| Year |
Citation |
Score |
| 2022 |
Wang H, Taouil A, Awwa M, Clement T, Zhu C, Kim J, Rendina D, Jayanetti K, Maharaj A, Wang L, Bogdan D, Pepe A, Kaczocha M, Ojima I. SAR study on Novel truxillic acid monoester-Based inhibitors of fatty acid binding proteins as Next-Generation antinociceptive agents. Bioorganic Chemistry. 129: 106184. PMID 36244323 DOI: 10.1016/j.bioorg.2022.106184 |
0.506 |
|
| 2020 |
Rong D, Wang C, Zhang X, Wei Y, Zhang M, Liu D, Farhan H, Momen Ali SA, Liu Y, Taouil A, Guo W, Wang Y, Ojima I, Yang S, Wang H. A novel taxane, difluorovinyl-ortataxel, effectively overcomes paclitaxel-resistance in breast cancer cells. Cancer Letters. PMID 32730778 DOI: 10.1016/J.Canlet.2020.06.025 |
0.345 |
|
| 2020 |
Lazzarini C, Haranahalli K, McCarthy JB, Mallamo J, Ojima I, Del Poeta M. Preclinical evaluation of acylhydrazone SB-AF-1002 as a novel broad-spectrum antifungal agent. Antimicrobial Agents and Chemotherapy. PMID 32601165 DOI: 10.1128/Aac.00946-20 |
0.324 |
|
| 2019 |
Wang C, Wang X, Sun Y, Taouil AK, Yan S, Botchkina GI, Ojima I. Design, synthesis and SAR study of 3rd-generation taxoids bearing 3-CH, 3-CFO and 3-CHFO groups at the C2-benzoate position. Bioorganic Chemistry. 95: 103523. PMID 31911305 DOI: 10.1016/J.Bioorg.2019.103523 |
0.395 |
|
| 2019 |
Carbonetti G, Converso C, Clement T, Wang C, Trotman L, Ojima I, Kaczocha M. Docetaxel/cabazitaxel and fatty acid binding protein 5 inhibitors produce synergistic inhibition of prostate cancer growth. The Prostate. PMID 31661167 DOI: 10.1002/Pros.23921 |
0.322 |
|
| 2019 |
Haranahalli K, Honda T, Ojima I. Recent progress in the strategic incorporation of fluorine into medicinally active compounds. Journal of Fluorine Chemistry. 217: 29-40. PMID 31537946 DOI: 10.1016/J.Jfluchem.2018.11.002 |
0.367 |
|
| 2019 |
Haranahalli K, Lazzarini C, Sun Y, Zambito J, Pathiranage S, McCarthy JB, Mallamo JP, Del Poeta M, Ojima I. SAR Studies on Aromatic Acylhydrazone-Based Inhibitors of Fungal Sphingolipid Synthesis as Next-Generation Antifungal Agents. Journal of Medicinal Chemistry. PMID 31369263 DOI: 10.1021/Acs.Jmedchem.9B01004 |
0.356 |
|
| 2018 |
Teng YG, Chien CW, Chiou WH, Honda T, Ojima I. Construction of Fused Tropone Systems Through Intramolecular Rh(I)-Catalyzed Carbonylative [2+2+2+1] Cycloadditon of Triynes. Frontiers in Chemistry. 6: 401. PMID 30250840 DOI: 10.3389/Fchem.2018.00401 |
0.71 |
|
| 2018 |
Chien CW, Teng YG, Honda T, Ojima I. Synthesis of Colchicinoids and Allocolchicinoids through Rh(I)-catalyzed [2+2+2+1] and [2+2+2] Cycloadditions of o-Phenylenetriynes with and without CO. The Journal of Organic Chemistry. PMID 30129760 DOI: 10.1021/Acs.Joc.8B01608 |
0.592 |
|
| 2018 |
Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, ... ... Ojima I, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. European Journal of Medicinal Chemistry. 154: 233-252. PMID 29803996 DOI: 10.1016/J.Ejmech.2018.04.050 |
0.321 |
|
| 2018 |
Jelínek M, Balušíková K, Daniel P, Němcová-Fürstová V, Kirubakaran P, Jaček M, Wei L, Wang X, Vondrášek J, Ojima I, Kovář J. Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel. Toxicology and Applied Pharmacology. PMID 29625142 DOI: 10.1016/J.Taap.2018.04.002 |
0.311 |
|
| 2018 |
Yang CH, Wang C, Ojima I, Horwitz SB. Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of β-Tubulin and the Multidrug Resistance Associated P-Glycoprotein. Journal of Natural Products. PMID 29517223 DOI: 10.1021/Acs.Jnatprod.7B01047 |
0.348 |
|
| 2018 |
Lazzarini C, Haranahalli K, Rieger R, Ananthula HK, Desai PB, Ashbaugh A, Linke MJ, Cushion MT, Ruzsicska B, Haley J, Ojima I, Del Poeta M. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrobial Agents and Chemotherapy. PMID 29507066 DOI: 10.1128/Aac.00156-18 |
0.359 |
|
| 2018 |
Ojima I, Wang X, Jing Y, Wang C. Quest for Efficacious Next-Generation Taxoid Anticancer Agents and Their Tumor-Targeted Delivery. Journal of Natural Products. PMID 29468872 DOI: 10.1021/Acs.Jnatprod.7B01012 |
0.418 |
|
| 2018 |
Seitz JD, Wang T, Vineberg JG, Honda T, Ojima I. Synthesis of a Next-Generation Taxoid by Rapid Methylation Amenable for 11C-Labeling. The Journal of Organic Chemistry. PMID 29441783 DOI: 10.1021/Acs.Joc.7B03284 |
0.804 |
|
| 2017 |
Wang T, Vineberg JG, Honda T, Ojima I. Design and synthesis of tumor-targeting theranostic drug conjugates for SPECT and PET imaging studies. Bioorganic Chemistry. 76: 458-467. PMID 29287255 DOI: 10.1016/J.Bioorg.2017.12.018 |
0.79 |
|
| 2017 |
Ojima I. Strategic Incorporation of Fluorine into Taxoid Anticancer Agents for Medicinal Chemistry and Chemical Biology Studies. Journal of Fluorine Chemistry. 198: 10-23. PMID 28824201 DOI: 10.1016/J.Jfluchem.2016.12.016 |
0.35 |
|
| 2017 |
Ahmad G, El Sadda R, Botchkina G, Ojima I, Egan J, Amiji M. Nanoemulsion Formulation of a Novel Taxoid DHA-SBT-1214 Inhibits Prostate Cancer Stem Cell-Induced Tumor Growth. Cancer Letters. PMID 28803993 DOI: 10.1016/J.Canlet.2017.08.004 |
0.329 |
|
| 2017 |
Ojima I, Awasthi D, Wei L, Haranahalli K. Strategic incorporation of fluorine in the drug discovery of new-generation antitubercular agents targeting bacterial cell division protein FtsZ. Journal of Fluorine Chemistry. 196: 44-56. PMID 28555087 DOI: 10.1016/J.Jfluchem.2016.07.020 |
0.388 |
|
| 2017 |
Jelinek M, Kabelova A, Sramek J, Seitz J, Ojima I, Kovar J. Differing Mechanisms of Death Induction by Fluorinated Taxane SB-T-12854 in Breast Cancer Cells. Anticancer Research. 37: 1581-1590. PMID 28373418 DOI: 10.21873/Anticanres.11488 |
0.547 |
|
| 2017 |
Zheng X, Wang C, Xing Y, Chen S, Meng T, You H, Ojima I, Dong Y. SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells. International Journal of Oncology. PMID 28197640 DOI: 10.3892/Ijo.2017.3871 |
0.322 |
|
| 2016 |
Islam MM, Hameed HM, Mugweru J, Chhotaray C, Wang C, Tan Y, Liu J, Li X, Tan S, Ojima I, Yew WW, Nuermberger E, Lamichhane G, Zhang T. Drug resistance mechanisms and novel drug targets for tuberculosis therapy. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 28117224 DOI: 10.1016/J.Jgg.2016.10.002 |
0.318 |
|
| 2016 |
Haranahalli K, Tong S, Ojima I. Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ. Bioorganic & Medicinal Chemistry. PMID 27189886 DOI: 10.1016/J.Bmc.2016.05.003 |
0.347 |
|
| 2016 |
Yang CH, Wang C, Ojima I, Horwitz SB. Abstract 1229: The next-generation taxanes, SB-T-1214 and SB-CST-10202, exhibit distinct inhibitory effects on photolabeling of β-tubulin from different eukaryotic sources Cancer Research. 76: 1229-1229. DOI: 10.1158/1538-7445.Am2016-1229 |
0.341 |
|
| 2016 |
Afrimzon E, Botchkina G, Zurgil N, Shafran Y, Sobolev M, Moshkov S, Ravid-Hermesh O, Ojima I, Deutsch M. Hydrogel microstructure live-cell array for multiplexed analyses of cancer stem cells, tumor heterogeneity and differential drug response at single-element resolution Lab On a Chip - Miniaturisation For Chemistry and Biology. 16: 1047-1062. DOI: 10.1039/C6Lc00014B |
0.344 |
|
| 2015 |
Ojima I, Lichtenthal B, Lee S, Wang C, Wang X. Taxane anticancer agents: a patent perspective. Expert Opinion On Therapeutic Patents. 1-20. PMID 26651178 DOI: 10.1517/13543776.2016.1111872 |
0.319 |
|
| 2015 |
Teng YH, Berger WT, Nesbitt NM, Kumar K, Balius TE, Rizzo RC, Tonge PJ, Ojima I, Swaminathan S. Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A. Bioorganic & Medicinal Chemistry. 23: 5489-95. PMID 26275678 DOI: 10.1016/J.Bmc.2015.07.040 |
0.723 |
|
| 2015 |
Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, et al. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. Mbio. 6. PMID 26106079 DOI: 10.1128/Mbio.00647-15 |
0.371 |
|
| 2015 |
Li W, Zheng S, Higgins M, Morra RP, Mendis AT, Chien CW, Ojima I, Mierke DF, Dinkova-Kostova AT, Honda T. New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase. Journal of Medicinal Chemistry. 58: 4738-48. PMID 25965897 DOI: 10.1021/Acs.Jmedchem.5B00393 |
0.605 |
|
| 2015 |
Seitz JD, Vineberg JG, Herlihy E, Park B, Melief E, Ojima I. Design, synthesis and biological evaluation of a highly-potent and cancer cell selective folate-taxoid conjugate. Bioorganic & Medicinal Chemistry. 23: 2187-94. PMID 25819334 DOI: 10.1016/J.Bmc.2015.02.057 |
0.812 |
|
| 2015 |
He Z, Schulz A, Wan X, Seitz J, Bludau H, Alakhova DY, Darr DB, Perou CM, Jordan R, Ojima I, Kabanov AV, Luxenhofer R. Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: preparation, in vitro and in vivo evaluation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 208: 67-75. PMID 25725361 DOI: 10.1016/J.Jconrel.2015.02.024 |
0.603 |
|
| 2015 |
Seitz JD, Vineberg JG, Wei L, Khan JF, Lichtenthal B, Lin CF, Ojima I. Design, Synthesis and Application of Fluorine-Labeled Taxoids as (19)F NMR Probes for the Metabolic Stability Assessment of Tumor-Targeted Drug Delivery Systems. Journal of Fluorine Chemistry. 171: 148-161. PMID 25722499 DOI: 10.1016/J.Jfluchem.2014.08.006 |
0.787 |
|
| 2015 |
Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG. Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The Journal of Biological Chemistry. 290: 8711-21. PMID 25666611 DOI: 10.1074/Jbc.M114.618447 |
0.637 |
|
| 2015 |
Vineberg JG, Wang T, Zuniga ES, Ojima I. Design, synthesis, and biological evaluation of theranostic vitamin-linker-taxoid conjugates. Journal of Medicinal Chemistry. 58: 2406-16. PMID 25654690 DOI: 10.1021/Jm5019115 |
0.794 |
|
| 2015 |
Zang Y, Ojima I. Pd-catalyzed asymmetric allylic amination with BOP ligands and its applications to the synthesis of fused polycyclic alkaloids Tetrahedron Letters. 56: 3288-3292. DOI: 10.1016/J.Tetlet.2015.01.047 |
0.573 |
|
| 2014 |
Matesanz R, Trigili C, RodrÃguez-Salarichs J, Zanardi I, Pera B, Nogales A, Fang WS, JÃmenez-Barbero J, Canales A, Barasoain I, Ojima I, DÃaz JF. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances. Bioorganic & Medicinal Chemistry. 22: 5078-90. PMID 25047938 DOI: 10.1016/J.Bmc.2014.05.048 |
0.305 |
|
| 2014 |
Rowehl RA, Burke S, Bialkowska AB, Pettet DW, Rowehl L, Li E, Antoniou E, Zhang Y, Bergamaschi R, Shroyer KR, Ojima I, Botchkina GI. Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. Plos One. 9: e99091. PMID 24921652 DOI: 10.1371/Journal.Pone.0099091 |
0.322 |
|
| 2014 |
Vineberg JG, Zuniga ES, Kamath A, Chen YJ, Seitz JD, Ojima I. Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy. Journal of Medicinal Chemistry. 57: 5777-91. PMID 24901491 DOI: 10.1021/Jm500631U |
0.804 |
|
| 2014 |
Knudson SE, Kumar K, Awasthi D, Ojima I, Slayden RA. In vitro-in vivo activity relationship of substituted benzimidazole cell division inhibitors with activity against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 94: 271-6. PMID 24746463 DOI: 10.1016/J.Tube.2014.03.007 |
0.312 |
|
| 2014 |
Park B, Awasthi D, Chowdhury SR, Melief EH, Kumar K, Knudson SE, Slayden RA, Ojima I. Design, synthesis and evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents. Bioorganic & Medicinal Chemistry. 22: 2602-12. PMID 24726304 DOI: 10.1016/J.Bmc.2014.03.035 |
0.646 |
|
| 2014 |
Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I. Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. Plos One. 9: e94200. PMID 24705380 DOI: 10.1371/Journal.Pone.0094200 |
0.707 |
|
| 2014 |
Ojima I, Kumar K, Awasthi D, Vineberg JG. Drug discovery targeting cell division proteins, microtubules and FtsZ. Bioorganic & Medicinal Chemistry. 22: 5060-77. PMID 24680057 DOI: 10.1016/J.Bmc.2014.02.036 |
0.798 |
|
| 2014 |
Moriwaki H, Resch D, Li H, Ojima I, Takeda R, Aceña JL, Soloshonok V. Inexpensive chemical method for preparation of enantiomerically pure phenylalanine. Amino Acids. 46: 945-52. PMID 24385244 DOI: 10.1007/S00726-013-1656-0 |
0.33 |
|
| 2014 |
Lin CF, Chien CW, Ojima I. Enantioselective Pd-catalyzed tandem allylic alkylation reaction using monodentate phosphoramidite ligands for the formal total synthesis of huperzine A Organic Chemistry Frontiers. 1: 1062-1066. DOI: 10.1039/C4Qo00180J |
0.727 |
|
| 2014 |
Ojima I, Kamath A, Seitz JD. Taxol, Taxoids, and Related Taxanes Natural Products in Medicinal Chemistry. 127-180. DOI: 10.1002/9783527676545.ch04 |
0.438 |
|
| 2013 |
Awasthi D, Kumar K, Knudson SE, Slayden RA, Ojima I. SAR studies on trisubstituted benzimidazoles as inhibitors of Mtb FtsZ for the development of novel antitubercular agents. Journal of Medicinal Chemistry. 56: 9756-70. PMID 24266862 DOI: 10.1021/Jm401468W |
0.341 |
|
| 2013 |
Botchkina GI, Zuniga ES, Rowehl RH, Park R, Bhalla R, Bialkowska AB, Johnson F, Golub LM, Zhang Y, Ojima I, Shroyer KR. Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24. Plos One. 8: e69884. PMID 24086245 DOI: 10.1371/Journal.Pone.0069884 |
0.781 |
|
| 2013 |
Seitz J, Vineberg JG, Zuniga ES, Ojima I. Fluorine-Containing Taxoid Anticancer Agents and Their Tumor-Targeted Drug Delivery. Journal of Fluorine Chemistry. 152: 157-165. PMID 23935213 DOI: 10.1016/J.Jfluchem.2013.05.013 |
0.798 |
|
| 2013 |
Kumar K, Awasthi D, Lee SY, Cummings JE, Knudson SE, Slayden RA, Ojima I. Benzimidazole-based antibacterial agents against Francisella tularensis. Bioorganic & Medicinal Chemistry. 21: 3318-26. PMID 23623254 DOI: 10.1016/J.Bmc.2013.02.059 |
0.714 |
|
| 2013 |
Zang Y, Ojima I. Pd-catalyzed asymmetric allylic etherification using chiral biphenol-based diphosphinite ligands and its application for the formal total synthesis of (-)-galanthamine. The Journal of Organic Chemistry. 78: 4013-8. PMID 23472673 DOI: 10.1021/Jo400355J |
0.57 |
|
| 2013 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. High throughput fluorescence displacement assay with NBD-stearate. Plos One. DOI: 10.1371/Journal.Pone.0050968.G008 |
0.6 |
|
| 2013 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Scheme demonstrating anandamide inactivation and FABP drug target. Plos One. DOI: 10.1371/Journal.Pone.0050968.G001 |
0.641 |
|
| 2013 |
Zheng S, Chowdhury A, Ojima I, Honda T. Microwave-assisted Diels-Alder reactions between Danishefsky's diene and derivatives of ethyl α-(hydroxymethyl)acrylate. Synthetic approach toward a biotinylated anti-inflammatory monocyclic cyanoenone Tetrahedron. 69: 2052-2055. DOI: 10.1016/J.Tet.2012.12.079 |
0.309 |
|
| 2013 |
Ojima I, Athan A, Commandeur C, Chiou WH. Amidocarbonylation, Cyclohydrocarbonylation, and Related Reactions Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. DOI: 10.1016/B978-0-12-409547-2.03980-9 |
0.784 |
|
| 2012 |
Kamath A, Ojima I. Advances in the chemistry of β-lactam and its medicinal applications. Tetrahedron. 68: 10640-10664. PMID 23264702 DOI: 10.1016/J.Tet.2012.07.090 |
0.335 |
|
| 2012 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. Plos One. 7: e50968. PMID 23236415 DOI: 10.1371/Journal.Pone.0050968 |
0.662 |
|
| 2012 |
Kuznetsova L, Sun L, Chen J, Zhao X, Seitz J, Das M, Li Y, Veith JM, Pera P, Bernacki RJ, Xia S, Horwitz SB, Ojima I. Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids. Journal of Fluorine Chemistry. 143: 177-188. PMID 23139432 DOI: 10.1016/J.Jfluchem.2012.07.007 |
0.798 |
|
| 2012 |
Ehrlichová M, Ojima I, Chen J, Václavíková R, N?mcová-Fürstová V, Vobo?ilová J, Simek P, Horský S, Sou?ek P, Ková? J, Brabec M, Gut I. Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 1035-48. PMID 22855252 DOI: 10.1007/S00210-012-0785-4 |
0.325 |
|
| 2012 |
Zheng S, Santosh Laxmi YR, David E, Dinkova-Kostova AT, Shiavoni KH, Ren Y, Zheng Y, Trevino I, Bumeister R, Ojima I, Wigley WC, Bliska JB, Mierke DF, Honda T. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents. Journal of Medicinal Chemistry. 55: 4837-46. PMID 22533790 DOI: 10.1021/Jm3003922 |
0.308 |
|
| 2012 |
Ojima I, Zuniga ES, Berger WT, Seitz JD. Tumor-targeting drug delivery of new-generation taxoids. Future Medicinal Chemistry. 4: 33-50. PMID 22168163 DOI: 10.4155/Fmc.11.167 |
0.799 |
|
| 2012 |
Ojima I, Delaloge F. Syntheses of Norstatine, Its Analogs, and Dipeptide Isosteres by Means of β-Lactam Synthon Method. Methods in Molecular Medicine. 23: 137-60. PMID 21380896 DOI: 10.1385/0-89603-517-4:137 |
0.301 |
|
| 2012 |
Ehrlichova M, Vaclavikova R, Brynychova V, Nemcova V, Pecha V, Mrhalova M, Rob R, Ojima I, Gut I, Soucek P. 1045 Efficiency and Transport of Taxanes in Human Cancer Cell Lines and Solid Tumors European Journal of Cancer. 48: S252. DOI: 10.1016/S0959-8049(12)71656-8 |
0.308 |
|
| 2011 |
Lin CF, Ojima I. Formal enantioselective total synthesis of schulzeines A-C via Pd-catalyzed intramolecular asymmetric allylic amination. The Journal of Organic Chemistry. 76: 6240-9. PMID 21671593 DOI: 10.1021/Jo2009615 |
0.629 |
|
| 2011 |
Banerjee PS, Zuniga ES, Ojima I, Carrico IS. Targeted and armed oncolytic adenovirus via chemoselective modification. Bioorganic & Medicinal Chemistry Letters. 21: 4985-8. PMID 21669527 DOI: 10.1016/J.Bmcl.2011.05.039 |
0.765 |
|
| 2011 |
Awasthi D, Kumar K, Ojima I. Therapeutic potential of FtsZ inhibition: a patent perspective. Expert Opinion On Therapeutic Patents. 21: 657-79. PMID 21413908 DOI: 10.1517/13543776.2011.568483 |
0.335 |
|
| 2011 |
Shi C, Chien CW, Ojima I. Synthesis of chiral biphenol-based diphosphonite ligands and their application in palladium-catalyzed intermolecular asymmetric allylic amination reactions. Chemistry, An Asian Journal. 6: 674-80. PMID 21254441 DOI: 10.1002/Asia.201000697 |
0.61 |
|
| 2011 |
Kumar K, Awasthi D, Lee SY, Zanardi I, Ruzsicska B, Knudson S, Tonge PJ, Slayden RA, Ojima I. Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents. Journal of Medicinal Chemistry. 54: 374-81. PMID 21126020 DOI: 10.1021/Jm1012006 |
0.746 |
|
| 2011 |
Vobořilová J, Němcová-Fürstová V, Neubauerová J, Ojima I, Zanardi I, Gut I, Kovář J. Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells Investigational New Drugs. 29: 411-423. PMID 20013348 DOI: 10.1007/S10637-009-9368-8 |
0.314 |
|
| 2011 |
Ojima I. Tumor-targeting drug delivery of chemotherapeutic agents Pure and Applied Chemistry. 83: 1685-1698. DOI: 10.1351/Pac-Con-11-02-10 |
0.377 |
|
| 2011 |
Chien CW, Shi C, Lin CF, Ojima I. Enantioselective synthesis of 1-vinyltetrahydroisoquinolines via Pd-catalyzed intramolecular asymmetric allylic amination reactions Tetrahedron. 67: 6513-6523. DOI: 10.1016/J.Tet.2011.05.125 |
0.719 |
|
| 2011 |
Seitz J, Ojima I. Drug Conjugates with Polyunsaturated Fatty Acids Drug Delivery in Oncology: From Basic Research to Cancer Therapy. 3: 1323-1357. DOI: 10.1002/9783527634057.ch41 |
0.499 |
|
| 2010 |
Kumar K, Awasthi D, Berger WT, Tonge PJ, Slayden RA, Ojima I. Discovery of anti-TB agents that target the cell-division protein FtsZ. Future Medicinal Chemistry. 2: 1305-23. PMID 21339840 DOI: 10.4155/Fmc.10.220 |
0.668 |
|
| 2010 |
Sun L, Veith JM, Pera P, Bernacki RJ, Ojima I. Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel. Bioorganic & Medicinal Chemistry. 18: 7101-12. PMID 20800500 DOI: 10.1016/J.Bmc.2010.07.069 |
0.366 |
|
| 2010 |
Botchkina GI, Zuniga ES, Das M, Wang Y, Wang H, Zhu S, Savitt AG, Rowehl RA, Leyfman Y, Ju J, Shroyer K, Ojima I. New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. Molecular Cancer. 9: 192. PMID 20630067 DOI: 10.1186/1476-4598-9-192 |
0.789 |
|
| 2010 |
Chen S, Zhao X, Chen J, Chen J, Kuznetsova L, Wong SS, Ojima I. Mechanism-based tumor-targeting drug delivery system. Validation of efficient vitamin receptor-mediated endocytosis and drug release. Bioconjugate Chemistry. 21: 979-87. PMID 20429547 DOI: 10.1021/Bc9005656 |
0.706 |
|
| 2010 |
Botchkina GI, Ju J, Savitt AG, Rowehl RA, Zuniga E, Das M, Wang H, Zhu S, Ojima I. Abstract 3331: New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in colon and prostate CSCs Cancer Research. 70: 3331-3331. DOI: 10.1158/1538-7445.Am10-3331 |
0.784 |
|
| 2010 |
Ji JX, Chan ASC, Helmchen G, Kazmaier U, Förster S, Ojima I, Kaloko JJ, Chaterpaul SJ, Teng YHG, Lin CF, Mikami K, Aikawa K, Hoveyda AH, Malcolmson SJ, Meek SJ, et al. Asymmetric Carbon-Carbon Bond-Forming Reactions Catalytic Asymmetric Synthesis: Third Edition. 437-770. DOI: 10.1002/9780470584248.ch8 |
0.75 |
|
| 2009 |
DAS M, Zuniga E, Ojima I. Novel Taxoid-Based Tumor-Targeting Drug Conjugates. Chimica Oggi. 27: 54-56. PMID 21822353 |
0.805 |
|
| 2009 |
Ojima I. Medicinal chemistry at a crossroads: challenges and new possibilities. Future Medicinal Chemistry. 1: 401-3. PMID 21426118 DOI: 10.4155/Fmc.09.37 |
0.314 |
|
| 2009 |
Kaloko JJ, Teng YH, Ojima I. One-step formation of fused tetracyclic skeletons from cyclohexene-diynes and carbon monoxide through Rh(I)-catalyzed [2 + 2 + 2 + 1] cycloaddition reaction. Chemical Communications (Cambridge, England). 4569-71. PMID 19617986 DOI: 10.1039/B909781C |
0.787 |
|
| 2009 |
Chiou WH, Lin GH, Hsu CC, Chaterpaul SJ, Ojima I. Efficient syntheses of crispine A and harmicine by RH-catalyzed cyclohydrocarbonylation. Organic Letters. 11: 2659-62. PMID 19456145 DOI: 10.1021/Ol900702T |
0.789 |
|
| 2009 |
Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I. Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin. Bioorganic & Medicinal Chemistry Letters. 19: 3300-4. PMID 19423340 DOI: 10.1016/J.Bmcl.2009.04.070 |
0.702 |
|
| 2009 |
Sun L, Simmerling C, Ojima I. Recent advances in the study of the bioactive conformation of taxol. Chemmedchem. 4: 719-31. PMID 19360801 DOI: 10.1002/Cmdc.200900044 |
0.331 |
|
| 2009 |
Ojima I, Das M. Recent advances in the chemistry and biology of new generation taxoids. Journal of Natural Products. 72: 554-65. PMID 19239240 DOI: 10.1021/Np8006556 |
0.634 |
|
| 2009 |
Gut I, Vaclavikova R, Ehrlichova M, Ojima I, Otova B, Hrdy J, Kovar J, Voborilova J, Nemcova V, Zanardi I. Abstract B9: Role of disposition, transport, in vitro efficiency and expression of relevant genes in the effects of novel taxanes on subcutaneous lymphoma in Sprague‐Dawley/Cub rats Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B9 |
0.358 |
|
| 2009 |
Gut I, Ehrlichova M, Vaclavikova R, Ojima I, Simek P. Abstract A147: Novel fluorinated taxane SB‐T‐12854 active in drug‐resistant and sensitive cell lines: Human, pig, rat metabolism, cell transport, and effects on cell cycle Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A147 |
0.305 |
|
| 2009 |
Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I. ChemInform Abstract: Novel C-Seco-Taxoids Possessing High Potency Against Paclitaxel-Resistant Cancer Cell Lines Overexpressing Class III β-Tubulin. Cheminform. 40. DOI: 10.1002/chin.200944181 |
0.67 |
|
| 2009 |
Pepe A, Kuznetsova L, Sun L, Ojima I. Fluoro-Taxoid Anticancer Agents Fluorine in Medicinal Chemistry and Chemical Biology. 117-139. DOI: 10.1002/9781444312096.ch5 |
0.633 |
|
| 2009 |
Ojima I, Li Z, Zhu J. Recent Advances in the Hydrosilylation and Related Reactions Patai's Chemistry of Functional Groups. 1687-1792. DOI: 10.1002/9780470682531.Pat0191 |
0.331 |
|
| 2009 |
Ojima I, Das M, Zuniga E. Novel taxoid-based tumour-targeting drug conjugates Chimica Oggi. 27: 54-56. |
0.788 |
|
| 2008 |
Chiou WH, Schoenfelder A, Mann A, Ojima I. Application of Rhodium-Catalyzed Cyclohydrocarbonylation to the Syntheses of Enantiopure Homokainoids. Pure and Applied Chemistry. Chimie Pure Et Appliquee. 80: 1019-1024. PMID 19693284 DOI: 10.1351/Pac200880051019 |
0.61 |
|
| 2008 |
Chen J, Chen S, Zhao X, Kuznetsova LV, Wong SS, Ojima I. Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery. Journal of the American Chemical Society. 130: 16778-85. PMID 19554734 DOI: 10.1021/Ja805570F |
0.714 |
|
| 2008 |
Kuznetsova LV, Pepe A, Ungureanu IM, Pera P, Bernacki RJ, Ojima I. Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids. Journal of Fluorine Chemistry. 129: 817-828. PMID 19448839 DOI: 10.1016/J.Jfluchem.2008.05.013 |
0.708 |
|
| 2008 |
Sun L, Geng X, Geney R, Li Y, Simmerling C, Li Z, Lauher JW, Xia S, Horwitz SB, Veith JM, Pera P, Bernacki RJ, Ojima I. Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids. The Journal of Organic Chemistry. 73: 9584-93. PMID 18975909 DOI: 10.1021/Jo801713Q |
0.805 |
|
| 2008 |
Respicio L, Nair PA, Huang Q, Anil B, Tracz S, Truglio JJ, Kisker C, Raleigh DP, Ojima I, Knudson DL, Tonge PJ, Slayden RA. Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery. Tuberculosis (Edinburgh, Scotland). 88: 420-9. PMID 18479968 DOI: 10.1016/J.Tube.2008.03.001 |
0.327 |
|
| 2008 |
Ojima I, Chen J, Sun L, Borella CP, Wang T, Miller ML, Lin S, Geng X, Kuznetsova L, Qu C, Gallager D, Zhao X, Zanardi I, Xia S, Horwitz SB, et al. Design, synthesis, and biological evaluation of new-generation taxoids. Journal of Medicinal Chemistry. 51: 3203-21. PMID 18465846 DOI: 10.1021/Jm800086E |
0.798 |
|
| 2008 |
Ojima I. Modern natural products chemistry and drug discovery. Journal of Medicinal Chemistry. 51: 2587-8. PMID 18393400 DOI: 10.1021/Jm701291U |
0.303 |
|
| 2008 |
Xu H, Sullivan TJ, Sekiguchi J, Kirikae T, Ojima I, Stratton CF, Mao W, Rock FL, Alley MR, Johnson F, Walker SG, Tonge PJ. Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus. Biochemistry. 47: 4228-36. PMID 18335995 DOI: 10.1021/Bi800023A |
0.317 |
|
| 2008 |
Ojima I. Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads. Accounts of Chemical Research. 41: 108-19. PMID 17663526 DOI: 10.1021/Ar700093F |
0.387 |
|
| 2007 |
Chiou WH, Schoenfelder A, Sun L, Mann A, Ojima I. Rhodium-catalyzed cyclohydrocarbonylation approach to the syntheses of enantiopure homokainoids. The Journal of Organic Chemistry. 72: 9418-25. PMID 17999516 DOI: 10.1021/Jo070942N |
0.619 |
|
| 2007 |
Huang Q, Tonge PJ, Slayden RA, Kirikae T, Ojima I. FtsZ: a novel target for tuberculosis drug discovery. Current Topics in Medicinal Chemistry. 7: 527-43. PMID 17346197 DOI: 10.2174/156802607780059790 |
0.363 |
|
| 2007 |
Chiou WH, Mizutani N, Ojima I. Highly efficient synthesis of azabicyclo[x.y.0]alkane amino acids and congeners by means of Rh-catalyzed cyclohydrocarbonylation. The Journal of Organic Chemistry. 72: 1871-82. PMID 17346029 DOI: 10.1021/Jo061692Y |
0.628 |
|
| 2007 |
Shi C, Ojima I. Asymmetric synthesis of 1-vinyltetrahydroisoquinoline through Pd-catalyzed intramolecular allylic amination Tetrahedron. 63: 8563-8570. DOI: 10.1016/J.Tet.2007.04.097 |
0.326 |
|
| 2007 |
Ojima I, Kuznetsova LV, Sun L. Organofluorine chemistry at the biomedical interface: A case study on fluoro-taxoid anticancer agents Acs Symposium Series. 949: 288-304. |
0.475 |
|
| 2006 |
Gut I, Ojima I, Vaclavikova R, Simek P, Horsky S, Linhart I, Soucek P, Kondrova E, Kuznetsova LV, Chen J. Metabolism of new-generation taxanes in human, pig, minipig and rat liver microsomes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 36: 772-92. PMID 16971343 DOI: 10.1080/00498250600829220 |
0.527 |
|
| 2006 |
Chapsal BD, Ojima I. Total synthesis of enantiopure (+)-gamma-lycorane using highly efficient Pd-catalyzed asymmetric allylic alkylation. Organic Letters. 8: 1395-8. PMID 16562900 DOI: 10.1021/Ol060181V |
0.796 |
|
| 2006 |
Huang Q, Kirikae F, Kirikae T, Pepe A, Amin A, Respicio L, Slayden RA, Tonge PJ, Ojima I. Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents. Journal of Medicinal Chemistry. 49: 463-6. PMID 16420032 DOI: 10.1021/Jm050920Y |
0.595 |
|
| 2006 |
Kuznetsova L, Chen J, Sun L, Wu X, Pepe A, Veith JM, Pera P, Bernacki RJ, Ojima I. Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents. Bioorganic & Medicinal Chemistry Letters. 16: 974-7. PMID 16298526 DOI: 10.1016/J.Bmcl.2005.10.089 |
0.772 |
|
| 2006 |
Ojima I, Chapsal B. Total Synthesis of (+)-γ-Lycorane Synfacts. 2006: 0864-0864. DOI: 10.1055/s-2006-942051 |
0.768 |
|
| 2006 |
Chapsal BD, Hua Z, Ojima I. Catalytic asymmetric transformations with fine-tunable biphenol-based monodentate ligands Tetrahedron Asymmetry. 17: 642-657. DOI: 10.1016/J.Tetasy.2005.12.035 |
0.779 |
|
| 2005 |
Geney R, Chen J, Ojima I. Recent advances in the new generation taxane anticancer agents. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 1: 125-39. PMID 16787308 DOI: 10.2174/1573406053175292 |
0.811 |
|
| 2005 |
Bennacer B, Fujiwara M, Lee SY, Ojima I. Silicon-initiated carbonylative carbotricyclization and [2+2+2+1] cycloaddition of enediynes catalyzed by rhodium complexes. Journal of the American Chemical Society. 127: 17756-67. PMID 16351104 DOI: 10.1021/Ja054221M |
0.744 |
|
| 2005 |
Chen J, Jaracz S, Zhao X, Chen S, Ojima I. Antibody-cytotoxic agent conjugates for cancer therapy. Expert Opinion On Drug Delivery. 2: 873-90. PMID 16296784 DOI: 10.1517/17425247.2.5.873 |
0.566 |
|
| 2005 |
Ehrlichova M, Vaclavikova R, Ojima I, Pepe A, Kuznetsova LV, Chen J, Truksa J, Kovar J, Gut I. Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 372: 95-105. PMID 16059735 DOI: 10.1007/S00210-005-1080-4 |
0.691 |
|
| 2005 |
Jaracz S, Chen J, Kuznetsova LV, Ojima I. Recent advances in tumor-targeting anticancer drug conjugates. Bioorganic & Medicinal Chemistry. 13: 5043-54. PMID 15955702 DOI: 10.1016/J.Bmc.2005.04.084 |
0.616 |
|
| 2005 |
Geney R, Sun L, Pera P, Bernacki RJ, Xia S, Horwitz SB, Simmerling CL, Ojima I. Use of the tubulin bound paclitaxel conformation for structure-based rational drug design. Chemistry & Biology. 12: 339-48. PMID 15797218 DOI: 10.1016/J.Chembiol.2005.01.004 |
0.8 |
|
| 2005 |
Ojima I, Borella CP, Wu X, Bounaud PY, Oderda CF, Sturm M, Miller ML, Chakravarty S, Chen J, Huang Q, Pera P, Brooks TA, Baer MR, Bernacki RJ. Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents. Journal of Medicinal Chemistry. 48: 2218-28. PMID 15771464 DOI: 10.1021/Jm049483Y |
0.786 |
|
| 2005 |
Chiou WH, Lee SY, Ojima I. Recent advances in cyclohydrocarbonylation reactions Canadian Journal of Chemistry. 83: 681-692. DOI: 10.1139/V05-035 |
0.789 |
|
| 2004 |
Bennacer B, Fujiwara M, Ojima I. Novel [2 + 2 + 2 + 1] cycloaddition of enediynes catalyzed by rhodium complexes. Organic Letters. 6: 3589-91. PMID 15387555 DOI: 10.1021/Ol048500A |
0.347 |
|
| 2004 |
Choi H, Hua Z, Ojima I. Highly enantioselective copper-catalyzed conjugate addition of diethylzinc to nitroalkenes. Organic Letters. 6: 2689-91. PMID 15281745 DOI: 10.1021/Ol0491282 |
0.636 |
|
| 2004 |
Miller ML, Roller EE, Wu X, Leece BA, Goldmacher VS, Chari RV, Ojima I. Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies. Bioorganic & Medicinal Chemistry Letters. 14: 4079-82. PMID 15225730 DOI: 10.1016/J.Bmcl.2004.05.027 |
0.578 |
|
| 2004 |
Geng X, Geney R, Pera P, Bernacki RJ, Ojima I. Design and synthesis of de novo cytotoxic alkaloids through mimicking taxoid skeleton. Bioorganic & Medicinal Chemistry Letters. 14: 3491-4. PMID 15177459 DOI: 10.1016/J.Bmcl.2004.04.060 |
0.788 |
|
| 2004 |
Minderman H, Brooks TA, O'Loughlin KL, Ojima I, Bernacki RJ, Baer MR. Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023. Cancer Chemotherapy and Pharmacology. 53: 363-9. PMID 15060738 DOI: 10.1007/S00280-003-0745-2 |
0.311 |
|
| 2004 |
Hua Z, Vassar VC, Choi H, Ojima I. New biphenol-based, fine-tunable monodentate phosphoramidite ligands for catalytic asymmetric transformations. Proceedings of the National Academy of Sciences of the United States of America. 101: 5411-6. PMID 15020764 DOI: 10.1073/Pnas.0307101101 |
0.612 |
|
| 2004 |
Wu X, Ojima I. Tumor specific novel taxoid-monoclonal antibody conjugates. Current Medicinal Chemistry. 11: 429-38. PMID 14965224 DOI: 10.2174/0929867043455963 |
0.563 |
|
| 2004 |
Kuznetsova L, Ungureanu IM, Pepe A, Zanardi I, Wu X, Ojima I. Trifluoromethyl- and difluoromethyl-β-lactams as useful building blocks for the synthesis of fluorinated amino acids, dipeptides, and fluoro-taxoids Journal of Fluorine Chemistry. 125: 487-500. DOI: 10.1016/J.Jfluchem.2003.12.001 |
0.739 |
|
| 2003 |
Hua Z, Vassar VC, Ojima I. Synthesis of new chiral monodentate phosphite ligands and their use in catalytic asymmetric hydrogenation. Organic Letters. 5: 3831-4. PMID 14535721 DOI: 10.1021/Ol035343R |
0.627 |
|
| 2003 |
Geng X, Miller ML, Lin S, Ojima I. Synthesis of novel C2-C3'N-linked macrocyclic taxoids by means of highly regioselective Heck macrocyclization. Organic Letters. 5: 3733-6. PMID 14507217 DOI: 10.1021/Ol0354627 |
0.574 |
|
| 2003 |
Ojima I, Geney R. 109881 Aventis. Current Opinion in Investigational Drugs (London, England : 2000). 4: 737-40. PMID 12901234 |
0.759 |
|
| 2003 |
Ojima I, Geney R. BMS-184476 Bristol-Myers Squibb. Current Opinion in Investigational Drugs (London, England : 2000). 4: 732-6. PMID 12901233 |
0.758 |
|
| 2003 |
Ojima I, Ferlini C. New insights into drug resistance in cancer. Chemistry & Biology. 10: 583-4. PMID 12890528 DOI: 10.1016/S1074-5521(03)00152-2 |
0.33 |
|
| 2003 |
Ferlini C, Ojima I, Distefano M, Gallo D, Riva A, Morazzoni P, Bombardelli E, Mancuso S, Scambia G. Second generation taxanes: from the natural framework to the challenge of drug resistance. Current Medicinal Chemistry. Anti-Cancer Agents. 3: 133-8. PMID 12678907 DOI: 10.2174/1568011033353489 |
0.372 |
|
| 2003 |
Ojima I, Tsai C, Tzamarioudaki M, Bonafoux D. The Hydroformylation Reaction Cheminform. 34. DOI: 10.1002/0471264180.Or056.01 |
0.311 |
|
| 2002 |
Mizutani N, Chiou WH, Ojima I. New and efficient synthesis of azabicyclo[4.4.0]alkane amino acids by Rh-catalyzed cyclohydrocarbonylation. Organic Letters. 4: 4575-8. PMID 12489933 DOI: 10.1021/Ol026782D |
0.616 |
|
| 2002 |
Ojima I, Geng X, Wu X, Qu C, Borella CP, Xie H, Wilhelm SD, Leece BA, Bartle LM, Goldmacher VS, Chari RV. Tumor-specific novel taxoid-monoclonal antibody conjugates. Journal of Medicinal Chemistry. 45: 5620-3. PMID 12477344 DOI: 10.1021/Jm025540G |
0.776 |
|
| 2002 |
Geney R, Ungureanu lM, Li D, Ojima I. Overcoming multidrug resistance in taxane chemotherapy. Clinical Chemistry and Laboratory Medicine. 40: 918-25. PMID 12435109 DOI: 10.1515/Cclm.2002.161 |
0.807 |
|
| 2002 |
Ojima I, Vu AT, Lee SY, McCullagh JV, Moralee AC, Fujiwara M, Hoang TH. Rhodium-catalyzed silylcarbocyclization (SiCaC) and carbonylative silylcarbocyclization (CO-SiCaC) reactions of enynes. Journal of the American Chemical Society. 124: 9164-74. PMID 12149021 DOI: 10.1021/Ja0258982 |
0.743 |
|
| 2002 |
Ojima I, Geney R, Ungureanu IM, Li D. Medicinal chemistry and chemical biology of new generation taxane antitumor agents. Iubmb Life. 53: 269-74. PMID 12121008 DOI: 10.1080/15216540212658 |
0.805 |
|
| 2002 |
Jordan MA, Ojima I, Rosas F, Distefano M, Wilson L, Scambia G, Ferlini C. Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis. Chemistry & Biology. 9: 93-101. PMID 11841942 DOI: 10.1016/S1074-5521(01)00097-7 |
0.335 |
|
| 2002 |
Chuang CY, Vassar VC, Ma Z, Geney R, Ojima I. Electronic effects on the regio- and enantioselectivity of the asymmetric aminohydroxylation of O-substituted 4-hydroxy-2-butenoates. Chirality. 14: 151-62. PMID 11835558 DOI: 10.1002/Chir.10050 |
0.782 |
|
| 2002 |
Ojima I, Geng X, Lin S, Pera P, Bernacki RJ. Design, synthesis and biological activity of novel C2-C3' N-Linked macrocyclic taxoids. Bioorganic & Medicinal Chemistry Letters. 12: 349-52. PMID 11814794 DOI: 10.1016/S0960-894X(01)00747-8 |
0.577 |
|
| 2002 |
Ojima I. New cyclization reactions in organic syntheses Pure and Applied Chemistry. 74: 159-166. DOI: 10.1351/Pac200274010159 |
0.361 |
|
| 2002 |
Ojima I, Moralee AC, Vassar VC. Topics in Catalysis. 19: 89-99. DOI: 10.1023/A:1013837417361 |
0.318 |
|
| 2001 |
Miller ML, Ojima I. Chemistry and chemical biology of taxane anticancer agents. Chemical Record (New York, N.Y.). 1: 195-211. PMID 11895119 DOI: 10.1002/Tcr.1008 |
0.409 |
|
| 2001 |
Chibale K, Ojima I, Haupt H, Geng X, Pera P, Bernacki RJ. Modulation of human mammary cell sensitivity to paclitaxel by new quinoline sulfonamides. Bioorganic & Medicinal Chemistry Letters. 11: 2457-60. PMID 11549446 DOI: 10.1016/S0960-894X(01)00462-0 |
0.604 |
|
| 2001 |
Vredenburg MR, Ojima I, Veith J, Pera P, Kee K, Cabral F, Sharma A, Kanter P, Greco WR, Bernacki RJ. Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance. Journal of the National Cancer Institute. 93: 1234-45. PMID 11504769 DOI: 10.1093/Jnci/93.16.1234 |
0.349 |
|
| 2001 |
Crabtree DV, Ojima I, Geng X, Adler AJ. Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site. Bioorganic & Medicinal Chemistry. 9: 1967-76. PMID 11504633 DOI: 10.1016/S0968-0896(01)00103-1 |
0.512 |
|
| 2001 |
Bonafoux D, Hua Z, Wang B, Ojima I. Design and synthesis of new fluorinated ligands for the rhodium-catalyzed hydroformylation of alkenes in supercritical CO2 and fluorous solvents Journal of Fluorine Chemistry. 112: 101-108. DOI: 10.1016/S0022-1139(01)00473-0 |
0.599 |
|
| 2000 |
Ferlini C, Distefano M, Pignatelli F, Lin S, Riva A, Bombardelli E, Mancuso S, Ojima I, Scambia G. Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors British Journal of Cancer. 83: 1762-1768. PMID 11104578 DOI: 10.1054/Bjoc.2000.1500 |
0.341 |
|
| 2000 |
Ojima I, Lin S, Slater JC, Wang T, Pera P, Bernacki RJ, Ferlini C, Scambia G. Syntheses and biological activity of C-3'-difluoromethyl-taxoids. Bioorganic & Medicinal Chemistry. 8: 1619-28. PMID 10976509 DOI: 10.1016/S0968-0896(00)00093-6 |
0.379 |
|
| 2000 |
Lin S, Geng X, Qu C, Tynebor R, Gallagher DJ, Pollina E, Rutter J, Ojima I. Synthesis of highly potent second-generation taxoids through effective kinetic resolution coupling of racemic beta-lactams with baccatins. Chirality. 12: 431-41. PMID 10824166 DOI: 10.1002/(Sici)1520-636X(2000)12:5/6<431::Aid-Chir24>3.0.Co;2-M |
0.566 |
|
| 2000 |
Lin S, Ojima I. Recent strategies in the development of taxane anticancer drugs Expert Opinion On Therapeutic Patents. 10: 869-889. DOI: 10.1517/13543776.10.6.869 |
0.381 |
|
| 2000 |
Ojima I, Lee SY. Rhodium-catalyzed novel carbonylative carbotricyclization of enediynes [8] Journal of the American Chemical Society. 122: 2385-2386. DOI: 10.1021/Ja993977G |
0.751 |
|
| 2000 |
Ojima I, Lin S, Inoue T, Miller ML, Borella CP, Geng X, Walsh JJ. Macrocycle formation by ring-closing metathesis. Application to the syntheses of novel macrocyclic taxoids Journal of the American Chemical Society. 122: 5343-5353. DOI: 10.1021/Ja000293W |
0.799 |
|
| 1999 |
Ojima I, Wang T, Miller ML, Lin S, Borella CP, Geng X, Pera P, Bernacki RJ. Synthesis and structure-activity relationships of new second-generation taxoids. Bioorganic & Medicinal Chemistry Letters. 9: 3423-8. PMID 10617084 DOI: 10.1016/S0960-894X(99)00629-0 |
0.803 |
|
| 1999 |
Ojima I, Chakravarty S, Inoue T, Lin S, He L, Horwitz SB, Kuduk SD, Danishefsky SJ. A common pharmacophore for cytotoxic natural products that stabilize microtubules Proceedings of the National Academy of Sciences of the United States of America. 96: 4256-4261. PMID 10200249 DOI: 10.1073/Pnas.96.8.4256 |
0.325 |
|
| 1999 |
Nakano M, Tominaga K, Saito S, Kirikae F, Lin S, Fumero CL, Ojima I, Kirikae T. Lipopolysaccharide- and paclitaxel (Taxol)-induced tolerance in murine peritoneal macrophages Innate Immunity. 5: 102-106. DOI: 10.1177/09680519990050011201 |
0.745 |
|
| 1999 |
Ojima I, Vidal ES. Extremely Regioselective Intramolecular Silylformylation of Bis(silylamino)alkynes Organometallics. 18: 5103-5107. DOI: 10.1021/Om9904549 |
0.318 |
|
| 1999 |
Ojima I, Vu AT, McCullagh JV, Kinoshita A. Rhodium-catalyzed intramolecular silylcarbotricyclization (SiCaT) of triynes [7] Journal of the American Chemical Society. 121: 3230-3231. DOI: 10.1021/Ja9815529 |
0.335 |
|
| 1999 |
Ojima I, Inoue T, Chakravarty S. Enantiopure fluorine-containing taxoids: Potent anticancer agents and versatile probes for biomedical problems Journal of Fluorine Chemistry. 97: 3-10. DOI: 10.1016/S0022-1139(99)00058-5 |
0.371 |
|
| 1998 |
Ojima I, Bounaud PY, Takeuchi C, Pera P, Bernacki RJ. New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells. Bioorganic & Medicinal Chemistry Letters. 8: 189-94. PMID 9871652 DOI: 10.1016/S0960-894X(97)10218-9 |
0.385 |
|
| 1998 |
Ojima I, Bounaud P, Oderda CF. Recent strategies for the treatment of multi-drug resistance in cancer cells Expert Opinion On Therapeutic Patents. 8: 1587-1598. DOI: 10.1517/13543776.8.12.1587 |
0.345 |
|
| 1998 |
Ojima I, Vidal ES. Rhodium-Catalyzed Cyclohydrocarbonylation: Application to the Synthesis of (+)-Prosopinine and (−)-Deoxoprosophylline† Journal of Organic Chemistry. 63: 7999-8003. DOI: 10.1021/Jo9815608 |
0.309 |
|
| 1998 |
Ojima I, Lin S, Chakravarty S, Fenoglio I, Park YH, Sun C, Appendino G, Pera P, Veith JM, Bernacki RJ. Syntheses and Structure−Activity Relationships of Novel Nor-seco Taxoids The Journal of Organic Chemistry. 63: 1637-1645. DOI: 10.1021/Jo971953R |
0.346 |
|
| 1998 |
Ojima I, Lin S. Efficient Asymmetric Syntheses of β-Lactams Bearing a Cyclopropane or an Epoxide Moiety and Their Application to the Syntheses of Novel Isoserines and Taxoids Journal of Organic Chemistry. 63: 224-225. DOI: 10.1021/Jo971908J |
0.314 |
|
| 1998 |
Ojima I, Zhu J, Vidal ES, Kass DF. Silylcarbocyclizations of 1,6-Diynes Journal of the American Chemical Society. 120: 6690-6697. DOI: 10.1021/Ja980907L |
0.303 |
|
| 1998 |
Ojima I, Iula DM, Tzamarioudaki M. Efficient syntheses of functionalized piperidines through extremely regioselective Rh-catalyzed cyclohydrocarbonylation of amido-ω,ω'-dienes Tetrahedron Letters. 39: 4599-4602. DOI: 10.1016/S0040-4039(98)00848-X |
0.354 |
|
| 1998 |
Ojima I, Wang H, Wang T, Ng EW. New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method Tetrahedron Letters. 39: 923-926. DOI: 10.1016/S0040-4039(97)10677-3 |
0.3 |
|
| 1998 |
Distefano M, Scambia G, Ferlini C, Gaggini C, De Vincenzo R, Riva A, Bombardelli E, Ojima I, Fattorossi A, Benedetti Panici P, Mancuso S. Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.Int. J. Cancer,72, 844–850 (1997) International Journal of Cancer. 76: 164-164. DOI: 10.1002/(Sici)1097-0215(19980330)76:1<164::Aid-Ijc25>3.0.Co;2-B |
0.33 |
|
| 1997 |
Ojima I, Slater JC. Synthesis of novel 3'-trifluoromethyl taxoids through effective kinetic resolution of racemic 4-CF3-beta-lactams with baccatins. Chirality. 9: 487-94. PMID 9329178 DOI: 10.1002/(Sici)1520-636X(1997)9:5/6<487::Aid-Chir15>3.0.Co;2-K |
0.319 |
|
| 1997 |
Distefano M, Scambia G, Ferlini C, Gaggini C, De Vincenzo R, Riva A, Bombardelli E, Ojima I, Fattorossi A, Panici PB, Mancuso S. Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells. International Journal of Cancer. 72: 844-50. PMID 9311603 DOI: 10.1002/(Sici)1097-0215(19970904)72:5<844::Aid-Ijc22>3.0.Co;2-7 |
0.34 |
|
| 1997 |
Ojima I, Kuduk SD, Pera P, Veith JM, Bernacki RJ. Synthesis and structure-activity relationships of nonaromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity. Journal of Medicinal Chemistry. 40: 279-85. PMID 9022794 DOI: 10.1021/Jm9606711 |
0.318 |
|
| 1997 |
Ojima I, Slater JC, Kuduk SD, Takeuchi CS, Gimi RH, Sun CM, Park YH, Pera P, Veith JM, Bernacki RJ. Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III. Journal of Medicinal Chemistry. 40: 267-78. PMID 9022793 DOI: 10.1021/Jm960563E |
0.354 |
|
| 1997 |
Ojima I, Slater JC, Pera P, Veith JM, Abouabdellah A, Bégué JP, Bernacki RJ. Synthesis and biological activity of novel 3'-trifluoromethyl taxoids Bioorganic and Medicinal Chemistry Letters. 7: 133-138. DOI: 10.1016/S0960-894X(96)00595-1 |
0.389 |
|
| 1996 |
Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ. Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells. Journal of Medicinal Chemistry. 39: 3889-96. PMID 8831755 DOI: 10.1021/Jm9604080 |
0.363 |
|
| 1996 |
Ojima I, Machnik D, Donovan RJ, Mneimne O. Silylcyclocarbonylation (SiCCa) of alkynylamines catalyzed by rhodium complexes Inorganica Chimica Acta. 251: 299-307. DOI: 10.1016/S0020-1693(97)82717-X |
0.324 |
|
| 1996 |
Ojima I, McCullagh JV, Shay WR. New cascade silylcarbocyclization (SiCaC) of enediynes Journal of Organometallic Chemistry. 521: 421-423. DOI: 10.1016/0022-328X(96)06359-0 |
0.301 |
|
| 1995 |
Sharma A, Straubinger RM, Ojima I, Bernacki RJ. Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice Journal of Pharmaceutical Sciences. 84: 1400-1404. PMID 8748320 DOI: 10.1002/Jps.2600841204 |
0.326 |
|
| 1995 |
Ojima I, Tzamarioudaki M, Eguchi M. New and Efficient Route to Pipecolic Acid Derivatives by Means of Rh-Catalyzed Intramolecular Cyclohydrocarbonylation Journal of Organic Chemistry. 60: 7078-7079. DOI: 10.1021/Jo00127A002 |
0.319 |
|
| 1995 |
Ojima I, Vidal E, Tzamarioudaki M, Matsuda I. Extremely Regioselective Intramolecular Silylformylation of Alkynes Journal of the American Chemical Society. 117: 6797-6798. DOI: 10.1021/Ja00130A027 |
0.325 |
|
| 1995 |
Ojima I, Ng EW, Sun CM. Novel route to hydroxy(keto)ethylene dipeptide isosteres through the reaction of N-tBOC-β-lactams with enolates Tetrahedron Letters. 36: 4547-4550. DOI: 10.1016/0040-4039(95)00825-W |
0.345 |
|
| 1994 |
Ojima I, Duclos O, Zucco M, Bissery MC, Combeau C, Vrignaud P, Riou JF, Lavelle F. Synthesis and structure-activity relationships of new antitumor taxoids. Effects of cyclohexyl substitution at the C-3' and/or C-2 of taxotere (docetaxel). Journal of Medicinal Chemistry. 37: 2602-8. PMID 7914541 DOI: 10.1021/Jm00042A013 |
0.333 |
|
| 1994 |
Ojima I, Fenoglio I, Park YH, Sun C, Appendino G, Pera P, Bernacki RJ. Synthesis and Structure-Activity Relationships of Novel Nor-Seco Analogs of Taxol and Taxotere Journal of Organic Chemistry. 59: 515-517. DOI: 10.1021/Jo00082A003 |
0.37 |
|
| 1994 |
Ojima I, Fenoglio I, Park YH, Pera P, Bernacki RJ. Synthesis and biological activity of 14-hydroxydocetaxel Bioorganic & Medicinal Chemistry Letters. 4: 1571-1576. DOI: 10.1016/S0960-894X(01)80568-0 |
0.335 |
|
| 1994 |
Ojima I, Duclos O, Kuduk SD, Sun CM, Slater JC, Lavelle F, Veith JM, Bernacki RJ. Synthesis and biological activity of 3′-alkyl- and 3′-alkenyl-3′-dephenyldocetaxels Bioorganic and Medicinal Chemistry Letters. 4: 2631-2634. DOI: 10.1016/S0960-894X(01)80298-5 |
0.369 |
|
| 1993 |
Ojima I, Sun CM, Zucco M, Park YH, Duclos O, Kuduk S. A highly efficient route to taxotere by the β-Lactam Synthon Method Tetrahedron Letters. 34: 4149-4152. DOI: 10.1016/S0040-4039(00)60514-2 |
0.344 |
|
| 1993 |
Ojima I, Donovan RJ, Eguchi M, Shay WR, Ingallina P, Korda A, Zeng Q. Silylformylation catalyzed by Rh and Rh-Co mixed metal complexes and its application to the synthesis of pyrrolizidine alkaloids Tetrahedron. 49: 5431-5444. DOI: 10.1016/S0040-4020(01)87260-4 |
0.321 |
|
| 1993 |
Zhang Z, Ojima I. Syntheses of nitrogen heterocycles by means of amine-directed carbonylation and hydrocarbonylation Journal of Organometallic Chemistry. 454: 281-289. DOI: 10.1016/0022-328X(93)83252-Q |
0.308 |
|
| 1992 |
Ojima I, Pei Y. Novel rearrangements of chiral 3-oxazolidinylazetidin-2-ones Tetrahedron Letters. 33: 887-890. DOI: 10.1016/S0040-4039(00)91567-3 |
0.343 |
|
| 1992 |
Ojima I, Habus I, Zhao M, Zucco M, Park YH, Sun CM, Brigaud T. New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of β-lactam synthon method Tetrahedron. 48: 6985-7012. DOI: 10.1016/S0040-4020(01)91210-4 |
0.323 |
|
| 1992 |
Ojima I, Hoon Park Y, Ming Sun C, Brigaud T, Zhao M. New and efficient routes to norstatine and its analogs with high enantiomeric purity by β-Lactam Synthon Method Tetrahedron Letters. 33: 5737-5740. DOI: 10.1016/0040-4039(92)89019-9 |
0.305 |
|
| 1991 |
Ojima I, Korda A, Shay WR. New synthesis of nitrogen heterocycles through amide-directed hydrocarbonylation of alkenamides catalyzed by rhodium complexes Journal of Organic Chemistry. 56: 2024-2030. DOI: 10.1021/Jo00006A013 |
0.306 |
|
| 1991 |
Ojima I, Habus I, Zhao M, Georg GI, Jayasinghe LR. Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R,3S)-3-phenylisoserine, and its analogues via chiral 3-hydroxy-4-aryl-β-lactams through chiral ester enolate-imine cyclocondensation Journal of Organic Chemistry. 56: 1681-1683. DOI: 10.1021/Jo00005A003 |
0.316 |
|
| 1991 |
Ojima I. Design and synthesis of novel trifluoromethyl-containing peptides and their use as enzyme inhibitors Journal of Fluorine Chemistry. 54: 187. DOI: 10.1016/S0022-1139(00)83697-0 |
0.3 |
|
| 1991 |
Ojima I, Zhang Z. Amide-directed hydrocarbonylation of N-alkenylamides and α-alkenyllactams Journal of Organometallic Chemistry. 417: 253-276. DOI: 10.1016/0022-328X(91)80177-L |
0.33 |
|
| 1990 |
Ojima I. Chapter IV.1 New Carbonylations by Means of Transition Metal Catalysts Studies in Surface Science and Catalysis. 54: 301-321. DOI: 10.1016/S0167-2991(08)60046-4 |
0.31 |
|
| 1990 |
Ojima I, Pei Y. Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam. Tetrahedron Letters. 31: 977-980. DOI: 10.1016/S0040-4039(00)94407-1 |
0.312 |
|
| 1989 |
Ojima I, Korda A. New routes to nitrogen heterocycles through intramolecular amidocarbonylation of alkenamides catalyzed by rhodium complexes Tetrahedron Letters. 30: 6283-6286. DOI: 10.1016/S0040-4039(01)93873-0 |
0.343 |
|
| 1987 |
Brandstadter SM, Ojima I, Herai K. Reactions of ketene silyl acetals with imine-complexes of titanium tetrachloride. New and convenient routes to 5,6-dihydro-2-pyridones and 5-amino-2-alkenoates Tetrahedron Letters. 28: 613-616. DOI: 10.1016/S0040-4039(00)95794-0 |
0.331 |
|
| 1985 |
Ojima I, Yamato T, Nakahashi K. Synthesis of novel chiral bisazetidines by the hydroalane reduction of bis-beta-lactams Tetrahedron Letters. 26: 2035-2038. DOI: 10.1016/S0040-4039(00)94772-5 |
0.307 |
|
| 1984 |
Ojima I. Homogeneous asymmetric catalysis by means of chiral rhodium complexes Pure and Applied Chemistry. 56: 99-110. DOI: 10.1351/Pac198456010099 |
0.319 |
|
| 1984 |
Fuchikami T, Ojima I. Transition-metal complex catalyzed polyfluoroalkylation. II. Novel and convenient route to 3-polyfluoroalkylprop-1-enes through the reaction of polyfluoroalkyl halides with allylsilanes Tetrahedron Letters. 25: 307-308. DOI: 10.1016/S0040-4039(00)99869-1 |
0.308 |
|
| 1984 |
Ojima I, Fuchikami T, Yatabe M. The reactions of hydrosilanes with trifluoropropene and pentafluorostyrene catalyzed by ruthenium, rhodium and palladium complexes Journal of Organometallic Chemistry. 260: 335-346. DOI: 10.1016/S0022-328X(00)99483-X |
0.306 |
|
| 1983 |
Hirai K, Ojima I. Coupling reactions of vinylketene silyl acetals promoted by titanium tetrachloride Tetrahedron Letters. 24: 785-788. DOI: 10.1016/S0040-4039(00)81527-0 |
0.303 |
|
| 1983 |
Fuchikami T, Ojima I. Direct perfluoroalkylation of functionalized benzenes with perfluoroalkyl halides and copper bronze Journal of Fluorine Chemistry. 22: 541-556. DOI: 10.1016/S0022-1139(00)81229-4 |
0.309 |
|
| 1982 |
OJIMA I, HATANAKA N. Journal of Synthetic Organic Chemistry, Japan. 40: 209-217. DOI: 10.5059/Yukigoseikyokaishi.40.209 |
0.305 |
|
| 1982 |
Fuchikami T, Ojima I. New and direct route to 5-trifluoromethyl-5,6-dihydrouracils by means of palladium complex catalyzed “ureidocarbonylation” of 2-bromo-3,3,3-trifluoropropene Tetrahedron Letters. 23: 4099-4100. DOI: 10.1016/S0040-4039(00)88357-4 |
0.323 |
|
| 1982 |
Hatanaka N, Abe R, Ojima I. β‐LACTAM AS SYNTHETIC INTERMEDIATE: SYNTHESIS OF LEUCINE‐ENKEPHALIN Cheminform. 13. DOI: 10.1002/Chin.198209322 |
0.314 |
|
| 1981 |
Ojima I, Inaba S, Nagai M. Convenient Synthesis of β-Lactams by the Reaction of Ketene Silyl Acetals with Schiff Bases Promoted by Titanium(IV) Chloride Synthesis. 1981: 545-547. DOI: 10.1055/S-1981-29520 |
0.317 |
|
| 1981 |
Fuchikami T, Ojima I. Reaction of (bromodifluoromethyl)phenyldimethylsilane with organometallic reagents Journal of Organometallic Chemistry. 212: 145-153. DOI: 10.1016/S0022-328X(00)81910-5 |
0.314 |
|
| 1980 |
Ojima I, Yoda N. N-carbamoyl-4-diphenylphosphino-2-diphenylphosphinomethylpyrrolidines(CAPP). Efficient new chiral ligands for asymmetric hydrogenation Tetrahedron Letters. 21: 1051-1054. DOI: 10.1016/S0040-4039(00)78836-8 |
0.311 |
|
| 1980 |
Ojima I, Inaba S. Asymmetric synthesis of β-lactams. II. Highly effective asymmetric induction by means of “titanium template” Tetrahedron Letters. 21: 2081-2084. DOI: 10.1016/S0040-4039(00)71492-4 |
0.322 |
|
| 1980 |
Ojima I, Inaba S. Asymmetric synthesis of β-lactams. I. The reaction of dimethylketene silyl acetal with (S)-alkylidene(1-arylethyl)amines promoted by titanium tetrachloride Tetrahedron Letters. 21: 2077-2080. DOI: 10.1016/S0040-4039(00)71491-2 |
0.315 |
|
| 1980 |
Ojima I, Suzuki T. Asymmetric synthesis of dipeptides by means of homogeneous hydrogenation catalyzed by chiral rhodium complexes Tetrahedron Letters. 21: 1239-1242. DOI: 10.1016/S0040-4039(00)71381-5 |
0.3 |
|
| 1980 |
Ojima I, Kogure T. The asymmetric hydrogenation of α-keto esters catalyzed by rhodium(I) complexes with chiral diphosphine ligands. On the catalytic cycles and the mechanism of asymmetric induction Journal of Organometallic Chemistry. 195: 239-248. DOI: 10.1016/S0022-328X(00)90008-1 |
0.318 |
|
| 1980 |
Ojima I, Suga S, Abe R. A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones Tetrahedron Letters. 21: 3907-3910. DOI: 10.1016/0040-4039(80)80213-9 |
0.342 |
|
| 1979 |
OJIMA I, FUCHIKAMI T. Journal of Synthetic Organic Chemistry, Japan. 37: 739-754. DOI: 10.5059/Yukigoseikyokaishi.37.739 |
0.318 |
|
| 1979 |
Inaba S, Ojima I, Yoshida K, Nagai M. Reactions of silyl enol ethers and ketene silyl ketals with isocyanates Journal of Organometallic Chemistry. 164: 123-134. DOI: 10.1016/S0022-328X(00)86696-6 |
0.328 |
|
| 1979 |
Inaba S, Ojima I. Reaction of trimethylsilyl cyanide with isocyanates and carbodiimides Journal of Organometallic Chemistry. 169: 171-184. DOI: 10.1016/S0022-328X(00)81156-0 |
0.326 |
|
| 1978 |
OJIMA I, INABA S. Journal of Synthetic Organic Chemistry, Japan. 36: 610-615. DOI: 10.5059/Yukigoseikyokaishi.36.610 |
0.336 |
|
| 1978 |
Ojima I, Kogure T, Achiwa K. EFFECTIVE ASYMMETRIC HYDROGENATION OF ITACONIC ACID CATALYZED BY NEUTRAL AND CATIONIC RHODIUM(I) COMPLEXES WITH CHIRAL PYRROLIDINODIPHOSPHINE LIGAND Chemistry Letters. 7: 567-568. DOI: 10.1246/Cl.1978.567 |
0.303 |
|
| 1978 |
Ojima I, Kumagai M. Regioselective hydrosilylation of 1,3-dienes catalyzed by phosphine complexes of palladium and rhodium Journal of Organometallic Chemistry. 157: 359-372. DOI: 10.1016/S0022-328X(00)91720-0 |
0.336 |
|
| 1978 |
ACHIWA K, KOGURE T, OJIMA I. ChemInform Abstract: ASYMMETRIC REACTIONS CATALYZED BY CHIRAL METAL COMPLEXES. VIII. HIGHLY EFFECTIVE CATALYTIC ASYMMETRIC SYNTHESIS OF R-(-)-PANTOLACTONE Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197840196 |
0.311 |
|
| 1977 |
Ojima I, Kogure T, Achiwa K. Effective homogeneous hydrogenation of α-keto esters catalysed by neutral rhodium(I) complexes with phosphine ligands and application to the asymmetric synthesis of lactates Journal of the Chemical Society, Chemical Communications. 428-430. DOI: 10.1039/C39770000428 |
0.301 |
|
| 1977 |
Ojima I, Kogure T, Kumagai M. Reduction of carbonyl compounds via hydrosilylation. 3. Asymmetric reduction of keto esters via hydrosilylation catalyzed by a rhodium complex with chiral phosphine ligands The Journal of Organic Chemistry. 42: 1671-1679. DOI: 10.1021/Jo00430A001 |
0.322 |
|
| 1977 |
Ojima I, Kumagai M, Miyazawa Y. 3-TMS-cyclopentene-1 a new reagent for the synthesis of cyclopentene derivatives Tetrahedron Letters. 18: 1385-1388. DOI: 10.1016/S0040-4039(01)93050-3 |
0.315 |
|
| 1977 |
Inaba S, Ojima I. Novel and convenient route to substituted succinates. The dimerization of ketene silyl acetals promoted by titanium tetrachloride Tetrahedron Letters. 18: 2009-2012. DOI: 10.1016/S0040-4039(01)83666-2 |
0.324 |
|
| 1977 |
Ojima I, Inaba S, Yoshida K. New and effective route to β-lactams. The reaction of ketene silyl acetals with schiff bases promoted by titanium tetrachloride Tetrahedron Letters. 18: 3643-3646. DOI: 10.1016/S0040-4039(01)83315-3 |
0.303 |
|
| 1977 |
Ojima I. Stereochemistry of the regiospecific hydrosilylation of isoprene catalyzed by a phosphine-palladium complex Journal of Organometallic Chemistry. 134: C1-C5. DOI: 10.1016/S0022-328X(00)93621-0 |
0.329 |
|
| 1977 |
Ojima I, Inaba S. Reduction of isocyanates and carbodiimides via hydrosilylation Journal of Organometallic Chemistry. 140: 97-111. DOI: 10.1016/S0022-328X(00)84400-9 |
0.3 |
|
| 1977 |
Ojima I, Yamamoto K, Kumada M. Asymmetric Hydrosilylation by Means of Homogeneous Catalysts with Chiral Ligands Cheminform. 9: 185-228. DOI: 10.1007/978-94-010-1199-0_3 |
0.324 |
|
| 1977 |
Ojima I, Yoshida K, Inaba S. ASYMMETRIC CROSS ALDOL SYNTHESIS. ASYMMETRIC ADDITION OF SILYL ENOL ETHER AND KETENE SILYL ACETAL TO α-KETO ESTERS Chemistry Letters. 6: 429-432. DOI: 10.1002/Chin.197805092 |
0.311 |
|
| 1977 |
Ojima I, Kogure T, Achiwa K. EFFECTIVE HOMOGENEOUS HYDROGENATION OF α‐KETO ESTERS CATALYZED BY NEUTRAL RHODIUM(I) COMPLEXES WITH PHOSPHINE LIGANDS AND APPLICATION TO THE ASYMMETRIC SYNTHESIS OF LACTATES Cheminform. 8. DOI: 10.1002/Chin.197746114 |
0.304 |
|
| 1976 |
Ojima I, Miyazawa Y, Kumagai M. Asymmetric addition of allyltrimethylsilane to (–)-menthyl pyruvate and phenylglyoxylate Journal of the Chemical Society, Chemical Communications. 927-928. DOI: 10.1039/C39760000927 |
0.3 |
|
| 1975 |
OJIMA I, NIHONYANAGI M, KOGURE T, KUMAGAI M, HORIUCI S, NAKATSUGAWA K, NAGAI Y. ChemInform Abstract: REDUCTION OF CARBONYL COMPOUNDS VIA HYDROSILYLATION PART 1, HYDROSILYLATION OF CARBONYL COMPOUNDS CATALYZED BY TRIS(TRIPHENYLPHOSPHINE)CHLORORHODIUM Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197551147 |
0.32 |
|
| 1974 |
Ojima I, Nagai Y. ASYMMETRIC REDUCTION OF KETONES VIA HYDROSILYLATION CATALYZED BY A RHODIUM(I) COMPLEX WITH CHIRAL PHOSPHINE LIGANDS. II. ON THE MECHANISM OF THE INDUCTION OF ASYMMETRY Chemistry Letters. 3: 223-228. DOI: 10.1246/Cl.1974.223 |
0.31 |
|
| 1974 |
Ojima I, Inaba S, Nagai Y. Reaction of trimethylsilyl cyanide with isocyanates Journal of the Chemical Society, Chemical Communications. 826-827. DOI: 10.1039/C39740000826 |
0.317 |
|
| 1974 |
Ojima I, Kumagai M, Nagai Y. The stereochemistry of the addition of hydrosilanes to alkyl acetylenes catalyzed by tris(triphenylphosphine)-chlororhodium Journal of Organometallic Chemistry. 66: C14-C16. DOI: 10.1016/S0022-328X(00)93873-7 |
0.33 |
|
| 1973 |
Ojima I, Inaba S, Nagai Y. A novel route to formamides and their derivatives. Reduction of isocyanates via hydrosilylation catalyzed by palladium Tetrahedron Letters. 14: 4363-4366. DOI: 10.1016/S0040-4039(01)87223-3 |
0.341 |
|
| 1973 |
Ojima I, Inaba S, Nagai Y. A novel route to 2-carbamoylcycloalkanones by the addition reaction of silyl enol ethers to isocyanates Tetrahedron Letters. 14: 4271-4272. DOI: 10.1016/S0040-4039(01)87167-7 |
0.333 |
|
| 1973 |
Ojima I, Nagai Y. Reactions of triethylsilyl thiophenoxide with ketones having an electron-with-drawing group on the α-carbon Journal of Organometallic Chemistry. 57: C42-C44. DOI: 10.1016/S0022-328X(00)86579-1 |
0.327 |
|
| 1973 |
Ojima I, Akiba K, Inamoto N. Reactions of Diphenylphosphinothioyl Isothiocyanate and Related Compounds with Some Nucleophiles and Carbodiimides Bulletin of the Chemical Society of Japan. 46: 2559-2562. DOI: 10.1002/Chin.197344366 |
0.304 |
|
| 1972 |
Kondo K, Ojima I. Reactions of carbenes bearing sulphide linkages at the δ-position Journal of the Chemical Society, Chemical Communications. 860-861. DOI: 10.1039/C39720000860 |
0.338 |
|
| 1972 |
Kondo K, Negishi A, Ojima I. Acid-catalyzed ring opening reactions of episulfoxides Journal of the American Chemical Society. 94: 5786-5793. DOI: 10.1021/Ja00771A042 |
0.309 |
|
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