Year |
Citation |
Score |
2023 |
Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, et al. A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. Nature Cell Biology. PMID 37857833 DOI: 10.1038/s41556-023-01248-z |
0.337 |
|
2022 |
Cohen A, Jeng EE, Voorhies M, Symington J, Ali N, Rodriguez RA, Bassik MC, Sil A. Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages. Plos Pathogens. 18: e1010237. PMID 36174103 DOI: 10.1371/journal.ppat.1010237 |
0.348 |
|
2022 |
Azimova D, Herrera N, Duvenage L, Voorhies M, Rodriguez RA, English BC, Hoving JC, Rosenberg O, Sil A. Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. Plos Pathogens. 18: e1010417. PMID 35731824 DOI: 10.1371/journal.ppat.1010417 |
0.431 |
|
2022 |
Mandel MA, Beyhan S, Voorhies M, Shubitz LF, Galgiani JN, Orbach MJ, Sil A. The WOPR family protein Ryp1 is a key regulator of gene expression, development, and virulence in the thermally dimorphic fungal pathogen Coccidioides posadasii. Plos Pathogens. 18: e1009832. PMID 35385558 DOI: 10.1371/journal.ppat.1009832 |
0.372 |
|
2020 |
Mead ME, Borowsky AT, Joehnk B, Steenwyk JL, Shen XX, Sil A, Rokas A. Recurrent loss of abaA, a master regulator of asexual development in filamentous fungi, correlates with changes in genomic and morphological traits. Genome Biology and Evolution. PMID 32442273 DOI: 10.1093/Gbe/Evaa107 |
0.384 |
|
2019 |
Sil A. Molecular regulation of Histoplasma dimorphism. Current Opinion in Microbiology. 52: 151-157. PMID 31739263 DOI: 10.1016/J.Mib.2019.10.011 |
0.365 |
|
2019 |
Rodriguez L, Voorhies M, Gilmore S, Beyhan S, Myint A, Sil A. Opposing signaling pathways regulate morphology in response to temperature in the fungal pathogen Histoplasma capsulatum. Plos Biology. 17: e3000168. PMID 31568523 DOI: 10.1371/Journal.Pbio.3000168 |
0.487 |
|
2019 |
Beyhan S, Sil A. Sensing the heat and the host: Virulence determinants of . Virulence. 10: 793-800. PMID 31560240 DOI: 10.1080/21505594.2019.1663596 |
0.444 |
|
2017 |
English BC, Van Prooyen N, Örd T, Örd T, Sil A. The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum. Plos Pathogens. 13: e1006589. PMID 28953979 DOI: 10.1371/Journal.Ppat.1006589 |
0.519 |
|
2016 |
Van Prooyen N, Henderson CA, Hocking Murray D, Sil A. CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans. Plos Pathogens. 12: e1005749. PMID 27459510 DOI: 10.1371/Journal.Ppat.1005749 |
0.455 |
|
2015 |
Isaac DT, Berkes CA, English BC, Hocking Murray D, Lee YN, Coady A, Sil A. Macrophage cell death and transcriptional response are actively triggered by the fungal virulence factor Cbp1 during H. capsulatum infection. Molecular Microbiology. 98: 910-29. PMID 26288377 DOI: 10.1111/Mmi.13168 |
0.726 |
|
2015 |
Gilmore SA, Voorhies M, Gebhart D, Sil A. Genome-Wide Reprogramming of Transcript Architecture by Temperature Specifies the Developmental States of the Human Pathogen Histoplasma. Plos Genetics. 11: e1005395. PMID 26177267 DOI: 10.1371/Journal.Pgen.1005395 |
0.452 |
|
2015 |
Coady A, Sil A. MyD88-dependent signaling drives host survival and early cytokine production during Histoplasma capsulatum infection. Infection and Immunity. 83: 1265-75. PMID 25583527 DOI: 10.1128/Iai.02619-14 |
0.72 |
|
2015 |
Sil A, Andrianopoulos A. Thermally Dimorphic Human Fungal Pathogens--Polyphyletic Pathogens with a Convergent Pathogenicity Trait. Cold Spring Harbor Perspectives in Medicine. 5: a019794. PMID 25384771 DOI: 10.1101/Cshperspect.A019794 |
0.392 |
|
2013 |
Gilmore SA, Naseem S, Konopka JB, Sil A. N-acetylglucosamine (GlcNAc) triggers a rapid, temperature-responsive morphogenetic program in thermally dimorphic fungi. Plos Genetics. 9: e1003799. PMID 24068964 DOI: 10.1371/Journal.Pgen.1003799 |
0.482 |
|
2013 |
Beyhan S, Gutierrez M, Voorhies M, Sil A. A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Plos Biology. 11: e1001614. PMID 23935449 DOI: 10.1371/Journal.Pbio.1001614 |
0.486 |
|
2013 |
Inglis DO, Voorhies M, Hocking Murray DR, Sil A. Comparative transcriptomics of infectious spores from the fungal pathogen Histoplasma capsulatum reveals a core set of transcripts that specify infectious and pathogenic states. Eukaryotic Cell. 12: 828-52. PMID 23563482 DOI: 10.1128/Ec.00069-13 |
0.536 |
|
2013 |
Isaac DT, Coady A, Van Prooyen N, Sil A. The 3-hydroxy-methylglutaryl coenzyme A lyase HCL1 is required for macrophage colonization by human fungal pathogen Histoplasma capsulatum. Infection and Immunity. 81: 411-20. PMID 23184522 DOI: 10.1128/Iai.00833-12 |
0.72 |
|
2012 |
Muhammed M, Feldmesser M, Shubitz LF, Lionakis MS, Sil A, Wang Y, Glavis-Bloom J, Lewis RE, Galgiani JN, Casadevall A, Kontoyiannis DP, Mylonakis E. Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus. Virulence. 3: 329-38. PMID 22546902 DOI: 10.4161/Viru.20142 |
0.309 |
|
2012 |
Hwang LH, Seth E, Gilmore SA, Sil A. SRE1 regulates iron-dependent and -independent pathways in the fungal pathogen Histoplasma capsulatum. Eukaryotic Cell. 11: 16-25. PMID 22117028 DOI: 10.1128/Ec.05274-11 |
0.348 |
|
2012 |
Cain CW, Lohse MB, Homann OR, Sil A, Johnson AD. A conserved transcriptional regulator governs fungal morphology in widely diverged species. Genetics. 190: 511-21. PMID 22095082 DOI: 10.1534/Genetics.111.134080 |
0.586 |
|
2011 |
Voorhies M, Foo CK, Sil A. Experimental annotation of the human pathogen Histoplasma capsulatum transcribed regions using high-resolution tiling arrays. Bmc Microbiology. 11: 216. PMID 21958208 DOI: 10.1186/1471-2180-11-216 |
0.368 |
|
2010 |
Inglis DO, Berkes CA, Hocking Murray DR, Sil A. Conidia but not yeast cells of the fungal pathogen Histoplasma capsulatum trigger a type I interferon innate immune response in murine macrophages. Infection and Immunity. 78: 3871-82. PMID 20605974 DOI: 10.1128/Iai.00204-10 |
0.527 |
|
2008 |
Webster RH, Sil A. Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum. Proceedings of the National Academy of Sciences of the United States of America. 105: 14573-8. PMID 18791067 DOI: 10.1073/Pnas.0806221105 |
0.764 |
|
2008 |
Hwang LH, Mayfield JA, Rine J, Sil A. Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization. Plos Pathogens. 4: e1000044. PMID 18404210 DOI: 10.1371/Journal.Ppat.1000044 |
0.66 |
|
2008 |
Nguyen VQ, Sil A. Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator. Proceedings of the National Academy of Sciences of the United States of America. 105: 4880-5. PMID 18339808 DOI: 10.1073/Pnas.0710448105 |
0.527 |
|
2007 |
Fraser JA, Stajich JE, Tarcha EJ, Cole GT, Inglis DO, Sil A, Heitman J. Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii. Eukaryotic Cell. 6: 622-9. PMID 17337636 DOI: 10.1128/Ec.00018-07 |
0.385 |
|
2006 |
Gebhart D, Bahrami AK, Sil A. Identification of a copper-inducible promoter for use in ectopic expression in the fungal pathogen Histoplasma capsulatum. Eukaryotic Cell. 5: 935-44. PMID 16757741 DOI: 10.1128/Ec.00028-06 |
0.428 |
|
2005 |
Nittler MP, Hocking-Murray D, Foo CK, Sil A. Identification of Histoplasma capsulatum transcripts induced in response to reactive nitrogen species. Molecular Biology of the Cell. 16: 4792-813. PMID 16030248 DOI: 10.1091/Mbc.E05-05-0434 |
0.731 |
|
2003 |
Hwang L, Hocking-Murray D, Bahrami AK, Andersson M, Rine J, Sil A. Identifying phase-specific genes in the fungal pathogen Histoplasma capsulatum using a genomic shotgun microarray. Molecular Biology of the Cell. 14: 2314-26. PMID 12808032 DOI: 10.1091/Mbc.E03-01-0027 |
0.624 |
|
2001 |
McBride HJ, Sil A, Measday V, Yu Y, Moffat J, Maxon ME, Herskowitz I, Andrews B, Stillman DJ. The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae. Molecular Microbiology. 42: 345-53. PMID 11703659 DOI: 10.1046/J.1365-2958.2001.02601.X |
0.681 |
|
2000 |
Sil AK, Xin P, Hopper JE. Vectors allowing amplified expression of the Saccharomyces cerevisiae Gal3p-Gal80p-Gal4p transcription switch: Applications to galactose-regulated high-level production of proteins Protein Expression and Purification. 18: 202-212. PMID 10686151 DOI: 10.1006/Prep.1999.1177 |
0.306 |
|
1997 |
Takizawa PA, Sil A, Swedlow JR, Herskowitz I, Vale RD. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature. 389: 90-3. PMID 9288973 DOI: 10.1038/38015 |
0.554 |
|
1996 |
Sil A, Herskowitz I. Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene. Cell. 84: 711-22. PMID 8625409 DOI: 10.1016/S0092-8674(00)81049-1 |
0.62 |
|
1995 |
Kruger W, Peterson CL, Sil A, Coburn C, Arents G, Moudrianakis EN, Herskowitz I. Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription. Genes & Development. 9: 2770-9. PMID 7590252 DOI: 10.1101/Gad.9.22.2770 |
0.729 |
|
1992 |
Herskowitz I, Andrews B, Kruger W, Ogas J, Sil A, Coburn C, Peterson C. 36 Integration of Multiple Regulatory Inputs in the Control of HO Expression in Yeast Cold Spring Harbor Monograph Archive. 949-974. DOI: 10.1101/087969425.22B.949 |
0.768 |
|
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