Adriana Di Polo - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Johnson TV, Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, Guido W, Kolodkin AL, Mason CA, Ou Y, Reh TA, Ross AG, Samuels BC, Zack DJ. The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration Consortium. Ophthalmology Science. 3: 100390. PMID 38025164 DOI: 10.1016/j.xops.2023.100390  0.382
2023 Shiga Y, Nishida T, Jeoung JW, Di Polo A, Fortune B. Optical Coherence Tomography and Optical Coherence Tomography Angiography: Essential Tools for Detecting Glaucoma and Disease Progression. Frontiers in Ophthalmology. 3. PMID 37982032 DOI: 10.3389/fopht.2023.1217125  0.339
2023 Alarcon-Martinez L, Shiga Y, Villafranca-Baughman D, Cueva Vargas JL, Vidal Paredes IA, Quintero H, Fortune B, Danesh-Meyer H, Di Polo A. Neurovascular dysfunction in glaucoma. Progress in Retinal and Eye Research. 97: 101217. PMID 37778617 DOI: 10.1016/j.preteyeres.2023.101217  0.326
2023 Soucy JR, Aguzzi EA, Cho J, Gilhooley MJ, Keuthan C, Luo Z, Monavarfeshani A, Saleem MA, Wang XW, Wohlschlegel J, Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, et al. Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium. Molecular Neurodegeneration. 18: 64. PMID 37735444 DOI: 10.1186/s13024-023-00655-y  0.453
2023 Tribble JR, Hui F, Quintero H, El Hajji S, Bell K, Di Polo A, Williams PA. Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering. Molecular Aspects of Medicine. 92: 101193. PMID 37331129 DOI: 10.1016/j.mam.2023.101193  0.448
2023 Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Di Polo A, Meyer JS. Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma. Biorxiv : the Preprint Server For Biology. PMID 36711831 DOI: 10.1101/2023.01.04.522687  0.453
2022 Quintero H, Shiga Y, Belforte N, Alarcon-Martinez L, El Hajji S, Villafranca-Baughman D, Dotigny F, Di Polo A. Restoration of mitochondria axonal transport by adaptor Disc1 supplementation prevents neurodegeneration and rescues visual function. Cell Reports. 40: 111324. PMID 36103832 DOI: 10.1016/j.celrep.2022.111324  0.317
2022 Alarcon-Martinez L, Shiga Y, Villafranca-Baughman D, Belforte N, Quintero H, Dotigny F, Cueva Vargas JL, Di Polo A. Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35135877 DOI: 10.1073/pnas.2110329119  0.346
2018 Beckers A, Van Dyck A, Bollaerts I, Van Houcke J, Lefevere E, Andries L, Agostinone J, Van Hove I, Di Polo A, Lemmens K, Moons L. An Antagonistic Axon-Dendrite Interplay Enables Efficient Neuronal Repair in the Adult Zebrafish Central Nervous System. Molecular Neurobiology. PMID 30105671 DOI: 10.1007/s12035-018-1292-5  0.392
2018 Simpson E, Korecki AJ, Fornes O, McGill TJ, Cueva-Vargas JL, Agostinone J, Farkas RA, Hickmott JW, Lam SL, Mathelier A, Renner LM, Stoddard J, Zhou M, Di Polo A, Neuringer M, et al. New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina. Human Gene Therapy. PMID 30062914 DOI: 10.1089/Hum.2018.118  0.376
2018 Agostinone J, Alarcon-Martinez L, Gamlin C, Yu WQ, Wong ROL, Di Polo A. Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury. Brain : a Journal of Neurology. PMID 29931057 DOI: 10.1093/Brain/Awy142  0.401
2017 Ito YA, Di Polo A. Mitochondrial dynamics, transport, and quality control: A bottleneck for retinal ganglion cell viability in optic neuropathies. Mitochondrion. PMID 28866056 DOI: 10.1016/j.mito.2017.08.014  0.389
2017 Chiasseu M, Alarcon-Martinez L, Belforte N, Quintero H, Dotigny F, Destroismaisons L, Vande Velde C, Panayi F, Louis C, Di Polo A. Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease. Molecular Neurodegeneration. 12: 58. PMID 28774322 DOI: 10.1186/s13024-017-0199-3  0.308
2016 Chiasseu M, Cueva Vargas JL, Destroismaisons L, Vande Velde C, Leclerc N, Di Polo A. Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5785-98. PMID 27225768 DOI: 10.1523/Jneurosci.3986-15.2016  0.434
2016 Vargas JL, Belforte N, Di Polo A. The glial cell modulator ibudilast attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma through protein kinase a signaling. Neurobiology of Disease. PMID 27163643 DOI: 10.1016/j.nbd.2016.05.002  0.546
2015 Agostinone J, Di Polo A. Retinal ganglion cell dendrite pathology and synapse loss: Implications for glaucoma. Progress in Brain Research. 220: 199-216. PMID 26497792 DOI: 10.1016/bs.pbr.2015.04.012  0.464
2015 Cueva Vargas JL, Osswald IK, Unsain N, Aurousseau MR, Barker PA, Bowie D, Di Polo A. Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12088-102. PMID 26338321 DOI: 10.1523/Jneurosci.1273-15.2015  0.682
2015 Morquette B, Morquette P, Agostinone J, Feinstein E, McKinney RA, Kolta A, Di Polo A. REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury. Cell Death and Differentiation. 22: 612-25. PMID 25257176 DOI: 10.1038/Cdd.2014.149  0.368
2015 Khazaei MR, Montcalm S, Di Polo A, Fournier AE, Durocher Y, Ong Tone S. Development of a cell permeable competitive antagonist of RhoA and CRMP4 binding, TAT-C4RIP, to promote neurite outgrowth. Journal of Molecular Neuroscience : Mn. 55: 406-15. PMID 25015230 DOI: 10.1007/S12031-014-0350-3  0.495
2014 Wilson AM, Chiodo VA, Boye SL, Brecha NC, Hauswirth WW, Di Polo A. Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is required for neuronal survival after axonal injury. Plos One. 9: e94175. PMID 24714389 DOI: 10.1371/Journal.Pone.0094175  0.628
2013 Slusar JE, Cairns EA, Szczesniak AM, Bradshaw HB, Di Polo A, Kelly ME. The fatty acid amide hydrolase inhibitor, URB597, promotes retinal ganglion cell neuroprotection in a rat model of optic nerve axotomy. Neuropharmacology. 72: 116-25. PMID 23643752 DOI: 10.1016/j.neuropharm.2013.04.018  0.418
2013 Almasieh M, MacIntyre JN, Pouliot M, Casanova C, Vaucher E, Kelly ME, Di Polo A. Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma. Investigative Ophthalmology & Visual Science. 54: 3171-83. PMID 23599333 DOI: 10.1167/Iovs.12-11481  0.732
2013 Wilson AM, Morquette B, Abdouh M, Unsain N, Barker PA, Feinstein E, Bernier G, Di Polo A. ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2205-16. PMID 23365256 DOI: 10.1523/Jneurosci.2635-12.2013  0.604
2012 Almasieh M, Wilson AM, Morquette B, Cueva Vargas JL, Di Polo A. The molecular basis of retinal ganglion cell death in glaucoma. Progress in Retinal and Eye Research. 31: 152-81. PMID 22155051 DOI: 10.1016/J.Preteyeres.2011.11.002  0.757
2012 Wilson AM, Di Polo A. Gene therapy for retinal ganglion cell neuroprotection in glaucoma. Gene Therapy. 19: 127-36. PMID 21975466 DOI: 10.1038/gt.2011.142  0.672
2011 Almasieh M, Lieven CJ, Levin LA, Di Polo A. A cell-permeable phosphine-borane complex delays retinal ganglion cell death after axonal injury through activation of the pro-survival extracellular signal-regulated kinases 1/2 pathway. Journal of Neurochemistry. 118: 1075-86. PMID 21749374 DOI: 10.1111/J.1471-4159.2011.07382.X  0.756
2011 Ahmed Z, Kalinski H, Berry M, Almasieh M, Ashush H, Slager N, Brafman A, Spivak I, Prasad N, Mett I, Shalom E, Alpert E, Di Polo A, Feinstein E, Logan A. Ocular neuroprotection by siRNA targeting caspase-2. Cell Death & Disease. 2: e173. PMID 21677688 DOI: 10.1038/Cddis.2011.54  0.753
2010 Almasieh M, Zhou Y, Kelly ME, Casanova C, Di Polo A. Structural and functional neuroprotection in glaucoma: role of galantamine-mediated activation of muscarinic acetylcholine receptors. Cell Death & Disease. 1: e27. PMID 21364635 DOI: 10.1038/Cddis.2009.23  0.749
2010 Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, Di Polo A, Barker PA. ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3817-22. PMID 20133718 DOI: 10.1073/Pnas.0909276107  0.482
2009 Saragovi HU, Hamel E, Di Polo A. A neurotrophic rationale for the therapy of neurodegenerative disorders. Current Alzheimer Research. 6: 419-23. PMID 19874265 DOI: 10.2174/156720509789207912  0.312
2009 Lebrun-Julien F, Duplan L, Pernet V, Osswald I, Sapieha P, Bourgeois P, Dickson K, Bowie D, Barker PA, Di Polo A. Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5536-45. PMID 19403821 DOI: 10.1523/Jneurosci.0831-09.2009  0.592
2009 Lebrun-Julien F, Morquette B, Douillette A, Saragovi HU, Di Polo A. Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells. Molecular and Cellular Neurosciences. 40: 410-20. PMID 19146958 DOI: 10.1016/J.Mcn.2008.12.005  0.435
2009 Yang C, Lafleur J, Mwaikambo BR, Zhu T, Gagnon C, Chemtob S, Di Polo A, Hardy P. The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration. Investigative Ophthalmology & Visual Science. 50: 1290-8. PMID 18978343 DOI: 10.1167/Iovs.08-1920  0.449
2008 Jarjour AA, Bull SJ, Almasieh M, Rajasekharan S, Baker KA, Mui J, Antel JP, Di Polo A, Kennedy TE. Maintenance of axo-oligodendroglial paranodal junctions requires DCC and netrin-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11003-14. PMID 18945908 DOI: 10.1523/Jneurosci.3285-08.2008  0.703
2008 Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, ... ... Di Polo A, et al. The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis. Nature Medicine. 14: 1067-76. PMID 18836459 DOI: 10.1038/Nm.1873  0.347
2008 Shi Z, Rudzinski M, Meerovitch K, Lebrun-Julien F, Birman E, Di Polo A, Saragovi HU. Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma. The Journal of Biological Chemistry. 283: 29156-65. PMID 18701465 DOI: 10.1074/Jbc.M802365200  0.447
2008 Morquette JB, Di Polo A. Dendritic and synaptic protection: is it enough to save the retinal ganglion cell body and axon? Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 28: 144-54. PMID 18562848 DOI: 10.1097/WNO.0b013e318177edf0  0.479
2008 Lebrun-Julien F, Di Polo A. Molecular and cell-based approaches for neuroprotection in glaucoma. Optometry and Vision Science : Official Publication of the American Academy of Optometry. 85: 417-24. PMID 18521011 DOI: 10.1097/OPX.0b013e31817841f7  0.513
2007 Pernet V, Bourgeois P, Di Polo A. A role for polyamines in retinal ganglion cell excitotoxic death. Journal of Neurochemistry. 103: 1481-90. PMID 17714450 DOI: 10.1111/j.1471-4159.2007.04843.x  0.448
2007 Joly S, Pernet V, Chemtob S, Di Polo A, Lachapelle P. Neuroprotection in the juvenile rat model of light-induced retinopathy: evidence suggesting a role for FGF-2 and CNTF. Investigative Ophthalmology & Visual Science. 48: 2311-20. PMID 17460296 DOI: 10.1167/Iovs.06-1205  0.303
2007 Bertrand J, Di Polo A, McKerracher L. Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists. Neurobiology of Disease. 25: 65-72. PMID 17011202 DOI: 10.1016/J.Nbd.2006.08.008  0.477
2006 Sapieha PS, Hauswirth WW, Di Polo A. Extracellular signal-regulated kinases 1/2 are required for adult retinal ganglion cell axon regeneration induced by fibroblast growth factor-2. Journal of Neuroscience Research. 83: 985-95. PMID 16493686 DOI: 10.1002/Jnr.20803  0.43
2006 Pernet V, Di Polo A. Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo. Brain : a Journal of Neurology. 129: 1014-26. PMID 16418178 DOI: 10.1093/brain/awl015  0.483
2005 Zhou Y, Pernet V, Hauswirth WW, Di Polo A. Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 402-12. PMID 15975850 DOI: 10.1016/J.Ymthe.2005.04.004  0.461
2005 Sapieha PS, Duplan L, Uetani N, Joly S, Tremblay ML, Kennedy TE, Di Polo A. Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS. Molecular and Cellular Neurosciences. 28: 625-35. PMID 15797710 DOI: 10.1016/J.Mcn.2004.10.011  0.445
2005 Pernet V, Hauswirth WW, Di Polo A. Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo. Journal of Neurochemistry. 93: 72-83. PMID 15773907 DOI: 10.1111/J.1471-4159.2005.03002.X  0.445
2003 Sapieha PS, Peltier M, Rendahl KG, Manning WC, Di Polo A. Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury. Molecular and Cellular Neurosciences. 24: 656-72. PMID 14664816 DOI: 10.1016/S1044-7431(03)00228-8  0.418
2002 Cheng L, Sapieha P, Kittlerova P, Hauswirth WW, Di Polo A. TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3977-86. PMID 12019317  0.459
2002 Cheng L, Sapieha P, Kittlerová P, Hauswirth WW, Di Polo A. TrkB Gene Transfer Protects Retinal Ganglion Cells from Axotomy-Induced Death In Vivo The Journal of Neuroscience. 22: 3977-3986. DOI: 10.1523/Jneurosci.22-10-03977.2002  0.458
2000 Di Polo A, Cheng L, Bray GM, Aguayo AJ. Colocalization of TrkB and brain-derived neurotrophic factor proteins in green-red-sensitive cone outer segments. Investigative Ophthalmology & Visual Science. 41: 4014-21. PMID 11053307  0.542
1998 Di Polo A, Aigner LJ, Dunn RJ, Bray GM, Aguayo AJ. Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 3978-83. PMID 9520478 DOI: 10.1073/pnas.95.7.3978  0.569
1997 Di Polo A, Aigner LJ, Dünn RJ, Bray GM, Aguayo AJ. Adenovirus-mediated gene transfer of BDNF delays the death of injured retinal ganglion cells Investigative Ophthalmology and Visual Science. 38: S259.  0.38
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