Joy Y. Wu, Ph.D. - Publications

Affiliations: 
2000 Duke University, Durham, NC 
Area:
cell signaling cascades that regulate cell proliferation, differentiation or function

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhu H, Su Y, Wang J, Wu JY. The role of vesicle trafficking genes in osteoblast differentiation and function. Scientific Reports. 13: 16079. PMID 37752218 DOI: 10.1038/s41598-023-43116-8  0.332
2023 Swami S, Zhu H, Nisco A, Kimura T, Kim MJ, Nair V, Wu JY. Parathyroid hormone receptor (PTH1R) signaling mediates breast cancer metastasis to bone in mice. Jci Insight. PMID 36692956 DOI: 10.1172/jci.insight.157390  0.313
2022 Swami S, Johnson J, Vecchi LA, Kim MJ, Lanske B, Johnson RW, Wu JY. Sex-Specific Differences in Gα-Mediated Signaling Downstream of PTH1R Activation by Abaloparatide in Bone. Jbmr Plus. 6: e10695. PMID 36530190 DOI: 10.1002/jbm4.10695  0.367
2022 Kim MJ, Valderrábano RJ, Wu JY. Osteoblast Lineage Support of Hematopoiesis in Health and Disease. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 35983701 DOI: 10.1002/jbmr.4678  0.344
2022 Kimura T, Panaroni C, Rankin EB, Purton LE, Wu JY. Loss of parathyroid hormone receptor signaling in osteoprogenitors is associated with accumulation of multiple hematopoietic lineages in the bone marrow. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 35490308 DOI: 10.1002/jbmr.4568  0.392
2022 Hirata H, Zhang N, Ueno M, Barati D, Kushioka J, Shen H, Tsubosaka M, Toya M, Lin T, Huang E, Yao Z, Wu JY, Zwingenberger S, Yang F, Goodman SB. Ageing attenuates bone healing by mesenchymal stem cells in a microribbon hydrogel with a murine long bone critical-size defect model. Immunity & Ageing : I & A. 19: 14. PMID 35279175 DOI: 10.1186/s12979-022-00272-1  0.339
2021 Ueno M, Zhang N, Hirata H, Barati D, Utsunomiya T, Shen H, Lin T, Maruyama M, Huang E, Yao Z, Wu JY, Zwingenberger S, Yang F, Goodman SB. Sex Differences in Mesenchymal Stem Cell Therapy With Gelatin-Based Microribbon Hydrogels in a Murine Long Bone Critical-Size Defect Model. Frontiers in Bioengineering and Biotechnology. 9: 755964. PMID 34738008 DOI: 10.3389/fbioe.2021.755964  0.35
2021 Green AC, Tjin G, Lee SC, Chalk AM, Straszkowski L, Kwang D, Baker EK, Quach JM, Kimura T, Wu J, Purton LE. The characterization of distinct populations of murine skeletal cells that have different roles in B lymphopoiesis. Blood. PMID 33786586 DOI: 10.1182/blood.2020005865  0.365
2021 Shapiro F, Maguire K, Swami S, Zhu H, Flynn E, Wang J, Wu JY. Histopathology of osteogenesis imperfecta bone. Supramolecular assessment of cells and matrices in the context of woven and lamellar bone formation using light, polarization and ultrastructural microscopy. Bone Reports. 14: 100734. PMID 33665234 DOI: 10.1016/j.bonr.2020.100734  0.347
2020 Bar M, Ott SM, Lewiecki EM, Sarafoglou K, Wu JY, Thompson MJ, Vaux JJ, Dean DR, Saag KG, Hashmi SK, Inamoto Y, Dholaria BR, Kharfan-Dabaja MA, Nagler A, Rodriguez C, et al. Bone Health Management After Hematopoietic Cell Transplantation: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 32653624 DOI: 10.1016/J.Bbmt.2020.07.001  0.387
2020 Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, ... Wu JY, ... Wu JC, et al. Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes. Cell Stem Cell. 27: 50-63.e5. PMID 32619518 DOI: 10.1016/J.Stem.2020.06.001  0.301
2020 Zhu H, Wu JY. Induction of Osteoblasts by Direct Reprogramming of Mouse Fibroblasts. Methods in Molecular Biology (Clifton, N.J.). 2155: 201-212. PMID 32474879 DOI: 10.1007/978-1-0716-0655-1_17  0.435
2020 Lin T, Pajarinen J, Kohno Y, Nabeshima A, Lu L, Nathan K, Yao Z, Wu JY, Goodman S. Increased NF-kB activity in osteoprogenitor-lineage cells impairs the balance of bone versus fat in the marrow of skeletally mature mice. Regenerative Engineering and Translational Medicine. 6: 69-77. PMID 32377560 DOI: 10.1007/s40883-019-00112-7  0.36
2019 Zhu H, Swami S, Yang P, Shapiro F, Wu J. Direct reprogramming of mouse fibroblasts into functional osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31793059 DOI: 10.1002/Jbmr.3929  0.476
2019 Shapiro F, Wu JY. Woven bone overview: structural classification based on its integral role in developmental, repair and pathological bone formation throughout vertebrate groups. European Cells & Materials. 38: 137-167. PMID 31571191 DOI: 10.22203/Ecm.V038A11  0.445
2019 Lin TH, Kohno Y, Huang JF, Romero-Lopez M, Maruyama M, Ueno M, Pajarinen J, Nathan K, Yao Z, Yang F, Wu J, Goodman SB. Preconditioned or IL4-Secreting Mesenchymal Stem Cells Enhanced Osteogenesis at Different Stages. Tissue Engineering. Part A. PMID 30652628 DOI: 10.1089/Ten.Tea.2018.0292  0.366
2018 Valderrábano RJ, Buzkova P, Chang PY, Zakai NA, Fink HA, Robbins JA, Lee JS, Wu JY. Association of bone mineral density with hemoglobin and change in hemoglobin among older men and women: The cardiovascular health study. Bone. PMID 30448304 DOI: 10.1016/J.Bone.2018.11.010  0.411
2018 Valderrábano RJ, Wu JY. Bone and blood interactions in human health and disease. Bone. PMID 29476979 DOI: 10.1016/J.Bone.2018.02.019  0.441
2018 Karaca A, Malladi VR, Zu Y, Tafaj O, Paltrinieri E, Wu JY, He Q, Bastepe M. Constitutive stimulatory G protein activity in limb mesenchyme impairs bone growth. Bone. PMID 29471062 DOI: 10.1016/J.Bone.2018.02.016  0.473
2018 Zhu H, Kimura T, Swami S, Wu JY. Pluripotent stem cells as a source of osteoblasts for bone tissue regeneration. Biomaterials. PMID 29456164 DOI: 10.1016/J.Biomaterials.2018.02.009  0.446
2017 Green AC, Rudolph-Stringer V, Chantry AD, Wu JY, Purton LE. Mesenchymal lineage cells and their importance in B lymphocyte niches. Bone. PMID 29183783 DOI: 10.1016/J.Bone.2017.11.018  0.44
2017 Swami S, Johnson J, Bettinson LA, Kimura T, Zhu H, Albertelli MA, Johnson RW, Wu JY. Prevention of breast cancer skeletal metastases with parathyroid hormone. Jci Insight. 2. PMID 28878134 DOI: 10.1172/Jci.Insight.90874  0.405
2017 Chubb R, Oh J, Riley AK, Kimura T, Wu SM, Wu JY. In vivo rescue of the hematopoietic niche by pluripotent stem cell complementation of defective osteoblast compartments. Stem Cells (Dayton, Ohio). PMID 28741855 DOI: 10.1002/Stem.2670  0.5
2017 Pierini A, Nishikii H, Baker J, Kimura T, Kwon HS, Pan Y, Chen Y, Alvarez M, Strober W, Velardi A, Shizuru JA, Wu JY, Chiba S, Negrin RS. Foxp3(+) regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis. Nature Communications. 8: 15068. PMID 28485401 DOI: 10.1038/Ncomms15068  0.439
2017 Valderrábano RJ, Lee J, Lui LY, Hoffman AR, Cummings SR, Orwoll ES, Wu JY. Older Men with Anemia Have Increased Fracture Risk Independent of Bone Mineral Density. The Journal of Clinical Endocrinology and Metabolism. PMID 28368469 DOI: 10.1210/Jc.2017-00266  0.345
2017 Ramaswamy G, Kim H, Zhang D, Lounev V, Wu JY, Choi Y, Kaplan FS, Pignolo RJ, Shore EM. Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways. Scientific Reports. 7: 45140. PMID 28338087 DOI: 10.1038/Srep45140  0.475
2017 Fan Y, Hanai JI, Le PT, Bi R, Maridas D, DeMambro V, Figueroa CA, Kir S, Zhou X, Mannstadt M, Baron R, Bronson RT, Horowitz MC, Wu JY, Bilezikian JP, et al. Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate. Cell Metabolism. PMID 28162969 DOI: 10.1016/J.Cmet.2017.01.001  0.496
2016 Chaudhary N, Lee JS, Wu JY, Tharin S. Evidence for use of Teriparatide in Spinal Fusion Surgery in Osteoporotic Patients. World Neurosurgery. PMID 27923758 DOI: 10.1016/J.Wneu.2016.11.135  0.366
2016 Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, ... ... Wu JY, et al. SIKs control osteocyte responses to parathyroid hormone. Nature Communications. 7: 13176. PMID 27759007 DOI: 10.1038/Ncomms13176  0.415
2016 Valderrábano RJ, Lui LY, Lee J, Cummings SR, Orwoll ES, Hoffman AR, Wu JY. Bone Density Loss Is Associated with Blood Cell Counts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27653240 DOI: 10.1002/Jbmr.3000  0.368
2016 Johnson RW, Finger EC, Olcina MM, Vilalta M, Aguilera T, Miao Y, Merkel AR, Johnson JR, Sterling JA, Wu JY, Giaccia AJ. Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow. Nature Cell Biology. PMID 27642788 DOI: 10.1038/Ncb3408  0.383
2016 Nishikii H, Pierini A, Yokoyama Y, Kimura T, Kwon H, Alvarez M, Baker J, Shizuru J, Wu J, Chiba S, Negrin RS. Foxp3+ regulatory T Cells Maintain Bone Marrow Microenvironment for B Cell Differentiation from Hematopoietic Stem Cells Blood. 128: 431-431. DOI: 10.1182/Blood.V128.22.431.431  0.415
2016 Wu J, Kimura T, Keller T, Purton L, Rankin E. Parathyroid hormone receptor signaling in osteoprogenitors regulates erythropoiesis in the bone marrow and spleen Experimental Hematology. 44: S63-S64. DOI: 10.1016/J.Exphem.2016.06.106  0.413
2015 Sinha P, Aarnisalo P, Chubb R, Poulton IJ, Guo J, Nachtrab G, Kimura T, Swami S, Saeed H, Chen M, Weinstein LS, Schipani E, Sims NA, Kronenberg HM, Wu JY. Loss of Gsα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy. The Journal of Biological Chemistry. PMID 26598522 DOI: 10.1074/Jbc.M115.679753  0.478
2015 Wu JY. Pluripotent Stem Cells and Skeletal Regeneration-Promise and Potential. Current Osteoporosis Reports. 13: 342-50. PMID 26260198 DOI: 10.1007/S11914-015-0285-9  0.435
2015 Panaroni C, Fulzele K, Saini V, Chubb R, Pajevic PD, Wu JY. PTH Signaling in Osteoprogenitors Is Essential for B-Lymphocyte Differentiation and Mobilization. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26191777 DOI: 10.1002/Jbmr.2581  0.438
2015 Yu VW, Saez B, Cook C, Lotinun S, Pardo-Saganta A, Wang YH, Lymperi S, Ferraro F, Raaijmakers MH, Wu JY, Zhou L, Rajagopal J, Kronenberg HM, Baron R, Scadden DT. Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow. The Journal of Experimental Medicine. 212: 759-74. PMID 25918341 DOI: 10.1084/Jem.20141843  0.478
2015 Green AC, Poulton IJ, Vrahnas C, Häusler KD, Walkley CR, Wu JY, Martin TJ, Gillespie MT, Chandraratna RA, Quinn JM, Sims NA, Purton LE. RARγ is a negative regulator of osteoclastogenesis. The Journal of Steroid Biochemistry and Molecular Biology. 150: 46-53. PMID 25800721 DOI: 10.1016/J.Jsbmb.2015.03.005  0.482
2014 Tan SH, Senarath-Yapa K, Chung MT, Longaker MT, Wu JY, Nusse R. Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 111: E5262-71. PMID 25422448 DOI: 10.1073/Pnas.1420463111  0.442
2014 Sinha P, Aarnisalo P, Chubb R, Ono N, Fulzele K, Selig M, Saeed H, Chen M, Weinstein LS, Pajevic PD, Kronenberg HM, Wu JY. Loss of Gsα early in the osteoblast lineage favors adipogenic differentiation of mesenchymal progenitors and committed osteoblast precursors. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 2414-26. PMID 24806274 DOI: 10.1002/Jbmr.2270  0.504
2014 Pellicelli M, Miller JA, Arabian A, Gauthier C, Akhouayri O, Wu JY, Kronenberg HM, St-Arnaud R. The PTH-Gαs-protein kinase A cascade controls αNAC localization to regulate bone mass. Molecular and Cellular Biology. 34: 1622-33. PMID 24550008 DOI: 10.1128/Mcb.01434-13  0.444
2014 Panaroni C, Tzeng YS, Saeed H, Wu JY. Mesenchymal progenitors and the osteoblast lineage in bone marrow hematopoietic niches. Current Osteoporosis Reports. 12: 22-32. PMID 24477415 DOI: 10.1007/S11914-014-0190-7  0.486
2014 Yu EW, Kumbhani R, Siwila-Sackman E, DeLelys M, Preffer FI, Leder BZ, Wu JY. Teriparatide (PTH 1-34) treatment increases peripheral hematopoietic stem cells in postmenopausal women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 1380-6. PMID 24420643 DOI: 10.1002/Jbmr.2171  0.397
2013 Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT. Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nature Medicine. 19: 1513-7. PMID 24162813 DOI: 10.1038/Nm.3364  0.466
2013 Panaroni C, Wu JY. Interactions between B lymphocytes and the osteoblast lineage in bone marrow. Calcified Tissue International. 93: 261-8. PMID 23839529 DOI: 10.1007/S00223-013-9753-3  0.474
2013 Fulzele K, Krause DS, Panaroni C, Saini V, Barry KJ, Liu X, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Wu JY, Kronenberg HM, Scadden DT, et al. Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood. 121: 930-9. PMID 23160461 DOI: 10.1182/Blood-2012-06-437160  0.498
2012 Santo L, Cirstea D, Wang B, Yao T, Wu JY, Waterman P, Jeon D, Bouxsein M, Louis L, Lotinun S, Baron R, Eda H, Nemani N, Mahindra A, Yee AJ, et al. Role of Selective HDAC6 Inhibition On Multiple Myeloma Bone Disease Blood. 120: 328-328. DOI: 10.1182/Blood.V120.21.328.328  0.466
2011 Wu JY, Aarnisalo P, Bastepe M, Sinha P, Fulzele K, Selig MK, Chen M, Poulton IJ, Purton LE, Sims NA, Weinstein LS, Kronenberg HM. Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice. The Journal of Clinical Investigation. 121: 3492-504. PMID 21804192 DOI: 10.1172/Jci46406  0.504
2011 Mariot V, Wu JY, Aydin C, Mantovani G, Mahon MJ, Linglart A, Bastepe M. Potent constitutive cyclic AMP-generating activity of XLαs implicates this imprinted GNAS product in the pathogenesis of McCune-Albright syndrome and fibrous dysplasia of bone. Bone. 48: 312-20. PMID 20887824 DOI: 10.1016/J.Bone.2010.09.032  0.409
2011 Krause DS, Fulzele K, Catic A, Hurley M, Lezeau S, Hasserjian R, Wu J, Divieti-Pajevic P, Van Etten RA, Schipani E, Scadden DT. Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Reduces Leukemic Stem Cells in Murine Chronic Myelogenous-Leukemia-Like Disease Via a TGFbeta-Dependent Pathway Blood. 118: 1670-1670. DOI: 10.1182/Blood.V118.21.1670.1670  0.474
2009 Wu JY, Scadden DT, Kronenberg HM. Role of the osteoblast lineage in the bone marrow hematopoietic niches. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 759-64. PMID 19257832 DOI: 10.1359/Jbmr.090225  0.486
2008 Wu JY, Purton LE, Rodda SJ, Chen M, Weinstein LS, McMahon AP, Scadden DT, Kronenberg HM. Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 16976-81. PMID 18957542 DOI: 10.1073/Pnas.0802898105  0.389
2001 Wu JY, Ribar TJ, Means AR. Spermatogenesis and the regulation of Ca(2+)-calmodulin-dependent protein kinase IV localization are not dependent on calspermin. Molecular and Cellular Biology. 21: 6066-70. PMID 11486043 DOI: 10.1128/Mcb.21.17.6066-6070.2001  0.514
2000 Wu JY, Gonzalez-Robayna IJ, Richards JS, Means AR. Female Fertility Is Reduced in Mice Lacking Ca2+/Calmodulin-Dependent Protein Kinase IV* *This work was supported by an NIH Medical Scientist Training Program award (to J.Y.W.) and NIH Grants HD-07503 (to A.R.M.) and HD-1272 (to J.S.R.). Endocrinology. 141: 4777-4783. PMID 28200902 DOI: 10.1210/endo.141.12.7826  0.396
2000 Wu JY, Gonzalez-Robayna IJ, Richards JS, Means AR. Female fertility is reduced in mice lacking Ca2+/calmodulin-dependent protein kinase IV. Endocrinology. 141: 4777-83. PMID 11108293 DOI: 10.1210/Endo.141.12.7826  0.537
2000 Wu JY, Ribar TJ, Cummings DE, Burton KA, McKnight GS, Means AR. Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. Nature Genetics. 25: 448-52. PMID 10932193 DOI: 10.1038/78153  0.53
2000 Wu JY, Means AR. Ca(2+)/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix. The Journal of Biological Chemistry. 275: 7994-9. PMID 10713118 DOI: 10.1074/Jbc.275.11.7994  0.501
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