Ronald Swanstrom - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Microbiology Biology

222 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Burdorf R, Zhou S, Amon C, Long N, Hill CS, Adams L, Tegha G, Chagomerana MB, Jumbe A, Maliwichi M, Wallie S, Li Y, Swanstrom R, Hosseinipour MC. Impact Of Low-Frequency HIV-1 Drug Resistance Mutations On Antiretroviral Therapy Outcomes. The Journal of Infectious Diseases. PMID 38462671 DOI: 10.1093/infdis/jiae131  0.311
2024 Bonner X, Sondgeroth A, McCue A, Nicely N, Tripathy A, Spielvogel E, Moeser M, Ke R, Leiderman K, Joseph SB, Swanstrom R. Stoichiometry for entry and binding properties of the Env protein of R5 T cell-tropic HIV-1 and its evolutionary variant of macrophage-tropic HIV-1. Mbio. e0032124. PMID 38426750 DOI: 10.1128/mbio.00321-24  0.317
2024 Joseph SB, Abrahams MR, Moeser M, Tyers L, Archin NM, Council OD, Sondgeroth A, Spielvogel E, Emery A, Zhou S, Doolabh D, Ismail SD, Karim SA, Margolis DM, Pond SK, ... ... Swanstrom R, et al. The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus. Plos Pathogens. 20: e1011974. PMID 38422171 DOI: 10.1371/journal.ppat.1011974  0.39
2023 Zhou S, Long N, Swanstrom R. Evolution Driven By A Varying Host Environment Selects For Distinct HIV-1 Entry Phenotypes and Other Informative Variants. Frontiers in Virology (Lausanne, Switzerland). 3. PMID 38239974 DOI: 10.3389/fviro.2023.1291996  0.501
2023 Zhou S, Long N, Moeser M, Hill CS, Samoff E, Mobley V, Frost S, Bayer C, Kelly E, Greifinger A, Shone S, Glover W, Clark M, Eron J, Cohen M, ... Swanstrom R, et al. Use of Next Generation Sequencing in a State-Wide Strategy of HIV-1 Surveillance: Impact of the SARS-CoV-2 Pandemic on HIV-1 Diagnosis and Transmission. The Journal of Infectious Diseases. PMID 37283544 DOI: 10.1093/infdis/jiad211  0.441
2023 Lockbaum GJ, Rusere LN, Henes M, Kosovrasti K, Rao DN, Spielvogel E, Lee SK, Nalivaika EA, Swanstrom R, Yilmaz NK, Schiffer CA, Ali A. HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues. European Journal of Medicinal Chemistry. 257: 115501. PMID 37244161 DOI: 10.1016/j.ejmech.2023.115501  0.318
2023 Emery A, Joseph SB, Swanstrom R. Nonsuppressible viremia during HIV-1 therapy meets molecular virology. The Journal of Clinical Investigation. 133. PMID 36919694 DOI: 10.1172/JCI167925  0.465
2023 Kincer LP, Schnell G, Swanstrom R, Miller MB, Spudich S, Eron JJ, Price RW, Joseph SB. HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells. Pathogens & Immunity. 7: 131-142. PMID 36865569 DOI: 10.20411/pai.v7i2.524  0.762
2023 Kincer LP, Joseph SB, Gilleece MM, Hauser BM, Sizemore S, Zhou S, Di Germanio C, Zetterberg H, Fuchs D, Deeks SG, Spudich S, Gisslen M, Price RW, Swanstrom R. Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus. Nature Microbiology. 8: 260-271. PMID 36717718 DOI: 10.1038/s41564-022-01306-6  0.472
2022 Zhou S, Hill CS, Spielvogel E, Clark MU, Hudgens MG, Swanstrom R. Unique Molecular Identifiers and Multiplexing Amplicons Maximize the Utility of Deep Sequencing To Critically Assess Population Diversity in RNA Viruses. Acs Infectious Diseases. PMID 36326446 DOI: 10.1021/acsinfecdis.2c00319  0.32
2022 Woodburn BM, Kanchi K, Zhou S, Colaianni N, Joseph SB, Swanstrom R. Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation. Journal of Virology. e0095722. PMID 35975998 DOI: 10.1128/jvi.00957-22  0.413
2022 Chiu LY, Emery A, Jain N, Sugarman A, Kendrick N, Luo L, Ford W, Swanstrom R, Tolbert BS. Encoded Conformational Dynamics of the HIV Splice Site A3 Regulatory Locus: Implications for Differential Binding of hnRNP Splicing Auxiliary Factors. Journal of Molecular Biology. 167728. PMID 35870649 DOI: 10.1016/j.jmb.2022.167728  0.353
2022 Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, ... ... Swanstrom R, et al. Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo. The Journal of Clinical Investigation. 132. PMID 35426377 DOI: 10.1172/JCI157281  0.462
2021 Ismail SD, Riou C, Joseph SB, Archin NM, Margolis DM, Perelson AS, Cassidy T, Abrahams MR, Moeser M, Council OD, McKinnon LR, Osman F, Abdool Karim Q, Abdool Karim SS, Swanstrom R, et al. Immunological correlates of the HIV-1 replication-competent reservoir size. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34181706 DOI: 10.1093/cid/ciab587  0.386
2021 Tsai K, Bogerd HP, Kennedy EM, Emery A, Swanstrom R, Cullen BR. Epitranscriptomic addition of mA regulates HIV-1 RNA stability and alternative splicing. Genes & Development. PMID 34140354 DOI: 10.1101/gad.348508.121  0.382
2021 Emery A, Swanstrom R. HIV-1: To Splice or Not to Splice, That Is the Question. Viruses. 13. PMID 33530363 DOI: 10.3390/v13020181  0.366
2020 Warren JA, Zhou S, Xu Y, Moeser MJ, MacMillan DR, Council O, Kirchherr J, Sung JM, Roan N, Adimora AA, Joseph S, Kuruc JD, Gay CL, Margolis DM, Archin N, ... ... Swanstrom R, et al. The HIV-1 latent reservoir is largely sensitive to circulating T cells. Elife. 9. PMID 33021198 DOI: 10.7554/eLife.57246  0.42
2020 Carbaugh DL, Zhou S, Sanders W, Moorman NJ, Swanstrom R, Lazear HM. Two genetic differences between closely-related Zika virus strains determine pathogenic outcome in mice. Journal of Virology. PMID 32796074 DOI: 10.1128/Jvi.00618-20  0.308
2020 Zhou S, Swanstrom R. Fact and Fiction about 1%: Next Generation Sequencing and the Detection of Minor Drug Resistant Variants in HIV-1 Populations with and without Unique Molecular Identifiers. Viruses. 12. PMID 32759675 DOI: 10.3390/V12080850  0.438
2020 Rusere LN, Lockbaum GJ, Henes M, Lee SK, Spielvogel E, Rao DN, Kosovrasti K, Nalivaika EA, Swanstrom R, Kurt Yilmaz N, Schiffer CA, Ali A. Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-Tetrahydrofuran in a Pseudo-Symmetric Dipeptide Isostere. Journal of Medicinal Chemistry. PMID 32672965 DOI: 10.1021/Acs.Jmedchem.0C00529  0.457
2020 Zhou S, Sizemore S, Moeser M, Zimmerman S, Samoff E, Mobley V, Frost S, Cressman A, Clark M, Skelly T, Kelkar H, Veluvolu U, Jones C, Eron J, Cohen M, ... ... Swanstrom R, et al. Near Real-Time Identification of Recent HIV Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by MPID-NGS in North Carolina. The Journal of Infectious Diseases. PMID 32663847 DOI: 10.1093/Infdis/Jiaa417  0.532
2020 Parkin NT, Avila-Rios S, Bibby DF, Brumme CJ, Eshleman SH, Harrigan PR, Howison M, Hunt G, Ji H, Kantor R, Ledwaba J, Lee ER, Matías-Florentino M, Mbisa JL, Noguera-Julian M, ... ... Swanstrom R, et al. Multi-Laboratory Comparison of Next-Generation to Sanger-Based Sequencing for HIV-1 Drug Resistance Genotyping. Viruses. 12. PMID 32605062 DOI: 10.3390/V12070694  0.457
2020 Tomezsko PJ, Corbin VDA, Gupta P, Swaminathan H, Glasgow M, Persad S, Edwards MD, Mcintosh L, Papenfuss AT, Emery A, Swanstrom R, Zang T, Lan TCT, Bieniasz P, Kuritzkes DR, et al. Determination of RNA structural diversity and its role in HIV-1 RNA splicing. Nature. 582: 438-442. PMID 32555469 DOI: 10.1038/S41586-020-2253-5  0.478
2020 Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR. Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability. Cell Host & Microbe. PMID 32533923 DOI: 10.1016/J.Chom.2020.05.011  0.54
2020 Ávila-Ríos S, Parkin N, Swanstrom R, Paredes R, Shafer R, Ji H, Kantor R. Next-Generation Sequencing for HIV Drug Resistance Testing: Laboratory, Clinical, and Implementation Considerations. Viruses. 12. PMID 32516949 DOI: 10.3390/V12060617  0.422
2020 Council OD, Zhou S, McCann CD, Hoffman I, Tegha G, Kamwendo D, Matoga M, Kosakovsky Pond SL, Cohen MS, Swanstrom R. Deep Sequencing Reveals Compartmentalized HIV-1 in the Semen of Men With and Without STI-Associated Urethritis. Journal of Virology. PMID 32269129 DOI: 10.1128/Jvi.00151-20  0.572
2020 Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, ... ... Swanstrom R, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Science Translational Medicine. PMID 32253226 DOI: 10.1126/Scitranslmed.Abb5883  0.352
2020 Margolis DM, Archin NM, Cohen MS, Eron JJ, Ferrari G, Garcia JV, Gay CL, Goonetilleke N, Joseph SB, Swanstrom R, Turner AW, Wahl A. Curing HIV: Seeking to Target and Clear Persistent Infection. Cell. PMID 32220311 DOI: 10.1016/J.Cell.2020.03.005  0.558
2020 Adewumi OM, Dukhovlinova E, Shehu NY, Zhou S, Council O, Akanbi MO, Taiwo B, Ogunniyi A, Robertson K, Kanyama C, Hosseinipour M, Swanstrom R. HIV-1 CNS COMPARTMENTALIZATION AND CYTOKINE INTERPLAY IN NON-SUBTYPE B HIV-1 INFECTIONS IN NIGERIA AND MALAWI. Aids Research and Human Retroviruses. PMID 31914800 DOI: 10.1089/Aid.2019.0245  0.561
2019 Abrahams MR, Joseph SB, Garrett N, Tyers L, Moeser M, Archin N, Council OD, Matten D, Zhou S, Doolabh D, Anthony C, Goonetilleke N, Karim SA, Margolis DM, Pond SK, ... ... Swanstrom R, et al. The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation. Science Translational Medicine. 11. PMID 31597754 DOI: 10.1126/scitranslmed.aaw5589  0.418
2019 Nelson JAE, de Paris K, Ramirez C, Edmonds A, Mollan KR, Bay CP, Compliment K, Herold BC, Anastos K, Minkoff H, Kassaye S, Seidman DL, French AL, Golub ET, Sheth AN, ... ... Swanstrom R, et al. Female genital tract shedding of HIV-1 is rare in women with suppressed HIV-1 in plasma. Aids (London, England). PMID 31483374 DOI: 10.1097/Qad.0000000000002373  0.489
2019 Courtney DG, Tsai K, Bogerd HP, Kennedy EM, Law BA, Emery A, Swanstrom R, Holley CL, Cullen BR. Epitranscriptomic Addition of mC to HIV-1 Transcripts Regulates Viral Gene Expression. Cell Host & Microbe. 26: 217-227.e6. PMID 31415754 DOI: 10.1016/J.Chom.2019.07.005  0.493
2019 Kutluay SB, Emery A, Penumutchu S, Townsend D, Tenneti K, Madison MK, Stukenbroeker AM, Powell C, Jannain D, Tolbert BS, Swanstrom RI, Bieniasz PD. Genome wide analysis of hnRNP binding to HIV-1 RNA reveals a key role for hnRNP H1 in alternative viral mRNA splicing. Journal of Virology. PMID 31413137 DOI: 10.1128/Jvi.01048-19  0.473
2019 Rusere LN, Lockbaum GJ, Lee SK, Henes M, Kosovrasti K, Spielvogel E, Nalivaika EA, Swanstrom R, Kurt Yilmaz N, Schiffer CA, Ali A. HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands to Optimize Hydrogen Bonding in the Substrate Envelope. Journal of Medicinal Chemistry. PMID 31386368 DOI: 10.1021/Acs.Jmedchem.9B00838  0.393
2019 Henes M, Lockbaum GJ, Kosovrasti K, Leidner F, Nachum GS, Nalivaika EA, Lee SK, Spielvogel E, Zhou S, Swanstrom R, Bolon DNA, Kurt Yilmaz N, Schiffer CA. pM to µM - Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance. Acs Chemical Biology. PMID 31361460 DOI: 10.1021/Acschembio.9B00370  0.382
2019 Zhu C, Dukhovlinova E, Council O, Ping L, Faison EM, Prabhu SS, Potter EL, Upton SL, Yin G, Fay JM, Kincer LP, Spielvogel E, Campbell SL, Benhabbour SR, Ke H, ... Swanstrom R, et al. Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies. Nature Communications. 10: 948. PMID 30814513 DOI: 10.1038/S41467-019-08876-W  0.415
2019 Boucher JI, Whitfield TW, Dauphin A, Nachum G, Hollins C, Zeldovich KB, Swanstrom R, Schiffer CA, Luban J, Bolon DNA. Constrained mutational sampling of amino acids in HIV-1 protease evolution. Molecular Biology and Evolution. PMID 30721995 DOI: 10.1093/Molbev/Msz022  0.453
2019 Srinivas N, Joseph SB, Robertson K, Kincer LP, Menezes P, Adamson L, Schauer AP, Blake KH, White N, Sykes C, Luciw P, Eron JJ, Forrest A, Price R, Spudich S, ... Swanstrom R, et al. Predicting efavirenz concentrations in the brain tissue of HIV-infected individuals and exploring their relationship to neurocognitive impairment. Clinical and Translational Science. PMID 30675981 DOI: 10.1111/Cts.12620  0.356
2018 Joseph SB, Kincer LP, Bowman NM, Evans C, Vinikoor MJ, Lippincott CK, Gisslén M, Spudich S, Menezes P, Robertson K, Archin N, Kashuba A, Eron JJ, Price RW, Swanstrom R. HIV-1 RNA Detected in the CNS after Years of Suppressive Antiretroviral Therapy Can Originate from a Replicating CNS Reservoir or Clonally Expanded Cells. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30561541 DOI: 10.1093/Cid/Ciy1066  0.488
2018 Zhou S, Williford SE, McGivern DR, Burch CL, Hu F, Benzine T, Ingravallo P, Asante-Appiah E, Howe AYM, Swanstrom R, Lemon SM. Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus. Antiviral Research. PMID 30081054 DOI: 10.1016/J.Antiviral.2018.07.024  0.398
2018 Dennis AM, Zhou S, Sellers CJ, Learner E, Potempa M, Cohen MS, Miller WC, Eron JJ, Swanstrom R. Using Primer-ID Deep Sequencing to Detect Recent HIV-1 Infection. The Journal of Infectious Diseases. PMID 30010965 DOI: 10.1093/Infdis/Jiy426  0.416
2018 Dukhovlinova E, Masharsky A, Vasileva A, Porrello A, Zhou S, Toussova O, Verevochkin S, Akulova E, Frishman D, Montefiori D, Labranche C, Hoffman I, Miller W, Cohen MS, Kozlov A, ... Swanstrom R, et al. Characterization of the Transmitted Virus in an Ongoing HIV-1 Epidemic Driven by Injecting Drug Use. Aids Research and Human Retroviruses. PMID 29756455 DOI: 10.1089/Aid.2017.0313  0.595
2018 Swanstrom R, Joseph SB. Editorial: The HIV/SIV Envelope Protein: From Structure To Function To Host Evasion. Current Hiv Research. 16: 3-4. PMID 29708481 DOI: 10.2174/1570162X1601180419095704  0.49
2018 Joseph SB, Swanstrom R. The evolution of HIV-1 entry phenotypes as a guide to changing target cells. Journal of Leukocyte Biology. PMID 29389021 DOI: 10.1002/Jlb.2Ri0517-200R  0.458
2018 Takata MA, Soll SJ, Emery A, Blanco-Melo D, Swanstrom R, Bieniasz PD. Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication. Plos Pathogens. 14: e1006824. PMID 29377940 DOI: 10.1371/Journal.Ppat.1006824  0.493
2017 Rademeyer C, Korber B, Seaman MS, Giorgi EE, Thebus R, Robles A, Sheward DJ, Wagh K, Garrity J, Carey BR, Gao H, Greene KM, Tang H, Bandawe GP, Marais JC, ... ... Swanstrom R, et al. Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. Plos Pathogens. 13: e1006641. PMID 28945784 DOI: 10.1371/journal.ppat.1006641  0.325
2017 Clutter DS, Zhou S, Varghese V, Rhee SY, Pinsky BA, Jeffrey Fessel W, Klein DB, Spielvogel E, Holmes SP, Hurley LB, Silverberg MJ, Swanstrom R, Shafer RW. Prevalence of Drug-Resistant Minority Variants in Untreated HIV-1-Infected Individuals With and Those Without Transmitted Drug Resistance Detected by Sanger Sequencing. The Journal of Infectious Diseases. 216: 387-391. PMID 28859436 DOI: 10.1093/Infdis/Jix338  0.408
2017 Swanstrom R, Graham WD, Zhou S. Sequencing the Biology of Entry: The Retroviral env Gene. Current Topics in Microbiology and Immunology. PMID 28688086 DOI: 10.1007/82_2017_35  0.558
2017 Emery A, Zhou S, Pollom E, Swanstrom R. Characterizing HIV-1 Splicing Using Next Generation Sequencing. Journal of Virology. PMID 28077653 DOI: 10.1128/Jvi.02515-16  0.785
2016 Joseph J, Cinque P, Colosi D, Dravid A, Ene L, Fox H, Gabuzda D, Gisslen M, Beth Joseph S, Letendre S, Mukerji SS, Nath A, Perez-Valero I, Persaud D, Price RW, ... ... Swanstrom R, et al. Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA. Journal of Virus Eradication. 2: 243-250. PMID 27781109  0.427
2016 Lee SK, Zhou S, Baldoni PL, Spielvogel E, Archin NM, Hudgens MG, Margolis DM, Swanstrom R. Quantification of the Latent HIV-1 Reservoir Using Ultra Deep Sequencing and Primer ID In A Viral Outgrowth Assay. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27683060 DOI: 10.1097/Qai.0000000000001187  0.588
2016 Eshleman SH, Hudelson SE, Redd AD, Swanstrom R, Ou SS, Zhang XC, Ping LH, Piwowar-Manning E, Porcella SF, Sievers MF, Martens CA, Bruno D, Dukhovlinova E, McCauley M, Gamble T, et al. Treatment as Prevention: Characterization of partner infections in the HIV Prevention Trials Network 052 trial. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27532476 DOI: 10.1097/Qai.0000000000001158  0.507
2016 Zambonelli C, Dey AK, Hilt S, Stephenson S, Go EP, Clark DF, Wininger M, Labranche C, Montefiori D, Liao HX, Swanstrom RI, Desaire H, Haynes BF, Carfi A, Barnett SW. Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa. Plos One. 11: e0157391. PMID 27442017 DOI: 10.1371/Journal.Pone.0157391  0.372
2016 Rademeyer C, Korber B, Seaman MS, Giorgi EE, Thebus R, Robles A, Sheward DJ, Wagh K, Garrity J, Carey BR, Gao H, Greene KM, Tang H, Bandawe GP, Marais JC, ... ... Swanstrom R, et al. Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. Plos Pathogens. 12: e1005742. PMID 27434311 DOI: 10.1371/Journal.Ppat.1005742  0.482
2016 Lewis CA, Crayle J, Zhou S, Swanstrom R, Wolfenden R. Cytosine deamination and the precipitous decline of spontaneous mutation during Earth's history. Proceedings of the National Academy of Sciences of the United States of America. PMID 27382162 DOI: 10.1073/Pnas.1607580113  0.312
2016 Zhou S, Bednar MM, Sturdevant CB, Hauser BM, Swanstrom R. Deep Sequencing of the HIV-1 env Gene Reveals Discrete X4 Lineages and Linkage Disequilibrium Between X4 and R5 Viruses In the V1/V2 and V3 Variable Regions. Journal of Virology. PMID 27226378 DOI: 10.1128/Jvi.00441-16  0.814
2016 Bednar MM, Hauser BM, Zhou S, Jacobson JM, Eron JJ, Frank I, Swanstrom R. Diversity and Tropism of HIV-1 Plasma Rebound Virus after Treatment Discontinuation. The Journal of Infectious Diseases. PMID 27132284 DOI: 10.1093/Infdis/Jiw172  0.527
2016 Clutter D, Zhou S, Varghese V, Rhee S, Pinsky B, Fessel WJ, Klein D, Hurley L, Silverberg M, Swanstrom R, Shafer R. Prevalence and Clinical Implications of Minority Variant (MV) Human Immunodeficiency Virus (HIV) Drug-Resistance Mutations (DRMs) in Antiretroviral (ARV)-Naive Patients With and Without Transmitted Drug Resistance (TDR) Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw194.167  0.464
2015 Dara J, Dow A, Cromwell E, Sturdevant CB, Mallewa M, Swanstrom R, Van Rie A, Prasad VR. Multivariable analysis to determine if HIV-1 Tat dicysteine motif is associated with neurodevelopmental delay in HIV-infected children in Malawi. Behavioral and Brain Functions : Bbf. 11: 38. PMID 26678821 DOI: 10.1186/S12993-015-0083-7  0.838
2015 Churchill MJ, Deeks SG, Margolis DM, Siliciano RF, Swanstrom R. HIV reservoirs: what, where and how to target them. Nature Reviews. Microbiology. PMID 26616417 DOI: 10.1038/Nrmicro.2015.5  0.509
2015 Arrildt KT, LaBranche CC, Joseph SB, Dukhovlinova EN, Graham WD, Ping LH, Schnell G, Sturdevant CB, Kincer LP, Mallewa M, Heyderman RS, Van Rie A, Cohen MS, Spudich S, Price RW, ... ... Swanstrom R, et al. Phenotypic Correlates of HIV-1 Macrophage Tropism. Journal of Virology. PMID 26339058 DOI: 10.1128/Jvi.00946-15  0.813
2015 Bednar MM, Hauser BM, Ping LH, Dukhovlinova E, Zhou S, Arrildt KT, Hoffman IF, Eron JJ, Cohen MS, Swanstrom R. R5 Macrophage-Tropic HIV-1 in the Male Genital Tract. Journal of Virology. 89: 10688-92. PMID 26223642 DOI: 10.1128/Jvi.01842-15  0.515
2015 Joseph SB, Swanstrom R, Kashuba AD, Cohen MS. Bottlenecks in HIV-1 transmission: insights from the study of founder viruses. Nature Reviews. Microbiology. 13: 414-25. PMID 26052661 DOI: 10.1038/nrmicro3471  0.466
2015 Cope AB, Powers KA, Kuruc JD, Leone PA, Anderson JA, Ping LH, Kincer LP, Swanstrom R, Mobley VL, Foust E, Gay CL, Eron JJ, Cohen MS, Miller WC. Ongoing HIV Transmission and the HIV Care Continuum in North Carolina. Plos One. 10: e0127950. PMID 26042804 DOI: 10.1371/Journal.Pone.0127950  0.492
2015 Zhou S, Jones C, Mieczkowski P, Swanstrom R. Primer ID Validates Template Sampling Depth and Greatly Reduces the Error Rate of Next-Generation Sequencing of HIV-1 Genomic RNA Populations. Journal of Virology. 89: 8540-55. PMID 26041299 DOI: 10.1128/Jvi.00522-15  0.404
2015 Potempa M, Nalivaika E, Ragland D, Lee SK, Schiffer CA, Swanstrom R. A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro. Journal of Molecular Biology. 427: 2360-78. PMID 25986307 DOI: 10.1016/J.Jmb.2015.05.007  0.506
2015 Bednar MM, Sturdevant CB, Tompkins LA, Arrildt KT, Dukhovlinova E, Kincer LP, Swanstrom R. Compartmentalization, Viral Evolution, and Viral Latency of HIV in the CNS. Current Hiv/Aids Reports. 12: 262-71. PMID 25914150 DOI: 10.1007/S11904-015-0265-9  0.84
2015 Sturdevant CB, Joseph SB, Schnell G, Price RW, Swanstrom R, Spudich S. Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection. Plos Pathogens. 11: e1004720. PMID 25811757 DOI: 10.1371/Journal.Ppat.1004720  0.843
2015 Potempa M, Lee SK, Wolfenden R, Swanstrom R. The triple threat of HIV-1 protease inhibitors. Current Topics in Microbiology and Immunology. 389: 203-41. PMID 25778681 DOI: 10.1007/82_2015_438  0.543
2015 Williamson C, Swanstrom R. HIV-1 replication capacity: Setting the pace of disease. Proceedings of the National Academy of Sciences of the United States of America. 112: 3591-2. PMID 25775570 DOI: 10.1073/pnas.1502208112  0.404
2015 Keys JR, Zhou S, Anderson JA, Eron JJ, Rackoff LA, Jabara C, Swanstrom R. Primer ID Informs Next-Generation Sequencing Platforms and Reveals Preexisting Drug Resistance Mutations in the HIV-1 Reverse Transcriptase Coding Domain. Aids Research and Human Retroviruses. 31: 658-68. PMID 25748056 DOI: 10.1089/Aid.2014.0031  0.443
2015 Joseph SB, Arrildt KT, Sturdevant CB, Swanstrom R. HIV-1 target cells in the CNS. Journal of Neurovirology. 21: 276-89. PMID 25236812 DOI: 10.1007/S13365-014-0287-X  0.838
2014 Joseph SB, Lee B, Swanstrom R. Affinofile Assay for Identifying Macrophage-Tropic HIV-1. Bio-Protocol. 4. PMID 29552584 DOI: 10.21769/BioProtoc.1184  0.431
2014 Hraber P, Korber BT, Lapedes AS, Bailer RT, Seaman MS, Gao H, Greene KM, McCutchan F, Williamson C, Kim JH, Tovanabutra S, Hahn BH, Swanstrom R, Thomson MM, Gao F, et al. Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies. Journal of Virology. 88: 12623-43. PMID 25142591 DOI: 10.1128/Jvi.01705-14  0.507
2014 Jabara CB, Hu F, Mollan KR, Williford SE, Menezes P, Yang Y, Eron JJ, Fried MW, Hudgens MG, Jones CD, Swanstrom R, Lemon SM. Hepatitis C Virus (HCV) NS3 sequence diversity and antiviral resistance-associated variant frequency in HCV/HIV coinfection. Antimicrobial Agents and Chemotherapy. 58: 6079-92. PMID 25092699 DOI: 10.1128/Aac.03466-14  0.381
2014 Joseph SB, Swanstrom R. HIV/AIDS. A fitness bottleneck in HIV-1 transmission. Science (New York, N.Y.). 345: 136-7. PMID 25013044 DOI: 10.1126/Science.1257425  0.555
2014 Price RW, Spudich SS, Peterson J, Joseph S, Fuchs D, Zetterberg H, Gisslén M, Swanstrom R. Evolving character of chronic central nervous system HIV infection. Seminars in Neurology. 34: 7-13. PMID 24715483 DOI: 10.1055/S-0034-1372337  0.51
2014 Joseph SB, Arrildt KT, Swanstrom AE, Schnell G, Lee B, Hoxie JA, Swanstrom R. Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities. Journal of Virology. 88: 1858-69. PMID 24307580 DOI: 10.1128/Jvi.02477-13  0.768
2014 Keys JR, Leone PA, Eron JJ, Alexander K, Brinson M, Swanstrom R. Large scale screening of human sera for HCV RNA and GBV-C RNA. Journal of Medical Virology. 86: 473-7. PMID 24178362 DOI: 10.1002/Jmv.23829  0.456
2013 Alexander J, Mendy J, Vang L, Avanzini JB, Garduno F, Manayani DJ, Ishioka G, Farness P, Ping LH, Swanstrom R, Parks R, Liao HX, Haynes BF, Montefiori DC, LaBranche C, et al. Pre-clinical development of a recombinant, replication-competent adenovirus serotype 4 vector vaccine expressing HIV-1 envelope 1086 clade C. Plos One. 8: e82380. PMID 24312658 DOI: 10.1371/Journal.Pone.0082380  0.47
2013 Cheng N, Lee SK, Donover PS, Reichman M, Schiffer CA, Hull-Ryde EA, Swanstrom R, Janzen WP. Development of a Novel Screening Strategy Designed to Discover a New Class of HIV Drugs. Journal of Laboratory Automation. 19: 297-303. PMID 24305957 DOI: 10.1177/2211068213513453  0.438
2013 Ping LH, Jabara CB, Rodrigo AG, Hudelson SE, Piwowar-Manning E, Wang L, Eshleman SH, Cohen MS, Swanstrom R. HIV-1 transmission during early antiretroviral therapy: evaluation of two HIV-1 transmission events in the HPTN 052 prevention study. Plos One. 8: e71557. PMID 24086252 DOI: 10.1371/Journal.Pone.0071557  0.538
2013 Lee SK, Cheng N, Hull-Ryde E, Potempa M, Schiffer CA, Janzen W, Swanstrom R. A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsid. Biochemistry. 52: 4929-40. PMID 23763575 DOI: 10.1021/Bi4005232  0.353
2013 Potempa M, Swanstrom R. Integrating the HIV-1 assembly/maturation pathway. Proceedings of the National Academy of Sciences of the United States of America. 110: 8327-8. PMID 23671082 DOI: 10.1073/Pnas.1306620110  0.491
2013 Ping LH, Joseph SB, Anderson JA, Abrahams MR, Salazar-Gonzalez JF, Kincer LP, Treurnicht FK, Arney L, Ojeda S, Zhang M, Keys J, Potter EL, Chu H, Moore P, Salazar MG, ... ... Swanstrom R, et al. Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design. Journal of Virology. 87: 7218-33. PMID 23616655 DOI: 10.1128/Jvi.03577-12  0.506
2013 Pollom E, Dang KK, Potter EL, Gorelick RJ, Burch CL, Weeks KM, Swanstrom R. Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs. Plos Pathogens. 9: e1003294. PMID 23593004 DOI: 10.1371/Journal.Ppat.1003294  0.792
2013 Liao HX, Tsao CY, Alam SM, Muldoon M, Vandergrift N, Ma BJ, Lu X, Sutherland LL, Scearce RM, Bowman C, Parks R, Chen H, Blinn JH, Lapedes A, Watson S, ... ... Swanstrom R, et al. Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1. Journal of Virology. 87: 4185-201. PMID 23365441 DOI: 10.1128/Jvi.02297-12  0.367
2013 Fouda GG, Mahlokozera T, Salazar-Gonzalez JF, Salazar MG, Learn G, Kumar SB, Dennison SM, Russell E, Rizzolo K, Jaeger F, Cai F, Vandergrift NA, Gao F, Hahn B, Shaw GM, ... ... Swanstrom R, et al. Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants. Retrovirology. 10: 3. PMID 23305422 DOI: 10.1186/1742-4690-10-3  0.695
2013 Coffin J, Swanstrom R. HIV pathogenesis: dynamics and genetics of viral populations and infected cells. Cold Spring Harbor Perspectives in Medicine. 3: a012526. PMID 23284080 DOI: 10.1101/Cshperspect.A012526  0.556
2013 Liu MK, Hawkins N, Ritchie AJ, Ganusov VV, Whale V, Brackenridge S, Li H, Pavlicek JW, Cai F, Rose-Abrahams M, Treurnicht F, Hraber P, Riou C, Gray C, Ferrari G, ... ... Swanstrom R, et al. Vertical T cell immunodominance and epitope entropy determine HIV-1 escape. The Journal of Clinical Investigation. 123: 380-93. PMID 23221345 DOI: 10.1172/Jci65330  0.522
2013 Russell ES, Ojeda S, Fouda GG, Meshnick SR, Montefiori D, Permar SR, Swanstrom R. Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes. Aids Research and Human Retroviruses. 29: 511-5. PMID 23075434 DOI: 10.1089/Aid.2012.0197  0.706
2012 Sturdevant CB, Dow A, Jabara CB, Joseph SB, Schnell G, Takamune N, Mallewa M, Heyderman RS, Van Rie A, Swanstrom R. Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children. Plos Pathogens. 8: e1003094. PMID 23300446 DOI: 10.1371/Journal.Ppat.1003094  0.834
2012 Swanstrom R, Coffin J. HIV-1 pathogenesis: the virus. Cold Spring Harbor Perspectives in Medicine. 2: a007443. PMID 23143844 DOI: 10.1101/Cshperspect.A007443  0.454
2012 Moore PL, Gray ES, Wibmer CK, Bhiman JN, Nonyane M, Sheward DJ, Hermanus T, Bajimaya S, Tumba NL, Abrahams MR, Lambson BE, Ranchobe N, Ping L, Ngandu N, Abdool Karim Q, ... ... Swanstrom RI, et al. Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape. Nature Medicine. 18: 1688-92. PMID 23086475 DOI: 10.1038/Nm.2985  0.318
2012 Lee SK, Potempa M, Swanstrom R. The choreography of HIV-1 proteolytic processing and virion assembly. The Journal of Biological Chemistry. 287: 40867-74. PMID 23043111 DOI: 10.1074/Jbc.R112.399444  0.443
2012 Price RW, Swanstrom R. Targeting chronic central nervous system HIV infection. Antiviral Therapy. 17: 1227-31. PMID 23018178 DOI: 10.3851/Imp2414  0.447
2012 Valley-Omar Z, Sibeko S, Anderson J, Goodier S, Werner L, Arney L, Naranbhai V, Treurnicht F, Abrahams MR, Bandawe G, Swanstrom R, Karim QA, Karim SS, Williamson C. CAPRISA 004 tenofovir microbicide trial: no impact of tenofovir gel on the HIV transmission bottleneck. The Journal of Infectious Diseases. 206: 35-40. PMID 22551813 DOI: 10.1093/Infdis/Jis305  0.348
2012 Lee SK, Potempa M, Kolli M, Özen A, Schiffer CA, Swanstrom R. Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease. The Journal of Biological Chemistry. 287: 13279-90. PMID 22334652 DOI: 10.1074/Jbc.M112.339374  0.329
2012 Arrildt KT, Joseph SB, Swanstrom R. The HIV-1 env protein: a coat of many colors. Current Hiv/Aids Reports. 9: 52-63. PMID 22237899 DOI: 10.1007/S11904-011-0107-3  0.563
2012 Henderson GJ, Lee SK, Irlbeck DM, Harris J, Kline M, Pollom E, Parkin N, Swanstrom R. Interplay between single resistance-associated mutations in the HIV-1 protease and viral infectivity, protease activity, and inhibitor sensitivity. Antimicrobial Agents and Chemotherapy. 56: 623-33. PMID 22083488 DOI: 10.1128/AAC.05549-11  0.779
2011 Jabara CB, Jones CD, Roach J, Anderson JA, Swanstrom R. Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID. Proceedings of the National Academy of Sciences of the United States of America. 108: 20166-71. PMID 22135472 DOI: 10.1073/Pnas.1110064108  0.406
2011 Schnell G, Joseph S, Spudich S, Price RW, Swanstrom R. HIV-1 replication in the central nervous system occurs in two distinct cell types. Plos Pathogens. 7: e1002286. PMID 22007152 DOI: 10.1371/Journal.Ppat.1002286  0.803
2011 Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, ... Swanstrom R, et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. Plos Pathogens. 7: e1002209. PMID 21980282 DOI: 10.1371/Journal.Ppat.1002209  0.448
2011 Russell ES, Kwiek JJ, Keys J, Barton K, Mwapasa V, Montefiori DC, Meshnick SR, Swanstrom R. The genetic bottleneck in vertical transmission of subtype C HIV-1 is not driven by selection of especially neutralization-resistant virus from the maternal viral population. Journal of Virology. 85: 8253-62. PMID 21593171 DOI: 10.1128/Jvi.00197-11  0.683
2011 Gay C, Dibben O, Anderson JA, Stacey A, Mayo AJ, Norris PJ, Kuruc JD, Salazar-Gonzalez JF, Li H, Keele BF, Hicks C, Margolis D, Ferrari G, Haynes B, Swanstrom R, et al. Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy. Plos One. 6: e19617. PMID 21573003 DOI: 10.1371/Journal.Pone.0019617  0.525
2011 Anderson JA, Archin NM, Ince W, Parker D, Wiegand A, Coffin JM, Kuruc J, Eron J, Swanstrom R, Margolis DM. Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells. Journal of Virology. 85: 5220-3. PMID 21367910 DOI: 10.1128/Jvi.00284-11  0.814
2010 Anderson JA, Ping LH, Dibben O, Jabara CB, Arney L, Kincer L, Tang Y, Hobbs M, Hoffman I, Kazembe P, Jones CD, Borrow P, Fiscus S, Cohen MS, Swanstrom R, et al. HIV-1 Populations in Semen Arise through Multiple Mechanisms. Plos Pathogens. 6: e1001053. PMID 20808902 DOI: 10.1371/Journal.Ppat.1001053  0.479
2010 Masharsky AE, Dukhovlinova EN, Verevochkin SV, Toussova OV, Skochilov RV, Anderson JA, Hoffman I, Cohen MS, Swanstrom R, Kozlov AP. A substantial transmission bottleneck among newly and recently HIV-1-infected injection drug users in St Petersburg, Russia. The Journal of Infectious Diseases. 201: 1697-702. PMID 20423223 DOI: 10.1086/652702  0.524
2010 Ince WL, Zhang L, Jiang Q, Arrildt K, Su L, Swanstrom R. Evolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse model. Journal of Virology. 84: 2740-52. PMID 20042504 DOI: 10.1128/Jvi.02180-09  0.794
2010 Schnell G, Price RW, Swanstrom R, Spudich S. Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection. Journal of Virology. 84: 2395-407. PMID 20015984 DOI: 10.1128/Jvi.01863-09  0.795
2010 Kraus MH, Parrish NF, Shaw KS, Decker JM, Keele BF, Salazar-Gonzalez JF, Grayson T, McPherson DT, Ping LH, Anderson JA, Swanstrom R, Williamson C, Shaw GM, Hahn BH. A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays. Virology. 397: 346-57. PMID 20003995 DOI: 10.1016/J.Virol.2009.11.019  0.502
2010 Schnell G, Joseph S, Spudich S, Price R, Swanstrom R. Where are macrophage-tropic viruses? Journal of the International Aids Society. 13: O3. DOI: 10.1186/1758-2652-13-S3-O3  0.771
2009 Watts JM, Dang KK, Gorelick RJ, Leonard CW, Bess JW, Swanstrom R, Burch CL, Weeks KM. Architecture and secondary structure of an entire HIV-1 RNA genome. Nature. 460: 711-6. PMID 19661910 DOI: 10.1038/Nature08237  0.403
2009 Lee SK, Harris J, Swanstrom R. A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle. Journal of Virology. 83: 8536-43. PMID 19515760 DOI: 10.1128/JVI.00317-09  0.348
2009 Choudhary SK, Rezk NL, Ince WL, Cheema M, Zhang L, Su L, Swanstrom R, Kashuba AD, Margolis DM. Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4+ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2-/-{gamma}c-/- mouse. Journal of Virology. 83: 8254-8. PMID 19494021 DOI: 10.1128/Jvi.00580-09  0.813
2009 Harrington PR, Schnell G, Letendre SL, Ritola K, Robertson K, Hall C, Burch CL, Jabara CB, Moore DT, Ellis RJ, Price RW, Swanstrom R. Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course. Aids (London, England). 23: 907-15. PMID 19414991 DOI: 10.1097/Qad.0B013E3283299129  0.761
2009 Schnell G, Spudich S, Harrington P, Price RW, Swanstrom R. Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1-associated dementia. Plos Pathogens. 5: e1000395. PMID 19390619 DOI: 10.1371/Journal.Ppat.1000395  0.774
2009 Ince WL, Harrington PR, Schnell GL, Patel-Chhabra M, Burch CL, Menezes P, Price RW, Eron JJ, Swanstrom RI. Major coexisting human immunodeficiency virus type 1 env gene subpopulations in the peripheral blood are produced by cells with similar turnover rates and show little evidence of genetic compartmentalization. Journal of Virology. 83: 4068-80. PMID 19211740 DOI: 10.1128/Jvi.02486-08  0.856
2009 Abrahams MR, Anderson JA, Giorgi EE, Seoighe C, Mlisana K, Ping LH, Athreya GS, Treurnicht FK, Keele BF, Wood N, Salazar-Gonzalez JF, Bhattacharya T, Chu H, Hoffman I, Galvin S, ... ... Swanstrom R, et al. Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. Journal of Virology. 83: 3556-67. PMID 19193811 DOI: 10.1128/Jvi.02132-08  0.32
2009 Anderson J, Schiffer C, Lee SK, Swanstrom R. Viral protease inhibitors. Handbook of Experimental Pharmacology. 85-110. PMID 19048198 DOI: 10.1007/978-3-540-79086-0_4  0.359
2009 Abrahams MR, Anderson JA, Giorgi EE, Seoighe C, Mlisana K, Ping LH, Athreya GS, Treurnicht FK, Keele BF, Wood N, Salazar-Gonzalez JF, Bhattacharya T, Chu H, Hoffman I, Galvin S, ... ... Swanstrom R, et al. Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants (Journal of Virology (2009) 83, 8, (3556-3567)) Journal of Virology. 83: 6974. DOI: 10.1128/Jvi.00832-09  0.309
2009 Swanstrom R. 109 Complexity of the Transmitted Virus and Compartmentalization In Its Seminal Source Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351066.51590.9F  0.325
2009 Swanstrom R. A Strong Dominant Negative Mutation in the HIV-1 Gag Protein Defines a New Drug Target Antiviral Research. 82: A43. DOI: 10.1016/J.Antiviral.2009.02.092  0.454
2008 Schnell G, Ince WL, Swanstrom R. Identification and recovery of minor HIV-1 variants using the heteroduplex tracking assay and biotinylated probes. Nucleic Acids Research. 36: e146. PMID 18948297 DOI: 10.1093/Nar/Gkn713  0.838
2008 Knies JL, Dang KK, Vision TJ, Hoffman NG, Swanstrom R, Burch CL. Compensatory evolution in RNA secondary structures increases substitution rate variation among sites. Molecular Biology and Evolution. 25: 1778-87. PMID 18535013 DOI: 10.1093/Molbev/Msn130  0.671
2008 Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, Sun C, Grayson T, Wang S, Li H, Wei X, Jiang C, Kirchherr JL, Gao F, Anderson JA, ... ... Swanstrom R, et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 105: 7552-7. PMID 18490657 DOI: 10.1073/Pnas.0802203105  0.498
2008 Anderson JA, Jiang H, Ding X, Petch L, Journigan T, Fiscus SA, Haubrich R, Katzenstein D, Swanstrom R, Gulick RM. Genotypic susceptibility scores and HIV type 1 RNA responses in treatment-experienced subjects with HIV type 1 infection. Aids Research and Human Retroviruses. 24: 685-94. PMID 18462083 DOI: 10.1089/Aid.2007.0127  0.458
2008 Kwiek JJ, Russell ES, Dang KK, Burch CL, Mwapasa V, Meshnick SR, Swanstrom R. The molecular epidemiology of HIV-1 envelope diversity during HIV-1 subtype C vertical transmission in Malawian mother-infant pairs. Aids (London, England). 22: 863-71. PMID 18427205 DOI: 10.1097/Qad.0B013E3282F51Ea0  0.646
2008 Salazar-Gonzalez JF, Bailes E, Pham KT, Salazar MG, Guffey MB, Keele BF, Derdeyn CA, Farmer P, Hunter E, Allen S, Manigart O, Mulenga J, Anderson JA, Swanstrom R, Haynes BF, et al. Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. Journal of Virology. 82: 3952-70. PMID 18256145 DOI: 10.1128/Jvi.02660-07  0.459
2008 Patel MB, Hoffman NG, Swanstrom R. Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins. Journal of Virology. 82: 903-16. PMID 18003735 DOI: 10.1128/Jvi.01444-07  0.727
2007 Harrington PR, Connell MJ, Meeker RB, Johnson PR, Swanstrom R. Dynamics of simian immunodeficiency virus populations in blood and cerebrospinal fluid over the full course of infection. The Journal of Infectious Diseases. 196: 1058-67. PMID 17763329 DOI: 10.1086/520819  0.351
2007 Resik S, Lemey P, Ping LH, Kouri V, Joanes J, Pérez J, Vandamme AM, Swanstrom R. Limitations to contact tracing and phylogenetic analysis in establishing HIV type 1 transmission networks in Cuba. Aids Research and Human Retroviruses. 23: 347-56. PMID 17411367 DOI: 10.1089/aid.2006.0158  0.316
2007 Cecil C, West A, Collier M, Jurgens C, Madden V, Whitmore A, Johnston R, Moore DT, Swanstrom R, Davis NL. Structure and immunogenicity of alternative forms of the simian immunodeficiency virus gag protein expressed using Venezuelan equine encephalitis virus replicon particles. Virology. 362: 362-73. PMID 17275057 DOI: 10.1016/J.Virol.2006.12.029  0.344
2006 Coetzer M, Cilliers T, Ping LH, Swanstrom R, Morris L. Genetic characteristics of the V3 region associated with CXCR4 usage in HIV-1 subtype C isolates. Virology. 356: 95-105. PMID 16942785 DOI: 10.1016/J.Virol.2006.07.030  0.466
2006 Foulkes JE, Prabu-Jeyabalan M, Cooper D, Henderson GJ, Harris J, Swanstrom R, Schiffer CA. Role of invariant Thr80 in human immunodeficiency virus type 1 protease structure, function, and viral infectivity. Journal of Virology. 80: 6906-16. PMID 16809296 DOI: 10.1128/Jvi.01900-05  0.848
2005 Ritola K, Robertson K, Fiscus SA, Hall C, Swanstrom R. Increased human immunodeficiency virus type 1 (HIV-1) env compartmentalization in the presence of HIV-1-associated dementia. Journal of Virology. 79: 10830-4. PMID 16051875 DOI: 10.1128/Jvi.79.16.10830-10834.2005  0.514
2005 Resch W, Parkin N, Watkins T, Harris J, Swanstrom R. Evolution of human immunodeficiency virus type 1 protease genotypes and phenotypes in vivo under selective pressure of the protease inhibitor ritonavir. Journal of Virology. 79: 10638-49. PMID 16051856 DOI: 10.1128/Jvi.79.16.10638-10649.2005  0.676
2005 Kitrinos KM, Nelson JA, Resch W, Swanstrom R. Effect of a protease inhibitor-induced genetic bottleneck on human immunodeficiency virus type 1 env gene populations. Journal of Virology. 79: 10627-37. PMID 16051855 DOI: 10.1128/Jvi.79.16.10627-10637.2005  0.721
2005 Johnston RE, Johnson PR, Connell MJ, Montefiori DC, West A, Collier ML, Cecil C, Swanstrom R, Frelinger JA, Davis NL. Vaccination of macaques with SIV immunogens delivered by Venezuelan equine encephalitis virus replicon particle vectors followed by a mucosal challenge with SIVsmE660. Vaccine. 23: 4969-79. PMID 16005121 DOI: 10.1016/J.Vaccine.2005.05.034  0.343
2005 Ngrenngarmlert W, Kwiek JJ, Kamwendo DD, Ritola K, Swanstrom R, Wongsrichanalai C, Miller RS, Ittarat W, Meshnick SR. Measuring allelic heterogeneity in Plasmodium falciparum by a heteroduplex tracking assay. The American Journal of Tropical Medicine and Hygiene. 72: 694-701. PMID 15964952 DOI: 10.4269/Ajtmh.2005.72.694  0.314
2005 Harrington PR, Haas DW, Ritola K, Swanstrom R. Compartmentalized human immunodeficiency virus type 1 present in cerebrospinal fluid is produced by short-lived cells. Journal of Virology. 79: 7959-66. PMID 15956542 DOI: 10.1128/Jvi.79.13.7959-7966.2005  0.523
2005 Walter BL, Wehrly K, Swanstrom R, Platt E, Kabat D, Chesebro B. Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophages. Journal of Virology. 79: 4828-37. PMID 15795268 DOI: 10.1128/Jvi.79.8.4828-4837.2005  0.451
2005 Cohen M, Pilcher C, Eron J, Leone P, Fiscus S, Swanstrom R. Retrovirology. 2: S57. DOI: 10.1186/1742-4690-2-S1-S57  0.566
2005 Hoffman NG, Schiffer CA, Swanstrom R. Erratum to “Covariation of amino acid positions in HIV-1 protease” [Virology 314 (2003) 536–548] Virology. 331: 206-207. DOI: 10.1016/J.Virol.2004.10.029  0.72
2004 Henderson GJ, Hoffman NG, Ping LH, Fiscus SA, Hoffman IF, Kitrinos KM, Banda T, Martinson FE, Kazembe PN, Chilongozi DA, Cohen MS, Swanstrom R. HIV-1 populations in blood and breast milk are similar. Virology. 330: 295-303. PMID 15527854 DOI: 10.1016/J.Virol.2004.09.004  0.816
2004 Ritola K, Pilcher CD, Fiscus SA, Hoffman NG, Nelson JA, Kitrinos KM, Hicks CB, Eron JJ, Swanstrom R. Multiple V1/V2 env variants are frequently present during primary infection with human immunodeficiency virus type 1. Journal of Virology. 78: 11208-18. PMID 15452240 DOI: 10.1128/Jvi.78.20.11208-11218.2004  0.753
2004 Swanstrom R, Bosch RJ, Katzenstein D, Cheng H, Jiang H, Hellmann N, Haubrich R, Fiscus SA, Fletcher CV, Acosta EP, Gulick RM. Weighted phenotypic susceptibility scores are predictive of the HIV-1 RNA response in protease inhibitor-experienced HIV-1-infected subjects. The Journal of Infectious Diseases. 190: 886-93. PMID 15295692 DOI: 10.1086/422692  0.525
2004 Brumme ZL, Dong WW, Yip B, Wynhoven B, Hoffman NG, Swanstrom R, Jensen MA, Mullins JI, Hogg RS, Montaner JS, Harrigan PR. Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy. Aids (London, England). 18: F1-9. PMID 15090786 DOI: 10.1097/00002030-200403050-00001  0.762
2004 Rybarczyk BJ, Montefiori D, Johnson PR, West A, Johnston RE, Swanstrom R. Correlation between env V1/V2 region diversification and neutralizing antibodies during primary infection by simian immunodeficiency virus sm in rhesus macaques. Journal of Virology. 78: 3561-71. PMID 15016879 DOI: 10.1128/Jvi.78.7.3561-3571.2004  0.396
2003 Aguirre SR, Ping LH, Barrios Olivera JA, Cardellá VK, Swanstrom R. [Application of SensiScript enzyme to a RT-PCR system for the obtention of RNA of HIV-1 starting serum samples stored at -20 degrees C during a decade]. Revista Cubana De Medicina Tropical. 55: 213-6. PMID 15849930  0.365
2003 Hoffman NG, Schiffer CA, Swanstrom R. Covariation of amino acid positions in HIV-1 protease. Virology. 314: 536-48. PMID 14554082 DOI: 10.1016/S0042-6822(03)00484-7  0.678
2003 Kitrinos KM, Hoffman NG, Nelson JA, Swanstrom R. Turnover of env variable region 1 and 2 genotypes in subjects with late-stage human immunodeficiency virus type 1 infection. Journal of Virology. 77: 6811-22. PMID 12768001 DOI: 10.1128/Jvi.77.12.6811-6822.2003  0.718
2003 Grant RM, Kuritzkes DR, Johnson VA, Mellors JW, Sullivan JL, Swanstrom R, D'Aquila RT, Van Gorder M, Holodniy M, Lloyd Jr RM, Reid C, Morgan GF, Winslow DL. Accuracy of the TRUGENE HIV-1 genotyping kit. Journal of Clinical Microbiology. 41: 1586-93. PMID 12682149 DOI: 10.1128/Jcm.41.4.1586-1593.2003  0.454
2003 Williamson C, Morris L, Maughan MF, Ping LH, Dryga SA, Thomas R, Reap EA, Cilliers T, van Harmelen J, Pascual A, Ramjee G, Gray G, Johnston R, Karim SA, Swanstrom R. Characterization and selection of HIV-1 subtype C isolates for use in vaccine development. Aids Research and Human Retroviruses. 19: 133-44. PMID 12639249 DOI: 10.1089/088922203762688649  0.429
2003 Watkins T, Resch W, Irlbeck D, Swanstrom R. Selection of high-level resistance to human immunodeficiency virus type 1 protease inhibitors. Antimicrobial Agents and Chemotherapy. 47: 759-69. PMID 12543689 DOI: 10.1128/Aac.47.2.759-769.2003  0.679
2002 Pettit SC, Henderson GJ, Schiffer CA, Swanstrom R. Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease. Journal of Virology. 76: 10226-33. PMID 12239298 DOI: 10.1128/Jvi.76.20.10226-10233.2002  0.789
2002 Gulick RM, Hu XJ, Fiscus SA, Fletcher CV, Haubrich R, Cheng H, Acosta E, Lagakos SW, Swanstrom R, Freimuth W, Snyder S, Mills C, Fischl M, Pettinelli C, Katzenstein D. Durability of response to treatment among antiretroviral-experienced subjects: 48-week results from AIDS Clinical Trials Group Protocol 359. The Journal of Infectious Diseases. 186: 626-33. PMID 12195349 DOI: 10.1086/342681  0.443
2002 Resch W, Ziermann R, Parkin N, Gamarnik A, Swanstrom R. Nelfinavir-resistant, amprenavir-hypersusceptible strains of human immunodeficiency virus type 1 carrying an N88S mutation in protease have reduced infectivity, reduced replication capacity, and reduced fitness and process the Gag polyprotein precursor aberrantly. Journal of Virology. 76: 8659-66. PMID 12163585 DOI: 10.1128/Jvi.76.17.8659-8666.2002  0.703
2002 Davis NL, West A, Reap E, MacDonald G, Collier M, Dryga S, Maughan M, Connell M, Walker C, McGrath K, Cecil C, Ping LH, Frelinger J, Olmsted R, Keith P, ... Swanstrom R, et al. Alphavirus replicon particles as candidate HIV vaccines. Iubmb Life. 53: 209-11. PMID 12120997 DOI: 10.1080/15216540212657  0.604
2002 Arroyo MA, Tien H, Pagán M, Swanstrom R, Hillyer GV, Cadilla CL, Meléndez-Guerrero LM. Virologic risk factors for vertical transmission of HIV type 1 in Puerto Rico. Aids Research and Human Retroviruses. 18: 447-60. PMID 11958688 DOI: 10.1089/088922202753614218  0.478
2002 Hoffman NG, Seillier-Moiseiwitsch F, Ahn J, Walker JM, Swanstrom R. Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop. Journal of Virology. 76: 3852-64. PMID 11907225 DOI: 10.1128/Jvi.76.8.3852-3864.2002  0.744
2001 Gorry PR, Bristol G, Zack JA, Ritola K, Swanstrom R, Birch CJ, Bell JE, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky SM, Gabuzda D. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. Journal of Virology. 75: 10073-89. PMID 11581376 DOI: 10.1128/Jvi.75.21.10073-10089.2001  0.539
2001 Resch W, Hoffman N, Swanstrom R. Improved success of phenotype prediction of the human immunodeficiency virus type 1 from envelope variable loop 3 sequence using neural networks. Virology. 288: 51-62. PMID 11543657 DOI: 10.1006/Viro.2001.1087  0.775
2001 Shehu-Xhilaga M, Kraeusslich HG, Pettit S, Swanstrom R, Lee JY, Marshall JA, Crowe SM, Mak J. Proteolytic processing of the p2/nucleocapsid cleavage site is critical for human immunodeficiency virus type 1 RNA dimer maturation. Journal of Virology. 75: 9156-64. PMID 11533179 DOI: 10.1128/JVI.75.19.9156-9164.2001  0.332
2001 McGrath KM, Hoffman NG, Resch W, Nelson JA, Swanstrom R. Using HIV-1 sequence variability to explore virus biology. Virus Research. 76: 137-60. PMID 11410314 DOI: 10.1016/S0168-1702(01)00271-4  0.861
2001 Freel SA, Williams JM, Nelson JA, Patton LL, Fiscus SA, Swanstrom R, Shugars DC. Characterization of human immunodeficiency virus type 1 in saliva and blood plasma by V3-specific heteroduplex tracking assay and genotype analyses. Journal of Virology. 75: 4936-40. PMID 11312368 DOI: 10.1128/Jvi.75.10.4936-4940.2001  0.519
2001 Resch W, Parkin N, Stuelke EL, Watkins T, Swanstrom R. A multiple-site-specific heteroduplex tracking assay as a tool for the study of viral population dynamics. Proceedings of the National Academy of Sciences of the United States of America. 98: 176-81. PMID 11120887 DOI: 10.1073/Pnas.98.1.176  0.713
2001 McGrath KM, Hoffman NG, Resch W, Nelson JA, Swanstrom R. Erratum to “Using HIV-1 sequence variability to explore virus biology” Virus Research. 80: 125. DOI: 10.1016/S0168-1702(01)00349-5  0.85
2000 Wrobel JA, Conrad MJ, Bloedon E, Swanstrom R, Hutchison CA. Analysis of HIV type 1 reverse transcriptase: comparing sequences of viral isolates with mutational data. Aids Research and Human Retroviruses. 16: 2049-54. PMID 11153088 DOI: 10.1089/088922200750054783  0.549
2000 Gulick RM, Hu XJ, Fiscus SA, Fletcher CV, Haubrich R, Cheng H, Acosta E, Lagakos SW, Swanstrom R, Freimuth W, Snyder S, Mills C, Fischl M, Pettinelli C, Katzenstein D. Randomized study of saquinavir with ritonavir or nelfinavir together with delavirdine, adefovir, or both in human immunodeficiency virus-infected adults with virologic failure on indinavir: AIDS Clinical Trials Group study 359 Journal of Infectious Diseases. 182: 1375-1384. PMID 11023461 DOI: 10.1086/315867  0.38
2000 Ping LH, Cohen MS, Hoffman I, Vernazza P, Seillier-Moiseiwitsch F, Chakraborty H, Kazembe P, Zimba D, Maida M, Fiscus SA, Eron JJ, Swanstrom R, Nelson JAE. Effects of genital tract inflammation on human immunodeficiency virus type 1 V3 populations in blood and semen Journal of Virology. 74: 8946-8952. PMID 10982338 DOI: 10.1128/Jvi.74.19.8946-8952.2000  0.443
2000 Nelson JAE, Baribaud F, Edwards T, Swanstrom R. Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection Journal of Virology. 74: 8494-8501. PMID 10954550 DOI: 10.1128/Jvi.74.18.8494-8501.2000  0.453
2000 Swanstrom R, Erona J. Human immunodeficiency virus type-1 protease inhibitorstherapeutic successes and failures, suppression and resistance Pharmacology and Therapeutics. 86: 145-170. PMID 10799712 DOI: 10.1016/S0163-7258(00)00037-1  0.309
2000 Davis NL, Caley IJ, Brown KW, Betts MR, Irlbeck DM, McGrath KM, Connell MJ, Montefiori DC, Frelinger JA, Swanstrom R, Johnson PR, Johnston RE. Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles. Journal of Virology. 74: 371-8. PMID 10590126 DOI: 10.1128/Jvi.74.1.371-378.2000  0.557
2000 Valliancourt M, Shao W, Smith T, Swanstrom R. The nature of resistance to human immunodeficiency virus type-1 protease inhibitors Handbook of Experimental Pharmacology. 140: 33-48. DOI: 10.1007/978-3-642-57092-6_3  0.521
2000 Resch W, Swanstrom R. Protease inhibitor resistance in HIV-1 infection Reviews in Medical Microbiology. 11: 211-221.  0.72
2000 Morris L, Bredell H, Van Harmelen J, Ping LH, Pasqual A, Ramjee G, Abdool Karim S, Gray G, McIntyre J, Maartens G, Swanstrom R, Williamson C. No evidence for naturally occurring mutations resistant to HIV-1 reverse-transcriptase inhibitors among South African HIV-1 subtype C isolates South African Journal of Science. 96: 369-370.  0.442
1999 Caley IJ, Betts MR, Davis NL, Swanstrom R, Frelinger JA, Johnston RE. Venezuelan equine encephalitis virus vectors expressing HIV-1 proteins: vector design strategies for improved vaccine efficacy. Vaccine. 17: 3124-35. PMID 10462249 DOI: 10.1016/S0264-410X(99)00142-5  0.418
1999 Ping LH, Nelson JAE, Hoffman IF, Schock J, Lamers SL, Goodman M, Vernazza P, Kazembe P, Maida M, Zimba D, Goodenow MM, Eron JJ, Fiscus SA, Cohen MS, Swanstrom R. Characterization of V3 sequence heterogeneity in subtype C human immunodeficiency virus type 1 isolates from Malawi: Underrepresentation of X4 variants Journal of Virology. 73: 6271-6281. PMID 10400718 DOI: 10.1128/Jvi.73.8.6271-6281.1999  0.49
1999 Vaillancourt M, Irlbeck D, Smith T, Coombs RW, Swanstrom R. The HIV type 1 protease inhibitor saquinavir can select for multiple mutations that confer increasing resistance Aids Research and Human Retroviruses. 15: 355-363. PMID 10082119 DOI: 10.1089/088922299311321  0.457
1999 Vaillancourt M, Irlbeck D, Smith T, Coombs RW, Swanstrom R. Erratum: The HIV-1 protease inhibitor saquinavir can select for multiple mutations that confer increasing resistance (Aids Research and Human Retroviruses (1999) 15:4 (355-363)) Aids Research and Human Retroviruses. 15. DOI: 10.1089/088922299310674  0.479
1998 Pettit SC, Sanchez R, Smith T, Wehbie R, Derse D, Swanstrom R. HIV type 1 protease inhibitors fail to inhibit HTLV-I Gag processing in infected cells Aids Research and Human Retroviruses. 14: 1007-1014. PMID 9686647 DOI: 10.1089/Aid.1998.14.1007  0.577
1998 Michael NL, Nelson JA, KewalRamani VN, Chang G, O'Brien SJ, Mascola JR, Volsky B, Louder M, White GC, Littman DR, Swanstrom R, O'Brien TR. Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32. Journal of Virology. 72: 6040-7. PMID 9621067 DOI: 10.1128/Jvi.72.7.6040-6047.1998  0.557
1998 Pettit SC, Sheng N, Tritch R, Erickson-Viitanen S, Swanstrom R. The regulation of sequential processing of HIV-1 Gag by the viral protease. Advances in Experimental Medicine and Biology. 436: 15-25. PMID 9561194 DOI: 10.1007/978-1-4615-5373-1_2  0.473
1998 Wrobel JA, Chao SF, Conrad MJ, Merker JD, Swanstrom R, Pielak GJ, Hutchison CA. A genetic approach for identifying critical residues in the fingers and palm subdomains of HIV-1 reverse transcriptase. Proceedings of the National Academy of Sciences of the United States of America. 95: 638-45. PMID 9435245 DOI: 10.1073/Pnas.95.2.638  0.467
1997 Milich L, Margolin BH, Swanstrom R. Patterns of amino acid variability in NSI-like and SI-like V3 sequences and a linked change in the CD4-binding domain of the HIV-1 Env protein. Virology. 239: 108-18. PMID 9426451 DOI: 10.1006/Viro.1997.8821  0.453
1997 Nelson JAE, Fiscus SA, Swanstrom R. Evolutionary variants of the human immunodeficiency virus type 1 V3 region characterized by using a heteroduplex tracking assay Journal of Virology. 71: 8750-8758. PMID 9343234 DOI: 10.1128/Jvi.71.11.8750-8758.1997  0.405
1997 Sheng N, Pettit SC, Tritch RJ, Ozturk DH, Rayner MM, Swanstrom R, Erickson-Viitanen S. Determinants of the human immunodeficiency virus type 1 p15NC-RNA interaction that affect enhanced cleavage by the viral protease. Journal of Virology. 71: 5723-32. PMID 9223458 DOI: 10.1128/Jvi.71.8.5723-5732.1997  0.441
1997 Caley IJ, Betts MR, Irlbeck DM, Davis NL, Swanstrom R, Frelinger JA, Johnston RE. Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector. Journal of Virology. 71: 3031-8. PMID 9060663 DOI: 10.1128/Jvi.71.4.3031-3038.1997  0.398
1996 Kaplan AH, Manchester M, Smith T, Yang YL, Swanstrom R. Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication Journal of Virology. 70: 5840-5844. PMID 8709202 DOI: 10.1128/Jvi.70.9.5840-5844.1996  0.453
1995 Moody MD, Pettit SC, Shao W, Everitt L, Loeb DD, Hutchison CA, Swanstrom R. A side chain at position 48 of the human immunodeficiency virus type-1 protease flap provides an additional specificity determinant. Virology. 207: 475-85. PMID 7886951 DOI: 10.1006/Viro.1995.1107  0.392
1995 Kaplan AH, Manchester M, Everitt L, Swanstrom R. Analysis of human immunodeficiency virus type 1 protease activity in eukaryotic and bacterial cells Methods in Enzymology. 241: 58-69 Publication ye. PMID 7854192 DOI: 10.1016/0076-6879(94)41059-3  0.421
1995 Chao SF, Chan VL, Juranka P, Kaplan AH, Swanstrom R, Hutchison CA. Mutational sensitivity patterns define critical residues in the palm subdomain of the reverse transcriptase of human immunodeficiency virus type 1. Nucleic Acids Research. 23: 803-10. PMID 7535923 DOI: 10.1093/Nar/23.5.803  0.397
1994 Kaplan AH, Michael SF, Wehbie RS, Knigge MF, Paul DA, Everitt L, Kempf DJ, Norbeck DW, Erickson JW, Swanstrom R. Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease Proceedings of the National Academy of Sciences of the United States of America. 91: 5597-5601. PMID 8202533 DOI: 10.1073/Pnas.91.12.5597  0.519
1994 Kaplan AH, Manchester M, Swanstrom R. The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency Journal of Virology. 68: 6782-6786. PMID 8084015 DOI: 10.1128/Jvi.68.10.6782-6786.1994  0.401
1994 Pettit SC, Moody MD, Wehbie RS, Kaplan AH, Nantermet PV, Klein CA, Swanstrom R. The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions Journal of Virology. 68: 8017-8027. PMID 7966591 DOI: 10.1128/Jvi.68.12.8017-8027.1994  0.414
1994 Seillier-Moiseiwitsch F, Margolin BH, Swanstrom R. Genetic variability of the human immunodeficiency virus: statistical and biological issues. Annual Review of Genetics. 28: 559-96. PMID 7893140 DOI: 10.1146/Annurev.Ge.28.120194.003015  0.371
1994 Swanstrom R. Characterization of HIV-1 protease mutants: Random, directed, selected Current Opinion in Biotechnology. 5: 409-413. PMID 7765174 DOI: 10.1016/0958-1669(94)90050-7  0.519
1994 Kaplan AH, Krogstad P, Kempf DJ, Norbeck DW, Swanstrom R. Human immunodeficiency virus type 1 virions composed of unprocessed Gag and Gag-Pol precursors are capable of reverse transcribing viral genomic RNA Antimicrobial Agents and Chemotherapy. 38: 2929-2933. PMID 7695287  0.325
1993 Kaplan AH, Zack JA, Knigge M, Paul DA, Kempf DJ, Norbeck DW, Swanstrom R. Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles Journal of Virology. 67: 4050-4055. PMID 8510215 DOI: 10.1128/Jvi.67.7.4050-4055.1993  0.417
1993 Milich L, Margolin B, Swanstrom R. V3 loop of the human immunodeficiency virus type 1 Env protein: interpreting sequence variability. Journal of Virology. 67: 5623-34. PMID 8350415 DOI: 10.1128/Jvi.67.9.5623-5634.1993  0.41
1993 Anderson S, Shugars DC, Swanstrom R, Garcia JV. Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells Journal of Virology. 67: 4923-4931. PMID 8331733 DOI: 10.1128/Jvi.67.8.4923-4931.1993  0.463
1993 Shugars DC, Smith MS, Glueck DH, Nantermet PV, Seillier-Moiseiwitsch F, Swanstrom R. Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo Journal of Virology. 67: 4639-4650. PMID 8043040 DOI: 10.1128/Jvi.67.8.4639-4650.1993  0.5
1993 Moody M, Pettit SC, Everitt L, Loeb D, Hutchison C, Swanstrom R. Substitution of glycine 48 with glutamic acid alters the substrate specificity of the hiv protease: Second site revertants demonstrate the importance of electrostatic forces Protein Engineering, Design and Selection. 6: 46. DOI: 10.1093/Protein/6.Supplement.46-B  0.434
1993 Pettit SC, Michael SF, Swanstrom R. The specificity of the HIV-1 protease Perspectives in Drug Discovery and Design. 1: 69-83. DOI: 10.1007/Bf02171656  0.56
1992 Dunn MM, Olsen JC, Swanstrom R. Characterization of unintegrated retroviral DNA with long terminal repeat-associated cell-derived inserts. Journal of Virology. 66: 5735-43. PMID 1382140 DOI: 10.1128/Jvi.66.10.5735-5743.1992  0.393
1991 Kaplan AH, Swanstrom R. Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments Proceedings of the National Academy of Sciences of the United States of America. 88: 4528-4532. PMID 2034693  0.308
1991 Bova-Hill C, Olsen JC, Swanstrom R. Genetic analysis of the Rous sarcoma virus subgroup D env gene: mammal tropism correlates with temperature sensitivity of gp85. Journal of Virology. 65: 2073-80. PMID 1848317 DOI: 10.1128/Jvi.65.4.2073-2080.1991  0.4
1991 Manchester M, Loeb DD, Everitt L, Moody M, Hutchison CA, Swanstrom R. Analysis of temperature-sensitive mutants of the HIV-1 protease Advances in Experimental Medicine and Biology. 306: 493-497. PMID 1812748 DOI: 10.1007/978-1-4684-6012-4_63  0.501
1991 Kaplan AH, Swanstrom R. The HIV-1 gag precursor is processed via two pathways: Implications for cytotoxicity Biomedica Biochimica Acta. 50: 647-653. PMID 1801737  0.376
1991 Hutchison CA, Swanstrom R, Loeb DD. Complete mutagenesis of protein coding domains Methods in Enzymology. 202: 356-390. PMID 1784182 DOI: 10.1016/0076-6879(91)02019-6  0.317
1991 Buckheit RW, Swanstrom R. Characterization of an HIV-1 isolate displaying an apparent absence of virion-associated reverse transcriptase activity Aids Research and Human Retroviruses. 7: 295-302. PMID 1712216  0.441
1991 Buckheit R, Hayslette-Doggett C, Swanstrom R. Dextran sulfate and other sulfated polysaccharides induce persistent HIV-1 infection Antiviral Research. 15: 68. DOI: 10.1016/0166-3542(91)90132-B  0.525
1990 Hunter E, Swanstrom R. Retrovirus envelope glycoproteins Current Topics in Microbiology and Immunology. 157: 187-253. PMID 2203609 DOI: 10.1007/978-3-642-75218-6_7  0.352
1990 Olsen JC, Bova-Hill C, Grandgenett DP, Quinn TP, Manfredi JP, Swanstrom R. Rearrangements in unintegrated retroviral DNA are complex and are the result of multiple genetic determinants. Journal of Virology. 64: 5475-84. PMID 2170682 DOI: 10.1128/Jvi.64.11.5475-5484.1990  0.375
1989 Erickson-Viitanen S, Manfredi J, Viitanen P, Tribe DE, Tritch R, Hutchison CA, Loeb DD, Swanstrom R. Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease Aids Research and Human Retroviruses. 5: 577-591. PMID 2692658 DOI: 10.1089/Aid.1989.5.577  0.454
1989 Loeb DD, Swanstrom R, Everitt L, Manchester M, Stamper SE, Hutchison CA. Complete mutagenesis of the HIV-1 protease Nature. 340: 397-400. PMID 2666861 DOI: 10.1038/340397A0  0.339
1989 Loeb DD, Hutchison CA, Edgell MH, Farmerie WG, Swanstrom R. Mutational analysis of human immunodeficiency virus type 1 protease suggests functional homology with aspartic proteinases Journal of Virology. 63: 111-121. PMID 2642305 DOI: 10.1128/Jvi.63.1.111-121.1989  0.398
1988 Bova CA, Olsen JC, Swanstrom R. The avian retrovirus env gene family: molecular analysis of host range and antigenic variants. Journal of Virology. 62: 75-83. PMID 2824857 DOI: 10.1128/Jvi.62.1.75-83.1988  0.413
1987 Farmerie WG, Loeb DD, Casavant NC, Hutchison CA, Edgell MH, Swanstrom R. Expression and processing of the AIDS virus reverse transcriptase in Escherichia coli Science. 236: 305-308. PMID 2436298 DOI: 10.1126/Science.2436298  0.441
1986 Bova CA, Manfredi JP, Swanstrom R. env Genes of avian retroviruses: Nucleotide sequence and molecular recombinants define host range determinants Virology. 152: 343-354. PMID 3014723 DOI: 10.1016/0042-6822(86)90137-6  0.391
1982 Swanstrom R, Varmus HE, Bishop JM. Nucleotide sequence of the 5' noncoding region and part of the gag gene of Rous sarcoma virus. Journal of Virology. 41: 535-41. PMID 6281465 DOI: 10.1128/Jvi.41.2.535-541.1982  0.305
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