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Angelika Doetzlhofer - Publications

Affiliations: 
Neuroscience Johns Hopkins University, Baltimore, MD 
Area:
Inner Ear Development
Website:
http://neuroscience.jhu.edu/AngelikaDoetzlhofer.php
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Li XJ, Morgan C, Nadar-Ponniah PT, Kolanus W, Doetzlhofer A. TRIM71 reactivation enhances the mitotic and hair cell-forming potential of cochlear supporting cells. Embo Reports. e56562. PMID 37492931 DOI: 10.15252/embr.202256562  0.535
2023 Li XJ, Morgan C, Nadar-Ponniah PT, Kolanus W, Doetzlhofer A. Reactivation of the progenitor gene Trim71 enhances the mitotic and hair cell-forming potential of cochlear supporting cells. Biorxiv : the Preprint Server For Biology. PMID 36711735 DOI: 10.1101/2023.01.12.523802  0.531
2022 Koo HY, Kim MA, Min H, Hwang JY, Prajapati-DiNubila M, Kim KS, Matzuk MM, Park JW, Doetzlhofer A, Kim UK, Bok J. Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals. Proceedings of the National Academy of Sciences of the United States of America. 120: e2213099120. PMID 36577057 DOI: 10.1073/pnas.2213099120  0.331
2022 Li XJ, Morgan C, Goff LA, Doetzlhofer A. Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea. Science Advances. 8: eabj7651. PMID 35148175 DOI: 10.1126/sciadv.abj7651  0.471
2020 Chrysostomou E, Zhou L, Darcy YL, Graves KA, Doetzlhofer A, Cox BC. The Notch Ligand Jagged1 is Required for the Formation, Maintenance, and Survival of Hensen's Cells in the Mouse Cochlea. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33127852 DOI: 10.1523/JNEUROSCI.1192-20.2020  0.504
2020 Li XJ, Doetzlhofer A. LIN28B/ control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling. Proceedings of the National Academy of Sciences of the United States of America. 117: 22225-22236. PMID 32826333 DOI: 10.1073/Pnas.2000417117  0.64
2020 Evsen L, Li X, Zhang S, Razin S, Doetzlhofer A. miRNAs inhibit CHD7 expression and control auditory-sensory progenitor cell behavior in the developing inner ear. Development (Cambridge, England). 147. PMID 32816902 DOI: 10.1242/Dev.183384  0.704
2019 Prajapati-DiNubila M, Benito-Gonzalez A, Golden EJ, Zhang S, Doetzlhofer A. A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea. Elife. 8. PMID 31187730 DOI: 10.7554/Elife.47613  0.619
2019 Prajapati-DiNubila M, Benito-Gonzalez A, Golden EJ, Zhang S, Doetzlhofer A. Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea Elife. DOI: 10.7554/Elife.47613.015  0.503
2016 Basch ML, Brown RM, Jen HI, Semerci F, Depreux F, Edlund R, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK. Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 5. PMID 27966429 DOI: 10.7554/Elife.19921  0.779
2016 Doetzlhofer A, Avraham KB. Insights into inner ear-specific gene regulation: epigenetics and non-coding RNAs in inner ear development and regeneration. Seminars in Cell & Developmental Biology. PMID 27836639 DOI: 10.1016/J.Semcdb.2016.11.002  0.482
2016 Evsen L, Doetzlhofer A. Gene Transfer into the Chicken Auditory Organ by In Ovo Micro-electroporation. Journal of Visualized Experiments : Jove. PMID 27167684 DOI: 10.3791/53864  0.712
2016 Campbell DP, Chrysostomou E, Doetzlhofer A. Canonical Notch signaling plays an instructive role in auditory supporting cell development. Scientific Reports. 6: 19484. PMID 26786414 DOI: 10.1038/Srep19484  0.581
2016 Basch ML, Brown RM, Jen H, Semerci F, Depreux F, Edlund RK, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK. Author response: Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates Elife. DOI: 10.7554/Elife.19921.015  0.754
2015 Golden EJ, Benito-Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proceedings of the National Academy of Sciences of the United States of America. 112: E3864-73. PMID 26139524 DOI: 10.1073/Pnas.1501077112  0.581
2014 Benito-Gonzalez A, Doetzlhofer A. Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12865-76. PMID 25232121 DOI: 10.1523/Jneurosci.1494-14.2014  0.595
2013 Korrapati S, Roux I, Glowatzki E, Doetzlhofer A. Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea. Plos One. 8: e73276. PMID 24023676 DOI: 10.1371/Journal.Pone.0073276  0.643
2009 Doetzlhofer A, Basch ML, Ohyama T, Gessler M, Groves AK, Segil N. Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Developmental Cell. 16: 58-69. PMID 19154718 DOI: 10.1016/J.Devcel.2008.11.008  0.799
2007 Laine H, Doetzlhofer A, Mantela J, Ylikoski J, Laiho M, Roussel MF, Segil N, Pirvola U. p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1434-44. PMID 17287518 DOI: 10.1523/Jneurosci.4956-06.2007  0.544
2006 White PM, Doetzlhofer A, Lee YS, Groves AK, Segil N. Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature. 441: 984-7. PMID 16791196 DOI: 10.1038/Nature04849  0.781
2006 Doetzlhofer A, White P, Lee YS, Groves A, Segil N. Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea. Brain Research. 1091: 282-8. PMID 16616734 DOI: 10.1016/J.Brainres.2006.02.071  0.783
2004 Doetzlhofer A, White PM, Johnson JE, Segil N, Groves AK. In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme. Developmental Biology. 272: 432-47. PMID 15282159 DOI: 10.1016/J.Ydbio.2004.05.013  0.791
2003 Lumpkin EA, Collisson T, Parab P, Omer-Abdalla A, Haeberle H, Chen P, Doetzlhofer A, White P, Groves A, Segil N, Johnson JE. Math1-driven GFP expression in the developing nervous system of transgenic mice. Gene Expression Patterns : Gep. 3: 389-95. PMID 12915300 DOI: 10.1016/S1567-133X(03)00089-9  0.739
2003 Schuettengruber B, Doetzlhofer A, Kroboth K, Wintersberger E, Seiser C. Alternate activation of two divergently transcribed mouse genes from a bidirectional promoter is linked to changes in histone modification. The Journal of Biological Chemistry. 278: 1784-93. PMID 12411446 DOI: 10.1074/Jbc.M204843200  0.323
1998 Sutterluety H, Bartl S, Doetzlhofer A, Khier H, Wintersberger E, Seiser C. Growth-regulated antisense transcription of the mouse thymidine kinase gene. Nucleic Acids Research. 26: 4989-95. PMID 9776764 DOI: 10.1093/Nar/26.21.4989  0.373
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