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Zachary P. Demko, Ph.D. - Publications

Affiliations: 
2002 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Click chemistry
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hedriana H, Martin K, Saltzman D, Billings P, Demko Z, Benn P. Cell Free DNA fetal fraction in twin gestations in single nucleotide polymorphism-based non-invasive prenatal screening. Prenatal Diagnosis. PMID 31711265 DOI: 10.1002/Pd.5609  0.353
2019 DiNonno W, Demko Z, Martin K, Billings P, Egbert M, Zneimer S, Keen-Kim D, Benn P. Quality Assurance of Non-Invasive Prenatal Screening (NIPS) for Fetal Aneuploidy Using Positive Predictive Values as Outcome Measures. Journal of Clinical Medicine. 8. PMID 31454954 DOI: 10.3390/Jcm8091311  0.335
2019 Norwitz ER, McNeill G, Kalyan A, Rivers E, Ahmed E, Meng L, Vu P, Egbert M, Shapira M, Kobara K, Parmar S, Goel S, Prins SA, Aruh I, Persico N, ... ... Demko ZP, et al. Validation of a Single-Nucleotide Polymorphism-Based Non-Invasive Prenatal Test in Twin Gestations: Determination of Zygosity, Individual Fetal Sex, and Fetal Aneuploidy. Journal of Clinical Medicine. 8. PMID 31261782 DOI: 10.3390/Jcm8070937  0.371
2018 Benn P, Valenti E, Shah S, Martin K, Demko Z. Factors Associated With Informative Redraw After an Initial No Result in Noninvasive Prenatal Testing. Obstetrics and Gynecology. PMID 29995728 DOI: 10.1097/Aog.0000000000002728  0.327
2018 Simon AL, Kiehl M, Fischer E, Proctor JG, Bush MR, Givens C, Rabinowitz M, Demko ZP. Pregnancy outcomes from more than 1,800 in vitro fertilization cycles with the use of 24-chromosome single-nucleotide polymorphism-based preimplantation genetic testing for aneuploidy. Fertility and Sterility. PMID 29908770 DOI: 10.1016/J.Fertnstert.2018.03.026  0.35
2018 McCoy RC, Newnham LJ, Ottolini CS, Hoffmann ER, Chatzimeletiou K, Cornejo OE, Zhan Q, Zaninovic N, Rosenwaks Z, Petrov DA, Demko ZP, Sigurjonsson S, Handyside AH. Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos. Human Molecular Genetics. PMID 29688390 DOI: 10.1093/Hmg/Ddy147  0.342
2018 Ravi H, McNeill G, Goel S, Meltzer SD, Hunkapiller N, Ryan A, Levy B, Demko ZP. Validation of a SNP-based non-invasive prenatal test to detect the fetal 22q11.2 deletion in maternal plasma samples. Plos One. 13: e0193476. PMID 29474437 DOI: 10.1371/Journal.Pone.0193476  0.374
2018 Ryan A, Iyengar S, Demko Z. Increased Positive Predictive Value for a Single-Nucleotide Polymorphism-Based Non-invasive Prenatal Test for the 22q11.2 Deletion Journal of Fetal Medicine. 5: 65-67. DOI: 10.1007/S40556-018-0153-7  0.356
2017 Martin K, Iyengar S, Kalyan A, Lan C, Simon AL, Stosic M, Kobara K, Ravi H, Truong T, Ryan A, Demko ZP, Benn P. Clinical Experience with a Single-Nucleotide Polymorphism-Based Noninvasive Prenatal Test for Five Clinically Significant Microdeletions. Clinical Genetics. PMID 28696552 DOI: 10.1111/Cge.13098  0.328
2016 Ryan A, Hunkapiller N, Banjevic M, Vankayalapati N, Fong N, Jinnett KN, Demko Z, Zimmermann B, Sigurjonsson S, Gross SJ, Hill M. Validation of an Enhanced Version of a Single-Nucleotide Polymorphism-Based Noninvasive Prenatal Test for Detection of Fetal Aneuploidies. Fetal Diagnosis and Therapy. PMID 27028530 DOI: 10.1159/000442931  0.368
2016 Demko ZP, Simon AL, McCoy RC, Petrov DA, Rabinowitz M. Effects of maternal age on euploidy in a large cohort of embryos analyzed with 24-chromosome single-nucleotide polymorphism-based preimplantation genetic screening. Fertility and Sterility. PMID 26868992 DOI: 10.1016/J.Fertnstert.2016.01.025  0.333
2015 McCoy RC, Demko ZP, Ryan A, Banjevic M, Hill M, Sigurjonsson S, Rabinowitz M, Petrov DA. Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development. Plos Genetics. 11: e1005601. PMID 26491874 DOI: 10.1371/Journal.Pgen.1005601  0.333
2015 Gross SJ, Stosic M, McDonald-McGinn DM, Bassett AS, Norvez A, Dhamankar R, Kobara K, Kirkizlar E, Zimmermann B, Wayham N, Babiarz JE, Ryan A, Jinnett KN, Demko Z, Benn P. Clinical Experience with Single-Nucleotide Polymorphism-Based Noninvasive Prenatal Screening for 22q11.2 Deletion Syndrome. Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology. PMID 26396068 DOI: 10.1002/Uog.15754  0.366
2015 McCoy RC, Demko Z, Ryan A, Banjevic M, Hill M, Sigurjonsson S, Rabinowitz M, Fraser HB, Petrov DA. Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos. Science (New York, N.Y.). 348: 235-8. PMID 25859044 DOI: 10.1097/Ogx.0000000000000223  0.337
2015 Simon AL, Su B, Demko Z, Rabinowitz M, Harmon ER, Gross SJ. Detection of a complete molar pregnancy by single nucleotide polymorphism-based noninvasive prenatal testing. Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology. PMID 25810270 DOI: 10.1002/Uog.14854  0.35
2015 Wapner RJ, Babiarz JE, Levy B, Stosic M, Zimmermann B, Sigurjonsson S, Wayham N, Ryan A, Banjevic M, Lacroute P, Hu J, Hall MP, Demko Z, Siddiqui A, Rabinowitz M, et al. Expanding the scope of noninvasive prenatal testing: detection of fetal microdeletion syndromes. American Journal of Obstetrics and Gynecology. 212: 332.e1-9. PMID 25479548 DOI: 10.1016/J.Ajog.2014.11.041  0.368
2015 Curnow KJ, Wilkins-Haug L, Ryan A, K?rk?zlar E, Stosic M, Hall MP, Sigurjonsson S, Demko Z, Rabinowitz M, Gross SJ. Detection of triploid, molar, and vanishing twin pregnancies by a single-nucleotide polymorphism-based noninvasive prenatal test. American Journal of Obstetrics and Gynecology. 212: 79.e1-9. PMID 25447960 DOI: 10.1016/J.Ajog.2014.10.012  0.37
2015 Wapner RJ, Babiarz JE, Levy B, Stosic M, Zimmermann B, Sigurjonsson S, Wayham N, Ryan A, Banjevic M, Lacroute P, Hu J, Hall MP, Demko Z, Siddiqui A, Rabinowitz M, et al. Expanding the Scope of Noninvasive Prenatal Testing: Detection of Fetal Microdeletion Syndromes Obstetrical & Gynecological Survey. 70: 481-482. DOI: 10.1097/01.Ogx.0000470656.81447.E7  0.316
2014 Dar P, Curnow KJ, Gross SJ, Hall MP, Stosic M, Demko Z, Zimmermann B, Hill M, Sigurjonsson S, Ryan A, Banjevic M, Kolacki PL, Koch SW, Strom CM, Rabinowitz M, et al. Clinical experience and follow-up with large scale single-nucleotide polymorphism-based noninvasive prenatal aneuploidy testing. American Journal of Obstetrics and Gynecology. 211: 527.e1-527.e17. PMID 25111587 DOI: 10.1016/J.Ajog.2014.08.006  0.359
2014 Pergament E, Cuckle H, Zimmermann B, Banjevic M, Sigurjonsson S, Ryan A, Hall MP, Dodd M, Lacroute P, Stosic M, Chopra N, Hunkapiller N, Prosen DE, McAdoo S, Demko Z, et al. Single-nucleotide polymorphism-based noninvasive prenatal screening in a high-risk and low-risk cohort. Obstetrics and Gynecology. 124: 210-8. PMID 25004354 DOI: 10.1097/Aog.0000000000000363  0.309
2014 Levy B, Sigurjonsson S, Pettersen B, Maisenbacher MK, Hall MP, Demko Z, Lathi RB, Tao R, Aggarwal V, Rabinowitz M. Genomic imbalance in products of conception: single-nucleotide polymorphism chromosomal microarray analysis. Obstetrics and Gynecology. 124: 202-9. PMID 25004334 DOI: 10.1097/Aog.0000000000000325  0.37
2014 Hall MP, Hill M, Zimmermann B, Sigurjonsson S, Westemeyer M, Saucier J, Demko Z, Rabinowitz M. Non-invasive prenatal detection of trisomy 13 using a single nucleotide polymorphism- and informatics-based approach. Plos One. 9: e96677. PMID 24805989 DOI: 10.1371/Journal.Pone.0096677  0.387
2013 Saucier J, Merrion K, Mash J, Pettersen B, Hall M, Demko Z. Letter to the editor by megan Hall. Current Genomics. 14: 79-79. PMID 24082818 DOI: 10.2174/1389202911314020001  0.36
2013 Samango-Sprouse C, Banjevic M, Ryan A, Sigurjonsson S, Zimmermann B, Hill M, Hall MP, Westemeyer M, Saucier J, Demko Z, Rabinowitz M. SNP-based non-invasive prenatal testing detects sex chromosome aneuploidies with high accuracy. Prenatal Diagnosis. 33: 643-9. PMID 23712453 DOI: 10.1002/Pd.4159  0.387
2013 Ryan A, Baner J, Demko Z, Hill M, Sigurjonsson S, Baird ML, Rabinowitz M. Informatics-based, highly accurate, noninvasive prenatal paternity testing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 473-7. PMID 23258349 DOI: 10.1038/Gim.2012.155  0.356
2013 Rabinowitz M, Hill M, Demko Z, McAdoo S, Zimmermann B, Levy B. 591: Using targeted sequencing of SNPs to achieve a highly accurate non-invasive detection of fetal aneuploidy of 13, 18, 21 and sex chromosomes American Journal of Obstetrics and Gynecology. 208. DOI: 10.1016/J.Ajog.2012.10.757  0.38
2012 Zimmermann B, Hill M, Gemelos G, Demko Z, Banjevic M, Baner J, Ryan A, Sigurjonsson S, Chopra N, Dodd M, Levy B, Rabinowitz M. Noninvasive prenatal aneuploidy testing of chromosomes 13, 18, 21, X, and Y, using targeted sequencing of polymorphic loci. Prenatal Diagnosis. 32: 1233-41. PMID 23108718 DOI: 10.1002/Pd.3993  0.374
2012 Lathi RB, Massie JA, Loring M, Demko ZP, Johnson D, Sigurjonsson S, Gemelos G, Rabinowitz M. Informatics enhanced SNP microarray analysis of 30 miscarriage samples compared to routine cytogenetics. Plos One. 7: e31282. PMID 22403611 DOI: 10.1371/Journal.Pone.0031282  0.35
2012 Rabinowitz M, Ryan A, Gemelos G, Hill M, Baner J, Cinnioglu C, Banjevic M, Potter D, Petrov DA, Demko Z. Origins and rates of aneuploidy in human blastomeres. Fertility and Sterility. 97: 395-401. PMID 22195772 DOI: 10.1016/J.Fertnstert.2011.11.034  0.326
2012 Demko Z, Zimmermann B, Rabinowitz M. Non-invasive prenatal testing for whole chromosome abnormalities Laboratoriumsmedizin. 36: 263-267. DOI: 10.1515/Labmed-2012-0026  0.365
2012 Rabinowitz M, Gemelos G, Hill M, Demko Z, McAdoo S, Levy B. Noninvasive prenatal aneuploidy testing of chromosomes 13, 18, 21, X, and Y Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.107  0.306
2003 Himo F, Demko ZP, Noodleman L, Sharpless KB. Why is tetrazole formation by addition of azide to organic nitriles catalyzed by zinc(II) salts? Journal of the American Chemical Society. 125: 9983-7. PMID 12914461 DOI: 10.1021/Ja030204Q  0.426
2002 Demko ZP, Sharpless KB. A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-acyltetrazoles from azides and acyl cyanides. Angewandte Chemie (International Ed. in English). 41: 2113-6. PMID 19746613 DOI: 10.1002/1521-3773(20020617)41:12<2113::AID-ANIE2113>3.0.CO;2-Q  0.371
2002 Demko ZP, Sharpless KB. A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-sulfonyl tetrazoles from azides and sulfonyl cyanides. Angewandte Chemie (International Ed. in English). 41: 2110-3. PMID 19746612 DOI: 10.1002/1521-3773(20020617)41:12<2110::Aid-Anie2110>3.0.Co;2-7  0.432
2002 Himo F, Demko ZP, Noodleman L, Sharpless KB. Mechanisms of tetrazole formation by addition of azide to nitriles. Journal of the American Chemical Society. 124: 12210-6. PMID 12371861 DOI: 10.1021/Ja0206644  0.44
2002 Demko ZP, Sharpless KB. An expedient route to the tetrazole analogues of alpha-amino acids. Organic Letters. 4: 2525-7. PMID 12123367 DOI: 10.1021/Ol020096X  0.412
2002 Demko ZP, Sharpless KB. A Click Chemistry Approach to Tetrazoles by Huisgen 1,3-Dipolar Cycloaddition: Synthesis of 5-Acyltetrazoles from Azides and Acyl Cyanides We thank the National Institute of General Medical Sciences, National Institutes of Health (GM-28384), the National Science Foundation (CHE-9985553), the Skaggs Institute for Chemical Biology for a Predoctoral Fellowship (Z.D.), and the W. M. Keck Foundation for financial support. Angewandte Chemie. 114: 2217. DOI: 10.1002/1521-3757(20020617)114:12<2217::Aid-Ange2217>3.0.Co;2-X  0.403
2001 Demko ZP, Sharpless KB. An intramolecular [2 + 3] cycloaddition route to fused 5-heterosubstituted tetrazoles. Organic Letters. 3: 4091-4. PMID 11735592 DOI: 10.1021/Ol010220X  0.369
2001 Demko ZP, Sharpless KB. Preparation of 5-substituted 1H-tetrazoles from nitriles in water. The Journal of Organic Chemistry. 66: 7945-50. PMID 11722189 DOI: 10.1021/Jo010635W  0.363
2000 Demko ZP, Bartsch M, Sharpless KB. Primary amides. A general nitrogen source for catalytic asymmetric aminohydroxylation of olefins. Organic Letters. 2: 2221-3. PMID 10930248 DOI: 10.1021/Ol000098M  0.427
2000 Demko ZP, Bartsch M, Sharpless KB. ChemInform Abstract: Primary Amides. A General Nitrogen Source for Catalytic Asymmetric Aminohydroxylation of Olefins. Cheminform. 31: no-no. DOI: 10.1002/chin.200045098  0.349
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