Year |
Citation |
Score |
2024 |
Douville C, Lahouel K, Kuo A, Grant H, Avigdor BE, Curtis SD, Summers M, Cohen JD, Wang Y, Mattox A, Dudley J, Dobbyn L, Popoli M, Ptak J, Nehme N, ... ... Tomasetti C, et al. Machine learning to detect the SINEs of cancer. Science Translational Medicine. 16: eadi3883. PMID 38266106 DOI: 10.1126/scitranslmed.adi3883 |
0.344 |
|
2023 |
Mattox AK, Douville C, Wang Y, Popoli M, Ptak J, Silliman N, Dobbyn L, Schaefer J, Lu S, Pearlman AH, Cohen JD, Tie J, Gibbs P, Lahouel K, Bettegowda C, ... ... Tomasetti C, et al. The origin of highly elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer. Cancer Discovery. PMID 37565753 DOI: 10.1158/2159-8290.CD-21-1252 |
0.354 |
|
2022 |
Pénisson S, Lambert A, Tomasetti C. Evaluating cancer etiology and risk with a mathematical model of tumor evolution. Nature Communications. 13: 7224. PMID 36433937 DOI: 10.1038/s41467-022-34760-1 |
0.407 |
|
2021 |
Afsari B, Kuo A, Zhang Y, Li L, Lahouel K, Danilova L, Favorov A, Rosenquist TA, Grollman AP, Kinzler KW, Cope L, Vogelstein B, Tomasetti C. Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer. Elife. 10. PMID 33491650 DOI: 10.7554/eLife.61082 |
0.358 |
|
2020 |
Lennon AM, Buchanan AH, Kinde I, Warren A, Honushefsky A, Cohain AT, Ledbetter DH, Sanfilippo F, Sheridan K, Rosica D, Adonizio CS, Hwang HJ, Lahouel K, Cohen JD, Douville C, ... ... Tomasetti C, et al. Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention. Science (New York, N.Y.). PMID 32345712 DOI: 10.1126/Science.Abb9601 |
0.36 |
|
2020 |
Douville C, Cohen JD, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Schoen RE, Tie J, Gibbs P, Goggins M, Wolfgang CL, Wang TL, Shih IM, Karchin R, ... ... Tomasetti C, et al. Assessing aneuploidy with repetitive element sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 32075918 DOI: 10.1073/Pnas.1910041117 |
0.38 |
|
2019 |
Lahouel K, Younes L, Danilova L, Giardiello FM, Hruban RH, Groopman J, Kinzler KW, Vogelstein B, Geman D, Tomasetti C. Revisiting the tumorigenesis timeline with a data-driven generative model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31882448 DOI: 10.1073/Pnas.1914589117 |
0.457 |
|
2019 |
Tie J, Cohen JD, Wang Y, Christie M, Simons K, Lee M, Wong R, Kosmider S, Ananda S, McKendrick J, Lee B, Cho JH, Faragher I, Jones IT, Ptak J, ... ... Tomasetti C, et al. Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer. Jama Oncology. PMID 31621801 DOI: 10.1001/Jamaoncol.2019.3616 |
0.43 |
|
2019 |
Tomasetti C, Poling J, Roberts NJ, London NR, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B. Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence. Proceedings of the National Academy of Sciences of the United States of America. PMID 31548407 DOI: 10.1073/Pnas.1905722116 |
0.338 |
|
2019 |
Tomasetti C. Mutated clones are the new normal. Science (New York, N.Y.). 364: 938-939. PMID 31171683 DOI: 10.1126/Science.Aax5525 |
0.309 |
|
2019 |
Wang Y, Li L, Cohen JD, Kinde I, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Tie J, Gibbs P, Tomasetti C, Kinzler KW, Papadopoulos N, Vogelstein B, et al. Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer. Jama Oncology. PMID 31070668 DOI: 10.1001/Jamaoncol.2019.0512 |
0.426 |
|
2019 |
Eich ML, Rodriguez Pena MDC, Springer SU, Taheri D, Tregnago AC, Salles DC, Bezerra SM, Cunha IW, Fujita K, Ertoy D, Bivalacqua TJ, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, et al. Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31028363 DOI: 10.1038/S41379-019-0276-Y |
0.374 |
|
2019 |
Tie J, Cohen J, Wang Y, Li L, Lee M, Wong R, Kosmider S, Wong H, Lee B, Burge ME, Yip D, Karapetis CS, Price TJ, Tebbutt NC, Haydon AM, ... Tomasetti C, et al. A pooled analysis of multicenter cohort studies of post-surgery circulating tumor DNA (ctDNA) in early stage colorectal cancer (CRC). Journal of Clinical Oncology. 37: 3518-3518. DOI: 10.1200/Jco.2019.37.15_Suppl.3518 |
0.337 |
|
2019 |
Kubler K, Karlic R, Haradhvala NJ, Ha K, Kim J, Kuzman M, Jiao W, Gakkhar S, Mouw KW, Braunstein LZ, Elemento O, Biankin AV, Rooman I, Miller M, Nogiec CD, ... ... Tomasetti C, et al. Abstract 2727: The premalignant state captured in the landscape of somatic mutations can reveal the cancer cell-of-origin Cancer Research. 79: 2727-2727. DOI: 10.1158/1538-7445.Am2019-2727 |
0.468 |
|
2018 |
Wu RC, Wang P, Lin SF, Zhang M, Song Q, Chu T, Wang BG, Kurman RJ, Vang R, Kinzler K, Tomasetti C, Jiao Y, Shih IM, Wang TL. Genomic landscape and evolutionary trajectories of ovarian cancer early precursor lesions. The Journal of Pathology. PMID 30560554 DOI: 10.1002/Path.5219 |
0.318 |
|
2018 |
Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, ... ... Tomasetti C, et al. Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy. Elife. 7. PMID 30418154 DOI: 10.7554/Elife.43237 |
0.428 |
|
2018 |
Song M, Vogelstein B, Giovannucci EL, Willett WC, Tomasetti C. Cancer prevention: Molecular and epidemiologic consensus. Science (New York, N.Y.). 361: 1317-1318. PMID 30262488 DOI: 10.1126/Science.Aau3830 |
0.39 |
|
2018 |
Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang TL, Kurman RJ, Springer S, Ptak J, Popoli M, ... ... Tomasetti C, et al. Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers. Science Translational Medicine. 10. PMID 29563323 DOI: 10.1126/Scitranslmed.Aap8793 |
0.458 |
|
2018 |
Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, ... ... Tomasetti C, et al. Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy. Elife. 7. PMID 29557778 DOI: 10.7554/Elife.32143 |
0.464 |
|
2018 |
Tie J, Cohen JD, Wang Y, Li L, Christie M, Simons K, Elsaleh H, Kosmider S, Wong R, Yip D, Lee M, Tran B, Rangiah D, Burge M, Goldstein D, ... ... Tomasetti C, et al. Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study. Gut. PMID 29420226 DOI: 10.1136/Gutjnl-2017-315852 |
0.401 |
|
2018 |
Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, ... ... Tomasetti C, et al. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science (New York, N.Y.). PMID 29348365 DOI: 10.1126/Science.Aar3247 |
0.454 |
|
2018 |
Lee B, Lipton LR, Cohen J, Tie J, Javed AA, Li L, Goldstein D, Cooray P, Nagrial A, Burge ME, Tebbutt NC, Nikfarjam M, Harris M, Lennon AM, Wolfgang CL, ... Tomasetti C, et al. Circulating tumor DNA as a prognostic biomarker in early stage pancreatic cancer. Journal of Clinical Oncology. 36: e16206-e16206. DOI: 10.1200/Jco.2018.36.15_Suppl.E16206 |
0.39 |
|
2018 |
Tie J, Cohen J, Wang Y, Lee M, Wong R, Kosmider S, Ananda S, Cho JH, Faragher I, McKendrick JJ, Corfield C, Lee B, Field KM, Jones I, Li L, ... Tomasetti C, et al. Serial circulating tumor DNA (ctDNA) analysis as a prognostic marker and a real-time indicator of adjuvant chemotherapy (CT) efficacy in stage III colon cancer (CC). Journal of Clinical Oncology. 36: 3516-3516. DOI: 10.1200/Jco.2018.36.15_Suppl.3516 |
0.349 |
|
2018 |
Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang T, Kurman RJ, Springer S, Ptak J, Popoli M, ... ... Tomasetti C, et al. Evaluation of liquid from the papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers Obstetrical & Gynecological Survey. 73: 463-464. DOI: 10.1097/01.Ogx.0000542325.60681.A3 |
0.337 |
|
2017 |
Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, ... ... Tomasetti C, et al. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874546 DOI: 10.1073/Pnas.1704961114 |
0.469 |
|
2017 |
Tomasetti C, Durrett R, Kimmel M, Lambert A, Parmigiani G, Zauber A, Vogelstein B. Role of stem-cell divisions in cancer risk. Nature. 548: E13-E14. PMID 28796214 DOI: 10.1038/Nature23302 |
0.382 |
|
2017 |
Tomasetti C, Vogelstein B. On the slope of the regression between stem cell divisions and cancer risk, and the lack of correlation between stem cell divisions and environmental factors-associated cancer risk. Plos One. 12: e0175535. PMID 28520721 DOI: 10.1371/Journal.Pone.0175535 |
0.378 |
|
2017 |
Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, ... ... Tomasetti C, et al. Cancer-Associated Mutations in Endometriosis without Cancer. The New England Journal of Medicine. 376: 1835-1848. PMID 28489996 DOI: 10.1056/Nejmoa1614814 |
0.401 |
|
2017 |
Tomasetti C, Li L, Vogelstein B. Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention. Science (New York, N.Y.). 355: 1330-1334. PMID 28336671 DOI: 10.1126/Science.Aaf9011 |
0.478 |
|
2017 |
Lee B, Cohen J, Lipton LR, Tie J, Javed AA, Li L, Goldstein D, Cooray P, Nagrial A, Burge ME, Tebbutt NC, Nikfarjam M, Harris M, O'Broin-Lennon AM, Wolfgang CL, ... Tomasetti C, et al. Potential role of circulating tumor DNA (ctDNA) in the early diagnosis and post-operative management of localised pancreatic cancer. Journal of Clinical Oncology. 35: 4101-4101. DOI: 10.1200/Jco.2017.35.15_Suppl.4101 |
0.43 |
|
2017 |
Tie J, Cohen J, Wang Y, Li L, Kinde I, Elsaleh H, Wong R, Kosmider S, Yip D, Lee M, Tran B, Burge ME, Goldstein D, Singh MS, Diaz LA, ... Tomasetti C, et al. The potential of circulating tumor DNA (ctDNA) to guide adjuvant chemotherapy decision making in locally advanced rectal cancer (LARC). Journal of Clinical Oncology. 35: 3521-3521. DOI: 10.1200/Jco.2017.35.15_Suppl.3521 |
0.379 |
|
2016 |
Hoang ML, Kinde I, Tomasetti C, McMahon KW, Rosenquist TA, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N. Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528664 DOI: 10.1073/Pnas.1607794113 |
0.339 |
|
2016 |
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Silliman N, Tacey M, Wong HL, Christie M, Kosmider S, Skinner I, Wong R, Steel M, Tran B, et al. Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer. Science Translational Medicine. 8: 346ra92. PMID 27384348 DOI: 10.1126/Scitranslmed.Aaf6219 |
0.409 |
|
2016 |
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Wong R, Kosmider S, Tran B, Desai J, Hayes TM, Haydon AM, Yip D, Christie M, Strausberg R, et al. The potential of circulating tumor DNA (ctDNA) to reshape the design of clinical trials testing adjuvant therapy in patients with early stage cancers. Journal of Clinical Oncology. 34: 3511-3511. DOI: 10.1200/Jco.2016.34.15_Suppl.3511 |
0.419 |
|
2016 |
Hoang ML, Kinde I, Tomasetti C, Rosenquist T, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N. Abstract NG01: Accumulation of somatic mutations in normal and cancerous tissues with age Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ng01 |
0.416 |
|
2015 |
Tomasetti C, Vogelstein B. Cancer risk: role of environment—response Science (New York, N.Y.). 347: 729-731. PMID 25678653 DOI: 10.1126/Science.Aaa6592 |
0.446 |
|
2015 |
Tomasetti C, Vogelstein B. Variation in cancer risk among tissues can be explained by the number of stem cell divisions Science. 347: 78-81. PMID 25554788 DOI: 10.1126/Science.1260825 |
0.416 |
|
2015 |
Tomasetti C, Marchionni L, Nowak MA, Parmigiani G, Vogelstein B. Only three driver gene mutations are required for the development of lung and colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 112: 118-23. PMID 25535351 DOI: 10.1073/Pnas.1421839112 |
0.489 |
|
2015 |
Geman D, Ochs M, Price ND, Tomasetti C, Younes L. An argument for mechanism-based statistical inference in cancer Human Genetics. 134: 479-495. PMID 25381197 DOI: 10.1007/S00439-014-1501-X |
0.315 |
|
2015 |
Tomasetti C, Vogelstein B. Abstract LB-054: Normal stem cell divisions, cancer incidence, and driver gene mutations Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-054 |
0.489 |
|
2013 |
Tomasetti C, Vogelstein B, Parmigiani G. Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation Proceedings of the National Academy of Sciences of the United States of America. 110: 1999-2004. PMID 23345422 DOI: 10.1073/Pnas.1221068110 |
0.388 |
|
2012 |
Tomasetti C. On the probability of random genetic mutations for various types of tumor growth. Bulletin of Mathematical Biology. 74: 1379-95. PMID 22311065 DOI: 10.1007/S11538-012-9717-1 |
0.323 |
|
2012 |
Tomasetti C. Stochastic Modelling of Multiple Random Genetic Mutations Under the Cancer Stem Cell Hypothesis Mathematical Population Studies. 19: 200-213. DOI: 10.1080/08898480.2012.725379 |
0.416 |
|
2010 |
Tomasetti C, Levy D. Role of symmetric and asymmetric division of stem cells in developing drug resistance. Proceedings of the National Academy of Sciences of the United States of America. 107: 16766-71. PMID 20826440 DOI: 10.1073/Pnas.1007726107 |
0.347 |
|
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