| Year |
Citation |
Score |
| 2018 |
El Hokayem J, Weeber E, Nawaz Z. Loss of Angelman Syndrome Protein E6AP Disrupts a Novel Antagonistic Estrogen-Retinoic Acid Transcriptional Crosstalk in Neurons. Molecular Neurobiology. PMID 29388081 DOI: 10.1007/S12035-018-0871-9 |
0.546 |
|
| 2017 |
El Hokayem J, Amadei C, Obeid JP, Nawaz Z. Ubiquitination of nuclear receptors. Clinical Science (London, England : 1979). 131: 917-934. PMID 28473472 DOI: 10.1042/Cs20160708 |
0.494 |
|
| 2016 |
El Hokayem J, Brittain GC, Nawaz Z, Bethea JR. Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells. Molecular Neurobiology. PMID 26843107 DOI: 10.1007/S12035-016-9742-4 |
0.47 |
|
| 2014 |
El Hokayem J, Nawaz Z. E6AP in the brain: one protein, dual function, multiple diseases. Molecular Neurobiology. 49: 827-39. PMID 24091829 DOI: 10.1007/S12035-013-8563-Y |
0.469 |
|
| 2014 |
Zhou W, Srinivasan S, Nawaz Z, Slingerland JM. ERα, SKP2 and E2F-1 form a feed forward loop driving late ERα targets and G1 cell cycle progression. Oncogene. 33: 2341-53. PMID 23770852 DOI: 10.1038/Onc.2013.197 |
0.631 |
|
| 2014 |
Zhou W, Sun J, Kaliappan K, Nawaz Z, Slingerland JM. The Roles of E6AP and SCF (Skp1.CUL1.F-box) in SRC stimulated estrogen activated receptor proteolysis and transactivation F1000research. 5. DOI: 10.7490/F1000Research.1095817.1 |
0.371 |
|
| 2013 |
Buffa L, Saeed AM, Nawaz Z. Molecular mechanism of WW-domain binding protein-2 coactivation function in estrogen receptor signaling. Iubmb Life. 65: 76-84. PMID 23233354 DOI: 10.1002/Iub.1105 |
0.557 |
|
| 2012 |
Sun J, Zhou W, Kaliappan K, Nawaz Z, Slingerland JM. ERα phosphorylation at Y537 by Src triggers E6-AP-ERα binding, ERα ubiquitylation, promoter occupancy, and target gene expression. Molecular Endocrinology (Baltimore, Md.). 26: 1567-77. PMID 22865929 DOI: 10.1210/Me.2012-1140 |
0.542 |
|
| 2012 |
McDonald CB, Buffa L, Bar-Mag T, Salah Z, Bhat V, Mikles DC, Deegan BJ, Seldeen KL, Malhotra A, Sudol M, Aqeilan RI, Nawaz Z, Farooq A. Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptors. Journal of Molecular Biology. 422: 58-74. PMID 22634283 DOI: 10.1016/J.Jmb.2012.05.015 |
0.328 |
|
| 2012 |
Andreev VP, Petyuk VA, Brewer HM, Karpievitch YV, Xie F, Clarke J, Camp D, Smith RD, Lieberman AP, Albin RL, Nawaz Z, El Hokayem J, Myers AJ. Label-free quantitative LC-MS proteomics of Alzheimer's disease and normally aged human brains. Journal of Proteome Research. 11: 3053-67. PMID 22559202 DOI: 10.1021/Pr3001546 |
0.309 |
|
| 2012 |
Ramamoorthy S, Tufail R, Hokayem JE, Jorda M, Zhao W, Reis Z, Nawaz Z. Overexpression of ligase defective E6-associated protein, E6-AP, results in mammary tumorigenesis. Breast Cancer Research and Treatment. 132: 97-108. PMID 21553290 DOI: 10.1007/S10549-011-1567-2 |
0.681 |
|
| 2012 |
Tufail R, Jorda M, Zhao W, Reis I, Nawaz Z. Loss of Yes-associated protein (YAP) expression is associated with estrogen and progesterone receptors negativity in invasive breast carcinomas. Breast Cancer Research and Treatment. 131: 743-50. PMID 21399893 DOI: 10.1007/S10549-011-1435-0 |
0.398 |
|
| 2012 |
Buffa L, Nawaz Z. Abstract 947: Molecular mechanism of WBP-2 coactivation function in estrogen receptor transactivation Cancer Research. 72: 947-947. DOI: 10.1158/1538-7445.Am2012-947 |
0.551 |
|
| 2012 |
Sun J, Zhou W, Nawaz Z, Slingerland JM. Cross talk between ERα and Src signaling and its relevance to ER status and hormone responsiveness Advances in Rapid Sex-Steroid Action: New Challenges and New Chances in Breast and Prostate Cancers. 2147483647: 61-78. DOI: 10.1007/978-1-4614-1764-4_4 |
0.347 |
|
| 2011 |
McDonald CB, McIntosh SK, Mikles DC, Bhat V, Deegan BJ, Seldeen KL, Saeed AM, Buffa L, Sudol M, Nawaz Z, Farooq A. Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors. Biochemistry. 50: 9616-27. PMID 21981024 DOI: 10.1021/Bi201286P |
0.366 |
|
| 2011 |
Catoe HW, Nawaz Z. E6-AP facilitates efficient transcription at estrogen responsive promoters through recruitment of chromatin modifiers. Steroids. 76: 897-902. PMID 21530567 DOI: 10.1016/J.Steroids.2011.04.007 |
0.8 |
|
| 2011 |
Abdeen SK, Salah Z, Maly B, Smith Y, Tufail R, Abu-Odeh M, Zanesi N, Croce CM, Nawaz Z, Aqeilan RI. Wwox inactivation enhances mammary tumorigenesis. Oncogene. 30: 3900-6. PMID 21499303 DOI: 10.1038/Onc.2011.115 |
0.359 |
|
| 2011 |
Srinivasan S, Nawaz Z. E3 ubiquitin protein ligase, E6-associated protein (E6-AP) regulates PI3K-Akt signaling and prostate cell growth. Biochimica Et Biophysica Acta. 1809: 119-27. PMID 20826237 DOI: 10.1016/J.Bbagrm.2010.08.011 |
0.627 |
|
| 2010 |
Ramamoorthy S, Dhananjayan SC, Demayo FJ, Nawaz Z. Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development. Molecular Endocrinology (Baltimore, Md.). 24: 2099-113. PMID 20829392 DOI: 10.1210/Me.2010-0116 |
0.748 |
|
| 2010 |
Srinivasan S, Nawaz Z. Molecular biology of estrogen receptor action Hormones, Brain and Behavior Online. 1187-1220. DOI: 10.1016/B978-008088783-8.00035-8 |
0.669 |
|
| 2009 |
Fu W, Ma Q, Chen L, Li P, Zhang M, Ramamoorthy S, Nawaz Z, Shimojima T, Wang H, Yang Y, Shen Z, Zhang Y, Zhang X, Nicosia SV, Zhang Y, et al. MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation. The Journal of Biological Chemistry. 284: 13987-4000. PMID 19321440 DOI: 10.1074/Jbc.M901758200 |
0.666 |
|
| 2008 |
Ramamoorthy S, Nawaz Z. E6-associated protein (E6-AP) is a dual function coactivator of steroid hormone receptors. Nuclear Receptor Signaling. 6: e006. PMID 18432313 DOI: 10.1621/Nrs.06006 |
0.75 |
|
| 2008 |
Ismail A, Catoe H, Dhananjayan S, Nawaz Z. Regulation of nuclear hormone receptor functions by ubiquitin-proteasome pathway Nr Coregulators and Human Diseases. 176-207. DOI: 10.1142/9789812819178_0003 |
0.707 |
|
| 2007 |
Sun J, Nawaz Z, Slingerland JM. Long-range activation of GREB1 by estrogen receptor via three distal consensus estrogen-responsive elements in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 21: 2651-62. PMID 17666587 DOI: 10.1210/Me.2007-0082 |
0.483 |
|
| 2007 |
Chu I, Arnaout A, Loiseau S, Sun J, Seth A, McMahon C, Chun K, Hennessy B, Mills GB, Nawaz Z, Slingerland JM. Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancer. The Journal of Clinical Investigation. 117: 2205-15. PMID 17627304 DOI: 10.1172/Jci21739 |
0.34 |
|
| 2006 |
Dhananjayan SC, Ramamoorthy S, Khan OY, Ismail A, Sun J, Slingerland J, O'Malley BW, Nawaz Z. WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Molecular Endocrinology (Baltimore, Md.). 20: 2343-54. PMID 16772533 DOI: 10.1210/Me.2005-0533 |
0.754 |
|
| 2006 |
Khan OY, Fu G, Ismail A, Srinivasan S, Cao X, Tu Y, Lu S, Nawaz Z. Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland. Molecular Endocrinology (Baltimore, Md.). 20: 544-59. PMID 16254014 DOI: 10.1210/Me.2005-0110 |
0.626 |
|
| 2006 |
Zafar S, Srinivasan S, Nawaz Z. E6-Associated Protein (E6-AP): A Potential Tumor Suppressor Protein for Non-Hodgkin Lymphoma. Blood. 108: 4336-4336. DOI: 10.1182/Blood.V108.11.4336.4336 |
0.599 |
|
| 2005 |
Wu J, Liang Y, Nawaz Z, Hyder SM. Complex agonist-like properties of ICI 182,780 (Faslodex) in human breast cancer cells that predominantly express progesterone receptor-B: implications for treatment resistance. International Journal of Oncology. 27: 1647-59. PMID 16273221 DOI: 10.3892/Ijo.27.6.1647 |
0.427 |
|
| 2005 |
Dhananjayan SC, Ismail A, Nawaz Z. Ubiquitin and control of transcription. Essays in Biochemistry. 41: 69-80. PMID 16250898 DOI: 10.1042/Bse0410069 |
0.753 |
|
| 2005 |
Ismail A, Nawaz Z. Nuclear hormone receptor degradation and gene transcription: an update. Iubmb Life. 57: 483-90. PMID 16081369 DOI: 10.1080/15216540500147163 |
0.544 |
|
| 2005 |
Dennis AP, Lonard DM, Nawaz Z, O'Malley BW. Inhibition of the 26S proteasome blocks progesterone receptor-dependent transcription through failed recruitment of RNA polymerase II. The Journal of Steroid Biochemistry and Molecular Biology. 94: 337-46. PMID 15857753 DOI: 10.1016/J.Jsbmb.2004.11.009 |
0.452 |
|
| 2005 |
Gao X, Mohsin SK, Gatalica Z, Fu G, Sharma P, Nawaz Z. Decreased expression of e6-associated protein in breast and prostate carcinomas. Endocrinology. 146: 1707-12. PMID 15691896 DOI: 10.1210/En.2004-1198 |
0.507 |
|
| 2004 |
Verma S, Ismail A, Gao X, Fu G, Li X, O'Malley BW, Nawaz Z. The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors. Molecular and Cellular Biology. 24: 8716-26. PMID 15367689 DOI: 10.1128/Mcb.24.19.8716-8726.2004 |
0.541 |
|
| 2004 |
Liu Z, Shi HY, Nawaz Z, Zhang M. Tamoxifen induces the expression of maspin through estrogen receptor-alpha. Cancer Letters. 209: 55-65. PMID 15145521 DOI: 10.1016/J.Canlet.2003.11.018 |
0.462 |
|
| 2004 |
Nawaz Z, O'Malley BW. Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription? Molecular Endocrinology (Baltimore, Md.). 18: 493-9. PMID 14673136 DOI: 10.1210/Me.2003-0388 |
0.577 |
|
| 2003 |
Khan OY, Nawaz Z. Nuclear hormone receptor co-regulators. Current Opinion in Drug Discovery & Development. 6: 692-701. PMID 14579519 |
0.401 |
|
| 2003 |
Pearce V, Nawaz Z, Xiao W, Wiedenfeld D, Boyle N, Smith D. 4-ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors. The Journal of Steroid Biochemistry and Molecular Biology. 84: 431-9. PMID 12732288 DOI: 10.1016/S0960-0760(03)00064-5 |
0.493 |
|
| 2003 |
Yan F, Gao X, Lonard DM, Nawaz Z. Specific ubiquitin-conjugating enzymes promote degradation of specific nuclear receptor coactivators. Molecular Endocrinology (Baltimore, Md.). 17: 1315-31. PMID 12663742 DOI: 10.1210/Me.2002-0209 |
0.58 |
|
| 2002 |
Gao X, Loggie BW, Nawaz Z. The roles of sex steroid receptor coregulators in cancer. Molecular Cancer. 1: 7. PMID 12473178 DOI: 10.1186/1476-4598-1-7 |
0.491 |
|
| 2002 |
Gao X, Nawaz Z. Progesterone receptors - animal models and cell signaling in breast cancer: Role of steroid receptor coactivators and corepressors of progesterone receptors in breast cancer. Breast Cancer Research : Bcr. 4: 182-6. PMID 12223121 DOI: 10.1186/Bcr449 |
0.492 |
|
| 2002 |
Smith CL, DeVera DG, Lamb DJ, Nawaz Z, Jiang YH, Beaudet AL, O'Malley BW. Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. Molecular and Cellular Biology. 22: 525-35. PMID 11756548 DOI: 10.1128/Mcb.22.2.525-535.2002 |
0.501 |
|
| 2001 |
Dennis AP, Haq RU, Nawaz Z. Importance of the regulation of nuclear receptor degradation Frontiers in Bioscience : a Journal and Virtual Library. 6. PMID 11487464 DOI: 10.2741/Dennis |
0.555 |
|
| 2001 |
Zhao HH, Herrera RE, Coronado-Heinsohn E, Yang MC, Ludes-Meyers JH, Seybold-Tilson KJ, Nawaz Z, Yee D, Barr FG, Diab SG, Brown PH, Fuqua SAW, Osborne CK. Forkhead Homologue in Rhabdomyosarcoma Functions as a Bifunctional Nuclear Receptor-interacting Protein with Both Coactivator and Corepressor Functions Journal of Biological Chemistry. 276: 27907-27912. PMID 11353774 DOI: 10.1074/Jbc.M104278200 |
0.508 |
|
| 2000 |
Sivaraman L, Nawaz Z, Medina D, Conneely OM, O'Malley BW. The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis Breast Cancer Research and Treatment. 62: 185-195. PMID 11072783 DOI: 10.1023/A:1006410111706 |
0.554 |
|
| 2000 |
Hyder SM, Huang JC, Nawaz Z, Boettger-Tong H, Mäkelä S, Chiappetta C, Stancel GM. Regulation of vascular endothelial growth factor expression by estrogens and progestins Environmental Health Perspectives. 108: 785-790. PMID 11035983 DOI: 10.2307/3454307 |
0.405 |
|
| 2000 |
Li J, Wang J, Nawaz Z, Liu JM, Qin J, Wong J. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3 Embo Journal. 19: 4342-4350. PMID 10944117 DOI: 10.1093/Emboj/19.16.4342 |
0.38 |
|
| 2000 |
Lonard DM, Nawaz Z, Smith CL, O'Malley BW. The 26S proteasome is required for estrogen receptor-α and coactivator turnover and for efficient estrogen receptor-α transactivation Molecular Cell. 5: 939-948. PMID 10911988 DOI: 10.1016/S1097-2765(00)80259-2 |
0.501 |
|
| 2000 |
Hyder SM, Nawaz Z, Chiappetta C, Stancel GM. Identification of functional estrogen response elements in the gene coding for the potent angiogenic factor vascular endothelial growth factor Cancer Research. 60: 3183-3190. PMID 10866309 |
0.332 |
|
| 1999 |
Robinson CE, Wu X, Nawaz Z, Ona Te SA, Gimble JM. A Corepressor and Chicken Ovalbumin Upstream Promoter Transcriptional Factor Proteins Modulate Peroxisome Proliferator-Activated Receptor-γ2/Retinoid X Receptor α-Activated Transcription from the Murine Lipoprotein Lipase Promoter. Endocrinology. 140: 1586-1593. PMID 28200887 DOI: 10.1210/endo.140.4.6653 |
0.353 |
|
| 1999 |
McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: Multiple enzymes, multiple complexes, multiple functions Journal of Steroid Biochemistry and Molecular Biology. 69: 3-12. PMID 10418975 DOI: 10.1016/S0960-0760(98)00144-7 |
0.554 |
|
| 1999 |
Robinson CE, Wu X, Nawaz Z, Onãte SA, Gimble JM. A corepressor and chicken ovalbumin upstream promoter transcriptional factor proteins modulate peroxisome proliferator-activated receptor- γ2/retinoid X receptor α-activated transcription from the murine lipoprotein lipase promoter Endocrinology. 140: 1586-1593. PMID 10098492 DOI: 10.1210/Endo.140.4.6653 |
0.51 |
|
| 1999 |
Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BW. Proteasome-dependent degradation of the human estrogen receptor Proceedings of the National Academy of Sciences of the United States of America. 96: 1858-1862. PMID 10051559 DOI: 10.1073/Pnas.96.5.1858 |
0.549 |
|
| 1999 |
Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily Molecular and Cellular Biology. 19: 1182-1189. PMID 9891052 DOI: 10.1128/Mcb.19.2.1182 |
0.573 |
|
| 1998 |
Mckenna NJ, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Distinct steady-state nuclear receptor coregulator complexes exist in vivo Proceedings of the National Academy of Sciences of the United States of America. 95: 11697-11702. PMID 9751728 DOI: 10.1073/Pnas.95.20.11697 |
0.544 |
|
| 1997 |
Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT) Molecular Endocrinology. 11: 714-724. PMID 9171235 DOI: 10.1210/Mend.11.6.0002 |
0.462 |
|
| 1997 |
Smith CL, Nawaz Z, O'Malley BW. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen Molecular Endocrinology. 11: 657-666. PMID 9171229 DOI: 10.1210/Mend.11.6.0009 |
0.4 |
|
| 1996 |
Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor Proceedings of the National Academy of Sciences of the United States of America. 93: 12195-12199. PMID 8901556 DOI: 10.1073/Pnas.93.22.12195 |
0.426 |
|
| 1995 |
Nawaz Z, Tsai MJ, O'Malley BW. Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor β Proceedings of the National Academy of Sciences of the United States of America. 92: 11691-11695. PMID 8524830 DOI: 10.1073/Pnas.92.25.11691 |
0.456 |
|
| 1995 |
Baniahmad C, Nawaz Z, Baniahmad A, Gleeson MAG, Tsai MJ, O'Malley BW. Enhancement of human estrogen receptor activity by SPT6: A potential coactivator Molecular Endocrinology. 9: 34-43. PMID 7760849 DOI: 10.1210/Mend.9.1.7760849 |
0.533 |
|
| 1995 |
Hyder SM, Nawaz Z, Chiappetta C, Yokoyama K, Stancel GM. The protooncogene c-jun contains an unusual estrogen-inducible enhancer within the coding sequence Journal of Biological Chemistry. 270: 8506-8513. PMID 7721748 DOI: 10.1074/Jbc.270.15.8506 |
0.329 |
|
| 1995 |
Burris TP, Nawaz Z, Tsai MJ, O'Malley BW. A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors Proceedings of the National Academy of Sciences of the United States of America. 92: 9525-9529. PMID 7568167 DOI: 10.1073/Pnas.92.21.9525 |
0.488 |
|
| 1994 |
Nawaz Z, Baniahmad C, Burris TP, O'Malley BW, Stillman DJ, TsaiTsaiTsai MJ. The yeast SIN3 gene product negatively regulates the activity of the human progesterone receptor and positively regulates the activities of GAL4 and the HAP1 activator Mgg Molecular &Amp; General Genetics. 245: 724-733. PMID 7830720 DOI: 10.1007/Bf00297279 |
0.497 |
|
| 1993 |
Nawaz Z, Stancel GM, McDonnell DP, Hyder SM. Creation of an active estrogen-responsive element by a single base change in the flanking sequence of a cellular oncogene: A possible mechanism for hormonal carcinogenesis? Molecular Carcinogenesis. 7: 76-82. PMID 8457291 DOI: 10.1002/Mc.2940070204 |
0.443 |
|
| 1993 |
Fuqua SA, Allred DC, Elledge RM, Krieg SL, Benedix MG, Nawaz Z, O'Malley BW, Greene GL, McGuire WL. The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain. Breast Cancer Research and Treatment. 26: 191-202. PMID 8219256 DOI: 10.1007/Bf00689692 |
0.408 |
|
| 1991 |
Pham TA, Elliston JF, Nawaz Z, Mcdonnell DP, Tsai MJ, O'Malley BW. Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers Proceedings of the National Academy of Sciences of the United States of America. 88: 3125-3129. PMID 2014231 DOI: 10.1073/Pnas.88.8.3125 |
0.479 |
|
| 1991 |
McDonnell DP, Nawaz Z, Densmore C, Weigel NL, Pham TA, Clark JH, O'Malley BW. High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae Journal of Steroid Biochemistry and Molecular Biology. 39: 291-297. PMID 1911419 DOI: 10.1016/0960-0760(91)90038-7 |
0.441 |
|
| 1991 |
McDonnell DP, Nawaz Z, O'Malley BW. In situ distinction between steroid receptor binding and transactivation at a target gene Molecular and Cellular Biology. 11: 4350-4355. PMID 1875926 DOI: 10.1128/Mcb.11.9.4350 |
0.442 |
|
| 1990 |
Wittliff JL, Wenz LL, Dong J, Nawaz Z, Butt TR. Expression and characterization of an active human estrogen receptor as a ubiquitin fusion protein from Escherichia coli. The Journal of Biological Chemistry. 265: 22016-22. PMID 2174894 |
0.388 |
|
| Show low-probability matches. |