| Year |
Citation |
Score |
| 2023 |
Perozzo AM, Brown PMGE, Bowie D. Alternative splicing of the flip/flop cassette and TARP auxiliary subunits engage in a privileged relationship that fine-tunes AMPA receptor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36931708 DOI: 10.1523/JNEUROSCI.2293-22.2023 |
0.745 |
|
| 2021 |
Khanra N, Brown PM, Perozzo AM, Bowie D, Meyerson J. Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife. 10. PMID 33724189 DOI: 10.7554/eLife.66097 |
0.741 |
|
| 2017 |
Brown PMGE, McGuire H, Bowie D. Stargazin and cornichon-3 relieve polyamine block of AMPA receptors by enhancing blocker permeation. The Journal of General Physiology. PMID 29222130 DOI: 10.1085/Jgp.201711895 |
0.723 |
|
| 2017 |
Paramo T, Brown PMGE, Musgaard M, Bowie D, Biggin PC. Functional Validation of Heteromeric Kainate Receptor Models. Biophysical Journal. PMID 28935133 DOI: 10.1016/J.Bpj.2017.08.047 |
0.644 |
|
| 2016 |
Krogsgaard-Larsen N, Delgar CG, Koch K, Brown PM, Møller C, Han L, Huynh TH, Hansen SW, Nielsen B, Bowie D, Pickering DS, Kastrup JS, Frydenvang K, Bunch L. Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. Journal of Medicinal Chemistry. PMID 28005385 DOI: 10.1021/Acs.Jmedchem.6B01516 |
0.615 |
|
| 2016 |
Paramo T, Brown PM, Aurousseau MR, Musgaard M, Bowie D, Biggin PC. Functional and Structural Characterization of the GluK2/GluK5 Heterotetramer Gating Mechanism Biophysical Journal. 110: 289a. DOI: 10.1016/J.Bpj.2015.11.1565 |
0.776 |
|
| 2015 |
Brown PM, Aurousseau MR, Musgaard M, Biggin PC, Bowie D. Kainate receptor pore-forming and auxiliary subunits regulate channel block by a novel mechanism. The Journal of Physiology. PMID 26682513 DOI: 10.1113/Jp271690 |
0.722 |
|
| 2015 |
Accardi MV, Brown PM, Miraucourt LS, Orser BA, Bowie D. α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9676-88. PMID 26134650 DOI: 10.1523/Jneurosci.0513-15.2015 |
0.726 |
|
| 2015 |
Demmer CS, Møller C, Brown PM, Han L, Pickering DS, Nielsen B, Bowie D, Frydenvang K, Kastrup JS, Bunch L. Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1. Acs Chemical Neuroscience. 6: 845-54. PMID 25856736 DOI: 10.1021/Acschemneuro.5B00038 |
0.584 |
|
| 2014 |
Penna A, Wang DS, Yu J, Lecker I, Brown PM, Bowie D, Orser BA. Hydrogen peroxide increases GABAA receptor-mediated tonic current in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10624-34. PMID 25100596 DOI: 10.1523/Jneurosci.0335-14.2014 |
0.637 |
|
| 2014 |
Cox JM, Chu HD, Yang C, Shen HC, Wu Z, Balsells J, Crespo A, Brown P, Zamlynny B, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, et al. Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series. Bioorganic & Medicinal Chemistry Letters. 24: 1681-4. PMID 24630411 DOI: 10.1016/J.Bmcl.2014.02.057 |
0.34 |
|
| 2014 |
Bae J, Ricciardi CJ, Esposito D, Komarnytsky S, Hu P, Curry BJ, Brown PL, Gao Z, Biggerstaff JP, Chen J, Zhao L. Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration. American Journal of Physiology. Cell Physiology. 306: C918-30. PMID 24627558 DOI: 10.1152/Ajpcell.00249.2013 |
0.345 |
|
| 2014 |
Accardi MV, Daniels BA, Brown PM, Fritschy JM, Tyagarajan SK, Bowie D. Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission. Nature Communications. 5: 3168. PMID 24430741 DOI: 10.1038/Ncomms4168 |
0.744 |
|
| 2012 |
Brown P, Aurousseau M, McGuire H, Blunck R, Bowie D. Gating and Stoichiometry of Heteromeric Kainate Receptors Biophysical Journal. 102: 613a. DOI: 10.1016/J.Bpj.2011.11.3342 |
0.791 |
|
| 2011 |
Lachance-Touchette P, Brown P, Meloche C, Kinirons P, Lapointe L, Lacasse H, Lortie A, Carmant L, Bedford F, Bowie D, Cossette P. Novel α1 and γ2 GABAA receptor subunit mutations in families with idiopathic generalized epilepsy. The European Journal of Neuroscience. 34: 237-49. PMID 21714819 DOI: 10.1111/J.1460-9568.2011.07767.X |
0.606 |
|
| 2009 |
Fay AM, Corbeil CR, Brown P, Moitessier N, Bowie D. Functional characterization and in silico docking of full and partial GluK2 kainate receptor agonists. Molecular Pharmacology. 75: 1096-107. PMID 19225180 DOI: 10.1124/Mol.108.054254 |
0.658 |
|
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