John J. Lemasters - Publications

Affiliations: 
Biomedical Engineering Joint Program University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biomedical

352 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hu J, Nieminen AL, Weemhoff JL, Jaeschke H, Murphy LG, Dent JA, Lemasters JJ. The mitochondrial calcium uniporter mediates mitochondrial Fe uptake and hepatotoxicity after acetaminophen. Toxicology and Applied Pharmacology. 479: 116722. PMID 37848124 DOI: 10.1016/j.taap.2023.116722  0.361
2022 Kholmukhamedov A, Li L, Lindsey CC, Hu J, Nieminen AL, Takemoto K, Beeson GC, Beneker CM, McInnes C, Beeson CC, Lemasters JJ. A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria. The Journal of Biological Chemistry. 102336. PMID 35931111 DOI: 10.1016/j.jbc.2022.102336  0.304
2022 Adelusi OB, Ramachandran A, Lemasters JJ, Jaeschke H. The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicology and Applied Pharmacology. 445: 116043. PMID 35513057 DOI: 10.1016/j.taap.2022.116043  0.321
2022 Samuvel DJ, Li L, Krishnasamy Y, Gooz M, Takemoto K, Woster PM, Lemasters JJ, Zhong Z. Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice. Autophagy. 1-15. PMID 35293288 DOI: 10.1080/15548627.2022.2046457  0.327
2021 Lemasters JJ. Metabolic implications of non-Electrogenic ATP/ADP exchange in Cancer cells: A mechanistic basis for the Warburg effect. Biochimica Et Biophysica Acta. Bioenergetics. 148410. PMID 33722515 DOI: 10.1016/j.bbabio.2021.148410  0.301
2020 Wimborne HJ, Hu J, Takemoto K, Nguyen N, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization. Toxicology and Applied Pharmacology. 114982. PMID 32240663 DOI: 10.1016/J.Taap.2020.114982  0.473
2020 Hu J, Lemasters JJ. Suppression of iron mobilization from lysosomes to mitochondria attenuates liver injury after acetaminophen overdose in vivo in mice: Protection by minocycline. Toxicology and Applied Pharmacology. 114930. PMID 32109512 DOI: 10.1016/J.Taap.2020.114930  0.511
2020 Lemasters JJ, Jaeschke H. Oxidative Stress and Inflammation in the Liver Liver. 714-727. DOI: 10.1002/9781119436812.Ch55  0.313
2019 Krishnasamy Y, Gooz M, Li L, Lemasters JJ, Zhong Z. Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. International Journal of Physiology, Pathophysiology and Pharmacology. 11: 190-204. PMID 31777643  0.355
2019 Heslop KA, Rovini A, Hunt EG, Fang D, Morris ME, Christie CF, Gooz MB, DeHart DN, Dang Y, Lemasters JJ, Maldonado EN. JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells. Biochemical Pharmacology. 113728. PMID 31759978 DOI: 10.1016/J.Bcp.2019.113728  0.459
2019 Wimborne HJ, Takemoto K, Woster PM, Rockey DC, Lemasters JJ, Zhong Z. Aldehyde Dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice. Free Radical Biology & Medicine. PMID 31557514 DOI: 10.1016/J.Freeradbiomed.2019.09.026  0.375
2019 Oleinik N, Kim J, Roth BM, Selvam SP, Gooz M, Johnson RH, Lemasters JJ, Ogretmen B. Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. Science Advances. 5: eaax1978. PMID 31535025 DOI: 10.1126/Sciadv.Aax1978  0.398
2018 Lemasters JJ, Zhong Z. Mitophagy in hepatocytes: Types, initiators and role in adaptive ethanol metabolism☆. Liver Research. 2: 125-132. PMID 31157120 DOI: 10.1016/J.Livres.2018.09.005  0.458
2018 Jing R, Corbett JL, Cai J, Beeson GC, Beeson CC, Chan SS, Dimmock DP, Lazcares L, Geurts AM, Lemasters JJ, Duncan SA. A Screen Using iPSC-Derived Hepatocytes Reveals NAD as a Potential Treatment for mtDNA Depletion Syndrome. Cell Reports. 25: 1469-1484.e5. PMID 30404003 DOI: 10.1016/J.Celrep.2018.10.036  0.447
2018 Zhong Z, Lemasters JJ. A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease. Alcoholism, Clinical and Experimental Research. PMID 30132924 DOI: 10.1111/Acer.13877  0.42
2018 Mironova GD, Khrenov MO, Talanov EI, Glushkova OV, Parfenyuk SB, Novoselova TV, Lunin SM, Belosludtseva NV, Novoselova EG, Lemasters JJ. The role of mitochondrial KATP channel in anti-inflammatory effects of uridine in endotoxemic mice. Archives of Biochemistry and Biophysics. PMID 30009781 DOI: 10.1016/J.Abb.2018.07.006  0.317
2018 Ramshesh VK, Lemasters JJ. Imaging of Mitochondrial pH Using SNARF-1. Methods in Molecular Biology (Clifton, N.J.). 1782: 351-356. PMID 29851011 DOI: 10.1007/978-1-4939-7831-1_21  0.687
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Lemasters JJ, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.338
2018 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. Sa1514 - AMP-Activated Protein Kinase Protects Against Graft Injury after Liver Transplantation by Prevention of Mitochondrial Depolarization Gastroenterology. 154: S-1139. DOI: 10.1016/S0016-5085(18)33781-8  0.433
2018 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. Sa1511 - Amphiregulin Stimulates Mitochondrial Biogenesis after Small-For-Size Liver Transplantation in Mice Gastroenterology. 154: S-1138. DOI: 10.1016/S0016-5085(18)33778-8  0.429
2018 Krishnasamy Y, Gooz M, Li L, Lemasters JJ, Zhong Z. 512 - Role of Mitochondrial Depolarization and Disrupted Mitochondrial Homeostasis in Non-Alcoholic Steatohepatitis and Fibrosis Gastroenterology. 154: S-1095-S-1096. DOI: 10.1016/S0016-5085(18)33646-1  0.425
2017 Shoshan-Barmatz V, Kmita H, Lemasters JJ. Editorial: Uncovering the Function of the Mitochondrial Protein VDAC in Health and Disease: From Structure-Function to Novel Therapeutic Strategies. Frontiers in Oncology. 7: 320. PMID 29312890 DOI: 10.3389/Fonc.2017.00320  0.326
2017 Lemasters JJ. Evolution of Voltage-Dependent Anion Channel Function: From Molecular Sieve to Governator to Actuator of Ferroptosis. Frontiers in Oncology. 7: 303. PMID 29312883 DOI: 10.3389/Fonc.2017.00303  0.467
2017 DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN. Opening of Voltage Dependent Anion Channels Promotes Reactive Oxygen Species Generation, Mitochondrial Dysfunction and Cell Death in Cancer Cells. Biochemical Pharmacology. PMID 29289511 DOI: 10.1016/J.Bcp.2017.12.022  0.45
2017 Novgorodov SA, Voltin JR, Gooz MA, Li L, Lemasters JJ, Gudz TI. Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis. Journal of Lipid Research. PMID 29282302 DOI: 10.1194/Jlr.M080374  0.432
2017 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. 8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation. International Journal of Physiology, Pathophysiology and Pharmacology. 9: 69-83. PMID 28694919  0.382
2017 Teplova VV, Kruglov AG, Kovalyov LI, Nikiforova AB, Fedotcheva NI, Lemasters JJ. Glutamate contributes to alcohol hepatotoxicity by enhancing oxidative stress in mitochondria. Journal of Bioenergetics and Biomembranes. PMID 28478591 DOI: 10.1007/S10863-017-9713-0  0.359
2017 Lemasters JJ, Ramshesh VK, Lovelace GL, Lim J, Wright GD, Harland D, Dawson TL. Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire. The Journal of Investigative Dermatology. PMID 28344061 DOI: 10.1016/J.Jid.2017.02.983  0.744
2017 Krishnasamy Y, Lemasters JJ, Woster PM, Zhong Z. Inhibition of Lysine Specific Demethylase-1 (LSD1) Blocks Mitochondrial Dysfunction in Liver Ischemia/Reperfusion (I/R) Injury by Epigenetic Regulation of Antioxidative Pathways and JNK/SAB/P53/CYPD Interactions Gastroenterology. 152: S1067. DOI: 10.1016/S0016-5085(17)33604-1  0.435
2017 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. TGF-β Inhibition Stimulates Mitochondrial Biogenesis after Small-for-Size Liver Transplantation in Mice Gastroenterology. 152: S1065. DOI: 10.1016/S0016-5085(17)33595-3  0.405
2017 Krishnasamy Y, Lemasters JJ, Zhong Z. Inhibition of Sphingosine Kinase-2 by ABC294640 Suppresses Endotoxin-Induced Inflammatory Responses and Apoptosis in Mouse Livers Gastroenterology. 152: S1045-S1046. DOI: 10.1016/S0016-5085(17)33540-0  0.349
2017 Liu Q, Rehman H, Krishnasamy Y, Schnellmann RG, Lemasters JJ, Zhong Z. Suppression of Renal Mitochondrial Biogenesis (MB), a Novel Mechanism of Acute Kidney Injury (AKI) after Cholestatic Liver Fibrosis and Liver Transplantation (LT) Gastroenterology. 152: S1043. DOI: 10.1016/S0016-5085(17)33532-1  0.421
2017 Fang D, Heslop K, Morris M, DeHart D, Beck Gooz M, Lemasters JJ, Maldonado EN. Oxidative Stress Induced by Vdac Opening in Cancer Cells Depends on Cytosolic Free Tubulin and is Blocked by ROS Scavenging and Suppression of Superoxide Formation by Complex III Biophysical Journal. 112: 324a. DOI: 10.1016/J.Bpj.2016.11.1755  0.309
2016 Azarashvili T, Krestinina O, Baburina Y, Odinokova I, Akatov V, Beletsky I, Lemasters J, Papadopoulos V. Effect of the CRAC Peptide, VLNYYVW, on mPTP Opening in Rat Brain and Liver Mitochondria. International Journal of Molecular Sciences. 17. PMID 27983605 DOI: 10.3390/Ijms17122096  0.389
2016 Baburina Y, Odinokova I, Azarashvili T, Akatov V, Lemasters JJ, Krestinina O. 2',3'-Cyclic nucleotide 3'-phosphodiesterase as a messenger of protection of the mitochondrial function during melatonin treatment in aging. Biochimica Et Biophysica Acta. PMID 27836641 DOI: 10.1016/J.Bbamem.2016.11.003  0.418
2016 Krishnasamy Y, Ramshesh VK, Gooz M, Schnellmann RG, Lemasters JJ, Zhong Z. Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice. Plos One. 11: e0163342. PMID 27676640 DOI: 10.1371/Journal.Pone.0163342  0.685
2016 Maldonado EN, DeHart DN, Patnaik J, Klatt SC, Beck Gooz M, Lemasters JJ. ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells is Independent of the Adenine Nucleotide Translocator. The Journal of Biological Chemistry. PMID 27458020 DOI: 10.1074/Jbc.M116.734814  0.446
2016 Hu J, Kholmukhamedov A, Lindsey CC, Beeson CC, Jaeschke H, Lemasters JJ. Translocation of Iron from Lysosomes to Mitochondria during Acetaminophen-Induced Hepatocellular Injury: Protection by Starch-Desferal and Minocycline. Free Radical Biology & Medicine. PMID 27345134 DOI: 10.1016/J.Freeradbiomed.2016.06.024  0.459
2016 Rehman H, Liu Q, Krishnasamy Y, Shi Z, Ramshesh VK, Haque K, Schnellmann RG, Murphy MP, Lemasters JJ, Rockey DC, Zhong Z. The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice. International Journal of Physiology, Pathophysiology and Pharmacology. 8: 14-27. PMID 27186319  0.7
2016 DeHart DN, Gooz M, Lemasters JJ, Maldonado EN. Abstract A88: Openers of voltage dependent anion channels are anti-Warburg agents that enhance mitochondrial metabolism, decrease glycolysis, activate JNK and induce ROS-dependent killing of cancer cells Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A88  0.452
2016 Maldonado E, DeHart DN, Fang D, Heslop K, Beck Gooz M, Lemasters J. Oxidative Stress and JNK Activation cause Mitochondrial Dysfunction and Cell Death in Hepatocarcinoma after VDAC-Tubulin Antagonists Biophysical Journal. 110: 470a. DOI: 10.1016/J.Bpj.2015.11.2518  0.478
2016 Hu J, Kholmukhamedov A, Jaeschke H, Lemasters JJ, Nieminen A. Role of iron translocation to mitochondria via the mitochondrial Ca 2+ , Fe 2+ uniporter during acetaminophen hepatotoxicity Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1857: e118. DOI: 10.1016/J.Bbabio.2016.04.252  0.358
2016 Maldonado EN, DeHart DN, Patnaik J, Klatt SC, Gooz MB, Lemasters JJ. The adenine nucleotide translocator is not the exchanger of ATP/ADP between mitochondria and cytosol in cancer cells Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1857: e111. DOI: 10.1016/J.Bbabio.2016.04.238  0.361
2016 Rehman H, Liu Q, Krishnasamy Y, Shi Z, Ramshesh VK, Haque K, Schnellmann RG, Murphy MP, Lemasters JJ, Rockey DC, Zhong Z. The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice International Journal of Physiology, Pathophysiology and Pharmacology. 8: 14-27.  0.7
2015 Hu J, Ramshesh VK, McGill MR, Jaeschke H, Lemasters JJ. Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26721299 DOI: 10.1093/Toxsci/Kfv319  0.768
2015 Azarashvili T, Krestinina O, Baburina Y, Odinokova I, Grachev D, Papadopoulos V, Akatov V, Lemasters JJ, Reiser G. Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria. Archives of Biochemistry and Biophysics. 587: 70-7. PMID 26498031 DOI: 10.1016/J.Abb.2015.10.012  0.352
2015 Liu Q, Krishnasamy Y, Rehman H, Lemasters JJ, Schnellmann RG, Zhong Z. Disrupted Renal Mitochondrial Homeostasis after Liver Transplantation in Rats. Plos One. 10: e0140906. PMID 26480480 DOI: 10.1371/Journal.Pone.0140906  0.472
2015 Belosludtsev KN, Belosludtseva NV, Agafonov AV, Penkov NV, Samartsev VN, Lemasters JJ, Mironova GD. Effect of surface-potential modulators on the opening of lipid pores in liposomal and mitochondrial inner membranes induced by palmitate and calcium ions. Biochimica Et Biophysica Acta. 1848: 2200-5. PMID 26014488 DOI: 10.1016/J.Bbamem.2015.05.013  0.402
2015 Liu Q, Rehman H, Krishnasamy Y, Schnellmann RG, Lemasters JJ, Zhong Z. Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice. Journal of Hepatology. 63: 68-74. PMID 25703084 DOI: 10.1016/J.Jhep.2015.02.017  0.418
2015 Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Lemasters JJ, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137  0.331
2015 Krishnasamy Y, Shi Z, Lemasters JJ, Rockey DC, Zhong Z. Sa1685 Inhibition of Hepatic Stellate Cell Activation by MitoQ, a Mitochondrially Targeted Antioxidant Gastroenterology. 148: S-1011. DOI: 10.1016/S0016-5085(15)33453-3  0.453
2015 Shi Y, Rehman H, Krishnasamy Y, Schnellmann RG, Lemasters JJ, Zhong Z. Sa1681 Mitochondria-Targeting Antioxidant Attenuates Cholestasis-Induced Liver Fibrosis in Mice Gastroenterology. 148: S-1010. DOI: 10.1016/S0016-5085(15)33449-1  0.305
2015 Krishnasamy Y, Schnellmann RG, Remshash VK, Lemasters JJ, Zhong Z. 648 High Cholesterol and Ethanol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice Gastroenterology. 148: S-989. DOI: 10.1016/S0016-5085(15)33379-5  0.305
2015 Novgorodov SA, Gudz TI, Kholmukhamedov A, Deepe R, Lemasters JJ. Mitochondrial Iron and Sphingosine Synergize Initiation of Hepatocyte Death by Augmenting Oxidative Stress Biophysical Journal. 108: 611a-612a. DOI: 10.1016/J.Bpj.2014.11.3327  0.46
2015 Maldonado EN, Gooz M, DeHart DN, Lemasters JJ. VDAC Opening Drugs to Induce Mitochondrial Dysfunction and Cell Death Biophysical Journal. 108: 369a. DOI: 10.1016/J.Bpj.2014.11.2021  0.477
2015 Li L, Lemasters JJ. Glycine Protects Hepatocytes through a Chloride Independent Mechanism Biophysical Journal. 108: 327a. DOI: 10.1016/J.Bpj.2014.11.1781  0.394
2015 Rostovtseva TK, Gurnev PA, Hoogerheide DP, Maldonado EN, Lemasters JJ, Protchenko O, Lee JC, Bezrukov SM. High-Affinity Interaction with VDAC Links Cytosolic Proteins to Mitochondrial Regulation in Health, Cancer, and Neurodegeneration Biophysical Journal. 108: 189a. DOI: 10.1016/J.Bpj.2014.11.1047  0.396
2015 Lemasters JJ. Voltage Dependent Anion Channels (VDAC) and Regulation of Mitochondrial Metabolism Biophysical Journal. 108: 3a. DOI: 10.1016/J.Bpj.2014.11.032  0.467
2014 Maldonado EN, Lemasters JJ. ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect. Mitochondrion. 19: 78-84. PMID 25229666 DOI: 10.1016/J.Mito.2014.09.002  0.454
2014 Lemasters JJ. Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3). Redox Biology. 2: 749-54. PMID 25009776 DOI: 10.1016/J.Redox.2014.06.004  0.446
2014 Azarashvili T, Baburina Y, Grachev D, Krestinina O, Papadopoulos V, Lemasters JJ, Odinokova I, Reiser G. Carbenoxolone induces permeability transition pore opening in rat mitochondria via the translocator protein TSPO and connexin43. Archives of Biochemistry and Biophysics. 558: 87-94. PMID 24995971 DOI: 10.1016/J.Abb.2014.06.027  0.45
2014 Kholmukhamedov A, Czerny C, Hu J, Schwartz J, Zhong Z, Lemasters JJ. Minocycline and doxycycline, but not tetracycline, mitigate liver and kidney injury after hemorrhagic shock/resuscitation. Shock (Augusta, Ga.). 42: 256-63. PMID 24978888 DOI: 10.1097/Shk.0000000000000213  0.346
2014 Zhong Z, Ramshesh VK, Rehman H, Liu Q, Theruvath TP, Krishnasamy Y, Lemasters JJ. Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism. Plos One. 9: e91308. PMID 24618581 DOI: 10.1371/Journal.Pone.0091308  0.745
2014 Kholmukhamedov A, Spinale FG, Mukherjee R, Lemasters JJ. Reply to "letter to the editor: 'cyclosporin A in left ventricular remodeling after myocardial infarction'". American Journal of Physiology. Heart and Circulatory Physiology. 306: H778-9. PMID 24583826 DOI: 10.1152/Ajpheart.00021.2014  0.425
2014 Kholmukhamedov A, Logdon C, Hu J, McKinney RA, Spinale FG, Lemasters JJ, Mukherjee R. Cyclosporin A in left ventricular remodeling after myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 306: H53-9. PMID 24163074 DOI: 10.1152/Ajpheart.00079.2013  0.331
2014 Rehman H, Krishnasamy Y, Haque K, Thurman RG, Lemasters JJ, Schnellmann RG, Zhong Z. Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats. Plos One. 8: e65029. PMID 23755172 DOI: 10.1371/Journal.Pone.0065029  0.403
2014 Liu Q, Rehman H, Krishnasamy Y, Ramshesh VK, Schnellmann RG, Lemasters JJ, Zhong Z. Sa1036 Hepatic Fibrosis After Small-for-Size Liver Transplantation in Rats: Possible Role of TGFβ/SMAD Signaling Gastroenterology. 146: S-944. DOI: 10.1016/S0016-5085(14)63427-2  0.677
2014 Shi Y, Rehman H, Krishnasamy Y, Ramshesh VK, Schnellmann RG, Lemasters JJ, Murphy MP, Zhong Z. 771 Mitochondria-Targeting Antioxidant Attenuates Cholestasis-Induced Liver Injury in Mice Gastroenterology. 146: S-928. DOI: 10.1016/S0016-5085(14)63372-2  0.733
2014 DeHart DN, Gooz M, Rostovtseva TK, Sheldon KL, Lemasters JJ, Maldonado EN. Antagonists of the Inhibitory Effect of Free Tubulin on VDAC Induce Oxidative Stress and Mitochondrial Dysfunction Biophysical Journal. 106: 591a. DOI: 10.1016/J.Bpj.2013.11.3272  0.502
2014 Nieminen A, Schwartz J, Hung H, Blocker ER, Gooz M, Lemasters JJ. Mitoferrin-2 (MFRN2) Regulates the Electrogenic Mitochondrial Calcium Uniporter and Interacts Physically with MCU Biophysical Journal. 106: 581a-582a. DOI: 10.1016/J.Bpj.2013.11.3224  0.424
2014 Nieminen A, Schwartz JM, Hung H, Riley Blocker E, Gooz M, Lemasters JJ. Mitochondrial iron regulation: Interaction of Mitoferrin-2 (Mfrn2) and the electrogenic mitochondrial calcium uniporter (MCU) Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1837: e112-e113. DOI: 10.1016/J.Bbabio.2014.05.271  0.392
2014 DeHart DN, Gooz M, Rostovtseva TK, Sheldon KL, Lemasters JJ, Maldonado EN. Antagonists of tubulin–VDAC interaction induce oxidative stress and mitochondrial dysfunction Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1837: e111. DOI: 10.1016/J.Bbabio.2014.05.267  0.385
2014 Lemasters JJ. Cytolethality Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.01893-6  0.309
2013 Jetty R, Bandera YP, Daniele MA, Hanor D, Hung HI, Ramshesh V, Duperreault MF, Nieminen AL, Lemasters JJ, Foulger SH. Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging. Journal of Materials Chemistry. B. 1: 4542-4554. PMID 32261197 DOI: 10.1039/C3Tb20681E  0.667
2013 Wang XF, Florine-Casteel K, Lemasters JJ, Herman B. Video fluorescence microscopic techniques to monitor local lipid and phospholipid molecular order and organization in cell membranes during hypoxic injury. Journal of Fluorescence. 5: 71-84. PMID 24226613 DOI: 10.1007/Bf00718784  0.313
2013 Schwartz J, Holmuhamedov E, Zhang X, Lovelace GL, Smith CD, Lemasters JJ. Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. Toxicology and Applied Pharmacology. 273: 172-9. PMID 24012766 DOI: 10.1016/J.Taap.2013.08.027  0.461
2013 Czaja MJ, Ding WX, Donohue TM, Friedman SL, Kim JS, Komatsu M, Lemasters JJ, Lemoine A, Lin JD, Ou JH, Perlmutter DH, Randall G, Ray RB, Tsung A, Yin XM. Functions of autophagy in normal and diseased liver. Autophagy. 9: 1131-58. PMID 23774882 DOI: 10.4161/Auto.25063  0.398
2013 Kholmukhamedov A, Schwartz JM, Lemasters JJ. Isolated mitochondria infusion mitigates ischemia-reperfusion injury of the liver in rats: mitotracker probes and mitochondrial membrane potential. Shock (Augusta, Ga.). 39: 543. PMID 23680774 DOI: 10.1097/Shk.0B013E318292300D  0.507
2013 Zhang X, Lemasters JJ. Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes. Free Radical Biology & Medicine. 63: 243-53. PMID 23665427 DOI: 10.1016/J.Freeradbiomed.2013.05.004  0.484
2013 Maldonado EN, Sheldon KL, DeHart DN, Patnaik J, Manevich Y, Townsend DM, Bezrukov SM, Rostovtseva TK, Lemasters JJ. Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin. The Journal of Biological Chemistry. 288: 11920-9. PMID 23471966 DOI: 10.1074/Jbc.M112.433847  0.462
2013 He S, Rehman H, Shi Y, Krishnasamy Y, Lemasters JJ, Schnellmann RG, Zhong Z. Suramin decreases injury and improves regeneration of ethanol-induced steatotic partial liver grafts. The Journal of Pharmacology and Experimental Therapeutics. 344: 417-25. PMID 23161217 DOI: 10.1124/Jpet.112.199919  0.39
2013 Hung HI, Schwartz JM, Maldonado EN, Lemasters JJ, Nieminen AL. Mitoferrin-2-dependent mitochondrial iron uptake sensitizes human head and neck squamous carcinoma cells to photodynamic therapy. The Journal of Biological Chemistry. 288: 677-86. PMID 23135267 DOI: 10.1074/Jbc.M112.422667  0.398
2013 Jetty R, Bandera YP, Daniele MA, Hanor D, Hung HI, Ramshesh V, Duperreault MF, Nieminen AL, Lemasters JJ, Foulger SH. Protein triggered fluorescence switching of near-infrared emitting nanoparticles for contrast-enhanced imaging Journal of Materials Chemistry B. 1: 4542-4554. DOI: 10.1039/c3tb20681e  0.637
2013 Liu Q, Rehman H, Krishnasamy Y, Haque K, Lemasters JJ, Schnellmann RG, Zhong Z. Mo1841 Formoterol Stimulates Mitochondrial Biogenesis and Improves Regeneration and Function of Remnant Livers After Ischemia/Reperfusion and Partial Hepatectomy Gastroenterology. 144: S-1026. DOI: 10.1016/S0016-5085(13)63815-9  0.404
2013 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. Mo1786 8-Pcpt-cGMP Protects Against Mitochondrial Dysfunction and Improves Survival of Steatotic Grafts After Partial Liver Transplantation Gastroenterology. 144: S-1026. DOI: 10.1016/S0016-5085(13)63813-5  0.412
2013 Rehman H, Krishnasamy Y, Ramshesh VK, Schnellmann RG, Lemasters JJ, Zhong Z. 296 Activation of Aldehyde Dehydrogenase-2 Prevents Acute Ethanol-Induced Liver Mitochondrial Depolarization and Steatosis in Mice Gastroenterology. 144: S-940. DOI: 10.1016/S0016-5085(13)63498-8  0.746
2013 Maldonado EN, Vuicich J, DeHart DN, Rodebaugh HS, Lemasters JJ. Translocation of Glycolytic ATP into Mitochondria of Cancer Cells does not Utilize the Adenine Nucleotide Transporter Biophysical Journal. 104: 303a-304a. DOI: 10.1016/J.Bpj.2012.11.1689  0.45
2013 Lemasters JJ. Hepatotoxicity Due to mitochondrial injury Drug-Induced Liver Disease. 85-100. DOI: 10.1016/B978-0-12-387817-5.00005-4  0.401
2012 Schemmer P, Lemasters JJ, Clavien PA. Ischemia/Reperfusion injury in liver surgery and transplantation. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2012: 453295. PMID 23345924 DOI: 10.1155/2012/453295  0.387
2012 Sentelle RD, Senkal CE, Jiang W, Ponnusamy S, Gencer S, Selvam SP, Ramshesh VK, Peterson YK, Lemasters JJ, Szulc ZM, Bielawski J, Ogretmen B. Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy. Nature Chemical Biology. 8: 831-8. PMID 22922758 DOI: 10.1038/Nchembio.1059  0.748
2012 Woolbright BL, Ramachandran A, McGill MR, Yan HM, Bajt ML, Sharpe MR, Lemasters JJ, Jaeschke H. Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity. Basic & Clinical Pharmacology & Toxicology. 111: 417-25. PMID 22900545 DOI: 10.1111/J.1742-7843.2012.00931.X  0.375
2012 Currin RT, Peng XX, Lemasters JJ. Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2012: 236406. PMID 22888183 DOI: 10.1155/2012/236406  0.363
2012 Liu Q, Rehman H, Shi Y, Krishnasamy Y, Lemasters JJ, Smith CD, Zhong Z. Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats. Plos One. 7: e41834. PMID 22848628 DOI: 10.1371/Journal.Pone.0041834  0.368
2012 Czerny C, Theruvath TP, Maldonado EN, Lehnert M, Marzi I, Zhong Z, Lemasters JJ. C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2012: 641982. PMID 22791932 DOI: 10.1155/2012/641982  0.421
2012 Theruvath TP, Ramshesh VK, Zhong Z, Currin RT, Karrasch T, Lemasters JJ. Icam-1 upregulation in ethanol-induced Fatty murine livers promotes injury and sinusoidal leukocyte adherence after transplantation. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2012: 480893. PMID 22778492 DOI: 10.1155/2012/480893  0.708
2012 Czerny C, Kholmukhamedov A, Theruvath TP, Maldonado EN, Ramshesh VK, Lehnert M, Marzi I, Zhong Z, Lemasters JJ. Minocycline decreases liver injury after hemorrhagic shock and resuscitation in mice. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2012: 259512. PMID 22719175 DOI: 10.1155/2012/259512  0.747
2012 Maldonado EN, Lemasters JJ. Warburg revisited: regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 342: 637-41. PMID 22700429 DOI: 10.1124/Jpet.112.192153  0.436
2012 Liu Q, Rehman H, Krishnasamy Y, Haque K, Schnellmann RG, Lemasters JJ, Zhong Z. Amphiregulin stimulates liver regeneration after small-for-size mouse liver transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 2052-61. PMID 22694592 DOI: 10.1111/J.1600-6143.2012.04069.X  0.335
2012 Liu Q, Rehman H, Harley RA, Lemasters JJ, Zhong Z. Small-for-Size Liver Transplantation Increases Pulmonary Injury in Rats: Prevention by NIM811. Hpb Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery. 2012: 270372. PMID 22675237 DOI: 10.1155/2012/270372  0.358
2012 Liu Q, Rehman H, Krishnasamy Y, Ramshesh VK, Theruvath TP, Chavin KD, Schnellmann RG, Lemasters JJ, Zhong Z. Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers. Free Radical Biology & Medicine. 53: 250-9. PMID 22609250 DOI: 10.1016/J.Freeradbiomed.2012.05.012  0.76
2012 Dolganiuc A, Thomes PG, Ding WX, Lemasters JJ, Donohue TM. Autophagy in alcohol-induced liver diseases. Alcoholism, Clinical and Experimental Research. 36: 1301-8. PMID 22551004 DOI: 10.1111/J.1530-0277.2012.01742.X  0.356
2012 Kim JS, Wang JH, Lemasters JJ. Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: role of Ca2+-dependent mitochondrial formation of reactive oxygen species. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G723-31. PMID 22241863 DOI: 10.1152/Ajpgi.00082.2011  0.479
2012 Holmuhamedov EL, Czerny C, Beeson CC, Lemasters JJ. Ethanol suppresses ureagenesis in rat hepatocytes: role of acetaldehyde. The Journal of Biological Chemistry. 287: 7692-700. PMID 22228763 DOI: 10.1074/Jbc.M111.293399  0.375
2012 Saggu S, Hung HI, Quiogue G, Lemasters JJ, Nieminen AL. Lysosomal signaling enhances mitochondria-mediated photodynamic therapy in A431 cancer cells: role of iron. Photochemistry and Photobiology. 88: 461-8. PMID 22220628 DOI: 10.1111/J.1751-1097.2012.01081.X  0.374
2012 Lemasters JJ, Holmuhamedov EL, Czerny C, Zhong Z, Maldonado EN. Regulation of mitochondrial function by voltage dependent anion channels in ethanol metabolism and the Warburg effect. Biochimica Et Biophysica Acta. 1818: 1536-44. PMID 22172804 DOI: 10.1016/J.Bbamem.2011.11.034  0.456
2012 Ramshesh VK, Lemasters JJ. Imaging of mitochondrial pH using SNARF-1. Methods in Molecular Biology (Clifton, N.J.). 810: 243-8. PMID 22057572 DOI: 10.1007/978-1-61779-382-0_16  0.699
2012 Koch DG, Bogatkevich G, Ramshesh V, Lemasters JJ, Uflacker R, Reuben A. Elevated levels of endothelin-1 in hepatic venous blood are associated with intrapulmonary vasodilatation in humans. Digestive Diseases and Sciences. 57: 516-23. PMID 21964742 DOI: 10.1007/S10620-011-1905-6  0.661
2012 Shi Y, Rehman H, Ramshesh VK, Schwartz J, Liu Q, Krishnasamy Y, Zhang X, Lemasters JJ, Smith CD, Zhong Z. Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. Journal of Hepatology. 56: 137-45. PMID 21756852 DOI: 10.1016/J.Jhep.2011.05.025  0.775
2012 Hung H, Lemasters JJ, Nieminen A. Abstract 2281: Signaling from lysosomes to mitochondria sensitizes head and neck cancer cells to photodynamic treatment: Role of mitoferrin 2 Cancer Research. 72: 2281-2281. DOI: 10.1158/1538-7445.Am2012-2281  0.367
2012 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. iNOS-Deficiency Prevents C-Jun-N-Terminal Kinase Activation and Mitochondrial Dysfunction after Non-Heart-Beating Liver Transplantation in Mice Transplantation Journal. 94: 678. DOI: 10.1097/00007890-201211271-01330  0.407
2012 Liu Q, Rehman H, Krishnasamy Y, Haque K, Schnellmann RG, Lemasters JJ, Zhong Z. Role of Amphiregulin in Suppressed Liver Regeneration after Small-For-Size Liver Transplantation in Mice Transplantation Journal. 94: 376. DOI: 10.1097/00007890-201211271-00694  0.342
2012 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Schnellmann RG, Zhong Z. Mo1915 Daidzein Improves Mitochondrial Biogenesis in Small-for-Size Mouse Liver Grafts Gastroenterology. 142: S-998. DOI: 10.1016/S0016-5085(12)63868-2  0.455
2012 Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z. Mo1914 JNK2, but Not JNK1, Contributes to Mitochondrial Depolarization and Graft Failure After Non-Heart-Beating Liver Transplantation in Mice Gastroenterology. 142: S-998. DOI: 10.1016/S0016-5085(12)63867-0  0.328
2012 Rehman H, Liu Q, Haque K, Krishnasamy Y, Ramshesh VK, Lemasters JJ, Murphy MP, Zhong Z. 1022 Mitochondria-Targeting Antioxidant Attenuates Carbon Tetracholride-Induced Liver Fibrosis Gastroenterology. 142: S-942. DOI: 10.1016/S0016-5085(12)63650-6  0.719
2012 Maldonado EN, DeHart DN, Patnaik JR, Sheldon KL, Rostovtseva TK, Manevich Y, Townsend D, Lemasters JJ. Voltage Dependent Anion Channel-3 (VDAC3) is the Major Isoform Contributing to Mitochondrial Metabolism in HepG2 Cells and is Regulated by Free Tubulin and Erastin Biophysical Journal. 102: 573a. DOI: 10.1016/J.Bpj.2011.11.3118  0.44
2012 Sheldon KL, Maldonado EN, Lemasters JJ, Bezrukov SM, Rostovtseva TK. VDAC Phosphorylation in Control of Mitochondrial Respiration Biophysical Journal. 102: 436a-437a. DOI: 10.1016/J.Bpj.2011.11.2390  0.41
2011 Sheldon KL, Maldonado EN, Lemasters JJ, Rostovtseva TK, Bezrukov SM. Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. Plos One. 6: e25539. PMID 22022409 DOI: 10.1371/Journal.Pone.0025539  0.383
2011 Bajt ML, Ramachandran A, Yan HM, Lebofsky M, Farhood A, Lemasters JJ, Jaeschke H. Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 122: 598-605. PMID 21572097 DOI: 10.1093/Toxsci/Kfr116  0.459
2011 Rehman H, Sun J, Shi Y, Ramshesh VK, Liu Q, Currin RT, Lemasters JJ, Zhong Z. NIM811 prevents mitochondrial dysfunction, attenuates liver injury, and stimulates liver regeneration after massive hepatectomy. Transplantation. 91: 406-12. PMID 21131897 DOI: 10.1097/Tp.0B013E318204Bdb2  0.785
2011 Kim I, Lemasters JJ. Mitophagy selectively degrades individual damaged mitochondria after photoirradiation. Antioxidants & Redox Signaling. 14: 1919-28. PMID 21126216 DOI: 10.1089/Ars.2010.3768  0.702
2011 Kim I, Lemasters JJ. Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation. American Journal of Physiology. Cell Physiology. 300: C308-17. PMID 21106691 DOI: 10.1152/Ajpcell.00056.2010  0.708
2011 Ramachandran A, Lebofsky M, Baines CP, Lemasters JJ, Jaeschke H. Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury. Free Radical Research. 45: 156-64. PMID 20942566 DOI: 10.3109/10715762.2010.520319  0.432
2011 Hung HI, Quiogue G, Lemasters JJ, Nieminen AL. Signaling from lysosomes to mitochondria sensitizes cancer cells to photodynamic treatment Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7886. DOI: 10.1117/12.878306  0.428
2011 Rehman H, Krishnasamy Y, Shi Y, Zhang X, Lemasters JJ, Smith CD, Zhong Z. Sphingosine Kinase-2 Plays an Important Role in Ischemia/Reperfusion-Induced Hepatocyte Death Gastroenterology. 140: S-977. DOI: 10.1016/S0016-5085(11)64048-1  0.302
2011 Liu Q, Rehman H, Ramshesh VK, Shi Y, Lemasters JJ, Zhong Z. Female Mice Are More Susceptible to Ethanol-Induced Mitochondrial Depolarization: Studies by Intravital Multiphoton Microscopy Gastroenterology. 140: S-915. DOI: 10.1016/S0016-5085(11)63794-3  0.682
2011 Holmuhamedov EL, Lovelace G, Lemasters JJ. Aldehyde Products of Ethanol Oxidation and Oxidative Stress Suppress Ureagenic but not Basal Respiration of Cultured Hepatocytes Biophysical Journal. 100: 460a. DOI: 10.1016/J.Bpj.2010.12.2704  0.305
2011 Maldonado EN, DeHart DN, Patnaik JR, Lemasters JJ. Knockdown of VDAC Isoforms Decreases Mitochondrial Membrane Potential and Modulates the Effects of Free Tubulin in HepG2 Hepatoma Cells Biophysical Journal. 100: 459a-460a. DOI: 10.1016/J.Bpj.2010.12.2703  0.422
2010 Maldonado EN, Patnaik J, Mullins MR, Lemasters JJ. Free tubulin modulates mitochondrial membrane potential in cancer cells. Cancer Research. 70: 10192-201. PMID 21159641 DOI: 10.1158/0008-5472.Can-10-2429  0.391
2010 Kholmukhamedov EL, Czerny C, Lovelace G, Beeson KC, Baker T, Johnson CB, Pediaditakis P, Teplova VV, Tikunov A, MacDonald J, Lemasters JJ. [The role of the voltage-dependent anion channels in the outer membrane of mitochondria in the regulation of cellular metabolism]. Biofizika. 55: 822-33. PMID 21033348  0.345
2010 Pediaditakis P, Kim JS, He L, Zhang X, Graves LM, Lemasters JJ. Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes. The Biochemical Journal. 431: 411-21. PMID 20738255 DOI: 10.1042/Bj20091741  0.46
2010 Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 515-23. PMID 20616211 DOI: 10.1093/Toxsci/Kfq208  0.468
2010 Kon K, Kim JS, Uchiyama A, Jaeschke H, Lemasters JJ. Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 101-8. PMID 20584761 DOI: 10.1093/Toxsci/Kfq175  0.402
2010 Saito C, Lemasters JJ, Jaeschke H. c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. Toxicology and Applied Pharmacology. 246: 8-17. PMID 20423716 DOI: 10.1016/J.Taap.2010.04.015  0.473
2010 Zhong Z, Tsukada S, Rehman H, Parsons CJ, Theruvath TP, Rippe RA, Brenner DA, Lemasters JJ. Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 16: 181-90. PMID 20104486 DOI: 10.1002/Lt.21966  0.311
2010 Tikunov A, Johnson CB, Pediaditakis P, Markevich N, Macdonald JM, Lemasters JJ, Holmuhamedov E. Closure of VDAC causes oxidative stress and accelerates the Ca(2+)-induced mitochondrial permeability transition in rat liver mitochondria. Archives of Biochemistry and Biophysics. 495: 174-81. PMID 20097153 DOI: 10.1016/J.Abb.2010.01.008  0.452
2010 Holmuhamedov EL, Czerny C, Lovelace G, Beeson CC, Baker T, Johnson CB, Pediaditakis P, Teplova VV, Tikunov A, MacDonald J, Lemasters JJ. Role of voltage-dependent anion channels of the mitochondrial outer membrane in regulation of cell metabolism Biophysics. 55: 733-739. DOI: 10.1134/S0006350910050088  0.466
2010 Rehman H, Ramshesh VK, Theruvath TP, Lemasters JJ, Zhong Z. OVER-EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN ETHANOL-INDUCED FATTY LIVERS AFTER TRANSPLANTATION: ITS RELATION TO MITOCHONDRIAL DYSFUNCTION AND GRAFT INJURY Transplantation Journal. 90: 173. DOI: 10.1097/00007890-201007272-00335  0.749
2010 Shi Y, Rehman H, Lemasters JJ, Smith CD, Zhong Z. M1678 Sphingosine Kinase is Involved in Oxidative and Nitrative Stress After Liver Ischemia/Reperfusion Gastroenterology. 138: S-828. DOI: 10.1016/S0016-5085(10)63815-2  0.314
2010 Maldonado EN, Patnaik JR, Lemasters JJ. Free Tubulin and cAMP-Dependent Phosphorylation Modulate Mitochondrial Membrane Potential in Hepg2 Cells: Possible Role of VDAC Biophysical Journal. 98: 735a. DOI: 10.1016/J.Bpj.2009.12.4031  0.42
2010 Zhang X, Schwartz J, Ramshesh VK, Pediaditakis P, Holmuhamedov E, Zhong Z, Theruvath TP, Lemasters JJ. Minocycline protects against the mitochondria permeability transition after both warm and cold ischemia-reperfusion Hepatology. 51: 349-350. DOI: 10.1002/Hep.23453  0.713
2009 Rodriguez-Enriquez S, Kai Y, Maldonado E, Currin RT, Lemasters JJ. Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes. Autophagy. 5: 1099-106. PMID 19783904 DOI: 10.4161/Auto.5.8.9825  0.44
2009 Lemasters JJ, Theruvath TP, Zhong Z, Nieminen AL. Mitochondrial calcium and the permeability transition in cell death. Biochimica Et Biophysica Acta. 1787: 1395-401. PMID 19576166 DOI: 10.1016/J.Bbabio.2009.06.009  0.436
2009 Holmuhamedov E, Lemasters JJ. Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes. Archives of Biochemistry and Biophysics. 481: 226-33. PMID 19014900 DOI: 10.1016/J.Abb.2008.10.036  0.442
2009 Rehman H, Lemasters JJ, Zhong Z. 174 Plant Polyphenols Prevent Suppression of Mitochondrial Biogenesis in Small-for-Size Liver Grafts Gastroenterology. 136: A-794. DOI: 10.1016/S0016-5085(09)63664-7  0.429
2009 Zhong Z, Sun J, Currin R, Lemasters JJ. 2 NIM811 Inhibits Mitochondrial Dysfunction, Prevents Liver Injury and Stimulates Liver Regeneration After Massive Hepatectomy Gastroenterology. 136: A-789. DOI: 10.1016/S0016-5085(09)63640-4  0.462
2009 Theruvath TP, Chavin KD, Zhong Z, Lemasters JJ. ICAM-1 upregulation in alcohol-induced fatty mouse livers promotes reperfusion injury after transplantation through increased oxidative stress and downstream leukocyte adherence Journal of the American College of Surgeons. 209: S60. DOI: 10.1016/J.Jamcollsurg.2009.06.143  0.365
2009 Lemasters JJ. Molecular Mechanisms of Cell Death Cell Death & Differentiation. 25: 1-18. DOI: 10.1016/B978-0-12-374419-7.00001-9  0.335
2008 Ramshesh VK, Lemasters JJ. Pinhole shifting lifetime imaging microscopy. Journal of Biomedical Optics. 13: 064001. PMID 19123648 DOI: 10.1117/1.3027503  0.659
2008 Brookes PS, Parker N, Buckingham JA, Vidal-Puig A, Halestrap AP, Gunter TE, Nicholls DG, Bernardi P, Lemasters JJ, Brand MD. UCPs--unlikely calcium porters. Nature Cell Biology. 10: 1235-7; author reply. PMID 18978830 DOI: 10.1038/Ncb1108-1235  0.353
2008 Uchiyama A, Kim JS, Kon K, Jaeschke H, Ikejima K, Watanabe S, Lemasters JJ. Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology (Baltimore, Md.). 48: 1644-54. PMID 18846543 DOI: 10.1002/Hep.22498  0.425
2008 Rehman H, Ramshesh VK, Theruvath TP, Kim I, Currin RT, Giri S, Lemasters JJ, Zhong Z. NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice. The Journal of Pharmacology and Experimental Therapeutics. 327: 699-706. PMID 18801946 DOI: 10.1124/Jpet.108.143578  0.829
2008 Zhong Z, Ramshesh VK, Rehman H, Currin RT, Sridharan V, Theruvath TP, Kim I, Wright GL, Lemasters JJ. Activation of the oxygen-sensing signal cascade prevents mitochondrial injury after mouse liver ischemia-reperfusion. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G823-32. PMID 18772364 DOI: 10.1152/Ajpgi.90287.2008  0.841
2008 Theruvath TP, Czerny C, Ramshesh VK, Zhong Z, Chavin KD, Lemasters JJ. C-Jun N-terminal kinase 2 promotes graft injury via the mitochondrial permeability transition after mouse liver transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 1819-28. PMID 18671679 DOI: 10.1111/J.1600-6143.2008.02336.X  0.732
2008 Theruvath TP, Snoddy MC, Zhong Z, Lemasters JJ. Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2. Transplantation. 85: 1500-4. PMID 18497693 DOI: 10.1097/Tp.0B013E31816Fefb5  0.478
2008 Rehman H, Connor HD, Ramshesh VK, Theruvath TP, Mason RP, Wright GL, Lemasters JJ, Zhong Z. Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts. Transplantation. 85: 1322-31. PMID 18475191 DOI: 10.1097/Tp.0B013E31816De302  0.768
2008 Theruvath TP, Zhong Z, Pediaditakis P, Ramshesh VK, Currin RT, Tikunov A, Holmuhamedov E, Lemasters JJ. Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology (Baltimore, Md.). 47: 236-46. PMID 18023036 DOI: 10.1002/Hep.21912  0.763
2008 Bajt ML, Farhood A, Lemasters JJ, Jaeschke H. Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity. The Journal of Pharmacology and Experimental Therapeutics. 324: 8-14. PMID 17906064 DOI: 10.1124/Jpet.107.129445  0.428
2008 Nieminen AL, Azizuddin K, Zhang P, Kenney ME, Pediaditakis P, Lemasters JJ, Oleinick NL. Contribution of mitochondria and lysosomes to photodynamic therapy-induced death in cancer cells Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6845. DOI: 10.1117/12.767356  0.484
2008 Zhong Z, Rehman H, Theruvath T, Lemasters J. INHIBITION OF MITOCHONDRIAL BIOGENESIS IN SMALL-FOR-SIZE LIVER GRAFTS Transplantation. 86: 95. DOI: 10.1097/01.Tp.0000332527.17731.C4  0.465
2008 Zhong Z, Theruvath TP, Ramshesh VK, Rehman H, Lemasters JJ. 77. Intravital confocal/multiphoton imaging of liver function and injury after hepatic ischemia/reperfusion and liver transplantation Cryobiology. 57: 331. DOI: 10.1016/J.Cryobiol.2008.10.078  0.716
2008 Nieminen AL, Ramshesh VK, Lemasters JJ. Use of Fluorescent Reporters to Measure Mitochondrial Membrane Potential and the Mitochondrial Permeability Transition Drug-Induced Mitochondrial Dysfunction. 413-431. DOI: 10.1002/9780470372531.ch17  0.726
2007 Black D, Lyman S, Qian T, Lemasters JJ, Rippe RA, Nitta T, Kim JS, Behrns KE. Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species. Biochimie. 89: 1464-73. PMID 17936489 DOI: 10.1016/J.Biochi.2007.09.001  0.391
2007 Kon K, Ikejima K, Okumura K, Aoyama T, Arai K, Takei Y, Lemasters JJ, Sato N. Role of apoptosis in acetaminophen hepatotoxicity. Journal of Gastroenterology and Hepatology. 22: S49-52. PMID 17567465 DOI: 10.1111/J.1440-1746.2007.04962.X  0.482
2007 Lemasters JJ. Modulation of mitochondrial membrane permeability in pathogenesis, autophagy and control of metabolism. Journal of Gastroenterology and Hepatology. 22: S31-7. PMID 17567461 DOI: 10.1111/J.1440-1746.2006.04643.X  0.442
2007 Kim I, Rodriguez-Enriquez S, Lemasters JJ. Selective degradation of mitochondria by mitophagy. Archives of Biochemistry and Biophysics. 462: 245-53. PMID 17475204 DOI: 10.1016/J.Abb.2007.03.034  0.706
2007 Zhong Z, Theruvath TP, Currin RT, Waldmeier PC, Lemasters JJ. NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 1103-11. PMID 17456198 DOI: 10.1111/J.1600-6143.2007.01770.X  0.502
2007 Lemasters JJ, Ramshesh VK. Imaging of mitochondrial polarization and depolarization with cationic fluorophores. Methods in Cell Biology. 80: 283-95. PMID 17445700 DOI: 10.1016/S0091-679X(06)80014-2  0.732
2007 Conzelmann LO, Hines IN, Kremer M, Perry AW, Lemasters JJ, Wheeler MD. Extrahepatic cells contribute to the progenitor/stem cell response following reduced-size liver transplantation in mice. Experimental Biology and Medicine (Maywood, N.J.). 232: 571-80. PMID 17392494 DOI: 10.3181/00379727-232-2320571  0.367
2007 Hammond LE, Albright CD, He L, Rusyn I, Watkins SM, Doughman SD, Lemasters JJ, Coleman RA. Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice. Experimental and Molecular Pathology. 82: 210-9. PMID 17258706 DOI: 10.1016/J.Yexmp.2006.12.004  0.479
2007 Le SB, Hailer MK, Buhrow S, Wang Q, Flatten K, Pediaditakis P, Bible KC, Lewis LD, Sausville EA, Pang YP, Ames MM, Lemasters JJ, Holmuhamedov EL, Kaufmann SH. Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity. The Journal of Biological Chemistry. 282: 8860-72. PMID 17213201 DOI: 10.1074/Jbc.M611777200  0.435
2007 Lemasters JJ, Theruvath TP, Ramshesh VK, Zhong Z. Intravital Imaging of Liver Function: Moving Beyond Microcirculation The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a88-b  0.667
2006 Theruvath TP, Zhong Z, Currin RT, Ramshesh VK, Lemasters JJ. Endothelial nitric oxide synthase protects transplanted mouse livers against storage/reperfusion injury: Role of vasodilatory and innate immunity pathways. Transplantation Proceedings. 38: 3351-7. PMID 17175270 DOI: 10.1016/j.transproceed.2006.10.171  0.698
2006 Raval J, Lyman S, Nitta T, Mohuczy D, Lemasters JJ, Kim JS, Behrns KE. Basal reactive oxygen species determine the susceptibility to apoptosis in cirrhotic hepatocytes. Free Radical Biology & Medicine. 41: 1645-54. PMID 17145552 DOI: 10.1016/J.Freeradbiomed.2006.07.023  0.469
2006 Conzelmann LO, Lehnert M, Kremer M, Zhong Z, Wheeler MD, Lemasters JJ. Graft tumor necrosis factor receptor-1 protects after mouse liver transplantation whereas host tumor necrosis factor receptor-1 promotes injury. Transplantation. 82: 1214-20. PMID 17102774 DOI: 10.1097/01.Tp.0000239190.95190.5E  0.374
2006 Bajt ML, Cover C, Lemasters JJ, Jaeschke H. Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury. Toxicological Sciences : An Official Journal of the Society of Toxicology. 94: 217-25. PMID 16896059 DOI: 10.1093/Toxsci/Kfl077  0.432
2006 Rodriguez-Enriquez S, Kim I, Currin RT, Lemasters JJ. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy. 2: 39-46. PMID 16874071 DOI: 10.4161/Auto.2229  0.708
2006 Zhong Z, Schwabe RF, Kai Y, He L, Yang L, Bunzendahl H, Brenner DA, Lemasters JJ. Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. Transplantation. 82: 241-50. PMID 16858288 DOI: 10.1097/01.Tp.0000228867.98158.D2  0.318
2006 Lehmann TG, Luedde T, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA. Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 12: 550-9. PMID 16555330 DOI: 10.1002/Lt.20632  0.379
2006 Chimalakonda AP, Montgomery DL, Weidanz JA, Shaik IH, Nguyen JH, Lemasters JJ, Kobayashi E, Mehvar R. Attenuation of acute rejection in a rat liver transplantation model by a liver-targeted dextran prodrug of methylprednisolone. Transplantation. 81: 678-85. PMID 16534468 DOI: 10.1097/01.Tp.0000177654.48112.B6  0.376
2006 Malhi H, Gores GJ, Lemasters JJ. Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology (Baltimore, Md.). 43: S31-44. PMID 16447272 DOI: 10.1002/Hep.21062  0.446
2006 Kim JS, Jin Y, Lemasters JJ. Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2024-34. PMID 16399872 DOI: 10.1152/Ajpheart.00683.2005  0.401
2006 Vairetti M, Richelmi P, Bertè F, Currin RT, Lemasters JJ, Imberti R. Role of pH in protection by low sodium against hypoxic injury in isolated perfused rat livers. Journal of Hepatology. 44: 894-901. PMID 16313996 DOI: 10.1016/J.Jhep.2005.08.007  0.349
2006 Lemasters JJ, Holmuhamedov E. Voltage-dependent anion channel (VDAC) as mitochondrial governator--thinking outside the box. Biochimica Et Biophysica Acta. 1762: 181-90. PMID 16307870 DOI: 10.1016/J.Bbadis.2005.10.006  0.465
2006 Sheu SS, Lemasters JJ. Special issue: Mitochondria in diseases and therapeutics Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1762: 139. DOI: 10.1016/J.Bbadis.2005.11.003  0.305
2005 Zhong Z, Connor HD, Froh M, Bunzendahl H, Lind H, Lehnert M, Mason RP, Thurman RG, Lemasters JJ. Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology. 129: 652-64. PMID 16083719 DOI: 10.1053/J.Gastro.2005.05.060  0.335
2005 Cover C, Mansouri A, Knight TR, Bajt ML, Lemasters JJ, Pessayre D, Jaeschke H. Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity. The Journal of Pharmacology and Experimental Therapeutics. 315: 879-87. PMID 16081675 DOI: 10.1124/Jpet.105.088898  0.433
2005 Bustamante E, Pediaditakis P, He L, Lemasters JJ. Isolated mouse liver mitochondria are devoid of glucokinase. Biochemical and Biophysical Research Communications. 334: 907-10. PMID 16036222 DOI: 10.1016/J.Bbrc.2005.06.174  0.458
2005 He L, Lemasters JJ. Dephosphorylation of the Rieske iron-sulfur protein after induction of the mitochondrial permeability transition. Biochemical and Biophysical Research Communications. 334: 829-37. PMID 16023995 DOI: 10.1016/J.Bbrc.2005.06.170  0.437
2005 Lemasters JJ. Dying a thousand deaths: redundant pathways from different organelles to apoptosis and necrosis. Gastroenterology. 129: 351-60. PMID 16012960 DOI: 10.1053/J.Gastro.2005.06.006  0.359
2005 Lemasters JJ. Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuvenation Research. 8: 3-5. PMID 15798367 DOI: 10.1089/Rej.2005.8.3  0.423
2004 Zhong Z, Lemasters JJ. Role of free radicals in failure of fatty liver grafts caused by ethanol. Alcohol (Fayetteville, N.Y.). 34: 49-58. PMID 15670666 DOI: 10.1016/J.Alcohol.2004.08.006  0.352
2004 Kim JS, Ohshima S, Pediaditakis P, Lemasters JJ. Nitric oxide: a signaling molecule against mitochondrial permeability transition- and pH-dependent cell death after reperfusion. Free Radical Biology & Medicine. 37: 1943-50. PMID 15544914 DOI: 10.1016/J.Freeradbiomed.2004.09.014  0.48
2004 Kon K, Kim JS, Jaeschke H, Lemasters JJ. Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes. Hepatology (Baltimore, Md.). 40: 1170-9. PMID 15486922 DOI: 10.1002/Hep.20437  0.49
2004 Rodriguez-Enriquez S, He L, Lemasters JJ. Role of mitochondrial permeability transition pores in mitochondrial autophagy. The International Journal of Biochemistry & Cell Biology. 36: 2463-72. PMID 15325585 DOI: 10.1016/J.Biocel.2004.04.009  0.485
2004 Uehara T, Xi Peng X, Bennett B, Satoh Y, Friedman G, Currin R, Brenner DA, Lemasters J. c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation. Transplantation. 78: 324-32. PMID 15316358 DOI: 10.1097/01.Tp.0000128859.42696.28  0.347
2004 Kim JS, Ohshima S, Pediaditakis P, Lemasters JJ. Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition. Hepatology (Baltimore, Md.). 39: 1533-43. PMID 15185294 DOI: 10.1002/Hep.20197  0.525
2004 Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ, Brenner DA, Rippe RA, Behrns KE. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. Journal of Hepatology. 40: 942-51. PMID 15158334 DOI: 10.1016/J.Jhep.2004.02.031  0.345
2004 Bajt ML, Knight TR, Lemasters JJ, Jaeschke H. Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 343-9. PMID 15115886 DOI: 10.1093/Toxsci/Kfh151  0.364
2004 Zhong Z, Connor HD, Froh M, Lind H, Bunzendahl H, Mason RP, Thurman RG, Lemasters JJ. Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. Free Radical Biology & Medicine. 36: 1248-58. PMID 15110390 DOI: 10.1016/J.Freeradbiomed.2004.02.012  0.373
2004 Lemasters JJ. Rusty notions of cell injury. Journal of Hepatology. 40: 696-8. PMID 15030988 DOI: 10.1016/J.Jhep.2004.02.015  0.4
2004 Schwabe RF, Uchinami H, Qian T, Bennett BL, Lemasters JJ, Brenner DA. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 720-2. PMID 14766793 DOI: 10.1096/Fj.03-0771Fje  0.341
2004 Elmore SP, Nishimura Y, Qian T, Herman B, Lemasters JJ. Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Archives of Biochemistry and Biophysics. 422: 145-52. PMID 14759601 DOI: 10.1016/J.Abb.2003.12.031  0.797
2004 Conzelmann LO, Zhong Z, Lemasters JJ. RESPONSE TO “RECONSTRUCTION OF THE HEPATIC ARTERY IN LIVER TRANSPLANTATION IN MICE: MANDATORY OR USELESS?” Transplantation. 77: 1311-1312. DOI: 10.1097/01.Tp.0000122228.79061.50  0.322
2004 Sun J, Lemasters JJ, Zhong Z. INDUCIBLE AND ENDOTHELIAL NITRIC OXIDE SYNTHASE (INOS AND ENOS) DIFFERENTIALLY REGULATE LIVER REGENERATION AFTER PARTIAL HEPATECTOMY Transplantation. 78: 632. DOI: 10.1097/00007890-200407271-01701  0.334
2004 Zhong Z, Tsukada S, Rippe RA, Lemasters JJ. VIRAL DELIVERY OF THE SMAD7 GENE PREVENTS SUPPRESSION OF REGENERATION OF SMALL FOR–SIZE LIVER GRAFTS Transplantation. 78: 107. DOI: 10.1097/00007890-200407271-00287  0.311
2003 Bataller R, Schwabe RF, Choi YH, Yang L, Paik YH, Lindquist J, Qian T, Schoonhoven R, Hagedorn CH, Lemasters JJ, Brenner DA. NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. The Journal of Clinical Investigation. 112: 1383-94. PMID 14597764 DOI: 10.1172/Jci18212  0.33
2003 Kim JS, He L, Qian T, Lemasters JJ. Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes. Current Molecular Medicine. 3: 527-35. PMID 14527084 DOI: 10.2174/1566524033479564  0.475
2003 Jaeschke H, Lemasters JJ. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology. 125: 1246-57. PMID 14517806 DOI: 10.1016/S0016-5085(03)01209-5  0.462
2003 Zhao Y, Ding WX, Qian T, Watkins S, Lemasters JJ, Yin XM. Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology. 125: 854-67. PMID 12949730 DOI: 10.1016/S0016-5085(03)01066-7  0.437
2003 Conzelmann LO, Zhong Z, Bunzendahl H, Wheeler MD, Lemasters JJ. Reduced-size liver transplantation in the mouse. Transplantation. 76: 496-501. PMID 12923434 DOI: 10.1097/01.Tp.0000076469.93443.E4  0.348
2003 Waldmeier PC, Zimmermann K, Qian T, Tintelnot-Blomley M, Lemasters JJ. Cyclophilin D as a drug target. Current Medicinal Chemistry. 10: 1485-506. PMID 12871122 DOI: 10.2174/0929867033457160  0.341
2003 Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA, Thurman RG. Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation. 76: 28-37. PMID 12865782 DOI: 10.1097/01.Tp.0000065299.29900.17  0.371
2003 Kweon YO, Paik YH, Schnabl B, Qian T, Lemasters JJ, Brenner DA. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. Journal of Hepatology. 39: 38-46. PMID 12821042 DOI: 10.1016/S0168-8278(03)00178-8  0.391
2003 Zhong Z, Froh M, Lehnert M, Schoonhoven R, Yang L, Lind H, Lemasters JJ, Thurman RG. Polyphenols from Camellia sinenesis attenuate experimental cholestasis-induced liver fibrosis in rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G1004-13. PMID 12791596 DOI: 10.1152/Ajpgi.00008.2003  0.378
2003 Kim JS, He L, Lemasters JJ. Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochemical and Biophysical Research Communications. 304: 463-70. PMID 12729580 DOI: 10.1016/S0006-291X(03)00618-1  0.466
2003 Oh KW, Qian T, Brenner DA, Lemasters JJ. Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicological Sciences : An Official Journal of the Society of Toxicology. 73: 44-52. PMID 12700412 DOI: 10.1093/Toxsci/Kfg045  0.396
2003 Lehnert M, Arteel GE, Smutney OM, Conzelmann LO, Zhong Z, Thurman RG, Lemasters JJ. Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide. Shock (Augusta, Ga.). 19: 345-51. PMID 12688546 DOI: 10.1097/00024382-200304000-00009  0.35
2003 He L, Lemasters JJ. Heat shock suppresses the permeability transition in rat liver mitochondria. The Journal of Biological Chemistry. 278: 16755-60. PMID 12611884 DOI: 10.1074/Jbc.M300153200  0.379
2003 Kim JS, Qian T, Lemasters JJ. Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology. 124: 494-503. PMID 12557154 DOI: 10.1053/Gast.2003.50059  0.435
2003 KON K, KIM J, DOYAL E, LEMASTERS J. 237 Role of the mitochondrial permeability transition in acetaminophen-induced necrotic and apoptotic cell death to cultured mouse hepatocytes Hepatology. 38: 271-271. DOI: 10.1016/S0270-9139(03)80280-X  0.451
2002 Lemasters JJ, Qian T, He L, Kim JS, Elmore SP, Cascio WE, Brenner DA. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxidants & Redox Signaling. 4: 769-81. PMID 12470504 DOI: 10.1089/152308602760598918  0.829
2002 Zhong Z, Froh M, Connor HD, Li X, Conzelmann LO, Mason RP, Lemasters JJ, Thurman RG. Prevention of hepatic ischemia-reperfusion injury by green tea extract. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G957-64. PMID 12223356 DOI: 10.1152/Ajpgi.00216.2001  0.373
2002 Yin M, Currin RT, Peng XX, Mekeel HE, Schoonhoven R, Lemasters JJ. Different patterns of renal cell killing after warm and cold ischemia. Renal Failure. 24: 147-63. PMID 12071589 DOI: 10.1081/Jdi-120004092  0.332
2002 Waldmeier PC, Feldtrauer JJ, Qian T, Lemasters JJ. Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811. Molecular Pharmacology. 62: 22-9. PMID 12065751 DOI: 10.1124/Mol.62.1.22  0.484
2002 He L, Lemasters JJ. Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? Febs Letters. 512: 1-7. PMID 11852041 DOI: 10.1016/S0014-5793(01)03314-2  0.408
2002 Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Mechanisms of hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 166-76. PMID 11812920 DOI: 10.1093/Toxsci/65.2.166  0.508
2002 Lehnert M, Arteel GE, Conzelmann LO, Zhong Z, Thurman RG, Lemasters JJ, Marzi I. NADPH OXIDASE DERIVED SUPEROXIDE IS A KEY REGULATOR OF LIVER INJURY AFTER HEMORRHAGIC SHOCK AND RESUSCITATION. Shock. 17: 22. DOI: 10.1097/00024382-200206001-00064  0.361
2002 Lemasters JJ. RONALD G. THURMAN (1941-2001) Alcohol and Alcoholism. 37: 624-625. DOI: 10.1093/Alcalc/37.6.624  0.304
2002 Kim Y, Schwabe RF, Qian T, Lemasters JJ, Brenner DA. TRAIL-mediated apoptosis requires NF-kB inhibition and the mitochondrial permeability transition in human hepatoma cells Hepatology. 36: 1498-1508. DOI: 10.1002/Hep.1840360627  0.341
2001 Nishimura Y, Lemasters JJ. Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia. Cell Death and Differentiation. 8: 850-8. PMID 11526438 DOI: 10.1038/Sj.Cdd.4400877  0.316
2001 Elmore SP, Qian T, Grissom SF, Lemasters JJ. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2286-7. PMID 11511528 DOI: 10.1096/Fj.01-0206Fje  0.823
2001 Blattner JR, He L, Lemasters JJ. Screening assays for the mitochondrial permeability transition using a fluorescence multiwell plate reader. Analytical Biochemistry. 295: 220-6. PMID 11488625 DOI: 10.1006/Abio.2001.5219  0.775
2001 Schemmer P, Enomoto N, Bradford BU, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG. Activated Kupffer cells cause a hypermetabolic state after gentle in situ manipulation of liver in rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G1076-82. PMID 11352799 DOI: 10.1152/Ajpgi.2001.280.6.G1076  0.391
2001 Arai M, Thurman RG, Lemasters JJ. Ischemic preconditioning of rat livers against cold storage-reperfusion injury: role of nonparenchymal cells and the phenomenon of heterologous preconditioning. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 7: 292-9. PMID 11303287 DOI: 10.1053/Jlts.2001.23080  0.409
2001 Hunt KJ, Lemasters JJ, Thurman RG. High concentrations of adenosine are needed in Carolina rinse to prevent activation of Kupffer cells. Transplant International : Official Journal of the European Society For Organ Transplantation. S493-5. PMID 11271289 DOI: 10.1111/J.1432-2277.1994.Tb01427.X  0.356
2001 Savier E, Lemasters JJ, Thurman RG. Kupffer cells participate in rejection following liver transplantation in the rat. Transplant International : Official Journal of the European Society For Organ Transplantation. S183-6. PMID 11271199 DOI: 10.1111/J.1432-2277.1994.Tb01343.X  0.358
2001 Huynh T, Lemasters JJ, Bracey LW, Baker CC. Proinflammatory kupffer cell alterations after femur fracture trauma and sepsis in rats. Shock (Augusta, Ga.). 14: 555-60. PMID 11092689 DOI: 10.1097/00024382-200014050-00010  0.309
2001 Qian T, Lemasters JJ. Accelerated Mitochondrial Reactive Oxygen Species Formation Induces OnsẸt of the Mitochondrial Permeability Transition and Mitochondrial Swelling in Cultured Hepatocytes After TNFα Exposure Microscopy and Microanalysis. 7: 604-605. DOI: 10.1017/S1431927600029093  0.449
2000 Oh KW, Currin RT, Lemasters JJ. Kupffer cells mediate increased anoxic hepatocellular killing from hyperosmolarity by an oxygen- and prostaglandin-independent mechanism Toxicology Letters. 117: 95-100. PMID 11033238 DOI: 10.1016/S0378-4274(00)00247-2  0.391
2000 Arai M, Thurman RG, Lemasters JJ. Contribution of adenosine A(2) receptors and cyclic adenosine monophosphate to protective ischemic preconditioning of sinusoidal endothelial cells against Storage/Reperfusion injury in rat livers. Hepatology (Baltimore, Md.). 32: 297-302. PMID 10915736 DOI: 10.1053/Jhep.2000.8896  0.363
2000 Trollinger DR, Cascio WE, Lemasters JJ. Mitochondrial calcium transients in adult rabbit cardiac myocytes: inhibition by ruthenium red and artifacts caused by lysosomal loading of Ca(2+)-indicating fluorophores. Biophysical Journal. 79: 39-50. PMID 10866936 DOI: 10.1016/S0006-3495(00)76272-2  0.435
2000 Hatano E, Bradham CA, Stark A, Iimuro Y, Lemasters JJ, Brenner DA. The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes Journal of Biological Chemistry. 275: 11814-11823. PMID 10766806 DOI: 10.1074/Jbc.275.16.11814  0.367
2000 Lemasters JJ. The mitochondrial permeability transition and the calcium, oxygen and pH paradoxes: one paradox after another. Cardiovascular Research. 44: 470-3. PMID 10690277 DOI: 10.1016/S0008-6363(99)00368-5  0.393
2000 Zhang Y, Lemasters J, Herman B. Localization of Rat Liver Group IIA Phospholipase A(2) in Secretory Pathways: Green Fluorescent Protein Approach. Microscopy and Microanalysis. 6: 150-155. DOI: 10.1017/S1431927600033249  0.386
1999 Lemasters JJ, Trollinger DR, Qian T, Cascio WE, Ohata H. Confocal imaging of Ca2+, pH, electrical potential, and membrane permeability in single living cells. Methods in Enzymology. 302: 341-58. PMID 12876784 DOI: 10.1016/S0076-6879(99)02031-5  0.315
1999 Lemasters JJ, Qian T, Trost LC, Herman B, Cascio WE, Bradham CA, Brenner DA, Nieminen AL. Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death. Biochemical Society Symposium. 66: 205-22. PMID 10989668 DOI: 10.1042/Bss0660205  0.518
1999 Lemasters JJ, Qian T, Bradham CA, Brenner DA, Cascio WE, Trost LC, Nishimura Y, Nieminen AL, Herman B. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. Journal of Bioenergetics and Biomembranes. 31: 305-19. PMID 10665521 DOI: 10.1023/A:1005419617371  0.516
1999 Schemmer P, Schoonhoven R, Swenberg JA, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG. Gentle organ manipulation during harvest as a key determinant of survival of fatty livers after transplantation in the rat. Transplant International : Official Journal of the European Society For Organ Transplantation. 12: 351-9. PMID 10552001 DOI: 10.1007/S001470050239  0.373
1999 Arai M, Peng XX, Currin RT, Thurman RG, Lemasters JJ. Protection of sinusoidal endothelial cells against storage/reperfusion injury by prostaglandin E2 derived from Kupffer cells. Transplantation. 68: 440-5. PMID 10459549 DOI: 10.1097/00007890-199908150-00017  0.347
1999 v Frankenberg M, Stachlewitz RF, Forman DT, Frey W, Bunzendahl H, Lemasters JJ, Thurman RG. Amino acids in rinse effluents as a predictor of graft function after transplantation of fatty livers in rats. Transplant International : Official Journal of the European Society For Organ Transplantation. 12: 168-75. PMID 10429953 DOI: 10.1007/S001470050206  0.33
1999 Lichtman SN, Lemasters JJ. Role of cytokines and cytokine-producing cells in reperfusion injury to the liver. Seminars in Liver Disease. 19: 171-87. PMID 10422199 DOI: 10.1055/S-2007-1007108  0.326
1999 Byrne AM, Lemasters JJ, Nieminen AL. Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes. Hepatology (Baltimore, Md.). 29: 1523-31. PMID 10216138 DOI: 10.1002/Hep.510290521  0.47
1999 Schemmer P, Bradford BU, Rose ML, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG. Intravenous glycine improves survival in rat liver transplantation. The American Journal of Physiology. 276: G924-32. PMID 10198336 DOI: 10.1152/Ajpgi.1999.276.4.G924  0.386
1999 Qian T, Herman B, Lemasters JJ. The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicology and Applied Pharmacology. 154: 117-25. PMID 9925795 DOI: 10.1006/Taap.1998.8580  0.445
1999 Lemasters JJ. V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. The American Journal of Physiology. 276: G1-6. PMID 9886971 DOI: 10.1152/Ajpgi.1999.276.1.G1  0.441
1999 Zhong Z, Connor HD, Mason RP, Lemasters JJ, Thurman RG. Ethanol, not fat accumulation per se, increases free radical production in a low-flow, reflow liver perfusion model. Transplantation. 66: 1431-8. PMID 9869083 DOI: 10.1097/00007890-199812150-00005  0.333
1999 Qian T, Trost LC, Lemasters JJ. Quenching or Misalignment? Confocal Microscopy Onset of the Mitochondrial Permeability Transition in Cultured Hepatocytes Microscopy and Microanalysis. 5: 468-469. DOI: 10.1017/S143192760001566X  0.414
1998 Lemasters JJ, Qian T, Elmore SP, Trost LC, Nishimura Y, Herman B, Bradham CA, Brenner DA, Nieminen AL. Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy. Biofactors (Oxford, England). 8: 283-5. PMID 9914830 DOI: 10.1002/Biof.5520080316  0.828
1998 Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA, Lemasters JJ. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Molecular and Cellular Biology. 18: 6353-64. PMID 9774651 DOI: 10.1128/Mcb.18.11.6353  0.441
1998 Lemasters JJ. The mitochondrial permeability transition: from biochemical curiosity to pathophysiological mechanism. Gastroenterology. 115: 783-6. PMID 9742002 DOI: 10.1016/S0016-5085(98)70160-X  0.417
1998 Ohata H, Chacon E, Tesfai SA, Harper IS, Herman B, Lemasters JJ. Mitochondrial Ca2+ transients in cardiac myocytes during the excitation-contraction cycle: effects of pacing and hormonal stimulation. Journal of Bioenergetics and Biomembranes. 30: 207-22. PMID 9733088 DOI: 10.1023/A:1020588618496  0.406
1998 Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA, Brenner DA, Herman B. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochimica Et Biophysica Acta. 1366: 177-96. PMID 9714796 DOI: 10.1016/S0005-2728(98)00112-1  0.833
1998 Nishimura Y, Romer LH, Lemasters JJ. Mitochondrial dysfunction and cytoskeletal disruption during chemical hypoxia to cultured rat hepatic sinusoidal endothelial cells: the pH paradox and cytoprotection by glucose, acidotic pH, and glycine. Hepatology (Baltimore, Md.). 27: 1039-49. PMID 9537444 DOI: 10.1002/Hep.510270420  0.385
1998 Trost LC, Lemasters JJ. Role of the mitochondrial permeability transition in salicylate toxicity to cultured rat hepatocytes: implications for the pathogenesis of Reye's syndrome. Toxicology and Applied Pharmacology. 147: 431-41. PMID 9439738 DOI: 10.1006/Taap.1997.8313  0.46
1998 Trollinger DR, Cascio WE, Lemasters JJ. Confocal Imaging of Both Mitochondrial and Cytosolic Free Ca2+ in Cardiac Myocytes Co-Loaded with Rhod 2 and Fluo 3: Inhibition by Ruthenium Red of Mitochondrial but not Cytosolic Ca2+ Transients Microscopy and Microanalysis. 4: 448-449. DOI: 10.1017/S1431927600022364  0.396
1998 Bradham C, Qian T, Streetz K, Lemasters J, Brenner D. The mitochondrial permeability transition is downstream from fadd and caspase 1-like proteases, and upstream from caspase 3-like proteases during TNFα-mediated apoptosis in hepatocytes Gastroenterology. 114: A1214. DOI: 10.1016/S0016-5085(98)84927-5  0.42
1997 Qian T, Nieminen AL, Herman B, Lemasters JJ. Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes. The American Journal of Physiology. 273: C1783-92. PMID 9435481 DOI: 10.1152/Ajpcell.1997.273.6.C1783  0.372
1997 Zhong Z, Connor H, Stachlewitz RF, Frankenberg M, Mason RP, Lemasters JJ, Thurman RG. Role of free radicals in primary nonfunction of marginal fatty grafts from rats treated acutely with ethanol. Molecular Pharmacology. 52: 912-9. PMID 9351983 DOI: 10.1124/Mol.52.5.912  0.328
1997 Zhong Z, Connor H, Mason RP, Qu W, Stachlewitz RF, Gao W, Lemasters JJ, Thurman RG. Destruction of Kupffer cells increases survival and reduces graft injury after transplantation of fatty livers from ethanol-treated rats. Liver Transplantation and Surgery : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 2: 383-7. PMID 9346680 DOI: 10.1002/Lt.500020509  0.36
1997 Lemasters JJ, Bunzendahl H, Thurman RG. Reperfusion injury to donor livers stored for transplantation. Liver Transplantation and Surgery : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 1: 124-38. PMID 9346554 DOI: 10.1002/Lt.500010211  0.346
1997 Lemasters JJ, Nieminen AL. Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes. Bioscience Reports. 17: 281-91. PMID 9337483 DOI: 10.1023/A:1027332611839  0.452
1997 Trollinger DR, Cascio WE, Lemasters JJ. Selective loading of Rhod 2 into mitochondria shows mitochondrial Ca2+ transients during the contractile cycle in adult rabbit cardiac myocytes. Biochemical and Biophysical Research Communications. 236: 738-42. PMID 9245725 DOI: 10.1006/Bbrc.1997.7042  0.433
1997 Nieminen AL, Byrne AM, Herman B, Lemasters JJ. Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species. The American Journal of Physiology. 272: C1286-94. PMID 9142854 DOI: 10.1152/ajpcell.1997.272.4.C1286  0.359
1997 Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadev S, Jenkins G, Hannun Y, Lemasters JJ, Thurman RG, Brenner DA. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology (Baltimore, Md.). 25: 1128-35. PMID 9141429 DOI: 10.1002/Hep.510250514  0.366
1997 Lemasters JJ, Thurman RG. Reperfusion injury after liver preservation for transplantation. Annual Review of Pharmacology and Toxicology. 37: 327-38. PMID 9131256 DOI: 10.1146/Annurev.Pharmtox.37.1.327  0.381
1997 Currin RT, Caldwell-Kenkel JC, Lichtman SN, Bachmann S, Takei Y, Kawano S, Thurman RG, Lemasters JJ. Protection by Carolina rinse solution, acidotic pH, and glycine against lethal reperfusion injury to sinusoidal endothelial cells of rat livers stored for transplantation. Transplantation. 62: 1549-58. PMID 8970606 DOI: 10.1097/00007890-199612150-00004  0.386
1997 Nieminen AL, Petrie TG, Lemasters JJ, Selman WR. Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: evidence of the mitochondrial permeability transition. Neuroscience. 75: 993-7. PMID 8938735 DOI: 10.1016/0306-4522(96)00378-8  0.314
1997 Thurman RG, Gao W, Connor HD, Adachi Y, Stachlewitz RF, Zhong Z, Knecht KT, Bradford BU, Mason RP, Lemasters JJ. Role of free radicals in failure of fatty livers following liver transplantation and alcoholic liver injury. Advances in Experimental Medicine and Biology. 387: 231-41. PMID 8794217 DOI: 10.1007/978-1-4757-9480-9_31  0.389
1997 Lemasters JJ, Nieminen A, Qian T, Trost LC, Herman B. Molecular and Cellular Biochemistry. 174: 159-165. DOI: 10.1023/A:1006827601337  0.504
1997 Wang H, Harrison-Shostak DC, Wang XF, Nieminen AL, Lemasters JJ, Herman B. Role of phospholipid catabolism in hypoxic and ischemic injury Advances in Lipobiology. 2: 167-194. DOI: 10.1016/S1874-5245(97)80009-2  0.32
1996 Wang H, Harrison-Shostak DC, Lemasters JJ, Herman B. Contribution of pH-dependent group II phospholipase A2 to chemical hypoxic injury in rat hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1319-25. PMID 8836046 DOI: 10.1096/Fasebj.10.11.8836046  0.338
1996 Chacon E, Ohata H, Harper IS, Trollinger DR, Herman B, Lemasters JJ. Mitochondrial free calcium transients during excitation-contraction coupling in rabbit cardiac myocytes. Febs Letters. 382: 31-6. PMID 8612759 DOI: 10.1016/0014-5793(96)00138-X  0.442
1996 Lemasters JJ, Peng XX, Bachmann S, Currin RT, Gao W, Thurman RG. Dual role of Kupffer cell activation and endothelial cell damage in reperfusion injury to livers stored for transplantation surgery. Journal of Gastroenterology and Hepatology. S84-7. PMID 8589353 DOI: 10.1111/J.1440-1746.1995.Tb01808.X  0.403
1995 Lemasters JJ, Chacon E, Ohata H, Harper IS, Nieminen AL, Tesfai SA, Herman B. Measurement of electrical potential, pH, and free calcium ion concentration in mitochondria of living cells by laser scanning confocal microscopy. Methods in Enzymology. 260: 428-44. PMID 8592465 DOI: 10.1016/0076-6879(95)60156-2  0.389
1995 Gao W, Connor HD, Lemasters JJ, Mason RP, Thurman RG. Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species. Transplantation. 59: 674-9. PMID 7886790 DOI: 10.1097/00007890-199503150-00005  0.345
1995 Caldwell-Kenkel JC, Currin RT, Coote A, Thurman RG, Lemasters JJ. Reperfusion injury to endothelial cells after cold storage of rat livers: protection by mildly acidic pH and lack of protection by antioxidants. Transplant International : Official Journal of the European Society For Organ Transplantation. 8: 77-85. PMID 7766302 DOI: 10.1007/Bf00344415  0.413
1995 Nieminen AL, Saylor AK, Tesfai SA, Herman B, Lemasters JJ. Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. The Biochemical Journal. 307: 99-106. PMID 7718000 DOI: 10.1042/bj3070099  0.404
1995 PENG X, CURRIN RT, THURMAN RG, LEMASTERS JJ. PROTECTION BY PENTOXIFYLLINE AGAINST NORMOTHERMIC LIVER ISCHEMIA/REPERFUSION IN RATS Transplantation. 59: 1537-1541. DOI: 10.1097/00007890-199506000-00006  0.394
1995 Kaplan SH, Yang H, Gilliam DE, Shen J, Lemasters JJ, Cascio WE. Hypercapnic acidosis and dimethyl amiloride reduce reperfusion induced cell death in ischaemic ventricular myocardium Cardiovascular Research. 29: 231-238. DOI: 10.1016/S0008-6363(96)88575-0  0.326
1995 Zahrebelski G, Nieminen A, Al-Ghoul K, Qian T, Herman B, Lemasters JJ. Progression of subcellular changes during chemical hypoxia to cultured rat hepatocytes: A laser scanning confocal microscopic study Hepatology. 21: 1361-1372. DOI: 10.1002/Hep.1840210521  0.446
1994 Nieminen AL, Saylor AK, Herman B, Lemasters JJ. ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition. The American Journal of Physiology. 267: C67-74. PMID 8048493 DOI: 10.1152/ajpcell.1994.267.1.C67  0.403
1994 Chacon E, Reece JM, Nieminen AL, Zahrebelski G, Herman B, Lemasters JJ. Distribution of electrical potential, pH, free Ca2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia: A multiparameter digitized confocal microscopic study Biophysical Journal. 66: 942-952. PMID 8038398 DOI: 10.1016/S0006-3495(94)80904-X  0.336
1994 Fusaoka T, Hunt KJ, Lemasters JJ, Thurman RG. EVIDENCE THAT ACTIVATION OF KUPFFER CELLS INCREASES OXYGEN UPTAKE AFTER COLD STORAGE Transplantation. 58: 1067-1071. DOI: 10.1097/00007890-199411000-00002  0.374
1994 Reinstein LJ, Lichtman SN, Currin RT, Wang J, Thurman RG, Lemasters JJ. Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: Evidence for A2 receptors on rat kupffer cells Hepatology. 19: 1445-1452. DOI: 10.1002/Hep.1840190620  0.309
1993 Thurman RG, Bunzendahl H, Lemasters JJ. Role of sinusoidal lining cells in hepatic reperfusion injury following cold storage and transplantation. Seminars in Liver Disease. 13: 93-100. PMID 8446911 DOI: 10.1055/S-2007-1007341  0.334
1993 Gao W, Lemasters JJ, Thurman RG. Development of a new method for hepatic rearterialization in rat orthotopic liver transplantation. Reduction of liver injury and improvement of surgical outcome by arterialization. Transplantation. 56: 19-24. PMID 8333041 DOI: 10.1097/00007890-199307000-00004  0.366
1992 Marzi I, Cowper K, Takei Y, Lindert K, Lemasters JJ, Thurman RG. Methyl palmitate prevents Kupffer cell activation and improves survival after orthotopic liver transplantation in the rat. Transplant International : Official Journal of the European Society For Organ Transplantation. 4: 215-20. PMID 1786059 DOI: 10.1007/Bf00649106  0.375
1992 Gao WS, Hijioka T, Lindert KA, Caldwell-Kenkel JC, Lemasters JJ, Thurman RG. Evidence that adenosine is a key component in Carolina rinse responsible for reducing graft failure after orthotopic liver transplantation in the rat. Transplantation. 52: 992-8. PMID 1750086 DOI: 10.1097/00007890-199112000-00011  0.377
1992 Nieminen AL, Gores GJ, Bond JM, Imberti R, Herman B, Lemasters JJ. A novel cytotoxicity screening assay using a multiwell fluorescence scanner. Toxicology and Applied Pharmacology. 115: 147-55. PMID 1641848 DOI: 10.1016/0041-008X(92)90317-L  0.353
1992 Bachmann S, Caldwell-Kenkel JC, Oleksy I, Steffen R, Thurman RG, Lemasters JJ. Warm Carolina rinse solution prevents graft failure from storage injury after orthotopic rat liver transplantation with arterialization. Transplant International : Official Journal of the European Society For Organ Transplantation. 5: 108-14. PMID 1627236 DOI: 10.1007/Bf00339225  0.343
1992 Yamanaka H, Nukina S, Handler JA, Currin RT, Lemasters JJ, Thurman RG. Transient activation of hepatic glycogenolysis by thrombin in perfused rat livers. European Journal of Biochemistry. 208: 753-9. PMID 1396679 DOI: 10.1111/J.1432-1033.1992.Tb17244.X  0.37
1992 Connor HD, Gao W, Nukina S, Lemasters JJ, Mason RP, Thurman RG. Evidence that free radicals are involved in graft failure following orthotopic liver transplantation in the rat--an electron paramagnetic resonance spin trapping study. Transplantation. 54: 199-204. PMID 1323148 DOI: 10.1097/00007890-199208000-00002  0.323
1991 Herman B, Gores GJ, Nieminen AL, Kawanishi T, Harman A, Lemasters JJ. Calcium and pH in anoxic and toxic injury. Critical Reviews in Toxicology. 21: 127-48. PMID 2083032 DOI: 10.3109/10408449009089876  0.414
1991 Florine-Casteel K, Lemasters JJ, Herman B. Lipid order in hepatocyte plasma membrane blebs during ATP depletion measured by digitized video fluorescence polarization microscopy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2078-84. PMID 2010060 DOI: 10.1096/Fasebj.5.7.2010060  0.321
1991 Currin RT, Gores GJ, Thurman RG, Lemasters JJ. Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 207-10. PMID 2004664 DOI: 10.1096/Fasebj.5.2.2004664  0.338
1991 Lemasters JJ, Thurman RG. Reperfusion injury: a role for neutrophils. Hepatology (Baltimore, Md.). 14: 954-5. PMID 1937402 DOI: 10.1002/Hep.1840140533  0.373
1991 Harrison DC, Lemasters JJ, Herman B. A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes. Biochemical and Biophysical Research Communications. 174: 654-9. PMID 1899571 DOI: 10.1016/0006-291X(91)91467-Q  0.326
1991 Gao WS, Takei Y, Marzi I, Lindert KA, Caldwell-Kenkel JC, Currin RT, Tanaka Y, Lemasters JJ, Thurman RG. Carolina rinse solution--a new strategy to increase survival time after orthotopic liver transplantation in the rat. Transplantation. 52: 417-24. PMID 1897011 DOI: 10.1097/00007890-199109000-00005  0.362
1991 Takei Y, Gao WS, Hijioka T, Savier E, Lindert KA, Lemasters JJ, Thurman RG. Increase in survival of liver grafts after rinsing with warm Ringer's solution due to improvement of hepatic microcirculation. Transplantation. 52: 225-30. PMID 1871793 DOI: 10.1097/00007890-199108000-00008  0.387
1991 te Koppele JM, Keller BJ, Caldwell-Kenkel JC, Lemasters JJ, Thurman RG. Effect of hepatotoxic chemicals and hypoxia on hepatic nonparenchymal cells: impairment of phagocytosis by Kupffer cells and disruption of the endothelium in rat livers perfused with colloidal carbon. Toxicology and Applied Pharmacology. 110: 20-30. PMID 1871771 DOI: 10.1016/0041-008X(91)90286-N  0.37
1991 Ganey PE, Keller B, Lichtman SN, Lemasters JJ, Thurman RG. A new method to monitor Kupffer cell phagocytosis continuously in perfused rat liver Hepatology. 13: 567-574. DOI: 10.1002/Hep.1840130327  0.391
1991 Caldwell-Kenkel JC, Currin RT, Tanaka Y, Thurman RG, Lemasters JJ. Kupffer cell activation and endothelial cell damage after storage of rat livers: Effects of reperfusion Hepatology. 13: 83-95. DOI: 10.1002/Hep.1840130113  0.391
1990 Kost LJ, Gores GJ, Sayles JM, Miller LJ, Lemasters JJ, Herman B, LaRusso NF. Lack of metabolic effects of cholecystokinin on hepatocytes. Hepatology (Baltimore, Md.). 12: 301-5. PMID 2391069 DOI: 10.1002/Hep.1840120218  0.312
1990 Harman AW, Nieminen AL, Lemasters JJ, Herman B. Cytosolic free magnesium, ATP and blebbing during chemical hypoxia in cultured rat hepatocytes. Biochemical and Biophysical Research Communications. 170: 477-83. PMID 2383254 DOI: 10.1016/0006-291X(90)92116-H  0.351
1990 Takei Y, Marzi I, Kauffman FC, Currin RT, Lemasters JJ, Thurman RG. Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker, nisoldipine1 Transplantation. 50: 14-20. PMID 2368133 DOI: 10.1097/00007890-199007000-00003  0.378
1990 Nieminen AL, Dawson TL, Gores GJ, Kawanishi T, Herman B, Lemasters JJ. Protection by acidotic pH and fructose against lethal injury to rat hepatocytes from mitochondrial inhibitors, ionophores and oxidant chemicals. Biochemical and Biophysical Research Communications. 167: 600-6. PMID 2322245 DOI: 10.1016/0006-291X(90)92067-A  0.427
1990 Roe MW, Lemasters JJ, Herman B. Assessment of Fura-2 for measurements of cytosolic free calcium. Cell Calcium. 11: 63-73. PMID 2191782 DOI: 10.1016/0143-4160(90)90060-8  0.317
1990 Lemasters JJ, Gores GJ, Nieminen AL, Dawson TL, Wray BE, Herman B. Multiparameter digitized video microscopy of toxic and hypoxic injury in single cells. Environmental Health Perspectives. 84: 83-94. PMID 2190822 DOI: 10.1289/Ehp.908483  0.413
1989 Nieminen AL, Gores GJ, Wray BE, Tanaka Y, Herman B, Lemasters JJ. Calcium dependence of bleb formation and cell death in hepatocytes. Cell Calcium. 9: 237-46. PMID 3224370 DOI: 10.1016/0143-4160(88)90004-8  0.344
1989 Thurman RG, Lemasters JJ. New micro-optical methods to study metabolism in periportal and pericentral regions of the liver lobule. Drug Metabolism Reviews. 19: 263-81. PMID 3068031 DOI: 10.3109/03602538808994136  0.326
1989 Marzi I, Zhong Z, Lemasters JJ, Thurman RG. Evidence that graft survival is not related to parenchymal cell viability in rat liver transplantation. The importance of nonparenchymal cells. Transplantation. 48: 463-8. PMID 2675407 DOI: 10.1097/00007890-198909000-00023  0.407
1989 Caldwell-Kenkel JC, Currin RT, Tanaka Y, Thurman RG, Lemasters JJ. Reperfusion injury to endothelial cells following cold ischemic storage of rat livers. Hepatology (Baltimore, Md.). 10: 292-9. PMID 2668147 DOI: 10.1002/Hep.1840100307  0.302
1989 Gores GJ, Nieminen AL, Wray BE, Herman B, Lemasters JJ. Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death. The Journal of Clinical Investigation. 83: 386-96. PMID 2536397 DOI: 10.1172/Jci113896  0.382
1989 Thurman RG, Apel ED, Lemasters JJ. Protective effect of nitrendipine against hypoxic injury in perfused livers from ethanol-treated rats. Journal of Cardiovascular Pharmacology. S113-6. PMID 2468851 DOI: 10.1097/00005344-198806124-00024  0.392
1988 Gores GJ, Nieminen AL, Fleishman KE, Dawson TL, Herman B, Lemasters JJ. Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. The American Journal of Physiology. 255: C315-22. PMID 3421314 DOI: 10.1152/Ajpcell.1988.255.3.C315  0.358
1988 Marotto ME, Thurman RG, Lemasters JJ. Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: protection by allopurinol. Hepatology (Baltimore, Md.). 8: 585-90. PMID 3371875 DOI: 10.1002/Hep.1840080325  0.382
1988 Herman B, Nieminen AL, Gores GJ, Lemasters JJ. Irreversible injury in anoxic hepatocytes precipitated by an abrupt increase in plasma membrane permeability. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 146-51. PMID 3342967 DOI: 10.1096/Fasebj.2.2.3342967  0.301
1988 Thurman RG, Marzi I, Seitz G, Thies J, Lemasters JJ, Zimmerman F. Hepatic reperfusion injury following orthotopic liver transplantation in the rat. Transplantation. 46: 502-6. PMID 3051556 DOI: 10.1097/00007890-198810000-00006  0.409
1988 Stine KE, Reiter LW, Lemasters JJ. Alkyltin inhibition of ATPase activities in tissue homogenates and subcellular fractions from adult and neonatal rats Toxicology and Applied Pharmacology. 94: 394-406. PMID 2969635 DOI: 10.1016/0041-008X(88)90280-3  0.359
1987 Anundi I, King J, Owen DA, Schneider H, Lemasters JJ, Thurman RG. Fructose prevents hypoxic cell death in liver. The American Journal of Physiology. 253: G390-6. PMID 3631273 DOI: 10.1152/Ajpgi.1987.253.3.G390  0.394
1987 Lemasters JJ, DiGuiseppi J, Nieminen AL, Herman B. Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes. Nature. 325: 78-81. PMID 3099216 DOI: 10.1038/325078A0  0.407
1987 Lemasters JJ, Fleishman KE. An ATP/2e-stoichiometry of 1 1/2 is thermodynamically possible for site 3 of oxidative phosphorylation. Biochemical and Biophysical Research Communications. 142: 176-82. PMID 3028400 DOI: 10.1016/0006-291X(87)90467-0  0.306
1987 Thurman RG, King JN, Lemasters JJ. Nitrendipine Protects the Liver Against Hypoxia-Induced Damage at Submicromolar Concentrations in the Perfused Rat Liver Journal of Cardiovascular Pharmacology. 9: S71-S76. DOI: 10.1097/00005344-198700094-00012  0.377
1986 Emaus RK, Grunwald R, Lemasters JJ. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochimica Et Biophysica Acta. 850: 436-48. PMID 2873836 DOI: 10.1016/0005-2728(86)90112-X  0.458
1984 Thurman RG, Ji S, Matsumura T, Lemasters JJ. Is hypoxia involved in the mechanism of alcohol-induced liver injury? Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: 125-33. PMID 6724187 DOI: 10.1016/0272-0590(84)90112-X  0.38
1984 Freedman JA, Lemasters JJ. Thermodynamics of reverse electron transfer across site 1: ATP/2e- is greater than one. Biochemical and Biophysical Research Communications. 125: 8-13. PMID 6508810 DOI: 10.1016/S0006-291X(84)80325-3  0.316
1983 Ji S, Lemasters JJ, Christenson V, Thurman RG. Selective increase in pericentral oxygen gradient in perfused rat liver following ethanol treatment. Pharmacology, Biochemistry, and Behavior. 18: 439-42. PMID 6685302 DOI: 10.1016/0091-3057(83)90214-9  0.337
1983 Lemasters JJ, Ji S, Stemkowski CJ, Thurman RG. Hypoxic hepatocellular injury. Pharmacology, Biochemistry, and Behavior. 455-9. PMID 6634855 DOI: 10.1016/0091-3057(83)90217-4  0.376
1983 Belinsky SA, Kauffman FC, Ji S, Lemasters JJ, Thurman RG. Stimulation of mixed-function oxidation of 7-ethoxycoumarin in periportal and pericentral regions of the perfused rat liver by xylitol European Journal of Biochemistry. 137: 1-6. PMID 6606574 DOI: 10.1111/J.1432-1033.1983.Tb07787.X  0.354
1983 Thurman RG, Kauffman FC, JI S, Lemasters JJ, Conway JG, Belinsky SA, Kashiwagi T, Matsumura T. Metabolic heterogeneity in the perfused rat liver Pharmacology, Biochemistry and Behavior. 18: 415-419. PMID 6356163 DOI: 10.1016/0091-3057(83)90209-5  0.337
1982 Ji S, Lemasters JJ, Christenson V, Thurman RG. Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver: evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia. Proceedings of the National Academy of Sciences of the United States of America. 79: 5415-9. PMID 6957871 DOI: 10.1073/Pnas.79.17.5415  0.337
1981 Lemasters JJ, Ji S, Thurman RG. Centrilobular injury following hypoxia in isolated, perfused rat liver. Science (New York, N.Y.). 213: 661-3. PMID 7256265 DOI: 10.1126/Science.7256265  0.368
1981 Ji S, Lemasters JJ, Thurman RG. Ethanol-induced changes in the intralobular oxygen gradient of perfused rat liver. Pharmacology, Biochemistry, and Behavior. 41-5. PMID 7243833 DOI: 10.1016/S0091-3057(80)80007-4  0.361
1980 Hackenbrock CR, Schneider H, Lemasters JJ, Höchli M. Relationships between bilayer lipid, motional freedom of oxidoreductase components, and electron transfer in the mitochondrial inner membrane. Advances in Experimental Medicine and Biology. 132: 245-63. PMID 7424710 DOI: 10.1007/978-1-4757-1419-7_26  0.34
1980 Ji S, Lemasters JJ, Thurman RG. A non-invasive method to study metabolic events within sublobular regions of hemoglobin-free perfused liver. Febs Letters. 113: 37-42. PMID 7380004 DOI: 10.1016/0014-5793(80)80489-3  0.305
1980 Lemasters JJ. Near thermodynamic equilibrium of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria. Febs Letters. 110: 96-100. PMID 7353670 DOI: 10.1016/0014-5793(80)80032-9  0.382
1980 Schneider H, Lemasters JJ, Höchli M, Hackenbrock CR. Fusion of liposomes with mitochondrial inner membranes. Proceedings of the National Academy of Sciences of the United States of America. 77: 442-6. PMID 6928637 DOI: 10.1073/Pnas.77.1.442  0.311
1980 Ji S, Lemasters JJ, Thurman RG. Differential pyridine nucleotide reduction in periportal and pericentral regions of the liver lobule of the hemoglobin-free perfused liver from phenobarbital-treated rats following alcohol treatment Drug and Alcohol Dependence. 6: 7-8. DOI: 10.1016/0376-8716(80)90336-1  0.335
1979 Lemasters JJ, Hackenbrock CR. Continuous measurement of adenosine triphosphate with firefly luciferase luminescence. Methods in Enzymology. 56: 530-44. PMID 459883 DOI: 10.1016/0076-6879(79)56051-0  0.33
1978 Lemasters JJ. Possible role of the mitochondrial outer membrane as an oncotic regulator of mitochondrial volume. Febs Letters. 88: 10-4. PMID 639975 DOI: 10.1016/0014-5793(78)80595-X  0.433
1978 Lemasters JJ, Hackenbrock CR. [4] Firefly luciferase assay for ATP production by mitochondria Methods in Enzymology. 57: 36-50. DOI: 10.1016/0076-6879(78)57006-7  0.355
1974 Lemasters JJ, Hackenbrock CE. Adenosine triphosphate: continuous measurement in mitochondrial suspension by firefly luciferase luminescence. Biochemical and Biophysical Research Communications. 55: 1262-70. PMID 4771996 DOI: 10.1016/S0006-291X(73)80030-0  0.307
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