Year |
Citation |
Score |
2022 |
Sexton M, Malachowski WP, Yap GPA, Rachii D, Feldman G, Krasley AT, Chen Z, Tran MA, Wiley K, Matei A, Petersen S, Tien ST. Catalytic Enantioselective Birch-Heck Sequence for the Synthesis of Phenanthridinone Derivatives with an All-Carbon Quaternary Stereocenter. The Journal of Organic Chemistry. PMID 34985891 DOI: 10.1021/acs.joc.1c02523 |
0.319 |
|
2019 |
Sexton ME, Okazaki A, Yu Z, van Venrooy A, Schmink JR, Malachowski WP. Palladium-catalyzed mono-γ-arylation of 7-methoxy-4-methylcoumarin Tetrahedron Letters. 60: 151057. DOI: 10.1016/J.Tetlet.2019.151057 |
0.334 |
|
2018 |
Winters M, DuHadaway JB, Pham KN, Lewis-Ballester A, Badir S, Wai J, Sheikh E, Yeh SR, Prendergast GC, Muller AJ, Malachowski WP. Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase. European Journal of Medicinal Chemistry. 162: 455-464. PMID 30469041 DOI: 10.1016/J.Ejmech.2018.11.010 |
0.621 |
|
2018 |
Krasley AT, Malachowski WP, Terz HM, Tran Tien S. Catalytic Enantioselective Birch-Heck Sequence for the Synthesis of Tricyclic Structures with All-Carbon Quaternary Stereocenters. Organic Letters. PMID 29561159 DOI: 10.1021/Acs.Orglett.8B00196 |
0.4 |
|
2017 |
Prendergast GC, Malachowski WP, DuHadaway JB, Muller AJ. Discovery of IDO1 Inhibitors: From Bench to Bedside. Cancer Research. 77: 6795-6811. PMID 29247038 DOI: 10.1158/0008-5472.Can-17-2285 |
0.404 |
|
2015 |
Malachowski WP, Winters M, DuHadaway JB, Lewis-Ballester A, Badir S, Wai J, Rahman M, Sheikh E, LaLonde JM, Yeh SR, Prendergast GC, Muller AJ. O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1. European Journal of Medicinal Chemistry. 108: 564-576. PMID 26717206 DOI: 10.1016/J.Ejmech.2015.12.028 |
0.628 |
|
2015 |
Burke SJ, Malachowski WP, Mehta SK, Appenteng R. The enantioselective construction of tetracyclic diterpene skeletons with Friedel-Crafts alkylation and palladium-catalyzed cycloalkenylation reactions. Organic & Biomolecular Chemistry. 13: 2726-44. PMID 25598198 DOI: 10.1039/C4Ob02489C |
0.575 |
|
2015 |
Krasley AT, Malachowski WP. The first report of Lewis acid reagents in the intramolecular Rauhut-Currier reaction Tetrahedron Letters. 56: 6073-6076. DOI: 10.1016/J.Tetlet.2015.09.069 |
0.327 |
|
2014 |
Ross TM, Burke S, Malachowski WP. Enantioselective synthesis of decalin structures with all-carbon quaternary centers via one-pot sequential Cope/Rauhut-Currier reaction. Tetrahedron Letters. 55: 4616-4618. PMID 25125710 DOI: 10.1016/J.Tetlet.2014.06.085 |
0.561 |
|
2010 |
Qiao Y, Kumar S, Malachowski WP. Enantioselective synthesis of bicarbocyclic structures with an all-carbon quaternary stereocenter through sequential cross metathesis and intramolecular Rauhut-Currier reaction Tetrahedron Letters. 51: 2636-2638. DOI: 10.1016/J.Tetlet.2010.03.026 |
0.352 |
|
2010 |
MALACHOWSKI WP, COWARD JK. ChemInform Abstract: The Chemistry of Phosphapeptides: Investigations on the Synthesis of Phosphonamidate, Phosphonate, and Phosphinate Analogues of Glutamyl-. gamma.-glutamate. Cheminform. 26: no-no. DOI: 10.1002/chin.199525214 |
0.548 |
|
2008 |
Kumar S, Jaller D, Patel B, LaLonde JM, DuHadaway JB, Malachowski WP, Prendergast GC, Muller AJ. Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase Journal of Medicinal Chemistry. 51: 4968-4977. PMID 18665584 DOI: 10.1021/Jm800512Z |
0.472 |
|
2008 |
Kumar S, Malachowski WP, DuHadaway JB, LaLonde JM, Carroll PJ, Jaller D, Metz R, Prendergast GC, Muller AJ. Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors. Journal of Medicinal Chemistry. 51: 1706-18. PMID 18318466 DOI: 10.1021/Jm7014155 |
0.44 |
|
2008 |
Banerjee T, Duhadaway JB, Gaspari P, Sutanto-Ward E, Munn DH, Mellor AL, Malachowski WP, Prendergast GC, Muller AJ. A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase. Oncogene. 27: 2851-7. PMID 18026137 DOI: 10.1038/Sj.Onc.1210939 |
0.404 |
|
2007 |
Malachowski WP, Paul T, Phounsavath S. The enantioselective synthesis of (-)-lycoramine with the Birch-Cope sequence. The Journal of Organic Chemistry. 72: 6792-6. PMID 17676911 DOI: 10.1021/Jo070976V |
0.39 |
|
2007 |
Paul T, Malachowski WP, Lee J. Exploration of the enantioselective Birch-Cope sequence for the synthesis of carbocyclic quaternary stereocenters. The Journal of Organic Chemistry. 72: 930-7. PMID 17253813 DOI: 10.1021/Jo0621423 |
0.385 |
|
2006 |
Paul T, Malachowski WP, Lee J. The enantioselective Birch-Cope sequence for the synthesis of carbocyclic quaternary stereocenters. Application to the synthesis of (+)-mesembrine. Organic Letters. 8: 4007-10. PMID 16928060 DOI: 10.1021/Ol0615228 |
0.384 |
|
2006 |
Gaspari P, Banerjee T, Malachowski WP, Muller AJ, Prendergast GC, DuHadaway J, Bennett S, Donovan AM. Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors. Journal of Medicinal Chemistry. 49: 684-92. PMID 16420054 DOI: 10.1021/Jm0508888 |
0.462 |
|
2005 |
Muller AJ, Malachowski WP, Prendergast GC. Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors. Expert Opinion On Therapeutic Targets. 9: 831-49. PMID 16083346 DOI: 10.1517/14728222.9.4.831 |
0.423 |
|
2005 |
Malachowski WP, Metz R, Prendergast GC, Muller AJ. A new cancer immunosuppression target: Indoleamine 2,3-dioxygenase (IDO). A review of the IDO mechanism, inhibition and therapeutic applications Drugs of the Future. 30: 897-909. DOI: 10.1358/Dof.2005.030.09.918200 |
0.395 |
|
2005 |
Broadrup RL, Wang B, Malachowski WP. A general strategy for the synthesis of azapeptidomimetic lactams Tetrahedron. 61: 10277-10284. DOI: 10.1016/J.Tet.2005.08.029 |
0.389 |
|
2004 |
Malachowski WP, Banerji M. Sequential Birch reduction-allylation and Cope rearrangement of o-anisic acid derivatives Tetrahedron Letters. 45: 8183-8185. DOI: 10.1016/J.Tetlet.2004.09.025 |
0.36 |
|
2002 |
Malachowski WP, Tie C, Wang K, Broadrup RL. The synthesis of azapeptidomimetic beta-lactam molecules as potential protease inhibitors. The Journal of Organic Chemistry. 67: 8962-9. PMID 12467415 DOI: 10.1021/Jo026280D |
0.344 |
|
1997 |
Schultz AG, Malachowski WP, Pan Y. Asymmetric total synthesis of (+)-apovincamine and a formal synthesis of (+)-vincamine. Demonstration of a practical 'asymmetric linkage' between aromatic carboxylic acids and chiral acyclic substrates Journal of Organic Chemistry. 62: 1223-1229. DOI: 10.1021/Jo961603P |
0.553 |
|
1994 |
Malachowski WP, Coward JK. The Chemistry of Phosphapeptides: Investigations on the Synthesis of Phosphonamidate, Phosphonate, and Phosphinate Analogs of Glutamyl-.gamma.-glutamate Journal of Organic Chemistry. 59: 7625-7634. DOI: 10.1021/Jo00104A017 |
0.576 |
|
1994 |
Malachowski WP, Coward JK. The chemistry of phosphapeptides: Formation of functionalized phosphonochloridates under mild conditions and their reaction with alcohols and amines Journal of Organic Chemistry. 59: 7616-7624. DOI: 10.1021/Jo00104A016 |
0.514 |
|
1994 |
Malachowski WP, Coward JK. The chemistry of phosphapeptides: Investigations on the synthesis of phosphonamidate, phosphonate, and phosphinate analogues of glutamyl-γ-glutamate Journal of Organic Chemistry. 59: 7625-7634. |
0.552 |
|
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