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Catherine E. Leimkuhler, Ph.D. - Publications

Affiliations: 
2006 Harvard University, Cambridge, MA, United States 
Area:
molecular mechanisms of various antibiotics
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Leimkuhler C, Fridman M, Lupoli T, Walker S, Walsh CT, Kahne D. Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A. Journal of the American Chemical Society. 129: 10546-50. PMID 17685523 DOI: 10.1021/Ja072909O  0.702
2007 Howard-Jones AR, Kruger RG, Lu W, Tao J, Leimkuhler C, Kahne D, Walsh CT. Kinetic analysis of teicoplanin glycosyltransferases and acyltransferase reveal ordered tailoring of aglycone scaffold to reconstitute mature teicoplanin. Journal of the American Chemical Society. 129: 10082-3. PMID 17661468 DOI: 10.1021/Ja0735857  0.584
2006 Adachi M, Zhang Y, Leimkuhler C, Sun B, LaTour JV, Kahne DE. Degradation and reconstruction of moenomycin A and derivatives: dissecting the function of the isoprenoid chain. Journal of the American Chemical Society. 128: 14012-3. PMID 17061868 DOI: 10.1021/Ja065905C  0.586
2005 Yuan Y, Chung HS, Leimkuhler C, Walsh CT, Kahne D, Walker S. In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. Journal of the American Chemical Society. 127: 14128-9. PMID 16218575 DOI: 10.1021/Ja053704N  0.666
2005 Oberthür M, Leimkuhler C, Kruger RG, Lu W, Walsh CT, Kahne D. A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases. Journal of the American Chemical Society. 127: 10747-52. PMID 16045364 DOI: 10.1021/Ja052945S  0.636
2005 Lu W, Leimkuhler C, Gatto GJ, Kruger RG, Oberthür M, Kahne D, Walsh CT. AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. Chemistry & Biology. 12: 527-34. PMID 15911373 DOI: 10.1016/J.Chembiol.2005.02.016  0.591
2005 Leimkuhler C, Chen L, Barrett D, Panzone G, Sun B, Falcone B, Oberthür M, Donadio S, Walker S, Kahne D. Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. Journal of the American Chemical Society. 127: 3250-1. PMID 15755121 DOI: 10.1021/Ja043849E  0.671
2005 Barrett D, Leimkuhler C, Chen L, Walker D, Kahne D, Walker S. Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. Journal of Bacteriology. 187: 2215-7. PMID 15743972 DOI: 10.1128/Jb.187.6.2215-2217.2005  0.623
2005 Kahne D, Leimkuhler C, Lu W, Walsh C. Glycopeptide and lipoglycopeptide antibiotics Chemical Reviews. 105: 425-448. PMID 15700951 DOI: 10.1021/Cr030103A  0.537
2005 Leimkuhler C, Chen Z, Kruger RG, Oberthür M, Lu W, Walsh CT, Kahne D. Glycosylation of glycopeptides: A comparison of chemoenzymatic and chemical methods Tetrahedron Asymmetry. 16: 599-603. DOI: 10.1016/J.Tetasy.2004.12.006  0.565
2004 Oberthür M, Leimkuhler C, Kahne D. A practical method for the stereoselective generation of β-2-deoxy glycosyl phosphates Organic Letters. 6: 2873-2876. PMID 15330636 DOI: 10.1021/Ol049187F  0.542
2004 Lu W, Leimkuhler C, Oberthür M, Kahne D, Walsh CT. AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A. Biochemistry. 43: 4548-58. PMID 15078101 DOI: 10.1021/Bi035945I  0.591
2004 Lu W, Oberthür M, Leimkuhler C, Tao J, Kahne D, Walsh CT. Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin. Proceedings of the National Academy of Sciences of the United States of America. 101: 4390-5. PMID 15070728 DOI: 10.1073/Pnas.0400277101  0.621
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