| Year |
Citation |
Score |
| 2022 |
Wang H, Taouil A, Awwa M, Clement T, Zhu C, Kim J, Rendina D, Jayanetti K, Maharaj A, Wang L, Bogdan D, Pepe A, Kaczocha M, Ojima I. SAR study on Novel truxillic acid monoester-Based inhibitors of fatty acid binding proteins as Next-Generation antinociceptive agents. Bioorganic Chemistry. 129: 106184. PMID 36244323 DOI: 10.1016/j.bioorg.2022.106184 |
0.506 |
|
| 2020 |
Rong D, Wang C, Zhang X, Wei Y, Zhang M, Liu D, Farhan H, Momen Ali SA, Liu Y, Taouil A, Guo W, Wang Y, Ojima I, Yang S, Wang H. A novel taxane, difluorovinyl-ortataxel, effectively overcomes paclitaxel-resistance in breast cancer cells. Cancer Letters. PMID 32730778 DOI: 10.1016/J.Canlet.2020.06.025 |
0.345 |
|
| 2020 |
Lazzarini C, Haranahalli K, McCarthy JB, Mallamo J, Ojima I, Del Poeta M. Preclinical evaluation of acylhydrazone SB-AF-1002 as a novel broad-spectrum antifungal agent. Antimicrobial Agents and Chemotherapy. PMID 32601165 DOI: 10.1128/Aac.00946-20 |
0.324 |
|
| 2019 |
Wang C, Wang X, Sun Y, Taouil AK, Yan S, Botchkina GI, Ojima I. Design, synthesis and SAR study of 3rd-generation taxoids bearing 3-CH, 3-CFO and 3-CHFO groups at the C2-benzoate position. Bioorganic Chemistry. 95: 103523. PMID 31911305 DOI: 10.1016/J.Bioorg.2019.103523 |
0.395 |
|
| 2019 |
Carbonetti G, Converso C, Clement T, Wang C, Trotman L, Ojima I, Kaczocha M. Docetaxel/cabazitaxel and fatty acid binding protein 5 inhibitors produce synergistic inhibition of prostate cancer growth. The Prostate. PMID 31661167 DOI: 10.1002/Pros.23921 |
0.322 |
|
| 2019 |
Haranahalli K, Honda T, Ojima I. Recent progress in the strategic incorporation of fluorine into medicinally active compounds. Journal of Fluorine Chemistry. 217: 29-40. PMID 31537946 DOI: 10.1016/J.Jfluchem.2018.11.002 |
0.367 |
|
| 2019 |
Haranahalli K, Lazzarini C, Sun Y, Zambito J, Pathiranage S, McCarthy JB, Mallamo JP, Del Poeta M, Ojima I. SAR Studies on Aromatic Acylhydrazone-Based Inhibitors of Fungal Sphingolipid Synthesis as Next-Generation Antifungal Agents. Journal of Medicinal Chemistry. PMID 31369263 DOI: 10.1021/Acs.Jmedchem.9B01004 |
0.356 |
|
| 2018 |
Teng YG, Chien CW, Chiou WH, Honda T, Ojima I. Construction of Fused Tropone Systems Through Intramolecular Rh(I)-Catalyzed Carbonylative [2+2+2+1] Cycloadditon of Triynes. Frontiers in Chemistry. 6: 401. PMID 30250840 DOI: 10.3389/Fchem.2018.00401 |
0.71 |
|
| 2018 |
Chien CW, Teng YG, Honda T, Ojima I. Synthesis of Colchicinoids and Allocolchicinoids through Rh(I)-catalyzed [2+2+2+1] and [2+2+2] Cycloadditions of o-Phenylenetriynes with and without CO. The Journal of Organic Chemistry. PMID 30129760 DOI: 10.1021/Acs.Joc.8B01608 |
0.592 |
|
| 2018 |
Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, ... ... Ojima I, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. European Journal of Medicinal Chemistry. 154: 233-252. PMID 29803996 DOI: 10.1016/J.Ejmech.2018.04.050 |
0.321 |
|
| 2018 |
Jelínek M, Balušíková K, Daniel P, Němcová-Fürstová V, Kirubakaran P, Jaček M, Wei L, Wang X, Vondrášek J, Ojima I, Kovář J. Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel. Toxicology and Applied Pharmacology. PMID 29625142 DOI: 10.1016/J.Taap.2018.04.002 |
0.311 |
|
| 2018 |
Yang CH, Wang C, Ojima I, Horwitz SB. Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of β-Tubulin and the Multidrug Resistance Associated P-Glycoprotein. Journal of Natural Products. PMID 29517223 DOI: 10.1021/Acs.Jnatprod.7B01047 |
0.348 |
|
| 2018 |
Lazzarini C, Haranahalli K, Rieger R, Ananthula HK, Desai PB, Ashbaugh A, Linke MJ, Cushion MT, Ruzsicska B, Haley J, Ojima I, Del Poeta M. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrobial Agents and Chemotherapy. PMID 29507066 DOI: 10.1128/Aac.00156-18 |
0.359 |
|
| 2018 |
Ojima I, Wang X, Jing Y, Wang C. Quest for Efficacious Next-Generation Taxoid Anticancer Agents and Their Tumor-Targeted Delivery. Journal of Natural Products. PMID 29468872 DOI: 10.1021/Acs.Jnatprod.7B01012 |
0.418 |
|
| 2018 |
Seitz JD, Wang T, Vineberg JG, Honda T, Ojima I. Synthesis of a Next-Generation Taxoid by Rapid Methylation Amenable for 11C-Labeling. The Journal of Organic Chemistry. PMID 29441783 DOI: 10.1021/Acs.Joc.7B03284 |
0.804 |
|
| 2017 |
Wang T, Vineberg JG, Honda T, Ojima I. Design and synthesis of tumor-targeting theranostic drug conjugates for SPECT and PET imaging studies. Bioorganic Chemistry. 76: 458-467. PMID 29287255 DOI: 10.1016/J.Bioorg.2017.12.018 |
0.79 |
|
| 2017 |
Ojima I. Strategic Incorporation of Fluorine into Taxoid Anticancer Agents for Medicinal Chemistry and Chemical Biology Studies. Journal of Fluorine Chemistry. 198: 10-23. PMID 28824201 DOI: 10.1016/J.Jfluchem.2016.12.016 |
0.35 |
|
| 2017 |
Ahmad G, El Sadda R, Botchkina G, Ojima I, Egan J, Amiji M. Nanoemulsion Formulation of a Novel Taxoid DHA-SBT-1214 Inhibits Prostate Cancer Stem Cell-Induced Tumor Growth. Cancer Letters. PMID 28803993 DOI: 10.1016/J.Canlet.2017.08.004 |
0.329 |
|
| 2017 |
Ojima I, Awasthi D, Wei L, Haranahalli K. Strategic incorporation of fluorine in the drug discovery of new-generation antitubercular agents targeting bacterial cell division protein FtsZ. Journal of Fluorine Chemistry. 196: 44-56. PMID 28555087 DOI: 10.1016/J.Jfluchem.2016.07.020 |
0.388 |
|
| 2017 |
Jelinek M, Kabelova A, Sramek J, Seitz J, Ojima I, Kovar J. Differing Mechanisms of Death Induction by Fluorinated Taxane SB-T-12854 in Breast Cancer Cells. Anticancer Research. 37: 1581-1590. PMID 28373418 DOI: 10.21873/Anticanres.11488 |
0.547 |
|
| 2017 |
Zheng X, Wang C, Xing Y, Chen S, Meng T, You H, Ojima I, Dong Y. SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells. International Journal of Oncology. PMID 28197640 DOI: 10.3892/Ijo.2017.3871 |
0.322 |
|
| 2016 |
Islam MM, Hameed HM, Mugweru J, Chhotaray C, Wang C, Tan Y, Liu J, Li X, Tan S, Ojima I, Yew WW, Nuermberger E, Lamichhane G, Zhang T. Drug resistance mechanisms and novel drug targets for tuberculosis therapy. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 28117224 DOI: 10.1016/J.Jgg.2016.10.002 |
0.318 |
|
| 2016 |
Haranahalli K, Tong S, Ojima I. Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ. Bioorganic & Medicinal Chemistry. PMID 27189886 DOI: 10.1016/J.Bmc.2016.05.003 |
0.347 |
|
| 2016 |
Yang CH, Wang C, Ojima I, Horwitz SB. Abstract 1229: The next-generation taxanes, SB-T-1214 and SB-CST-10202, exhibit distinct inhibitory effects on photolabeling of β-tubulin from different eukaryotic sources Cancer Research. 76: 1229-1229. DOI: 10.1158/1538-7445.Am2016-1229 |
0.341 |
|
| 2016 |
Afrimzon E, Botchkina G, Zurgil N, Shafran Y, Sobolev M, Moshkov S, Ravid-Hermesh O, Ojima I, Deutsch M. Hydrogel microstructure live-cell array for multiplexed analyses of cancer stem cells, tumor heterogeneity and differential drug response at single-element resolution Lab On a Chip - Miniaturisation For Chemistry and Biology. 16: 1047-1062. DOI: 10.1039/C6Lc00014B |
0.344 |
|
| 2015 |
Ojima I, Lichtenthal B, Lee S, Wang C, Wang X. Taxane anticancer agents: a patent perspective. Expert Opinion On Therapeutic Patents. 1-20. PMID 26651178 DOI: 10.1517/13543776.2016.1111872 |
0.319 |
|
| 2015 |
Teng YH, Berger WT, Nesbitt NM, Kumar K, Balius TE, Rizzo RC, Tonge PJ, Ojima I, Swaminathan S. Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A. Bioorganic & Medicinal Chemistry. 23: 5489-95. PMID 26275678 DOI: 10.1016/J.Bmc.2015.07.040 |
0.723 |
|
| 2015 |
Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, et al. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. Mbio. 6. PMID 26106079 DOI: 10.1128/Mbio.00647-15 |
0.371 |
|
| 2015 |
Li W, Zheng S, Higgins M, Morra RP, Mendis AT, Chien CW, Ojima I, Mierke DF, Dinkova-Kostova AT, Honda T. New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase. Journal of Medicinal Chemistry. 58: 4738-48. PMID 25965897 DOI: 10.1021/Acs.Jmedchem.5B00393 |
0.605 |
|
| 2015 |
Seitz JD, Vineberg JG, Herlihy E, Park B, Melief E, Ojima I. Design, synthesis and biological evaluation of a highly-potent and cancer cell selective folate-taxoid conjugate. Bioorganic & Medicinal Chemistry. 23: 2187-94. PMID 25819334 DOI: 10.1016/J.Bmc.2015.02.057 |
0.812 |
|
| 2015 |
He Z, Schulz A, Wan X, Seitz J, Bludau H, Alakhova DY, Darr DB, Perou CM, Jordan R, Ojima I, Kabanov AV, Luxenhofer R. Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: preparation, in vitro and in vivo evaluation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 208: 67-75. PMID 25725361 DOI: 10.1016/J.Jconrel.2015.02.024 |
0.603 |
|
| 2015 |
Seitz JD, Vineberg JG, Wei L, Khan JF, Lichtenthal B, Lin CF, Ojima I. Design, Synthesis and Application of Fluorine-Labeled Taxoids as (19)F NMR Probes for the Metabolic Stability Assessment of Tumor-Targeted Drug Delivery Systems. Journal of Fluorine Chemistry. 171: 148-161. PMID 25722499 DOI: 10.1016/J.Jfluchem.2014.08.006 |
0.787 |
|
| 2015 |
Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG. Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The Journal of Biological Chemistry. 290: 8711-21. PMID 25666611 DOI: 10.1074/Jbc.M114.618447 |
0.637 |
|
| 2015 |
Vineberg JG, Wang T, Zuniga ES, Ojima I. Design, synthesis, and biological evaluation of theranostic vitamin-linker-taxoid conjugates. Journal of Medicinal Chemistry. 58: 2406-16. PMID 25654690 DOI: 10.1021/Jm5019115 |
0.794 |
|
| 2015 |
Zang Y, Ojima I. Pd-catalyzed asymmetric allylic amination with BOP ligands and its applications to the synthesis of fused polycyclic alkaloids Tetrahedron Letters. 56: 3288-3292. DOI: 10.1016/J.Tetlet.2015.01.047 |
0.573 |
|
| 2014 |
Matesanz R, Trigili C, RodrÃguez-Salarichs J, Zanardi I, Pera B, Nogales A, Fang WS, JÃmenez-Barbero J, Canales A, Barasoain I, Ojima I, DÃaz JF. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances. Bioorganic & Medicinal Chemistry. 22: 5078-90. PMID 25047938 DOI: 10.1016/J.Bmc.2014.05.048 |
0.305 |
|
| 2014 |
Rowehl RA, Burke S, Bialkowska AB, Pettet DW, Rowehl L, Li E, Antoniou E, Zhang Y, Bergamaschi R, Shroyer KR, Ojima I, Botchkina GI. Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. Plos One. 9: e99091. PMID 24921652 DOI: 10.1371/Journal.Pone.0099091 |
0.322 |
|
| 2014 |
Vineberg JG, Zuniga ES, Kamath A, Chen YJ, Seitz JD, Ojima I. Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy. Journal of Medicinal Chemistry. 57: 5777-91. PMID 24901491 DOI: 10.1021/Jm500631U |
0.804 |
|
| 2014 |
Knudson SE, Kumar K, Awasthi D, Ojima I, Slayden RA. In vitro-in vivo activity relationship of substituted benzimidazole cell division inhibitors with activity against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 94: 271-6. PMID 24746463 DOI: 10.1016/J.Tube.2014.03.007 |
0.312 |
|
| 2014 |
Park B, Awasthi D, Chowdhury SR, Melief EH, Kumar K, Knudson SE, Slayden RA, Ojima I. Design, synthesis and evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents. Bioorganic & Medicinal Chemistry. 22: 2602-12. PMID 24726304 DOI: 10.1016/J.Bmc.2014.03.035 |
0.646 |
|
| 2014 |
Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I. Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. Plos One. 9: e94200. PMID 24705380 DOI: 10.1371/Journal.Pone.0094200 |
0.707 |
|
| 2014 |
Ojima I, Kumar K, Awasthi D, Vineberg JG. Drug discovery targeting cell division proteins, microtubules and FtsZ. Bioorganic & Medicinal Chemistry. 22: 5060-77. PMID 24680057 DOI: 10.1016/J.Bmc.2014.02.036 |
0.798 |
|
| 2014 |
Moriwaki H, Resch D, Li H, Ojima I, Takeda R, Aceña JL, Soloshonok V. Inexpensive chemical method for preparation of enantiomerically pure phenylalanine. Amino Acids. 46: 945-52. PMID 24385244 DOI: 10.1007/S00726-013-1656-0 |
0.33 |
|
| 2014 |
Lin CF, Chien CW, Ojima I. Enantioselective Pd-catalyzed tandem allylic alkylation reaction using monodentate phosphoramidite ligands for the formal total synthesis of huperzine A Organic Chemistry Frontiers. 1: 1062-1066. DOI: 10.1039/C4Qo00180J |
0.727 |
|
| 2014 |
Ojima I, Kamath A, Seitz JD. Taxol, Taxoids, and Related Taxanes Natural Products in Medicinal Chemistry. 127-180. DOI: 10.1002/9783527676545.ch04 |
0.438 |
|
| 2013 |
Awasthi D, Kumar K, Knudson SE, Slayden RA, Ojima I. SAR studies on trisubstituted benzimidazoles as inhibitors of Mtb FtsZ for the development of novel antitubercular agents. Journal of Medicinal Chemistry. 56: 9756-70. PMID 24266862 DOI: 10.1021/Jm401468W |
0.341 |
|
| 2013 |
Botchkina GI, Zuniga ES, Rowehl RH, Park R, Bhalla R, Bialkowska AB, Johnson F, Golub LM, Zhang Y, Ojima I, Shroyer KR. Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24. Plos One. 8: e69884. PMID 24086245 DOI: 10.1371/Journal.Pone.0069884 |
0.781 |
|
| 2013 |
Seitz J, Vineberg JG, Zuniga ES, Ojima I. Fluorine-Containing Taxoid Anticancer Agents and Their Tumor-Targeted Drug Delivery. Journal of Fluorine Chemistry. 152: 157-165. PMID 23935213 DOI: 10.1016/J.Jfluchem.2013.05.013 |
0.798 |
|
| 2013 |
Kumar K, Awasthi D, Lee SY, Cummings JE, Knudson SE, Slayden RA, Ojima I. Benzimidazole-based antibacterial agents against Francisella tularensis. Bioorganic & Medicinal Chemistry. 21: 3318-26. PMID 23623254 DOI: 10.1016/J.Bmc.2013.02.059 |
0.714 |
|
| 2013 |
Zang Y, Ojima I. Pd-catalyzed asymmetric allylic etherification using chiral biphenol-based diphosphinite ligands and its application for the formal total synthesis of (-)-galanthamine. The Journal of Organic Chemistry. 78: 4013-8. PMID 23472673 DOI: 10.1021/Jo400355J |
0.57 |
|
| 2013 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. High throughput fluorescence displacement assay with NBD-stearate. Plos One. DOI: 10.1371/Journal.Pone.0050968.G008 |
0.6 |
|
| 2013 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Scheme demonstrating anandamide inactivation and FABP drug target. Plos One. DOI: 10.1371/Journal.Pone.0050968.G001 |
0.641 |
|
| 2013 |
Zheng S, Chowdhury A, Ojima I, Honda T. Microwave-assisted Diels-Alder reactions between Danishefsky's diene and derivatives of ethyl α-(hydroxymethyl)acrylate. Synthetic approach toward a biotinylated anti-inflammatory monocyclic cyanoenone Tetrahedron. 69: 2052-2055. DOI: 10.1016/J.Tet.2012.12.079 |
0.309 |
|
| 2013 |
Ojima I, Athan A, Commandeur C, Chiou WH. Amidocarbonylation, Cyclohydrocarbonylation, and Related Reactions Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. DOI: 10.1016/B978-0-12-409547-2.03980-9 |
0.784 |
|
| 2012 |
Kamath A, Ojima I. Advances in the chemistry of β-lactam and its medicinal applications. Tetrahedron. 68: 10640-10664. PMID 23264702 DOI: 10.1016/J.Tet.2012.07.090 |
0.335 |
|
| 2012 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. Plos One. 7: e50968. PMID 23236415 DOI: 10.1371/Journal.Pone.0050968 |
0.662 |
|
| 2012 |
Kuznetsova L, Sun L, Chen J, Zhao X, Seitz J, Das M, Li Y, Veith JM, Pera P, Bernacki RJ, Xia S, Horwitz SB, Ojima I. Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids. Journal of Fluorine Chemistry. 143: 177-188. PMID 23139432 DOI: 10.1016/J.Jfluchem.2012.07.007 |
0.798 |
|
| 2012 |
Ehrlichová M, Ojima I, Chen J, Václavíková R, N?mcová-Fürstová V, Vobo?ilová J, Simek P, Horský S, Sou?ek P, Ková? J, Brabec M, Gut I. Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 1035-48. PMID 22855252 DOI: 10.1007/S00210-012-0785-4 |
0.325 |
|
| 2012 |
Zheng S, Santosh Laxmi YR, David E, Dinkova-Kostova AT, Shiavoni KH, Ren Y, Zheng Y, Trevino I, Bumeister R, Ojima I, Wigley WC, Bliska JB, Mierke DF, Honda T. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents. Journal of Medicinal Chemistry. 55: 4837-46. PMID 22533790 DOI: 10.1021/Jm3003922 |
0.308 |
|
| 2012 |
Ojima I, Zuniga ES, Berger WT, Seitz JD. Tumor-targeting drug delivery of new-generation taxoids. Future Medicinal Chemistry. 4: 33-50. PMID 22168163 DOI: 10.4155/Fmc.11.167 |
0.799 |
|
| 2012 |
Ojima I, Delaloge F. Syntheses of Norstatine, Its Analogs, and Dipeptide Isosteres by Means of β-Lactam Synthon Method. Methods in Molecular Medicine. 23: 137-60. PMID 21380896 DOI: 10.1385/0-89603-517-4:137 |
0.301 |
|
| 2012 |
Ehrlichova M, Vaclavikova R, Brynychova V, Nemcova V, Pecha V, Mrhalova M, Rob R, Ojima I, Gut I, Soucek P. 1045 Efficiency and Transport of Taxanes in Human Cancer Cell Lines and Solid Tumors European Journal of Cancer. 48: S252. DOI: 10.1016/S0959-8049(12)71656-8 |
0.308 |
|
| 2011 |
Lin CF, Ojima I. Formal enantioselective total synthesis of schulzeines A-C via Pd-catalyzed intramolecular asymmetric allylic amination. The Journal of Organic Chemistry. 76: 6240-9. PMID 21671593 DOI: 10.1021/Jo2009615 |
0.629 |
|
| 2011 |
Banerjee PS, Zuniga ES, Ojima I, Carrico IS. Targeted and armed oncolytic adenovirus via chemoselective modification. Bioorganic & Medicinal Chemistry Letters. 21: 4985-8. PMID 21669527 DOI: 10.1016/J.Bmcl.2011.05.039 |
0.765 |
|
| 2011 |
Awasthi D, Kumar K, Ojima I. Therapeutic potential of FtsZ inhibition: a patent perspective. Expert Opinion On Therapeutic Patents. 21: 657-79. PMID 21413908 DOI: 10.1517/13543776.2011.568483 |
0.335 |
|
| 2011 |
Shi C, Chien CW, Ojima I. Synthesis of chiral biphenol-based diphosphonite ligands and their application in palladium-catalyzed intermolecular asymmetric allylic amination reactions. Chemistry, An Asian Journal. 6: 674-80. PMID 21254441 DOI: 10.1002/Asia.201000697 |
0.61 |
|
| 2011 |
Kumar K, Awasthi D, Lee SY, Zanardi I, Ruzsicska B, Knudson S, Tonge PJ, Slayden RA, Ojima I. Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents. Journal of Medicinal Chemistry. 54: 374-81. PMID 21126020 DOI: 10.1021/Jm1012006 |
0.746 |
|
| 2011 |
Vobořilová J, Němcová-Fürstová V, Neubauerová J, Ojima I, Zanardi I, Gut I, Kovář J. Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells Investigational New Drugs. 29: 411-423. PMID 20013348 DOI: 10.1007/S10637-009-9368-8 |
0.314 |
|
| 2011 |
Ojima I. Tumor-targeting drug delivery of chemotherapeutic agents Pure and Applied Chemistry. 83: 1685-1698. DOI: 10.1351/Pac-Con-11-02-10 |
0.377 |
|
| 2011 |
Chien CW, Shi C, Lin CF, Ojima I. Enantioselective synthesis of 1-vinyltetrahydroisoquinolines via Pd-catalyzed intramolecular asymmetric allylic amination reactions Tetrahedron. 67: 6513-6523. DOI: 10.1016/J.Tet.2011.05.125 |
0.719 |
|
| 2011 |
Seitz J, Ojima I. Drug Conjugates with Polyunsaturated Fatty Acids Drug Delivery in Oncology: From Basic Research to Cancer Therapy. 3: 1323-1357. DOI: 10.1002/9783527634057.ch41 |
0.499 |
|
| 2010 |
Kumar K, Awasthi D, Berger WT, Tonge PJ, Slayden RA, Ojima I. Discovery of anti-TB agents that target the cell-division protein FtsZ. Future Medicinal Chemistry. 2: 1305-23. PMID 21339840 DOI: 10.4155/Fmc.10.220 |
0.668 |
|
| 2010 |
Sun L, Veith JM, Pera P, Bernacki RJ, Ojima I. Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel. Bioorganic & Medicinal Chemistry. 18: 7101-12. PMID 20800500 DOI: 10.1016/J.Bmc.2010.07.069 |
0.366 |
|
| 2010 |
Botchkina GI, Zuniga ES, Das M, Wang Y, Wang H, Zhu S, Savitt AG, Rowehl RA, Leyfman Y, Ju J, Shroyer K, Ojima I. New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. Molecular Cancer. 9: 192. PMID 20630067 DOI: 10.1186/1476-4598-9-192 |
0.789 |
|
| 2010 |
Chen S, Zhao X, Chen J, Chen J, Kuznetsova L, Wong SS, Ojima I. Mechanism-based tumor-targeting drug delivery system. Validation of efficient vitamin receptor-mediated endocytosis and drug release. Bioconjugate Chemistry. 21: 979-87. PMID 20429547 DOI: 10.1021/Bc9005656 |
0.706 |
|
| 2010 |
Botchkina GI, Ju J, Savitt AG, Rowehl RA, Zuniga E, Das M, Wang H, Zhu S, Ojima I. Abstract 3331: New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in colon and prostate CSCs Cancer Research. 70: 3331-3331. DOI: 10.1158/1538-7445.Am10-3331 |
0.784 |
|
| 2010 |
Ji JX, Chan ASC, Helmchen G, Kazmaier U, Förster S, Ojima I, Kaloko JJ, Chaterpaul SJ, Teng YHG, Lin CF, Mikami K, Aikawa K, Hoveyda AH, Malcolmson SJ, Meek SJ, et al. Asymmetric Carbon-Carbon Bond-Forming Reactions Catalytic Asymmetric Synthesis: Third Edition. 437-770. DOI: 10.1002/9780470584248.ch8 |
0.75 |
|
| 2009 |
DAS M, Zuniga E, Ojima I. Novel Taxoid-Based Tumor-Targeting Drug Conjugates. Chimica Oggi. 27: 54-56. PMID 21822353 |
0.805 |
|
| 2009 |
Ojima I. Medicinal chemistry at a crossroads: challenges and new possibilities. Future Medicinal Chemistry. 1: 401-3. PMID 21426118 DOI: 10.4155/Fmc.09.37 |
0.314 |
|
| 2009 |
Kaloko JJ, Teng YH, Ojima I. One-step formation of fused tetracyclic skeletons from cyclohexene-diynes and carbon monoxide through Rh(I)-catalyzed [2 + 2 + 2 + 1] cycloaddition reaction. Chemical Communications (Cambridge, England). 4569-71. PMID 19617986 DOI: 10.1039/B909781C |
0.787 |
|
| 2009 |
Chiou WH, Lin GH, Hsu CC, Chaterpaul SJ, Ojima I. Efficient syntheses of crispine A and harmicine by RH-catalyzed cyclohydrocarbonylation. Organic Letters. 11: 2659-62. PMID 19456145 DOI: 10.1021/Ol900702T |
0.789 |
|
| 2009 |
Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I. Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin. Bioorganic & Medicinal Chemistry Letters. 19: 3300-4. PMID 19423340 DOI: 10.1016/J.Bmcl.2009.04.070 |
0.702 |
|
| 2009 |
Sun L, Simmerling C, Ojima I. Recent advances in the study of the bioactive conformation of taxol. Chemmedchem. 4: 719-31. PMID 19360801 DOI: 10.1002/Cmdc.200900044 |
0.331 |
|
| 2009 |
Ojima I, Das M. Recent advances in the chemistry and biology of new generation taxoids. Journal of Natural Products. 72: 554-65. PMID 19239240 DOI: 10.1021/Np8006556 |
0.634 |
|
| 2009 |
Gut I, Vaclavikova R, Ehrlichova M, Ojima I, Otova B, Hrdy J, Kovar J, Voborilova J, Nemcova V, Zanardi I. Abstract B9: Role of disposition, transport, in vitro efficiency and expression of relevant genes in the effects of novel taxanes on subcutaneous lymphoma in Sprague‐Dawley/Cub rats Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B9 |
0.358 |
|
| 2009 |
Gut I, Ehrlichova M, Vaclavikova R, Ojima I, Simek P. Abstract A147: Novel fluorinated taxane SB‐T‐12854 active in drug‐resistant and sensitive cell lines: Human, pig, rat metabolism, cell transport, and effects on cell cycle Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A147 |
0.305 |
|
| 2009 |
Pepe A, Sun L, Zanardi I, Wu X, Ferlini C, Fontana G, Bombardelli E, Ojima I. ChemInform Abstract: Novel C-Seco-Taxoids Possessing High Potency Against Paclitaxel-Resistant Cancer Cell Lines Overexpressing Class III β-Tubulin. Cheminform. 40. DOI: 10.1002/chin.200944181 |
0.67 |
|
| 2009 |
Pepe A, Kuznetsova L, Sun L, Ojima I. Fluoro-Taxoid Anticancer Agents Fluorine in Medicinal Chemistry and Chemical Biology. 117-139. DOI: 10.1002/9781444312096.ch5 |
0.633 |
|
| 2009 |
Ojima I, Li Z, Zhu J. Recent Advances in the Hydrosilylation and Related Reactions Patai's Chemistry of Functional Groups. 1687-1792. DOI: 10.1002/9780470682531.Pat0191 |
0.331 |
|
| 2009 |
Ojima I, Das M, Zuniga E. Novel taxoid-based tumour-targeting drug conjugates Chimica Oggi. 27: 54-56. |
0.788 |
|
| 2008 |
Chiou WH, Schoenfelder A, Mann A, Ojima I. Application of Rhodium-Catalyzed Cyclohydrocarbonylation to the Syntheses of Enantiopure Homokainoids. Pure and Applied Chemistry. Chimie Pure Et Appliquee. 80: 1019-1024. PMID 19693284 DOI: 10.1351/Pac200880051019 |
0.61 |
|
| 2008 |
Chen J, Chen S, Zhao X, Kuznetsova LV, Wong SS, Ojima I. Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery. Journal of the American Chemical Society. 130: 16778-85. PMID 19554734 DOI: 10.1021/Ja805570F |
0.714 |
|
| 2008 |
Kuznetsova LV, Pepe A, Ungureanu IM, Pera P, Bernacki RJ, Ojima I. Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids. Journal of Fluorine Chemistry. 129: 817-828. PMID 19448839 DOI: 10.1016/J.Jfluchem.2008.05.013 |
0.708 |
|
| 2008 |
Sun L, Geng X, Geney R, Li Y, Simmerling C, Li Z, Lauher JW, Xia S, Horwitz SB, Veith JM, Pera P, Bernacki RJ, Ojima I. Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids. The Journal of Organic Chemistry. 73: 9584-93. PMID 18975909 DOI: 10.1021/Jo801713Q |
0.805 |
|
| 2008 |
Respicio L, Nair PA, Huang Q, Anil B, Tracz S, Truglio JJ, Kisker C, Raleigh DP, Ojima I, Knudson DL, Tonge PJ, Slayden RA. Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery. Tuberculosis (Edinburgh, Scotland). 88: 420-9. PMID 18479968 DOI: 10.1016/J.Tube.2008.03.001 |
0.327 |
|
| 2008 |
Ojima I, Chen J, Sun L, Borella CP, Wang T, Miller ML, Lin S, Geng X, Kuznetsova L, Qu C, Gallager D, Zhao X, Zanardi I, Xia S, Horwitz SB, et al. Design, synthesis, and biological evaluation of new-generation taxoids. Journal of Medicinal Chemistry. 51: 3203-21. PMID 18465846 DOI: 10.1021/Jm800086E |
0.798 |
|
| 2008 |
Ojima I. Modern natural products chemistry and drug discovery. Journal of Medicinal Chemistry. 51: 2587-8. PMID 18393400 DOI: 10.1021/Jm701291U |
0.303 |
|
| 2008 |
Xu H, Sullivan TJ, Sekiguchi J, Kirikae T, Ojima I, Stratton CF, Mao W, Rock FL, Alley MR, Johnson F, Walker SG, Tonge PJ. Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus. Biochemistry. 47: 4228-36. PMID 18335995 DOI: 10.1021/Bi800023A |
0.317 |
|
| 2008 |
Ojima I. Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads. Accounts of Chemical Research. 41: 108-19. PMID 17663526 DOI: 10.1021/Ar700093F |
0.387 |
|
| 2007 |
Chiou WH, Schoenfelder A, Sun L, Mann A, Ojima I. Rhodium-catalyzed cyclohydrocarbonylation approach to the syntheses of enantiopure homokainoids. The Journal of Organic Chemistry. 72: 9418-25. PMID 17999516 DOI: 10.1021/Jo070942N |
0.619 |
|
| 2007 |
Huang Q, Tonge PJ, Slayden RA, Kirikae T, Ojima I. FtsZ: a novel target for tuberculosis drug discovery. Current Topics in Medicinal Chemistry. 7: 527-43. PMID 17346197 DOI: 10.2174/156802607780059790 |
0.363 |
|
| 2007 |
Chiou WH, Mizutani N, Ojima I. Highly efficient synthesis of azabicyclo[x.y.0]alkane amino acids and congeners by means of Rh-catalyzed cyclohydrocarbonylation. The Journal of Organic Chemistry. 72: 1871-82. PMID 17346029 DOI: 10.1021/Jo061692Y |
0.628 |
|
| 2007 |
Shi C, Ojima I. Asymmetric synthesis of 1-vinyltetrahydroisoquinoline through Pd-catalyzed intramolecular allylic amination Tetrahedron. 63: 8563-8570. DOI: 10.1016/J.Tet.2007.04.097 |
0.326 |
|
| 2007 |
Ojima I, Kuznetsova LV, Sun L. Organofluorine chemistry at the biomedical interface: A case study on fluoro-taxoid anticancer agents Acs Symposium Series. 949: 288-304. |
0.475 |
|
| 2006 |
Gut I, Ojima I, Vaclavikova R, Simek P, Horsky S, Linhart I, Soucek P, Kondrova E, Kuznetsova LV, Chen J. Metabolism of new-generation taxanes in human, pig, minipig and rat liver microsomes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 36: 772-92. PMID 16971343 DOI: 10.1080/00498250600829220 |
0.527 |
|
| 2006 |
Chapsal BD, Ojima I. Total synthesis of enantiopure (+)-gamma-lycorane using highly efficient Pd-catalyzed asymmetric allylic alkylation. Organic Letters. 8: 1395-8. PMID 16562900 DOI: 10.1021/Ol060181V |
0.796 |
|
| 2006 |
Huang Q, Kirikae F, Kirikae T, Pepe A, Amin A, Respicio L, Slayden RA, Tonge PJ, Ojima I. Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents. Journal of Medicinal Chemistry. 49: 463-6. PMID 16420032 DOI: 10.1021/Jm050920Y |
0.595 |
|
| 2006 |
Kuznetsova L, Chen J, Sun L, Wu X, Pepe A, Veith JM, Pera P, Bernacki RJ, Ojima I. Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents. Bioorganic & Medicinal Chemistry Letters. 16: 974-7. PMID 16298526 DOI: 10.1016/J.Bmcl.2005.10.089 |
0.772 |
|
| 2006 |
Ojima I, Chapsal B. Total Synthesis of (+)-γ-Lycorane Synfacts. 2006: 0864-0864. DOI: 10.1055/s-2006-942051 |
0.768 |
|
| 2006 |
Chapsal BD, Hua Z, Ojima I. Catalytic asymmetric transformations with fine-tunable biphenol-based monodentate ligands Tetrahedron Asymmetry. 17: 642-657. DOI: 10.1016/J.Tetasy.2005.12.035 |
0.779 |
|
| 2005 |
Geney R, Chen J, Ojima I. Recent advances in the new generation taxane anticancer agents. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 1: 125-39. PMID 16787308 DOI: 10.2174/1573406053175292 |
0.811 |
|
| 2005 |
Bennacer B, Fujiwara M, Lee SY, Ojima I. Silicon-initiated carbonylative carbotricyclization and [2+2+2+1] cycloaddition of enediynes catalyzed by rhodium complexes. Journal of the American Chemical Society. 127: 17756-67. PMID 16351104 DOI: 10.1021/Ja054221M |
0.744 |
|
| 2005 |
Chen J, Jaracz S, Zhao X, Chen S, Ojima I. Antibody-cytotoxic agent conjugates for cancer therapy. Expert Opinion On Drug Delivery. 2: 873-90. PMID 16296784 DOI: 10.1517/17425247.2.5.873 |
0.566 |
|
| 2005 |
Ehrlichova M, Vaclavikova R, Ojima I, Pepe A, Kuznetsova LV, Chen J, Truksa J, Kovar J, Gut I. Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 372: 95-105. PMID 16059735 DOI: 10.1007/S00210-005-1080-4 |
0.691 |
|
| 2005 |
Jaracz S, Chen J, Kuznetsova LV, Ojima I. Recent advances in tumor-targeting anticancer drug conjugates. Bioorganic & Medicinal Chemistry. 13: 5043-54. PMID 15955702 DOI: 10.1016/J.Bmc.2005.04.084 |
0.616 |
|
| 2005 |
Geney R, Sun L, Pera P, Bernacki RJ, Xia S, Horwitz SB, Simmerling CL, Ojima I. Use of the tubulin bound paclitaxel conformation for structure-based rational drug design. Chemistry & Biology. 12: 339-48. PMID 15797218 DOI: 10.1016/J.Chembiol.2005.01.004 |
0.8 |
|
| 2005 |
Ojima I, Borella CP, Wu X, Bounaud PY, Oderda CF, Sturm M, Miller ML, Chakravarty S, Chen J, Huang Q, Pera P, Brooks TA, Baer MR, Bernacki RJ. Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents. Journal of Medicinal Chemistry. 48: 2218-28. PMID 15771464 DOI: 10.1021/Jm049483Y |
0.786 |
|
| 2005 |
Chiou WH, Lee SY, Ojima I. Recent advances in cyclohydrocarbonylation reactions Canadian Journal of Chemistry. 83: 681-692. DOI: 10.1139/V05-035 |
0.789 |
|
| 2004 |
Bennacer B, Fujiwara M, Ojima I. Novel [2 + 2 + 2 + 1] cycloaddition of enediynes catalyzed by rhodium complexes. Organic Letters. 6: 3589-91. PMID 15387555 DOI: 10.1021/Ol048500A |
0.347 |
|
| 2004 |
Choi H, Hua Z, Ojima I. Highly enantioselective copper-catalyzed conjugate addition of diethylzinc to nitroalkenes. Organic Letters. 6: 2689-91. PMID 15281745 DOI: 10.1021/Ol0491282 |
0.636 |
|
| 2004 |
Miller ML, Roller EE, Wu X, Leece BA, Goldmacher VS, Chari RV, Ojima I. Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies. Bioorganic & Medicinal Chemistry Letters. 14: 4079-82. PMID 15225730 DOI: 10.1016/J.Bmcl.2004.05.027 |
0.578 |
|
| 2004 |
Geng X, Geney R, Pera P, Bernacki RJ, Ojima I. Design and synthesis of de novo cytotoxic alkaloids through mimicking taxoid skeleton. Bioorganic & Medicinal Chemistry Letters. 14: 3491-4. PMID 15177459 DOI: 10.1016/J.Bmcl.2004.04.060 |
0.788 |
|
| 2004 |
Minderman H, Brooks TA, O'Loughlin KL, Ojima I, Bernacki RJ, Baer MR. Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023. Cancer Chemotherapy and Pharmacology. 53: 363-9. PMID 15060738 DOI: 10.1007/S00280-003-0745-2 |
0.311 |
|
| 2004 |
Hua Z, Vassar VC, Choi H, Ojima I. New biphenol-based, fine-tunable monodentate phosphoramidite ligands for catalytic asymmetric transformations. Proceedings of the National Academy of Sciences of the United States of America. 101: 5411-6. PMID 15020764 DOI: 10.1073/Pnas.0307101101 |
0.612 |
|
| 2004 |
Wu X, Ojima I. Tumor specific novel taxoid-monoclonal antibody conjugates. Current Medicinal Chemistry. 11: 429-38. PMID 14965224 DOI: 10.2174/0929867043455963 |
0.563 |
|
| 2004 |
Kuznetsova L, Ungureanu IM, Pepe A, Zanardi I, Wu X, Ojima I. Trifluoromethyl- and difluoromethyl-β-lactams as useful building blocks for the synthesis of fluorinated amino acids, dipeptides, and fluoro-taxoids Journal of Fluorine Chemistry. 125: 487-500. DOI: 10.1016/J.Jfluchem.2003.12.001 |
0.739 |
|
| 2003 |
Hua Z, Vassar VC, Ojima I. Synthesis of new chiral monodentate phosphite ligands and their use in catalytic asymmetric hydrogenation. Organic Letters. 5: 3831-4. PMID 14535721 DOI: 10.1021/Ol035343R |
0.627 |
|
| 2003 |
Geng X, Miller ML, Lin S, Ojima I. Synthesis of novel C2-C3'N-linked macrocyclic taxoids by means of highly regioselective Heck macrocyclization. Organic Letters. 5: 3733-6. PMID 14507217 DOI: 10.1021/Ol0354627 |
0.574 |
|
| 2003 |
Ojima I, Geney R. 109881 Aventis. Current Opinion in Investigational Drugs (London, England : 2000). 4: 737-40. PMID 12901234 |
0.759 |
|
| 2003 |
Ojima I, Geney R. BMS-184476 Bristol-Myers Squibb. Current Opinion in Investigational Drugs (London, England : 2000). 4: 732-6. PMID 12901233 |
0.758 |
|
| 2003 |
Ojima I, Ferlini C. New insights into drug resistance in cancer. Chemistry & Biology. 10: 583-4. PMID 12890528 DOI: 10.1016/S1074-5521(03)00152-2 |
0.33 |
|
| 2003 |
Ferlini C, Ojima I, Distefano M, Gallo D, Riva A, Morazzoni P, Bombardelli E, Mancuso S, Scambia G. Second generation taxanes: from the natural framework to the challenge of drug resistance. Current Medicinal Chemistry. Anti-Cancer Agents. 3: 133-8. PMID 12678907 DOI: 10.2174/1568011033353489 |
0.372 |
|
| 2003 |
Ojima I, Tsai C, Tzamarioudaki M, Bonafoux D. The Hydroformylation Reaction Cheminform. 34. DOI: 10.1002/0471264180.Or056.01 |
0.311 |
|
| 2002 |
Mizutani N, Chiou WH, Ojima I. New and efficient synthesis of azabicyclo[4.4.0]alkane amino acids by Rh-catalyzed cyclohydrocarbonylation. Organic Letters. 4: 4575-8. PMID 12489933 DOI: 10.1021/Ol026782D |
0.616 |
|
| 2002 |
Ojima I, Geng X, Wu X, Qu C, Borella CP, Xie H, Wilhelm SD, Leece BA, Bartle LM, Goldmacher VS, Chari RV. Tumor-specific novel taxoid-monoclonal antibody conjugates. Journal of Medicinal Chemistry. 45: 5620-3. PMID 12477344 DOI: 10.1021/Jm025540G |
0.776 |
|
| 2002 |
Geney R, Ungureanu lM, Li D, Ojima I. Overcoming multidrug resistance in taxane chemotherapy. Clinical Chemistry and Laboratory Medicine. 40: 918-25. PMID 12435109 DOI: 10.1515/Cclm.2002.161 |
0.807 |
|
| 2002 |
Ojima I, Vu AT, Lee SY, McCullagh JV, Moralee AC, Fujiwara M, Hoang TH. Rhodium-catalyzed silylcarbocyclization (SiCaC) and carbonylative silylcarbocyclization (CO-SiCaC) reactions of enynes. Journal of the American Chemical Society. 124: 9164-74. PMID 12149021 DOI: 10.1021/Ja0258982 |
0.743 |
|
| 2002 |
Ojima I, Geney R, Ungureanu IM, Li D. Medicinal chemistry and chemical biology of new generation taxane antitumor agents. Iubmb Life. 53: 269-74. PMID 12121008 DOI: 10.1080/15216540212658 |
0.805 |
|
| 2002 |
Jordan MA, Ojima I, Rosas F, Distefano M, Wilson L, Scambia G, Ferlini C. Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis. Chemistry & Biology. 9: 93-101. PMID 11841942 DOI: 10.1016/S1074-5521(01)00097-7 |
0.335 |
|
| 2002 |
Chuang CY, Vassar VC, Ma Z, Geney R, Ojima I. Electronic effects on the regio- and enantioselectivity of the asymmetric aminohydroxylation of O-substituted 4-hydroxy-2-butenoates. Chirality. 14: 151-62. PMID 11835558 DOI: 10.1002/Chir.10050 |
0.782 |
|
| 2002 |
Ojima I, Geng X, Lin S, Pera P, Bernacki RJ. Design, synthesis and biological activity of novel C2-C3' N-Linked macrocyclic taxoids. Bioorganic & Medicinal Chemistry Letters. 12: 349-52. PMID 11814794 DOI: 10.1016/S0960-894X(01)00747-8 |
0.577 |
|
| 2002 |
Ojima I. New cyclization reactions in organic syntheses Pure and Applied Chemistry. 74: 159-166. DOI: 10.1351/Pac200274010159 |
0.361 |
|
| 2002 |
Ojima I, Moralee AC, Vassar VC. Topics in Catalysis. 19: 89-99. DOI: 10.1023/A:1013837417361 |
0.318 |
|
| 2001 |
Miller ML, Ojima I. Chemistry and chemical biology of taxane anticancer agents. Chemical Record (New York, N.Y.). 1: 195-211. PMID 11895119 DOI: 10.1002/Tcr.1008 |
0.409 |
|
| 2001 |
Chibale K, Ojima I, Haupt H, Geng X, Pera P, Bernacki RJ. Modulation of human mammary cell sensitivity to paclitaxel by new quinoline sulfonamides. Bioorganic & Medicinal Chemistry Letters. 11: 2457-60. PMID 11549446 DOI: 10.1016/S0960-894X(01)00462-0 |
0.604 |
|
| 2001 |
Vredenburg MR, Ojima I, Veith J, Pera P, Kee K, Cabral F, Sharma A, Kanter P, Greco WR, Bernacki RJ. Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance. Journal of the National Cancer Institute. 93: 1234-45. PMID 11504769 DOI: 10.1093/Jnci/93.16.1234 |
0.349 |
|
| 2001 |
Crabtree DV, Ojima I, Geng X, Adler AJ. Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site. Bioorganic & Medicinal Chemistry. 9: 1967-76. PMID 11504633 DOI: 10.1016/S0968-0896(01)00103-1 |
0.512 |
|
| 2001 |
Bonafoux D, Hua Z, Wang B, Ojima I. Design and synthesis of new fluorinated ligands for the rhodium-catalyzed hydroformylation of alkenes in supercritical CO2 and fluorous solvents Journal of Fluorine Chemistry. 112: 101-108. DOI: 10.1016/S0022-1139(01)00473-0 |
0.599 |
|
| 2000 |
Ferlini C, Distefano M, Pignatelli F, Lin S, Riva A, Bombardelli E, Mancuso S, Ojima I, Scambia G. Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors British Journal of Cancer. 83: 1762-1768. PMID 11104578 DOI: 10.1054/Bjoc.2000.1500 |
0.341 |
|
| 2000 |
Ojima I, Lin S, Slater JC, Wang T, Pera P, Bernacki RJ, Ferlini C, Scambia G. Syntheses and biological activity of C-3'-difluoromethyl-taxoids. Bioorganic & Medicinal Chemistry. 8: 1619-28. PMID 10976509 DOI: 10.1016/S0968-0896(00)00093-6 |
0.379 |
|
| 2000 |
Lin S, Geng X, Qu C, Tynebor R, Gallagher DJ, Pollina E, Rutter J, Ojima I. Synthesis of highly potent second-generation taxoids through effective kinetic resolution coupling of racemic beta-lactams with baccatins. Chirality. 12: 431-41. PMID 10824166 DOI: 10.1002/(Sici)1520-636X(2000)12:5/6<431::Aid-Chir24>3.0.Co;2-M |
0.566 |
|
| 2000 |
Lin S, Ojima I. Recent strategies in the development of taxane anticancer drugs Expert Opinion On Therapeutic Patents. 10: 869-889. DOI: 10.1517/13543776.10.6.869 |
0.381 |
|
| 2000 |
Ojima I, Lee SY. Rhodium-catalyzed novel carbonylative carbotricyclization of enediynes [8] Journal of the American Chemical Society. 122: 2385-2386. DOI: 10.1021/Ja993977G |
0.751 |
|
| 2000 |
Ojima I, Lin S, Inoue T, Miller ML, Borella CP, Geng X, Walsh JJ. Macrocycle formation by ring-closing metathesis. Application to the syntheses of novel macrocyclic taxoids Journal of the American Chemical Society. 122: 5343-5353. DOI: 10.1021/Ja000293W |
0.799 |
|
| 1999 |
Ojima I, Wang T, Miller ML, Lin S, Borella CP, Geng X, Pera P, Bernacki RJ. Synthesis and structure-activity relationships of new second-generation taxoids. Bioorganic & Medicinal Chemistry Letters. 9: 3423-8. PMID 10617084 DOI: 10.1016/S0960-894X(99)00629-0 |
0.803 |
|
| 1999 |
Ojima I, Chakravarty S, Inoue T, Lin S, He L, Horwitz SB, Kuduk SD, Danishefsky SJ. A common pharmacophore for cytotoxic natural products that stabilize microtubules Proceedings of the National Academy of Sciences of the United States of America. 96: 4256-4261. PMID 10200249 DOI: 10.1073/Pnas.96.8.4256 |
0.325 |
|
| 1999 |
Nakano M, Tominaga K, Saito S, Kirikae F, Lin S, Fumero CL, Ojima I, Kirikae T. Lipopolysaccharide- and paclitaxel (Taxol)-induced tolerance in murine peritoneal macrophages Innate Immunity. 5: 102-106. DOI: 10.1177/09680519990050011201 |
0.745 |
|
| 1999 |
Ojima I, Vidal ES. Extremely Regioselective Intramolecular Silylformylation of Bis(silylamino)alkynes Organometallics. 18: 5103-5107. DOI: 10.1021/Om9904549 |
0.318 |
|
| 1999 |
Ojima I, Vu AT, McCullagh JV, Kinoshita A. Rhodium-catalyzed intramolecular silylcarbotricyclization (SiCaT) of triynes [7] Journal of the American Chemical Society. 121: 3230-3231. DOI: 10.1021/Ja9815529 |
0.335 |
|
| 1999 |
Ojima I, Inoue T, Chakravarty S. Enantiopure fluorine-containing taxoids: Potent anticancer agents and versatile probes for biomedical problems Journal of Fluorine Chemistry. 97: 3-10. DOI: 10.1016/S0022-1139(99)00058-5 |
0.371 |
|
| 1998 |
Ojima I, Bounaud PY, Takeuchi C, Pera P, Bernacki RJ. New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells. Bioorganic & Medicinal Chemistry Letters. 8: 189-94. PMID 9871652 DOI: 10.1016/S0960-894X(97)10218-9 |
0.385 |
|
| 1998 |
Ojima I, Bounaud P, Oderda CF. Recent strategies for the treatment of multi-drug resistance in cancer cells Expert Opinion On Therapeutic Patents. 8: 1587-1598. DOI: 10.1517/13543776.8.12.1587 |
0.345 |
|
| 1998 |
Ojima I, Vidal ES. Rhodium-Catalyzed Cyclohydrocarbonylation: Application to the Synthesis of (+)-Prosopinine and (−)-Deoxoprosophylline† Journal of Organic Chemistry. 63: 7999-8003. DOI: 10.1021/Jo9815608 |
0.309 |
|
| 1998 |
Ojima I, Lin S, Chakravarty S, Fenoglio I, Park YH, Sun C, Appendino G, Pera P, Veith JM, Bernacki RJ. Syntheses and Structure−Activity Relationships of Novel Nor-seco Taxoids The Journal of Organic Chemistry. 63: 1637-1645. DOI: 10.1021/Jo971953R |
0.346 |
|
| 1998 |
Ojima I, Lin S. Efficient Asymmetric Syntheses of β-Lactams Bearing a Cyclopropane or an Epoxide Moiety and Their Application to the Syntheses of Novel Isoserines and Taxoids Journal of Organic Chemistry. 63: 224-225. DOI: 10.1021/Jo971908J |
0.314 |
|
| 1998 |
Ojima I, Zhu J, Vidal ES, Kass DF. Silylcarbocyclizations of 1,6-Diynes Journal of the American Chemical Society. 120: 6690-6697. DOI: 10.1021/Ja980907L |
0.303 |
|
| 1998 |
Ojima I, Iula DM, Tzamarioudaki M. Efficient syntheses of functionalized piperidines through extremely regioselective Rh-catalyzed cyclohydrocarbonylation of amido-ω,ω'-dienes Tetrahedron Letters. 39: 4599-4602. DOI: 10.1016/S0040-4039(98)00848-X |
0.354 |
|
| 1998 |
Ojima I, Wang H, Wang T, Ng EW. New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method Tetrahedron Letters. 39: 923-926. DOI: 10.1016/S0040-4039(97)10677-3 |
0.3 |
|
| 1998 |
Distefano M, Scambia G, Ferlini C, Gaggini C, De Vincenzo R, Riva A, Bombardelli E, Ojima I, Fattorossi A, Benedetti Panici P, Mancuso S. Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.Int. J. Cancer,72, 844–850 (1997) International Journal of Cancer. 76: 164-164. DOI: 10.1002/(Sici)1097-0215(19980330)76:1<164::Aid-Ijc25>3.0.Co;2-B |
0.33 |
|
| 1997 |
Ojima I, Slater JC. Synthesis of novel 3'-trifluoromethyl taxoids through effective kinetic resolution of racemic 4-CF3-beta-lactams with baccatins. Chirality. 9: 487-94. PMID 9329178 DOI: 10.1002/(Sici)1520-636X(1997)9:5/6<487::Aid-Chir15>3.0.Co;2-K |
0.319 |
|
| 1997 |
Distefano M, Scambia G, Ferlini C, Gaggini C, De Vincenzo R, Riva A, Bombardelli E, Ojima I, Fattorossi A, Panici PB, Mancuso S. Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells. International Journal of Cancer. 72: 844-50. PMID 9311603 DOI: 10.1002/(Sici)1097-0215(19970904)72:5<844::Aid-Ijc22>3.0.Co;2-7 |
0.34 |
|
| 1997 |
Ojima I, Kuduk SD, Pera P, Veith JM, Bernacki RJ. Synthesis and structure-activity relationships of nonaromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity. Journal of Medicinal Chemistry. 40: 279-85. PMID 9022794 DOI: 10.1021/Jm9606711 |
0.318 |
|
| 1997 |
Ojima I, Slater JC, Kuduk SD, Takeuchi CS, Gimi RH, Sun CM, Park YH, Pera P, Veith JM, Bernacki RJ. Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III. Journal of Medicinal Chemistry. 40: 267-78. PMID 9022793 DOI: 10.1021/Jm960563E |
0.354 |
|
| 1997 |
Ojima I, Slater JC, Pera P, Veith JM, Abouabdellah A, Bégué JP, Bernacki RJ. Synthesis and biological activity of novel 3'-trifluoromethyl taxoids Bioorganic and Medicinal Chemistry Letters. 7: 133-138. DOI: 10.1016/S0960-894X(96)00595-1 |
0.389 |
|
| 1996 |
Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ. Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells. Journal of Medicinal Chemistry. 39: 3889-96. PMID 8831755 DOI: 10.1021/Jm9604080 |
0.363 |
|
| 1996 |
Ojima I, Machnik D, Donovan RJ, Mneimne O. Silylcyclocarbonylation (SiCCa) of alkynylamines catalyzed by rhodium complexes Inorganica Chimica Acta. 251: 299-307. DOI: 10.1016/S0020-1693(97)82717-X |
0.324 |
|
| 1996 |
Ojima I, McCullagh JV, Shay WR. New cascade silylcarbocyclization (SiCaC) of enediynes Journal of Organometallic Chemistry. 521: 421-423. DOI: 10.1016/0022-328X(96)06359-0 |
0.301 |
|
| 1995 |
Sharma A, Straubinger RM, Ojima I, Bernacki RJ. Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice Journal of Pharmaceutical Sciences. 84: 1400-1404. PMID 8748320 DOI: 10.1002/Jps.2600841204 |
0.326 |
|
| 1995 |
Ojima I, Tzamarioudaki M, Eguchi M. New and Efficient Route to Pipecolic Acid Derivatives by Means of Rh-Catalyzed Intramolecular Cyclohydrocarbonylation Journal of Organic Chemistry. 60: 7078-7079. DOI: 10.1021/Jo00127A002 |
0.319 |
|
| 1995 |
Ojima I, Vidal E, Tzamarioudaki M, Matsuda I. Extremely Regioselective Intramolecular Silylformylation of Alkynes Journal of the American Chemical Society. 117: 6797-6798. DOI: 10.1021/Ja00130A027 |
0.325 |
|
| 1995 |
Ojima I, Ng EW, Sun CM. Novel route to hydroxy(keto)ethylene dipeptide isosteres through the reaction of N-tBOC-β-lactams with enolates Tetrahedron Letters. 36: 4547-4550. DOI: 10.1016/0040-4039(95)00825-W |
0.345 |
|
| 1994 |
Ojima I, Duclos O, Zucco M, Bissery MC, Combeau C, Vrignaud P, Riou JF, Lavelle F. Synthesis and structure-activity relationships of new antitumor taxoids. Effects of cyclohexyl substitution at the C-3' and/or C-2 of taxotere (docetaxel). Journal of Medicinal Chemistry. 37: 2602-8. PMID 7914541 DOI: 10.1021/Jm00042A013 |
0.333 |
|
| 1994 |
Ojima I, Fenoglio I, Park YH, Sun C, Appendino G, Pera P, Bernacki RJ. Synthesis and Structure-Activity Relationships of Novel Nor-Seco Analogs of Taxol and Taxotere Journal of Organic Chemistry. 59: 515-517. DOI: 10.1021/Jo00082A003 |
0.37 |
|
| 1994 |
Ojima I, Fenoglio I, Park YH, Pera P, Bernacki RJ. Synthesis and biological activity of 14-hydroxydocetaxel Bioorganic & Medicinal Chemistry Letters. 4: 1571-1576. DOI: 10.1016/S0960-894X(01)80568-0 |
0.335 |
|
| 1994 |
Ojima I, Duclos O, Kuduk SD, Sun CM, Slater JC, Lavelle F, Veith JM, Bernacki RJ. Synthesis and biological activity of 3′-alkyl- and 3′-alkenyl-3′-dephenyldocetaxels Bioorganic and Medicinal Chemistry Letters. 4: 2631-2634. DOI: 10.1016/S0960-894X(01)80298-5 |
0.369 |
|
| 1993 |
Ojima I, Sun CM, Zucco M, Park YH, Duclos O, Kuduk S. A highly efficient route to taxotere by the β-Lactam Synthon Method Tetrahedron Letters. 34: 4149-4152. DOI: 10.1016/S0040-4039(00)60514-2 |
0.344 |
|
| 1993 |
Ojima I, Donovan RJ, Eguchi M, Shay WR, Ingallina P, Korda A, Zeng Q. Silylformylation catalyzed by Rh and Rh-Co mixed metal complexes and its application to the synthesis of pyrrolizidine alkaloids Tetrahedron. 49: 5431-5444. DOI: 10.1016/S0040-4020(01)87260-4 |
0.321 |
|
| 1993 |
Zhang Z, Ojima I. Syntheses of nitrogen heterocycles by means of amine-directed carbonylation and hydrocarbonylation Journal of Organometallic Chemistry. 454: 281-289. DOI: 10.1016/0022-328X(93)83252-Q |
0.308 |
|
| 1992 |
Ojima I, Pei Y. Novel rearrangements of chiral 3-oxazolidinylazetidin-2-ones Tetrahedron Letters. 33: 887-890. DOI: 10.1016/S0040-4039(00)91567-3 |
0.343 |
|
| 1992 |
Ojima I, Habus I, Zhao M, Zucco M, Park YH, Sun CM, Brigaud T. New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of β-lactam synthon method Tetrahedron. 48: 6985-7012. DOI: 10.1016/S0040-4020(01)91210-4 |
0.323 |
|
| 1992 |
Ojima I, Hoon Park Y, Ming Sun C, Brigaud T, Zhao M. New and efficient routes to norstatine and its analogs with high enantiomeric purity by β-Lactam Synthon Method Tetrahedron Letters. 33: 5737-5740. DOI: 10.1016/0040-4039(92)89019-9 |
0.305 |
|
| 1991 |
Ojima I, Korda A, Shay WR. New synthesis of nitrogen heterocycles through amide-directed hydrocarbonylation of alkenamides catalyzed by rhodium complexes Journal of Organic Chemistry. 56: 2024-2030. DOI: 10.1021/Jo00006A013 |
0.306 |
|
| 1991 |
Ojima I, Habus I, Zhao M, Georg GI, Jayasinghe LR. Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R,3S)-3-phenylisoserine, and its analogues via chiral 3-hydroxy-4-aryl-β-lactams through chiral ester enolate-imine cyclocondensation Journal of Organic Chemistry. 56: 1681-1683. DOI: 10.1021/Jo00005A003 |
0.316 |
|
| 1991 |
Ojima I. Design and synthesis of novel trifluoromethyl-containing peptides and their use as enzyme inhibitors Journal of Fluorine Chemistry. 54: 187. DOI: 10.1016/S0022-1139(00)83697-0 |
0.3 |
|
| 1991 |
Ojima I, Zhang Z. Amide-directed hydrocarbonylation of N-alkenylamides and α-alkenyllactams Journal of Organometallic Chemistry. 417: 253-276. DOI: 10.1016/0022-328X(91)80177-L |
0.33 |
|
| 1990 |
Ojima I. Chapter IV.1 New Carbonylations by Means of Transition Metal Catalysts Studies in Surface Science and Catalysis. 54: 301-321. DOI: 10.1016/S0167-2991(08)60046-4 |
0.31 |
|
| 1990 |
Ojima I, Pei Y. Asymmetric synthesis with chiral β-lactams. Highly stereoselective alkylation and aldol reaction of a chiral 3-amino-4-styryl-β-lactam. Tetrahedron Letters. 31: 977-980. DOI: 10.1016/S0040-4039(00)94407-1 |
0.312 |
|
| 1989 |
Ojima I, Korda A. New routes to nitrogen heterocycles through intramolecular amidocarbonylation of alkenamides catalyzed by rhodium complexes Tetrahedron Letters. 30: 6283-6286. DOI: 10.1016/S0040-4039(01)93873-0 |
0.343 |
|
| 1987 |
Brandstadter SM, Ojima I, Herai K. Reactions of ketene silyl acetals with imine-complexes of titanium tetrachloride. New and convenient routes to 5,6-dihydro-2-pyridones and 5-amino-2-alkenoates Tetrahedron Letters. 28: 613-616. DOI: 10.1016/S0040-4039(00)95794-0 |
0.331 |
|
| 1985 |
Ojima I, Yamato T, Nakahashi K. Synthesis of novel chiral bisazetidines by the hydroalane reduction of bis-beta-lactams Tetrahedron Letters. 26: 2035-2038. DOI: 10.1016/S0040-4039(00)94772-5 |
0.307 |
|
| 1984 |
Ojima I. Homogeneous asymmetric catalysis by means of chiral rhodium complexes Pure and Applied Chemistry. 56: 99-110. DOI: 10.1351/Pac198456010099 |
0.319 |
|
| 1984 |
Fuchikami T, Ojima I. Transition-metal complex catalyzed polyfluoroalkylation. II. Novel and convenient route to 3-polyfluoroalkylprop-1-enes through the reaction of polyfluoroalkyl halides with allylsilanes Tetrahedron Letters. 25: 307-308. DOI: 10.1016/S0040-4039(00)99869-1 |
0.308 |
|
| 1984 |
Ojima I, Fuchikami T, Yatabe M. The reactions of hydrosilanes with trifluoropropene and pentafluorostyrene catalyzed by ruthenium, rhodium and palladium complexes Journal of Organometallic Chemistry. 260: 335-346. DOI: 10.1016/S0022-328X(00)99483-X |
0.306 |
|
| 1983 |
Hirai K, Ojima I. Coupling reactions of vinylketene silyl acetals promoted by titanium tetrachloride Tetrahedron Letters. 24: 785-788. DOI: 10.1016/S0040-4039(00)81527-0 |
0.303 |
|
| 1983 |
Fuchikami T, Ojima I. Direct perfluoroalkylation of functionalized benzenes with perfluoroalkyl halides and copper bronze Journal of Fluorine Chemistry. 22: 541-556. DOI: 10.1016/S0022-1139(00)81229-4 |
0.309 |
|
| 1982 |
OJIMA I, HATANAKA N. Journal of Synthetic Organic Chemistry, Japan. 40: 209-217. DOI: 10.5059/Yukigoseikyokaishi.40.209 |
0.305 |
|
| 1982 |
Fuchikami T, Ojima I. New and direct route to 5-trifluoromethyl-5,6-dihydrouracils by means of palladium complex catalyzed “ureidocarbonylation” of 2-bromo-3,3,3-trifluoropropene Tetrahedron Letters. 23: 4099-4100. DOI: 10.1016/S0040-4039(00)88357-4 |
0.323 |
|
| 1982 |
Hatanaka N, Abe R, Ojima I. β‐LACTAM AS SYNTHETIC INTERMEDIATE: SYNTHESIS OF LEUCINE‐ENKEPHALIN Cheminform. 13. DOI: 10.1002/Chin.198209322 |
0.314 |
|
| 1981 |
Ojima I, Inaba S, Nagai M. Convenient Synthesis of β-Lactams by the Reaction of Ketene Silyl Acetals with Schiff Bases Promoted by Titanium(IV) Chloride Synthesis. 1981: 545-547. DOI: 10.1055/S-1981-29520 |
0.317 |
|
| 1981 |
Fuchikami T, Ojima I. Reaction of (bromodifluoromethyl)phenyldimethylsilane with organometallic reagents Journal of Organometallic Chemistry. 212: 145-153. DOI: 10.1016/S0022-328X(00)81910-5 |
0.314 |
|
| 1980 |
Ojima I, Yoda N. N-carbamoyl-4-diphenylphosphino-2-diphenylphosphinomethylpyrrolidines(CAPP). Efficient new chiral ligands for asymmetric hydrogenation Tetrahedron Letters. 21: 1051-1054. DOI: 10.1016/S0040-4039(00)78836-8 |
0.311 |
|
| 1980 |
Ojima I, Inaba S. Asymmetric synthesis of β-lactams. II. Highly effective asymmetric induction by means of “titanium template” Tetrahedron Letters. 21: 2081-2084. DOI: 10.1016/S0040-4039(00)71492-4 |
0.322 |
|
| 1980 |
Ojima I, Inaba S. Asymmetric synthesis of β-lactams. I. The reaction of dimethylketene silyl acetal with (S)-alkylidene(1-arylethyl)amines promoted by titanium tetrachloride Tetrahedron Letters. 21: 2077-2080. DOI: 10.1016/S0040-4039(00)71491-2 |
0.315 |
|
| 1980 |
Ojima I, Suzuki T. Asymmetric synthesis of dipeptides by means of homogeneous hydrogenation catalyzed by chiral rhodium complexes Tetrahedron Letters. 21: 1239-1242. DOI: 10.1016/S0040-4039(00)71381-5 |
0.3 |
|
| 1980 |
Ojima I, Kogure T. The asymmetric hydrogenation of α-keto esters catalyzed by rhodium(I) complexes with chiral diphosphine ligands. On the catalytic cycles and the mechanism of asymmetric induction Journal of Organometallic Chemistry. 195: 239-248. DOI: 10.1016/S0022-328X(00)90008-1 |
0.318 |
|
| 1980 |
Ojima I, Suga S, Abe R. A novel route to dipeptide and its derivative by means of the palladium catalyzed facile cleavage of 1-(1-methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones Tetrahedron Letters. 21: 3907-3910. DOI: 10.1016/0040-4039(80)80213-9 |
0.342 |
|
| 1979 |
OJIMA I, FUCHIKAMI T. Journal of Synthetic Organic Chemistry, Japan. 37: 739-754. DOI: 10.5059/Yukigoseikyokaishi.37.739 |
0.318 |
|
| 1979 |
Inaba S, Ojima I, Yoshida K, Nagai M. Reactions of silyl enol ethers and ketene silyl ketals with isocyanates Journal of Organometallic Chemistry. 164: 123-134. DOI: 10.1016/S0022-328X(00)86696-6 |
0.328 |
|
| 1979 |
Inaba S, Ojima I. Reaction of trimethylsilyl cyanide with isocyanates and carbodiimides Journal of Organometallic Chemistry. 169: 171-184. DOI: 10.1016/S0022-328X(00)81156-0 |
0.326 |
|
| 1978 |
OJIMA I, INABA S. Journal of Synthetic Organic Chemistry, Japan. 36: 610-615. DOI: 10.5059/Yukigoseikyokaishi.36.610 |
0.336 |
|
| 1978 |
Ojima I, Kogure T, Achiwa K. EFFECTIVE ASYMMETRIC HYDROGENATION OF ITACONIC ACID CATALYZED BY NEUTRAL AND CATIONIC RHODIUM(I) COMPLEXES WITH CHIRAL PYRROLIDINODIPHOSPHINE LIGAND Chemistry Letters. 7: 567-568. DOI: 10.1246/Cl.1978.567 |
0.303 |
|
| 1978 |
Ojima I, Kumagai M. Regioselective hydrosilylation of 1,3-dienes catalyzed by phosphine complexes of palladium and rhodium Journal of Organometallic Chemistry. 157: 359-372. DOI: 10.1016/S0022-328X(00)91720-0 |
0.336 |
|
| 1978 |
ACHIWA K, KOGURE T, OJIMA I. ChemInform Abstract: ASYMMETRIC REACTIONS CATALYZED BY CHIRAL METAL COMPLEXES. VIII. HIGHLY EFFECTIVE CATALYTIC ASYMMETRIC SYNTHESIS OF R-(-)-PANTOLACTONE Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197840196 |
0.311 |
|
| 1977 |
Ojima I, Kogure T, Achiwa K. Effective homogeneous hydrogenation of α-keto esters catalysed by neutral rhodium(I) complexes with phosphine ligands and application to the asymmetric synthesis of lactates Journal of the Chemical Society, Chemical Communications. 428-430. DOI: 10.1039/C39770000428 |
0.301 |
|
| 1977 |
Ojima I, Kogure T, Kumagai M. Reduction of carbonyl compounds via hydrosilylation. 3. Asymmetric reduction of keto esters via hydrosilylation catalyzed by a rhodium complex with chiral phosphine ligands The Journal of Organic Chemistry. 42: 1671-1679. DOI: 10.1021/Jo00430A001 |
0.322 |
|
| 1977 |
Ojima I, Kumagai M, Miyazawa Y. 3-TMS-cyclopentene-1 a new reagent for the synthesis of cyclopentene derivatives Tetrahedron Letters. 18: 1385-1388. DOI: 10.1016/S0040-4039(01)93050-3 |
0.315 |
|
| 1977 |
Inaba S, Ojima I. Novel and convenient route to substituted succinates. The dimerization of ketene silyl acetals promoted by titanium tetrachloride Tetrahedron Letters. 18: 2009-2012. DOI: 10.1016/S0040-4039(01)83666-2 |
0.324 |
|
| 1977 |
Ojima I, Inaba S, Yoshida K. New and effective route to β-lactams. The reaction of ketene silyl acetals with schiff bases promoted by titanium tetrachloride Tetrahedron Letters. 18: 3643-3646. DOI: 10.1016/S0040-4039(01)83315-3 |
0.303 |
|
| 1977 |
Ojima I. Stereochemistry of the regiospecific hydrosilylation of isoprene catalyzed by a phosphine-palladium complex Journal of Organometallic Chemistry. 134: C1-C5. DOI: 10.1016/S0022-328X(00)93621-0 |
0.329 |
|
| 1977 |
Ojima I, Inaba S. Reduction of isocyanates and carbodiimides via hydrosilylation Journal of Organometallic Chemistry. 140: 97-111. DOI: 10.1016/S0022-328X(00)84400-9 |
0.3 |
|
| 1977 |
Ojima I, Yamamoto K, Kumada M. Asymmetric Hydrosilylation by Means of Homogeneous Catalysts with Chiral Ligands Cheminform. 9: 185-228. DOI: 10.1007/978-94-010-1199-0_3 |
0.324 |
|
| 1977 |
Ojima I, Yoshida K, Inaba S. ASYMMETRIC CROSS ALDOL SYNTHESIS. ASYMMETRIC ADDITION OF SILYL ENOL ETHER AND KETENE SILYL ACETAL TO α-KETO ESTERS Chemistry Letters. 6: 429-432. DOI: 10.1002/Chin.197805092 |
0.311 |
|
| 1977 |
Ojima I, Kogure T, Achiwa K. EFFECTIVE HOMOGENEOUS HYDROGENATION OF α‐KETO ESTERS CATALYZED BY NEUTRAL RHODIUM(I) COMPLEXES WITH PHOSPHINE LIGANDS AND APPLICATION TO THE ASYMMETRIC SYNTHESIS OF LACTATES Cheminform. 8. DOI: 10.1002/Chin.197746114 |
0.304 |
|
| 1976 |
Ojima I, Miyazawa Y, Kumagai M. Asymmetric addition of allyltrimethylsilane to (–)-menthyl pyruvate and phenylglyoxylate Journal of the Chemical Society, Chemical Communications. 927-928. DOI: 10.1039/C39760000927 |
0.3 |
|
| 1975 |
OJIMA I, NIHONYANAGI M, KOGURE T, KUMAGAI M, HORIUCI S, NAKATSUGAWA K, NAGAI Y. ChemInform Abstract: REDUCTION OF CARBONYL COMPOUNDS VIA HYDROSILYLATION PART 1, HYDROSILYLATION OF CARBONYL COMPOUNDS CATALYZED BY TRIS(TRIPHENYLPHOSPHINE)CHLORORHODIUM Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197551147 |
0.32 |
|
| 1974 |
Ojima I, Nagai Y. ASYMMETRIC REDUCTION OF KETONES VIA HYDROSILYLATION CATALYZED BY A RHODIUM(I) COMPLEX WITH CHIRAL PHOSPHINE LIGANDS. II. ON THE MECHANISM OF THE INDUCTION OF ASYMMETRY Chemistry Letters. 3: 223-228. DOI: 10.1246/Cl.1974.223 |
0.31 |
|
| 1974 |
Ojima I, Inaba S, Nagai Y. Reaction of trimethylsilyl cyanide with isocyanates Journal of the Chemical Society, Chemical Communications. 826-827. DOI: 10.1039/C39740000826 |
0.317 |
|
| 1974 |
Ojima I, Kumagai M, Nagai Y. The stereochemistry of the addition of hydrosilanes to alkyl acetylenes catalyzed by tris(triphenylphosphine)-chlororhodium Journal of Organometallic Chemistry. 66: C14-C16. DOI: 10.1016/S0022-328X(00)93873-7 |
0.33 |
|
| 1973 |
Ojima I, Inaba S, Nagai Y. A novel route to formamides and their derivatives. Reduction of isocyanates via hydrosilylation catalyzed by palladium Tetrahedron Letters. 14: 4363-4366. DOI: 10.1016/S0040-4039(01)87223-3 |
0.341 |
|
| 1973 |
Ojima I, Inaba S, Nagai Y. A novel route to 2-carbamoylcycloalkanones by the addition reaction of silyl enol ethers to isocyanates Tetrahedron Letters. 14: 4271-4272. DOI: 10.1016/S0040-4039(01)87167-7 |
0.333 |
|
| 1973 |
Ojima I, Nagai Y. Reactions of triethylsilyl thiophenoxide with ketones having an electron-with-drawing group on the α-carbon Journal of Organometallic Chemistry. 57: C42-C44. DOI: 10.1016/S0022-328X(00)86579-1 |
0.327 |
|
| 1973 |
Ojima I, Akiba K, Inamoto N. Reactions of Diphenylphosphinothioyl Isothiocyanate and Related Compounds with Some Nucleophiles and Carbodiimides Bulletin of the Chemical Society of Japan. 46: 2559-2562. DOI: 10.1002/Chin.197344366 |
0.304 |
|
| 1972 |
Kondo K, Ojima I. Reactions of carbenes bearing sulphide linkages at the δ-position Journal of the Chemical Society, Chemical Communications. 860-861. DOI: 10.1039/C39720000860 |
0.338 |
|
| 1972 |
Kondo K, Negishi A, Ojima I. Acid-catalyzed ring opening reactions of episulfoxides Journal of the American Chemical Society. 94: 5786-5793. DOI: 10.1021/Ja00771A042 |
0.309 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2000 |
Kirikae T, Ojima I, Fuero-Oderda C, Lin S, Kirikae F, Hashimoto M, Nakano M. Structural significance of the acyl group at the C-10 position and the A ring of the taxane core of paclitaxel for inducing nitric oxide and tumor necrosis factor production by murine macrophages Febs Letters. 478: 221-226. PMID 10930572 DOI: 10.1016/S0014-5793(00)01858-5 |
0.3 |
|
| 1992 |
Ojima I, Donovan RJ, Shay WR. Silylcarbocyclization reactions catalyzed by rhodium and rhodium-cobalt complexes Journal of the American Chemical Society. 114: 6580-6582. DOI: 10.1021/Ja00042A061 |
0.299 |
|
| 1987 |
Ojima I. New approaches to the synthesis of organofluorine compounds by means of homogeneous catalysis Journal of Fluorine Chemistry. 35: 31. DOI: 10.1016/0022-1139(87)95023-8 |
0.299 |
|
| 1998 |
Hayashi Y, Katada J, Harada T, Tachiki A, Iijima K, Takiguchi Y, Muramatsu M, Miyazaki H, Asari T, Okazaki T, Sato Y, Yasuda E, Yano M, Uno I, Ojima I. GPIIb/IIIa integrin antagonists with the new conformational restriction unit, trisubstituted beta-amino acid derivatives, and a substituted benzamidine structure. Journal of Medicinal Chemistry. 41: 2345-60. PMID 9632368 DOI: 10.1021/Jm980126V |
0.299 |
|
| 2008 |
Ojima I. Modern molecular approaches to drug design and discovery. Accounts of Chemical Research. 41: 2-3. PMID 18193819 DOI: 10.1021/Ar700158C |
0.298 |
|
| 1994 |
Ojima I, Fracchiolla DA, Donovan RJ, Banerji P. Silylcarbobicyclization of 1,6-Diynes: A Novel Catalytic Route to Bicyclo[3.3.0]octenones Journal of Organic Chemistry. 59: 7594-7595. DOI: 10.1021/Jo00104A012 |
0.298 |
|
| 2000 |
Lin S, Fang K, Hashimoto M, Nakanishi K, Ojima I. Design and synthesis of a novel photoaffinity taxoid as a potential probe for the study of paclitaxel-microtubules interactions Tetrahedron Letters. 41: 4287-4290. DOI: 10.1016/S0040-4039(00)00627-4 |
0.298 |
|
| 1998 |
Ojima I, Wang T, Delaloge F. Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids Tetrahedron Letters. 39: 3663-3666. DOI: 10.1016/S0040-4039(98)00643-1 |
0.297 |
|
| 2016 |
Mohelnikova-Duchonova B, Kocik M, Duchonova B, Brynychova V, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Ojima I, Hughes DJ, Doherty JE, Murray HA, Crockard MA, Lemstrova R, et al. Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216. The Pharmacogenomics Journal. PMID 27573236 DOI: 10.1038/Tpj.2016.55 |
0.297 |
|
| 2014 |
Moriwaki H, Resch D, Li H, Ojima I, Takeda R, Aceña JL, Soloshonok VA. Synthesis and stereochemical assignments of diastereomeric Ni(II) complexes of glycine Schiff base with (R)-2-(N-{2-[N-alkyl-N-(1-phenylethyl)amino]acetyl}amino)benzophenone; a case of configurationally stable stereogenic nitrogen. Beilstein Journal of Organic Chemistry. 10: 442-8. PMID 24605164 DOI: 10.3762/Bjoc.10.41 |
0.297 |
|
| 1996 |
Ojima I, Kass DF, Zhu J. New and Efficient Catalytic Route to Bicyclo[3.3.0]octa-1,5-dien-3-ones Organometallics. 15: 5191-5195. DOI: 10.1021/Om960471N |
0.297 |
|
| 1973 |
Ojima I, Kondo K. Intramolecular Participation of Sulfide Linkage in the Reactivity of Carbene and Diazoalkanes. I. Alkylcarbenes and Diazoalkanes Bearing Alkylthio, Arylthio, and Allylthio Groups ona-Carbon Bulletin of the Chemical Society of Japan. 46: 1539-1545. DOI: 10.1246/Bcsj.46.1539 |
0.296 |
|
| 1992 |
Ojima I, Kato K, Jameison FA, Conway J, Nakahashi K, Hagiwara M, Miyamae T, Radunz HE. New potent enkephalin analogs containing trifluoromethylamino acid residues Bioorganic & Medicinal Chemistry Letters. 2: 219-222. DOI: 10.1016/S0960-894X(01)81068-4 |
0.296 |
|
| 2015 |
Knudson SE, Awasthi D, Kumar K, Carreau A, Goullieux L, Lagrange S, Vermet H, Ojima I, Slayden RA. Cell division inhibitors with efficacy equivalent to isoniazid in the acute murine Mycobacterium tuberculosis infection model. The Journal of Antimicrobial Chemotherapy. PMID 26245639 DOI: 10.1093/Jac/Dkv226 |
0.296 |
|
| 1972 |
Kondo K, Ojima I. CYCLOADDITIONS OF DIAZOALKMTES TO VINYL AND ALLYL SULFIDE SYSTEMS Chemistry Letters. 1: 771-774. DOI: 10.1246/Cl.1972.771 |
0.295 |
|
| 1984 |
Fuchikami T, Ojima I. Transition-metal complex catalyzed polyfluoroalkylation. I. Facile addition of polyfluoroalkyl halides to carbon-carbon multiple bonds Tetrahedron Letters. 25: 303-306. DOI: 10.1016/S0040-4039(00)99868-X |
0.294 |
|
| 1974 |
Ojima I, Kogure T, Nagai Y. Asymmetric reduction of α-keto esters via hydrosilylation catalyzed by a rhodium(I) complex with chiral phosphin ligands Tetrahedron Letters. 15: 1889-1892. DOI: 10.1016/S0040-4039(01)82586-7 |
0.294 |
|
| 1985 |
Ojima I, Hirai K, Fujita M, Fuchikami T. New synthetic route to N-acyl-α-amino acids via amidocarbonylation by means of homogeneous binary catalyst systems Journal of Organometallic Chemistry. 279: 203-214. DOI: 10.1016/0022-328X(85)87018-2 |
0.293 |
|
| 1983 |
KOGURE T, OJIMA I. ChemInform Abstract: REDUCTION OF CARBONYL COMPOUNDS VIA HYDROSILYLATION. V. SYNTHESIS OF OPTICALLY ACTIVE ALLYLIC ALCOHOLS VIA REGIOSELECTIVE ASYMMETRIC HYDROSILYLATION Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198301128 |
0.293 |
|
| 1975 |
Ojima I, Inaba S, Nagai Y. Reaction of trimethylsilyl cyanide with carbodiimides Journal of Organometallic Chemistry. 99: C5-C7. DOI: 10.1016/S0022-328X(00)86374-3 |
0.292 |
|
| 2004 |
Ojima I. Use of fluorine in the medicinal chemistry and chemical biology of bioactive compounds--a case study on fluorinated taxane anticancer agents. Chembiochem : a European Journal of Chemical Biology. 5: 628-35. PMID 15122634 DOI: 10.1002/Cbic.200300844 |
0.292 |
|
| 1986 |
Ojima I. Homogeneous mixed-metal catalyst systems: new and effective routes to N-acyl-α-amino acids via carbonylations Journal of Molecular Catalysis. 37: 25-44. DOI: 10.1016/0304-5102(86)85135-5 |
0.292 |
|
| 1981 |
Hatanaka N, Abe R, Ojima I. β-LACTAM AS SYNTHETIC INTERMEDIATE: SYNTHESIS OF LEUCINE-ENKEPHALIN Chemistry Letters. 10: 1297-1298. DOI: 10.1246/Cl.1981.1297 |
0.291 |
|
| 2017 |
Alford VM, Kamath A, Ren X, Kumar K, Gan Q, Awwa M, Tong M, Seeliger MA, Cao J, Ojima I, Sampson NS. Targeting the Hemopexin-like Domain of Latent Matrix Metalloproteinase-9 (proMMP-9) with a Small Molecule Inhibitor Prevents the Formation of Focal Adhesion Junctions. Acs Chemical Biology. PMID 28945333 DOI: 10.1021/Acschembio.7B00758 |
0.289 |
|
| 1994 |
Ojima I, Tzamarioudaki M, Tsai C. Extremely Chemoselective Silylformylation and Silylcarbocyclization of Alkynals Journal of the American Chemical Society. 116: 3643-3644. DOI: 10.1021/Ja00087A078 |
0.289 |
|
| 1995 |
Ojima I, Duclos O, Dormán G, Simonot B, Prestwich GD, Rao S, Lerro KA, Horwitz SB. A new paclitaxel photoaffinity analog with a 3-(4-benzoylphenyl)propanoyl probe for characterization of drug-binding sites on tubulin and P-glycoprotein. Journal of Medicinal Chemistry. 38: 3891-4. PMID 7562921 DOI: 10.1021/Jm00020A001 |
0.288 |
|
| 1997 |
Ojima I, Delaloge F. Asymmetric synthesis of building-blocks for peptides and peptidomimetics by means of the β-lactam synthon method Chem. Soc. Rev.. 26: 377-386. DOI: 10.1039/Cs9972600377 |
0.288 |
|
| 1975 |
Ojima I, Kogure T, Nagai Y. SELECTIVE ASYMMETRIC REDUCTION OF α,β-UNSATURATED KETONES VIA HYDROSILYLATION CATALYZED BY RHODIUM(I) COMPLEXES WITH CHIRAL PHOSPHINE LIGANDS Chemistry Letters. 4: 985-988. DOI: 10.1002/Chin.197606105 |
0.288 |
|
| 1975 |
OJIMA I, INABA S, NAGAI Y. ChemInform Abstract: A FACILE SYNTHESIS OF N-(P-TOLUENESULFONYL)-2-OXOALKANECARBONAMIDES BY THE REACTION OF SILYL ENOL ETHERS WITH P-TOLUENESULFONYL ISOCYANATE Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197543224 |
0.287 |
|
| 1978 |
ACHIWA K, KOGURE T, OJIMA I. ChemInform Abstract: ASYMMETRIC REACTIONS CATALYZED BY TRANSITION METAL COMPLEXES. VI. CATALYTIC ASYMMETRIC SYNTHESES OF R(-)- AND S(+)-PANTOLACTONE Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197807194 |
0.286 |
|
| 1981 |
Hatanaka N, Ojima I. Effective method for the asymmetric synthesis of bis-β-lactams by the cycloaddition of azidoketen to benzylideneamines bearing a chiral β-lactam backbone Journal of the Chemical Society, Chemical Communications. 344-346. DOI: 10.1039/C39810000344 |
0.286 |
|
| 1973 |
Ojima I, Kogure T, Nagai Y. ASYMMETRIC REDUCTION OF KETONES VIA HYDROSILYLATION CATALYZED BY A RHODIUM(I) COMPLEX WITH CHIRAL PHOSPHINE LIGANDS Chemistry Letters. 2: 541-544. DOI: 10.1246/Cl.1973.541 |
0.285 |
|
| 1977 |
Ojima I, Miyazawa Y, Kumagai M. Asymmetric Addition Of Allyltrimethylsilane To (-)-Menthyl Pyruvate And Phenylglyoxylate Cheminform. 8. DOI: 10.1002/Chin.197712089 |
0.285 |
|
| 1991 |
Ojima I, Clos N, Donovan RJ, Ingallina P. Reactions of Co2Rh2(CO)12 with isocyanides and 1-alkynes. Characterization of new isocyanide and 1-alkyne complexes of Co-Rh mixed-metal systems and the structures of [Rh(C.tplbond.N-C6H3Me2-2,6)4][Co(CO)4] and Co2Rh2(CO)7(.mu.-CO)2(.mu.4,.eta.2-HC.tplbond.CBun)(PPh3) Organometallics. 10: 3211-3219. DOI: 10.1021/Om00055A044 |
0.285 |
|
| 2014 |
Knudson SE, Awasthi D, Kumar K, Carreau A, Goullieux L, Lagrange S, Vermet H, Ojima I, Slayden RA. A trisubstituted benzimidazole cell division inhibitor with efficacy against Mycobacterium tuberculosis. Plos One. 9: e93953. PMID 24736743 DOI: 10.1371/Journal.Pone.0093953 |
0.285 |
|
| 1984 |
Fuchikami T, Yamanouchi A, Ojima I. An Effective and Convenient Route to 5-Trifluoromethyl-5,6-dihydrouracils and their Thio Derivatives Synthesis. 1984: 766-768. DOI: 10.1055/S-1984-30964 |
0.284 |
|
| 1999 |
Ojima I, Bounaud PY, Ahern DG. New photoaffinity analogs of paclitaxel Bioorganic and Medicinal Chemistry Letters. 9: 1189-1194. PMID 10328311 DOI: 10.1016/S0960-894X(99)00161-4 |
0.283 |
|
| 1979 |
Ojima I, Kogure T. 31P NMR STUDIES ON THE MECHANISM OF ASYMMETRIC HYDROGENATION CATALYZED BY RHODIUM(I) COMPLEXES WITH CHIRAL PYRROLIDINODIPHOSPHINE LIGAND. EVIDENCE FOR EXTREMELY REGIOSELECTIVE COMPLEXATION OF PROCHIRAL SUBSTRATES Chemistry Letters. 8: 641-644. DOI: 10.1246/Cl.1979.641 |
0.283 |
|
| 2001 |
Bonafoux D, Ojima I. Novel DMAP-catalyzed skeletal rearrangement of 5-exo-(2-hydroxyethylene)oxasilacyclopentanes Organic Letters. 3: 2333-2335. DOI: 10.1021/Ol016153O |
0.283 |
|
| 2003 |
Ojima I, Fumero-Oderda CL, Kuduk SD, Ma Z, Kirikae F, Kirikae T. Structure-activity relationship study of taxoids for their ability to activate murine macrophages as well as inhibit the growth of macrophage-like cells. Bioorganic & Medicinal Chemistry. 11: 2867-88. PMID 12788358 DOI: 10.1016/S0968-0896(03)00181-0 |
0.282 |
|
| 2019 |
Zhou Y, Elmes MW, Sweeney J, Joseph O, Che J, Hsu HC, Li H, Deutsch DG, Ojima I, Kaczocha M, Rizzo RC. Identification of Fatty Acid Binding Protein 5 Inhibitors Through Similarity-based Screening. Biochemistry. PMID 31539229 DOI: 10.1021/Acs.Biochem.9B00625 |
0.282 |
|
| 1983 |
Fuchikami T, Ohishi K, Ojima I. Regioselective hydroesterification and hydrocarboxylation of 3,3,3-trifluoropropene and pentafluorostyrene catalyzed by phosphine-palladium complex The Journal of Organic Chemistry. 48: 3803-3807. DOI: 10.1002/Chin.198411142 |
0.282 |
|
| 1989 |
Ojima I, Kato K, Nakahashi K, Fuchikami T, Fujita M. New and effective routes to fluoro analogs of aliphatic and aromatic amino acids The Journal of Organic Chemistry. 54: 4511-4522. DOI: 10.1021/Jo00280A014 |
0.282 |
|
| 1972 |
Ojima I, Nihonyanagi M, Nagai Y. Rhodium complex catalysed hydrosilylation of carbonyl compounds Journal of the Chemical Society, Chemical Communications. DOI: 10.1039/C3972000938A |
0.281 |
|
| 1975 |
Ojima I, Inaba S, Nagai Y. Reaction Of Trimethylsilyl Cyanide With Isocyanates Cheminform. 6. DOI: 10.1002/Chin.197504258 |
0.28 |
|
| 1973 |
Ojima I, Kondo K. Chemical Evidence for the Existence of pπ-dπ Interaction between the Unsaturated Bond and the Sulfur Atom in Allyl and Vinyl Sulfide Systems Bulletin of the Chemical Society of Japan. 46: 2571-2574. DOI: 10.1246/Bcsj.46.2571 |
0.28 |
|
| 1994 |
Ojima I, Tsai C, Zhang Z. Catalytic asymmetric synthesis of peptides on polymer support Tetrahedron Letters. 35: 5785-5788. DOI: 10.1016/S0040-4039(00)78184-6 |
0.28 |
|
| 1991 |
Ojima I, Ingallina P, Donovan RJ, Clos N. Silylformylation of 1-hexyne catalyzed by rhodium-cobalt mixed-metal carbonyl clusters Organometallics. 10: 38-41. DOI: 10.1021/Om00047A021 |
0.28 |
|
| 1969 |
Ojima I, Akiba K, Inamoto N. Reactions of Diarylphosphines, Their Oxides and Sulfides with Isothiocyanates and Thiocyanic Acid Bulletin of the Chemical Society of Japan. 42: 2975-2981. DOI: 10.1246/Bcsj.42.2975 |
0.28 |
|
| 1988 |
Ojima I, Chen HC, Qiu X. New approaches to the asymmetric synthesis of non-proteinogenic α-amino acids and dipeptides through chiral β-lactam intermediates Tetrahedron. 44: 5307-5318. DOI: 10.1016/S0040-4020(01)86038-5 |
0.28 |
|
| 1996 |
Ojima I, Kuduk SD, Slater JC, Gimi RH, Sun CM. Syntheses of new fluorine-containing taxoids by means of β-Lactam Synthon Method Tetrahedron. 52: 209-224. DOI: 10.1016/0040-4020(95)00865-6 |
0.279 |
|
| 1979 |
Ojima I, Kogure T, Terasaki T, Achiwa K. Effective biomimetic route to D-(+)-pantothenate using asymmetric hydrogenation catalyzed by a chiral rhodium complex in the key step Cheminform. 10. DOI: 10.1002/Chin.197906319 |
0.279 |
|
| 1978 |
Ojima I, Kogure T, Terasaki T, Achiwa K. Effective biomimetic route to D-(+)-pantothenate using asymmetric hydrogenation catalyzed by a chiral rhodium complex in the key step The Journal of Organic Chemistry. 43: 3444-3446. DOI: 10.1021/Jo00412A003 |
0.279 |
|
| 2001 |
Gruol DJ, Bernd J, Phippard AE, Ojima I, Bernacki RJ. The use of a novel taxane-based P-glycoprotein inhibitor to identify mutations that alter the interaction of the protein with paclitaxel Molecular Pharmacology. 60: 104-113. PMID 11408605 DOI: 10.1124/Mol.60.1.104 |
0.279 |
|
| 1978 |
Ojima I, Kumagai M. CHEMOSELECTIVE REACTIONS OF ALLYLSILANES WITH 1,1-DIMETHOXYBUTAN-3-ONE AND 1,1-DIMETHOXYPROPAN-2-ONE Chemistry Letters. 7: 575-578. DOI: 10.1002/Chin.197846170 |
0.278 |
|
| 1982 |
Ojima I, Yatabe M, Fuchikami T. Diels-Alder reactions of (trifluoromethyl)ethene and (trifluoromethyl)styrenes with functionalized butadienes The Journal of Organic Chemistry. 47: 2051-2055. DOI: 10.1021/Jo00132A015 |
0.278 |
|
| 1972 |
Ojima I, Kogure T, Nihonyanagi M, Nagai Y. Reduction of Carbonyl Compounds with Various Hydrosilane-Rhodium(I) Complex Combinations Bulletin of the Chemical Society of Japan. 45: 3506-3506. DOI: 10.1246/Bcsj.45.3506 |
0.278 |
|
| 2017 |
Zong Y, Shea C, Maffucci K, Ojima I. Computational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1. Journal of Fluorine Chemistry. 203: 193-199. PMID 29311752 DOI: 10.1016/J.Jfluchem.2017.09.007 |
0.277 |
|
| 1972 |
OJIMA I, NIHONYANAGI M, NAGAI Y. ChemInform Abstract: DURCH RHODIUM-KOMPLEXE KATALYSIERTE HYDROSILYLIERUNG VON CARBONYL-VERBINDUNGEN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197250301 |
0.277 |
|
| 1982 |
Ojima I, Kogure T, Yoda N, Suzuki T, Yatabe M, Tanaka T. Synthesis of chiral dipeptides by means of asymmetric hydrogenation of dehydro dipeptides The Journal of Organic Chemistry. 47: 1329-1334. DOI: 10.1021/Jo00346A033 |
0.276 |
|
| 1988 |
Ojima I, Chen HJC, Nakahashi K. Asymmetric synthesis with chiral .beta.-lactams. .alpha.-Substituted aromatic .alpha.-amino acids and their derivatives through highly stereoselective alkylations Journal of the American Chemical Society. 110: 278-281. DOI: 10.1021/Ja00209A044 |
0.276 |
|
| 1985 |
Ojima I. Asymmetric Synthesis. Volume 4. The Chiral Carbon Pool and Chiral Sulfur, Nitrogen, Phosphorus, and Silicon Centers Organometallics. 4: 960-960. DOI: 10.1021/Om00124A605 |
0.276 |
|
| 1980 |
Ojima I, Kogure T, Yoda N. Asymmetric hydrogenation of prochiral olefins catalyzed by rhodium complexes with chiral pyrrolidinodiphosphines. Crucial factors for the effective asymmetric induction The Journal of Organic Chemistry. 45: 4728-4739. DOI: 10.1021/Jo01311A036 |
0.276 |
|
| 1995 |
Ojima I, Dong Q, Chakravarty S, Peerschke E, Hwang SM, Wong AS. Design, synthesis and SAR of RGD peptide hybrids as highly efficient inhibitors of platelet aggregation Bioorganic and Medicinal Chemistry Letters. 5: 1941-1946. DOI: 10.1016/0960-894X(95)00329-R |
0.275 |
|
| 1981 |
Fuchikami T, Yatabe M, Ojima I. A Facile Synthesis oftrans-β-Trifluoromethylstyrene,trans-2,3,4,5,6-Pentafluorostilbene and their Derivatives Synthesis. 1981: 365-366. DOI: 10.1055/S-1981-29449 |
0.275 |
|
| 1983 |
Fujita M, Ojima I. Selenium dioxide oxidation of 3-methyl-4,5,6,7-tetrafluoroindoles: an efficient route to tetrafluoro analogs of 3-formyl and 3-acetoxymethylindole systems Tetrahedron Letters. 24: 4573-4576. DOI: 10.1016/S0040-4039(00)85959-6 |
0.275 |
|
| 1982 |
Ojima I, Yoda N. Synthesis of chiral tripeptides by asymmetric hydrogenation of dehydrotripeptides. Remarkable effects of N-protecting groups on stereoselectivity and reactivity Tetrahedron Letters. 23: 3913-3916. DOI: 10.1016/S0040-4039(00)87741-2 |
0.275 |
|
| 1972 |
Ojima I, Nihonyanagi M, Nagai Y. Stereoselective Reduction of Ketones with Hydrosilane-Rhodium(I) Complex Combinations Bulletin of the Chemical Society of Japan. 45: 3722-3722. DOI: 10.1246/Bcsj.45.3722 |
0.274 |
|
| 1978 |
Achiwa K, Kogure T, Ojima I. HIGHLY EFFECTIVE CATALYTIC ASYMMETRIC SYNTHESIS OF R-(−)-PANTOLACTONE Chemistry Letters. 7: 297-298. DOI: 10.1246/Cl.1978.297 |
0.274 |
|
| 1998 |
Ojima I, Zhaoyang L, Donovan RJ, Ingallina P. On the mechanism of silylformylation catalyzed by Rh-Co mixed metal complexes Inorganica Chimica Acta. 270: 279-284. DOI: 10.1016/S0020-1693(97)05855-6 |
0.274 |
|
| 1992 |
Ojima I, Brandstadter SM, Donovan RJ. Oxidative Dimerization of Lithium-Enolates of Esters Promoted by TitaniumTetrachloride Chemistry Letters. 21: 1591-1594. DOI: 10.1246/Cl.1992.1591 |
0.273 |
|
| 1976 |
Ojima I, Kumagai M, Nagai Y. Hydrosilylation of α,β-unsaturated nitriles and esters catalyzed by tris (triphenylphosphine)chlororhodium Journal of Organometallic Chemistry. 111: 43-60. DOI: 10.1016/S0022-328X(00)87057-6 |
0.273 |
|
| 2016 |
Zhou Y, McGillick BE, Teng YG, Haranahalli K, Ojima I, Swaminathan S, Rizzo RC. Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity. Bioorganic & Medicinal Chemistry. PMID 27543389 DOI: 10.1016/J.Bmc.2016.07.031 |
0.273 |
|
| 1973 |
Ojima I, Nihonyanagi M, Nagai Y. A novel route to silylthioethers Journal of Organometallic Chemistry. 50: C26-C28. DOI: 10.1016/S0022-328X(00)95067-8 |
0.273 |
|
| 2006 |
Yoshikai N, Yamanaka M, Ojima I, Morokuma K, Nakamura E. Bimetallic synergism in alkyne silylformylation catalyzed by a cobalt - Rhodium mixed-metal cluster Organometallics. 25: 3867-3875. DOI: 10.1021/Om060478X |
0.273 |
|
| 2013 |
Ojima I. Exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology. The Journal of Organic Chemistry. 78: 6358-83. PMID 23614876 DOI: 10.1021/Jo400301U |
0.272 |
|
| 1972 |
Kondo K, Ojima I. Intramolecular reactions of α- and β-allylthioalkylcarbenes Journal of the Chemical Society, Chemical Communications. 62-63. DOI: 10.1039/C39720000062 |
0.272 |
|
| 2021 |
Wang C, Chen L, Sun Y, Guo W, Taouil AK, Ojima I. Design, synthesis and SAR study of Fluorine-containing 3rd-generation taxoids. Bioorganic Chemistry. 119: 105578. PMID 34979464 DOI: 10.1016/j.bioorg.2021.105578 |
0.271 |
|
| 1978 |
Ojima I, Kogure T. 31P NMR STUDIES ON THE MECHANISM OF ASYMMETRIC HYDROGENATION CATALYZED BY RHODIUM(I) COMPLEXES WITH CHIRAL PYRROLIDINODIPHOSPHINE LIGAND Chemistry Letters. 7: 1145-1148. DOI: 10.1246/Cl.1978.1145 |
0.271 |
|
| 1987 |
Ojima I, Qiu X. Asymmetric alkylation of chiral .beta.-lactam ester enolates. A new approach to the synthesis of .alpha.-alkylated .alpha.-amino acids Journal of the American Chemical Society. 109: 6537-6538. DOI: 10.1021/Ja00255A063 |
0.271 |
|
| 1981 |
Ojima I, Tanaka T, Kogure T. SYNTHESIS OF CHIRAL DEPSIPEPTIDE BUILDING BLOCK BY THE ASYMMETRIC REDUCTION OFN-(α-KETOACYL)-α-AMINO ESTERS Chemistry Letters. 10: 823-826. DOI: 10.1002/Chin.198149338 |
0.27 |
|
| 1992 |
Ojima I, Donovan RJ, Ingallina P, Clos N, Shay WR, Eguchi M, Zeng Q, Korda A. Organometallic chemistry and homogeneous catalysis of Rh and Rh-Co mixed metal carbonyl clusters Journal of Cluster Science. 3: 423-438. DOI: 10.1007/Bf00702749 |
0.27 |
|
| 2014 |
Zheng S, Huang JT, Knatko EV, Sharp S, Higgins M, Ojima I, Dinkova-Kostova AT, Honda T. Synthesis of (13) C2 (15) N2 -labeled anti-inflammatory and cytoprotective tricyclic bis(cyanoenone) ([(13) C2 (15) N2 ]-TBE-31) as an internal standard for quantification by stable isotope dilution LC-MS method. Journal of Labelled Compounds & Radiopharmaceuticals. 57: 606-10. PMID 25196444 DOI: 10.1002/Jlcr.3230 |
0.27 |
|
| 1984 |
Ojima I, Noriko Yoda T, Yatabe M, Tanaka T, Kogure T. Synthesis of chiral oligopeptides by means of catalytic asymmetric hydrogenation of dehydropeptides Tetrahedron. 40: 1255-1268. DOI: 10.1016/S0040-4020(01)82412-1 |
0.27 |
|
| 1982 |
Hatanaka N, Abe R, Ojima I. SYNTHESIS OF OPTICALLY PURE ENKEPHALIN ANALOG, [D-Ala2, Leu5-ol]ENKEPHALIN, USING CHIRAL β-LACTAMS AS SYNTHETIC INTERMEDIATES Chemistry Letters. 11: 445-448. DOI: 10.1002/Chin.198245342 |
0.269 |
|
| 1996 |
Ojima I, Chakravarty S, Dong Q. Antithrombotic agents: from RGD to peptide mimetics. Bioorganic & Medicinal Chemistry. 3: 337-60. PMID 8581417 DOI: 10.1016/0968-0896(95)00036-G |
0.269 |
|
| 2012 |
Ojima I, Hirai K. Asymmetric Hydrosilylation and Hydrocarbonylation Asymmetric Synthesis. 103-146. DOI: 10.1002/Chin.198634368 |
0.269 |
|
| 1982 |
Hirai K, Takahashi Y, Ojima I. Direct conversion of allylic alcohols into N-acyl-α-amino acids by catalytic amidocarbonylation by means of homogeneous binary systems Tetrahedron Letters. 23: 2491-2494. DOI: 10.1016/S0040-4039(00)87377-3 |
0.269 |
|
| 1979 |
Ojima I, Inaba S. A convenient synthesis of 1,3-dimethyl(5h,7h)imidazo(4,5-dpyrimidine-2,4,6-trithione and its unusual character Tetrahedron Letters. 20: 817-820. DOI: 10.1016/S0040-4039(01)86047-0 |
0.268 |
|
| 1996 |
Hayashi Y, Sato Y, Katada J, Takiguchi Y, Ojima I, Uno I. Design and synthesis of new antagonist peptides for platelet GPIIb/IIIa receptor as anti-thrombotic agents Bioorganic & Medicinal Chemistry Letters. 6: 1351-1356. DOI: 10.1016/0960-894X(96)00224-7 |
0.268 |
|
| 1993 |
Ojima I, Zucco M, Duclos O, Kuduk SD, Sun CM, Park YH. N-acyl-3-hydroxy-β-lactams as key intermediates for taxotere and its analogs Bioorganic & Medicinal Chemistry Letters. 3: 2479-2482. DOI: 10.1016/S0960-894X(01)80982-3 |
0.268 |
|
| 1999 |
Glunz PW, He L, Horwitz SB, Chakravarty S, Ojima I, Chou TC, Danishefsky SJ. The synthesis and evaluation of 12,13-benzodesoxyepothilone B: A highly convergent route Tetrahedron Letters. 40: 6895-6898. DOI: 10.1016/S0040-4039(99)01433-1 |
0.267 |
|
| 2005 |
Yang CP, Verdier-Pinard P, Wang F, Lippaine-Horvath E, He L, Li D, Höfle G, Ojima I, Orr GA, Horwitz SB. A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence. Molecular Cancer Therapeutics. 4: 987-95. PMID 15956256 DOI: 10.1158/1535-7163.Mct-05-0024 |
0.267 |
|
| 1974 |
OJIMA I. Journal of Synthetic Organic Chemistry, Japan. 32: 687-703. DOI: 10.5059/Yukigoseikyokaishi.32.687 |
0.266 |
|
| 1970 |
Ojima I, Inamoto N. 1,2-Cycloaddition of phosphinothioyl and sulphonyl isothiocyanates with carbodi-imides Journal of the Chemical Society D: Chemical Communications. 1629-1629. DOI: 10.1039/C29700001629 |
0.266 |
|
| 1997 |
Ojima I, Kuduk SD, Chakravarty S, Ourevitch M, Bégué J. A Novel Approach to the Study of Solution Structures and Dynamic Behavior of Paclitaxel and Docetaxel Using Fluorine-Containing Analogs as Probes Journal of the American Chemical Society. 119: 5519-5527. DOI: 10.1021/Ja9633777 |
0.266 |
|
| 1998 |
Wu Q, Bounaud PY, Kuduk SD, Yang CP, Ojima I, Horwitz SB, Orr GA. Identification of the domains of photoincorporation of the 3'- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein. Biochemistry. 37: 11272-9. PMID 9698374 DOI: 10.1021/Bi980598B |
0.266 |
|
| 1970 |
EMOTO T, OKAZAKI R, OJIMA I, OCHIAI T, KAWASHIMA T, NAKAYAMA J, NAKAYAMA S, YAMADA K, YOSHIFUJI M. Tables for Syntheses of Organophosphorus Compounds Journal of Synthetic Organic Chemistry, Japan. 28: 143-176. DOI: 10.5059/Yukigoseikyokaishi.28.143 |
0.265 |
|
| 1982 |
Ojima I, Kogure T. Reduction of carbonyl compounds via hydrosilylation. 4. Highly regioselective reductions of .alpha.,.beta.-unsaturated carbonyl compounds Organometallics. 1: 1390-1399. DOI: 10.1021/Om00070A024 |
0.265 |
|
| 1999 |
Ojima I, Lin S, Wang T. Recent advances in the medicinal chemistry of taxoids with novel β- amino acid side chains Current Medicinal Chemistry. 6: 927-954. PMID 10519906 |
0.264 |
|
| 1987 |
Ojima I, Chen HC. Novel and effective routes to optically pure amino acids, dipeptides, and their derivatives viaβ-lactams obtained through asymmetric cycloaddition Journal of the Chemical Society, Chemical Communications. 625-626. DOI: 10.1039/C39870000625 |
0.264 |
|
| 1989 |
Ojima I, Clos N, Bastos C. Recent advances in catalytic asymmetric reactions promoted by transition metal complexes Tetrahedron. 45: 6901-6939. DOI: 10.1016/S0040-4020(01)89159-6 |
0.264 |
|
| 1988 |
Ojima I, Kwon HB. Remarkable effects of a pentafluorophenyl group on the stereoselective reactions of a chiral iron acyl complex Journal of the American Chemical Society. 110: 5617-5621. DOI: 10.1021/Ja00225A004 |
0.264 |
|
| 1979 |
Ojima I, Kogure T, Yoda N. ASYMMETRIC HYDROGENATION OF α-ACYLAMINOCINNAMIC ACID CATALYZED BY CHIRAL RHODIUM COMPLEXES. REMARKABLE EFFECTS OF HYDROGEN PRESSURE ON STEREOSELECTIVITY Chemistry Letters. 8: 495-498. DOI: 10.1246/Cl.1979.495 |
0.263 |
|
| 1994 |
OJIMA I, DONG Q, CHAKRAVARTY S. Platelet Aggregation Inhibitory Agents: From RGD to Peptide Mimetics. Journal of Synthetic Organic Chemistry, Japan. 52: 413-425. DOI: 10.5059/Yukigoseikyokaishi.52.413 |
0.263 |
|
| 2019 |
Oliverius M, Flasarova D, Mohelnikova-Duchonova B, Ehrlichova M, Hlavac, Kocik M, Strouhal O, Dvorak P, Ojima I, Soucek P. KRAS pathway expression changes in pancreatic cancer models by conventional and experimental taxanes Mutagenesis. 34: 403-411. PMID 31375828 DOI: 10.1093/Mutage/Gez021 |
0.262 |
|
| 1976 |
Ojima I, Kogure T, Kumagai M, Horiuchi S, Sato T. Reduction of carbonyl compounds via hydrosilylation Journal of Organometallic Chemistry. 122: 83-97. DOI: 10.1016/S0022-328X(00)86954-5 |
0.262 |
|
| 1975 |
Ojima I, Inaba S, Nakatsugawa K, Nagai Y. A NEW ROUTE TO AMINONITRILES VIA CYANOSILYLATION OF SCHIFF BASES AND OXIMES Chemistry Letters. 4: 331-334. DOI: 10.1002/Chin.197545212 |
0.262 |
|
| 2019 |
Kim J, Bogdan DM, Elmes MW, Awwa M, Yan S, Che J, Lee G, Deutsch DG, Rizzo RC, Kaczocha M, Ojima I. Incarvillateine produces antinociceptive and motor suppressive effects via adenosine receptor activation. Plos One. 14: e0218619. PMID 31237895 DOI: 10.1371/Journal.Pone.0218619 |
0.262 |
|
| 2013 |
Jelínek M, Balušíková K, Kopperová D, Nĕmcová-Fürstová V, Šrámek J, Fidlerová J, Zanardi I, Ojima I, Kovář J. Caspase-2 is involved in cell death induction by taxanes in breast cancer cells. Cancer Cell International. 13: 42. PMID 23672670 DOI: 10.1186/1475-2867-13-42 |
0.262 |
|
| 1974 |
Ojima I, Inaba S, Nagai Y. Syntheses of N-silylformamidines by the hydrosilylation of carbodiimides Journal of Organometallic Chemistry. 72: C11-C13. DOI: 10.1016/S0022-328X(00)82030-6 |
0.262 |
|
| 1983 |
Yamashita M, Ojima I. Effective route to azetidines from azetidin-2-ones with the use of hydroalanes as specific reducing agents Cheminform. 15: 6339-6342. DOI: 10.1021/Ja00358A040 |
0.261 |
|
| 1986 |
OJIMA I. Asymmetric synthesis by means of chiral metal complex catalysts. Journal of Synthetic Organic Chemistry, Japan. 44: 499-512. DOI: 10.1002/Chin.198651362 |
0.26 |
|
| 1975 |
Ojima I. Recent Progress In The Catalytic Asymmetric Reductions Using Homogeneous Catalysts With Chiral Ligands Cheminform. 6. DOI: 10.1002/Chin.197511165 |
0.26 |
|
| 1998 |
Kirikae T, Ojima I, Ma Z, Kirikae F, Hirai Y, Nakano M. Structural significance of the benzoyl group at the C-3'-N position of paclitaxel for nitric oxide and tumor necrosis factor production by murine macrophages. Biochemical and Biophysical Research Communications. 245: 698-704. PMID 9588177 DOI: 10.1006/Bbrc.1998.8409 |
0.259 |
|
| 1969 |
Ojima I, Iwamoto T, Onishi T, Inamoto N, Tamaru K. A novel series of transition-metal chelates of diphenylphosphinothioylthiourea anion Journal of the Chemical Society D: Chemical Communications. 1501-1502. DOI: 10.1039/C29690001501 |
0.259 |
|
| 1975 |
Ojima I, Inaba S, Nagai Y. ASYMMETRIC SYNTHESES OF α-AMINONITRILES VIA CYANOSILYLATION OF SCHIFF BASES Chemistry Letters. 4: 737-740. DOI: 10.1002/Chin.197601180 |
0.259 |
|
| 2009 |
Ojima I. Bioorganic and Medicinal Chemistry of Fluorine. By Jean-Pierre Bégué and Danièle Bonnet-Delpon. Chembiochem. 10: 377-377. DOI: 10.1002/Cbic.200800794 |
0.256 |
|
| 2015 |
Jelínek M, Balušíková K, Schmiedlová M, Němcová-Fürstová V, Šrámek J, Stančíková J, Zanardi I, Ojima I, Kovář J. The role of individual caspases in cell death induction by taxanes in breast cancer cells. Cancer Cell International. 15: 8. PMID 25685064 DOI: 10.1186/S12935-015-0155-7 |
0.255 |
|
| 1988 |
Ojima I, Zhang Z. Novel amide-directed hydrocarbonylations and double carbonylation of N-allylamides The Journal of Organic Chemistry. 53: 4422-4425. DOI: 10.1021/Jo00253A051 |
0.255 |
|
| 1994 |
Ojima I, Park YH, Sun CM, Fenoglio I, Appendino G, Pera P, Bernacki RJ. Structure-activity relationships of new taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III. Journal of Medicinal Chemistry. 37: 1408-10. PMID 8182698 DOI: 10.1021/Jm00036A004 |
0.255 |
|
| 2003 |
Ojima I, Kogure T, Yoda Y. Asymmetric Hydrogenation of Ketopantoyl Lactone: D‐(−)‐Pantoyl Lactone Organic Syntheses. 18-18. DOI: 10.1002/0471264180.Os063.03 |
0.254 |
|
| 1996 |
Kirikae T, Ojima I, Kirikae F, Ma Z, Kuduk SD, Slater JC, Takeuchi CS, Bounaud PY, Nakano M. Structural requirements of taxoids for nitric oxide and tumor necrosis factor production by murine macrophages. Biochemical and Biophysical Research Communications. 227: 227-35. PMID 8858130 DOI: 10.1006/Bbrc.1996.1494 |
0.254 |
|
| 2017 |
Hsu HC, Tong S, Zhou Y, Elmes MW, Yan S, Kaczocha M, Deutsch DG, Rizzo RC, Ojima I, Li H. The antinociceptive agent SBFI-26 binds to anandamide transporters FABP5 and FABP7 at two different sites. Biochemistry. PMID 28632393 DOI: 10.1021/Acs.Biochem.7B00194 |
0.254 |
|
| 1997 |
Asari T, Ishikawa S, Sasaki T, Katada J, Hayashi Y, Harada T, Yano M, Yasuda E, Uno I, Ojima I. Development of new non-peptide GPIIb/IIIa antagonists, NSL-95315 and NSL-95317, isosteres of NSL-95300 Bioorganic & Medicinal Chemistry Letters. 7: 2099-2104. DOI: 10.1016/S0960-894X(97)00366-1 |
0.253 |
|
| 2014 |
Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H. Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. Acta Crystallographica. Section D, Biological Crystallography. 70: 290-8. PMID 24531463 DOI: 10.1107/S1399004713026795 |
0.253 |
|
| 1993 |
Eguchi M, Zeng Q, Korda A, Ojima I. Synthesis of pyrrolizidine alkaloids via rhodium-catalyzed silylformylation and amidocarbonylation Tetrahedron Letters. 34: 915-918. DOI: 10.1016/S0040-4039(00)77453-3 |
0.252 |
|
| 1973 |
Ojima I, Kogure T, Nagai Y. A novel method for the reduction of schiff bases using catalytic hydrosilylation Tetrahedron Letters. 14: 2475-2478. DOI: 10.1016/S0040-4039(01)96182-9 |
0.251 |
|
| 1991 |
Ojima I, Zhao M, Yamato T, Nakahashi K, Yamashita M, Abe R. Azetidines and bisazetidines. Their synthesis and use as the key intermediates to enantiomerically pure diamines, amino alcohols, and polyamines Journal of Organic Chemistry. 56: 5263-5277. DOI: 10.1021/Jo00018A012 |
0.25 |
|
| 2011 |
Chien C-, Shi C, Lin C-, Ojima I. Pd-Catalyzed Intramolecular Asymmetric Allylic Amination Synfacts. 2011: 1339-1339. DOI: 10.1055/S-0031-1289330 |
0.25 |
|
| 1999 |
Rao S, He L, Chakravarty S, Ojima I, Orr GA, Horwitz SB. Characterization of the Taxol binding site on the microtubule. Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol. The Journal of Biological Chemistry. 274: 37990-4. PMID 10608867 DOI: 10.1074/Jbc.274.53.37990 |
0.25 |
|
| 1973 |
Kono H, Ojima I, Matsumoto M, Nagai Y. A CONVENIENT ROUTE TO AMINOSILANES USING HYDROSILANE-RHODIUM(I) COMPLEX COMBINATIONS Organic Preparations and Procedures International. 5: 135-139. DOI: 10.1080/00304947309355562 |
0.249 |
|
| 2014 |
Singh D, Bhattacharya A, Rai A, Dhaked HP, Awasthi D, Ojima I, Panda D. SB-RA-2001 inhibits bacterial proliferation by targeting FtsZ assembly. Biochemistry. 53: 2979-92. PMID 24749867 DOI: 10.1021/Bi401356Y |
0.249 |
|
| 1986 |
Ojima I, Shimizu N. Extremely stereoselective and stereospecific reductive cleavage of .beta.-lactams. A highly efficient route to labeled homochiral peptides Journal of the American Chemical Society. 108: 3100-3102. DOI: 10.1021/Ja00271A048 |
0.249 |
|
| 2001 |
Bonafoux D, Ojima I. Desymmetrization of 4-dimethylsiloxy-1,6-heptadiynes through sequential double silylformylation Organic Letters. 3: 1303-1304. DOI: 10.1021/Ol0156594 |
0.248 |
|
| 1981 |
Hatanaka N, Ojima I. β-LACTAM AS SYNTHETIC INTERMEDIATE. A NEW SYNTHETIC APPROACH TO OLIGOPEPTIDES THROUGH NOVEL β-LACTAMS Cheminform. 12. DOI: 10.1002/Chin.198135328 |
0.248 |
|
| 1997 |
Harada T, Katada J, Tachiki A, Asari T, Iijima K, Uno I, Ojima I, Hayashi Y. Development of the new potent non-peptide gpIIb/IIIa antagonist NSL-95301 by utilizing combinatorial technique Bioorganic & Medicinal Chemistry Letters. 7: 209-212. DOI: 10.1016/S0960-894X(96)00610-5 |
0.248 |
|
| 1974 |
Ojima I, Kumagai M, Nagai Y. α-Silylpropionitriles: A new reagent for the synthesis of α,β-unsaturated nitriles Tetrahedron Letters. 15: 4005-4008. DOI: 10.1016/S0040-4039(01)92069-6 |
0.248 |
|
| 2013 |
Saito A, Higgins M, Zheng S, Li W, Ojima I, Dinkova-Kostova AT, Honda T. Synthesis and biological evaluation of biotin conjugates of (±)-(4bS,8aR,10aS)-10a-ethynyl-4b,8,8-trimethyl-3,7-dioxo-3,4b,7,8,8a,9,10,10a-octahydro-phenanthrene-2,6-dicarbonitrile, an activator of the Keap1/Nrf2/ARE pathway, for the isolation of its protein targets. Bioorganic & Medicinal Chemistry Letters. 23: 5540-3. PMID 24018193 DOI: 10.1016/J.Bmcl.2013.08.058 |
0.247 |
|
| 1982 |
Ojima I, Yoda N, Yatabe M. Synthesis of Enkephalin analogs via asymmetric hydrogenation of dehydropeptide building blocks Tetrahedron Letters. 23: 3917-3920. DOI: 10.1016/S0040-4039(00)87742-4 |
0.246 |
|
| 1990 |
Ojima I, Clos N, Donovan RJ, Ingallina P. Hydrosilylation of 1-hexyne catalyzed by rhodium and cobalt-rhodium mixed-metal complexes. Mechanism of apparent trans addition Organometallics. 9: 3127-3133. DOI: 10.1021/Om00162A026 |
0.244 |
|
| 1981 |
OJIMA I, KOGURE T. ChemInform Abstract: HYDROSILYLATION OF DIENES, ACETYLENES, AND CARBONYLS CATALYZED BY TRANSITION METAL COMPLEXES Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198149361 |
0.243 |
|
| 2024 |
Sun Y, Kim S, Shin S, Takemura K, Matos GS, Lazzarini C, Haranahalli K, Zambito J, Garg A, Del Poeta M, Ojima I. SAR study of N'-(Salicylidene)heteroarenecarbohydrazides as promising antifungal agents. Bioorganic & Medicinal Chemistry. 100: 117610. PMID 38306882 DOI: 10.1016/j.bmc.2024.117610 |
0.243 |
|
| 2012 |
Otová B, Ojima I, Václavíková R, Hrdý J, Ehrlichová M, Sou?ek P, Vobo?ilová J, N?mcová V, Zanardi I, Horský S, Ková? J, Gut I. Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes. Investigational New Drugs. 30: 991-1002. PMID 21448670 DOI: 10.1007/S10637-011-9654-0 |
0.242 |
|
| 1975 |
Kondo K, Ojima I. The Intramolecular Participation Of Sulfide Linkage On The Reactivity Of Carbenes And Diazoalkanes Part 2, Alkylcarbenes And Diazoalkanes Bearing Arylthio And Allylthio Groups On Beta-Carbon Cheminform. 6. DOI: 10.1002/Chin.197532148 |
0.241 |
|
| 1987 |
Ojima I, Nakahashi K, Brandstadter SM, Hatanaka N. Remarkable effects of lone pair-lone pair interactions on the extremely stereoselective [2 + 2] cycloaddition of azidoketene to chiral 3-imino-.beta.-lactams Journal of the American Chemical Society. 109: 1798-1805. DOI: 10.1021/Ja00240A033 |
0.24 |
|
| 2018 |
Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, et al. Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids". Mbio. 9. PMID 29535196 DOI: 10.1128/Mbio.00188-18 |
0.24 |
|
| 1996 |
Ojima I, Tzamarioudaki M, Li Z, Donovan RJ. Transition Metal-Catalyzed Carbocyclizations in Organic Synthesis. Chemical Reviews. 96: 635-662. PMID 11848768 DOI: 10.1021/Cr950065Y |
0.24 |
|
| 1973 |
OJIMA I, NIHONYANAGI M, NAGAI Y. ChemInform Abstract: STEREOSELEKTIVE RED. VON KETONEN MIT HYDROSILAN-RHODIUM(I)-KOMPLEX-KOMBINATIONEN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197310206 |
0.239 |
|
| 2018 |
Bogdan D, Falcone J, Kanjiya MP, Park SH, Carbonetti G, Studholme K, Gomez M, Lu Y, Elmes MW, Smietalo N, Yan S, Ojima I, Puopolo M, Kaczocha M. Fatty acid binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation. The Journal of Biological Chemistry. PMID 29440395 DOI: 10.1074/Jbc.Ra118.001593 |
0.239 |
|
| 1973 |
OJIMA I, KOGURE T, NIHONYANAGI M, NAGAI Y. ChemInform Abstract: RED. VON CARBONYLVERBINDUNGEN MIT VERSCHIEDENEN HYDROSILAN-RHODIUM(I)-KOMPLEX-KOMBINATIONEN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197304156 |
0.239 |
|
| 1988 |
Ojima I. New aspects of carbonylations catalyzed by transition metal complexes Chemical Reviews. 88: 1011-1030. DOI: 10.1021/Cr00089A002 |
0.239 |
|
| 2018 |
Wang T, Zhang Y, Wei L, Teng YG, Honda T, Ojima I. Design, Synthesis, and Biological Evaluations of Asymmetric Bow-Tie PAMAM Dendrimer-Based Conjugates for Tumor-Targeted Drug Delivery. Acs Omega. 3: 3717-3736. PMID 29732446 DOI: 10.1021/acsomega.8b00409 |
0.238 |
|
| 1990 |
Ojima I, Komata T, Qiu X. Asymmetric alkylations of a phenylalanylglycinate equivalent. Novel route to dipeptides bearing .alpha.-alkyl-.alpha.-amino acid residues Journal of the American Chemical Society. 112: 770-774. DOI: 10.1021/Ja00158A041 |
0.238 |
|
| 2017 |
Peng X, Studholme K, Kanjiya MP, Luk J, Bogdan D, Elmes MW, Carbonetti G, Tong S, Gary Teng YH, Rizzo RC, Li H, Deutsch DG, Ojima I, Rebecchi MJ, Puopolo M, et al. Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms. Molecular Pain. 13: 1744806917697007. PMID 28326944 DOI: 10.1177/1744806917697007 |
0.238 |
|
| 1971 |
Ojima I, Onishi T, Iwamoto T, Inamoto N, Tamaru K. Syntheses of a New Series of Transition Metal Chelates of Diphenylphosphinothioylthiourea Anion Bulletin of the Chemical Society of Japan. 44: 2150-2154. DOI: 10.1246/Bcsj.44.2150 |
0.238 |
|
| 2008 |
Duncan R, Ojima I, Neri D, Shimma N, Okabe H, Ishitsuka H, Märki HP. Mini-symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 29, 2008 Chimia. 62: 918-934. DOI: 10.2533/chimia.2008.918 |
0.237 |
|
| 2012 |
Ojima I. Interview with Future Medicinal Chemistry's US Senior Editor, Iwao Ojima. Interview by Issac Bruce. Future Medicinal Chemistry. 4: 2019-22. PMID 23157234 DOI: 10.4155/Fmc.12.151 |
0.236 |
|
| 1987 |
Ojima I, Kato K, Okabe M, Fuchikami T. Hydroformylation of fluoro olefins, RfCH:CH2, catalyzed by group VIII transition-metal catalysts. Crucial factors for extremely high regioselectivity Journal of the American Chemical Society. 109: 7714-7720. DOI: 10.1021/Ja00259A020 |
0.234 |
|
| 2013 |
Saito A, Zheng S, Takahashi M, Li W, Ojima I, Honda T. An improved synthesis of a hydroxymethyl tricyclic ketone from cyclohexanone, the key processes for the synthesis of a highly potent anti-inflammatory and cytoprotective agent Synthesis (Germany). 45: 3251-3254. DOI: 10.1055/S-0033-1339900 |
0.234 |
|
| 1977 |
Achiwa K, Kogure T, Ojima I. Catalytic asymmetric syntheses of R(−)- and S(+)-pantolactone Tetrahedron Letters. 18: 4431-4432. DOI: 10.1016/S0040-4039(01)83528-0 |
0.232 |
|
| 1973 |
Ojima I, Kondo K. Chemical Evidence For The Existence Of P Pi-D Pi Interaction Between The Unsaturated Bond And The Sulfur Atom In Allyl And Vinyl Sulfide Systems Cheminform. 4. DOI: 10.1002/Chin.197344092 |
0.232 |
|
| 1991 |
Ojima I, Jameison FA. A new potent inhibitor for angiotensin converting enzyme: (R,S)-captopril-F3 Bioorganic & Medicinal Chemistry Letters. 1: 581-584. DOI: 10.1016/S0960-894X(01)81155-0 |
0.232 |
|
| 1973 |
Ojima I, Kondi K. Intramolecular Participation Of Sulfide Linkage In The Reactivity Of Carbene And Diazoalkanes Part 1, Alkylcarbenes And Diazoalkanes Bearing Alkylthio, Arylthio, And Allylthio Groups On Alpha-Carbon Cheminform. 4. DOI: 10.1002/Chin.197332154 |
0.232 |
|
| 1975 |
OJIMA I, KUMAGAI M, NAGAI Y. ChemInform Abstract: ALPHA-SILYLPROPIONITRILES, A NEW REAGENT FOR THE SYNTHESIS OF ALPHA,BETA-UNSATURATED NITRILES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197507164 |
0.23 |
|
| 1980 |
OJIMA I. ChemInform Abstract: NEWER METHODS IN SELECTIVE AND ASYMMETRIC REDUCTIONS USING HOMOGENEOUS TRANSITION METAL CATALYSTS Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198051337 |
0.23 |
|
| 2020 |
Fernandes CM, Dasilva D, Haranahalli K, McCarthy JB, Mallamo J, Ojima I, Del Poeta M. The future of antifungal drug therapy: novel compounds and targets. Antimicrobial Agents and Chemotherapy. PMID 33229427 DOI: 10.1128/AAC.01719-20 |
0.229 |
|
| 1975 |
Kono H, Wakao N, Ojima I, Nagai Y. THE FORMATION OF SILYLRHODIUM COMPLEXES BY OXIDATIVE ADDITION OF HYDROSILANES TO HYDRIDOTETRAKIS(TRIPHENYLPHOSPHINE) RHODIUM(I). A HOMOGENEOUS CATALYST FOR HYDROSILATION Chemistry Letters. 4: 189-190. DOI: 10.1002/Chin.197544290 |
0.229 |
|
| 2009 |
Ojima I, Thurston DE. Welcome to Future Medicinal Chemistry Future Medicinal Chemistry. 1: 1-2. DOI: 10.4155/Fmc.09.14 |
0.229 |
|
| 2015 |
Mohelnikova-Duchonova B, Kocik M, Duchonova B, Brynychova V, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Ojima I, Soucek P. Importance of hedgehog signaling pathway in pancreatic cancer treatment and prognosis Pancreatology. 15: S37. DOI: 10.1016/J.Pan.2015.05.159 |
0.228 |
|
| 1988 |
Ojima I, Nakahashi K, Brandstadter SM, Hatanaka N. Remarkable effects of lone pair-lone pair interactions on the extremely stereoselective [2 + 2] cycloaddition of azidoketene to chiral 3-imino-.beta.-lactams [Erratum to document cited in CA106(19):156852x] Journal of the American Chemical Society. 110: 1323-1323. DOI: 10.1021/Ja00212A068 |
0.227 |
|
| 1972 |
Kondo K, Ojima I. Intramolecular cycloadditions of α- and β-allylthioalkyl diazoalkanes Journal of the Chemical Society, Chemical Communications. 63-64. DOI: 10.1039/C39720000063 |
0.227 |
|
| 1994 |
Ojima I, Dong Q, Eguchi M, Oh Y, Amann CM, Coller BS. Structure-activity relationships of double-strand RGD peptides as GPIIb/IIIa receptor antogonists Bioorganic & Medicinal Chemistry Letters. 4: 1749-1754. DOI: 10.1016/S0960-894X(00)80374-1 |
0.224 |
|
| 1988 |
Ojima I, Okabe M, Kato K, Kwon HB, Horvath IT. Homogeneous catalysis of mixed-metal systems. Highly regioselective hydroformylation-amidocarbonylation of a fluoro olefin catalyzed by cobalt-rhodium mixed-metal systems. Observation of CoRh(CO)7 catalysis Journal of the American Chemical Society. 110: 150-157. DOI: 10.1021/Ja00209A024 |
0.224 |
|
| 1972 |
KONDO K, NEGISHI A, OJIMA I. ChemInform Abstract: SAEUREKATALYSIERTE RINGOEFFNUNGSRK. VON EPISULFOXIDEN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197244166 |
0.223 |
|
| 1970 |
EMOTO T, OKAZAKI R, OJIMA I, OCHIAI T, KAWASHIMA T, NAKAYAMA S, YAMADA K, YOSHIFUJI M. ChemInform Abstract: TABELLEN FUER SYNTH. VON PHOSPHORORGANISCHEN VERBINDUNGEN Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197028008 |
0.223 |
|
| 1973 |
Ojima I, Inaba S, Kogure T, Matsumoto M, Matsumoto H, Watanabe H, Nagai Y. Reactions of hydropolysilanes with alcohols catalysed by tris(triphenylphosphine)chlororhodium Journal of Organometallic Chemistry. 55: C4-C6. DOI: 10.1016/S0022-328X(00)84017-6 |
0.223 |
|
| 2018 |
Ahmad G, Gattacecca F, El Sadda R, Botchkina G, Ojima I, Egan J, Amiji M. Biodistribution and Pharmacokinetic Evaluations of a Novel Taxoid DHA-SBT-1214 in an Oil-in-Water Nanoemulsion Formulation in Naïve and Tumor-Bearing Mice. Pharmaceutical Research. 35: 91. PMID 29520477 DOI: 10.1007/S11095-018-2349-X |
0.223 |
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| 1973 |
OJIMA I, NIHONYANAGI M, NAGAI Y. ChemInform Abstract: EIN NEUER WEG ZU SILYLTHIOAETHERN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197324305 |
0.222 |
|
| 1970 |
OJIMA I, ONISHI T, IWAMOTO T, INAMOTO N, TAMARU K. ChemInform Abstract: NEUER WEG ZU UND FIR-SPEKTREN VON DIMETHYLDITHIOCARBAMATO-METALLCHELATEN Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197018381 |
0.222 |
|
| 2018 |
Luk J, Lu Y, Ackermann A, Peng X, Bogdan D, Puopolo M, Komatsu DE, Tong S, Ojima I, Rebecchi MJ, Kaczocha M. Contribution of diacylglycerol lipase β to pain after surgery. Journal of Pain Research. 11: 473-482. PMID 29551907 DOI: 10.2147/Jpr.S157208 |
0.222 |
|
| 1971 |
OJIMA I, ONISHI T, IWAMOTO T, INAMOTO N, TAMARU K. ChemInform Abstract: SYNTH. VON UEBERGANGSMETALLCHELATEN MIT DIPHENYLTHIOPHOSPHINYLTHIOHARNSTOFFEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197146045 |
0.221 |
|
| 1991 |
Ojima I, Donovan RJ, Clos N. Rhodium and cobalt carbonyl clusters Rh4(CO)12, Co2Rh2(CO)12, and Co3Rh(CO)12 as effective catalysts for hydrosilylation of isoprene, cyclohexanone, and cyclohexenone Organometallics. 10: 2606-2610. DOI: 10.1021/Om00054A020 |
0.22 |
|
| 2003 |
Brooks TA, Minderman H, O'Loughlin KL, Pera P, Ojima I, Baer MR, Bernacki RJ, Brooks T. Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Molecular Cancer Therapeutics. 2: 1195-205. PMID 14617793 |
0.22 |
|
| 2021 |
Artunduaga Bonilla JJ, Honorato L, Haranahalli K, Gremião IDF, Pereira SA, Guimarães A, Baptista ARS, de M Tavares P, Rodrigues ML, Miranda K, Ojima I, Del Poeta M, Nimrichter L. Antifungal activity of Acylhydrazone derivatives against spp. Antimicrobial Agents and Chemotherapy. PMID 33593845 DOI: 10.1128/AAC.02593-20 |
0.218 |
|
| 2021 |
Seborova K, Kloudova-Spalenkova A, Koucka K, Holy P, Ehrlichova M, Wang C, Ojima I, Voleska I, Daniel P, Balusikova K, Jelinek M, Kovar J, Rob L, Hruda M, Mrhalova M, et al. The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes. International Journal of Molecular Sciences. 23. PMID 35008510 DOI: 10.3390/ijms23010073 |
0.217 |
|
| 1991 |
Ojima I, Donovan RJ, Clos N. Rhodium and cobalt carbonyl clusters Rh4(CO)12, Co2Rh2(CO)12, and Co3Rh(CO)12 as effective catalysts for hydrosilylation of isoprene, cyclohexanone, and cyclohexenone [Erratum to document cited in CA115(13):136155e] Organometallics. 10: 3790-3790. DOI: 10.1021/Om00056A065 |
0.216 |
|
| 1981 |
OJIMA I. Report on the 2nd International Symposium on Homogeneous Catalysis Journal of Synthetic Organic Chemistry, Japan. 39: 415-422. DOI: 10.5059/Yukigoseikyokaishi.39.415 |
0.216 |
|
| 1970 |
OJIMA I, AKIBA K, INAMOTO N. ChemInform Abstract: RK. VON DIARYLPHOSPHINEN, IHREN OXIDEN UND SULFIDEN MIT ISOTHIOCYANATEN UND THIOCYANSAEURE Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197015362 |
0.215 |
|
| 1970 |
Ojima I, Onishi T, Iwamoto T, Inamoto N, Tamaru K. A new route to metal chelates of dimethyldithiocarbamate and their far infrared spectra Inorganic and Nuclear Chemistry Letters. 6: 65-69. DOI: 10.1016/0020-1650(70)80286-0 |
0.214 |
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| 2022 |
Wang C, Aguilar A, Ojima I. Strategies for the drug discovery and development of taxane anticancer therapeutics. Expert Opinion On Drug Discovery. 1-15. PMID 36200759 DOI: 10.1080/17460441.2022.2131766 |
0.214 |
|
| 2021 |
Ojima I. Recent advances in tumor-targeting chemotherapy drugs. Cancer Drug Resistance (Alhambra, Calif.). 4: 885-887. PMID 35309517 DOI: 10.20517/cdr.2021.86 |
0.209 |
|
| 1995 |
Ojima I. Recent Advances in the .beta.-Lactam Synthon Method Accounts of Chemical Research. 28: 383-389. DOI: 10.1021/Ar00057A004 |
0.209 |
|
| 1982 |
Fuchikami T, Ojima I. Remarkable dependency of regioselectivity on the catalyst metal species in the hydroformylation of trifluoropropene and pentafluorostyrene Journal of the American Chemical Society. 104: 3527-3529. DOI: 10.1021/Ja00376A057 |
0.208 |
|
| 1973 |
Ojima I, Inaba S, Kogure T, Nagai Y. The action of tris(triphenylphosphine)chlororhodium on polyhydromonosilanes Journal of Organometallic Chemistry. 55: C7-C8. DOI: 10.1016/S0022-328X(00)84018-8 |
0.207 |
|
| 2009 |
Ojima I. Synthetic organic chemists at a crossroads -challenges and possibilities- Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 67: 1093. DOI: 10.5059/Yukigoseikyokaishi.67.1093 |
0.205 |
|
| 1973 |
OJIMA I, KOGURE T, NAGAI Y. ChemInform Abstract: SELEKTIVE RED. VON ALPHA,BETA-UNGESAETTIGTEN TERPEN-CARBONYLVERBINDUNGEN MIT HYDROSILAN/RHODIUM(I)-KOMPLEX-MISCHUNGEN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197310208 |
0.205 |
|
| 2017 |
Ojima I. Great Challenges in Organic Chemistry. Frontiers in Chemistry. 5: 52. PMID 28748181 DOI: 10.3389/Fchem.2017.00052 |
0.202 |
|
| 2006 |
Varchi G, Ojima I. Synthesis of heterocycles through hydrosilylation, silylformylation, silylcarbocyclization and cyclohydrocarbonylation reactions Current Organic Chemistry. 10: 1341-1362. DOI: 10.2174/138527206778018230 |
0.201 |
|
| 1990 |
Ojima I, Zhang Z. Mechanism of amidocarbonylation: a stereochemical approach Organometallics. 9: 3122-3127. DOI: 10.1021/Om00162A025 |
0.198 |
|
| 1983 |
Ojima I. Book Reviews: Topics in Current Chemistry. Vol 105. Organic Chemistry Organometallics. 2: 941-941. DOI: 10.1021/Om50001A038 |
0.197 |
|
| 2002 |
Chin T, Sawamura S, Fujita H, Ojima I, Oyabu H, Nagakura Y, Otsuka H, Nakagawa A. %VO2max as an indicator of prosthetic rehabilitation outcome after dysvascular amputation Prosthetics and Orthotics International. 26: 44-49. PMID 12043925 DOI: 10.1080/03093640208726620 |
0.197 |
|
| 2009 |
Ojima I. Fluorine in Medicinal Chemistry and Chemical Biology Fluorine in Medicinal Chemistry and Chemical Biology. 1-624. DOI: 10.1002/9781444312096 |
0.195 |
|
| 1999 |
Ferlini C, Distefano M, Pierelli L, Bonanno G, Riva A, Bombardelli E, Ojima I, Mancuso S, Scambia G. Cytotoxic effects toward human hematopoietic progenitor cells and tumor cell lines of paclitaxel, docetaxel, and newly developed analogues IDN5109, IDN5111, and IDN5127 Oncology Research. 11: 471-478. PMID 10850888 |
0.191 |
|
| 2010 |
OJIMA I, TZAMARIOUDAKI M, EGUCHI M. ChemInform Abstract: New and Efficient Route to Pipecolic Acid Derivatives by Means of Rh- Catalyzed Intramolecular Cyclohydrocarbonylation. Cheminform. 27: no-no. DOI: 10.1002/chin.199612165 |
0.191 |
|
| 2021 |
Haranahalli K, Tong S, Kim S, Awwa M, Chen L, Knudson SE, Slayden RA, Singleton E, Russo R, Connell N, Ojima I. Structure-activity relationship studies on 2,5,6-trisubstituted benzimidazoles targeting -FtsZ as antitubercular agents. Rsc Medicinal Chemistry. 12: 78-94. PMID 34046600 DOI: 10.1039/d0md00256a |
0.191 |
|
| 1999 |
Chin T, Sawamura S, Fujita H, Nakajima S, Ojima I, Oyabu H, Nagakura Y, Otsuka H, Nakagawa A. The efficacy of physiological cost index (PCI) measurement of a subject walking with an Intelligent Prosthesis Prosthetics and Orthotics International. 23: 45-49. PMID 10355642 DOI: 10.3109/03093649909071609 |
0.19 |
|
| 2010 |
Ojima I, Moralee AC, Vassar VC. ChemInform Abstract: Recent Advances in Rhodium-Catalyzed Cyclization Reactions Cheminform. 33: no-no. DOI: 10.1002/chin.200252269 |
0.188 |
|
| 2010 |
ZHANG Z, OJIMA I. ChemInform Abstract: Syntheses of Nitrogen Heterocycles by Means of Amine-Directed Carbonylation and Hydrocarbonylation. Cheminform. 24: no-no. DOI: 10.1002/chin.199347083 |
0.186 |
|
| 1997 |
Chin T, Sawamura S, Fujita H, Nakajima S, Ojima I, Oyabu H, Nagakura Y, Nakagawa A. The efficacy of the one-leg cycling test for determining the anaerobic threshold (AT) of lower limb amputees Prosthetics and Orthotics International. 21: 141-146. PMID 9285958 DOI: 10.3109/03093649709164542 |
0.185 |
|
| 2021 |
Wang M, Wang C, Feng C, Guo W, Chen H, Liu B, Li E, Liu W, Taouil A, Ojima I, Hou P. Potent antitumor activity of novel taxoids in anaplastic thyroid cancer. Endocrine. PMID 34591230 DOI: 10.1007/s12020-021-02880-1 |
0.182 |
|
| 2004 |
Brooks TA, Kennedy DR, Gruol DJ, Ojima I, Baer MR, Bernacki RJ. Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators. Anticancer Research. 24: 409-15. PMID 15152938 |
0.177 |
|
| 2007 |
Ojima I. Editorial Current Topics in Medicinal Chemistry. 7: 457. DOI: 10.2174/156802607780059754 |
0.176 |
|
| 1996 |
Ojima I. Taxol®: Science and Applications Edited by Matthew Suffness. CRC Press, Boca Raton, FL. 1995. 426 pp. 18.5 × 26 cm. ISBN 0-8493-8382-X. $129.95. Journal of Medicinal Chemistry. 39: 807-807. DOI: 10.1021/Jm950752H |
0.173 |
|
| 2010 |
OJIMA I, HABUS I, ZHAO M, GEORG GI, JAYASINGHE LR. ChemInform Abstract: Efficient and Practical Asymmetric Synthesis of the Taxol C-13 Side Chain, N-Benzoyl-(2R,3S)-3-phenylisoserine, and Its Analogues via Chiral 3-Hydroxy-4-aryl-β-lactams Through Chiral Ester Enolate. Cheminform. 22: no-no. DOI: 10.1002/chin.199130137 |
0.172 |
|
| 2023 |
Hillowe A, Gordon C, Wang L, Rizzo RC, Trotman LC, Ojima I, Bialkowska A, Kaczocha M. Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells. Plos One. 18: e0292483. PMID 37796964 DOI: 10.1371/journal.pone.0292483 |
0.17 |
|
| 2023 |
Zhu C, Schutz L, Jayanetti K, Takemura K, Doswell F, Wang L, Ojima I, Kaczocha M. Truxillic acid monoamides as fatty acid binding protein 5 inhibitors. Bioorganic & Medicinal Chemistry. 94: 117464. PMID 37708641 DOI: 10.1016/j.bmc.2023.117464 |
0.17 |
|
| 2010 |
OJIMA I, KASS DF, ZHU J. ChemInform Abstract: New and Efficient Catalytic Route to Bicyclo(3.3.0)octa-1,5-dien-3- ones. Cheminform. 28: no-no. DOI: 10.1002/chin.199712081 |
0.166 |
|
| 1998 |
Ojima I. Asymmetric Synthesis.Garry Procter The Quarterly Review of Biology. 73: 492-492. DOI: 10.1086/420437 |
0.166 |
|
| 2010 |
OJIMA I, FRACCHIOLLA DA, DONOVAN RJ, BANERJI P. ChemInform Abstract: Silylcarbobicyclization of 1,6-Diynes: A Novel Catalytic Route to Bicyclo(3.3.0)octenones. Cheminform. 26: no-no. DOI: 10.1002/chin.199524080 |
0.165 |
|
| 2010 |
OJIMA I, HABUS I. ChemInform Abstract: Asymmetric Synthesis of β-Lactams by Chiral Ester Enolate-Imine Condensation. Cheminform. 22: no-no. DOI: 10.1002/chin.199134155 |
0.163 |
|
| 2005 |
Fujiwara M, Ojima I. Rhodium(I)-Catalyzed Cycloisomerization and Cyclotrimerization Reactions Modern Rhodium-Catalyzed Organic Reactions. 129-149. DOI: 10.1002/3527604693.ch7 |
0.162 |
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| 2010 |
OJIMA I, DONOVAN RJ, SHAY WR. ChemInform Abstract: Silylcarbocyclization Reactions Catalyzed by Rh and Rh-Co Complexes. Cheminform. 23: no-no. DOI: 10.1002/chin.199245220 |
0.161 |
|
| 2022 |
Morales D, Micheva-Viteva S, Adikari S, Werner J, Wolinsky M, Hong-Geller E, Kim J, Ojima I. Targeting the Bet-Hedging Strategy with an Inhibitor of Bacterial Efflux Capacity Enhances Antibiotic Efficiency and Ameliorates Bacterial Persistence In Vitro. Microorganisms. 10. PMID 36296242 DOI: 10.3390/microorganisms10101966 |
0.16 |
|
| 1987 |
OJIMA I. ChemInform Abstract: Novel Synthetic Routes to Organofluorine Compounds of Biological Interest Cheminform. 18. DOI: 10.1002/chin.198742369 |
0.158 |
|
| 2024 |
Sychra T, Spalenkova A, Balatka S, Vaclavikova R, Seborova K, Ehrlichova M, Truksa J, Sandoval-Acuña C, Nemcova V, Szabo A, Koci K, Tesarova T, Chen L, Ojima I, Oliverius M, et al. Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma. Iscience. 27: 109044. PMID 38357661 DOI: 10.1016/j.isci.2024.109044 |
0.158 |
|
| 2009 |
Kovár J, Ehrlichová M, Smejkalová B, Zanardi I, Ojima I, Gut I. Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells. Anticancer Research. 29: 2951-60. PMID 19661300 |
0.157 |
|
| 2021 |
Deng J, Yang Z, Ojima I, Samaras D, Wang F. Artificial intelligence in drug discovery: applications and techniques. Briefings in Bioinformatics. PMID 34734228 DOI: 10.1093/bib/bbab430 |
0.154 |
|
| 1979 |
OJIMA I, INABA S. ChemInform Abstract: KETENE SILYL ACETALS. NEW VERSATILE REAGENTS FOR ORGANIC SYNTHESIS Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197901390 |
0.153 |
|
| 2006 |
Ojima I. Discovery and Development of New Generation Taxane Anticancer Agents Cheminform. 37. DOI: 10.1002/chin.200607287 |
0.153 |
|
| 2023 |
M Swamynathan M, Mathew G, Aziz A, Gordon C, Hillowe A, Wang H, Jhaveri A, Kendall J, Cox H, Giarrizzo M, Azabdaftari G, Rizzo RC, Diermeier SD, Ojima I, Bialkowska AB, et al. FABP5 Inhibition against -Mutant Therapy Resistant Prostate Cancer. Cancers. 16. PMID 38201488 DOI: 10.3390/cancers16010060 |
0.153 |
|
| 1999 |
Ojima I, Inoue T, Slater JC, Lin S, Kuduk SD, Chakravarty S, Walsh JJ, Cresteil T, Monsarrat B, Pera P, Bernacki RJ. Synthesis of enatiopure fluorine-containing taxoids and their use as anticancer agents as well as probes for biomedical problems Acs Symposium Series. 746: 158-181. |
0.151 |
|
| 1988 |
OJIMA I, QIU X. ChemInform Abstract: Asymmetric Alkylation of Chiral β-Lactam Ester Enolates. A New Approach to the Synthesis of α-Alkylated α-Amino Acids. Cheminform. 19. DOI: 10.1002/chin.198806292 |
0.15 |
|
| 2010 |
Ojima I, Li Z, Zhu J. ChemInform Abstract: Recent Advances in Hydrosilylation and Related Reactions Cheminform. 30: no-no. DOI: 10.1002/chin.199915340 |
0.145 |
|
| 2010 |
OJIMA I, KUDUK SD, SLATER JC, GIMI RH, SUN CM, CHAKRAVARTY S, OUREVITCH M, ABOUABDELLAH A, BONNET-DELPON D, ET AL. EA. ChemInform Abstract: Syntheses, Biological Activity, and Conformational Analysis of Fluorine-Containing Taxoids Cheminform. 28: no-no. DOI: 10.1002/chin.199708256 |
0.144 |
|
| 2022 |
Seborova K, Koucka K, Spalenkova A, Holy P, Ehrlichova M, Sychra T, Chen L, Bendale H, Ojima I, Sandoval-Acuña C, Truksa J, Soucek P, Vaclavikova R. Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model. Frontiers in Pharmacology. 13: 971905. PMID 36438837 DOI: 10.3389/fphar.2022.971905 |
0.142 |
|
| 1990 |
OJIMA I, KATO K, NAKAHASHI K, FUCHIKAMI T, FUJITA M. ChemInform Abstract: New and Effective Routes to Fluoro Analogues of Aliphatic and Aromatic Amino Acids. Cheminform. 21. DOI: 10.1002/chin.199008312 |
0.14 |
|
| 2023 |
Daniel P, Balušíková K, Václavíková R, Šeborová K, Ransdorfová Š, Valeriánová M, Wei L, Jelínek M, Tlapáková T, Fleischer T, Kristensen VN, Souček P, Ojima I, Kovář J. Amplicon Contains Cyclic AMP Response Element-Driven Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines. Genes. 14. PMID 36833223 DOI: 10.3390/genes14020296 |
0.139 |
|
| 2010 |
OJIMA I, TZAMARIOUDAKI M, TSAI C. ChemInform Abstract: Extremely Chemoselective Silylformylation and Silylcarbocyclization of Alkynals. Cheminform. 25: no-no. DOI: 10.1002/chin.199434092 |
0.139 |
|
| 2010 |
OJIMA I, DONG Q. ChemInform Abstract: Synthesis of Fluorine-Containing Amino Acids by Means of Homogeneous Catalysis Cheminform. 27: no-no. DOI: 10.1002/chin.199603296 |
0.138 |
|
| 1999 |
Ojima I. Designin to treat multidrug-resistant tumors Modern Drug Discovery. 2: 45-52. |
0.136 |
|
| 2010 |
OJIMA I, WANG H, WANG T, NG EW. ChemInform Abstract: New Approaches to the Asymmetric Synthesis of Dipeptide Isosteres via β-Lactam Synthon Method. Cheminform. 29: no-no. DOI: 10.1002/chin.199821189 |
0.135 |
|
| 2023 |
Pereira de Sa N, Jayanetti K, Rendina D, Clement T, Soares Brauer V, Mota Fernandes C, Ojima I, Airola MV, Del Poeta M. Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections. Mbio. e0033923. PMID 36877042 DOI: 10.1128/mbio.00339-23 |
0.133 |
|
| 1999 |
Ojima I, Kuduk SD, Chakravarty S. Recent advances in the medicinal chemistry of taxoid anticancer agents Advances in Medicinal Chemistry. 4: 69-124. DOI: 10.1016/S1067-5698(99)80004-2 |
0.133 |
|
| 2021 |
Pereira de Sa N, Taouil A, Kim J, Clement T, Hoffmann RM, Burke JE, Rizzo RC, Ojima I, Del Poeta M, Airola MV. Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents. Nature Communications. 12: 5885. PMID 34620873 DOI: 10.1038/s41467-021-26163-5 |
0.132 |
|
| 1972 |
Ojima I, Kogure T. Selective reduction of α,β-unsaturated terpene carbonyl compounds using hydrosilane-rhodium(I) complex combinations Tetrahedron Letters. 13: 5035-5038. DOI: 10.1016/S0040-4039(01)85162-5 |
0.128 |
|
| 1985 |
OJIMA I, HIRAI K, FUJITA M, FUCHIKAMI T. ChemInform Abstract: NEW SYNTHETIC ROUTE TO N-ACYL α-AMINO ACIDS VIA AMIDOCARBONYLATION BY MEANS OF HOMOGENEOUS BINARY CATALYST SYSTEMS Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198522149 |
0.127 |
|
| 2010 |
OJIMA I, HABUS I, ZHAO M, ZUCCO M, PARK YH, SUN CM, BRIGAUD T. ChemInform Abstract: New and Efficient Approaches to the Semisynthesis of Taxol and Its C- 13 Side Chain Analogues by Means of β-Lactam Synthon Method. Cheminform. 23: no-no. DOI: 10.1002/chin.199250259 |
0.126 |
|
| 1998 |
Ojima I, Bounaud PY, Bernacki RJ. New weapons in the fight against cancer Chemtech. 28: 31-36. |
0.126 |
|
| 2007 |
Ojima I, Kuznetsova L, Ungureanu IM, Pepe A, Zanardi I, Chen J. Fluoro-β-lactams as Useful Building Blocks for the Synthesis of Fluorinated Amino Acids, Dipeptides, and Taxoids Cheminform. 38. DOI: 10.1002/chin.200720244 |
0.125 |
|
| 2010 |
OJIMA I, LI Z. ChemInform Abstract: Catalytic Activity of Rh, Rh-Co, and Ir-Co Multinuclear Complexes and Application to Organic Syntheses Cheminform. 29: no-no. DOI: 10.1002/chin.199826334 |
0.124 |
|
| 2024 |
Dib Ferreira Gremião I, Pereira-Oliveira GR, Pereira SA, Corrêa ML, Borba-Santos LP, Viçosa AL, Garg A, Haranahalli K, Dasilva D, Pereira de Sa N, Matos GS, Silva V, Lazzarini C, Fernandes CM, Miranda K, ... ... Ojima I, et al. Combination therapy of itraconazole and an acylhydrazone derivative (D13) for the treatment of sporotrichosis in cats. Microbiology Spectrum. e0396723. PMID 38647345 DOI: 10.1128/spectrum.03967-23 |
0.12 |
|
| 1971 |
OJIMA I, INAMOTO N. ChemInform Abstract: 1,2-CYCLOADDITION VON PHOSPHINOTHIOYL- UND SULFONYL-ISOTHIOCYANATEN MIT CARBODIIMIDEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/chin.197111011 |
0.119 |
|
| 1987 |
OJIMA I. ChemInform Abstract: Homogeneous Mixed-Metal Catalyst Systems: New and Effective Routes to N-Acyl-α-amino Acids via Carbonylations Cheminform. 18. DOI: 10.1002/chin.198742346 |
0.119 |
|
| 1975 |
Ojima I, Nihonyanagi M, Kogure T, Kumagai M, Horiuchi S, Nakatsugawa K, Nagai Y. Reduction of carbonyl compounds via hydrosilylation Journal of Organometallic Chemistry. 94: 449-461. DOI: 10.1016/s0022-328x(00)86954-5 |
0.115 |
|
| 1973 |
KONO H, OJIMA I, MATSUMOTO M, NAGAI Y. ChemInform Abstract: A CONVENIENT ROUTE TO AMINOSILANES USING HYDROSILANE-RHODIUM(I) COMPLEX COMBINATIONS Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197350373 |
0.114 |
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