1074/Jbc.M510040200  0.705
2005 Bin-Jaliah I, Maskell PD, Kumar P. Carbon dioxide sensitivity during hypoglycaemia-induced, elevated metabolism in the anaesthetized rat Journal of Physiology. 563: 883-893. PMID 15661819 DOI: 10.1113/Jphysiol.2004.080085  0.347
2004 Dubuis E, Kumar P, Gautier M, Girardin C, Vandier C. Acidosis abolishes the effect of repeated applications of ATP on pulmonary artery force and [Ca2+]i. Respiratory Physiology & Neurobiology. 141: 157-66. PMID 15239966 DOI: 10.1016/J.Resp.2004.04.011  0.371
2004 Bin-Jaliah I, Maskell PD, Kumar P. Indirect sensing of insulin-induced hypoglycaemia by the carotid body in the rat Journal of Physiology. 556: 255-266. PMID 14742728 DOI: 10.1113/Jphysiol.2003.058321  0.362
2002 Kumar P, Dubuis E, Vandier C. Regulation of K+ Currents by CO in Carotid Body type I Cells and Pulmonary Artery Smooth Muscle Cells Advances in Experimental Medicine and Biology. 536: 147-154. PMID 14635661 DOI: 10.1007/978-1-4419-9280-2_19  0.33
2002 Barbé C, Al-Hashem F, Conway AF, Dubuis E, Vandier C, Kumar P. A possible dual site of action for carbon monoxide-mediated chemoexcitation in the rat carotid body Journal of Physiology. 543: 933-945. PMID 12231649 DOI: 10.1113/Jphysiol.2001.015750  0.347
1999 Vandier C, Conway AF, Landauer RC, Kumar P. Presynaptic action of adenosine on a 4-aminopyridine-sensitive current in the rat carotid body Journal of Physiology. 515: 419-429. PMID 10050009 DOI: 10.1111/J.1469-7793.1999.419Ac.X  0.352
1998 Watanabe T, Kumar P, Hanson MA. Elevation of metabolic rate by pyrogen administration does not affect the gain of respiratory peripheral chemoreflexes in unanesthetized kittens Pediatric Research. 44: 357-362. PMID 9727713 DOI: 10.1203/00006450-199809000-00015  0.386
1997 Calder NA, Kumar P, Hanson MA. Development of carotid chemoreceptor dynamic and steady-state sensitivity to CO2 in the newborn lamb Journal of Physiology. 503: 187-194. PMID 9288686 DOI: 10.1111/J.1469-7793.1997.187Bi.X  0.352
1997 Hatton CJ, Carpenter E, Pepper DR, Kumar P, Peers C. Developmental changes in isolated rat type I carotid body cell K+ currents and their modulation by hypoxia. The Journal of Physiology. 501: 49-58. PMID 9174993 DOI: 10.1111/J.1469-7793.1997.049Bo.X  0.304
1996 Calder N, Kumar P, Hanson M. Dynamic sensitivity of carotid chemoreceptors to CO2 in the newborn lamb Advances in Experimental Medicine and Biology. 410: 391-396. PMID 9030331 DOI: 10.1007/978-1-4615-5891-0_61  0.385
1996 Kumar P, Landauer RC, Pepper DR. Modifications of carotid body CO2 chemosensitivity in vitro. Advances in Experimental Medicine and Biology. 410: 203-10. PMID 9030299 DOI: 10.1007/978-1-4615-5891-0_29  0.363
1996 Elnazir B, Marshall JM, Kumar P. Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine. The Journal of Physiology. 492: 573-85. PMID 9019551 DOI: 10.1113/Jphysiol.1996.Sp021330  0.372
1996 Watanabe T, Kumar P, Hanson MA. Development of respiratory chemoreflexes to hypoxia and CO2 in unanaesthetized kittens Respiration Physiology. 106: 247-254. PMID 9017843 DOI: 10.1016/S0034-5687(96)00077-1  0.364
1996 Watanabe T, Kumar P, Hanson MA. Effect of ambient temperature on respiratory chemoreflex in unanaesthetized kittens Respiration Physiology. 106: 239-246. PMID 9017842 DOI: 10.1016/S0034-5687(96)00076-X  0.335
1995 Kumar P, Landauer RC, Pepper DR. The postnatal potentiation of chemoreceptor sensitivity to O2 and CO2 in the in vitro rat carotid body is blunted by chronic hypoxaemia. Development of chemosensitivity. Advances in Experimental Medicine and Biology. 393: 317-22. PMID 8629506 DOI: 10.1007/978-1-4615-1933-1_60  0.419
1995 Landauer RC, Pepper DR, Kumar P. Effect of chronic hypoxaemia from birth upon chemosensitivity in the adult rat carotid body in vitro. The Journal of Physiology. 485: 543-50. PMID 7666373 DOI: 10.1113/Jphysiol.1995.Sp020750  0.352
1995 Pepper DR, Landauer RC, Kumar P. Postnatal development of CO2-O2 interaction in the rat carotid body in vitro. The Journal of Physiology. 485: 531-41. PMID 7666372 DOI: 10.1113/Jphysiol.1995.Sp020749  0.355
1994 Calder NA, Williams BA, Kumar P, Hanson MA. The respiratory response of healthy term infants to breath-by-breath alternations in inspired oxygen at two postnatal ages Pediatric Research. 35: 321-324. PMID 8190519 DOI: 10.1203/00006450-199403000-00008  0.35
1994 Calder NA, Williams BA, Smyth J, Boon AW, Kumar P, Hanson MA. Absence of ventilatory responses to alternating breaths of mild hypoxia and air in infants who have had bronchopulmonary dysplasia: Implications for the risk of sudden infant death Pediatric Research. 35: 677-681. PMID 7936817 DOI: 10.1203/00006450-199406000-00011  0.304
1994 Hanson M, Kumar P. Chemoreceptor function in the fetus and neonate Advances in Experimental Medicine and Biology. 360: 99-108. PMID 7872133 DOI: 10.1007/978-1-4615-2572-1_9  0.326
1994 Kumar P, Nye PC, Torrance RW. Proportional sensitivity of arterial chemoreceptors to CO2. Advances in Experimental Medicine and Biology. 360: 237-9. PMID 7872092 DOI: 10.1007/978-1-4615-2572-1_36  0.648
1991 Kumar P, Nye PC, Torrance RW. Effect of waveforms of inspired gas tension on the respiratory oscillations of carotid body discharge. Journal of Applied Physiology (Bethesda, Md. : 1985). 71: 271-9. PMID 1917750 DOI: 10.1152/Jappl.1991.71.1.271  0.653
1991 Williams BA, Smyth J, Boon AW, Hanson MA, Kumar P, Blanco CE. Development of respiratory chemoreflexes in response to alternations of fractional inspired oxygen in the newborn infant Journal of Physiology. 442: 81-90. PMID 1798051 DOI: 10.1113/Jphysiol.1991.Sp018783  0.333
1989 Hanson MA, Kumar P, Williams BA. The effect of chronic hypoxia upon the development of respiratory chemoreflexes in the newborn kitten Journal of Physiology. 411: 563-574. PMID 2614733 DOI: 10.1113/Jphysiol.1989.Sp017590  0.379
1988 Kumar P, Nye PC, Torrance RW. Do oxygen tension variations contribute to the respiratory oscillations of chemoreceptor discharge in the cat? The Journal of Physiology. 395: 531-52. PMID 3137326 DOI: 10.1113/Jphysiol.1988.Sp016933  0.662
1988 Blanco CE, Degraeuwe PLJ, Hanson MA, Kumar P, Williams BA. 113: CHEMOREFLEX RESPONSES TO ALTERNATIONS OF FiO2 IN THE NEWBORN INFANT Pediatric Research. 24: 279-279. DOI: 10.1203/00006450-198808000-00138  0.337
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