Athanassios Giannis - Publications

Affiliations: 
1992-1997 Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Nordrhein-Westfalen, Germany 
 1997-2002 Universität Karlsruhe 
 2002- Universität Leipzig, Leipzig, Sachsen, Germany 
Area:
Organic Chemistry, Biochemistry, Medicinal Chemistry
Website:
https://org.chemie.uni-leipzig.de/en/institute-of-organic-chemistry/giannis-group/prof-a-giannis/

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Meyer D, Smeilus T, Pliatsika D, Mousavizadeh F, Giannis A. Synthesis of novel C-9 carbon substituted derivatives of artemisinin. Bioorganic & Medicinal Chemistry. PMID 28341405 DOI: 10.1016/J.Bmc.2017.03.021  0.343
2016 Antoniou A, Chatzopoulou M, Bantzi M, Athanassopoulos CM, Giannis A, Pitsinos EN. Identification of Gli-mediated transcription inhibitors through synthesis and evaluation of taepeenin D analogues Medchemcomm. 7: 2328-2331. DOI: 10.1039/C6Md00354K  0.356
2016 Psarra V, Fousteris MA, Hennig L, Bantzi M, Giannis A, Nikolaropoulos SS. Identification of azepinone fused tetracyclic heterocycles as new chemotypes with protein kinase inhibitory activities Tetrahedron. 72: 2376-2385. DOI: 10.1016/J.Tet.2016.03.048  0.365
2015 Heretsch P, Giannis A. The Veratrum and Solanum alkaloids. The Alkaloids. Chemistry and Biology. 74: 201-32. PMID 25845062 DOI: 10.1016/Bs.Alkal.2014.11.002  0.627
2015 Smeilus T, Hennig L, Beyer L, Sieler J, Giannis A. The Mistake in Carl Bosch's PhD Thesis: A Contribution to "Retro-Chemistry" Synthesis (Germany). 47: 1887-1892. DOI: 10.1055/S-0034-1380495  0.301
2014 Wratil PR, Rigol S, Solecka B, Kohla G, Kannicht C, Reutter W, Giannis A, Nguyen LD. A novel approach to decrease sialic acid expression in cells by a C-3-modified N-acetylmannosamine. The Journal of Biological Chemistry. 289: 32056-63. PMID 25278018 DOI: 10.1074/Jbc.M114.608398  0.323
2014 Rabe S, Moschner J, Bantzi M, Heretsch P, Giannis A. C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog. Beilstein Journal of Organic Chemistry. 10: 1564-9. PMID 25161712 DOI: 10.3762/Bjoc.10.161  0.629
2014 Heretsch P, Giannis A. Cyclopamine and Congeners Natural Products in Medicinal Chemistry. 545-564. DOI: 10.1002/9783527676545.ch15  0.58
2013 Moschner J, Chentsova A, Eilert N, Rovardi I, Heretsch P, Giannis A. Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling. Beilstein Journal of Organic Chemistry. 9: 2328-35. PMID 24367396 DOI: 10.3762/Bjoc.9.267  0.665
2012 Aurich A, Specht R, Müller RA, Stottmeister U, Yovkova V, Otto C, Holz M, Barth G, Heretsch P, Thomas FA, Sicker D, Giannis A. Microbiologically produced carboxylic acids used as building blocks in organic synthesis. Sub-Cellular Biochemistry. 64: 391-423. PMID 23080261 DOI: 10.1007/978-94-007-5055-5_19  0.673
2012 Seifert K, Büttner A, Rigol S, Eilert N, Wandel E, Giannis A. Potent small molecule Hedgehog agonists induce VEGF expression in vitro. Bioorganic & Medicinal Chemistry. 20: 6465-81. PMID 22985958 DOI: 10.1016/J.Bmc.2012.08.026  0.3
2011 Heretsch P, Büttner A, Tzagkaroulaki L, Zahn S, Kirchner B, Giannis A. Exo-cyclopamine--a stable and potent inhibitor of hedgehog-signaling. Chemical Communications (Cambridge, England). 47: 7362-4. PMID 21589966 DOI: 10.1039/C1Cc11782C  0.662
2011 Vasconcelos RS, Silva LF, Giannis A. Synthesis of tetrahydrofurans by cyclization of homoallylic alcohols with iodine/iodine(III). The Journal of Organic Chemistry. 76: 1499-502. PMID 21244003 DOI: 10.1021/Jo102413U  0.305
2010 Heretsch P, Tzagkaroulaki L, Giannis A. Modulators of the hedgehog signaling pathway. Bioorganic & Medicinal Chemistry. 18: 6613-24. PMID 20708941 DOI: 10.1016/J.Bmc.2010.07.038  0.626
2010 Heretsch P, Rabe S, Giannis A. A biomimetic approach to C-nor-D-homo-steroids. Journal of the American Chemical Society. 132: 9968-9. PMID 20597501 DOI: 10.1021/Ja103152K  0.647
2010 Büttner A, Cottin T, Xu J, Tzagkaroulaki L, Giannis A. Serotonin derivatives as a new class of non-ATP-competitive receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry. 18: 3387-402. PMID 20456957 DOI: 10.1016/J.Bmc.2010.04.001  0.32
2010 Heretsch P, Tzagkaroulaki L, Giannis A. Cyclopamine and hedgehog signaling: chemistry, biology, medical perspectives. Angewandte Chemie (International Ed. in English). 49: 3418-27. PMID 20429080 DOI: 10.1002/Anie.200906967  0.61
2010 Wetzel S, Wilk W, Chammaa S, Sperl B, Roth AG, Yektaoglu A, Renner S, Berg T, Arenz C, Giannis A, Oprea TI, Rauh D, Kaiser M, Waldmann H. A scaffold-tree-merging strategy for prospective bioactivity annotation of gamma-pyrones. Angewandte Chemie (International Ed. in English). 49: 3666-70. PMID 20394088 DOI: 10.1002/Anie.200906555  0.677
2010 Churruca F, Fousteris M, Ishikawa Y, Rekowski Mv, Hounsou C, Surrey T, Giannis A. A novel approach to indoloditerpenes by Nazarov photocyclization: synthesis and biological investigations of terpendole E analogues. Organic Letters. 12: 2096-9. PMID 20387880 DOI: 10.1021/Ol100579W  0.36
2010 von Wantoch Rekowski M, Pyriochou A, Papapetropoulos N, Stössel A, Papapetropoulos A, Giannis A. Synthesis and biological evaluation of oxadiazole derivatives as inhibitors of soluble guanylyl cyclase. Bioorganic & Medicinal Chemistry. 18: 1288-96. PMID 20036129 DOI: 10.1016/J.Bmc.2009.12.027  0.384
2010 HENK T, GIANNIS A, SANDHOFF K. ChemInform Abstract: Wittig Olefination of Unprotected Carbohydrates with a Semistabilized Ylide. Cheminform. 23: no-no. DOI: 10.1002/chin.199220276  0.542
2010 Heretsch P, Tzagkaroulaki L, Giannis A. Cyclopamin und der Hedgehog-Signaltransduktionsweg: Chemie, Biologie, medizinische Perspektiven Angewandte Chemie. 122: 3492-3502. DOI: 10.1002/Ange.200906967  0.62
2009 Heretsch P, Rabe S, Giannis A. Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine. Organic Letters. 11: 5410-2. PMID 19883099 DOI: 10.1021/Ol902270F  0.692
2009 Giannis A, Heretsch P, Sarli V, Stössel A. Synthesis of cyclopamine using a biomimetic and diastereoselective approach. Angewandte Chemie (International Ed. in English). 48: 7911-4. PMID 19591183 DOI: 10.1002/Anie.200902520  0.652
2009 Büttner A, Seifert K, Cottin T, Sarli V, Tzagkaroulaki L, Scholz S, Giannis A. Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway. Bioorganic & Medicinal Chemistry. 17: 4943-54. PMID 19541490 DOI: 10.1016/J.Bmc.2009.06.008  0.318
2009 Sardon T, Cottin T, Xu J, Giannis A, Vernos I. Development and biological evaluation of a novel aurora A kinase inhibitor. Chembiochem : a European Journal of Chemical Biology. 10: 464-78. PMID 19199284 DOI: 10.1002/Cbic.200800600  0.325
2009 Giannis A, Heretsch P, Sarli V, Stößel A. Cover Picture: Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach (Angew. Chem. Int. Ed. 42/2009) Angewandte Chemie International Edition. 48: 7707-7707. DOI: 10.1002/Anie.200904019  0.652
2009 Giannis A, Heretsch P, Sarli V, Stößel A. Titelbild: Synthese von Cyclopamin unter Verwendung biomimetischer und diastereoselektiver Transformationen (Angew. Chem. 42/2009) Angewandte Chemie. 121: 7843-7843. DOI: 10.1002/Ange.200904019  0.671
2009 Giannis A, Heretsch P, Sarli V, Stößel A. Synthese von Cyclopamin unter Verwendung biomimetischer und diastereoselektiver Transformationen Angewandte Chemie. 121: 8052-8055. DOI: 10.1002/Ange.200902520  0.671
2008 Heretsch P, Thomas F, Aurich A, Krautscheid H, Sicker D, Giannis A. Syntheses with a chiral building block from the citric acid cycle: (2R,3S)-isocitric acid by fermentation of sunflower oil. Angewandte Chemie (International Ed. in English). 47: 1958-60. PMID 18236482 DOI: 10.1002/Anie.200705000  0.64
2008 Mann S, Sarli V, Giannis A. A convenient synthesis of functionalized furans Synthesis. 2617-2625. DOI: 10.1055/S-2008-1067183  0.347
2008 Heretsch P, Thomas F, Aurich A, Krautscheid H, Sicker D, Giannis A. Synthesen mit einem chiralen Baustein aus dem Citratzyklus: (2R,3S)-Isocitronensäure aus einer Fermentation mit Sonnenblumenöl Angewandte Chemie. 120: 1984-1986. DOI: 10.1002/Ange.200705000  0.607
2007 Batova A, Lam T, Wascholowski V, Yu AL, Giannis A, Theodorakis EA. Synthesis and evaluation of caged Garcinia xanthones. Organic & Biomolecular Chemistry. 5: 494-500. PMID 17252132 DOI: 10.1039/B612903J  0.35
2007 Müller C, Gross D, Sarli V, Gartner M, Giannis A, Bernhardt G, Buschauer A. Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology. 59: 157-64. PMID 16703323 DOI: 10.1007/S00280-006-0254-1  0.301
2007 Heretsch P, Giannis A. An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues Synthesis. 2614-2616. DOI: 10.1055/S-2007-983843  0.681
2005 Sarli V, Huemmer S, Sunder-Plassmann N, Mayer TU, Giannis A. Synthesis and biological evaluation of novel EG5 inhibitors. Chembiochem : a European Journal of Chemical Biology. 6: 2005-13. PMID 16216042 DOI: 10.1002/Cbic.200500168  0.389
2005 Sunder-Plassmann N, Sarli V, Gartner M, Utz M, Seiler J, Huemmer S, Mayer TU, Surrey T, Giannis A. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorganic & Medicinal Chemistry. 13: 6094-111. PMID 16084101 DOI: 10.1016/J.Bmc.2005.06.027  0.369
2005 Mazitschek R, Huwe A, Giannis A. Synthesis and biological evaluation of novel fumagillin and ovalicin analogues. Organic & Biomolecular Chemistry. 3: 2150-4. PMID 15917904 DOI: 10.1039/B503163J  0.336
2005 Gartner M, Sunder-Plassmann N, Seiler J, Utz M, Vernos I, Surrey T, Giannis A. Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5. Chembiochem : a European Journal of Chemical Biology. 6: 1173-7. PMID 15912555 DOI: 10.1002/Cbic.200500005  0.32
2005 Gartner M, Müller T, Simon JC, Giannis A, Sleeman JP. Aristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent. Chembiochem : a European Journal of Chemical Biology. 6: 171-7. PMID 15593112 DOI: 10.1002/Cbic.200400195  0.304
2004 Al-Rawi S, Hinderlich S, Reutter W, Giannis A. Synthesis and biochemical properties of reversible inhibitors of UDP-N-acetylglucosamine 2-epimerase. Angewandte Chemie (International Ed. in English). 43: 4366-70. PMID 15368395 DOI: 10.1002/Anie.200453863  0.345
2004 Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H. Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angewandte Chemie (International Ed. in English). 43: 224-8. PMID 14695616 DOI: 10.1002/Anie.200352582  0.34
2004 Schulze A, Giannis A. IBX-mediated conversion of primary alcohols and aldehydes to N-hydroxysuccinimide esters Advanced Synthesis and Catalysis. 346: 252-256. DOI: 10.1002/Adsc.200303195  0.328
2003 Pitsinos EN, Wascholowski V, Karaliota S, Rigou C, Couladouros EA, Giannis A. Synthesis and evaluation of three novel scyphostatin analogues as neutral sphingomyelinase inhibitors. Chembiochem : a European Journal of Chemical Biology. 4: 1223-5. PMID 14613115 DOI: 10.1002/Cbic.200300667  0.314
2003 Stieber F, Grether U, Mazitschek R, Soric N, Giannis A, Waldmann H. Multistep solid-phase synthesis of an antibiotic and receptor tyrosine kinase inhibitors using the traceless phenylhydrazide linker. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 3282-91. PMID 12866072 DOI: 10.1002/Chem.200304821  0.314
2002 Stahl P, Kissau L, Mazitschek R, Giannis A, Waldmann H. Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors. Angewandte Chemie (International Ed. in English). 41: 1174-8. PMID 12491250 DOI: 10.1002/1521-3773(20020402)41:7<1174::Aid-Anie1174>3.0.Co;2-V  0.304
2002 Arenz C, Thutewohl M, Block O, Waldmann H, Altenbach HJ, Giannis A. Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase. Chembiochem : a European Journal of Chemical Biology. 2: 141-3. PMID 11828438 DOI: 10.1002/1439-7633(20010202)2:2<141::Aid-Cbic141>3.0.Co;2-P  0.718
2001 Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H. Total synthesis and biological evaluation of the nakijiquinones. Journal of the American Chemical Society. 123: 11586-93. PMID 11716712 DOI: 10.1021/Ja011413I  0.367
2001 Arenz C, Gartner M, Wascholowski V, Giannis A. Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase Bioorganic and Medicinal Chemistry. 9: 2901-2904. PMID 11597471 DOI: 10.1016/S0968-0896(01)00165-1  0.727
2001 Ficht S, Mülbaier M, Giannis A. Development of new and efficient polymer-supported hypervalent iodine reagents Tetrahedron. 57: 4863-4866. DOI: 10.1016/S0040-4020(01)00424-0  0.304
2001 Mülbaier M, Giannis A. Festphasen-gebundenes IBX: Synthese und Oxidationseigenschaften Angewandte Chemie. 113: 4530-4532. DOI: 10.1002/1521-3757(20011203)113:23<4530::Aid-Ange4530>3.0.Co;2-1  0.354
2001 Arenz C, Giannis A. Synthesis of the first selective irreversible inhibitor of neutral sphingomyelinase European Journal of Organic Chemistry. 137-140. DOI: 10.1002/(Sici)1521-3773(20000417)39:8<1440::Aid-Anie1440>3.0.Co;2-R  0.732
2000 Rübsam F, Mazitschek R, Giannis A. Synthesis of chiral piperazinones as versatile scaffolds for peptidomimetics Tetrahedron. 56: 8481-8487. DOI: 10.1016/S0040-4020(00)00787-0  0.348
2000 Arenz C, Giannis A. Synthese des ersten selektiven irreversiblen Inhibitors der neutralen Sphingomyelinase Angewandte Chemie. 112: 1498-1500. DOI: 10.1002/(Sici)1521-3757(20000417)112:8<1498::Aid-Ange1498>3.0.Co;2-Y  0.725
1998 Van Echten-Deckert G, Giannis A, Schwarz A, Futerman AH, Sandhoff K. 1-Methylthiodihydroceramide, a novel analog of dihydroceramide, stimulates sphinganine degradation resulting in decreased de novo sphingolipid biosynthesis Journal of Biological Chemistry. 273: 1184-1191. PMID 9422785 DOI: 10.1074/Jbc.273.2.1184  0.562
1996 Schick A, Kolter T, Giannis A, Sandhoff K. Synthesis of phosphoramide analogues of sphinganine-1-phosphate Tetrahedron. 52: 2945-2956. DOI: 10.1016/0040-4020(95)01119-6  0.635
1995 Schick A, Kolter T, Giannis A, Sandhoff K. Synthesis of phosphonate analogues of sphinganine-1-phosphate and sphingosine-1-phosphate Tetrahedron. 51: 11207-11218. DOI: 10.1016/0040-4020(95)00688-5  0.632
1993 Liessem B, Giannis A, Sandhoff K, Nieger M. Synthese von 2-acetamido-1,4-imino-1,2,4-tridesoxy-d- galaktitol und kompetitive Inhibition der humanen lysosomalen β-hexosaminidase A Carbohydrate Research. 250: 19-30. PMID 8143290 DOI: 10.1016/0008-6215(93)84151-U  0.604
1992 Zeitler R, Giannis A, Danneschewski S, Henk E, Henk T, Bauer C, Reutter W, Sandhoff K. Inhibition of N-acetylglucosamine kinase and N-acetylmannosamine kinase by 3-O-methyl-N-acetyl-D-glucosamine in vitro European Journal of Biochemistry. 204: 1165-1168. PMID 1312935 DOI: 10.1111/J.1432-1033.1992.Tb16743.X  0.585
1992 Brenner-Weiß G, Giannis A, Sandhoff K. Synthesis of potential inhibitors of the glycosphingolipid biosynthesis Tetrahedron. 48: 5855-5860. DOI: 10.1016/S0040-4020(01)90177-2  0.646
1992 Henk T, Giannis A, Sandhoff K. Wittig Olefination of Unprotected Carbohydrates with a Semistabilized Ylide Liebigs Annalen Der Chemie. 1992: 167-168. DOI: 10.1002/Jlac.199219920130  0.593
1991 Giannis A, Henk T. Synthese chiraler Bausteine ausD-glucosamin-hydrochlorid Liebigs Annalen Der Chemie. 1991: 789-793. DOI: 10.1002/Jlac.1991199101135  0.37
1990 Singh NP, Schmidt RR, Giannis A, Henk E, Kolter T, Sandhoff K. Synthesis of 2-Carboxy-Substituted Sphingosine Derivatives Journal of Carbohydrate Chemistry. 9: 543-559. DOI: 10.1080/07328309008543852  0.633
1990 Giannis A, Henk T. Chirospecific synthesis of amino acids, amino aldehydes and amino alcohols from D-glucosamine hydrochloride. A multigram synthesis of N-boc-L-serinal Tetrahedron Letters. 31: 1253-1256. DOI: 10.1016/S0040-4039(00)88778-X  0.332
1989 Giannis A, Sandhoff K. LiBH4(NaBH4)/Me3SiCl, an Unusually Strong and Versatile Reducing Agent Angewandte Chemie International Edition in English. 28: 218-220. DOI: 10.1002/Anie.198902181  0.551
1989 Giannis A, Sandhoff K. LiBH4(NaBH4)/Me3SiCl, ein ungewöhnlich starkes und vielseitig einsetzbares Reduktionsmittel Angewandte Chemie. 101: 220-222. DOI: 10.1002/Ange.19891010231  0.565
1988 Giannis A, Münster P, Sandhoff K, Steglich W. Fragmentation and wittig olefination of glucosamine derivatives-a simple route to open chain amino sugars and chiral glycerols Tetrahedron. 44: 7177-7180. DOI: 10.1016/S0040-4020(01)86086-5  0.605
1987 Giannis A, Sandhoff K. Diastereoselektive synthese von funktionalisierten C-α- und -β-glykosylderivaten der 2-acetamido-2-desoxy-d-glucose Carbohydrate Research. 171: 201-210. DOI: 10.1016/S0008-6215(00)90887-5  0.586
1985 Giannis A, Sandhoff K. Stereoselective synthesis of α- C-allyl-glycopyranosides Tetrahedron Letters. 26: 1479-1482. DOI: 10.1016/S0040-4039(00)98529-0  0.628
1981 Reetz MT, Giannis A. Lewis Acid Mediated A-Thioalkylation of Ketones Synthetic Communications. 11: 315-322. DOI: 10.1080/00397918108063611  0.379
1981 Reetz MT, Giannis A. LEWIS ACID MEDIATED α‐THIOALKYLATION OF KETONES Cheminform. 12: 315-322. DOI: 10.1002/Chin.198143125  0.365
1981 REETZ MT, MAIER WF, CHATZIIOSIFIDIS I, GIANNIS A, HEIMBACH H, LOEWE U. ChemInform Abstract: LEWIS ACID MEDIATED α-ALKYLATION OF CARBONYL COMPOUNDS. VII. REGIO AND POSITION SPECIFIC α-TERT-ALKYLATION OF KETONES Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198109166  0.65
1981 REETZ MT, MAIER WF, HEIMBACH H, GIANNIS A, ANASTASSIOUS G. ChemInform Abstract: LEWIS ACID MEDIATED α-ALKYLATION OF CARBONYL COMPOUNDS. VI. OPTIMIZATION OF THE PROCEDURE FOR THE α-TERT-ALKYLATION OF KETONES AND ALDEHYDES Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198109165  0.648
1980 Reetz MT, Maier WF, Chatziiosifidis I, Giannis A, Heimbach H, Löwe U. Lewis-Säure-bedingte α-Alkylierung von Carbonylverbindungen, VII. Regio- und positionsspezifische α-tert-Alkylierung von Ketonen Chemische Berichte. 113: 3741-3757. DOI: 10.1002/Cber.19801131208  0.476
1980 Reetz MT, Maier WF, Heimbach H, Giannis A, Anastassious G. Lewis-Säure-bedingte α-Alkylierung von Carbonylverbindungen, VI. Optimierung des Verfahrens zur α-tert-Alkylierung von Ketonen und Aldehyden Chemische Berichte. 113: 3734-3740. DOI: 10.1002/Cber.19801131207  0.486
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