| Year |
Citation |
Score |
| 2023 |
Curlin JZ, Schmitt K, Remling-Mulder L, Tibbitts CV, O'Connor S, Marx P, Akkina R. Viral evolution of SIV chimpanzee toward HIV-1 using humanized mice. Journal of Medical Primatology. PMID 37658595 DOI: 10.1111/jmp.12675 |
0.558 |
|
| 2023 |
Curlin JZ, Schmitt K, Remling-Mulder L, Tibbitts CV, O'Connor S, Marx P, Akkina R. Characterizing the phenotypic and genetic changes of pre-epidemic HIV-2 group F virus following serial passage in humanized mice. Journal of Medical Primatology. PMID 37658590 DOI: 10.1111/jmp.12674 |
0.487 |
|
| 2023 |
Schmitt K, Curlin JZ, Remling-Mulder L, Aboellail T, Akkina R. Zika virus induced microcephaly and aberrant hematopoietic cell differentiation modeled in novel neonatal humanized mice. Frontiers in Immunology. 14: 1060959. PMID 36825016 DOI: 10.3389/fimmu.2023.1060959 |
0.343 |
|
| 2022 |
Curlin JZ, Schmitt K, Remling-Mulder L, Morrison J, Baczenas JJ, Tibbits CV, Goff K, O'Connor S, Stenglein M, Marx P, Akkina R. Evolution of SIVmac239 following serial passaging in humanized mice. Journal of Medical Primatology. PMID 36030392 DOI: 10.1111/jmp.12614 |
0.341 |
|
| 2022 |
Schmitt K, Curlin J, Remling-Mulder L, Morrison J, Moriarty R, Goff K, Stenglein M, O'Connor S, Marx P, Akkina R. Long-term evolutionary adaptation of SIVcpz toward HIV-1 using a humanized mouse model. Journal of Medical Primatology. PMID 36030391 DOI: 10.1111/jmp.12616 |
0.57 |
|
| 2021 |
Curlin JZ, Schmitt K, Remling-Mulder L, Moriarty R, Baczenas JJ, Goff K, O'Connor S, Stenglein M, Marx PA, Akkina R. In vivo infection dynamics and human adaptive changes of SIVsm-derived viral siblings SIVmac239, SIV and SIVhu in humanized mice as a paralog of HIV-2 genesis. Frontiers in Virology. 1. PMID 37168442 DOI: 10.3389/fviro.2021.813606 |
0.573 |
|
| 2020 |
Schmitt K, Curlin J, Remling-Mulder L, Moriarty R, Goff K, O'Connor S, Stenglein M, Marx P, Akkina R. Mimicking SIV chimpanzee viral evolution toward HIV-1 during cross-species transmission. Journal of Medical Primatology. 49: 284-287. PMID 33460210 DOI: 10.1111/jmp.12485 |
0.527 |
|
| 2020 |
Schmitt K, Curlin J, Remling-Mulder L, Moriarty R, Goff K, O'Connor S, Stenglein M, Marx P, Akkina R. Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice. Frontiers in Microbiology. 11: 1889. PMID 32849468 DOI: 10.3389/Fmicb.2020.01889 |
0.56 |
|
| 2020 |
Curlin J, Schmitt K, Remling-Mulder L, Moriarty R, Goff K, O'Connor S, Stenglein M, Marx P, Akkina R. Evolution of SIVsm in humanized mice towards HIV-2. Journal of Medical Primatology. PMID 32777101 DOI: 10.1111/Jmp.12486 |
0.596 |
|
| 2020 |
Devanathan AS, Fallon JK, White NR, Schauer AP, Van Horne B, Blake K, Sykes C, Kovarova M, Adamson L, Remling-Mulder L, Luciw P, Garcia JV, Akkina R, Pirone JR, Smith PC, et al. Antiretroviral penetration and drug transporter concentrations in the spleens of three preclinical animal models and humans. Antimicrobial Agents and Chemotherapy. PMID 32661005 DOI: 10.1128/Aac.01384-20 |
0.551 |
|
| 2020 |
Schmitt K, Curlin J, Remling-Mulder L, Moriarty R, Goff K, O’Connor S, Stenglein M, Marx P, Akkina R. Cross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice Frontiers in Microbiology. 11. DOI: 10.3389/fmicb.2020.01889 |
0.508 |
|
| 2020 |
Schmitt K, Curlin J, Remling‐Mulder L, Moriarty R, Goff K, O’Connor S, Stenglein M, Marx P, Akkina R. Mimicking SIV chimpanzee viral evolution toward HIV‐1 during cross‐species transmission Journal of Medical Primatology. 49: 284-287. DOI: 10.1111/Jmp.12485 |
0.354 |
|
| 2019 |
Tsuji M, Akkina R. Editorial: Development of Humanized Mouse Models for Infectious Diseases and Cancer. Frontiers in Immunology. 10: 3051. PMID 31998319 DOI: 10.3389/Fimmu.2019.03051 |
0.315 |
|
| 2019 |
Akkina R, Barber DL, Bility MT, Bissig KD, Burwitz BJ, Eichelberg K, Endsley JJ, Garcia JV, Hafner R, Karakousis PC, Korba BE, Koshy R, Lambros C, Menne S, Nuermberger EL, et al. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Current Hiv Research. PMID 31870268 DOI: 10.2174/1570162X18666191223114019 |
0.497 |
|
| 2019 |
Akkina R, Garry R, Bréchot C, Ellerbrok H, Hasegawa H, Menéndez-Arias L, Mercer N, Neyts J, Romanowski V, Segalés J, Vahlne A. 2019 meeting of the global virus network Antiviral Research. 172: 104645. PMID 31697957 DOI: 10.1016/J.Antiviral.2019.104645 |
0.339 |
|
| 2019 |
Devanathan AS, Pirone JR, Akkina R, Remling-Mulder L, Luciw P, Adamson L, Garcia JV, Kovarova M, White NR, Schauer AP, Blake K, Sykes C, Burgunder EM, Srinivas N, Rosen EP, et al. Antiretroviral penetration across three preclinical animal models and humans in eight putative HIV viral reservoirs. Antimicrobial Agents and Chemotherapy. PMID 31611355 DOI: 10.1128/Aac.01639-19 |
0.604 |
|
| 2019 |
Curlin J, Schmitt K, Remling-Mulder L, Moriarty R, Stenglein M, O'Connor S, Marx P, Akkina R. SIVcpz cross-species transmission and viral evolution toward HIV-1 in a humanized mouse model. Journal of Medical Primatology. PMID 31576587 DOI: 10.1111/Jmp.12440 |
0.596 |
|
| 2019 |
Thompson CG, Rosen EP, Prince HMA, White N, Sykes C, de la Cruz G, Mathews M, Deleage C, Estes JD, Charlins P, Mulder LR, Kovarova M, Adamson L, Arora S, Dellon ES, ... ... Akkina R, et al. Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species. Science Translational Medicine. 11. PMID 31270274 DOI: 10.1126/Scitranslmed.Aap8758 |
0.592 |
|
| 2019 |
Burgunder E, Fallon JK, White N, Schauer AP, Sykes C, Remling-Mulder L, Kovarova M, Adamson L, Luciw P, Garcia JV, Akkina R, Smith PC, Kashuba ADM. Antiretroviral drug concentrations in lymph nodes: a cross-species comparison of the effect of drug transporter expression, viral infection, and sex in humanized mice, nonhuman primates, and humans. The Journal of Pharmacology and Experimental Therapeutics. PMID 31235531 DOI: 10.1124/Jpet.119.259150 |
0.499 |
|
| 2019 |
Hu S, Li M, Akkina R. Generation of High-Titer Pseudotyped Lentiviral Vectors. Methods in Molecular Biology (Clifton, N.J.). 1937: 125-134. PMID 30706393 DOI: 10.1007/978-1-4939-9065-8_7 |
0.336 |
|
| 2018 |
Srinivas N, Rosen EP, Gilliland WM, Kovarova M, Remling-Mulder L, De La Cruz G, White N, Adamson L, Schauer AP, Sykes C, Luciw P, Garcia JV, Akkina R, Kashuba AD. Antiretroviral Concentrations and Surrogate Measures of Efficacy in the Brain Tissue and CSF of Preclinical Species. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-35. PMID 30346892 DOI: 10.1080/00498254.2018.1539278 |
0.323 |
|
| 2018 |
Schmitt K, Curlin J, Kumar DM, Remling-Mulder L, Feely S, Stenglein M, O'Connor S, Marx P, Akkina R. SIV progenitor evolution toward HIV: A humanized mouse surrogate model for SIVsm adaptation toward HIV-2. Journal of Medical Primatology. 47: 298-301. PMID 30255956 DOI: 10.1111/Jmp.12380 |
0.651 |
|
| 2018 |
Shrivastava S, Charlins P, Ackley A, Embree H, Dropulic B, Akkina R, Weinberg MS, Morris KV. Stable Transcriptional Repression and Parasitism of HIV-1. Molecular Therapy. Nucleic Acids. 12: 12-18. PMID 30195752 DOI: 10.1016/J.Omtn.2018.04.011 |
0.597 |
|
| 2018 |
Zhou J, Lazar D, Li H, Xia X, Satheesan S, Charlins P, O'Mealy D, Akkina R, Saayman S, Weinberg MS, Rossi JJ, Morris KV. Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1. Theranostics. 8: 1575-1590. PMID 29556342 DOI: 10.7150/Thno.23085 |
0.612 |
|
| 2018 |
Schmitt K, Akkina R. Ultra-Sensitive HIV-1 Latency Viral Outgrowth Assays Using Humanized Mice. Frontiers in Immunology. 9: 344. PMID 29556230 DOI: 10.3389/Fimmu.2018.00344 |
0.674 |
|
| 2018 |
Schmitt K, Charlins P, Veselinovic M, Kinner-Bibeau L, Hu S, Curlin J, Remling-Mulder L, Olson KE, Aboellail T, Akkina R. Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model. Virology. 515: 235-242. PMID 29310105 DOI: 10.1016/J.Virol.2017.12.026 |
0.77 |
|
| 2017 |
Schmitt K, Mohan Kumar D, Curlin J, Remling-Mulder L, Stenglein M, O'Connor S, Marx P, Akkina R. Modeling the evolution of SIV sooty mangabey progenitor virus towards HIV-2 using humanized mice. Virology. 510: 175-184. PMID 28750321 DOI: 10.1016/J.Virol.2017.07.005 |
0.662 |
|
| 2017 |
Charlins P, Schmitt K, Remling-Mulder L, Hogan LE, Hanhauser E, Hobbs KS, Hecht F, Deeks SG, Henrich TJ, Akkina R. A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads. Virology. 507: 135-139. PMID 28432928 DOI: 10.1016/J.Virol.2017.04.011 |
0.605 |
|
| 2017 |
Akkina R, Ellerbrok H, Hall W, Hasagawa H, Kawaguchi Y, Kleanthous H, McSweegan E, Mercer N, Romanowski V, Sawa H, Vahlne A. 2016 International Meeting of the Global Virus Network. Antiviral Research. PMID 28315708 DOI: 10.1016/J.Antiviral.2017.03.005 |
0.386 |
|
| 2016 |
Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and Efficacy of a Lentiviral Vector Containing Three Anti-HIV Genes-CCR5 Ribozyme, Tat-rev siRNA, and TAR Decoy-in SCID-hu Mouse-Derived T Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1182-1188. PMID 28182923 DOI: 10.1038/sj.mt.6300157 |
0.592 |
|
| 2016 |
Hu S, Neff CP, Kumar DM, Habu Y, Akkina SR, Seki T, Akkina R. A humanized mouse model for HIV-2 infection and efficacy testing of a single-pill triple-drug combination anti-retroviral therapy. Virology. 501: 115-118. PMID 27912079 DOI: 10.1016/J.Virol.2016.11.013 |
0.835 |
|
| 2016 |
Veselinovic M, Yang KH, Sykes C, Remling-Mulder L, Kashuba AD, Akkina R. Mucosal tissue pharmacokinetics of the integrase inhibitor raltegravir in a humanized mouse model: Implications for HIV pre-exposure prophylaxis. Virology. 489: 173-178. PMID 26771889 DOI: 10.1016/J.Virol.2015.12.014 |
0.774 |
|
| 2016 |
Veselinovic M, Charlins P, Akkina R. Modeling HIV-1 Mucosal Transmission and Prevention in Humanized Mice. Methods in Molecular Biology (Clifton, N.J.). 1354: 203-20. PMID 26714714 DOI: 10.1007/978-1-4939-3046-3_14 |
0.827 |
|
| 2016 |
Lopez-Lemus UA, Ackley A, Saayman S, Embree H, Dropulic B, Akkina R, Charlins P, Weinberg MS, Morris KV. 532. Stable Transcriptional Repression, Gene Excision, and Parastism of HIV by Conditionally Replicating Lentiviral Vectors Molecular Therapy. 24: S213. DOI: 10.1016/S1525-0016(16)33341-X |
0.606 |
|
| 2015 |
Akkina RK, Allam A, Balazs AB, Blankson J, Burnett JC, Casares S, Garcia JV, Hasenkrug K, Kashanchi F, Kitchen S, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, et al. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary. Aids Research and Human Retroviruses. PMID 26670361 DOI: 10.1089/Aid.2015.0258 |
0.612 |
|
| 2015 |
Hu S, Mohan Kumar D, Sax C, Schuler C, Akkina R. Pseudotyping of lentiviral vector with novel vesiculovirus envelope glycoproteins derived from Chandipura and Piry viruses. Virology. 488: 162-168. PMID 26650691 DOI: 10.1016/J.Virol.2015.11.012 |
0.34 |
|
| 2014 |
Akkina R. Humanized Mice for Studying Human Immune Responses and Generating Human Monoclonal Antibodies. Microbiology Spectrum. 2: 157-171. PMID 26105817 DOI: 10.1128/Microbiolspec.Aid-0003-2012 |
0.473 |
|
| 2014 |
Veselinovic M, Yang KH, LeCureux J, Sykes C, Remling-Mulder L, Kashuba AD, Akkina R. HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model. Virology. 464: 253-63. PMID 25105490 DOI: 10.1016/J.Virol.2014.07.008 |
0.767 |
|
| 2013 |
Bennett MS, Akkina R. Gene therapy strategies for HIV/AIDS: Preclinical modeling in humanized mice Viruses. 5: 3119-3141. PMID 24351796 DOI: 10.3390/V5123119 |
0.648 |
|
| 2013 |
Akkina R. New insights into HIV impact on hematopoiesis. Blood. 122: 2144-2146. PMID 24072846 DOI: 10.1182/Blood-2013-08-518274 |
0.616 |
|
| 2013 |
Taube S, Kolawole AO, Höhne M, Wilkinson JE, Handley SA, Perry JW, Thackray LB, Akkina R, Wobus CE. A mouse model for human norovirus. Mbio. 4. PMID 23860770 DOI: 10.1128/Mbio.00450-13 |
0.476 |
|
| 2013 |
Akkina R. Human immune responses and potential for vaccine assessment in humanized mice. Current Opinion in Immunology. 25: 403-409. PMID 23628166 DOI: 10.1016/J.Coi.2013.03.009 |
0.482 |
|
| 2013 |
Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y. Identification of novel influenza A virus proteins translated from PA mRNA. Journal of Virology. 87: 2455-62. PMID 23236060 DOI: 10.1128/Jvi.02656-12 |
0.312 |
|
| 2013 |
Akkina R. New generation humanized mice for virus research: comparative aspects and future prospects. Virology. 435: 14-28. PMID 23217612 DOI: 10.1016/J.Virol.2012.10.007 |
0.544 |
|
| 2013 |
Palmer BE, Neff CP, LeCureux J, Ehler A, DSouza M, Remling-Mulder L, Korman AJ, Fontenot AP, Akkina R. In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice Journal of Immunology. 190: 211-219. PMID 23209326 DOI: 10.4049/Jimmunol.1201108 |
0.798 |
|
| 2013 |
Zhou J, Neff CP, Swiderski P, Li H, Smith DD, Aboellail T, Remling-Mulder L, Akkina R, Rossi JJ. Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 192-200. PMID 23164935 DOI: 10.1038/Mt.2012.226 |
0.793 |
|
| 2012 |
Veselinovic M, Neff CP, Mulder LR, Akkina R. Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model. Virology. 432: 505-10. PMID 22832125 DOI: 10.1016/J.Virol.2012.06.025 |
0.812 |
|
| 2012 |
Nischang M, Gers-Huber G, Audigé A, Akkina R, Speck RF. Modeling HIV infection and therapies in humanized mice. Swiss Medical Weekly. 142. PMID 22777836 DOI: 10.4414/Smw.2012.13618 |
0.696 |
|
| 2011 |
Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2228-38. PMID 21952167 DOI: 10.1038/Mt.2011.207 |
0.835 |
|
| 2011 |
Akkina R, Berges BK, Palmer BE, Remling L, Neff CP, Kuruvilla J, Connick E, Folkvord J, Gagliardi K, Kassu A, Akkina SR. Humanized Rag1-/-γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes Plos One. 6. PMID 21695116 DOI: 10.1371/Journal.Pone.0020169 |
0.793 |
|
| 2011 |
Neff CP, Kurisu T, Ndolo T, Fox K, Akkina R. A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice Plos One. 6. PMID 21673796 DOI: 10.1371/Journal.Pone.0020209 |
0.825 |
|
| 2011 |
Evans VA, Lal L, Akkina R, Solomon A, Wright E, Lewin SR, Cameron PU. Thymic plasmacytoid dendritic cells are susceptible to productive HIV-1 infection and efficiently transfer R5 HIV-1 to thymocytes in vitro. Retrovirology. 8: 43. PMID 21639903 DOI: 10.1186/1742-4690-8-43 |
0.601 |
|
| 2011 |
Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R. An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice. Science Translational Medicine. 3: 66ra6. PMID 21248316 DOI: 10.1126/Scitranslmed.3001581 |
0.818 |
|
| 2011 |
Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R. 133 Aptamer-siRNA Chimera Therapy Suppresses HIV-1 Viral Loads and Protects from CD4 T-Cell Loss in Humanized (RAG-hu) Mice Journal of Acquired Immune Deficiency Syndromes. 56: 54. DOI: 10.1097/01.Qai.0000397320.40083.Fa |
0.827 |
|
| 2010 |
Neff CP, Ndolo T, Tandon A, Habu Y, Akkina R. Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model. Plos One. 5: e15257. PMID 21203568 DOI: 10.1371/Journal.Pone.0015257 |
0.577 |
|
| 2010 |
Kassu A, Marcus RA, D'Souza MB, Kelly-McKnight EA, Golden-Mason L, Akkina R, Fontenot AP, Wilson CC, Palmer BE. Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 3007-18. PMID 20656923 DOI: 10.4049/Jimmunol.1000156 |
0.563 |
|
| 2010 |
Berges BK, Akkina SR, Remling L, Akkina R. Humanized Rag2(-/-)gammac(-/-) (RAG-hu) mice can sustain long-term chronic HIV-1 infection lasting more than a year. Virology. 397: 100-3. PMID 19922970 DOI: 10.1016/J.Virol.2009.10.034 |
0.637 |
|
| 2009 |
Kassu A, D'Souza M, O'Connor BP, Kelly-McKnight E, Akkina R, Fontenot AP, Palmer BE. Decreased 4-1BB expression on HIV-specific CD4+ T cells is associated with sustained viral replication and reduced IL-2 production. Clinical Immunology (Orlando, Fla.). 132: 234-45. PMID 19406689 DOI: 10.1016/J.Clim.2009.03.531 |
0.53 |
|
| 2009 |
Zhou J, Swiderski P, Li H, Zhang J, Neff CP, Akkina R, Rossi JJ. Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells Nucleic Acids Research. 37: 3094-3109. PMID 19304999 DOI: 10.1093/Nar/Gkp185 |
0.809 |
|
| 2008 |
Tamhane M, Akkina R. Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance. Aids Research and Therapy. 5: 16. PMID 18667075 DOI: 10.1186/1742-6405-5-16 |
0.441 |
|
| 2008 |
Tamhane M, Akkina R. Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance. Aids Research and Therapy. 5: 16. PMID 18667075 DOI: 10.1186/1742-6405-5-16 |
0.441 |
|
| 2008 |
Anderson JS, Akkina R. Human Immunodeficiency Virus Type 1 Restriction by Human–Rhesus Chimeric Tripartite Motif 5α (TRIM 5α) in CD34+ Cell-Derived Macrophages In Vitro and in T Cells In Vivo in Severe Combined Immunodeficient (SCID-hu) Mice Transplanted with Human Fetal Tissue Human Gene Therapy. 19: 217-228. PMID 18279037 DOI: 10.1089/Hum.2007.108 |
0.625 |
|
| 2008 |
Bandi S, Akkina R. Human embryonic stem cell (hES) derived dendritic cells are functionally normal and are susceptible to HIV-1 infection. Aids Research and Therapy. 5: 1. PMID 18215326 DOI: 10.1186/1742-6405-5-1 |
0.572 |
|
| 2008 |
Berges BK, Akkina SR, Folkvord JM, Connick E, Akkina R. Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2-/- gammac -/- (RAG-hu) mice. Virology. 373: 342-51. PMID 18207484 DOI: 10.1016/J.Virol.2007.11.020 |
0.675 |
|
| 2007 |
Kuruvilla JG, Troyer RM, Devi S, Akkina R. Dengue virus infection and immune response in humanized RAG2(-/-)gamma(c)(-/-) (RAG-hu) mice. Virology. 369: 143-52. PMID 17707071 DOI: 10.1016/J.Virol.2007.06.005 |
0.797 |
|
| 2007 |
Anderson JS, Akkina R. Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection Gene Therapy. 14: 1287-1297. PMID 17597795 DOI: 10.1038/Sj.Gt.3302958 |
0.569 |
|
| 2007 |
Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1182-8. PMID 17406343 DOI: 10.1038/Sj.Mt.6300157 |
0.657 |
|
| 2007 |
Konet DS, Anderson JS, Piper J, Akkina R, Suchman E, Carlson J. Short-hairpin RNA expressed from polymerase III promoters mediates RNA interference in mosquito cells. Insect Molecular Biology. 16: 199-206. PMID 17298556 DOI: 10.1111/J.1365-2583.2006.00714.X |
0.305 |
|
| 2006 |
Berges BK, Wheat WH, Palmer BE, Connick E, Akkina R. HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-γc-/- (RAG-hu) mouse model Retrovirology. 3. PMID 17078891 DOI: 10.1186/1742-4690-3-76 |
0.688 |
|
| 2006 |
Yam P, Jensen M, Akkina R, Anderson J, Villacres MC, Wu J, Zaia JA, Yee JK. Ex vivo selection and expansion of cells based on expression of a mutated inosine monophosphate dehydrogenase 2 after HIV vector transduction: effects on lymphocytes, monocytes, and CD34+ stem cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 236-44. PMID 16647299 DOI: 10.1016/J.Ymthe.2006.02.017 |
0.598 |
|
| 2006 |
Anderson JS, Bandi S, Kaufman DS, Akkina R. Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy. Retrovirology. 3: 24. PMID 16623949 DOI: 10.1186/1742-4690-3-24 |
0.441 |
|
| 2006 |
Berges B, Wheat W, Palmer B, Akkina R. HIV-1 infection and CD4 T cell depletion in humanized Rag2-/-yc-/- mice Retrovirology. 3: 1-1. DOI: 10.1186/1742-4690-3-S1-S73 |
0.653 |
|
| 2006 |
Krishnan AY, Zaia JA, Rossi JJ, Molina A, Li M, Lee W, Akkina R, Tsai N, Li S, Yam P, Li H, Yee J, Hsu D, Couture L, DiGiusto D, et al. Autologous Stem Cell Transplantation (ASCT) for AIDS-Related Lymphomas (ARL) and the Potential Role of HIV-Resistant Stem Cells. Blood. 108: 491-491. DOI: 10.1182/Blood.V108.11.491.491 |
0.613 |
|
| 2006 |
Anderson JS, Vermeulen A, Karpilow J, Akkina R. 800. Complete Suppression of CCR5 Expression and Inhibition of HIV-1 Infection by Transfected and Lentiviral Vector Expressed shRNAs Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.889 |
0.526 |
|
| 2006 |
Anderson JS, Akkina R. 757. Engineered Expression of Novel TRIM5 Isoforms Inhibits HIV-1 Infection in CD34 Hematopoietic Stem Cell Derived Macrophages Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.841 |
0.586 |
|
| 2006 |
Tamhane MC, Akkina R. 521. Gene Transfer of an Anti-CCR5 siRNA by Sleeping Beauty (SB) Transposon System Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.592 |
0.505 |
|
| 2006 |
Tamhane MC, Akkina R. 509. Adeno-Associated Vector Mediated Delivery of Anti-HIV Genes Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.579 |
0.57 |
|
| 2006 |
Anderson JS, Bandi S, Kaufman DS, Akkina R. 1046. Derivation of Functionally Normal Macrophages from Human Embryonic Stem (hES) Cells for HIV-1 Gene Therapy Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1142 |
0.471 |
|
| 2005 |
Li MJ, Kim J, Li S, Zaia J, Yee JK, Anderson J, Akkina R, Rossi JJ. Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 900-9. PMID 16115802 DOI: 10.1016/J.Ymthe.2005.07.524 |
0.601 |
|
| 2005 |
Anderson JS, Akkina R. CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection. Retrovirology. 2: 53-53. PMID 16109172 DOI: 10.1186/1742-4690-2-53 |
0.606 |
|
| 2005 |
Anderson JS, Akkina R. TRIM5αrh expression restricts HIV-1 infection in lentiviral vector-transduced CD34+-cell-derived macrophages Molecular Therapy. 12: 687-696. PMID 16081321 DOI: 10.1016/J.Ymthe.2005.07.291 |
0.584 |
|
| 2005 |
Strayer DS, Akkina R, Bunnell BA, Dropulic B, Planelles V, Pomerantz RJ, Rossi JJ, Zaia JA. Current status of gene therapy strategies to treat HIV/AIDS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 823-42. PMID 15922953 DOI: 10.1016/J.Ymthe.2005.01.020 |
0.591 |
|
| 2005 |
Anderson JS, Akkina R. HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector Aids Research and Therapy. 2: 1-12. PMID 15813990 DOI: 10.1186/1742-6405-2-1 |
0.592 |
|
| 2005 |
Anderson J, Akkina R. 439. CXCR4 and CCR5 shRNA Transgenic Macrophages Are Functionally Normal and Resist HIV-1 Infection Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.447 |
0.532 |
|
| 2004 |
Banerjea A, Li M, Remling L, Rossi J, Akkina R. Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages. Aids Research and Therapy. 1: 2-2. PMID 15813986 DOI: 10.1186/1742-6405-1-2 |
0.604 |
|
| 2004 |
Banerjea A, Akkina R. 731. Pseudotyping of Lentiviral Vectors with New Envelope G Proteins from Vesiculoviruses VSV-New Jersey, Chandipura and Piry Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.669 |
0.327 |
|
| 2004 |
Anderson JS, Banerjea A, Li M, Rossi J, Akkina R. 410. Multivalent siRNAs for Combinatorial HIV Gene Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.407 |
0.556 |
|
| 2003 |
Anderson JS, Banerjea A, Akkina R. Bispecific Short Hairpin siRNA Constructs Targeted to CD4, CXCR4, and CCR5 Confer HIV-1 Resistance Oligonucleotides. 13: 303-312. PMID 15000821 DOI: 10.1089/154545703322616989 |
0.578 |
|
| 2003 |
Anderson J, Banerjea A, Planelles V, Akkina R. Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA. Aids Research and Human Retroviruses. 19: 699-706. PMID 13678472 DOI: 10.1089/088922203322280928 |
0.612 |
|
| 2003 |
Akkina R, Banerjea A, Bai J, Anderson J, Li MJ, Rossi J. siRNAs, ribozymes and RNA decoys in modeling stem cell-based gene therapy for HIV/AIDS. Anticancer Research. 23: 1997-2005. PMID 12894572 |
0.533 |
|
| 2003 |
Banerjea A, Li MJ, Bauer G, Remling L, Lee NS, Rossi J, Akkina R. Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages. Molecular Therapy. 8: 62-71. PMID 12842429 DOI: 10.1016/S1525-0016(03)00140-0 |
0.602 |
|
| 2002 |
Bai J, Banda N, Lee NS, Rossi J, Akkina R. RNA-Based Anti-HIV-1 Gene Therapeutic Constructs in SCID-hu Mouse Model Molecular Therapy. 6: 770-782. PMID 12498773 DOI: 10.1006/Mthe.2002.0800 |
0.626 |
|
| 2001 |
Pandya S, Boris-Lawrie K, Leung NJ, Akkina R, Planelles V. Development of an Rev-independent, minimal simian immunodeficiency virus-derived vector system Human Gene Therapy. 12: 847-857. PMID 11339901 DOI: 10.1089/104303401750148847 |
0.566 |
|
| 2001 |
Bai J, Rossi J, Akkina R. Multivalent Anti-CCR5 Ribozymes for Stem Cell-Based HIV Type 1 Gene Therapy Aids Research and Human Retroviruses. 17: 385-399. PMID 11282007 DOI: 10.1089/088922201750102427 |
0.581 |
|
| 2000 |
Bai J, Gorantla S, Banda N, Cagnon L, Rossi J, Akkina R. Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo. Molecular Therapy. 1: 244-254. PMID 10933940 DOI: 10.1006/Mthe.2000.0038 |
0.539 |
|
| 1999 |
Banda NK, Simon GR, Sipple JD, Terrell KL, Archer P, Shpall EJ, Akkina RK, Myers AM, Harrison GS. Depletion of CD34+ CD4+ cells in bone marrow from HIV-1-infected individuals. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 5: 162-72. PMID 10392962 DOI: 10.1053/Bbmt.1999.V5.Pm10392962 |
0.51 |
|
| 1998 |
Banda NK, Akkina RK, Terrell K, Shpall EJ, Tomczak J, Campain J, Claman H, Cagle L, Harrison GS. Diphtheria toxin a gene-mediated HIV-1 protection of cord blood-derived T cells in the SCID-hu mouse model Journal of Hematotherapy and Stem Cell Research. 7: 319-331. PMID 9735863 DOI: 10.1089/Scd.1.1998.7.319 |
0.512 |
|
| 1997 |
Banda NK, Tomczak JA, Shpall EJ, Sipple J, Akkina RK, Steimer KS, Hami L, Curiel TJ, Singer Harrison G. HIV-gp120 induced cell death in hematopoietic progenitor CD34+ cells. Apoptosis : An International Journal On Programmed Cell Death. 2: 61-8. PMID 14646565 DOI: 10.1023/A:1026439726053 |
0.591 |
|
| 1997 |
Banda NK, Tomczak JA, Shpall EJ, Sipple J, Akkina RK, Steimer KS, Hami L, Curiel TJ, Harrison GS. HIV-gp120 induced cell death in hematopoietic progenitor CD34+ cells Apoptosis. 2: 61-68. |
0.513 |
|
| 1996 |
Akkina RK, Walton RM, Chen ML, Li QX, Planelles V, Chen ISY. High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G Journal of Virology. 70: 2581-2585. PMID 8642689 DOI: 10.1128/Jvi.70.4.2581-2585.1996 |
0.532 |
|
| 1994 |
Akkina RK, Rosenblatt JD, Campbell AG, Chen ISY, Zack JA. Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse Blood. 84: 1393-1398. PMID 7520766 DOI: 10.1182/Blood.V84.5.1393.Bloodjournal8451393 |
0.489 |
|
| 1994 |
Akkina R, Rosenblatt J, Campbell A, Chen I, Zack J. Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse Blood. 84: 1393-1398. DOI: 10.1182/blood.V84.5.1393.bloodjournal8451393 |
0.395 |
|
| 1994 |
Akkina R, Rosenblatt J, Campbell A, Chen I, Zack J. Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse Blood. 84: 1393-1398. DOI: 10.1182/blood.v84.5.1393.1393 |
0.395 |
|
| 1991 |
Akkina RK, Richardson JC, Aguilera MC, Chi-Ming Y. Heterogeneous forms of polymerase proteins exist in influenza A virus-infected cells Virus Research. 19: 17-30. PMID 1867008 DOI: 10.1016/0168-1702(91)90091-9 |
0.32 |
|
| 1991 |
Richardson JC, Akkina RK. NS2 protein of influenza virus is found in purified virus and phosphorylated in infected cells Archives of Virology. 116: 69-80. PMID 1825776 DOI: 10.1007/Bf01319232 |
0.341 |
|
| 1990 |
Akkina RK. Antigenic reactivity and electrophoretic migrational heterogeneity of the three polymerase proteins of type A human and animal influenza viruses Archives of Virology. 111: 187-197. PMID 2353872 DOI: 10.1007/Bf01311053 |
0.315 |
|
| 1990 |
Akkina RK, Raisch KP. Intracellular virus-induced polypeptides of pestivirus border disease virus Virus Research. 16: 95-105. PMID 2161595 DOI: 10.1016/0168-1702(90)90046-E |
0.352 |
|
| 1987 |
Akkina RK, Chambers TM, Londo DR, Nayak DP. Intracellular localization of the viral polymerase proteins in cells infected with influenza virus and cells expressing PB1 protein from cloned cDNA Journal of Virology. 61: 2217-2224. PMID 2438429 DOI: 10.1128/Jvi.61.7.2217-2224.1987 |
0.31 |
|
| 1985 |
Akkina RK, Chambers TM, Nayak DP. Mechanism of interference by infective-interfering particles of influenza virus Virus Research. 3: 33. DOI: 10.1016/0168-1702(85)90318-1 |
0.309 |
|
| 1984 |
Akkina RK, Chambers TM, Nayak DP. Expression of defective-interfering influenza virus-specific transcripts and polypeptides in infected cells Journal of Virology. 51: 395-403. PMID 6205168 DOI: 10.1128/Jvi.51.2.395-403.1984 |
0.37 |
|
| 1984 |
Akkina RK, Chambers TM, Nayak DP. Mechanism of interference by defective-interfering particles of influenza virus: Differential reduction of intracellular synthesis of specific polymerase proteins Virus Research. 1: 687-702. DOI: 10.1016/0168-1702(84)90059-5 |
0.344 |
|
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