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Peter J. Roach - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Microbiology Biology
Website:
https://medicine.iu.edu/faculty/15102/roach-peter/

191 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ullman JC, Mellem KT, Xi Y, Ramanan V, Merritt H, Choy R, Gujral T, Young LEA, Blake K, Tep S, Homburger JR, O'Regan A, Ganesh S, Wong P, Satterfield TF, ... ... Roach PJ, et al. Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Science Translational Medicine. 16: eadf1691. PMID 38232139 DOI: 10.1126/scitranslmed.adf1691  0.724
2022 Fastman NM, Liu Y, Ramanan V, Merritt H, Ambing E, DePaoli-Roach AA, Roach PJ, Hurley TD, Mellem KT, Ullman JC, Green E, Morgans D, Tzitzilonis C. The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex. Cell Reports. 40: 111041. PMID 35793618 DOI: 10.1016/j.celrep.2022.111041  0.723
2021 Sun RC, Young LEA, Bruntz RC, Markussen KH, Zhou Z, Conroy LR, Hawkinson TR, Clarke HA, Stanback AE, Macedo JKA, Emanuelle S, Brewer MK, Rondon AL, Mestas A, Sanders WC, ... ... Roach PJ, et al. Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Cell Metabolism. PMID 34043942 DOI: 10.1016/j.cmet.2021.05.003  0.7
2020 Chown EE, Wang P, Zhao X, Crowder JJ, Strober JW, Sullivan MA, Xue Y, Bennett CS, Perri AM, Evers BM, Roach PJ, Depaoli-Roach AA, Akman HO, Pederson BA, Minassian BA. GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease. Annals of Clinical and Translational Neurology. PMID 33034425 DOI: 10.1002/acn3.51211  0.537
2020 Tang B, Frasinyuk MS, Chikwana VM, Mahalingan KK, Morgan CA, Segvich DM, Bondarenko SP, Mrug GP, Wyrebek P, Watt DS, DePaoli-Roach AA, Roach PJ, Hurley TD. Discovery and development of small-molecule inhibitors of glycogen synthase. Journal of Medicinal Chemistry. PMID 32134266 DOI: 10.1021/acs.jmedchem.9b01851  0.721
2020 Young LEA, Brizzee CO, Macedo JKA, Murphy RD, Contreras CJ, DePaoli-Roach AA, Roach PJ, Gentry MS, Sun RC. Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry. Carbohydrate Polymers. 230: 115651. PMID 31887930 DOI: 10.1016/J.Carbpol.2019.115651  0.607
2020 Visuttijai K, Hedberg-Oldfors C, Thomsen C, Glamuzina E, Kornblum C, Tasca G, Hernandez-Lain A, Sandstedt J, Dellgren G, Roach P, Oldfors A. Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage. The Journal of Clinical Endocrinology and Metabolism. 105: 557-566. PMID 31628455 DOI: 10.1210/Clinem/Dgz075  0.328
2019 Brewer MK, Uittenbogaard A, Austin GL, Segvich DM, DePaoli-Roach A, Roach PJ, McCarthy JJ, Simmons ZR, Brandon JA, Zhou Z, Zeller J, Young LEA, Sun RC, Pauly JR, Aziz NM, et al. Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion. Cell Metabolism. PMID 31353261 DOI: 10.1016/J.Cmet.2019.07.002  0.56
2019 Burlet-Godinot S, Petit J-, Roach PJ, Depaoli-Roach AA, Magistretti PJ. New insights into the “Glycogenetic” hypothesis of sleep: brain glycogen availability affects REM-related theta rhythm providing a possible link with emotional memory mechanisms Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.841  0.526
2018 Gentry MS, Guinovart JJ, Minassian BA, Roach PJ, Serratosa J. Lafora disease offers a unique window into neuronal glycogen metabolism. The Journal of Biological Chemistry. PMID 29483193 DOI: 10.1074/Jbc.R117.803064  0.371
2018 Lawrence MM, Huot JR, Peck B, Wen Y, Shields M, Madhiwala R, Skurat A, Roach PJ, Kane E, Reitzel A, Miller BF, Hamilton KL, Arthur ST, Gordon SE. Glycogen Enhancement Augments Overload-Induced Protein Synthesis, Growth, and Myogenesis in Aged Skeletal Muscle. Medicine & Science in Sports & Exercise. 50: 487-488. DOI: 10.1249/01.Mss.0000536686.61346.C7  0.319
2017 Irimia JM, Meyer CM, Segvich DM, Surendran S, DePaoli-Roach AA, Morral N, Roach PJ. Lack of liver glycogen causes hepatic insulin resistance and Steatosis in mice. The Journal of Biological Chemistry. PMID 28483921 DOI: 10.1074/Jbc.M117.786525  0.631
2017 Skurat AV, Segvich D, DePaoli-Roach AA, Roach PJ. NOVEL METHOD FOR DETECTION OF GLYCOGEN IN CELLS. Glycobiology. PMID 28077463 DOI: 10.1093/Glycob/Cwx005  0.659
2017 Burlet-Godinot S, Allaman I, Grenningloh G, Roach P, Depaoli-Roach A, Magistretti P, Petit J. Functional consequences of brain glycogen deficiency on the sleep-wake cycle regulation in PTG-KO mice Sleep Medicine. 40: e43-e44. DOI: 10.1016/J.Sleep.2017.11.121  0.544
2016 Ruchti E, Roach PJ, DePaoli-Roach AA, Magistretti PJ, Allaman I. Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes Ibro Reports. 1: 46-53. PMID 30135927 DOI: 10.1016/J.Ibror.2016.10.002  0.623
2016 Mahalingan KK, Baskaran S, Depaoli-Roach AA, Roach PJ, Hurley TD. Redox switch for the inhibited state of yeast glycogen synthase mimics regulation by phosphorylation. Biochemistry. PMID 27935293 DOI: 10.1021/Acs.Biochem.6B00884  0.792
2016 Scheffler TL, Park S, Roach PJ, Gerrard DE. Gain of function AMP-activated protein kinase γ3 mutation (AMPKγ3R200Q) in pig muscle increases glycogen storage regardless of AMPK activation. Physiological Reports. 4. PMID 27302990 DOI: 10.14814/Phy2.12802  0.445
2016 Contreras CJ, Segvich DM, Mahalingan K, Chikwana VM, Kirley TL, Hurley TD, DePaoli-Roach AA, Roach PJ. Incorporation of phosphate into glycogen by glycogen synthase. Archives of Biochemistry and Biophysics. PMID 27036853 DOI: 10.1016/J.Abb.2016.03.020  0.754
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Roach PJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.443
2015 Roach PJ. Glycogen phosphorylation and Lafora disease. Molecular Aspects of Medicine. PMID 26278984 DOI: 10.1016/J.Mam.2015.08.003  0.431
2015 Irimia JM, Tagliabracci VS, Meyer CM, Segvich DM, DePaoli-Roach AA, Roach PJ. Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice. The Journal of Biological Chemistry. 290: 22686-98. PMID 26216881 DOI: 10.1074/Jbc.M115.673897  0.789
2015 DePaoli-Roach AA, Contreras CJ, Segvich DM, Heiss C, Ishihara M, Azadi P, Roach PJ. Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease. The Journal of Biological Chemistry. 290: 841-50. PMID 25416783 DOI: 10.1074/Jbc.M114.607796  0.68
2015 Chikwana VM, Khanna M, Baskaran S, Tagliabracci VS, Contreras CJ, DePaoli-Roach A, Roach PJ, Hurley TD. Correction: Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase (Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 52 (20976-20981) DOI: 10.1073/pnas.1310106111) Proceedings of the National Academy of Sciences of the United States of America. 112: E2264. DOI: 10.1073/Pnas.1506041112  0.764
2014 Garyali P, Segvich DM, DePaoli-Roach AA, Roach PJ. Protein degradation and quality control in cells from laforin and malin knockout mice. The Journal of Biological Chemistry. 289: 20606-14. PMID 24914213 DOI: 10.1074/Jbc.M114.580167  0.627
2014 Coate KC, Kraft G, Moore MC, Smith MS, Ramnanan C, Irimia JM, Roach PJ, Farmer B, Neal DW, Williams P, Cherrington AD. Hepatic glucose uptake and disposition during short-term high-fat vs. high-fructose feeding. American Journal of Physiology. Endocrinology and Metabolism. 307: E151-60. PMID 24865981 DOI: 10.1152/Ajpendo.00083.2014  0.369
2014 Ruiz R, Jideonwo V, Ahn M, Surendran S, Tagliabracci VS, Hou Y, Gamble A, Kerner J, Irimia-Dominguez JM, Puchowicz MA, DePaoli-Roach A, Hoppel C, Roach P, Morral N. Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver. The Journal of Biological Chemistry. 289: 5510-7. PMID 24398675 DOI: 10.1074/Jbc.M113.541110  0.754
2013 Chikwana VM, Khanna M, Baskaran S, Tagliabracci VS, Contreras CJ, DePaoli-Roach A, Roach PJ, Hurley TD. Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America. 110: 20976-81. PMID 24324135 DOI: 10.1073/Pnas.1310106111  0.797
2013 Pederson BA, Turnbull J, Epp JR, Weaver SA, Zhao X, Pencea N, Roach PJ, Frankland PW, Ackerley CA, Minassian BA. Inhibiting glycogen synthesis prevents Lafora disease in a mouse model. Annals of Neurology. 74: 297-300. PMID 23913475 DOI: 10.1002/Ana.23899  0.329
2013 Coate KC, Smith MS, Shiota M, Irimia JM, Roach PJ, Farmer B, Williams PE, Moore MC. Hepatic glucose metabolism in late pregnancy: normal versus high-fat and -fructose diet. Diabetes. 62: 753-61. PMID 23223020 DOI: 10.2337/Db12-0875  0.322
2013 Coate KC, Kraft G, Irimia JM, Smith MS, Farmer B, Neal DW, Roach PJ, Shiota M, Cherrington AD. Portal vein glucose entry triggers a coordinated cellular response that potentiates hepatic glucose uptake and storage in normal but not high-fat/high-fructose-fed dogs. Diabetes. 62: 392-400. PMID 23028137 DOI: 10.2337/Db12-0417  0.372
2013 Winnick JJ, An Z, Kraft G, Ramnanan CJ, Irimia JM, Smith M, Lautz M, Roach PJ, Cherrington AD. Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion. Diabetes. 62: 96-101. PMID 22923473 DOI: 10.2337/Db11-1773  0.342
2013 Roach PJ, Depaoli-Roach AA. Glycogen metabolism and lafora disease Protein Tyrosine Phosphatase Control of Metabolism. 239-262. DOI: 10.1007/978-1-4614-7855-3_13  0.534
2012 Roach PJ, Depaoli-Roach AA, Hurley TD, Tagliabracci VS. Glycogen and its metabolism: some new developments and old themes. The Biochemical Journal. 441: 763-87. PMID 22248338 DOI: 10.1042/Bj20111416  0.81
2012 DePaoli-Roach AA, Segvich DM, Meyer CM, Rahimi Y, Worby CA, Gentry MS, Roach PJ. Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity. Human Molecular Genetics. 21: 1604-10. PMID 22186021 DOI: 10.1093/Hmg/Ddr598  0.635
2011 Roach PJ. Are there errors in glycogen biosynthesis and is laforin a repair enzyme? Febs Letters. 585: 3216-8. PMID 21930129 DOI: 10.1016/J.Febslet.2011.09.009  0.446
2011 Jiang S, Wells CD, Roach PJ. Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1. Biochemical and Biophysical Research Communications. 413: 420-5. PMID 21893048 DOI: 10.1016/J.Bbrc.2011.08.106  0.583
2011 Baskaran S, Chikwana VM, Contreras CJ, Davis KD, Wilson WA, DePaoli-Roach AA, Roach PJ, Hurley TD. Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen. The Journal of Biological Chemistry. 286: 33999-4006. PMID 21835915 DOI: 10.1074/Jbc.M111.264531  0.759
2011 Turnbull J, DePaoli-Roach AA, Zhao X, Cortez MA, Pencea N, Tiberia E, Piliguian M, Roach PJ, Wang P, Ackerley CA, Minassian BA. PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease. Plos Genetics. 7: e1002037. PMID 21552327 DOI: 10.1371/Journal.Pgen.1002037  0.587
2011 Tagliabracci VS, Heiss C, Karthik C, Contreras CJ, Glushka J, Ishihara M, Azadi P, Hurley TD, DePaoli-Roach AA, Roach PJ. Phosphate incorporation during glycogen synthesis and Lafora disease. Cell Metabolism. 13: 274-82. PMID 21356517 DOI: 10.1016/J.Cmet.2011.01.017  0.815
2011 Winnick JJ, An Z, Ramnanan CJ, Smith M, Irimia JM, Neal DW, Moore MC, Roach PJ, Cherrington AD. Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver. Diabetes. 60: 398-407. PMID 21270252 DOI: 10.2337/Db10-0592  0.399
2011 Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism (Journal of Biological Chemistry (2010) 285, (34960-34971)) Journal of Biological Chemistry. 286: 39673. DOI: 10.1074/Jbc.A110.150839  0.778
2011 Roach PJ, Skurat AV, Harris RA. Regulation of Glycogen Metabolism Comprehensive Physiology. 609-647. DOI: 10.1002/Cphy.Cp070219  0.441
2010 Rivera N, Ramnanan CJ, An Z, Farmer T, Smith M, Farmer B, Irimia JM, Snead W, Lautz M, Roach PJ, Cherrington AD. Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs. The Journal of Clinical Investigation. 120: 4425-35. PMID 21084754 DOI: 10.1172/Jci40919  0.357
2010 Baskaran S, Roach PJ, DePaoli-Roach AA, Hurley TD. Structural basis for glucose-6-phosphate activation of glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America. 107: 17563-8. PMID 20876143 DOI: 10.1073/Pnas.1006340107  0.82
2010 An Z, Winnick JJ, Farmer B, Neal D, Lautz M, Irimia JM, Roach PJ, Cherrington AD. A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo. Diabetes. 59: 2999-3007. PMID 20823104 DOI: 10.2337/Db10-0138  0.344
2010 Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism. The Journal of Biological Chemistry. 285: 34960-71. PMID 20810658 DOI: 10.1074/Jbc.M110.150839  0.8
2010 Tagliabracci VS, Roach PJ. Insights into the mechanism of polysaccharide dephosphorylation by a glucan phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 107: 15312-3. PMID 20724661 DOI: 10.1073/Pnas.1010573107  0.623
2010 DePaoli-Roach AA, Tagliabracci VS, Segvich DM, Meyer CM, Irimia JM, Roach PJ. Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin. The Journal of Biological Chemistry. 285: 25372-81. PMID 20538597 DOI: 10.1074/Jbc.M110.148668  0.771
2010 Wilson WA, Roach PJ, Montero M, Baroja-Fernández E, Muñoz FJ, Eydallin G, Viale AM, Pozueta-Romero J. Regulation of glycogen metabolism in yeast and bacteria. Fems Microbiology Reviews. 34: 952-85. PMID 20412306 DOI: 10.1111/J.1574-6976.2010.00220.X  0.333
2010 Ramnanan CJ, Edgerton DS, Rivera N, Irimia-Dominguez J, Farmer B, Neal DW, Lautz M, Donahue EP, Meyer CM, Roach PJ, Cherrington AD. Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo. Diabetes. 59: 1302-11. PMID 20185816 DOI: 10.2337/Db09-1625  0.364
2010 Irimia JM, Meyer CM, Peper CL, Zhai L, Bock CB, Previs SF, McGuinness OP, DePaoli-Roach A, Roach PJ. Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice. The Journal of Biological Chemistry. 285: 12851-61. PMID 20178984 DOI: 10.1074/Jbc.M110.106534  0.632
2010 Douillard-Guilloux G, Raben N, Takikita S, Ferry A, Vignaud A, Guillet-Deniau I, Favier M, Thurberg BL, Roach PJ, Caillaud C, Richard E. Restoration of muscle functionality by genetic suppression of glycogen synthesis in a murine model of Pompe disease. Human Molecular Genetics. 19: 684-96. PMID 19959526 DOI: 10.1093/Hmg/Ddp535  0.392
2009 Heyen CA, Tagliabracci VS, Zhai L, Roach PJ. Characterization of mouse UDP-glucose pyrophosphatase, a Nudix hydrolase encoded by the Nudt14 gene. Biochemical and Biophysical Research Communications. 390: 1414-8. PMID 19896456 DOI: 10.1016/J.Bbrc.2009.11.007  0.722
2008 Tagliabracci VS, Girard JM, Segvich D, Meyer C, Turnbull J, Zhao X, Minassian BA, Depaoli-Roach AA, Roach PJ. Abnormal metabolism of glycogen phosphate as a cause for Lafora disease. The Journal of Biological Chemistry. 283: 33816-25. PMID 18852261 DOI: 10.1074/Jbc.M807428200  0.797
2008 Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, ... ... Roach PJ, et al. A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. Plos Medicine. 5: e27. PMID 18232732 DOI: 10.1371/Journal.Pmed.0050027  0.611
2008 Roach PJ. Biosynthesis of glycogen Carbohydrates in Chemistry and Biology. 3: 349-361. DOI: 10.1002/9783527618255.ch59  0.312
2007 Tagliabracci VS, Turnbull J, Wang W, Girard JM, Zhao X, Skurat AV, Delgado-Escueta AV, Minassian BA, Depaoli-Roach AA, Roach PJ. Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 19262-6. PMID 18040046 DOI: 10.1073/Pnas.0707952104  0.794
2007 Wang W, Lohi H, Skurat AV, DePaoli-Roach AA, Minassian BA, Roach PJ. Glycogen metabolism in tissues from a mouse model of Lafora disease. Archives of Biochemistry and Biophysics. 457: 264-9. PMID 17118331 DOI: 10.1016/J.Abb.2006.10.017  0.674
2006 Skurat AV, Dietrich AD, Roach PJ. Interaction between glycogenin and glycogen synthase. Archives of Biochemistry and Biophysics. 456: 93-7. PMID 17055998 DOI: 10.1016/J.Abb.2006.09.024  0.412
2006 Wang W, Parker GE, Skurat AV, Raben N, DePaoli-Roach AA, Roach PJ. Relationship between glycogen accumulation and the laforin dual specificity phosphatase. Biochemical and Biophysical Research Communications. 350: 588-92. PMID 17022935 DOI: 10.1016/J.Bbrc.2006.09.091  0.647
2006 Hurley TD, Walls C, Bennett JR, Roach PJ, Wang M. Direct detection of glycogenin reaction products during glycogen initiation. Biochemical and Biophysical Research Communications. 348: 374-8. PMID 16889748 DOI: 10.1016/J.Bbrc.2006.07.106  0.609
2006 Parker GE, Pederson BA, Obayashi M, Schroeder JM, Harris RA, Roach PJ. Gene expression profiling of mice with genetically modified muscle glycogen content. The Biochemical Journal. 395: 137-45. PMID 16356168 DOI: 10.1042/Bj20051456  0.399
2005 Pederson BA, Schroeder JM, Parker GE, Smith MW, DePaoli-Roach AA, Roach PJ. Glucose metabolism in mice lacking muscle glycogen synthase. Diabetes. 54: 3466-73. PMID 16306363 DOI: 10.2337/Diabetes.54.12.3466  0.657
2005 Wilson WA, Skurat AV, Probst B, de Paoli-Roach A, Roach PJ, Rutter J. Control of mammalian glycogen synthase by PAS kinase. Proceedings of the National Academy of Sciences of the United States of America. 102: 16596-601. PMID 16275910 DOI: 10.1073/Pnas.0508481102  0.449
2005 Torija MJ, Novo M, Lemassu A, Wilson W, Roach PJ, François J, Parrou JL. Glycogen synthesis in the absence of glycogenin in the yeast Saccharomyces cerevisiae. Febs Letters. 579: 3999-4004. PMID 16004992 DOI: 10.1016/J.Febslet.2005.06.007  0.353
2005 Pederson BA, Cope CR, Irimia JM, Schroeder JM, Thurberg BL, Depaoli-Roach AA, Roach PJ. Mice with elevated muscle glycogen stores do not have improved exercise performance. Biochemical and Biophysical Research Communications. 331: 491-6. PMID 15850786 DOI: 10.1016/J.Bbrc.2005.03.206  0.603
2005 Hurley TD, Stout S, Miner E, Zhou J, Roach PJ. Requirements for catalysis in mammalian glycogenin. The Journal of Biological Chemistry. 280: 23892-9. PMID 15849187 DOI: 10.1074/Jbc.M502344200  0.663
2005 de Paula RM, Wilson WA, Roach PJ, Terenzi HF, Bertolini MC. Biochemical characterization of Neurospora crassa glycogenin (GNN), the self-glucosylating initiator of glycogen synthesis. Febs Letters. 579: 2208-14. PMID 15811343 DOI: 10.1016/J.Febslet.2005.02.075  0.362
2005 Wilson WA, Wang Z, Roach PJ. Regulation of yeast glycogen phosphorylase by the cyclin-dependent protein kinase Pho85p. Biochemical and Biophysical Research Communications. 329: 161-7. PMID 15721288 DOI: 10.1016/J.Bbrc.2005.01.106  0.48
2005 Pederson BA, Cope CR, Schroeder JM, Smith MW, Irimia JM, Thurberg BL, DePaoli-Roach AA, Roach PJ. Exercise capacity of mice genetically lacking muscle glycogen synthase: in mice, muscle glycogen is not essential for exercise. The Journal of Biological Chemistry. 280: 17260-5. PMID 15711014 DOI: 10.1074/Jbc.M410448200  0.596
2005 de Paula RM, Wilson WA, Terenzi HF, Roach PJ, Bertolini MC. GNN is a self-glucosylating protein involved in the initiation step of glycogen biosynthesis in Neurospora crassa. Archives of Biochemistry and Biophysics. 435: 112-24. PMID 15680913 DOI: 10.1016/J.Abb.2004.12.009  0.45
2004 Wang W, Roach PJ. Glycogen and related polysaccharides inhibit the laforin dual-specificity protein phosphatase. Biochemical and Biophysical Research Communications. 325: 726-30. PMID 15541350 DOI: 10.1016/J.Bbrc.2004.10.083  0.413
2004 Pederson BA, Chen H, Schroeder JM, Shou W, DePaoli-Roach AA, Roach PJ. Abnormal cardiac development in the absence of heart glycogen. Molecular and Cellular Biology. 24: 7179-87. PMID 15282316 DOI: 10.1128/Mcb.24.16.7179-7187.2004  0.588
2004 Wilson WA, Hughes WE, Tomamichel W, Roach PJ. Increased glycogen storage in yeast results in less branched glycogen. Biochemical and Biophysical Research Communications. 320: 416-23. PMID 15219844 DOI: 10.1016/J.Bbrc.2004.05.180  0.384
2004 Pederson BA, Wilson WA, Roach PJ. Glycogen synthase sensitivity to glucose-6-P is important for controlling glycogen accumulation in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 279: 13764-8. PMID 14742447 DOI: 10.1074/Jbc.M312335200  0.328
2003 DePaoli-Roach AA, Vilardo PG, Kim JH, Mavila N, Vemuri B, Roach PJ. Determination of mammalian glycogen synthase phosphatase activity. Methods in Enzymology. 366: 17-34. PMID 14674236 DOI: 10.1016/S0076-6879(03)66002-7  0.624
2003 Pederson BA, Csitkovits AG, Simon R, Schroeder JM, Wang W, Skurat AV, Roach PJ. Overexpression of glycogen synthase in mouse muscle results in less branched glycogen. Biochemical and Biophysical Research Communications. 305: 826-30. PMID 12767905 DOI: 10.1016/S0006-291X(03)00862-3  0.433
2003 DePaoli-Roach AA, Vilardo PG, Kim JH, Mavila N, Vemuri B, Roach PJ. [2] Determination of Mammalian Glycogen Synthase Phosphatase Activity Methods in Enzymology. 366: 17-34. DOI: 10.1016/S0076-6879(03)66002-7  0.586
2002 Wilson WA, Roach PJ. Nutrient-regulated protein kinases in budding yeast. Cell. 111: 155-8. PMID 12408859 DOI: 10.1016/S0092-8674(02)01043-7  0.423
2002 Wilson WA, Wang Z, Roach PJ. Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Molecular & Cellular Proteomics : McP. 1: 232-42. PMID 12096123 DOI: 10.1074/Mcp.M100024-Mcp200  0.379
2002 Gibbons BJ, Roach PJ, Hurley TD. Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin. Journal of Molecular Biology. 319: 463-77. PMID 12051921 DOI: 10.1016/S0022-2836(02)00305-4  0.654
2002 Roach PJ. Glycogen and its metabolism. Current Molecular Medicine. 2: 101-20. PMID 11949930 DOI: 10.2174/1566524024605761  0.463
2002 Wilson WA, Wang Z, Roach PJ. Analysis of respiratory mutants reveals new aspects of the control of glycogen accumulation by the cyclin-dependent protein kinase Pho85p. Febs Letters. 515: 104-8. PMID 11943203 DOI: 10.1016/S0014-5793(02)02448-1  0.443
2002 Skurat AV, Dietrich AD, Zhai L, Roach PJ. GNIP, a novel protein that binds and activates glycogenin, the self-glucosylating initiator of glycogen biosynthesis. The Journal of Biological Chemistry. 277: 19331-8. PMID 11916970 DOI: 10.1074/Jbc.M201190200  0.372
2002 Hanashiro I, Roach PJ. Mutations of muscle glycogen synthase that disable activation by glucose 6-phosphate. Archives of Biochemistry and Biophysics. 397: 286-92. PMID 11795884 DOI: 10.1006/Abbi.2001.2623  0.501
2001 Wang Z, Wilson WA, Fujino MA, Roach PJ. The yeast cyclins Pc16p and Pc17p are involved in the control of glycogen storage by the cyclin-dependent protein kinase Pho85p. Febs Letters. 506: 277-80. PMID 11602261 DOI: 10.1016/S0014-5793(01)02914-3  0.448
2001 Wang Z, Wilson WA, Fujino MA, Roach PJ. Antagonistic controls of autophagy and glycogen accumulation by snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase pho85p Molecular and Cellular Biology. 21: 5742-5752. PMID 11486014 DOI: 10.1128/Mcb.21.17.5742-5752.2001  0.41
2001 Zhai L, Schroeder J, Skurat AV, Roach PJ. Do rodents have a gene encoding glycogenin-2, the liver isoform of the self-glucosylating initiator of glycogen synthesis? Iubmb Life. 51: 87-91. PMID 11463169 DOI: 10.1080/15216540117315  0.351
2001 Raben N, Danon M, Lu N, Lee E, Shliselfeld L, Skurat AV, Roach PJ, Lawrence JC, Musumeci O, Shanske S, DiMauro S, Plotz P. Surprises of genetic engineering: a possible model of polyglucosan body disease. Neurology. 56: 1739-45. PMID 11425943 DOI: 10.1212/Wnl.56.12.1739  0.322
2001 Dubois T, Kerai P, Zemlickova E, Howell S, Jackson TR, Venkateswarlu K, Cullen PJ, Theibert AB, Larose L, Roach PJ, Aitken A. Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins Journal of Biological Chemistry. 276: 18757-18764. PMID 11278595 DOI: 10.1074/Jbc.M010005200  0.361
2000 Skurat AV, Dietrich AD, Roach PJ. Glycogen synthase sensitivity to insulin and glucose-6-phosphate is mediated by both NH2- and COOH-terminal phosphorylation sites Diabetes. 49: 1096-1100. PMID 10909964 DOI: 10.2337/Diabetes.49.7.1096  0.454
2000 Pederson BA, Cheng C, Wilson WA, Roach PJ. Regulation of glycogen synthase: Identification of residues involved in regulation by the allosteric ligand glucose-6-P and by phosphorylation Journal of Biological Chemistry. 275: 27753-27761. PMID 10874034 DOI: 10.1074/Jbc.M003342200  0.445
2000 Zhai L, Mu J, Zong H, DePaoli-Roach AA, Roach PJ. Structure and chromosomal localization of the human glycogenin-2 gene GYG2 Gene. 242: 229-235. PMID 10721716 DOI: 10.1016/S0378-1119(99)00520-X  0.551
2000 Azpiazu I, Manchester J, Skurat AV, Roach PJ, Lawrence JC. Control of glycogen synthesis is shared between glucose transport and glycogen synthase in skeletal muscle fibers. American Journal of Physiology. Endocrinology and Metabolism. 278: E234-43. PMID 10662707 DOI: 10.1152/Ajpendo.2000.278.2.E234  0.34
1999 Wilson WA, Mahrenholz AM, Roach PJ. Substrate targeting of the yeast cyclin-dependent kinase Pho85p by the cyclin Pcl10p Molecular and Cellular Biology. 19: 7020-7030. PMID 10490639 DOI: 10.1128/Mcb.19.10.7020  0.454
1999 Lin A, Mu J, Yang J, Roach PJ. Self-glucosylation of glycogenin, the initiator of glycogen biosynthesis, involves an inter-subunit reaction Archives of Biochemistry and Biophysics. 363: 163-170. PMID 10049511 DOI: 10.1006/Abbi.1998.1073  0.352
1998 Roach PJ, Cheng C, Huang D, Lin A, Mu J, Skurat AV, Wilson W, Zhai L. Novel aspects of the regulation of glycogen storage. Journal of Basic and Clinical Physiology and Pharmacology. 9: 139-152. PMID 10212831 DOI: 10.1515/Jbcpp.1998.9.2-4.139  0.346
1998 Mu J, Roach PJ. Characterization of human glycogenin-2, a self-glucosylating initiator of liver glycogen metabolism Journal of Biological Chemistry. 273: 34850-34856. PMID 9857012 DOI: 10.1074/Jbc.273.52.34850  0.32
1998 Longenecker KL, Roach PJ, Hurley TD. Crystallographic studies of casein kinase I δ: Toward a structural understanding of auto-inhibition Acta Crystallographica Section D: Biological Crystallography. 54: 473-475. PMID 9761932 DOI: 10.1107/S0907444997011724  0.625
1998 Huang D, Moffat J, Wilson WA, Moore L, Cheng C, Roach PJ, Andrews B. Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10. Molecular and Cellular Biology. 18: 3289-99. PMID 9584169 DOI: 10.1128/Mcb.18.6.3289  0.472
1997 Mu J, Skurat AV, Roach PJ. Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis Journal of Biological Chemistry. 272: 27589-27597. PMID 9346895 DOI: 10.1074/Jbc.272.44.27589  0.375
1997 Huang D, Wilson WA, Roach PJ. Glucose-6-P control of glycogen synthase phosphorylation in yeast Journal of Biological Chemistry. 272: 22495-22501. PMID 9278401 DOI: 10.1074/Jbc.272.36.22495  0.468
1997 Skurat AV, Lim SS, Roach PJ. Glycogen biogenesis in rat 1 fibroblasts expressing rabbit muscle glycogenin European Journal of Biochemistry. 245: 147-155. PMID 9128736 DOI: 10.1111/J.1432-1033.1997.T01-1-00147.X  0.415
1997 Lawrence JC, Roach PJ. New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes. 46: 541-7. PMID 9075792 DOI: 10.2337/Diab.46.4.541  0.445
1997 Lawrence JC, Skurat AV, Roach PJ, Azpiazu I, Manchester J. Glycogen synthase: activation by insulin and effect of transgenic overexpression in skeletal muscle. Biochemical Society Transactions. 25: 14-9. PMID 9056834 DOI: 10.1042/Bst0250014  0.365
1997 Cheng C, Huang D, Roach PJ. Yeast PIG genes: PIG1 encodes a putative type 1 phosphatase subunit that interacts with the yeast glycogen synthase Gsy2p Yeast. 13: 1-8. PMID 9046081 DOI: 10.1002/(Sici)1097-0061(199701)13:1<1::Aid-Yea49>3.0.Co;2-F  0.364
1996 Mu J, Cheng C, Roach PJ. Initiation of glycogen synthesis in yeast. Requirement of multiple tyrosine residues for function of the self-glucosylating Glg proteins in vivo Journal of Biological Chemistry. 271: 26554-26560. PMID 8900126 DOI: 10.1074/Jbc.271.43.26554  0.386
1996 Manchester J, Skurat AV, Roach P, Hauschka SD, Lawrence JC. Increased glycogen accumulation in transgenic mice overexpressing glycogen synthase in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 93: 10707-11. PMID 8855244 DOI: 10.1073/Pnas.93.20.10707  0.419
1996 Huang D, Farkas I, Roach PJ. Pho85p, a cyclin-dependent protein kinase, and the Snf1p protein kinase act antagonistically to control glycogen accumulation in Saccharomyces cerevisiae Molecular and Cellular Biology. 16: 4357-4365. PMID 8754836 DOI: 10.1128/Mcb.16.8.4357  0.478
1996 Longenecker KL, Roach PJ, Hurley TD. Three-dimensional structure of mammalian casein kinase I: Molecular basis for phosphate recognition Journal of Molecular Biology. 257: 618-631. PMID 8648628 DOI: 10.1006/Jmbi.1996.0189  0.658
1996 Skurat AV, Peng HL, Chang HY, Cannon JF, Roach PJ. Rate-determining steps in the biosynthesis of glycogen in COS cells Archives of Biochemistry and Biophysics. 328: 283-288. PMID 8645005 DOI: 10.1006/Abbi.1996.0174  0.461
1996 Skurat AV, Roach PJ. Multiple mechanisms for the phosphorylation of C-terminal regulatory sites in rabbit muscle glycogen synthase expressed in COS cells Biochemical Journal. 313: 45-50. PMID 8546708 DOI: 10.1042/Bj3130045  0.384
1996 Skurat AV, Dietrich AD, Roach PJ. Glycogen synthesis in RAT-1 fibroblasts expressing rabbit muscle glycogenin Faseb Journal. 10.  0.314
1995 Cheng C, Mu J, Farkas I, Huang D, Goebl MG, Roach PJ. Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae Molecular and Cellular Biology. 15: 6632-6640. PMID 8524228 DOI: 10.1128/Mcb.15.12.6632  0.415
1995 Cao YJ, Steinrauf LK, Roach PJ. Mechanism of Glycogenin Self-Glucosylation Archives of Biochemistry and Biophysics. 319: 293-298. PMID 7771798 DOI: 10.1006/Abbi.1995.1295  0.371
1995 Zhai L, Graves PR, Robinson LC, Italiano M, Culbertson MR, Rowles J, Cobb MH, DePaoli-Roach AA, Roach PJ. Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes. The Journal of Biological Chemistry. 270: 12717-24. PMID 7759525 DOI: 10.1074/Jbc.270.21.12717  0.655
1995 Skurat AV, Roach PJ. Phosphorylation of sites 3a and 3b (Ser640 and Ser644) in the control of rabbit muscle glycogen synthase Journal of Biological Chemistry. 270: 12491-12497. PMID 7759494 DOI: 10.1074/Jbc.270.21.12491  0.381
1995 Wang QM, Vik TA, Ryder JW, Roach PJ. Phosphorylation and Activation of p90rsk by Glycogen Synthase Kinase-3 Biochemical and Biophysical Research Communications. 208: 796-801. PMID 7695638 DOI: 10.1006/Bbrc.1995.1407  0.423
1995 Hardy TA, Wu D, Roach PJ. Novel Saccharomyces cerevisiae Gene, MRK1, Encoding a Putative Protein Kinase with Similarity to Mammalian Glycogen Synthase Kinase-3 and Drosophila Zeste-White3/Shaggy Biochemical and Biophysical Research Communications. 208: 728-734. PMID 7695629 DOI: 10.1006/Bbrc.1995.1398  0.408
1995 Graves PR, Roach PJ. Role of COOH-terminal phosphorylation in the regulation of casein kinase Iδ Journal of Biological Chemistry. 270: 21689-21694. PMID 7665585 DOI: 10.1074/Jbc.270.37.21689  0.436
1995 Wang QM, Guan KL, Roach PJ, DePaoli-Roach AA. Phosphorylation and activation of the ATP-Mg-dependent protein phosphatase by the mitogen-activated protein kinase Journal of Biological Chemistry. 270: 18352-18358. PMID 7629158 DOI: 10.1074/Jbc.270.31.18352  0.662
1994 Wang QM, Park IK, Fiol CJ, Roach PJ, DePaoli-Roach AA. Isoform differences in substrate recognition by glycogen synthase kinases 3α and 3β in the phosphorylation of phosphatase inhibitor 2 Biochemistry. 33: 143-147. PMID 8286331 DOI: 10.1021/Bi00167A018  0.642
1994 Puziss JW, Hardy TA, Johnson RB, Roach PJ, Hieter P. MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase Molecular and Cellular Biology. 14: 831-839. PMID 8264650 DOI: 10.1128/Mcb.14.1.831  0.301
1994 Wang QM, Roach PJ, Fiol CJ. Use of a Synthetic Peptide as a Selective Substrate for Glycogen Synthase Kinase 3 Analytical Biochemistry. 220: 397-402. PMID 7978284 DOI: 10.1006/Abio.1994.1356  0.411
1994 Hardy TA, Huang D, Roach PJ. Interactions between cAMP-dependent and SNF1 protein kinases in the control of glycogen accumulation in Saccharomyces cerevisiae Journal of Biological Chemistry. 269: 27907-27913. PMID 7961723  0.396
1994 Wang QM, Fiol CJ, DePaoli-Roach AA, Roach PJ. Glycogen synthase kinase-3β is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation Journal of Biological Chemistry. 269: 14566-14574. PMID 7514173  0.646
1993 Graves PR, Haas DW, Hagedorn CH, DePaoli-Roach AA, Roach PJ. Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis Journal of Biological Chemistry. 268: 6394-6401. PMID 8454611  0.618
1993 Cao Y, Skurat AV, DePaoli-Roach AA, Roach PJ. Initiation of glycogen synthesis: Control of glycogenin by glycogen phosphorylase Journal of Biological Chemistry. 268: 21717-21721. PMID 8408025  0.623
1993 Zhang WM, Depaoliroach AA, Roach PJ. Mechanisms of Multisite Phosphorylation and Inactivation of Rabbit Muscle Glycogen Synthase Archives of Biochemistry and Biophysics. 304: 219-225. PMID 8391782 DOI: 10.1006/Abbi.1993.1342  0.477
1993 Skurat AV, Cao Y, Roach PJ. Glucose control of rabbit skeletal muscle glycogenin expressed in COS cells Journal of Biological Chemistry. 268: 14701-14707. PMID 8325849  0.312
1993 Cao Y, Mahrenholz AM, DePaoli-Roach AA, Roach PJ. Characterization of rabbit skeletal muscle glycogenin: Tyrosine 194 is essential for function Journal of Biological Chemistry. 268: 14687-14693. PMID 8325847  0.642
1993 Wang Y, Roach PJ. Inactivation of rabbit muscle glycogen synthase by glycogen synthase kinase-3: Dominant role of the phosphorylation of SER-640 (site 3a) Journal of Biological Chemistry. 268: 23876-23880. PMID 8226927  0.332
1993 Hardy TA, Roach PJ. Control of yeast glycogen synthase-2 by COOH-terminal phosphorylation Journal of Biological Chemistry. 268: 23799-23805. PMID 8226915  0.359
1992 Robinson LC, Hubbard EJ, Graves PR, DePaoli-Roach AA, Roach PJ, Kung C, Haas DW, Hagedorn CH, Goebl M, Culbertson MR. Yeast casein kinase I homologues: an essential gene pair. Proceedings of the National Academy of Sciences of the United States of America. 89: 28-32. PMID 1729698 DOI: 10.1073/Pnas.89.1.28  0.631
1992 Zhai L, Graves PR, Longenecker KL, DePaoli-Roach AA, Roach PJ. Recombinant rabbit muscle casein kinase I α is inhibited by heparin and activated by polylysine Biochemical and Biophysical Research Communications. 189: 944-949. PMID 1472067 DOI: 10.1016/0006-291X(92)92295-9  0.665
1992 Colbran JL, Roach PJ, Fiol CJ, Dixon JE, Andrisani OM, Corbin JD. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 1277-1282. PMID 1338414 DOI: 10.1139/O92-174  0.582
1992 Viskupic E, Cao Y, Zhang W, Cheng C, DePaoli-Roach AA, Roach PJ. Rabbit skeletal muscle glycogenin: Molecular cloning and production of fully functional protein in Escherichia coli Journal of Biological Chemistry. 267: 25759-25763. PMID 1281472  0.611
1991 Roach PJ, Cao Y, Corbett CA, DePaoli-Roach AA, Farkas I, Fiol CJ, Flotow H, Graves PR, Hardy TA, Hrubey TW. Glycogen metabolism and signal transduction in mammals and yeast. Advances in Enzyme Regulation. 31: 101-20. PMID 1652188 DOI: 10.1016/0065-2571(91)90011-A  0.675
1990 Hrubey TW, Roach PJ. Phosphoserine in peptide substrates can specify casein kinase II action Biochemical and Biophysical Research Communications. 172: 190-196. PMID 2171517 DOI: 10.1016/S0006-291X(05)80192-5  0.369
1990 Roach PJ. Control of glycogen synthase by hierarchal protein phosphorylation Faseb Journal. 4: 2961-2968. PMID 2168324 DOI: 10.1096/Fasebj.4.12.2168324  0.432
1990 Farkas I, Hardy TA, DePaoli-Roach AA, Roach PJ. Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene Journal of Biological Chemistry. 265: 20879-20886. PMID 2123485  0.596
1989 Armstrong DJ, Roach PJ. Glycogen synthase turnover and phosphorylation in rat H4IIE hepatoma cells Archives of Biochemistry and Biophysics. 275: 16-22. PMID 2510600 DOI: 10.1016/0003-9861(89)90344-5  0.326
1989 Zhang W, Browner MF, Fletterick RJ, DePaoli-Roach AA, Roach PJ. Primary structure of rabbit skeletal muscle glycogen synthase deduced from cDNA clones Faseb Journal. 3: 2532-2536. PMID 2509275 DOI: 10.1096/Fasebj.3.13.2509275  0.614
1989 Flotow H, Roach PJ. Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase Journal of Biological Chemistry. 264: 9126-9128. PMID 2498326  0.364
1988 Wang Y, Fiol CJ, DePaoli-Roach AA, Bell AW, Hermodson MA, Roach PJ. Identification of phosphorylation sites in peptides using a gas-phase sequencer Analytical Biochemistry. 174: 537-547. PMID 3239755 DOI: 10.1016/0003-2697(88)90053-X  0.582
1988 Mahrenholz AM, Votaw P, Roach PJ, Depaoli-Roach AA, Zioncheck TF, Harrison ML, Geahlen RL. Phosphorylation of glycogen synthase by a bovine thymus protein-tyrosine kinase, p40 Biochemical and Biophysical Research Communications. 155: 52-58. PMID 3137939 DOI: 10.1016/S0006-291X(88)81048-9  0.655
1988 Corvera S, Roach PJ, DePaoli-Roach AA, Czech MP. Insulin action inhibits insulin-like growth factor-II (IGF-II) receptor phosphorylation in H-35 hepatoma cells. IGF-II receptors isolated from insulin-treated cells exhibit enhanced in vitro phosphorylation by casein kinase II Journal of Biological Chemistry. 263: 3116-3122. PMID 2963823  0.572
1988 Fiol CJ, Haseman JH, Wang Y, Roach PJ, Roeske RW, Kowalczuk M, DePaoli-Roach AA. Phosphoserine as a recognition determinant for glycogen synthase kinase-3: Phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1 Archives of Biochemistry and Biophysics. 267: 797-802. PMID 2850771 DOI: 10.1016/0003-9861(88)90089-6  0.66
1987 Lee FT, Ahmad Z, DePaoli-Roach AA, Roach PJ. Multiple phosphorylation of mouse muscle glycogen synthase Archives of Biochemistry and Biophysics. 258: 615-620. PMID 3118813 DOI: 10.1016/0003-9861(87)90384-5  0.666
1987 Fiol CJ, Mahrenholz AM, Wang Y, Roeske RW, Roach PJ. Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3 Journal of Biological Chemistry. 262: 14042-14048. PMID 2820993  0.301
1986 DePaoli-Roach A, Roach PJ, Zucker KE, Smith SS. Selective phosphorylation of human DNA methyltransferase by protein kinase C Febs Letters. 197: 149-153. PMID 3949011 DOI: 10.1016/0014-5793(86)80316-7  0.612
1986 Wang Y, Camici M, Lee FT, Ahmad Z, DePaoli-Roach AA, Roach PJ. Multiple phosphorylation sites of rat liver glycogen synthase Bba - Molecular Cell Research. 888: 225-236. PMID 3091084 DOI: 10.1016/0167-4889(86)90025-X  0.686
1986 Corvera S, Davis RJ, Roach PJ, DePaoli-Roach A, Czech MP. Mechanism of receptor kinase action on membrane protein recycling Annals of the New York Academy of Sciences. 488: 419-429. PMID 3034121 DOI: 10.1111/J.1749-6632.1986.Tb54421.X  0.581
1986 Ahmad Z, Lee FT, DePaoli-Roach AA, Roach PJ. Heparin-activated protein kinase from rabbit muscle: Relationship to enzymes of the glycogen synthase kinase-3 category Archives of Biochemistry and Biophysics. 250: 329-335. PMID 3022646 DOI: 10.1016/0003-9861(86)90734-4  0.686
1986 Roach PJ. 12 Liver Glycogen Synthase Enzymes. 17: 499-539. DOI: 10.1016/S1874-6047(08)60437-0  0.422
1985 Haring HU, White MF, Kahn CR, Ahmad Z, DePaoli-Roach AA, Roach PJ. Interaction of the insulin receptor kinase with serine/threonine kinases in vitro Journal of Cellular Biochemistry. 28: 171-182. PMID 3001107 DOI: 10.1002/Jcb.240280209  0.645
1985 Roach P, Roach PJ, DePaoli-Roach AA. Phosphoprotein phosphatase inhibitor-2. Identification as a species of molecular weight 31,000 in rabbit muscle, liver, and other tissues Journal of Biological Chemistry. 260: 6314-6317. PMID 2987219  0.549
1985 Ahmad Z, DePaoli-Roach AA, Roach PJ. Novel heparin-activated protein kinase activity in rabbit skeletal muscle Federation Proceedings. 44. DOI: 10.1016/0014-5793(85)80199-X  0.692
1985 Lee FT, Ahmad Z, DePaoli-Roach AA, Roach PJ. Epinephrine control of multiple phosphorylation sites of glycogen synthase in mouse diaphragms Federation Proceedings. 44.  0.581
1984 Ciudad C, Camici M, Ahmad Z, Wang Y, DePaoli-Roach AA, Roach PJ. Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon European Journal of Biochemistry. 142: 511-520. PMID 6432531 DOI: 10.1111/J.1432-1033.1984.Tb08315.X  0.678
1984 Camici M, DePaoli-Roach AA, Roach PJ. Rabbit liver glycogen synthase. Purification and comparison of the properties of glucose-6-P-dependent and glucose-6-P-independent forms of the enzyme Journal of Biological Chemistry. 259: 3429-3434. PMID 6423631  0.606
1984 Ciudad C, DePaoli-Roach A, Roach PJ. Phosphorylation of glycogen synthase in isolated rabbit hepatocytes Bba - Molecular Cell Research. 804: 261-263. PMID 6326853 DOI: 10.1016/0167-4889(84)90158-7  0.66
1984 Ahmad Z, Camici M, DePaoli-Roach AA, Roach PJ. Glycogen synthase kinases. Classification of a rabbit liver casein and glycogen synthase kinase (casein kinase-1) as a distinct enzyme Journal of Biological Chemistry. 259: 3420-3428. PMID 6323424  0.654
1984 Camici M, Ahmad Z, DePaoli Roach AA, Roach PJ. Phosphorylation of rabbit liver glycogen synthase by multiple protein kinases Journal of Biological Chemistry. 259: 2466-2473. PMID 6321470  0.366
1984 Ahmad Z, Lee FT, DePaoli-Roach A, Roach PJ. Phosphorylation of glycogen synthase by the Ca2+- and phospholipid-activated protein kinase (protein kinase C) Journal of Biological Chemistry. 259: 8743-8747. PMID 6235216  0.394
1984 Ahmed Z, Lee FT, DePaoli-Roach AA, Roach PJ. Phosphorylation of glycogen synthase by the Ca2+ and phospholipid dependent protein kinase (protein kinase C) Federation Proceedings. 43.  0.597
1983 Roach PJ, Goldman M. Modification of glycogen synthase activity in isolated rat hepatocytes by tumor-promoting phorbol esters: Evidence for differential regulation of glycogen synthase and phosphorylase Proceedings of the National Academy of Sciences of the United States of America. 80: 7170-7172. PMID 6417664 DOI: 10.1073/Pnas.80.23.7170  0.347
1983 Lawrence JC, Hiken JF, DePaoli-Roach AA, Roach PJ. Hormonal control of glycogen synthase in rat hemidiaphragms. Effects of insulin and epinephrine on the distribution of phosphate between two cyanogen bromide fragments. The Journal of Biological Chemistry. 258: 10710-9. PMID 6411719  0.326
1983 DePaoli-Roach AA, Ahmad Z, Camici M, Lawrence JC, Roach PJ. Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Evidence for interactions among phosphorylation sites and the resolution of electrophoretically distinct forms of the subunit Journal of Biological Chemistry. 258: 10702-10709. PMID 6309812  0.635
1982 Camici M, DePaoli-Roach AA, Roach PJ. Rabbit liver glycogen synthase. Susceptibility of the enzyme subunit to proteolysis Journal of Biological Chemistry. 257: 9898-9901. PMID 6809751  0.621
1982 DePaoli-Roach AA, Roach PJ. Heparin inhibition and polyamine stimulation of a glycogen synthase kinase (PC0.7) from rabbit skeletal muscle Archives of Biochemistry and Biophysics. 217: 305-311. PMID 6289752 DOI: 10.1016/0003-9861(82)90506-9  0.646
1982 Ahmad Z, DePaoli-Roach AA, Roach PJ. Purification and characterization of a rabbit liver calmodulin-dependent protein kinase able to phosphorylate glycogen synthase Journal of Biological Chemistry. 257: 8348-8355. PMID 6282881  0.62
1982 Ahmad Z, DePaoli-Roach AA, Roach PJ. Rabbit liver glycogen synthase kinases. Characterization of a protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin Journal of Biological Chemistry. 257: 5873-5876. PMID 6279617  0.651
1982 DePaoli-Roach AA, Roach PJ. Heparin inhibition and polyamine stimulation of a rabbit muscle glycogen synthese kinase (PC0.7) Federation Proceedings. 41.  0.588
1982 Ahmad Z, DePaoli-Roach AA, Roach PJ. Calmodulin-stimulated glycogen synthase kinase from rabbit liver Federation Proceedings. 41.  0.581
1981 Depaoli-Roach AA, Bingham EW, Roach PJ. Phosphorylase kinase from rabbit skeletal muscle: Phosphorylation of κ-casein Archives of Biochemistry and Biophysics. 212: 229-236. PMID 7305404 DOI: 10.1016/0003-9861(81)90362-3  0.661
1981 DePaoli-Roach AA, Ahmad Z, Roach PJ. Characterization of a rabbit skeletal muscle protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin Journal of Biological Chemistry. 256: 8955-8962. PMID 6790548  0.658
1981 DePaoli-Roach AA, Roach PJ, Pham K, Kramer G, Hardesty B. Phosphorylation of glycogen synthase and of the β subunit of eukaryotic initiation factor two by a common protein kinase Journal of Biological Chemistry. 256: 8871-8874. PMID 6790546  0.627
1981 Roach PJ. Glycogen synthase and glycogen synthase kinases Current Topics in Cellular Regulation. 20: 45-105. PMID 6276084 DOI: 10.1016/B978-0-12-152820-1.50006-7  0.448
1979 Depaoli-Roach AA, Gibbs JB, Roach PJ. Calcium and calmodulin activation of muscle phosphorylase kinase. Effect of tryptic proteolysis Febs Letters. 105: 321-324. PMID 488359 DOI: 10.1016/0014-5793(79)80639-0  0.579
1979 DePaoli-Roach AA, Roach PJ, Larner J. Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Comparison of the actions of different protein kinases capable of catalyzing phosphorylation in vitro Journal of Biological Chemistry. 254: 12062-12068. PMID 115877  0.637
1979 Salavert A, Roach PJ, Guinovart JJ. Effect of partial tryptic proteolysis on the kinetic properties of rabbit muscle glycogen synthase Bba - Enzymology. 570: 231-238. PMID 115497 DOI: 10.1016/0005-2744(79)90143-8  0.318
1979 DePaoli-Roach AA, Roach PJ, Larner J. Rabbit skeletal muscle phosphorylase kinase. Comparison of glycogen synthase and phosphorylase as substrates Journal of Biological Chemistry. 254: 4212-4219. PMID 108271  0.618
1978 Roach PJ, DePaoli-Roach AA, Larner J. Ca2+-stimulated phosphorylation of muscle glycogen synthase by phosphorylase b kinase Journal of Cyclic Nucleotide Research. 4: 245-257. PMID 102668  0.589
1977 Roach PJ, Rosell-Perez M, Larner J. Muscle glycogen synthase in vivo state:. Effects of insulin administration on the chemical and kinetic properties of the purified enzyme Febs Letters. 80: 95-98. PMID 408195 DOI: 10.1016/0014-5793(77)80414-6  0.601
1977 Roach PJ, Larner J. Covalent phosphorylation in the regulation of glycogen synthase activity Molecular and Cellular Biochemistry. 15: 179-200. PMID 196178 DOI: 10.1007/Bf01734108  0.628
1976 Roach PJ, Takeda Y, Larner J. Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties Journal of Biological Chemistry. 251: 1913-1919. PMID 818081  0.342
1976 Roach PJ, Larner J. Rabbit skeletal muscle glycogen synthase. II. Enzyme phosphorylation state and effector concentrations as interacting control parameters Journal of Biological Chemistry. 251: 1920-1925. PMID 5435  0.374
1976 Roach PJ, Larner J. Regulation of glycogen synthase: A relation of enzymic properties with biological function Trends in Biochemical Sciences. 1: 110-112. DOI: 10.1016/0968-0004(76)90018-9  0.597
1975 Roach PJ, Warren KR, Atkinson DE. Uridine diphosphate glucose synthase from calf liver: determinants of enzyme activity in vitro. Biochemistry. 14: 5445-50. PMID 172124 DOI: 10.1021/Bi00696A010  0.64
1975 Atkinson DE, Roach PJ, Schwedes JS. Metabolite concentrations and concentration ratios in metabolic regulation. Advances in Enzyme Regulation. 13: 393-411. PMID 1976 DOI: 10.1016/0065-2571(75)90027-8  0.547
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