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Sean A. McKenna, Ph.D. - Publications

Affiliations: 
2004 University of Alberta, Edmonton, Alberta, Canada 
Area:
Synthetic Biology, Ubiquitin
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McRae EKS, Davidson DE, McKenna SA. 2D Saturation Transfer Difference NMR for Determination of Protein Binding Sites on RNA Guanine Quadruplexes. Methods in Molecular Biology (Clifton, N.J.). 2161: 101-113. PMID 32681509 DOI: 10.1007/978-1-0716-0680-3_9  0.391
2020 Wu Z, Andersen PL, Moraes T, McKenna SA, Zhang Y, Zhang W, Ellison MJ, Xiao W. Uev1A amino terminus stimulates poly-ubiquitin chain assembly and is required for NF-κB activation. Cellular Signalling. 109712. PMID 32659264 DOI: 10.1016/J.Cellsig.2020.109712  0.733
2020 Koul A, Gemmill D, Lubna N, Meier M, Krahn N, Booy EP, Stetefeld J, Patel TR, McKenna SA. Structural and Hydrodynamic Characterization of Dimeric Human Oligoadenylate Synthetase 2. Biophysical Journal. PMID 32413313 DOI: 10.1016/J.Bpj.2020.04.025  0.672
2019 McRae EKS, Dupas SJ, Booy EP, Piragasam RS, Fahlman RP, McKenna SA. An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21. Rna (New York, N.Y.). PMID 31653714 DOI: 10.1261/Rna.072199.119  0.337
2019 McRae EKS, Nevonen DE, McKenna SA, Nemykin VN. Binding and photodynamic action of the cationic zinc phthalocyanines with different types of DNA toward understanding of their cancer therapy activity. Journal of Inorganic Biochemistry. 199: 110793. PMID 31357069 DOI: 10.1016/J.Jinorgbio.2019.110793  0.34
2019 Koul A, Deo S, Booy EP, Orriss G, Genung M, McKenna SA. Impact of double-stranded RNA characteristics on the activation of human 2'-5'-oligoadenylate synthetase 2 (OAS2). Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 30965010 DOI: 10.1139/Bcb-2019-0060  0.444
2018 Booy EP, McRae EKS, Ezzati P, Choi T, Gussakovsky D, McKenna SA. Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR. Nucleic Acids Research. PMID 30247708 DOI: 10.1093/Nar/Gky860  0.419
2018 McRae EKS, Davidson DE, Dupas SJ, McKenna SA. Insights into the RNA quadruplex binding specificity of DDX21. Biochimica Et Biophysica Acta. PMID 29906500 DOI: 10.1016/J.Bbagen.2018.06.009  0.451
2018 Meier M, Moya-Torres A, Krahn NJ, McDougall MD, Orriss GL, McRae EKS, Booy EP, McEleney K, Patel TR, McKenna SA, Stetefeld J. Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge. Nucleic Acids Research. PMID 29718405 DOI: 10.1093/Nar/Gky307  0.588
2018 Dzananovic E, McKenna SA, Patel TR. Viral proteins targeting host protein kinase R to evade an innate immune response: a mini review. Biotechnology & Genetic Engineering Reviews. 1-27. PMID 29716441 DOI: 10.1080/02648725.2018.1467151  0.628
2017 Krahn N, Meier M, To V, Booy EP, McEleney K, O'Neil JD, McKenna SA, Patel TR, Stetefeld J. Nanoscale Assembly of High-Mobility Group AT-Hook 2 Protein with DNA Replication Fork. Biophysical Journal. 113: 2609-2620. PMID 29262356 DOI: 10.1016/J.Bpj.2017.10.026  0.627
2017 McRae EKS, Booy EP, Padilla-Meier GP, McKenna SA. On Characterizing the Interactions between Proteins and Guanine Quadruplex Structures of Nucleic Acids. Journal of Nucleic Acids. 2017: 9675348. PMID 29250441 DOI: 10.1155/2017/9675348  0.436
2017 Dzananovic E, Astha, Chojnowski G, Deo S, Booy EP, Padilla-Meier P, McEleney K, Bujnicki JM, Patel TR, McKenna SA. Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition. Plos One. 12: e0186849. PMID 29053745 DOI: 10.1371/Journal.Pone.0186849  0.649
2017 Booy EP, McRae EK, Koul A, Lin F, McKenna SA. The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation. Molecular Cancer. 16: 109. PMID 28651607 DOI: 10.1186/S12943-017-0679-7  0.306
2017 McRae EKS, Booy EP, Moya-Torres A, Ezzati P, Stetefeld J, McKenna SA. Human DDX21 binds and unwinds RNA guanine quadruplexes. Nucleic Acids Research. PMID 28472472 DOI: 10.1093/Nar/Gkx380  0.44
2017 Ariyo EO, Booy EP, Dzananovic E, McRae EK, Meier M, McEleney K, Stetefeld J, McKenna SA. Impact of G-quadruplex loop conformation in the PITX1 mRNA on protein and small molecule interaction. Biochemical and Biophysical Research Communications. PMID 28412358 DOI: 10.1016/J.Bbrc.2017.04.049  0.363
2017 McKenna SA, Koch M, Bujnicki JM, Stetefeld J, Patel TR. Studying Biomolecular Interactions: A Hybrid Approach Biophysical Journal. 112: 485a. DOI: 10.1016/J.Bpj.2016.11.2626  0.542
2016 Stetefeld J, McKenna SA, Patel TR. Dynamic light scattering: a practical guide and applications in biomedical sciences. Biophysical Reviews. 8: 409-427. PMID 28510011 DOI: 10.1007/S12551-016-0218-6  0.577
2016 Patel TR, Chojnowski G, Astha, Koul A, McKenna SA, Bujnicki JM. Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods. Methods (San Diego, Calif.). PMID 27939506 DOI: 10.1016/J.Ymeth.2016.12.002  0.628
2016 Jeng SC, Chan HH, Booy EP, McKenna SA, Unrau PJ. Fluorophore ligand binding and complex stabilization of the RNA Mango and RNA Spinach aptamers. Rna (New York, N.Y.). PMID 27777365 DOI: 10.1261/Rna.056226.116  0.38
2016 To V, Dzananovic E, McKenna SA, O'Neil JD. The Dynamic Landscape of Full-Length HIV-1 Transactivator of Transcription. Biochemistry. PMID 26866386 DOI: 10.1021/Acs.Biochem.5B01178  0.396
2016 Booy EP, McRae EK, Howard R, Deo SR, Ariyo EO, Dzananovic E, Meier M, Stetefeld J, McKenna SA. The RNA Helicase RHAU (DHX36) Interacts with the 3' tail of the Long Non-coding RNA BC200 (BCYRN1). The Journal of Biological Chemistry. PMID 26740632 DOI: 10.1074/Jbc.M115.711499  0.411
2015 Ariyo EO, Booy EP, Patel TR, Dzananovic E, McRae EK, Meier M, McEleney K, Stetefeld J, McKenna SA. Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU. Plos One. 10: e0144510. PMID 26649896 DOI: 10.1371/Journal.Pone.0144510  0.643
2015 Deo S, Patel TR, Chojnowski G, Koul A, Dzananovic E, McEleney K, Bujnicki JM, McKenna SA. Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2' 5'-oligoadenylate synthetase family. Journal of Structural Biology. 190: 236-49. PMID 25871524 DOI: 10.1016/J.Jsb.2015.04.005  0.657
2015 Booy EP, McRae EK, McKenna SA. Biochemical characterization of G4 quadruplex telomerase RNA unwinding by the RNA helicase RHAU. Methods in Molecular Biology (Clifton, N.J.). 1259: 125-35. PMID 25579584 DOI: 10.1007/978-1-4939-2214-7_9  0.411
2014 Deo S, Patel TR, Dzananovic E, Booy EP, Zeid K, McEleney K, Harding SE, McKenna SA. Activation of 2' 5'-oligoadenylate synthetase by stem loops at the 5'-end of the West Nile virus genome. Plos One. 9: e92545. PMID 24651762 DOI: 10.1371/Journal.Pone.0092545  0.652
2014 Booy EP, Howard R, Marushchak O, Ariyo EO, Meier M, Novakowski SK, Deo SR, Dzananovic E, Stetefeld J, McKenna SA. The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1. Nucleic Acids Research. 42: 3346-61. PMID 24369427 DOI: 10.1093/Nar/Gkt1340  0.405
2014 Bacik JP, Tavassoli M, Patel TR, McKenna SA, Vocadlo DJ, Khajehpour M, Mark BL. Conformational itinerary of Pseudomonas aeruginosa 1,6-anhydro-N-acetylmuramic acid kinase during its catalytic cycle. The Journal of Biological Chemistry. 289: 4504-14. PMID 24362022 DOI: 10.1074/Jbc.M113.521633  0.633
2014 Dzananovic E, Patel TR, Chojnowski G, Boniecki MJ, Deo S, McEleney K, Harding SE, Bujnicki JM, McKenna SA. Solution conformation of adenovirus virus associated RNA-I and its interaction with PKR. Journal of Structural Biology. 185: 48-57. PMID 24291322 DOI: 10.1016/J.Jsb.2013.11.007  0.644
2013 Meier M, Patel TR, Booy EP, Marushchak O, Okun N, Deo S, Howard R, McEleney K, Harding SE, Stetefeld J, McKenna SA. Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU). The Journal of Biological Chemistry. 288: 35014-27. PMID 24151078 DOI: 10.1074/Jbc.M113.512970  0.659
2013 Dzananovic E, Patel TR, Deo S, McEleney K, Stetefeld J, McKenna SA. Recognition of viral RNA stem-loops by the tandem double-stranded RNA binding domains of PKR. Rna (New York, N.Y.). 19: 333-44. PMID 23329698 DOI: 10.1261/Rna.035931.112  0.676
2012 Booy EP, Meng H, McKenna SA. Native RNA purification by gel filtration chromatography. Methods in Molecular Biology (Clifton, N.J.). 941: 69-81. PMID 23065554 DOI: 10.1007/978-1-62703-113-4_6  0.38
2012 Meng H, Deo S, Xiong S, Dzananovic E, Donald LJ, van Dijk CW, McKenna SA. Regulation of the interferon-inducible 2'-5'-oligoadenylate synthetases by adenovirus VA(I) RNA. Journal of Molecular Biology. 422: 635-49. PMID 22709583 DOI: 10.1016/J.Jmb.2012.06.017  0.461
2012 Booy EP, Meier M, Okun N, Novakowski SK, Xiong S, Stetefeld J, McKenna SA. The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary. Nucleic Acids Research. 40: 4110-24. PMID 22238380 DOI: 10.1093/Nar/Gkr1306  0.438
2012 Meier M, Xiong S, Okun N, Patel TR, Booy E, Donald L, McKenna S, Stetefeld J. G4 Quadruplex Recognition in the Human DEAH-Box Helicase RHAU Biophysical Journal. 102: 486a. DOI: 10.1016/J.Bpj.2011.11.2664  0.626
2009 Elazar M, Liu M, McKenna SA, Liu P, Gehrig EA, Puglisi JD, Rossignol JF, Glenn JS. The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation. Gastroenterology. 137: 1827-35. PMID 19664635 DOI: 10.1053/J.Gastro.2009.07.056  0.328
2009 Shimoike T, McKenna SA, Lindhout DA, Puglisi JD. Translational insensitivity to potent activation of PKR by HCV IRES RNA. Antiviral Research. 83: 228-37. PMID 19467267 DOI: 10.1016/J.Antiviral.2009.05.004  0.361
2007 McKenna SA, Kim I, Puglisi EV, Lindhout DA, Aitken CE, Marshall RA, Puglisi JD. Purification and characterization of transcribed RNAs using gel filtration chromatography. Nature Protocols. 2: 3270-7. PMID 18079727 DOI: 10.1038/Nprot.2007.480  0.358
2007 McKenna SA, Lindhout DA, Shimoike T, Puglisi JD. Biophysical and biochemical investigations of dsRNA-activated kinase PKR. Methods in Enzymology. 430: 373-96. PMID 17913645 DOI: 10.1016/S0076-6879(07)30014-1  0.409
2007 McKenna SA, Lindhout DA, Shimoike T, Aitken CE, Puglisi JD. Viral dsRNA inhibitors prevent self-association and autophosphorylation of PKR. Journal of Molecular Biology. 372: 103-13. PMID 17619024 DOI: 10.1016/J.Jmb.2007.06.028  0.436
2007 McKenna SA, Lindhout DA, Kim I, Liu CW, Gelev VM, Wagner G, Puglisi JD. Molecular framework for the activation of RNA-dependent protein kinase. The Journal of Biological Chemistry. 282: 11474-86. PMID 17284445 DOI: 10.1074/Jbc.M700301200  0.439
2007 Kim I, McKenna SA, Viani Puglisi E, Puglisi JD. Rapid purification of RNAs using fast performance liquid chromatography (FPLC). Rna (New York, N.Y.). 13: 289-94. PMID 17179067 DOI: 10.1261/Rna.342607  0.354
2006 McKenna SA, Kim I, Liu CW, Puglisi JD. Uncoupling of RNA binding and PKR kinase activation by viral inhibitor RNAs. Journal of Molecular Biology. 358: 1270-85. PMID 16580685 DOI: 10.1016/J.Jmb.2006.03.003  0.44
2005 Ptak C, Varelas X, Moraes T, McKenna S, Ellison MJ. Purification and properties of the ubiquitin-conjugating enzymes Cdc34 and Ubc13.Mms2. Methods in Enzymology. 398: 43-54. PMID 16275318 DOI: 10.1016/S0076-6879(05)98005-1  0.713
2005 Andersen PL, Zhou H, Pastushok L, Moraes T, McKenna S, Ziola B, Ellison MJ, Dixit VM, Xiao W. Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A. The Journal of Cell Biology. 170: 745-55. PMID 16129784 DOI: 10.1083/Jcb.200502113  0.736
2003 McKenna S, Hu J, Moraes T, Xiao W, Ellison MJ, Spyracopoulos L. Energetics and specificity of interactions within Ub.Uev.Ubc13 human ubiquitin conjugation complexes. Biochemistry. 42: 7922-30. PMID 12834344 DOI: 10.1021/Bi034480T  0.749
2003 McKenna S, Moraes T, Pastushok L, Ptak C, Xiao W, Spyracopoulos L, Ellison MJ. An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis. The Journal of Biological Chemistry. 278: 13151-8. PMID 12569095 DOI: 10.1074/Jbc.M212353200  0.752
2002 Ashley C, Pastushok L, McKenna S, Ellison MJ, Xiao W. Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination. Gene. 285: 183-91. PMID 12039045 DOI: 10.1016/S0378-1119(02)00409-2  0.633
2001 Hamilton KS, Ellison MJ, Barber KR, Williams RS, Huzil JT, McKenna S, Ptak C, Glover M, Shaw GS. Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail. Structure (London, England : 1993). 9: 897-904. PMID 11591345 DOI: 10.1016/S0969-2126(01)00657-8  0.749
2001 McKenna S, Spyracopoulos L, Moraes T, Pastushok L, Ptak C, Xiao W, Ellison MJ. Noncovalent Interaction between Ubiquitin and the Human DNA Repair Protein Mms2 Is Required for Ubc13-mediated Polyubiquitination Journal of Biological Chemistry. 276: 40120-40126. PMID 11504715 DOI: 10.1074/Jbc.M102858200  0.751
2001 Moraes TF, Edwards RA, McKenna S, Pastushok L, Xiao W, Glover JN, Ellison MJ. Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13. Nature Structural Biology. 8: 669-73. PMID 11473255 DOI: 10.1038/90373  0.743
2001 Barrette IH, McKenna S, Taylor DR, Forsdyke DR. Introns resolve the conflict between base order-dependent stem-loop potential and the encoding of RNA or protein: further evidence from overlapping genes. Gene. 270: 181-9. PMID 11404015 DOI: 10.1016/S0378-1119(01)00477-2  0.35
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