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Margaret A. Young, Ph.D. - Publications

Affiliations: 
2013 Biology & Biomedical Sciences (Immunology) Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Genetics, Molecular Biology, Oncology
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Spencer DH, Young MA, Lamprecht TL, Helton NM, Fulton R, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Miller CA, Klco JM, Wilson RK, Ley TJ. Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells. Leukemia. 29: 1279-89. PMID 25600023 DOI: 10.1038/Leu.2015.6  0.514
2014 Russler-Germain DA, Spencer DH, Young MA, Lamprecht TL, Miller CA, Fulton R, Meyer MR, Erdmann-Gilmore P, Townsend RR, Wilson RK, Ley TJ. The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers. Cancer Cell. 25: 442-54. PMID 24656771 DOI: 10.1016/J.Ccr.2014.02.010  0.593
2013 Russler-Germain DA, Spencer DH, Young MA, Lamprecht T, Miller C, Fulton RS, Gilmore P, Townsend R, Ley TJ. R882H DNMT3A Causes Dominant-Negative Inhibition Of WT DNMT3A Blood. 122: 3812-3812. DOI: 10.1182/Blood.V122.21.3812.3812  0.585
2013 Spencer DH, Young MA, Klco JM, Ley TJ. Comprehensive Analysis Of HOX Gene Expression and DNA Methylation From 189 Primary AMLs Demonstrates Canonical Patterns Associated With Hematopoietic Stem/Progenitors and Recurrent AML Mutations Blood. 122: 2496-2496. DOI: 10.1182/Blood.V122.21.2496.2496  0.566
2012 Young MA, Larson DE, Sun CW, George DR, Ding L, Miller CA, Lin L, Pawlik KM, Chen K, Fan X, Schmidt H, Kalicki-Veizer J, Cook LL, Swift GW, Demeter RT, et al. Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells. Cell Stem Cell. 10: 570-82. PMID 22542160 DOI: 10.1016/J.Stem.2012.03.002  0.506
2012 Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 481: 506-10. PMID 22237025 DOI: 10.1038/Nature10738  0.586
2012 Germain DA, Lamprecht T, Young M, Ley TJ. The De Novo DNA Methylation Activity of WT DNMT3A Is Inhibited by R882H DNMT3A and DNMT3B3 in Vitro Blood. 120: 1329-1329. DOI: 10.1182/Blood.V120.21.1329.1329  0.561
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