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Eugen C. Buehler, Ph.D. - Publications

Affiliations: 
2003 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Intelligent Systems: Machine Learning, Information Systems: Computational Biology and Bioinformatics
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kharat SS, Ding X, Swaminathan D, Suresh A, Singh M, Sengodan SK, Burkett S, Marks H, Pamala C, He Y, Fox SD, Buehler EC, Muegge K, Martin SE, Sharan SK. Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability. Science Signaling. 13. PMID 32817374 DOI: 10.1126/Scisignal.Aba8091  0.34
2018 Martin S, Chiramel AI, Schmidt ML, Chen YC, Whitt N, Watt A, Dunham EC, Shifflett K, Traeger S, Leske A, Buehler E, Martellaro C, Brandt J, Wendt L, Müller A, et al. A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle. Genome Medicine. 10: 58. PMID 30081931 DOI: 10.1186/S13073-018-0570-1  0.355
2018 Baird TD, Cheng KC, Chen YC, Buehler E, Martin SE, Inglese J, Hogg JR. ICE1 promotes the link between splicing and nonsense-mediated mRNA decay. Elife. 7. PMID 29528287 DOI: 10.7554/Elife.33178  0.414
2017 Sivan G, Ormanoglu P, Buehler EC, Martin SE, Moss B. Erratum for Sivan et al., "Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L(-)C7L(-) Mutant". Mbio. 8. PMID 29089434 DOI: 10.1128/Mbio.01735-17  0.365
2017 Inwood S, Buehler E, Betenbaugh M, Lal M, Shiloach J. Identifying HIPK1 as target of miR-22-3p enhancing recombinant protein production from HEK 293 cell by using microarray and HTP siRNA screen. Biotechnology Journal. PMID 28987030 DOI: 10.1002/Biot.201700342  0.413
2017 Welsbie DS, Mitchell KL, Jaskula-Ranga V, Sluch VM, Yang Z, Kim J, Buehler E, Patel A, Martin SE, Zhang PW, Ge Y, Duan Y, Fuller J, Kim BJ, Hamed E, et al. Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons. Neuron. 94: 1142-1154.e6. PMID 28641113 DOI: 10.1016/J.Neuron.2017.06.008  0.354
2017 Panda D, Fernandez DJ, Lal M, Buehler E, Moss B. Triad of human cellular proteins, IRF2, FAM111A, and RFC3, restrict replication of orthopoxvirus SPI-1 host-range mutants. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320935 DOI: 10.1073/Pnas.1700678114  0.431
2017 Li MM, Lau Z, Cheung P, Aguilar EG, Schneider WM, Bozzacco L, Molina H, Buehler E, Takaoka A, Rice CM, Felsenfeld DP, MacDonald MR. TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP). Plos Pathogens. 13: e1006145. PMID 28060952 DOI: 10.1371/Journal.Ppat.1006145  0.387
2016 Mehedi M, McCarty T, Martin SE, Le Nouën C, Buehler E, Chen YC, Smelkinson M, Ganesan S, Fischer ER, Brock LG, Liang B, Munir S, Collins PL, Buchholz UJ. Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread. Plos Pathogens. 12: e1006062. PMID 27926942 DOI: 10.1371/Journal.Ppat.1006062  0.358
2016 Xiao S, Chen YC, Buehler E, Mandal S, Mandal A, Betenbaugh M, Park MH, Martin S, Shiloach J. Genome-scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells. Biotechnology and Bioengineering. PMID 27215166 DOI: 10.1002/Bit.26017  0.375
2016 Dutta B, Azhir A, Merino LH, Guo Y, Revanur S, Madhamshettiwar PB, Germain RN, Smith JA, Simpson KJ, Martin SE, Buehler E, Fraser ID. Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data. Nature Communications. 7: 11214. PMID 26997126 DOI: 10.1038/Ncomms11214  0.307
2016 Grohar PJ, Kim S, Rangel Rivera GO, Sen N, Haddock S, Harlow ML, Maloney NK, Zhu J, O'Neill M, Jones TL, Huppi K, Grandin M, Gehlhaus K, Klumpp-Thomas CA, Buehler E, et al. Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma. Cell Reports. PMID 26776507 DOI: 10.1016/J.Celrep.2015.12.063  0.429
2016 Bogen D, Wei JS, Azorsa DO, Ormanoglu P, Buehler E, Guha R, Keller JM, Griner LAM, Ferrer M, Song YK, Liao H, Mendoza A, Gryder BE, Sindri S, He J, et al. Abstract B31: Combined siRNA and small molecule screening identifies Aurora B kinase as an effective target in MYCN-driven neuroblastoma Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B31  0.378
2015 Bogen D, Wei JS, Azorsa DO, Ormanoglu P, Buehler E, Guha R, Keller JM, Mathews Griner LA, Ferrer M, Song YK, Liao H, Mendoza A, Gryder BE, Sindri S, He J, et al. Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma. Oncotarget. PMID 26497213 DOI: 10.18632/Oncotarget.6208  0.372
2015 Sivan G, Ormanoglu P, Buehler EC, Martin SE, Moss B. Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L-C7L- Mutant. Mbio. 6. PMID 26242627 DOI: 10.1128/Mbio.01122-15  0.449
2015 Pasetto M, Antignani A, Ormanoglu P, Buehler E, Guha R, Pastan I, Martin SE, FitzGerald DJ. Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 112: E1135-42. PMID 25713356 DOI: 10.1073/Pnas.1501958112  0.432
2015 Grohar PJ, Kim S, Haddock S, Rivera GR, Harlow M, Maloney NK, Huppi K, Gehlhaus K, Grandin M, Klumpp-Thomas C, Buehler E, Helman LJ, Martin SE, Caplen NJ. Abstract 479: Inhibition of the splicing of the EWS-FLI1 fusion transcript reverses EWS-FLI1 driven oncogenic expression in Ewing sarcoma Cancer Research. 75: 479-479. DOI: 10.1158/1538-7445.Am2015-479  0.438
2014 Chung HY, Gu M, Buehler E, MacDonald MR, Rice CM. Seed sequence-matched controls reveal limitations of small interfering RNA knockdown in functional and structural studies of hepatitis C virus NS5A-MOBKL1B interaction. Journal of Virology. 88: 11022-33. PMID 25031347 DOI: 10.1128/Jvi.01582-14  0.323
2013 Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. Nature. 504: 291-5. PMID 24270810 DOI: 10.1038/Nature12748  0.337
2013 Sivan G, Martin SE, Myers TG, Buehler E, Szymczyk KH, Ormanoglu P, Moss B. Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 3519-24. PMID 23401514 DOI: 10.1073/Pnas.1300708110  0.445
2013 Bogen D, Buehler EC, Tuzmen P, Patidar R, Azorsa D, Song YK, Liao H, Tolman CA, Wen X, He JN, Martin SE, Wei JS, Khan J. Abstract 4398: Synthetic lethal siRNA screening to identify novel combinational therapies with Topotecan in neuroblastoma. Cancer Research. 73: 4398-4398. DOI: 10.1158/1538-7445.Am2013-4398  0.429
2013 McCalla A, Grohar P, Martin S, Buehler E, Kim S, Caplen N, Morris J, Kunkel M, Evans D, Monks A, Teicher B, Helman L. Abstract C222: The identification of kinase targets in Ewing sarcoma cell lines using RNAi and high-throughput investigational agents screens. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C222  0.403
2012 Buehler E, Chen YC, Martin S. C911: A bench-level control for sequence specific siRNA off-target effects. Plos One. 7: e51942. PMID 23251657 DOI: 10.1371/Journal.Pone.0051942  0.335
2012 Buehler E, Khan AA, Marine S, Rajaram M, Bahl A, Burchard J, Ferrer M. siRNA off-target effects in genome-wide screens identify signaling pathway members. Scientific Reports. 2: 428. PMID 22645644 DOI: 10.1038/Srep00428  0.405
2012 Marine S, Bahl A, Ferrer M, Buehler E. Common seed analysis to identify off-target effects in siRNA screens Journal of Biomolecular Screening. 17: 370-378. PMID 22086724 DOI: 10.1177/1087057111427348  0.379
2004 Buehler EC, Sachs JR, Shao K, Bagchi A, Ungar LH. The CRASSS plug-in for integrating annotation data with hierarchical clustering results. Bioinformatics (Oxford, England). 20: 3266-9. PMID 15201188 DOI: 10.1093/Bioinformatics/Bth362  0.46
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