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Giselle M. Knudsen, Ph.D. - Publications

Affiliations: 
2003 University of California, San Francisco, San Francisco, CA 
Area:
protein structure, mechanism, and inhibitor design
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20/229 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu C, Knudsen GM, Pedley AM, He J, Johnson JL, Yaron TM, Cantley LC, Benkovic SJ. Mapping post-translational modifications of de novo purine biosynthetic enzymes: Implications for pathway regulation. Journal of Proteome Research. PMID 30964683 DOI: 10.1021/Acs.Jproteome.8B00969  0.327
2018 Beekman C, Jiang Z, Suzuki BM, Palmer JM, Lindner DL, O'Donoghue AJ, Knudsen GM, Bennett RJ. Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome. Biological Chemistry. PMID 30367778 DOI: 10.1515/Hsz-2018-0240  0.356
2017 Ivry SL, Meyer NO, Winter MB, Bohn MF, Knudsen GM, O'Donoghue AJ, Craik CS. Global substrate specificity profiling of post-translational modifying enzymes. Protein Science : a Publication of the Protein Society. PMID 29168252 DOI: 10.1002/Pro.3352  0.325
2017 Meyer NO, O'Donoghue AJ, Schulze-Gahmen U, Ravalin M, Moss SM, Winter MB, Knudsen GM, Craik CS. Multiplex Substrate Profiling by Mass Spectrometry for Kinases Reveals Quantitative Substrate Motifs. Analytical Chemistry. PMID 28322550 DOI: 10.1021/Acs.Analchem.6B05002  0.318
2016 Julien O, Zhuang M, Wiita AP, O'Donoghue AJ, Knudsen GM, Craik CS, Wells JA. Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles. Proceedings of the National Academy of Sciences of the United States of America. PMID 27006500 DOI: 10.1073/Pnas.1524900113  0.322
2015 Soupene E, Kao J, Cheng DH, Wang D, Greninger AL, Knudsen GM, DeRisi JL, Kuypers FA. Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA. Journal of Lipid Research. PMID 26621918 DOI: 10.1194/Jlr.M065003  0.336
2015 O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik CS, Bennett RJ. Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 7478-83. PMID 25944934 DOI: 10.1073/Pnas.1507082112  0.344
2013 O'Donoghue AJ, Jin Y, Knudsen GM, Perera NC, Jenne DE, Murphy JE, Craik CS, Hermiston TW. Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase. Plos One. 8: e75141. PMID 24073241 DOI: 10.1371/Journal.Pone.0075141  0.358
2013 Greninger AL, Knudsen GM, Betegon M, Burlingame AL, DeRisi JL. ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding. Mbio. 4: e00098-13. PMID 23572552 DOI: 10.1128/Mbio.00098-13  0.32
2013 Small JL, O'Donoghue AJ, Boritsch EC, Tsodikov OV, Knudsen GM, Vandal O, Craik CS, Ehrt S. Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 288: 12489-99. PMID 23504313 DOI: 10.1074/Jbc.M113.456541  0.372
2013 Sanchez LM, Knudsen GM, Helbig C, De Muylder G, Mascuch SM, Mackey ZB, Gerwick L, Clayton C, McKerrow JH, Linington RG. Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of Natural Products. 76: 630-41. PMID 23445522 DOI: 10.1021/Np300834Q  0.303
2012 O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS. Global identification of peptidase specificity by multiplex substrate profiling. Nature Methods. 9: 1095-100. PMID 23023596 DOI: 10.1038/Nmeth.2182  0.341
2012 Sojka D, Franta Z, Frantová H, Bartosová P, Horn M, Váchová J, O'Donoghue AJ, Eroy-Reveles AA, Craik CS, Knudsen GM, Caffrey CR, McKerrow JH, Mares M, Kopácek P. Characterization of gut-associated cathepsin D hemoglobinase from tick Ixodes ricinus (IrCD1). The Journal of Biological Chemistry. 287: 21152-63. PMID 22539347 DOI: 10.1074/Jbc.M112.347922  0.339
2008 Dvorák J, Mashiyama ST, Braschi S, Sajid M, Knudsen GM, Hansell E, Lim KC, Hsieh I, Bahgat M, Mackenzie B, Medzihradszky KF, Babbitt PC, Caffrey CR, McKerrow JH. Differential use of protease families for invasion by schistosome cercariae. Biochimie. 90: 345-58. PMID 17936488 DOI: 10.1016/J.Biochi.2007.08.013  0.323
2005 Knudsen GM, Medzihradszky KF, Lim KC, Hansell E, McKerrow JH. Proteomic analysis of Schistosoma mansoni cercarial secretions. Molecular & Cellular Proteomics : McP. 4: 1862-75. PMID 16112986 DOI: 10.1074/Mcp.M500097-Mcp200  0.302
2005 Ghiladi RA, Knudsen GM, Medzihradszky KF, Ortiz de Montellano PR. The Met-Tyr-Trp cross-link in Mycobacterium tuberculosis catalase-peroxidase (KatG): autocatalytic formation and effect on enzyme catalysis and spectroscopic properties. The Journal of Biological Chemistry. 280: 22651-63. PMID 15840564 DOI: 10.1074/Jbc.M502486200  0.619
2004 Koshkin A, Knudsen GM, Ortiz De Montellano PR. Intermolecular interactions in the AhpC/AhpD antioxidant defense system of Mycobacterium tuberculosis. Archives of Biochemistry and Biophysics. 427: 41-7. PMID 15178486 DOI: 10.1016/J.Abb.2004.04.017  0.525
2003 Knudsen GM, Nishida CR, Mooney SD, Ortiz de Montellano PR. Nitric-oxide synthase (NOS) reductase domain models suggest a new control element in endothelial NOS that attenuates calmodulin-dependent activity. The Journal of Biological Chemistry. 278: 31814-24. PMID 12805387 DOI: 10.1074/Jbc.M303267200  0.512
2002 Nishida CR, Knudsen G, Straub W, Ortiz de Montellano PR. Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase. Drug Metabolism Reviews. 34: 479-501. PMID 12214661 DOI: 10.1081/Dmr-120005648  0.509
1999 Rodríguez-Crespo I, Nishida CR, Knudsen GM, Ortiz De Montellano PR. Mutation of the five conserved histidines in the endothelial nitric- oxide synthase hemoprotein domain. No evidence for a non-heme metal requirement for catalysis Journal of Biological Chemistry. 274: 21617-21624. PMID 10419469 DOI: 10.1074/Jbc.274.31.21617  0.508
Low-probability matches (unlikely to be authored by this person)
2010 Swenerton RK, Knudsen GM, Sajid M, Kelly BL, McKerrow JH. Leishmania subtilisin is a maturase for the trypanothione reductase system and contributes to disease pathology. The Journal of Biological Chemistry. 285: 31120-9. PMID 20675366 DOI: 10.1074/Jbc.M110.114462  0.295
2016 Valenciano AL, Knudsen GM, Mackey ZB. Extracellular-signal Regulated Kinase 8 of Trypanosoma brucei Uniquely Phosphorylates its Proliferating Cell Nuclear Antigen Homolog and Reveals Exploitable Properties. Cell Cycle (Georgetown, Tex.). 0. PMID 27589575 DOI: 10.1080/15384101.2016.1222340  0.294
2014 Ishida K, Varrecchia M, Knudsen GM, Jolly ER. Immunolocalization of anti-hsf1 to the acetabular glands of infectious schistosomes suggests a non-transcriptional function for this transcriptional activator. Plos Neglected Tropical Diseases. 8: e3051. PMID 25078989 DOI: 10.1371/Journal.Pntd.0003051  0.293
2013 Bessat M, Knudsen G, Burlingame AL, Wang CC. A minimal anaphase promoting complex/cyclosome (APC/C) in Trypanosoma brucei. Plos One. 8: e59258. PMID 23533609 DOI: 10.1371/Journal.Pone.0059258  0.288
2016 Greene TT, Tokuyama M, Knudsen GM, Kunz M, Lin J, Greninger AL, DeFilippis VR, DeRisi JL, Raulet DH, Coscoy L. A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression. Elife. 5. PMID 27874833 DOI: 10.7554/Elife.14749  0.286
2012 Greninger AL, Knudsen GM, Betegon M, Burlingame AL, Derisi JL. The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ. Journal of Virology. 86: 3605-16. PMID 22258260 DOI: 10.1128/Jvi.06778-11  0.283
2014 Morris JH, Knudsen GM, Verschueren E, Johnson JR, Cimermancic P, Greninger AL, Pico AR. Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions. Nature Protocols. 9: 2539-54. PMID 25275790 DOI: 10.1038/Nprot.2014.164  0.277
2017 Medina GN, Knudsen GM, Greninger AL, Kloc A, Díaz-San Segundo F, Rieder E, Grubman MJ, DeRisi JL, de Los Santos T. Interaction between FMDV L(pro) and transcription factor ADNP is required for optimal viral replication. Virology. 505: 12-22. PMID 28219017 DOI: 10.1016/J.Virol.2017.02.010  0.277
2015 Morris M, Knudsen GM, Maeda S, Trinidad JC, Ioanoviciu A, Burlingame AL, Mucke L. Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice. Nature Neuroscience. 18: 1183-9. PMID 26192747 DOI: 10.1038/Nn.4067  0.262
2019 Ivry SL, Knudsen GM, Caiazza F, Sharib JM, Jaradeh K, Ravalin M, O'Donoghue AJ, Kirkwood KS, Craik CS. The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts. Biological Chemistry. PMID 31256057 DOI: 10.1515/Hsz-2019-0103  0.259
2011 Knudsen GM, Chalkley RJ. The effect of using an inappropriate protein database for proteomic data analysis. Plos One. 6: e20873. PMID 21695130 DOI: 10.1371/Journal.Pone.0020873  0.258
2011 Ingram J, Knudsen G, Lim KC, Hansell E, Sakanari J, McKerrow J. Proteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukes. Plos Neglected Tropical Diseases. 5: e1337. PMID 21980548 DOI: 10.1371/Journal.Pntd.0001337  0.257
2015 Bulman CA, Bidlow CM, Lustigman S, Cho-Ngwa F, Williams D, Rascón AA, Tricoche N, Samje M, Bell A, Suzuki B, Lim KC, Supakorndej N, Supakorndej P, Wolfe AR, Knudsen GM, et al. Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis. Plos Neglected Tropical Diseases. 9: e0003534. PMID 25700363 DOI: 10.1371/Journal.Pntd.0003534  0.238
2008 Deb SK, Davis B, Knudsen GM, Gudihal R, Ben-Amotz D, Davisson VJ. Detection and relative quantification of proteins by surface enhanced Raman using isotopic labels. Journal of the American Chemical Society. 130: 9624-5. PMID 18593116 DOI: 10.1021/Ja800772P  0.236
2019 Mandel-Brehm C, Retallack H, Knudsen GM, Yamana A, Hajj-Ali RA, Calabrese LH, Tihan T, Sample HA, Zorn KC, Gorman MP, Madan Cohen J, Sreih AG, Marcus JF, Josephson SA, Douglas VC, et al. Exploratory proteomic analysis implicates the alternative complement cascade in primary CNS vasculitis. Neurology. PMID 31270218 DOI: 10.1212/Wnl.0000000000007850  0.229
2008 Loethen YL, Knudsen GM, Davis B, Gudihal R, Davisson VJ, Ben-Amotz D. Protein quantitation in 2-D gels using fluorescence with water Raman as an internal standard. Journal of Proteome Research. 7: 1341-5. PMID 18088088 DOI: 10.1021/Pr0704579  0.226
2016 Greene TT, Tokuyama M, Knudsen GM, Kunz M, Lin J, Greninger AL, DeFilippis VR, DeRisi JL, Raulet DH, Coscoy L. Author response: A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression Elife. DOI: 10.7554/Elife.14749.026  0.219
2018 Greninger AL, Knudsen GM, Roychoudhury P, Hanson DJ, Sedlak RH, Xie H, Guan J, Nguyen T, Peddu V, Boeckh M, Huang ML, Cook L, Depledge DP, Zerr DM, Koelle DM, et al. Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6. Bmc Genomics. 19: 204. PMID 29554870 DOI: 10.1186/S12864-018-4604-2  0.214
2013 Thai K, Khan M, Nicolls M, Ray D, Nelson T, Fu C, Patel S, Gong D, Odegaard J, Knudsen G, Hsieh M. 1146 CHRONIC INFLAMMATION-INDUCED HEMATURIA INVOLVES MOLECULAR MODULATION OF THE UROTHELIAL BARRIER AND BLADDER VASCULATURE Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.781  0.212
2013 Bessat M, Knudsen G, Burlingame AL, Wang CC. Correction: A Minimal Anaphase Promoting Complex/Cyclosome (APC/C) in Trypanosoma brucei Plos One. 8. DOI: 10.1371/Annotation/D048Ae1B-6A9B-4353-Bdf2-C707925Ce37C  0.203
2024 Pourmal S, Green E, Bajaj R, Chemmama IE, Knudsen GM, Gupta M, Sali A, Cheng Y, Craik CS, Kroetz DL, Stroud RM. Structural basis of prostaglandin efflux by MRP4. Nature Structural & Molecular Biology. PMID 38216659 DOI: 10.1038/s41594-023-01176-4  0.168
2012 Feld L, Knudsen GM, Gram L. Bactericidal antibiotics do not appear to cause oxidative stress in Listeria monocytogenes. Applied and Environmental Microbiology. 78: 4353-7. PMID 22504823 DOI: 10.1128/AEM.00324-12  0.149
2010 Kramer V, Herth MM, Santini MA, Palner M, Knudsen GM, Rösch F. Structural combination of established 5-HT2A receptor ligands: New aspects of the binding mode Chemical Biology and Drug Design. 76: 361-366. PMID 20636331 DOI: 10.1111/j.1747-0285.2010.01011.x  0.148
2021 Salcedo EC, Winter MB, Khuri N, Knudsen GM, Sali A, Craik CS. Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer. Acs Chemical Biology. PMID 33765766 DOI: 10.1021/acschembio.0c01000  0.143
2016 da Cunha-Bang S, Hjordt LV, Perfalk E, Beliveau V, Bock C, Lehel S, Thomsen C, Sestoft D, Svarer C, Knudsen GM. Serotonin 1B Receptor Binding Is Associated With Trait Anger and Level of Psychopathy in Violent Offenders Biological Psychiatry. DOI: 10.1016/j.biopsych.2016.02.030  0.142
2010 Wellendorph P, Høg S, Sabbatini P, Pedersen MHF, Martiny L, Knudsen GM, Frølund B, Clausen RP, Bräuner-Osborne H. Novel radioiodinated γ-hydroxybutyric acid analogues for radiolabeling and photolinking of high-affinity γ-hydroxybutyric acid binding sites Journal of Pharmacology and Experimental Therapeutics. 335: 458-464. PMID 20696866 DOI: 10.1124/Jpet.110.170670  0.141
2013 Macoveanu J, Hornboll B, Elliott R, Erritzoe D, Paulson OB, Siebner H, Knudsen GM, Rowe JB. Serotonin 2A receptors, citalopram and tryptophan-depletion: a multimodal imaging study of their interactions during response inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 996-1005. PMID 23303045 DOI: 10.1038/Npp.2012.264  0.135
2015 Stenbæk DS, Einarsdottir HS, Goregliad-Fjaellingsdal T, Knudsen GM, Frokjaer VG, Hasselbalch SG. Evaluation of acute tryptophan depletion and sham depletion with a gelatin-based collagen peptide protein mixture. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26655163 DOI: 10.1016/j.euroneuro.2015.11.010  0.13
2023 Sampognaro PJ, Arya S, Knudsen GM, Gunderson EL, Sandoval-Perez A, Hodul M, Bowles K, Craik CS, Jacobson MP, Kao AW. Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases. Molecular Neurodegeneration. 18: 29. PMID 37131250 DOI: 10.1186/s13024-023-00621-8  0.13
2013 Knudsen GM, Olsen JE, Aabo S, Barrow P, Rychlik I, Thomsen LE. ClpP deletion causes attenuation of Salmonella Typhimurium virulence through mis-regulation of RpoS and indirect control of CsrA and the SPI genes. Microbiology (Reading, England). 159: 1497-509. PMID 23676436 DOI: 10.1099/mic.0.065797-0  0.127
2012 Clemmensen C, Aznar S, Knudsen GM, Klein AB. The microtubule-associated protein 1A (MAP1A) is an early molecular target of soluble Aβ-peptide. Cellular and Molecular Neurobiology. 32: 561-6. PMID 22252785 DOI: 10.1007/s10571-011-9796-9  0.127
2012 Absalom N, Eghorn LF, Villumsen IS, Karim N, Bay T, Olsen JV, Knudsen GM, Bräuner-Osborne H, Frølund B, Clausen RP, Chebib M, Wellendorph P. α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB). Proceedings of the National Academy of Sciences of the United States of America. 109: 13404-9. PMID 22753476 DOI: 10.1073/Pnas.1204376109  0.126
2008 Knudsen GM, Davis BM, Deb SK, Loethen Y, Gudihal R, Perera P, Ben-Amotz D, Davisson VJ. Quantification of isotope encoded proteins in 2-D gels using surface enhanced resonance Raman. Bioconjugate Chemistry. 19: 2212-20. PMID 18925772 DOI: 10.1021/Bc800325K  0.124
2010 Marner L, Gillings N, Madsen K, Erritzoe D, Baaré WFC, Svarer C, Hasselbalch SG, Knudsen GM. Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET Neuroimage. 50: 855-861. PMID 20096787 DOI: 10.1016/j.neuroimage.2010.01.054  0.123
2015 Fisher PM, Haahr ME, Jensen CG, Frokjaer VG, Siebner HR, Knudsen GM. Fluctuations in [¹¹C]SB207145 PET binding associated with change in threat-related amygdala reactivity in humans. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1510-8. PMID 25560201 DOI: 10.1038/npp.2014.339  0.121
2016 Jakobsen GR, Fisher PM, Dyssegaard A, McMahon B, Holst KK, Lehel S, Svarer C, Jensen PS, Knudsen GM, Frokjaer VG. Brain serotonin 4 receptor binding is associated with the cortisol awakening response. Psychoneuroendocrinology. 67: 124-132. PMID 26894483 DOI: 10.1016/j.psyneuen.2016.01.032  0.118
2011 Ettrup A, Mikkelsen JD, Lehel S, Madsen J, Nielsen E, Palner M, Timmermann DB, Peters D, Knudsen GM. 11C-NS14492 as a novel PET radioligand for imaging cerebral α7 nicotinic acetylcholine receptors: In vivo evaluation and drug occupancy measurements Journal of Nuclear Medicine. 52: 1449-1456. PMID 21828113 DOI: 10.2967/jnumed.111.088815  0.116
2012 Fisher PM, Holst KK, Mc Mahon B, Haahr ME, Madsen K, Gillings N, Baaré WF, Jensen PS, Knudsen GM. 5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [(11)C]SB207145 PET in humans. Neuroimage. 62: 130-6. PMID 22584237 DOI: 10.1016/j.neuroimage.2012.05.013  0.115
2009 Syvänen S, Lindhe O, Palner M, Kornum BR, Rahman O, Långström B, Knudsen GM, Hammarlund-Udenaes M. Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport Drug Metabolism and Disposition. 37: 635-643. PMID 19047468 DOI: 10.1124/dmd.108.024745  0.114
2015 Fisher PM, Holst KK, Adamsen D, Klein AB, Frokjaer VG, Jensen PS, Svarer C, Gillings N, Baare WF, Mikkelsen JD, Knudsen GM. BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Human Brain Mapping. 36: 313-23. PMID 25220079 DOI: 10.1002/hbm.22630  0.114
2015 Visser AK, Ettrup A, Klein AB, van Waarde A, Bosker FJ, Meerlo P, Knudsen GM, de Boer SF. Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression. Synapse (New York, N.Y.). 69: 226-32. PMID 25684736 DOI: 10.1002/syn.21810  0.113
2009 Kalbitzer J, Frokjaer VG, Erritzoe D, Svarer C, Cumming P, Nielsen FA, Hashemi SH, Baaré WF, Madsen J, Hasselbalch SG, Kringelbach ML, Mortensen EL, Knudsen GM. The personality trait openness is related to cerebral 5-HTT levels. Neuroimage. 45: 280-5. PMID 19135154 DOI: 10.1016/J.Neuroimage.2008.12.001  0.113
2013 Jørgensen CV, Jacobsen JP, Caron MG, Klein AB, Knudsen GM, Mikkelsen JD. Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neuroscience Letters. 555: 118-22. PMID 24055299 DOI: 10.1016/j.neulet.2013.08.073  0.113
2012 Knudsen GM, Nielsen MB, Grassby T, Danino-Appleton V, Thomsen LE, Colquhoun IJ, Brocklehurst TF, Olsen JE, Hinton JC. A third mode of surface-associated growth: immobilization of Salmonella enterica serovar Typhimurium modulates the RpoS-directed transcriptional programme. Environmental Microbiology. 14: 1855-75. PMID 22356617 DOI: 10.1111/j.1462-2920.2012.02703.x  0.111
2011 Ettrup A, Hansen M, Santini MA, Paine J, Gillings N, Palner M, Lehel S, Herth MM, Madsen J, Kristensen J, Begtrup M, Knudsen GM. Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers European Journal of Nuclear Medicine and Molecular Imaging. 38: 681-693. PMID 21174090 DOI: 10.1007/s00259-010-1686-8  0.109
2010 Paulson OB, Hasselbalch SG, Rostrup E, Knudsen GM, Pelligrino D. Cerebral blood flow response to functional activation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 2-14. PMID 19738630 DOI: 10.1038/Jcbfm.2009.188  0.107
2011 Palner M, Underwood MD, Kumar DJ, Arango V, Knudsen GM, John Mann J, Parsey RV. Ex vivo evaluation of the serotonin 1A receptor partial agonist [³H]CUMI-101 in awake rats. Synapse (New York, N.Y.). 65: 715-23. PMID 21108237 DOI: 10.1002/Syn.20888  0.105
2010 Ettrup A, Palner M, Gillings N, Santini MA, Hansen M, Kornum BR, Rasmussen LK, Någren K, Madsen J, Begtrup M, Knudsen GM. Radiosynthesis and evaluation of11C-CIMBI-5 as a 5-HT 2A receptor agonist radioligand for PET Journal of Nuclear Medicine. 51: 1763-1770. PMID 20956470 DOI: 10.2967/jnumed.109.074021  0.105
2011 Santini MA, Klein AB, El-Sayed M, Ratner C, Knudsen GM, Mikkelsen JD, Aznar S. Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation Neuroscience. 190: 251-257. PMID 21664256 DOI: 10.1016/j.neuroscience.2011.05.048  0.105
2015 Morris M, Knudsen GM, Maeda S, Trinidad JC, Ioanoviciu A, Burlingame AL, Mucke L. Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice Nature Neuroscience. 18: 1183-1189. DOI: 10.1038/nn.4067  0.104
2011 Erritzoe D, Frokjaer VG, Holst KK, Christoffersen M, Johansen SS, Svarer C, Madsen J, Rasmussen PM, Ramsøy T, Jernigan TL, Knudsen GM. In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users. Archives of General Psychiatry. 68: 562-76. PMID 21646575 DOI: 10.1001/Archgenpsychiatry.2011.56  0.102
2010 Rasmussen H, Erritzoe D, Andersen R, Ebdrup BH, Aggernaes B, Oranje B, Kalbitzer J, Madsen J, Pinborg LH, Baaré W, Svarer C, Lublin H, Knudsen GM, Glenthoj B. Decreased frontal serotonin2A receptor binding in antipsychotic-naive patients with first-episode schizophrenia Archives of General Psychiatry. 67: 9-16. PMID 20048218 DOI: 10.1001/archgenpsychiatry.2009.176  0.102
2009 Kornum BR, Lind NM, Gillings N, Marner L, Andersen F, Knudsen GM. Evaluation of the novel 5-HT4 receptor PET ligand [ 11C]SB207145 in the Göttingen minipig Journal of Cerebral Blood Flow and Metabolism. 29: 186-196. PMID 18797470 DOI: 10.1038/jcbfm.2008.110  0.102
2014 Feng L, Svarer C, Thomsen G, de Nijs R, Larsen VA, Jensen P, Adamsen D, Dyssegaard A, Fischer W, Meden P, Krieger D, Møller K, Knudsen GM, Pinborg LH. In vivo quantification of cerebral translocator protein binding in humans using 6-chloro-2-(4'-123I-iodophenyl)-3-(N,N-diethyl)-imidazo[1,2-a]pyridine-3-acetamide SPECT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1966-72. PMID 25453044 DOI: 10.2967/jnumed.114.143727  0.101
2009 Trajkovska V, Kirkegaard L, Krey G, Marcussen AB, Thomsen MS, Chourbaji S, Brandwein C, Ridder S, Halldin C, Gass P, Knudsen GM, Aznar S. Activation of glucocorticoid receptors increases 5-HT2A receptor levels. Experimental Neurology. 218: 83-91. PMID 19379741 DOI: 10.1016/J.Expneurol.2009.04.008  0.101
2015 Nalla AA, Thomsen G, Knudsen GM, Frokjaer VG. The effect of storage conditions on salivary cortisol concentrations using an enzyme immunoassay. Scandinavian Journal of Clinical and Laboratory Investigation. 75: 92-5. PMID 25510953 DOI: 10.3109/00365513.2014.985252  0.101
2015 Knudsen GM, Jensen PS, Erritzoe D, Baaré WF, Ettrup A, Fisher PM, Gillings N, Hansen HD, Hansen LK, Hasselbalch SG, Henningsson S, Herth MM, Holst KK, Iversen P, Kessing LV, et al. The Center for Integrated Molecular Brain Imaging (Cimbi) database. Neuroimage. PMID 25891375 DOI: 10.1016/J.Neuroimage.2015.04.025  0.101
2009 Herth MM, Kramer V, Piel M, Palner M, Riss PJ, Knudsen GM, Rösch F. Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET Bioorganic and Medicinal Chemistry. 17: 2989-3002. PMID 19329329 DOI: 10.1016/j.bmc.2009.03.021  0.1
2012 Marner L, Frokjaer VG, Kalbitzer J, Lehel S, Madsen K, Baaré WFC, Knudsen GM, Hasselbalch SG. Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: A combined [ 11C]DASB and [ 18F]altanserin-PET study Neurobiology of Aging. 33: 479-487. PMID 20510480 DOI: 10.1016/j.neurobiolaging.2010.03.023  0.1
2012 Pinborg LH, Feng L, Haahr ME, Gillings N, Dyssegaard A, Madsen J, Svarer C, Yndgaard S, Kjaer TW, Parsey RV, Hansen HD, Ettrup A, Paulson OB, Knudsen GM. No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human. Synapse (New York, N.Y.). 66: 880-4. PMID 22730164 DOI: 10.1002/Syn.21579  0.099
2014 Finnema SJ, Stepanov V, Ettrup A, Nakao R, Amini N, Svedberg M, Lehmann C, Hansen M, Knudsen GM, Halldin C. Characterization of [(11)C]Cimbi-36 as an agonist PET radioligand for the 5-HT(2A) and 5-HT(2C) receptors in the nonhuman primate brain. Neuroimage. 84: 342-53. PMID 23994452 DOI: 10.1016/J.Neuroimage.2013.08.035  0.099
2013 Kalbitzer J, Kalbitzer U, Knudsen GM, Cumming P, Heinz A. How the cerebral serotonin homeostasis predicts environmental changes: a model to explain seasonal changes of brain 5-HTT as intermediate phenotype of the 5-HTTLPR. Psychopharmacology. 230: 333-43. PMID 24150247 DOI: 10.1007/S00213-013-3308-1  0.099
2010 Kornum BR, Stott SR, Mattsson B, Wisman L, Ettrup A, Hermening S, Knudsen GM, Kirik D. Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain. Experimental Neurology. 222: 70-85. PMID 20025873 DOI: 10.1016/J.Expneurol.2009.12.009  0.099
2009 Marner L, Gillings N, Comley RA, Baaré WFC, Rabiner EA, Wilson AA, Houle S, Hasselbalch SG, Svarer C, Gunn RN, Laruelle M, Knudsen GM. Kinetic modeling of11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo Journal of Nuclear Medicine. 50: 900-908. PMID 19470850 DOI: 10.2967/jnumed.108.058552  0.098
2009 Kalbitzer J, Svarer C, Frokjaer VG, Erritzoe D, Baaré WFC, Madsen J, Hasselbalch SG, Knudsen GM. A probabilistic approach to delineating functional brain regions Journal of Nuclear Medicine Technology. 37: 91-95. PMID 19447857 DOI: 10.2967/jnmt.108.054056  0.095
2010 Palner M, McCormick P, Gillings N, Begtrup M, Wilson AA, Knudsen GM. Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine Nuclear Medicine and Biology. 37: 35-40. PMID 20122666 DOI: 10.1016/j.nucmedbio.2009.08.005  0.095
2010 Kalbitzer J, Erritzoe D, Holst KK, Nielsen FA, Marner L, Lehel S, Arentzen T, Jernigan TL, Knudsen GM. Seasonal changes in brain serotonin transporter binding in short serotonin transporter linked polymorphic region-allele carriers but not in long-allele homozygotes. Biological Psychiatry. 67: 1033-9. PMID 20110086 DOI: 10.1016/J.Biopsych.2009.11.027  0.093
2012 Jennings KA, Licht CL, Bruce A, Lesch KP, Knudsen GM, Sharp T. Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HTâ‚„ receptor levels. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1099-107. PMID 21846421 DOI: 10.1017/S1461145711001258  0.092
2010 Frokjaer VG, Erritzoe D, Juul A, Nielsen FA, Holst K, Svarer C, Madsen J, Paulson OB, Knudsen GM. Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding. Psychoneuroendocrinology. 35: 1311-20. PMID 20356681 DOI: 10.1016/J.Psyneuen.2010.03.002  0.092
2010 Bowden SD, Ramachandran VK, Knudsen GM, Hinton JC, Thompson A. An incomplete TCA cycle increases survival of Salmonella Typhimurium during infection of resting and activated murine macrophages. Plos One. 5: e13871. PMID 21079785 DOI: 10.1371/journal.pone.0013871  0.092
2013 Frokjaer VG, Erritzoe D, Holst KK, Jensen PS, Rasmussen PM, Fisher PM, Baaré W, Madsen KS, Madsen J, Svarer C, Knudsen GM. Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 285-94. PMID 22732516 DOI: 10.1016/j.euroneuro.2012.05.013  0.091
2011 Madsen J, Elfving B, Frokjaer VG, Kornum BR, Thomsen G, Martiny L, Knudsen GM. Synthesis and biological evaluation of125I/123I- labelled analogues of citalopram and escitalopram as potential radioligands for imaging of the serotonin transporter Journal of Labelled Compounds and Radiopharmaceuticals. 54: 185-190. DOI: 10.1002/jlcr.1841  0.09
2010 Licht CL, Kirkegaard L, Zueger M, Chourbaji S, Gass P, Aznar S, Knudsen GM. Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice Neurochemistry International. 56: 603-610. PMID 20060867 DOI: 10.1016/j.neuint.2010.01.003  0.09
2013 Rosenkrantz JT, Aarts H, Abee T, Rolfe MD, Knudsen GM, Nielsen MB, Thomsen LE, Zwietering MH, Olsen JE, Pin C. Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium. Bmc Microbiology. 13: 294. PMID 24345035 DOI: 10.1186/1471-2180-13-294  0.089
2014 Ettrup A, da Cunha-Bang S, McMahon B, Lehel S, Dyssegaard A, Skibsted AW, Jørgensen LM, Hansen M, Baandrup AO, Bache S, Svarer C, Kristensen JL, Gillings N, Madsen J, Knudsen GM. Serotonin 2A receptor agonist binding in the human brain with [¹¹C]Cimbi-36. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1188-96. PMID 24780897 DOI: 10.1038/jcbfm.2014.68  0.088
2011 Madsen K, Marner L, Haahr M, Gillings N, Knudsen GM. Mass dose effects and in vivo affinity in brain PET receptor studies - a study of cerebral 5-HT 4 receptor binding with [ 11C]SB207145 Nuclear Medicine and Biology. 38: 1085-1091. PMID 21831646 DOI: 10.1016/j.nucmedbio.2011.04.006  0.088
2011 Marner L, Knudsen GM, Madsen K, Holm S, Baaré W, Hasselbalch SG. The reduction of Baseline serotonin 2A receptors in mild cognitive impairment is stable at two-year follow-up Journal of Alzheimer's Disease. 23: 453-459. PMID 21098981 DOI: 10.3233/Jad-2010-100903  0.087
2011 Palner M, Kjaerby C, Knudsen GM, Cumming P. Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat. Neurochemistry International. 58: 243-7. PMID 21163313 DOI: 10.1016/J.Neuint.2010.12.007  0.087
2023 Sampognaro PJ, Arya S, Knudsen GM, Gunderson EL, Sandoval-Perez A, Hodul M, Bowles K, Craik CS, Jacobson MP, Kao AW. Correction: Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases. Molecular Neurodegeneration. 18: 34. PMID 37254128 DOI: 10.1186/s13024-023-00629-0  0.087
2011 Madsen K, Neumann WJ, Holst K, Marner L, Haahr MT, Lehel S, Knudsen GM, Hasselbalch SG. Cerebral serotonin 4 receptors and amyloid-β in early Alzheimer's disease Journal of Alzheimer's Disease. 26: 457-466. PMID 21673407 DOI: 10.3233/JAD-2011-110056  0.086
2011 Madsen K, Erritzoe D, Mortensen EL, Gade A, Madsen J, Baaré W, Knudsen GM, Hasselbalch SG. Cognitive function is related to fronto-striatal serotonin transporter levels - A brain PET study in young healthy subjects Psychopharmacology. 213: 573-581. PMID 20623110 DOI: 10.1007/s00213-010-1926-4  0.086
2010 Palner M, McCormick P, Parkes J, Knudsen GM, Wilson AA. Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957 Nuclear Medicine and Biology. 37: 837-843. PMID 20870159 DOI: 10.1016/j.nucmedbio.2010.04.193  0.086
2010 Frokjaer VG, Vinberg M, Erritzoe D, Baaré W, Holst KK, Mortensen EL, Arfan H, Madsen J, Jernigan TL, Kessing LV, Knudsen GM. Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1129-37. PMID 20043006 DOI: 10.1038/Npp.2009.218  0.086
2014 Haahr ME, Fisher PM, Jensen CG, Frokjaer VG, Mahon BM, Madsen K, Baaré WF, Lehel S, Norremolle A, Rabiner EA, Knudsen GM. Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C]SB207145 PET study. Molecular Psychiatry. 19: 427-32. PMID 24189342 DOI: 10.1038/Mp.2013.147  0.086
2009 Frokjaer VG, Erritzoe D, Madsen J, Paulson OB, Knudsen GM. Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding. Neuroscience. 163: 640-5. PMID 19559762 DOI: 10.1016/J.Neuroscience.2009.06.052  0.086
2014 Knudsen GM, Hasselbalch SG. Imaging of the serotonin system: Radiotracers and applications in memory disorders Pet and Spect of Neurobiological Systems. 669-686. DOI: 10.1007/978-3-642-42014-6_23  0.085
2009 Licht CL, Marcussen AB, Wegener G, Overstreet DH, Aznar S, Knudsen GM. The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration Journal of Neurochemistry. 109: 1363-1374. PMID 19476548 DOI: 10.1111/j.1471-4159.2009.06050.x  0.085
2010 Klein AB, Santini MA, Aznar S, Knudsen GM, Rios M. Changes in 5-HT2A-mediated behavior and 5-HT2A- and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. Neuroscience. 169: 1007-16. PMID 20576498 DOI: 10.1016/J.Neuroscience.2010.05.054  0.085
2011 Liu X, Cannon DM, Akula N, Moya PR, Knudsen GM, Arentzen TE, Steele J, Laje G, Drevets WC, McMahon FJ. A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study. Molecular Psychiatry. 16: 584-5. PMID 21339755 DOI: 10.1038/mp.2011.1  0.085
2009 Marner L, Knudsen GM, Haugbøl S, Holm S, Baaré W, Hasselbalch SG. Longitudinal assessment of cerebral 5-HT2A receptors in healthy elderly volunteers: An [18F]-altanserin PET study European Journal of Nuclear Medicine and Molecular Imaging. 36: 287-293. PMID 18828013 DOI: 10.1007/s00259-008-0945-4  0.085
2015 Laursen MF, Bahl MI, Licht TR, Gram L, Knudsen GM. A single exposure to a sublethal pediocin concentration initiates a resistance-associated temporal cell envelope and general stress response in Listeria monocytogenes. Environmental Microbiology. 17: 1134-51. PMID 24920558 DOI: 10.1111/1462-2920.12534  0.084
2013 da Cunha-Bang S, Stenbæk DS, Holst K, Licht CL, Jensen PS, Frokjaer VG, Mortensen EL, Knudsen GM. Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals. Psychiatry Research. 212: 125-31. PMID 23137806 DOI: 10.1016/j.pscychresns.2012.09.007  0.084
2010 Erritzoe D, Frokjaer VG, Haahr MT, Kalbitzer J, Svarer C, Holst KK, Hansen DL, Jernigan TL, Lehel S, Knudsen GM. Cerebral serotonin transporter binding is inversely related to body mass index. Neuroimage. 52: 284-9. PMID 20382236 DOI: 10.1016/J.Neuroimage.2010.03.086  0.083
2012 Madsen K, Hasselbalch BJ, Frederiksen KS, Haahr ME, Gade A, Law I, Price JC, Knudsen GM, Kessing LV, Hasselbalch SG. Lack of association between prior depressive episodes and cerebral [11C]PiB binding. Neurobiology of Aging. 33: 2334-42. PMID 22192243 DOI: 10.1016/j.neurobiolaging.2011.11.021  0.083
2009 Frokjaer VG, Vinberg M, Erritzoe D, Svarer C, Baaré W, Budtz-Joergensen E, Madsen K, Madsen J, Kessing LV, Knudsen GM. High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding Neuroimage. 46: 360-366. PMID 19233297 DOI: 10.1016/j.neuroimage.2009.02.008  0.083
2010 Ziebell M, Holm-Hansen S, Thomsen G, Wagner A, Jensen P, Pinborg LH, Knudsen GM. Serotonin transporters in dopamine transporter imaging: A head-to-head comparison of dopamine transporter SPECT radioligands 123I-FP-CIT and 123I-PE2I Journal of Nuclear Medicine. 51: 1885-1891. PMID 21078806 DOI: 10.2967/jnumed.110.078337  0.083
2008 Hasselbalch SG, Madsen K, Svarer C, Pinborg LH, Holm S, Paulson OB, Waldemar G, Knudsen GM. Reduced 5-HT2A receptor binding in patients with mild cognitive impairment. Neurobiology of Aging. 29: 1830-8. PMID 17544547 DOI: 10.1016/J.Neurobiolaging.2007.04.011  0.083
2013 Hornboll B, Macoveanu J, Rowe J, Elliott R, Paulson OB, Siebner HR, Knudsen GM. Acute serotonin 2A receptor blocking alters the processing of fearful faces in the orbitofrontal cortex and amygdala. Journal of Psychopharmacology (Oxford, England). 27: 903-14. PMID 23824248 DOI: 10.1177/0269881113494106  0.082
2012 Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Knudsen GM, Siebner HR, Baaré WF. Hypothalamic-pituitary-adrenal axis tonus is associated with hippocampal microstructural asymmetry. Neuroimage. 63: 95-103. PMID 22776454 DOI: 10.1016/J.Neuroimage.2012.06.071  0.082
2013 Sander CY, Hooker JM, Catana C, Normandin MD, Alpert NM, Knudsen GM, Vanduffel W, Rosen BR, Mandeville JB. Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI. Proceedings of the National Academy of Sciences of the United States of America. 110: 11169-74. PMID 23723346 DOI: 10.1073/Pnas.1220512110  0.082
2013 Knudsen GM, Ng Y, Gram L. Survival of bactericidal antibiotic treatment by a persister subpopulation of Listeria monocytogenes. Applied and Environmental Microbiology. 79: 7390-7. PMID 24056460 DOI: 10.1128/AEM.02184-13  0.081
2014 Knudsen GM, Nielsen MB, Thomsen LE, Aabo S, Rychlik I, Olsen JE. The role of ClpP, RpoS and CsrA in growth and filament formation of Salmonella enterica serovar Typhimurium at low temperature. Bmc Microbiology. 14: 208. PMID 25123657 DOI: 10.1186/s12866-014-0208-4  0.08
2014 Greve DN, Svarer C, Fisher PM, Feng L, Hansen AE, Baare W, Rosen B, Fischl B, Knudsen GM. Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data. Neuroimage. 92: 225-36. PMID 24361666 DOI: 10.1016/j.neuroimage.2013.12.021  0.079
2013 Andersen VL, Herth MM, Lehel S, Knudsen GM, Kristensen JL. Palladium-mediated conversion of para-aminoarylboronic esters into para-aminoaryl-11C-methanes Tetrahedron Letters. 54: 213-216. DOI: 10.1016/j.tetlet.2012.11.001  0.078
2014 Wey HY, Catana C, Hooker JM, Dougherty DD, Knudsen GM, Wang DJ, Chonde DB, Rosen BR, Gollub RL, Kong J. Simultaneous fMRI-PET of the opioidergic pain system in human brain. Neuroimage. 102: 275-82. PMID 25107855 DOI: 10.1016/J.Neuroimage.2014.07.058  0.077
2010 Klein AB, Trajkovska V, Erritzoe D, Haugbol S, Madsen J, Baaré W, Aznar S, Knudsen GM. Cerebral 5-HT 2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels Journal of Cerebral Blood Flow and Metabolism. 30: 1890-1896. DOI: 10.1038/jcbfm.2010.114  0.077
2010 Klein AB, Trajkovska V, Erritzoe D, Haugbol S, Madsen J, Baaré W, Aznar S, Knudsen GM. Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: e1-7. PMID 20736957  0.077
2012 Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Mortensen EL, Knudsen GM, Baaré WF. Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture. Psychiatry Research. 201: 63-72. PMID 22285720 DOI: 10.1016/J.Pscychresns.2011.07.015  0.076
2015 Herth MM, Andersen VL, Hansen HD, Stroth N, Volk B, Lehel S, Dyssegaard A, Ettrup A, Svenningsson P, Knudsen GM, Kristensen JL. Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HT₇ Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs. Journal of Medicinal Chemistry. 58: 3631-6. PMID 25825999 DOI: 10.1021/acs.jmedchem.5b00095  0.076
2016 Ettrup A, Svarer C, McMahon B, da Cunha-Bang S, Lehel S, Møller K, Dyssegaard A, Ganz M, Beliveau V, Jørgensen LM, Gillings N, Knudsen GM. Serotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36: Test-retest reproducibility and head-to-head comparison with the antagonist [18F]altanserin Neuroimage. 130: 167-174. DOI: 10.1016/j.neuroimage.2016.02.001  0.076
2011 Madsen K, Haahr MT, Marner L, Keller SH, Baaré WF, Svarer C, Hasselbalch SG, Knudsen GM. Age and sex effects on 5-HT 4 receptors in the human brain: A 11 CSB207145 PET study Journal of Cerebral Blood Flow and Metabolism. 31: 1475-1481. PMID 21364600 DOI: 10.1038/jcbfm.2011.11  0.075
1995 Knudsen GM, Hasselbalch S, Toft PB, Christensen E, Paulson OB, Lou H. Blood-brain barrier transport of amino acids in healthy controls and in patients with phenylketonuria Journal of Inherited Metabolic Disease. 18: 653-664. PMID 8750601 DOI: 10.1007/Bf02436753  0.075
1999 Kasar RA, Knudsen GM, Kahl SB. Synthesis of 3-Amino-1-carboxy-o-carborane and an Improved, General Method for the Synthesis of All Three C-Amino-C-carboxycarboranes. Inorganic Chemistry. 38: 2936-2940. PMID 11671041  0.074
2014 Macoveanu J, Fisher PM, Haahr ME, Frokjaer VG, Knudsen GM, Siebner HR. Effects of selective serotonin reuptake inhibition on neural activity related to risky decisions and monetary rewards in healthy males. Neuroimage. 99: 434-42. PMID 24857827 DOI: 10.1016/j.neuroimage.2014.05.040  0.074
2015 Frokjaer VG, Pinborg A, Holst KK, Overgaard A, Henningsson S, Heede M, Larsen EC, Jensen PS, Agn M, Nielsen AP, Stenbæk DS, da Cunha-Bang S, Lehel S, Siebner HR, Mikkelsen JD, ... ... Knudsen GM, et al. Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study. Biological Psychiatry. 78: 534-43. PMID 26004162 DOI: 10.1016/j.biopsych.2015.04.015  0.073
2014 Hesse S, van de Giessen E, Zientek F, Petroff D, Winter K, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Darcourt J, Akdemir UO, Knudsen GM, Nobili F, Pagani M, Vander Borght T, et al. Association of central serotonin transporter availability and body mass index in healthy Europeans. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1240-7. PMID 24976619 DOI: 10.1016/J.Euroneuro.2014.05.005  0.072
2013 Paterson LM, Kornum BR, Nutt DJ, Pike VW, Knudsen GM. 5-HT radioligands for human brain imaging with PET and SPECT Medicinal Research Reviews. 33: 54-111. PMID 21674551 DOI: 10.1002/Med.20245  0.072
2011 Ettrup A, Kornum BR, Weikop P, Knudsen GM. An approach for serotonin depletion in pigs: Effects on serotonin receptor binding Synapse. 65: 136-145. PMID 20560131 DOI: 10.1002/syn.20827  0.071
2013 Grady CL, Siebner HR, Hornboll B, Macoveanu J, Paulson OB, Knudsen GM. Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 368-78. PMID 22739125 DOI: 10.1016/J.Euroneuro.2012.06.003  0.071
2012 Knudsen GM, Holch A, Gram L. Subinhibitory concentrations of antibiotics affect stress and virulence gene expression in Listeria monocytogenes and cause enhanced stress sensitivity but do not affect Caco-2 cell invasion. Journal of Applied Microbiology. 113: 1273-86. PMID 22924966 DOI: 10.1111/j.1365-2672.2012.05435.x  0.071
2014 Madsen K, Torstensen E, Holst KK, Haahr ME, Knorr U, Frokjaer VG, Brandt-Larsen M, Iversen P, Fisher PM, Knudsen GM. Familial risk for major depression is associated with lower striatal 5-HT₄ receptor binding. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522384 DOI: 10.1093/ijnp/pyu034  0.071
2010 Ziebell M, Pinborg LH, Thomsen G, de Nijs R, Svarer C, Wagner A, Knudsen GM. MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: A reproducibility study Journal of Nuclear Medicine Technology. 38: 61-68. PMID 20484180 DOI: 10.2967/jnmt.109.072801  0.069
2012 Ziebell M, Khalid U, Klein AB, Aznar S, Thomsen G, Jensen P, Knudsen GM. Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration Neurobiology of Aging. 33: 428.e1-428.e5. PMID 21176997 DOI: 10.1016/j.neurobiolaging.2010.11.010  0.069
2015 Madsen MK, Mc Mahon B, Andersen SB, Siebner HR, Knudsen GM, Fisher PM. Threat-related amygdala functional connectivity is associated with 5-HTTLPR genotype and neuroticism. Social Cognitive and Affective Neuroscience. PMID 26245837 DOI: 10.1093/scan/nsv098  0.068
2014 Klein AB, Ultved L, Adamsen D, Santini MA, Tobeña A, Fernandez-Teruel A, Flores P, Moreno M, Cardona D, Knudsen GM, Aznar S, Mikkelsen JD. 5-HT(2A) and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains. Neuroscience. 263: 36-45. PMID 24412375 DOI: 10.1016/j.neuroscience.2013.12.063  0.068
2013 Varrone A, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Booij J, Kapucu OL, Kluge A, Knudsen GM, Koulibaly PM, Nobili F, Pagani M, Sabri O, Vander Borght T, Van Laere K, et al. European multicentre database of healthy controls for [123I]FP-CIT SPECT (ENC-DAT): age-related effects, gender differences and evaluation of different methods of analysis. European Journal of Nuclear Medicine and Molecular Imaging. 40: 213-27. PMID 23160999 DOI: 10.1007/S00259-012-2276-8  0.068
2013 Risgaard R, Ettrup A, Balle T, Dyssegaard A, Hansen HD, Lehel S, Madsen J, Pedersen H, Püschl A, Badolo L, Bang-Andersen B, Knudsen GM, Kristensen JL. Radiolabelling and PET brain imaging of the α₁-adrenoceptor antagonist Lu AE43936. Nuclear Medicine and Biology. 40: 135-40. PMID 23165140 DOI: 10.1016/j.nucmedbio.2012.09.010  0.068
2011 Jensen PS, Ziebell M, Skouboe G, Khalid U, de Nijs R, Thomsen G, Knudsen GM, Svarer C. Validation of a method for accurate and highly reproducible quantification of brain dopamine transporter SPECT studies Journal of Nuclear Medicine Technology. 39: 271-278. PMID 22072699 DOI: 10.2967/jnmt.111.090324  0.067
2015 Spies M, Knudsen GM, Lanzenberger R, Kasper S. The serotonin transporter in psychiatric disorders: insights from PET imaging. The Lancet. Psychiatry. 2: 743-55. PMID 26249305 DOI: 10.1016/S2215-0366(15)00232-1  0.067
2010 Paterson LM, Tyacke RJ, Nutt DJ, Knudsen GM. Measuring endogenous 5-HT release by emission tomography: Promises and pitfalls Journal of Cerebral Blood Flow and Metabolism. 30: 1682-1706. PMID 20664611 DOI: 10.1038/Jcbfm.2010.104  0.067
2009 Trajkovska V, Santini MA, Marcussen AB, Thomsen MS, Hansen HH, Mikkelsen JD, Arneberg L, Kokaia M, Knudsen GM, Aznar S. BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures. Neurochemistry International. 55: 697-702. PMID 19563850 DOI: 10.1016/j.neuint.2009.06.013  0.067
2011 Kupers R, Frokjaer VG, Erritzoe D, Naert A, Budtz-Joergensen E, Nielsen FA, Kehlet H, Knudsen GM. Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study. Neuroimage. 54: 1336-43. PMID 20851771 DOI: 10.1016/j.neuroimage.2010.09.010  0.067
2009 Erritzoe D, Frokjaer VG, Haugbol S, Marner L, Svarer C, Holst K, Baaré WF, Rasmussen PM, Madsen J, Paulson OB, Knudsen GM. Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. Neuroimage. 46: 23-30. PMID 19457377 DOI: 10.1016/J.Neuroimage.2009.01.050  0.066
2010 Aznar S, Klein AB, Santini MA, Knudsen GM, Henn F, Gass P, Vollmayr B. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness Synapse. 64: 561-565. PMID 20222154 DOI: 10.1002/Syn.20773  0.066
2009 Kupers R, Frokjaer VG, Naert A, Christensen R, Budtz-Joergensen E, Kehlet H, Knudsen GM. A PET [18F]altanserin study of 5-HT2A receptor binding in the human brain and responses to painful heat stimulation. Neuroimage. 44: 1001-7. PMID 19007894 DOI: 10.1016/j.neuroimage.2008.10.011  0.065
2016 Greve DN, Salat DH, Bowen SL, Izquierdo-Garcia D, Schultz AP, Catana C, Becker JA, Svarer C, Knudsen G, Sperling RA, Johnson KA. Different partial volume correction methods lead to different conclusions: An (18)F-FDG-PET study of aging. Neuroimage. PMID 26915497 DOI: 10.1016/J.Neuroimage.2016.02.042  0.065
2015 Haahr ME, Hansen DL, Fisher PM, Svarer C, Stenbæk DS, Madsen K, Madsen J, Holst JJ, Baaré WF, Hojgaard L, Almdal T, Knudsen GM. Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5884-9. PMID 25855196 DOI: 10.1523/JNEUROSCI.3348-14.2015  0.065
2014 Hansen HD, Lacivita E, Di Pilato P, Herth MM, Lehel S, Ettrup A, Andersen VL, Dyssegaard A, De Giorgio P, Perrone R, Berardi F, Colabufo NA, Niso M, Knudsen GM, Leopoldo M. Synthesis, radiolabeling and in vivo evaluation of [(11)C](R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT(7) receptor. European Journal of Medicinal Chemistry. 79: 152-63. PMID 24732791 DOI: 10.1016/j.ejmech.2014.03.066  0.065
2013 Ettrup A, Holm S, Hansen M, Wasim M, Santini MA, Palner M, Madsen J, Svarer C, Kristensen JL, Knudsen GM. Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [ 11C]Cimbi-36. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 376-83. PMID 23306971 DOI: 10.1007/S11307-012-0609-4  0.065
2015 Macoveanu J, Henningsson S, Pinborg A, Jensen P, Knudsen GM, Frokjaer VG, Siebner HR. Sex-Steroid Hormone Manipulation Reduces Brain Response to Reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26245498 DOI: 10.1038/npp.2015.236  0.065
2013 Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR. Serotonin 2A receptors contribute to the regulation of risk-averse decisions. Neuroimage. 83: 35-44. PMID 23810974 DOI: 10.1016/J.Neuroimage.2013.06.063  0.064
2015 Fisher PM, Grady CL, Madsen MK, Strother SC, Knudsen GM. 5-HTTLPR differentially predicts brain network responses to emotional faces. Human Brain Mapping. 36: 2842-51. PMID 25929825 DOI: 10.1002/hbm.22811  0.064
2014 Fisher PM, Madsen MK, Mc Mahon B, Holst KK, Andersen SB, Laursen HR, Hasholt LF, Siebner HR, Knudsen GM. Three-week bright-light intervention has dose-related effects on threat-related corticolimbic reactivity and functional coupling. Biological Psychiatry. 76: 332-9. PMID 24439303 DOI: 10.1016/j.biopsych.2013.11.031  0.063
2012 Ratner C, Ettrup A, Bueter M, Haahr ME, Compan V, le Roux CW, Levin B, Hansen HH, Knudsen GM. Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Y gastric bypass. Obesity (Silver Spring, Md.). 20: 2133-41. PMID 22450706 DOI: 10.1038/Oby.2012.75  0.063
2013 Thomsen G, Knudsen GM, Jensen PS, Ziebell M, Holst KK, Asenbaum S, Booij J, Darcourt J, Dickson JC, Kapucu OL, Nobili F, Sabri O, Sera T, Tatsch K, Tossici-Bolt L, et al. No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT. Ejnmmi Research. 3: 39. PMID 23688063 DOI: 10.1186/2191-219X-3-39  0.062
2013 van de Giessen E, Hesse S, Caan MW, Zientek F, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Guignard R, Akdemir UO, Knudsen GM, Nobili F, Pagani M, Vander Borght T, Van Laere K, et al. No association between striatal dopamine transporter binding and body mass index: a multi-center European study in healthy volunteers. Neuroimage. 64: 61-7. PMID 22982354 DOI: 10.1016/J.Neuroimage.2012.09.011  0.061
2012 Herth MM, Kramer V, Gillings N, Rösch F, Knudsen GM. Direct radiofluorination of [18F]MH.MZ for 5-HT2A receptor molecular imaging with PET Journal of Labelled Compounds and Radiopharmaceuticals. 55: 354-358. DOI: 10.1002/jlcr.2947  0.061
2009 Vinberg M, Trajkovska V, Bennike B, Knorr U, Knudsen GM, Kessing LV. The BDNF Val66Met polymorphism: Relation to familiar risk of affective disorder, BDNF levels and salivary cortisol Psychoneuroendocrinology. 34: 1380-1389. PMID 19473771 DOI: 10.1016/j.psyneuen.2009.04.014  0.061
2014 Macoveanu J, Knorr U, Skimminge A, Søndergaard MG, Jørgensen A, Fauerholdt-Jepsen M, Paulson OB, Knudsen GM, Siebner HR, Kessing LV. Altered reward processing in the orbitofrontal cortex and hippocampus in healthy first-degree relatives of patients with depression. Psychological Medicine. 44: 1183-95. PMID 23866315 DOI: 10.1017/S0033291713001815  0.06
2013 Herth MM, Andersen VL, Lehel S, Madsen J, Knudsen GM, Kristensen JL. Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation. Chemical Communications (Cambridge, England). 49: 3805-7. PMID 23535705 DOI: 10.1039/c3cc41027g  0.06
2013 Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR. Playing it safe but losing anyway--serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 919-30. PMID 23051938 DOI: 10.1016/J.Euroneuro.2012.09.006  0.059
2015 Jensen CG, Lansner J, Petersen A, Vangkilde SA, Ringkøbing SP, Frokjaer VG, Adamsen D, Knudsen GM, Denninger JW, Hasselbalch SG. Open and Calm--a randomized controlled trial evaluating a public stress reduction program in Denmark. Bmc Public Health. 15: 1245. PMID 26673225 DOI: 10.1186/S12889-015-2588-2  0.059
2010 Baaré WF, Vinberg M, Knudsen GM, Paulson OB, Langkilde AR, Jernigan TL, Kessing LV. Hippocampal volume changes in healthy subjects at risk of unipolar depression. Journal of Psychiatric Research. 44: 655-62. PMID 20096419 DOI: 10.1016/J.Jpsychires.2009.12.009  0.059
2013 Nielsen MB, Knudsen GM, Danino-Appleton V, Olsen JE, Thomsen LE. Comparison of heat stress responses of immobilized and planktonic Salmonella enterica serovar Typhimurium. Food Microbiology. 33: 221-7. PMID 23200655 DOI: 10.1016/j.fm.2012.09.020  0.058
2012 Koefoed P, Woldbye DPD, Hansen TVO, Eplov LF, Christiansen SH, Mors O, Kessing LV, Werge T, Kaipio K, Pesonen U, Fahmy T, Mellerup E, Jakobsen KD, Hansen ES, Knudsen GM, et al. Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression Acta Neuropsychiatrica. 24: 81-90. DOI: 10.1111/j.1601-5215.2011.00600.x  0.057
2010 Koefoed P, Woldbye DP, Hansen TO, Hansen ES, Knudsen GM, Bolwig TG, Rehfeld JF. Gene variations in the cholecystokinin system in patients with panic disorder Psychiatric Genetics. 20: 59-64. PMID 20023595 DOI: 10.1097/YPG.0b013e32833511a8  0.057
2012 Herth MM, Volk B, Pallagi K, Kofoed Bech L, Antoni FA, Knudsen GM, Kristensen JL. Synthesis and in vitro evaluation of oxindole derivatives as potential radioligands for 5-HT(7) receptor imaging with PET. Acs Chemical Neuroscience. 3: 1002-7. PMID 23259035 DOI: 10.1021/cn3001137  0.057
2008 Thomsen G, De Nijs R, Hogh-Rasmussen E, Frokjaer V, Svarer C, Knudsen GM. Required time delay from 99mTc-HMPAO injection to SPECT data acquisition: Healthy subjects and patients with rCBF pattern European Journal of Nuclear Medicine and Molecular Imaging. 35: 2212-2219. PMID 18542960 DOI: 10.1007/s00259-008-0836-8  0.056
2011 Rasmussen H, Ebdrup BH, Erritzoe D, Aggernaes B, Oranje B, Kalbitzer J, Pinborg LH, Baaré WFC, Svarer C, Lublin H, Knudsen GM, Glenthoj B. Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine Psychopharmacology. 213: 583-592. PMID 20614105 DOI: 10.1007/s00213-010-1941-5  0.056
2014 Rasmussen H, Ebdrup BH, Oranje B, Pinborg LH, Knudsen GM, Glenthøj B. Neocortical serotonin2A receptor binding predicts quetiapine associated weight gain in antipsychotic-naive first-episode schizophrenia patients. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1729-36. PMID 24830305 DOI: 10.1017/S1461145714000777  0.056
2014 Herth MM, Leth-Petersen S, Lehel S, Hansen M, Knudsen GM, Gillings N, Madsen J, Kristensen JL. Accelerating preclinical PET-screening: Reductive amination with [ 11C]methoxybenzaldehydes Rsc Advances. 4: 21347-21350. DOI: 10.1039/c4ra02506g  0.055
2010 Holm P, Ettrup A, Klein AB, Santini MA, El-Sayed M, Elvang AB, Stensbøl TB, Mikkelsen JD, Knudsen GM, Aznar S. Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice. Journal of Alzheimer's Disease : Jad. 20: 1201-13. PMID 20413853 DOI: 10.3233/JAD-2010-100117  0.055
2013 Jørgensen CV, Klein AB, El-Sayed M, Knudsen GM, Mikkelsen JD. Metabotropic glutamate receptor 2 and corticotrophin-releasing factor receptor-1 gene expression is differently regulated by BDNF in rat primary cortical neurons. Synapse (New York, N.Y.). 67: 794-800. PMID 23766023 DOI: 10.1002/syn.21689  0.054
2009 Erritzoe D, Frokjaer VG, Haugbol S, Marner L, Svarer C, Holst K, Baaré WFC, Rasmussen PM, Madsen J, Paulson OB, Knudsen GM. Corrigendum to "Brain serotonin 2A receptor binding: Relations to body mass index, tobacco and alcohol use" [NeuroImage 46 (2009) 23-30] (DOI:10.1016/j.neuroimage.2009.01.050) Neuroimage. 47: 780. DOI: 10.1016/J.Neuroimage.2009.05.001  0.054
2015 Hansen HD, Andersen VL, Lehel S, Magnussen JH, Dyssegaard A, Stroth N, Kristensen JL, Knudsen GM, Herth MM. Labeling and preliminary in vivo evaluation of the 5-HT(7) receptor selective agonist [(11)C]E-55888. Bioorganic & Medicinal Chemistry Letters. 25: 1901-4. PMID 25857944 DOI: 10.1016/j.bmcl.2015.03.039  0.054
2010 Miskowiak KW, Vinberg M, Harmer CJ, Ehrenreich H, Knudsen GM, Macoveanu J, Hansen AR, Paulson OB, Siebner HR, Kessing LV. Effects of erythropoietin on depressive symptoms and neurocognitive deficits in depression and bipolar disorder. Trials. 11: 97. PMID 20942940 DOI: 10.1186/1745-6215-11-97  0.053
2007 Knudsen GM. Proteomics for Biological Discovery. * Edited by Timothy D. Veenstra and John R. Yates III Briefings in Bioinformatics. 8: 467-468. DOI: 10.1093/bib/bbm021  0.051
2016 Miskowiak KW, Vinberg M, Glerup L, Paulson OB, Knudsen GM, Ehrenreich H, Harmer CJ, Kessing LV, Siebner HR, Macoveanu J. Neural correlates of improved executive function following erythropoietin treatment in mood disorders. Psychological Medicine. 1-13. PMID 26996196 DOI: 10.1017/S0033291716000209  0.051
2011 Klein AB, Williamson R, Santini MA, Clemmensen C, Ettrup A, Rios M, Knudsen GM, Aznar S. Blood BDNF concentrations reflect brain-tissue BDNF levels across species. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 347-53. PMID 20604989 DOI: 10.1017/S1461145710000738  0.051
2015 Jensen P, Feng L, Law I, Svarer C, Knudsen GM, Mikkelsen JD, de Nijs R, Larsen VA, Dyssegaard A, Thomsen G, Fischer W, Guilloteau D, Pinborg LH. TSPO Imaging in Glioblastoma Multiforme: A Direct Comparison Between 123I-CLINDE SPECT, 18F-FET PET, and Gadolinium-Enhanced MR Imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 1386-90. PMID 26182972 DOI: 10.2967/jnumed.115.158998  0.05
2009 Nielsen TR, Kornum BR, Moustgaard A, Gade A, Lind NM, Knudsen GM. A novel spatial Delayed Non-Match to Sample (DNMS) task in the Göttingen minipig Behavioural Brain Research. 196: 93-98. PMID 18706937 DOI: 10.1016/j.bbr.2008.07.019  0.049
2014 Visser AK, Meerlo P, Ettrup A, Knudsen GM, Bosker FJ, den Boer JA, Dierckx RA, van Waarde A. Acute social defeat does not alter cerebral 5-HT2A receptor binding in male Wistar rats. Synapse (New York, N.Y.). 68: 379-86. PMID 24823545 DOI: 10.1002/syn.21750  0.049
2014 Frokjaer VG, Erritzoe D, Holst KK, Madsen KS, Fisher PM, Madsen J, Svarer C, Knudsen GM. In abstinent MDMA users the cortisol awakening response is off-set but associated with prefrontal serotonin transporter binding as in non-users. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1119-28. PMID 24524290 DOI: 10.1017/S1461145714000066  0.048
2015 Aznar S, Knudsen GM. Depression and Alzheimer's disease: Is stress the initiating factor in a common neuropathological cascade? Advances in Alzheimer's Disease. 4: 145-161. DOI: 10.3233/978-1-61499-542-5-145  0.048
2015 Andersen VL, Hansen HD, Herth MM, Dyssegaard A, Knudsen GM, Kristensen JL. (11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand. Bioorganic & Medicinal Chemistry Letters. 25: 1053-6. PMID 25655720 DOI: 10.1016/j.bmcl.2015.01.017  0.048
2010 Licht CL, Knudsen GM, Sharp T. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience Letters. 476: 58-61. PMID 20381585 DOI: 10.1016/j.neulet.2010.04.002  0.047
2014 Hansen HD, Herth MM, Ettrup A, Andersen VL, Lehel S, Dyssegaard A, Kristensen JL, Knudsen GM. Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 640-6. PMID 24566002 DOI: 10.2967/jnumed.113.128983  0.047
2015 Jensen CG, Hjordt LV, Stenbæk DS, Andersen E, Back SK, Lansner J, Hageman I, Dam H, Nielsen AP, Knudsen GM, Frokjaer VG, Hasselbalch SG. Development and psychometric validation of the verbal affective memory test. Memory (Hove, England). 1-16. PMID 26401886 DOI: 10.1080/09658211.2015.1087573  0.047
2015 Henningsson S, Madsen KH, Pinborg A, Heede M, Knudsen GM, Siebner HR, Frokjaer VG. Role of emotional processing in depressive responses to sex-hormone manipulation: a pharmacological fMRI study. Translational Psychiatry. 5: e688. PMID 26624927 DOI: 10.1038/tp.2015.184  0.046
2012 Herth MM, Hansen HD, Ettrup A, Dyssegaard A, Lehel S, Kristensen J, Knudsen GM. Synthesis and evaluation of [¹¹C]Cimbi-806 as a potential PET ligand for 5-HT₇ receptor imaging. Bioorganic & Medicinal Chemistry. 20: 4574-81. PMID 22682922 DOI: 10.1016/j.bmc.2012.05.005  0.045
2013 Santini MA, Ratner C, Aznar S, Klein AB, Knudsen GM, Mikkelsen JD. Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia. Journal of Neuroscience Research. 91: 634-41. PMID 23404493 DOI: 10.1002/jnr.23198  0.044
2015 Magnussen JH, Ettrup A, Donat CK, Peters D, Pedersen MH, Knudsen GM, Mikkelsen JD. Radiosynthesis and in vitro validation of (3)H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand. European Journal of Pharmacology. 762: 35-41. PMID 25941084 DOI: 10.1016/j.ejphar.2015.04.036  0.044
2015 Magnussen JH, Ettrup A, Donat CK, Peters D, Pedersen MHF, Knudsen GM, Mikkelsen JD. Radiosynthesis and in vitro validation of 3H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand European Journal of Pharmacology. 762: 35-41. DOI: 10.1016/j.ejphar.2015.04.036  0.044
2015 O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik CS, Bennett RJ. Correction: Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome (Proceedings of the National Academy of Sciences United State of America (2015) 112, (7478-7483) DOI: 10.1073/pnas.1507082112) Proceedings of the National Academy of Sciences of the United States of America. 112: E3152. DOI: 10.1073/pnas.1509071112  0.044
2013 Ziebell M, Andersen BB, Pinborg LH, Knudsen GM, Stokholm J, Thomsen G, Karlsborg M, Høgh P, Mørk ML, Hasselbalch SG. Striatal dopamine transporter binding does not correlate with clinical severity in dementia with Lewy bodies. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1072-6. PMID 23637201 DOI: 10.2967/jnumed.112.114025  0.042
2012 Haahr ME, Rasmussen PM, Madsen K, Marner L, Ratner C, Gillings N, Baaré WF, Knudsen GM. Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry. Neuroimage. 61: 884-8. PMID 22709820 DOI: 10.1016/j.neuroimage.2012.03.050  0.042
2015 Ratner C, Madsen AN, Kristensen LV, Skov LJ, Pedersen KS, Mortensen OH, Knudsen GM, Raun K, Holst B. Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308: R973-82. PMID 25855307 DOI: 10.1152/Ajpregu.00219.2014  0.042
2011 Kornum BR, Knudsen GM. Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research Neuroscience and Biobehavioral Reviews. 35: 437-451. PMID 20553757 DOI: 10.1016/j.neubiorev.2010.05.004  0.041
2014 Andersen VL, Hansen HD, Herth MM, Knudsen GM, Kristensen JL. (11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand. Bioorganic & Medicinal Chemistry Letters. 24: 2408-11. PMID 24786133 DOI: 10.1016/j.bmcl.2014.04.044  0.041
2014 Lacivita E, Niso M, Hansen HD, Di Pilato P, Herth MM, Lehel S, Ettrup A, Montenegro L, Perrone R, Berardi F, Colabufo NA, Leopoldo M, Knudsen GM. Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT₇ receptor. Bioorganic & Medicinal Chemistry. 22: 1736-50. PMID 24508140 DOI: 10.1016/j.bmc.2014.01.016  0.04
2013 Thomsen G, Ziebell M, Jensen PS, da Cuhna-Bang S, Knudsen GM, Pinborg LH. No correlation between body mass index and striatal dopamine transporter availability in healthy volunteers using SPECT and [123I]PE2I. Obesity (Silver Spring, Md.). 21: 1803-6. PMID 23696269 DOI: 10.1002/oby.20225  0.04
2015 Jorgensen A, Magnusson P, Hanson LG, Kirkegaard T, Benveniste H, Lee H, Svarer C, Mikkelsen JD, Fink-Jensen A, Knudsen GM, Paulson OB, Bolwig TG, Jorgensen MB. Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression. Acta Psychiatrica Scandinavica. PMID 26138003 DOI: 10.1016/S0924-977X(16)31208-1  0.034
2011 Knudsen GM, Sommer HM, Sørensen ND, Olsen JE, Aabo S. Survival of Salmonella on cuts of beef carcasses subjected to dry aging Journal of Applied Microbiology. 111: 848-854. PMID 21714838 DOI: 10.1111/j.1365-2672.2011.05094.x  0.034
2014 Stenbæk DS, Hjordt LV, Haahr ME, Worm D, Hansen DL, Mortensen EL, Knudsen GM. Personality characteristics in surgery seeking and non-surgery seeking obese individuals compared to non-obese controls. Eating Behaviors. 15: 595-8. PMID 25218357 DOI: 10.1016/j.eatbeh.2014.08.008  0.034
2016 Stenbæk DS, Fisher PM, Budtz-Jørgensen E, Pinborg A, Hjordt LV, Jensen PS, Knudsen GM, Frokjaer VG. Sex hormone manipulation slows reaction time and increases labile mood in healthy women. Psychoneuroendocrinology. 68: 39-46. PMID 26943343 DOI: 10.1016/j.psyneuen.2016.02.023  0.033
2015 Beliveau V, Svarer C, Frokjaer VG, Knudsen GM, Greve DN, Fisher PM. Functional connectivity of the dorsal and median raphe nuclei at rest. Neuroimage. 116: 187-95. PMID 25963733 DOI: 10.1016/j.neuroimage.2015.04.065  0.031
2015 Herth MM, Knudsen GM. Current radiosynthesis strategies for 5-HT2A receptor PET tracers. Journal of Labelled Compounds & Radiopharmaceuticals. 58: 265-73. PMID 25997728 DOI: 10.1002/jlcr.3288  0.03
2010 Benveniste H, Fowler JS, Rooney WD, Scharf BA, Backus WW, Izrailtyan I, Knudsen GM, Hasselbalch SG, Volkow ND. Cocaine is pharmacologically active in the nonhuman primate fetal brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 1582-7. PMID 20080687 DOI: 10.1073/Pnas.0909585107  0.03
2015 Leth-Petersen S, Gabel-Jensen C, Gillings N, Lehel S, Hansen HD, Knudsen GM, Kristensen JL. Metabolic fate of hallucinogenic NBOMes. Chemical Research in Toxicology. PMID 26669514 DOI: 10.1021/acs.chemrestox.5b00450  0.027
2009 Knudsen GM. Testing for radioligand sensitivity to endogenous neurotransmitter release European Journal of Nuclear Medicine and Molecular Imaging. 36: 474. DOI: 10.1007/s00259-009-1067-3  0.027
2014 Andersen SB, McMahon B, Madsen MK, Knudsen GM, Holst KK, Møller P, Hageman I. Sweet taste sensitivity is influenced by 5-HTTLPR genotype and affected in seasonal affective disorder. Psychiatry Research. 220: 727-9. PMID 25113925 DOI: 10.1016/j.psychres.2014.07.045  0.026
2013 Hansen HD, Ettrup A, Herth MM, Dyssegaard A, Ratner C, Gillings N, Knudsen GM. Direct comparison of [(18) F]MH.MZ and [(18) F] altanserin for 5-HT2A receptor imaging with PET. Synapse (New York, N.Y.). 67: 328-37. PMID 23390031 DOI: 10.1002/syn.21643  0.025
2013 Rasmussen H, Ebdrup BH, Aggernaes B, Lublin H, Oranje B, Pinborg LH, Knudsen GM, Glenthøj B. Norquetiapine and depressive symptoms in initially antipsychotic-naive first-episode schizophrenia. Journal of Clinical Psychopharmacology. 33: 266-9. PMID 23422401 DOI: 10.1097/JCP.0b013e318287acc9  0.024
2014 Agn M, Svarer C, Frokjaer VG, Greve DN, Knudsen GM, Van Leemput K. Improved resolution and reliability in dynamic PET using Bayesian regularization of MRTM2 2014 Ieee 11th International Symposium On Biomedical Imaging, Isbi 2014. 955-958.  0.021
2012 Mikkelsen JD, Rasmussen MA, Meyer M, Knudsen GM. [Reprogramming of adult cells to neurons]. Ugeskrift For Laeger. 174: 786. PMID 22433543  0.018
2012 Ziebell M, Andersen BB, Thomsen G, Pinborg LH, Karlsborg M, Hasselbalch SG, Knudsen GM. Predictive value of dopamine transporter SPECT imaging with [¹²³I]PE2I in patients with subtle parkinsonian symptoms. European Journal of Nuclear Medicine and Molecular Imaging. 39: 242-50. PMID 22095050 DOI: 10.1007/s00259-011-1976-9  0.018
2012 Licht CL, Christoffersen M, Okholm M, Damgaard L, Fink-Jensen A, Knudsen GM, Erritzoe D. Simultaneous polysubstance use among Danish 3,4-methylenedioxymethamphetamine and hallucinogen users: combination patterns and proposed biological bases. Human Psychopharmacology. 27: 352-63. PMID 22696164 DOI: 10.1002/Hup.2234  0.016
2014 Stenbæk DS, Jensen CG, Holst KK, Mortensen EL, Knudsen GM, Frokjaer VG. Does Harm Avoidance mediate effects of recollected parental bonding on mental distress in adulthood? Comprehensive Psychiatry. 55: 1007-14. PMID 24439633 DOI: 10.1016/j.comppsych.2013.12.005  0.016
2010 Thomsen G, Knudsen GM. Procedure guideline for brain perfusion SPECT using 99mTc radiopharmaceuticals 3.0 Journal of Nuclear Medicine Technology. 38: 209. PMID 21078776 DOI: 10.2967/jnmt.109.071795  0.016
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