David Gonzalez, Ph.D. - Publications

Affiliations: 
2011 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Biochemistry, Chemical Biology, Mass spectrometry; Harvesting genomic information for therapeutics

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gonzalez CG, Stevens TW, Verstockt B, Gonzalez DJ, D'Haens G, Dulai PS. Crohn's Patient Serum Proteomics Reveals Response Signature for Infliximab but not Vedolizumab. Inflammatory Bowel Diseases. PMID 38367209 DOI: 10.1093/ibd/izae016  0.373
2024 Fallon TR, Shende VV, Wierzbicki IH, Auber RP, Gonzalez DJ, Wisecaver JH, Moore BS. Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin. Biorxiv : the Preprint Server For Biology. PMID 38352448 DOI: 10.1101/2024.01.29.577497  0.782
2024 Buzun E, Hsu CY, Sejane K, Oles RE, Vasquez Ayala A, Loomis LR, Zhao J, Rossitto LA, McGrosso DM, Gonzalez DJ, Bode L, Chu H. A bacterial sialidase mediates early-life colonization by a pioneering gut commensal. Cell Host & Microbe. PMID 38228143 DOI: 10.1016/j.chom.2023.12.014  0.774
2023 Buzun E, Hsu CY, Sejane K, Oles RE, Ayala AV, Loomis LR, Zhao J, Rossitto LA, McGrosso D, Gonzalez DJ, Bode L, Chu H. A bacterial sialidase mediates early life colonization by a pioneering gut commensal. Biorxiv : the Preprint Server For Biology. PMID 37609270 DOI: 10.1101/2023.08.08.552477  0.777
2023 Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, ... ... Gonzalez DJ, et al. Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metabolism. PMID 37084733 DOI: 10.1016/j.cmet.2023.03.021  0.761
2023 Patel A, McGrosso D, Hefner Y, Campeau A, Sastry AV, Maurya S, Rychel K, Gonzalez DJ, Palsson BO. Proteome allocation is linked to transcriptional regulation through a modularized transcriptome. Biorxiv : the Preprint Server For Biology. PMID 36865326 DOI: 10.1101/2023.02.20.529291  0.784
2022 Hayat O, Ullah N, Sirajuddin M, Giardini MA, Nguyen JV, Francisco KR, Liu LJ, Sun YU, Maurya S, McGrosso D, Gonzalez DJ, Caffrey CR, Debnath A, Siqueira-Neto JL. A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using . Pathogens (Basel, Switzerland). 11. PMID 36558759 DOI: 10.3390/pathogens11121424  0.783
2022 Sauceda C, Bayne C, Sudqi K, Gonzalez A, Dulai PS, Knight R, Gonzalez DJ, Gonzalez CG. Stool multi-omics for the study of host-microbe interactions in inflammatory bowel disease. Gut Microbes. 14: 2154092. PMID 36503356 DOI: 10.1080/19490976.2022.2154092  0.773
2022 Elsaid K, Merriman TR, Rossitto LA, Liu-Bryan R, Karsh J, Phipps-Green A, Jay GD, Elsayed S, Qadri M, Miner M, Cadzow M, Dambruoso TJ, Schmidt T, Dalbeth N, Chhana A, ... ... Gonzalez DJ, et al. Amplification of inflammation by lubricin deficiency implicated in incident, erosive gout independent of hyperuricemia. Arthritis & Rheumatology (Hoboken, N.J.). PMID 36457235 DOI: 10.1002/art.42413  0.755
2022 Lordén G, Wozniak JM, Doré K, Dozier LE, Cates-Gatto C, Patrick GN, Gonzalez DJ, Roberts AJ, Tanzi RE, Newton AC. Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model. Nature Communications. 13: 7200. PMID 36418293 DOI: 10.1038/s41467-022-34679-7  0.538
2022 Pilo CA, Baffi TR, Kornev AP, Kunkel MT, Malfavon M, Chen DH, Rossitto LA, Chen DX, Huang LC, Longman C, Kannan N, Raskind WH, Gonzalez DJ, Taylor SS, Gorrie G, et al. Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition. Science Signaling. 15: eabk1147. PMID 36166510 DOI: 10.1126/scisignal.abk1147  0.773
2022 Gonzalez CG, Mills RH, Zhu Q, Sauceda C, Knight R, Dulai PS, Gonzalez DJ. Location-specific signatures of Crohn's disease at a multi-omics scale. Microbiome. 10: 133. PMID 35999575 DOI: 10.1186/s40168-022-01331-x  0.775
2022 Russell BJ, Brown SD, Siguenza N, Mai I, Saran AR, Lingaraju A, Maissy ES, Dantas Machado AC, Pinto AFM, Sanchez C, Rossitto LA, Miyamoto Y, Richter RA, Ho SB, Eckmann L, ... ... Gonzalez DJ, et al. Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes. Cell. PMID 35931082 DOI: 10.1016/j.cell.2022.06.050  0.78
2022 Geriak M, McGrosso D, Gonzalez DJ, Dehner M, Sakoulas G. Case Series of Successful Intravenous Immunoglobulin (IVIG) Treatment in 4 Pregnant Patients with Severe COVID-19-Induced Hypoxia. The American Journal of Case Reports. 23: e936734. PMID 35567293 DOI: 10.12659/AJCR.936734  0.758
2022 Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H, Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM, Delaroque C, Sauceda C, Rossitto LA, ... ... Gonzalez DJ, et al. The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients. Cellular and Molecular Gastroenterology and Hepatology. PMID 35378331 DOI: 10.1016/j.jcmgh.2022.03.008  0.762
2022 Molinar-Inglis O, Wozniak JM, Grimsey NJ, Orduña-Castillo L, Cheng N, Lin Y, Gonzalez Ramirez ML, Birch CA, Lapek JD, Gonzalez DJ, Trejo J. Phosphoproteomic analysis of thrombin- and p38 MAPK-regulated signaling networks in endothelial cells. The Journal of Biological Chemistry. 101801. PMID 35257745 DOI: 10.1016/j.jbc.2022.101801  0.749
2022 Mills RH, Dulai PS, Vázquez-Baeza Y, Sauceda C, Daniel N, Gerner RR, Batachari LE, Malfavon M, Zhu Q, Weldon K, Humphrey G, Carrillo-Terrazas M, Goldasich LD, Bryant M, Raffatellu M, ... ... Gonzalez DJ, et al. Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity. Nature Microbiology. PMID 35087228 DOI: 10.1038/s41564-021-01050-3  0.789
2022 Oom AL, Stoneham CA, Lewinski MK, Richards A, Wozniak JM, Shams-Ud-Doha K, Gonzalez DJ, Krogan NJ, Guatelli J. Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression. Molecular & Cellular Proteomics : McP. 100194. PMID 35017099 DOI: 10.1016/j.mcpro.2022.100194  0.556
2021 Stoneham CA, Langer S, De Jesus PD, Wozniak JM, Lapek J, Deerinck T, Thor A, Pache L, Chanda SK, Gonzalez DJ, Ellisman M, Guatelli J. A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor. Plos Pathogens. 17: e1009409. PMID 34843601 DOI: 10.1371/journal.ppat.1009409  0.753
2021 Campeau A, Mills RH, Stevens T, Rossitto LA, Meehan M, Dorrestein P, Daly R, Nguyen TT, Gonzalez DJ, Jeste DV, Hook V. Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia. Molecular Psychiatry. PMID 34741130 DOI: 10.1038/s41380-021-01339-z  0.755
2021 Campeau A, Uchiyama S, Sanchez C, Sauceda C, Nizet V, Gonzalez DJ. The S Protein of Group B Is a Critical Virulence Determinant That Impacts the Cell Surface Virulome. Frontiers in Microbiology. 12: 729308. PMID 34721327 DOI: 10.3389/fmicb.2021.729308  0.781
2021 O'Neill AM, Worthing KA, Kulkarni N, Li F, Nakatsuji T, McGrosso D, Mills RH, Kalla G, Cheng JY, Norris JM, Pogliano K, Pogliano J, Gonzalez DJ, Gallo RL. Antimicrobials from a feline commensal bacterium inhibit skin infection by drug-resistant . Elife. 10. PMID 34664551 DOI: 10.7554/eLife.66793  0.787
2021 Wu ZY, Campeau A, Liu CH, Gonzalez DJ, Yamaguchi M, Kawabata S, Lu CH, Lai CY, Chiu HC, Chang YC. Unique virulence role of post-translocational chaperone PrsA in shaping secretome. Virulence. 12: 2633-2647. PMID 34592883 DOI: 10.1080/21505594.2021.1982501  0.792
2021 Rada CC, Mejia-Pena H, Grimsey NJ, Canto Cordova I, Olson J, Wozniak JM, Gonzalez DJ, Nizet V, Trejo J. Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption. Science Signaling. 14: eabc1044. PMID 34516752 DOI: 10.1126/scisignal.abc1044  0.601
2021 Wedegaertner H, Pan WA, Gonzalez CC, Gonzalez DJ, Trejo J. The α-arrestin ARRDC3 is an Emerging Multifunctional Adaptor Protein in Cancer. Antioxidants & Redox Signaling. PMID 34465145 DOI: 10.1089/ars.2021.0193  0.355
2021 Kaulich M, Link VM, Lapek JD, Lee YJ, Glass CK, Gonzalez DJ, Dowdy SF. A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition. Scientific Reports. 11: 14736. PMID 34282211 DOI: 10.1038/s41598-021-94200-w  0.651
2021 Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, et al. mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science Signaling. 14. PMID 33850054 DOI: 10.1126/scisignal.abe4509  0.524
2021 Aubol BE, Wozniak JM, Fattet L, Gonzalez DJ, Adams JA. CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33811140 DOI: 10.1073/pnas.2018251118  0.529
2021 Awdishu L, Le A, Amato J, Jani V, Bal S, Mills RH, Carrillo-Terrazas M, Gonzalez DJ, Tolwani A, Acharya A, Cerda J, Joy MS, Nicoletti P, Macedo E, Vaingankar S, et al. Urinary Exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury. International Journal of Molecular Sciences. 22. PMID 33801801 DOI: 10.3390/ijms22062784  0.536
2021 Takahashi M, Lio CJ, Campeau A, Steger M, Ay F, Mann M, Gonzalez DJ, Jain M, Sharma S. The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway. Nature Immunology. PMID 33767426 DOI: 10.1038/s41590-021-00896-3  0.707
2021 Agelidis A, Suryawanshi RK, Patil CD, Campeau A, Gonzalez DJ, Shukla D. Dissociation of DNA damage sensing by endoglycosidase HPSE. Iscience. 24: 102242. PMID 33748723 DOI: 10.1016/j.isci.2021.102242  0.714
2021 Agelidis A, Turturice BA, Suryawanshi RK, Yadavalli T, Jaishankar D, Ames J, Hopkins J, Koujah L, Patil CD, Hadigal SR, Kyzar EJ, Campeau A, Wozniak JM, Gonzalez DJ, Vlodavsky I, et al. Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival. Jci Insight. PMID 33621216 DOI: 10.1172/jci.insight.144255  0.793
2020 Patra KP, Kaur H, Kolli SK, Wozniak JM, Prieto JH, Yates JR, Gonzalez DJ, Janse CJ, Vinetz JM. A Hetero-Multimeric Chitinase-Containing and Ookinete-Secreted Protein Complex Involved in Mosquito Midgut Invasion. Frontiers in Cellular and Infection Microbiology. 10: 615343. PMID 33489941 DOI: 10.3389/fcimb.2020.615343  0.573
2020 Vrbanac A, Patras KA, Jarmusch AK, Mills RH, Shing SR, Quinn RA, Vargas F, Gonzalez DJ, Dorrestein PC, Knight R, Nizet V. Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic. Msystems. 5. PMID 33024048 DOI: 10.1128/mSystems.00340-20  0.787
2020 Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 182: 1311-1327.e14. PMID 32888495 DOI: 10.1016/J.Cell.2020.07.040  0.78
2020 Ramirez-Sanchez I, Navarrete-Yañez V, Garate-Carrillo A, Loredo M, Lira-Romero E, Estrada-Mena J, Campeau A, Gonzalez D, Carrillo-Terrazas M, Moreno-Ulloa A, Ceballos G, Villarreal F. Development of muscle atrophy and loss of function in a Gulf-War illness model: underlying mechanisms. Scientific Reports. 10: 14526. PMID 32884027 DOI: 10.1038/S41598-020-71486-W  0.713
2020 Heckmann D, Campeau A, Lloyd CJ, Phaneuf PV, Hefner Y, Carrillo-Terrazas M, Feist AM, Gonzalez DJ, Palsson BO. Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873645 DOI: 10.1073/Pnas.2001562117  0.718
2020 Campeau A, Mills RH, Blanchette M, Bajc K, Malfavon M, Munji RN, Deng L, Hancock B, Patras KA, Olson J, Nizet V, Daneman R, Doran K, Gonzalez DJ. Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B . Msystems. 5. PMID 32843537 DOI: 10.1128/mSystems.00368-20  0.777
2020 Wozniak JM, Silva TA, Thomas D, Siqueira-Neto JL, McKerrow JH, Gonzalez DJ, Calvet CM. Molecular dissection of chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways. Plos Neglected Tropical Diseases. 14: e0007980. PMID 32433643 DOI: 10.1371/Journal.Pntd.0007980  0.589
2020 Rojony R, Danelishvili L, Campeau A, Wozniak JM, Gonzalez DJ, Bermudez LE. Exposure of to Environmental Stress and Clinically Used Antibiotics Reveals Common Proteome Response among Pathogenic Mycobacteria. Microorganisms. 8. PMID 32397563 DOI: 10.3390/microorganisms8050698  0.787
2020 Lin Y, Wozniak JM, Grimsey NJ, Girada S, Patwardhan A, Molinar-Inglis O, Smith TH, Lapek JD, Gonzalez DJ, Trejo J. Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32071217 DOI: 10.1073/Pnas.1917295117  0.752
2020 Mills RH, Wozniak JM, Vrbanac A, Campeau A, Chassaing B, Gewirtz A, Knight R, Gonzalez DJ. Organ level protein networks as a reference for the host effects of the microbiome. Genome Research. PMID 31992612 DOI: 10.1101/Gr.256875.119  0.788
2020 O'Neill AM, Nakatsuji T, Hayachi A, Williams MR, Mills RH, Gonzalez DJ, Gallo RL. Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes. The Journal of Investigative Dermatology. PMID 31981578 DOI: 10.1016/J.Jid.2019.12.026  0.569
2020 Hernandez GAC, Schnarkowski F, Harel M, Ho K, Campeau A, Sankaran B, Gonzalez D, Fenical W, Taylor P. Targeting the Homomeric α7 Nicotinic Receptor and Acetylcholine Binding Protein with Lophotoxin by X‐ray Crystallography and Mass Spectrometry The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05138  0.711
2020 Lin Y, Wozniak J, Grimsey N, Girada S, Patwardan A, Molinar-Inglis O, Smith T, Lapek J, Gonzalez D, Trejo J. Phospho‐proteomic Analysis of Protease‐activated Receptor‐1 Biased Signaling Reveals Novel Modulators of Endothelial Barrier Function The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04784  0.748
2020 Mills R, Dulai P, Vázquez-Baeza Y, Zhu Q, Humphrey G, DeRight Goldasich L, Quinn R, Gewirtz A, Chassaing B, Chu H, Sandborn W, Dorrestein P, Knight R, Gonzalez D. OP31 Meta–omics reveals microbiome-driven proteolysis as a contributing factor to the severity of ulcerative colitis disease activity Journal of Crohn's and Colitis. 14: S030-S031. DOI: 10.1093/Ecco-Jcc/Jjz203.030  0.69
2019 Wierzbicki IH, Campeau A, Dehaini D, Holay M, Wei X, Greene T, Ying M, Sands JS, Lamsa A, Zuniga E, Pogliano K, Fang RH, LaRock CN, Zhang L, Gonzalez DJ. Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion. Cell Reports. 29: 2979-2989.e15. PMID 31801066 DOI: 10.1016/J.Celrep.2019.11.001  0.779
2019 Rojony R, Martin M, Campeau A, Wozniak JM, Gonzalez DJ, Jaiswal P, Danelishvili L, Bermudez LE. Quantitative analysis of subsp proteome in response to antibiotics and during exposure to different environmental conditions. Clinical Proteomics. 16: 39. PMID 31749666 DOI: 10.1186/S12014-019-9260-2  0.793
2019 Korandla DR, Wozniak JM, Campeau A, Gonzalez DJ, Wright ES. AssessORF: combining evolutionary conservation and proteomics to assess prokaryotic gene predictions. Bioinformatics (Oxford, England). PMID 31532487 DOI: 10.1093/Bioinformatics/Btz714  0.769
2019 Gao NJ, Al-Bassam MM, Poudel S, Wozniak JM, Gonzalez DJ, Olson J, Zengler K, Nizet V, Valderrama JA. Functional and Proteomic Analysis of Virulence Upon Loss of Its Native Cas9 Nuclease. Frontiers in Microbiology. 10: 1967. PMID 31507572 DOI: 10.3389/Fmicb.2019.01967  0.778
2019 Tran HQ, Mills RH, Peters NV, Holder MK, de Vries GJ, Knight R, Chassaing B, Gonzalez DJ, Gewirtz AT. Associations of the fecal microbial proteome composition and proneness to diet-induced obesity. Molecular & Cellular Proteomics : McP. PMID 31262998 DOI: 10.1074/Mcp.Ra119.001623  0.525
2019 Wozniak JM, Gonzalez DJ. : an R package for PTM site localization and motif extraction from proteomic datasets. Peerj. 7: e7046. PMID 31198645 DOI: 10.7717/peerj.7046  0.563
2019 Wei X, Ran D, Campeau A, Xiao C, Zhou J, Dehaini D, Jiang Y, Kroll AV, Zhang Q, Gao W, Gonzalez DJ, Fang RH, Zhang L. Multiantigenic Nanotoxoids for Antivirulence Vaccination against Antibiotic-Resistant Gram-Negative Bacteria. Nano Letters. PMID 31184899 DOI: 10.1021/Acs.Nanolett.9B01844  0.72
2019 Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nature Cell Biology. PMID 31110287 DOI: 10.1038/S41556-019-0330-5  0.583
2019 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Dragicevic M, Erö J, Escalante Del Valle A, Flechl M, Frühwirth R, Ghete VM, Hrubec J, Jeitler M, ... Gonzalez D, et al. Observation of Single Top Quark Production in Association with a Z Boson in Proton-Proton Collisions at sqrt[s]=13  TeV. Physical Review Letters. 122: 132003. PMID 31012605 DOI: 10.1103/Physrevlett.122.132003  0.309
2019 Mills RH, Vázquez-Baeza Y, Zhu Q, Jiang L, Gaffney J, Humphrey G, Smarr L, Knight R, Gonzalez DJ. Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn's Disease. Msystems. 4. PMID 30801026 DOI: 10.1128/mSystems.00337-18  0.591
2019 Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, et al. Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome. Microbiome. 7: 23. PMID 30760325 DOI: 10.1186/S40168-019-0636-3  0.611
2019 Lapek JD, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry. Molecular & Cellular Proteomics : McP. PMID 30705125 DOI: 10.1074/mcp.TIR118.001099  0.756
2019 Breuer M, Earnest TM, Merryman C, Wise KS, Sun L, Lynott MR, Hutchison CA, Smith HO, Lapek JD, Gonzalez DJ, de Crécy-Lagard V, Haas D, Hanson AD, Labhsetwar P, Glass JI, et al. Essential metabolism for a minimal cell. Elife. 8. PMID 30657448 DOI: 10.7554/Elife.36842  0.672
2018 Solomon T, Lapek JD, Jensen SB, Greenwald WW, Hindberg K, Matsui H, Latysheva N, Braekken SK, Gonzalez DJ, Frazer KA, Smith EN, Hansen JB. Identification of Common and Rare Genetic Variation Associated With Plasma Protein Levels Using Whole-Exome Sequencing and Mass Spectrometry. Circulation. Genomic and Precision Medicine. 11: e002170. PMID 30562114 DOI: 10.1161/CIRCGEN.118.002170  0.665
2018 Al-Bassam MM, Kim JN, Zaramela LS, Kellman BP, Zuniga C, Wozniak JM, Gonzalez DJ, Zengler K. Optimization of carbon and energy utilization through differential translational efficiency. Nature Communications. 9: 4474. PMID 30367068 DOI: 10.1038/S41467-018-06993-6  0.536
2018 Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, et al. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer. Cell. 175: 679-694.e22. PMID 30340040 DOI: 10.1016/J.Cell.2018.09.004  0.637
2018 Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Correction to: Mitochondrial H-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. PMID 30324489 DOI: 10.1007/s00125-018-4747-3  0.631
2018 Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Reports. 24: 3312-3323.e5. PMID 30232011 DOI: 10.1016/J.Celrep.2018.08.061  0.659
2018 Jensen SB, Hindberg K, Solomon T, Smith EN, Lapek JD, Gonzalez DJ, Latysheva N, Frazer KA, Braekkan SK, Hansen JB. Discovery of novel plasma biomarkers for future incident venous thromboembolism by untargeted synchronous precursor selection mass spectrometry proteomics. Journal of Thrombosis and Haemostasis : Jth. PMID 29964323 DOI: 10.1111/jth.14220  0.651
2018 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Dragicevic M, Erö J, Escalante Del Valle A, Flechl M, Frühwirth R, Ghete VM, Hrubec J, Jeitler M, ... Gonzalez D, et al. Observation of tt[over ¯]H Production. Physical Review Letters. 120: 231801. PMID 29932697 DOI: 10.1103/Physrevlett.120.231801  0.304
2018 Wang H, Lapek J, Fujimura K, Strnadel J, Liu B, Gonzalez DJ, Zhang W, Watson F, Yu V, Liu C, Melo CM, Miller YI, Elliott KC, Cheresh DA, Klemke RL. Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. Cell Discovery. 4: 26. PMID 29872538 DOI: 10.1038/S41421-018-0024-3  0.661
2018 Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. The Journal of Infectious Diseases. PMID 29868829 DOI: 10.1093/Infdis/Jiy341  0.792
2018 Lapek JD, Mills RH, Wozniak JM, Campeau A, Fang RH, Wei X, van de Groep K, Perez-Lopez A, van Sorge NM, Raffatellu M, Knight R, Zhang L, Gonzalez DJ. Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas. Cell Systems. PMID 29778837 DOI: 10.1016/J.Cels.2018.04.010  0.784
2018 Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M. Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology. 9: 262. PMID 29515544 DOI: 10.3389/Fmicb.2018.00262  0.776
2018 Perera VR, Lapek JD, Newton GL, Gonzalez DJ, Pogliano K. Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis. Plos One. 13: e0192977. PMID 29451913 DOI: 10.1371/Journal.Pone.0192977  0.677
2018 Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, et al. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 172: 590-604.e13. PMID 29373831 DOI: 10.1016/J.Cell.2017.12.032  0.566
2018 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Grossmann J, ... Gonzalez D, et al. Search for top squarks and dark matter particles in opposite-charge dilepton final states at s = 13 TeV Physical Review D. 97: 32009. DOI: 10.1103/Physrevd.97.032009  0.3
2018 Sirunyan A, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete V, Grossmann J, ... Gonzalez D, et al. Search for gauge-mediated supersymmetry in events with at least one photon and missing transverse momentum in pp collisions at s=13TeV Physics Letters B. 780: 118-143. DOI: 10.1016/J.Physletb.2018.02.045  0.307
2018 Grainger S, Wozniak J, Gonzalez D, Willert K, Traver D. Specific Wnt-Fzd Interactions are Required for Hematopoietic Stem Cell Development Experimental Hematology. 64: S68. DOI: 10.1016/J.Exphem.2018.06.234  0.559
2018 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Grossmann J, ... Gonzalez D, et al. Search for supersymmetry in events with at least three electrons or muons, jets, and missing transverse momentum in proton-proton collisions at sqrt(s)=13 TeV Journal of High Energy Physics. 2018: 1-46. DOI: 10.1007/Jhep02(2018)067  0.3
2018 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Grossmann J, ... Gonzalez D, et al. Search for low mass vector resonances decaying into quark-antiquark pairs in proton-proton collisions at $ \sqrt{s}=13 $ TeV Journal of High Energy Physics. 2018: 97. DOI: 10.1007/Jhep01(2018)097  0.303
2017 Lapek JD, Fang RH, Wei X, Li P, Wang B, Zhang L, Gonzalez DJ. Biomimetic Virulomics for Capture and Identification of Cell-Type Specific Effector Proteins. Acs Nano. PMID 28892626 DOI: 10.1021/Acsnano.7B02650  0.687
2017 Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon JE, Kranias EG. Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784772 DOI: 10.1073/Pnas.1706441114  0.394
2017 Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Mitochondrial H(+)-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. PMID 28770317 DOI: 10.1007/s00125-017-4379-z  0.642
2017 Lapek JD, Lewinski MK, Wozniak JM, Guatelli J, Gonzalez DJ. Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Vpr. Molecular & Cellular Proteomics : McP. PMID 28606917 DOI: 10.1074/Mcp.M116.066019  0.754
2017 Sirunyan A, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Bondu O, Ahmad A, Ahmad M, Hassan Q, ... Gonzalez D, et al. Search for supersymmetry in multijet events with missing transverse momentum in proton-proton collisions at 13 TeV Physical Review D. 96: 32003. DOI: 10.1103/Physrevd.96.032003  0.301
2017 Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Ero J, Flechl M, Friedl M, Fruhwirth R, Ghete VM, Hartl C, ... Gonzalez D, et al. Search for supersymmetry in the all-hadronic final state using top quark tagging in pp collisions at s=13 TeV Physical Review D. 96: 1-32. DOI: 10.1103/Physrevd.96.012004  0.306
2017 Khachatryan V, Sirunyan A, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete V, Hartl C, ... Gonzalez D, et al. Search for heavy gauge W′ bosons in events with an energetic lepton and large missing transverse momentum at s=13 TeV Physics Letters B. 770: 278-301. DOI: 10.1016/J.Physletb.2017.04.043  0.301
2017 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Ero J, Flechl M, Friedl M, Fruhwirth R, Ghete VM, Grossmann J, ... Gonzalez D, et al. Search for direct production of supersymmetric partners of the top quark in the all-jets final state in proton-proton collisions at √s=13 TeV Journal of High Energy Physics. 2017: 5. DOI: 10.1007/Jhep10(2017)005  0.305
2016 Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Gonzalez DJ, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/Nbt.3597  0.765
2016 Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, ... Gonzalez D, et al. Search for new physics with the M T2 variable in all-jets final states produced in pp collisions at √ s=13 TeV Journal of High Energy Physics. 2016: 1-60. DOI: 10.1007/Jhep10(2016)006  0.302
2016 Sirunyan AM, Tumasyan A, Adam W, Ambrogi F, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Grossmann J, ... Gonzalez D, et al. Search for Supersymmetry in pp Collisions at √s = 13 TeV in the Single-Lepton Final State Using the Sum of Masses of Large-Radius Jets Physical Review Letters. 119: 122. DOI: 10.1007/Jhep08(2016)122  0.304
2016 Khachatryan, Sirunyan A, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Ero J, Flechl M, Friedl M, Fruhwirth R, Ghete V, Hartl C, ... Gonzalez D, et al. Search for the associated production of a Higgs boson with a single top quark in proton-proton collisions at √s = 8 TeV Journal of High Energy Physics. 2016: 177. DOI: 10.1007/Jhep06(2016)177  0.304
2016 Khachatryan V, Erbacher R, Montoya CAC, Carvalho W, Górski M, Kotlinski D, Jez P, Ujvari B, Bein S, Lander R, Smith N, Choi Y, Hadjiiska R, Bartek R, Lath A, ... Gonzalez D, et al. Search for electroweak production of charginos in final states with two tau leptons in pp collisions at sqrt(s) = 8 TeV Journal of High Energy Physics. 1704: 18. DOI: 10.1007/Jhep04(2017)018  0.304
2015 Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V. Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. Nature Communications. 6: 8369. PMID 26458291 DOI: 10.1038/Ncomms9369  0.787
2014 Gonzalez DJ, Corriden R, Akong-Moore K, Olson J, Dorrestein PC, Nizet V. N-terminal ArgD peptides from the classical Staphylococcus aureus Agr system have cytotoxic and proinflammatory activities. Chemistry & Biology. 21: 1457-62. PMID 25457179 DOI: 10.1016/J.Chembiol.2014.09.015  0.779
2014 Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 111: 5520-5. PMID 24706917 DOI: 10.1073/Pnas.1402218111  0.767
2014 Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Molecular & Cellular Proteomics : McP. 13: 1262-72. PMID 24567418 DOI: 10.1074/Mcp.M113.031336  0.79
2014 Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proceedings of the National Academy of Sciences of the United States of America. 111: 1957-62. PMID 24449899 DOI: 10.1073/Pnas.1319584111  0.756
2013 Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: E4407-16. PMID 24191063 DOI: 10.1073/Pnas.1315492110  0.761
2013 van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V. Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development. The Journal of Biological Chemistry. 288: 6417-26. PMID 23322784 DOI: 10.1074/Jbc.M112.448738  0.786
2012 Hollands A, Gonzalez D, Leire E, Donald C, Gallo RL, Sanderson-Smith M, Dorrestein PC, Nizet V. A bacterial pathogen co-opts host plasmin to resist killing by cathelicidin antimicrobial peptides. The Journal of Biological Chemistry. 287: 40891-7. PMID 23038245 DOI: 10.1074/Jbc.M112.404582  0.787
2012 Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen PR, Fischbach M, Liaw CC, Straight P, Nizet V, et al. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. Journal of Proteomics. 75: 5069-76. PMID 22641157 DOI: 10.1016/J.Jprot.2012.05.036  0.783
2012 Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. The Journal of Biological Chemistry. 287: 13889-98. PMID 22371493 DOI: 10.1074/Jbc.M112.349860  0.776
2011 Gonzalez DJ, Haste NM, Hollands A, Fleming TC, Hamby M, Pogliano K, Nizet V, Dorrestein PC. Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometry. Microbiology (Reading, England). 157: 2485-92. PMID 21719540 DOI: 10.1099/Mic.0.048736-0  0.792
2011 Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, ... Gonzalez D, et al. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Applied and Environmental Microbiology. 77: 3617-25. PMID 21498757 DOI: 10.1128/Aem.00038-11  0.79
2010 Liu WT, Yang YL, Xu Y, Lamsa A, Haste NM, Yang JY, Ng J, Gonzalez D, Ellermeier CD, Straight PD, Pevzner PA, Pogliano J, Nizet V, Pogliano K, Dorrestein PC. Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 107: 16286-90. PMID 20805502 DOI: 10.1073/Pnas.1008368107  0.797
2010 Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. The Journal of Biological Chemistry. 285: 28220-8. PMID 20581111 DOI: 10.1074/Jbc.M110.118554  0.782
2010 He C, Nora GP, Schneider EL, Kerr ID, Hansell E, Hirata K, Gonzalez D, Sajid M, Boyd SE, Hruz P, Cobo ER, Le C, Liu WT, Eckmann L, Dorrestein PC, et al. A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target. The Journal of Biological Chemistry. 285: 18516-27. PMID 20378535 DOI: 10.1074/Jbc.M109.086181  0.613
2009 Jones AC, Gerwick L, Gonzalez D, Dorrestein PC, Gerwick WH. Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins. Bmc Microbiology. 9: 247. PMID 19951434 DOI: 10.1186/1471-2180-9-247  0.49
2008 Esquenazi E, Coates C, Simmons L, Gonzalez D, Gerwick WH, Dorrestein PC. Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. Molecular Biosystems. 4: 562-70. PMID 18493654 DOI: 10.1039/B720018H  0.752
2008 Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 105: 5879-84. PMID 18375757 DOI: 10.1073/Pnas.0801338105  0.781
2008 Simmons TL, Coates RC, Clark BR, Engene N, Gonzalez D, Esquenazi E, Dorrestein PC, Gerwick WH. Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages. Proceedings of the National Academy of Sciences of the United States of America. 105: 4587-94. PMID 18250337 DOI: 10.1073/Pnas.0709851105  0.758
2007 González D, van der Burg M, García-Sanz R, Fenton JA, Langerak AW, González M, van Dongen JJ, San Miguel JF, Morgan GJ. Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma. Blood. 110: 3112-21. PMID 17634408 DOI: 10.1182/Blood-2007-02-069625  0.311
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