Michael H. Overholtzer, Ph.D. - Publications

Affiliations: 
Sloan Kettering Institute, New York, NY, United States 
Area:
Molecular Biology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kim S, Lee D, Kim SE, Overholtzer M. Entosis: the core mechanism and crosstalk with other cell death programs. Experimental & Molecular Medicine. PMID 38565900 DOI: 10.1038/s12276-024-01227-w  0.385
2021 Overholtzer M. Cell death leaves a new TRAIL. The Journal of Cell Biology. 220. PMID 34643655 DOI: 10.1083/jcb.202109018  0.336
2021 Kim SE, Zhang J, Jiang E, Overholtzer M. Amino acids and mechanistic target of rapamycin regulate the fate of live engulfed cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21909. PMID 34547144 DOI: 10.1096/fj.202100870R  0.395
2021 Chen R, Ram A, Albeck JG, Overholtzer M. Entosis is induced by ultraviolet radiation. Iscience. 24: 102902. PMID 34401679 DOI: 10.1016/j.isci.2021.102902  0.356
2020 Lee C, Lamech L, Johns E, Overholtzer M. Selective Lysosome Membrane Turnover Is Induced by Nutrient Starvation. Developmental Cell. PMID 32916093 DOI: 10.1016/J.Devcel.2020.08.008  0.342
2020 Riegman M, Sagie L, Galed C, Levin T, Steinberg N, Dixon SJ, Wiesner U, Bradbury MS, Niethammer P, Zaritsky A, Overholtzer M. Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture. Nature Cell Biology. 22: 1042-1048. PMID 32868903 DOI: 10.1038/S41556-020-0565-1  0.487
2020 Hayashi A, Yavas A, McIntyre CA, Ho YJ, Erakky A, Wong W, Varghese AM, Melchor JP, Overholtzer M, O'Reilly EM, Klimstra DS, Basturk O, Iacobuzio-Donahue CA. Genetic and clinical correlates of entosis in pancreatic ductal adenocarcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32350415 DOI: 10.1038/S41379-020-0549-5  0.355
2019 Overholtzer M. Senescent cells feed on their neighbours Nature. 574: 635-636. PMID 31659315 DOI: 10.1038/D41586-019-03271-3  0.446
2019 Riegman M, Bradbury MS, Overholtzer M. Population Dynamics in Cell Death: Mechanisms of Propagation Trends in Cancer. 5: 558-568. PMID 31474361 DOI: 10.1016/J.Trecan.2019.07.008  0.467
2019 Florey O, Overholtzer M. Macropinocytosis and autophagy crosstalk in nutrient scavenging. Philosophical Transactions of the Royal Society B. 374: 20180154. PMID 30967004 DOI: 10.1098/Rstb.2018.0154  0.374
2019 Lee Y, Hamann JC, Pellegrino M, Durgan J, Domart MC, Collinson LM, Haynes CM, Florey O, Overholtzer M. Entosis Controls a Developmental Cell Clearance in C. elegans. Cell Reports. 26: 3212-3220.e4. PMID 30893595 DOI: 10.1016/J.Celrep.2019.02.073  0.48
2019 Hamann JC, Kim SE, Overholtzer M. Methods for the Study of Entotic Cell Death. Methods in Molecular Biology (Clifton, N.J.). 1880: 447-454. PMID 30610714 DOI: 10.1007/978-1-4939-8873-0_28  0.47
2018 Fais S, Overholtzer M. Cell-in-cell phenomena in cancer. Nature Reviews Cancer. 18: 758-766. PMID 30420767 DOI: 10.1038/S41568-018-0073-9  0.447
2018 Hawk MA, Gorsuch CL, Fagan P, Lee C, Kim SE, Hamann JC, Mason JA, Weigel KJ, Tsegaye MA, Shen L, Shuff S, Zuo J, Hu S, Jiang L, Chapman S, ... ... Overholtzer M, et al. RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells. Nature Cell Biology. PMID 29459781 DOI: 10.1038/S41556-018-0034-2  0.487
2018 Fais S, Overholtzer M. Cell-in-cell phenomena, cannibalism, and autophagy: is there a relationship? Cell Death and Disease. 9: 95-95. PMID 29367622 DOI: 10.1038/S41419-017-0111-7  0.456
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Overholtzer M, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.459
2017 Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021  0.388
2017 Durgan J, Tseng YY, Hamann JC, Domart MC, Collinson L, Hall A, Overholtzer M, Florey O. Mitosis can drive cell cannibalism through entosis. Elife. 6. PMID 28693721 DOI: 10.7554/Elife.27134  0.461
2017 Hamann JC, Surcel A, Chen R, Teragawa C, Albeck JG, Robinson DN, Overholtzer M. Entosis Is Induced by Glucose Starvation. Cell Reports. 20: 201-210. PMID 28683313 DOI: 10.1016/J.Celrep.2017.06.037  0.478
2017 Zaritsky A, Tseng YY, Rabadán MA, Krishna S, Overholtzer M, Danuser G, Hall A. Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration. The Journal of Cell Biology. PMID 28512143 DOI: 10.1083/Jcb.201609095  0.365
2017 Durgan J, Tseng Y, Hamann JC, Domart M, Collinson L, Hall A, Overholtzer M, Florey O. Author response: Mitosis can drive cell cannibalism through entosis Elife. DOI: 10.7554/Elife.27134.031  0.358
2016 Krishna S, Overholtzer M. Germ Cells Get by with a Little Cannibalistic Help from Their Friends. Developmental Cell. 39: 631-633. PMID 27997820 DOI: 10.1016/J.Devcel.2016.12.003  0.412
2016 Kim SE, Zhang L, Ma K, Riegman M, Chen F, Ingold I, Conrad M, Turker MZ, Gao M, Jiang X, Monette S, Pauliah M, Gonen M, Zanzonico P, Quinn T, ... ... Overholtzer M, et al. Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth. Nature Nanotechnology. PMID 27668796 DOI: 10.1038/Nnano.2016.164  0.343
2016 Krishna S, Palm W, Lee Y, Yang W, Bandyopadhyay U, Xu H, Florey O, Thompson CB, Overholtzer M. PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment. Developmental Cell. 38: 536-547. PMID 27623384 DOI: 10.1016/J.Devcel.2016.08.001  0.43
2016 Bandyopadhyay U, Overholtzer M. LAP: the protector against autoimmunity. Cell Research. PMID 27297234 DOI: 10.1038/Cr.2016.70  0.351
2016 O'Sullivan TE, Geary CD, Weizman OE, Geiger TL, Rapp M, Dorn GW, Overholtzer M, Sun JC. Atg5 Is Essential for the Development and Survival of Innate Lymphocytes. Cell Reports. PMID 27210760 DOI: 10.1016/J.Celrep.2016.04.082  0.407
2016 Hamann J, Overholtzer M. Killing me softly: microparticles target deformable cells. Cell Research. 26: 637-638. PMID 27167570 DOI: 10.1038/Cr.2016.54  0.341
2016 Krishna S, Overholtzer M. Mechanisms and consequences of entosis. Cellular and Molecular Life Sciences : Cmls. 73: 2379-86. PMID 27048820 DOI: 10.1007/S00018-016-2207-0  0.488
2016 Bui DA, Lee W, White AE, Harper JW, Schackmann RC, Overholtzer M, Selfors LM, Brugge JS. Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP. Science Signaling. 9: ra23. PMID 26933062 DOI: 10.1126/Scisignal.Aaa9227  0.399
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Overholtzer M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.337
2015 Sun Q, Huang H, Overholtzer M. Cell-in-cell structures are involved in the competition between cells in human tumors. Molecular & Cellular Oncology. 2: e1002707. PMID 27308493 DOI: 10.1080/23723556.2014.1002707  0.491
2015 Overholtzer M, Wang X. Editorial: Cell-in-Cell: A Century-Old Mystery Comes to the Table. Current Molecular Medicine. PMID 26511702  0.325
2015 Lee Y, Overholtzer M. In-cell infection: bringing uninvited guests. Cell Research. 25: 647-648. PMID 25952669 DOI: 10.1038/Cr.2015.57  0.442
2015 Jiang X, Overholtzer M, Thompson CB. Autophagy in cellular metabolism and cancer. The Journal of Clinical Investigation. 125: 47-54. PMID 25654550 DOI: 10.1172/Jci73942  0.399
2015 Florey O, Gammoh N, Kim SE, Jiang X, Overholtzer M. V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation. Autophagy. 11: 88-99. PMID 25484071 DOI: 10.4161/15548627.2014.984277  0.347
2015 Benezra M, Phillips E, Overholtzer M, Zanzonico PB, Tuominen E, Wiesner U, Bradbury MS. Ultrasmall integrin-targeted silica nanoparticles modulate signaling events and cellular processes in a concentration-dependent manner. Small (Weinheim An Der Bergstrasse, Germany). 11: 1721-32. PMID 25471698 DOI: 10.1002/Smll.201402331  0.365
2014 Krishna S, Overholtzer M. Milk makes lysosomes lethal. Nature Cell Biology. 16: 1029-31. PMID 25358350 DOI: 10.1038/Ncb3059  0.334
2014 Sun Q, Luo T, Ren Y, Florey O, Shirasawa S, Sasazuki T, Robinson DN, Overholtzer M. Competition between human cells by entosis. Cell Research. 24: 1299-310. PMID 25342560 DOI: 10.1038/Cr.2014.138  0.484
2014 Sun Q, Cibas ES, Huang H, Hodgson L, Overholtzer M. Induction of entosis by epithelial cadherin expression. Cell Research. 24: 1288-98. PMID 25342558 DOI: 10.1038/Cr.2014.137  0.465
2014 Nair-Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y, Banerjee M, Overholtzer M, Roche PA, Tampé R, Brown BD, Amsen D, Whiteheart SW, Blander JM. TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation. Cell. 158: 506-21. PMID 25083866 DOI: 10.1016/J.Cell.2014.04.054  0.32
2014 Sun Q, Luo T, Ren Y, Florey O, Cibas ES, Hodgson L, Robinson DN, Overholtzer M. Abstract SY29-03: Competition between tumor cells by entosis Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy29-03  0.505
2013 Krajcovic M, Krishna S, Akkari L, Joyce JA, Overholtzer M. mTOR regulates phagosome and entotic vacuole fission. Molecular Biology of the Cell. 24: 3736-45. PMID 24088573 DOI: 10.1091/Mbc.E13-07-0408  0.456
2013 Sun Q, Overholtzer M. Methods for the study of entosis. Methods of Molecular Biology. 1004: 59-66. PMID 23733569 DOI: 10.1007/978-1-62703-383-1_5  0.46
2013 Kim SE, Overholtzer M. Autophagy proteins regulate cell engulfment mechanisms that participate in cancer. Seminars in Cancer Biology. 23: 329-36. PMID 23726896 DOI: 10.1016/J.Semcancer.2013.05.004  0.433
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Overholtzer M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.305
2012 Florey O, Overholtzer M. Autophagy proteins in macroendocytic engulfment. Trends in Cell Biology. 22: 374-380. PMID 22608991 DOI: 10.1016/J.Tcb.2012.04.005  0.372
2012 Krajcovic M, Overholtzer M. Mechanisms of Ploidy Increase in Human Cancers: A New Role for Cell Cannibalism Cancer Research. 72: 1596-1601. PMID 22447569 DOI: 10.1158/0008-5472.Can-11-3127  0.468
2011 Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nature Cell Biology. 13: 1335-43. PMID 22002674 DOI: 10.1038/Ncb2363  0.43
2011 Krajcovic M, Johnson NB, Sun Q, Normand G, Hoover N, Yao E, Richardson AL, King RW, Cibas ES, Schnitt SJ, Brugge JS, Overholtzer M. A non-genetic route to aneuploidy in human cancers. Nature Cell Biology. 13: 324-30. PMID 21336303 DOI: 10.1038/Ncb2174  0.46
2011 Overholtzer M. Abstract SY09-03: Entosis: Adhesion, autophagy, and murder Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy09-03  0.524
2010 Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 5012-7. PMID 20194747 DOI: 10.1073/Pnas.1000896107  0.401
2009 Zhang J, Ji JY, Yu M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nature Cell Biology. 11: 1444-50. PMID 19935651 DOI: 10.1038/Ncb1993  0.47
2009 Zhang J, Ji J, Yi M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA. Abstract LB-228: YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-228  0.46
2009 Schafer Z, Grassian A, Song L, Mailleux A, Schmelzle T, Irie Y, Gao G, Overholtzer M, Jiang Z, Gerhart‐Hines Z, Puigsever P, Brugge JS. Abstract IA-13: Mechanisms regulating anchorage independent survival Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-Ia-13  0.448
2008 Overholtzer M, Brugge JS. The cell biology of cell-in-cell structures. Nature Reviews. Molecular Cell Biology. 9: 796-809. PMID 18784728 DOI: 10.1038/Nrm2504  0.452
2008 Mailleux AA, Overholtzer M, Brugge JS. Lumen formation during mammary epithelial morphogenesis: insights from in vitro and in vivo models. Cell Cycle (Georgetown, Tex.). 7: 57-62. PMID 18196964 DOI: 10.4161/Cc.7.1.5150  0.414
2007 Overholtzer M, Mailleux AA, Mouneimne G, Normand G, Schnitt SJ, King RW, Cibas ES, Brugge JS. A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion. Cell. 131: 966-79. PMID 18045538 DOI: 10.1016/J.Cell.2007.10.040  0.489
2007 Schmelzle T, Mailleux AA, Overholtzer M, Carroll JS, Solimini NL, Lightcap ES, Veiby OP, Brugge JS. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 3787-92. PMID 17360431 DOI: 10.1073/Pnas.0700115104  0.456
2007 Mailleux AA, Overholtzer M, Schmelzle T, Bouillet P, Strasser A, Brugge JS. BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Developmental Cell. 12: 221-34. PMID 17276340 DOI: 10.1016/J.Devcel.2006.12.003  0.457
2006 Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proceedings of the National Academy of Sciences of the United States of America. 103: 12405-10. PMID 16894141 DOI: 10.1073/Pnas.0605579103  0.4
2004 Chen W, Cooper TK, Zahnow CA, Overholtzer M, Zhao Z, Ladanyi M, Karp JE, Gokgoz N, Wunder JS, Andrulis IL, Levine AJ, Mankowski JL, Baylin SB. Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis. Cancer Cell. 6: 387-98. PMID 15488761 DOI: 10.1016/J.Ccr.2004.08.030  0.428
2003 Overholtzer M, Rao PH, Favis R, Lu XY, Elowitz MB, Barany F, Ladanyi M, Gorlick R, Levine AJ. The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 100: 11547-52. PMID 12972634 DOI: 10.1073/Pnas.1934852100  0.447
2003 Jin S, Kalkum M, Overholtzer M, Stoffel A, Chait BT, Levine AJ. CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. Genes & Development. 17: 359-67. PMID 12569127 DOI: 10.1101/Gad.1047003  0.487
2002 Su F, Overholtzer M, Besser D, Levine AJ. WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. Genes & Development. 16: 46-57. PMID 11782444 DOI: 10.1101/Gad.942902  0.639
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