Year |
Citation |
Score |
2024 |
Zhu X, Fu Z, Dutchak K, Arabzadeh A, Milette S, Steinberger J, Morin G, Monast A, Pilon V, Kong T, Adams BN, Prando Munhoz E, Hosein HJ, Fang T, Su J, ... ... Huang S, et al. Co-targeting CDK4/6 and BRD4 promotes senescence and ferroptosis sensitivity in cancer. Cancer Research. PMID 38277141 DOI: 10.1158/0008-5472.CAN-23-1749 |
0.321 |
|
2020 |
Xue Y, Zhu X, Meehan B, Venneti S, Martinez D, Morin G, Itoua Maïga R, Chen H, Papadakis AI, Johnson RM, O'Sullivan MJ, Erdreich-Epstein A, Gotlieb WH, Park M, Judkins AR, ... ... Huang S, et al. SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors. The Journal of Pathology. PMID 32558936 DOI: 10.1002/Path.5493 |
0.332 |
|
2020 |
Tischkowitz M, Huang S, Banerjee S, Hague J, Hendricks WPD, Huntsman DG, Lang JD, Orlando KA, Oza AM, Pautier P, Ray-Coquard I, Trent JM, Wichter M, Witkowski L, McCluggage WG, et al. Small Cell Carcinoma of the Ovary, Hypercalcaemic Type - genetics, new treatment targets and current management guidelines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32156746 DOI: 10.1158/1078-0432.Ccr-19-3797 |
0.331 |
|
2019 |
Kong T, Xue Y, Cencic R, Zhu X, Monast A, Fu Z, Pilon V, Sangwan V, Guiot MC, Foulkes WD, Porco JA, Park M, Pelletier J, Huang S. eIF4A inhibitors suppress cell cycle feedback response and acquired resistance to CDK4/6 inhibition in cancer. Molecular Cancer Therapeutics. PMID 31395685 DOI: 10.1158/1535-7163.Mct-19-0162 |
0.395 |
|
2019 |
Shorstova T, Marques M, Su J, Johnston J, Kleinman CL, Hamel N, Huang S, Alaoui-Jamali MA, Foulkes WD, Witcher M. SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors. Cancer Research. PMID 30877105 DOI: 10.1158/0008-5472.Can-18-1545 |
0.418 |
|
2019 |
Xue Y, Meehan B, Macdonald E, Venneti S, Wang XQD, Witkowski L, Jelinic P, Kong T, Martinez D, Morin G, Firlit M, Abedini A, Johnson RM, Cencic R, Patibandla J, ... ... Huang S, et al. CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary. Nature Communications. 10: 558. PMID 30718512 DOI: 10.1038/S41467-018-06958-9 |
0.423 |
|
2019 |
Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, ... ... Huang S, et al. SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer. Nature Communications. 10: 557. PMID 30718506 DOI: 10.1038/S41467-019-08380-1 |
0.407 |
|
2019 |
Rayes RF, Mouhanna JG, Wang C, Milette S, Wong C, Usatii M, Giannias B, Mot R, Chandrasekaran A, Moraes C, Huang S, Quail D, Walsh L, Sangwan V, Bertos N, et al. Abstract 2799: Targeting CXCR2-mediated neutrophil recruitment to lung cancer Cancer Research. 79: 2799-2799. DOI: 10.1158/1538-7445.Am2019-2799 |
0.314 |
|
2018 |
Karimzadeh M, Jandaghi P, Papadakis AI, Trainor S, Rung J, Gonzàlez-Porta M, Scelo G, Vasudev NS, Brazma A, Huang S, Banks RE, Lathrop M, Najafabadi HS, Riazalhosseini Y. Aberration hubs in protein interaction networks highlight actionable targets in cancer. Oncotarget. 9: 25166-25180. PMID 29861861 DOI: 10.18632/Oncotarget.25382 |
0.378 |
|
2018 |
Perron G, Jandaghi P, Solanki S, Safisamghabadi M, Storoz C, Karimzadeh M, Papadakis AI, Arseneault M, Scelo G, Banks RE, Tost J, Lathrop M, Tanguay S, Brazma A, Huang S, et al. A General Framework for Interrogation of mRNA Stability Programs Identifies RNA-Binding Proteins that Govern Cancer Transcriptomes. Cell Reports. 23: 1639-1650. PMID 29742422 DOI: 10.1016/J.Celrep.2018.04.031 |
0.341 |
|
2018 |
Wang C, Rayes R, Mouhanna J, Giannias B, Chandrasekaran A, Mot R, Moraes C, Huang S, Cools-Lartigue J, Bertos N, Ferri L, Spicer J. Abstract 1099: Molecular drivers of neutrophil recruitment to primary non-small cell lung cancer Cancer Research. 78: 1099-1099. DOI: 10.1158/1538-7445.Am2018-1099 |
0.359 |
|
2017 |
Zhan Y, Guo J, Yang W, Goncalves C, Rzymski T, Dreas A, Żyłkiewicz E, Mikulski M, Brzózka K, Golas A, Kong Y, Ma M, Huang F, Huor B, Guo Q, ... ... Huang S, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma. The Journal of Clinical Investigation. PMID 29035277 DOI: 10.1172/Jci91258 |
0.401 |
|
2017 |
Jandaghi P, Najafabadi HS, Bauer A, Papadakis AI, Fassan M, Hall A, Monast A, Safisamghabadi M, Doeberitz MvK, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Sipos B, Auld D, ... ... Huang S, et al. Abstract 1135: DRD2 is critical for pancreatic cancer and promises pharmacological therapy by already established antagonists Cancer Research. 77: 1135-1135. DOI: 10.1158/1538-7445.Am2017-1135 |
0.356 |
|
2016 |
Jandaghi P, Najafabadi HS, Bauer AS, Papadakis AI, Fassan M, Hall A, Monast A, von Knebel Doeberitz M, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Sipos B, Auld D, Lathrop M, ... ... Huang S, et al. Expression of DRD2 is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice. Gastroenterology. PMID 27578530 DOI: 10.1053/J.Gastro.2016.08.040 |
0.319 |
|
2015 |
Adare A, Afanasiev S, Aidala C, Ajitanand NN, Akiba Y, Akimoto R, Al-Bataineh H, Alexander J, Alfred M, Al-Ta'ani H, Andrews KR, Angerami A, Aoki K, Apadula N, Aphecetche L, ... ... Huang S, et al. Measurements of Elliptic and Triangular Flow in High-Multiplicity 3He+Au Collisions at √(s(NN))=200 GeV. Physical Review Letters. 115: 142301. PMID 26551807 DOI: 10.1103/Physrevlett.115.142301 |
0.359 |
|
2015 |
Mui MZ, Zhou Y, Blanchette P, Chughtai N, Knight JF, Gruosso T, Papadakis AI, Huang S, Park M, Gingras AC, Branton PE. The human adenovirus type 5 E4orf4 protein targets two phosphatase regulators of the Hippo signaling pathway. Journal of Virology. PMID 26085163 DOI: 10.1128/Jvi.03710-14 |
0.397 |
|
2015 |
Andrei AZ, Hall A, Smith AL, Bascuñana C, Malina A, Connor A, Altinel-Omeroglu G, Huang S, Pelletier J, Huntsman D, Gallinger S, Omeroglu A, Metrakos P, Zogopoulos G. Increased in vitro and in vivo sensitivity of BRCA2-associated pancreatic cancer to the poly(ADP-ribose) polymerase-1/2 inhibitor BMN 673. Cancer Letters. 364: 8-16. PMID 25864590 DOI: 10.1016/J.Canlet.2015.04.003 |
0.327 |
|
2015 |
Papadakis AI, Sun C, Knijnenburg TA, Xue Y, Grernrum W, Hölzel M, Nijkamp W, Wessels LF, Beijersbergen RL, Bernards R, Huang S. SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer. Cell Research. 25: 445-58. PMID 25656847 DOI: 10.1038/Cr.2015.16 |
0.406 |
|
2015 |
Papadakis A, Sun C, Knijnenburg T, Xue Y, Grernrum W, Hölzel M, Nijkamp W, Wessels L, Beijersbergen R, Bernards R, Huang S. Abstract LB-240: SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-240 |
0.388 |
|
2014 |
Drosten M, Sum EY, Lechuga CG, Simón-Carrasco L, Jacob HK, GarcÃa-Medina R, Huang S, Beijersbergen RL, Bernards R, Barbacid M. Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 111: 15155-60. PMID 25288756 DOI: 10.1073/Pnas.1417549111 |
0.317 |
|
2014 |
Lai AZ, Cory S, Zhao H, Gigoux M, Monast A, Guiot MC, Huang S, Tofigh A, Thompson C, Naujokas M, Marcus VA, Bertos N, Sehat B, Perera RM, Bell ES, et al. Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer. Science Signaling. 7: ra38. PMID 24757178 DOI: 10.1126/Scisignal.2004839 |
0.435 |
|
2014 |
Sun C, Hobor S, Bertotti A, Zecchin D, Huang S, Galimi F, Cottino F, Prahallad A, Grernrum W, Tzani A, Schlicker A, Wessels LF, Smit EF, Thunnissen E, Halonen P, et al. Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3. Cell Reports. 7: 86-93. PMID 24685132 DOI: 10.1016/J.Celrep.2014.02.045 |
0.428 |
|
2014 |
Sun C, Wang L, Huang S, Heynen GJ, Prahallad A, Robert C, Haanen J, Blank C, Wesseling J, Willems SM, Zecchin D, Hobor S, Bajpe PK, Lieftink C, Mateus C, et al. Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma. Nature. 508: 118-22. PMID 24670642 DOI: 10.1038/Nature13121 |
0.347 |
|
2013 |
Walker JA, Gouzi JY, Long JB, Huang S, Maher RC, Xia H, Khalil K, Ray A, Van Vactor D, Bernards R, Bernards A. Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. Plos Genetics. 9: e1003958. PMID 24278035 DOI: 10.1371/Journal.Pgen.1003958 |
0.395 |
|
2013 |
Bajpe PK, Heynen GJ, Mittempergher L, Grernrum W, de Rink IA, Nijkamp W, Beijersbergen RL, Bernards R, Huang S. The corepressor CTBP2 is a coactivator of retinoic acid receptor/retinoid X receptor in retinoic acid signaling. Molecular and Cellular Biology. 33: 3343-53. PMID 23775127 DOI: 10.1128/Mcb.01213-12 |
0.326 |
|
2012 |
Huang S, Hölzel M, Knijnenburg T, Schlicker A, Roepman P, McDermott U, Garnett M, Grernrum W, Sun C, Prahallad A, Groenendijk FH, Mittempergher L, Nijkamp W, Neefjes J, Salazar R, et al. MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling Cell. 151: 937-950. PMID 23178117 DOI: 10.1016/J.Cell.2012.10.035 |
0.401 |
|
2012 |
Prahallad A, Sun C, Huang S, Di Nicolantonio F, Salazar R, Zecchin D, Beijersbergen RL, Bardelli A, Bernards R. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature. 483: 100-3. PMID 22281684 DOI: 10.1038/Nature10868 |
0.391 |
|
2010 |
Hölzel M, Huang S, Koster J, Ora I, Lakeman A, Caron H, Nijkamp W, Xie J, Callens T, Asgharzadeh S, Seeger RC, Messiaen L, Versteeg R, Bernards R. NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome. Cell. 142: 218-29. PMID 20655465 DOI: 10.1016/J.Cell.2010.06.004 |
0.316 |
|
2010 |
Hölzel M, Huang S, Koster J, Ora I, Lakeman A, Caron HN, Callens T, Xie J, Nijkamp W, Asgharzadeh S, Seeger RC, Messiaen L, Versteeg R, Bernards R. Abstract A30: NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcme10-A30 |
0.315 |
|
2009 |
Huang S, Laoukili J, Epping MT, Koster J, Hölzel M, Westerman BA, Nijkamp W, Hata A, Asgharzadeh S, Seeger RC, Versteeg R, Beijersbergen RL, Bernards R. ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome. Cancer Cell. 15: 328-40. PMID 19345331 DOI: 10.1016/J.Ccr.2009.02.023 |
0.336 |
|
2005 |
Huang S, O'Shea EK. A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation. Genetics. 169: 1859-71. PMID 15695358 DOI: 10.1534/Genetics.104.038695 |
0.616 |
|
2001 |
Huang S, Jeffery DA, Anthony MD, O'Shea EK. Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain. Molecular and Cellular Biology. 21: 6695-705. PMID 11533256 DOI: 10.1128/Mcb.21.19.6695-6705.2001 |
0.659 |
|
2001 |
Piffat KA, Hrdlicková R, Nehyba J, Ikeda T, Liss A, Huang S, Sif S, Gilmore TD, Bose HR. The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB. Molecular Cell Biology Research Communications : McBrc. 4: 266-75. PMID 11529676 DOI: 10.1006/Mcbr.2001.0290 |
0.304 |
|
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