Joseph N. Blattman, Ph.D. - Publications

Affiliations: 
2001 Emory University, Atlanta, GA 
Area:
Immunology, Microbiology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 DiPalma MP, Blattman JN. The impact of microbiome dysbiosis on T cell function within the tumor microenvironment (TME). Frontiers in Cell and Developmental Biology. 11: 1141215. PMID 37009485 DOI: 10.3389/fcell.2023.1141215  0.429
2022 Manhas KR, Blattman JN. Flow Cytometry Analysis of Immune Cell Responses. Methods in Molecular Biology (Clifton, N.J.). 2597: 105-120. PMID 36374417 DOI: 10.1007/978-1-0716-2835-5_9  0.32
2022 Manhas KR, Marshall PA, Wagner CE, Jurutka PW, Mancenido MV, Debray HZ, Blattman JN. Rexinoids Modulate Effector T Cell Expression of Mucosal Homing Markers CCR9 and α4β7 Integrin and Direct Their Migration . Frontiers in Immunology. 13: 746484. PMID 35154092 DOI: 10.3389/fimmu.2022.746484  0.332
2021 Christie JD, Appel N, Canter H, Achi JG, Elliott NM, de Matos AL, Franco L, Kilbourne J, Lowe K, Rahman MM, Villa NY, Carmen J, Luna E, Blattman J, McFadden G. Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eliminates lung metastatic mouse osteosarcoma. Molecular Therapy Oncolytics. 22: 539-554. PMID 34553039 DOI: 10.1016/j.omto.2021.07.014  0.787
2018 Woolf EC, Manhas KR, Healey DR, Blattman JN, Scheck AC. Abstract 2739: The ketone body β-hydroxybutyrate alters expression of PD-L1 on malignant glioma cells but does not directly affect T cells in vitro Cancer Research. 78: 2739-2739. DOI: 10.1158/1538-7445.Am2018-2739  0.561
2017 Franco LS, Holechek SA, Caplan MR, Blattman JN. Sequence-specific detection of different strains of LCMV in a single sample using tentacle probes. Virology Journal. 14: 197. PMID 29029641 DOI: 10.1186/S12985-017-0863-9  0.745
2017 Brusch GA, Billy G, Blattman JN, DeNardo DF. Reproduction Alters Hydration State but Does Not Impact the Positive Effects of Dehydration on Innate Immune Function in Children's Pythons (Antaresia childreni). Physiological and Biochemical Zoology : Pbz. 90: 646-654. PMID 28991506 DOI: 10.1086/694834  0.32
2017 Meador LR, Kessans SA, Kilbourne J, Kibler KV, Pantaleo G, Roderiguez ME, Blattman JN, Jacobs BL, Mor TS. A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles. Virology. 507: 242-256. PMID 28458036 DOI: 10.1016/J.Virol.2017.04.008  0.417
2016 Holechek SA, McAfee MS, Nieves LM, Guzman VP, Manhas K, Fouts T, Bagley K, Blattman JN. Retinaldehyde dehydrogenase 2 as a molecular adjuvant for enhancement of mucosal immunity during DNA vaccination. Vaccine. PMID 27670072 DOI: 10.1016/J.Vaccine.2016.09.013  0.787
2016 Lettieri CK, Appel N, Labban N, Lussier DM, Blattman JN, Hingorani P. Progress and opportunities for immune therapeutics in osteosarcoma. Immunotherapy. 8: 1233-44. PMID 27605071 DOI: 10.2217/Imt-2016-0048  0.788
2016 Lussier DM, Woolf EC, Johnson JL, Brooks KS, Blattman JN, Scheck AC. Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet. Bmc Cancer. 16: 310. PMID 27178315 DOI: 10.1186/S12885-016-2337-7  0.783
2016 Cook R, Meador L, Ausvasomrit A, Boonsompong T, Schaefer B, Mor T, Blattman J, Sirianni R. IMST-50. DEVELOPMENT AND EXPRESSION OF A T CELL ENGAGER TARGETED TO GLIOBLASTOMA BY CHLOROTOXIN Neuro-Oncology. 18: vi97-vi98. DOI: 10.1093/Neuonc/Now212.406  0.44
2015 McAfee MS, Huynh TP, Johnson JL, Jacobs BL, Blattman JN. Interaction between unrelated viruses during in vivo co-infection to limit pathology and immunity. Virology. 484: 153-162. PMID 26099694 DOI: 10.1016/J.Virol.2015.05.021  0.771
2015 Lussier DM, Johnson JL, Hingorani P, Blattman JN. Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcoma. Journal For Immunotherapy of Cancer. 3: 21. PMID 25992292 DOI: 10.1186/S40425-015-0067-Z  0.786
2015 Chowell D, Krishna S, Becker PD, Cocita C, Shu J, Tan X, Greenberg PD, Klavinskis LS, Blattman JN, Anderson KS. TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes. Proceedings of the National Academy of Sciences of the United States of America. 112: E1754-62. PMID 25831525 DOI: 10.1073/Pnas.1500973112  0.607
2015 Lussier DM, O'Neill L, Nieves LM, McAfee MS, Holechek SA, Collins AW, Dickman P, Jacobsen J, Hingorani P, Blattman JN. Enhanced T-cell immunity to osteosarcoma through antibody blockade of PD-1/PD-L1 interactions. Journal of Immunotherapy (Hagerstown, Md. : 1997). 38: 96-106. PMID 25751499 DOI: 10.1097/Cji.0000000000000065  0.768
2015 Johnson JL, Woolf E, Lussier DM, Brooks KS, Blattman JN, Scheck AC. Abstract B73: Ketogenic diet enhances immunity to glioblastoma Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-B73  0.826
2015 Woolf EC, Johnson JL, Lussier DM, Brooks KS, Blattman JN, Scheck AC. Abstract 1344: The ketogenic diet enhances immunity in a mouse model of malignant glioma Cancer Research. 75: 1344-1344. DOI: 10.1158/1538-7445.Am2015-1344  0.83
2014 Blattman NN, Lagunoff M, Blattman JN, Corey L. Nuclear factor kappa B is required for the production of infectious human herpesvirus 8 virions. Frontiers in Microbiology. 5: 129. PMID 24795700 DOI: 10.3389/Fmicb.2014.00129  0.386
2013 Zarnitsyna VI, Evavold BD, Schoettle LN, Blattman JN, Antia R. Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire. Frontiers in Immunology. 4: 485. PMID 24421780 DOI: 10.3389/Fimmu.2013.00485  0.491
2013 Demidenko AA, Blattman JN, Blattman NN, Greenberg PD, Nibert ML. Engineering recombinant reoviruses with tandem repeats and a tetravirus 2A-like element for exogenous polypeptide expression. Proceedings of the National Academy of Sciences of the United States of America. 110: E1867-76. PMID 23630248 DOI: 10.1073/Pnas.1220107110  0.528
2013 Lussier DM, Nieves LM, McAfee MS, Hyunh TP, Holechek SA, Hingorani P, Blattman JN. Enhancement of T cell immunity to osteosarcoma through modulation of PD-1/PD-L1 interactions Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P162  0.773
2012 Wegmann F, Gartlan KH, Harandi AM, Brinckmann SA, Coccia M, Hillson WR, Kok WL, Cole S, Ho LP, Lambe T, Puthia M, Svanborg C, Scherer EM, Krashias G, Williams A, ... Blattman JN, et al. Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens. Nature Biotechnology. 30: 883-8. PMID 22922673 DOI: 10.1038/Nbt.2344  0.605
2012 Stromnes IM, Fowler C, Casamina CC, Georgopolos CM, McAfee MS, Schmitt TM, Tan X, Kim TD, Choi I, Blattman JN, Greenberg PD. Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 189: 1812-25. PMID 22798667 DOI: 10.4049/Jimmunol.1200552  0.8
2012 McAfee MS, Blattman JN. Combating chronic T-cell exhaustion. Immunotherapy. 4: 557-60. PMID 22788120 DOI: 10.2217/Imt.12.46  0.832
2012 Schietinger A, Delrow JJ, Basom RS, Blattman JN, Greenberg PD. Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state. Science (New York, N.Y.). 335: 723-7. PMID 22267581 DOI: 10.1126/Science.1214277  0.662
2011 Tan X, Sande JL, Pufnock JS, Blattman JN, Greenberg PD. Retinoic acid as a vaccine adjuvant enhances CD8+ T cell response and mucosal protection from viral challenge. Journal of Virology. 85: 8316-27. PMID 21653670 DOI: 10.1128/Jvi.00781-11  0.69
2011 Johnson PL, Kochin BF, McAfee MS, Stromnes IM, Regoes RR, Ahmed R, Blattman JN, Antia R. Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections. Journal of Virology. 85: 5565-70. PMID 21411537 DOI: 10.1128/Jvi.00166-11  0.81
2011 Rhee EG, Blattman JN, Kasturi SP, Kelley RP, Kaufman DR, Lynch DM, La Porte A, Simmons NL, Clark SL, Pulendran B, Greenberg PD, Barouch DH. Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors. Journal of Virology. 85: 315-23. PMID 20962088 DOI: 10.1128/Jvi.01597-10  0.601
2010 Stromnes IM, Blattman JN, Tan X, Jeevanjee S, Gu H, Greenberg PD. Abrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice. The Journal of Clinical Investigation. 120: 3722-34. PMID 20890046 DOI: 10.1172/Jci41991  0.793
2010 Fowler CC, Pao LI, Blattman JN, Greenberg PD. SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 3256-67. PMID 20696858 DOI: 10.4049/Jimmunol.1001362  0.825
2009 Blattman JN, Wherry EJ, Ha SJ, van der Most RG, Ahmed R. Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. Journal of Virology. 83: 4386-94. PMID 19211743 DOI: 10.1128/Jvi.02524-08  0.751
2009 Blattman J, Tan X, Sande J, Pufnock J, Greenberg P. P02-05. All-trans retinoic acid during vaccination increases Ag-specific CD8 T cell homing to mucosal sites and improves recall responses to vaginal challenge Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P10  0.625
2007 Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity. 27: 670-84. PMID 17950003 DOI: 10.1016/J.Immuni.2007.09.006  0.787
2007 Shin H, Blackburn SD, Blattman JN, Wherry EJ. Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection. The Journal of Experimental Medicine. 204: 941-9. PMID 17420267 DOI: 10.1084/Jem.20061937  0.674
2007 Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006) Immunity. 27: 824. DOI: 10.1016/J.Immuni.2007.11.006  0.763
2006 Blattman JN, Greenberg PD. PD-1 blockade: rescue from a near-death experience. Nature Immunology. 7: 227-8. PMID 16482167 DOI: 10.1038/Ni0306-227  0.665
2005 Wherry EJ, Blattman JN, Ahmed R. Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. Journal of Virology. 79: 8960-8. PMID 15994790 DOI: 10.1128/Jvi.79.14.8960-8968.2005  0.704
2004 Wherry EJ, Barber DL, Kaech SM, Blattman JN, Ahmed R. Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 16004-9. PMID 15505208 DOI: 10.1073/Pnas.0407192101  0.782
2004 Zhang Y, Blattman JN, Kennedy NJ, Duong J, Nguyen T, Wang Y, Davis RJ, Greenberg PD, Flavell RA, Dong C. Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Nature. 430: 793-7. PMID 15306813 DOI: 10.1038/Nature02764  0.637
2004 Blattman JN, Greenberg PD. Cancer immunotherapy: a treatment for the masses. Science (New York, N.Y.). 305: 200-5. PMID 15247469 DOI: 10.1126/Science.1100369  0.611
2003 van der Most RG, Murali-Krishna K, Lanier JG, Wherry EJ, Puglielli MT, Blattman JN, Sette A, Ahmed R. Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation. Virology. 315: 93-102. PMID 14592762 DOI: 10.1016/J.Virol.2003.07.001  0.803
2003 Topp MS, Riddell SR, Akatsuka Y, Jensen MC, Blattman JN, Greenberg PD. Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production. The Journal of Experimental Medicine. 198: 947-55. PMID 12963692 DOI: 10.1084/Jem.20021288  0.637
2003 Ho WY, Blattman JN, Dossett ML, Yee C, Greenberg PD. Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction. Cancer Cell. 3: 431-7. PMID 12781360 DOI: 10.1016/S1535-6108(03)00113-2  0.793
2003 Blattman JN, Grayson JM, Wherry EJ, Kaech SM, Smith KA, Ahmed R. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nature Medicine. 9: 540-7. PMID 12692546 DOI: 10.1038/Nm866  0.749
2003 Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. Journal of Virology. 77: 4911-27. PMID 12663797 DOI: 10.1128/Jvi.77.8.4911-4927.2003  0.73
2003 Seiffert M, Custodio JM, Wolf I, Harkey M, Liu Y, Blattman JN, Greenberg PD, Rohrschneider LR. Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent. Molecular and Cellular Biology. 23: 2415-24. PMID 12640125 DOI: 10.1128/Mcb.23.7.2415-2424.2003  0.569
2003 Slifka MK, Blattman JN, Sourdive DJ, Liu F, Huffman DL, Wolfe T, Hughes A, Oldstone MB, Ahmed R, Von Herrath MG. Preferential escape of subdominant CD8+ T cells during negative selection results in an altered antiviral T cell hierarchy. Journal of Immunology (Baltimore, Md. : 1950). 170: 1231-9. PMID 12538681 DOI: 10.4049/Jimmunol.170.3.1231  0.721
2002 Blattman JN, Cheng LE, Greenberg PD. CD8(+) T cell responses: it's all downhill after their prime. Nature Immunology. 3: 601-2. PMID 12087413 DOI: 10.1038/Ni0702-601  0.812
2002 Blattman JN, Antia R, Sourdive DJ, Wang X, Kaech SM, Murali-Krishna K, Altman JD, Ahmed R. Estimating the precursor frequency of naive antigen-specific CD8 T cells. The Journal of Experimental Medicine. 195: 657-64. PMID 11877489 DOI: 10.1084/Jem.20001021  0.728
2000 Blattman JN, Sourdive DJ, Murali-Krishna K, Ahmed R, Altman JD. Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 6081-90. PMID 11086040 DOI: 10.4049/Jimmunol.165.11.6081  0.64
1998 Zajac AJ, Blattman JN, Murali-Krishna K, Sourdive DJ, Suresh M, Altman JD, Ahmed R. Viral immune evasion due to persistence of activated T cells without effector function. The Journal of Experimental Medicine. 188: 2205-13. PMID 9858507 DOI: 10.1084/Jem.188.12.2205  0.646
1998 Zajac AJ, Murali-Krishna K, Blattman JN, Ahmed R. Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells. Current Opinion in Immunology. 10: 444-9. PMID 9722921 DOI: 10.1016/S0952-7915(98)80119-2  0.638
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