| Year |
Citation |
Score |
| 2024 |
Chagraoui J, Girard S, Mallinger L, Mayotte N, Tellechea MF, Sauvageau G. KBTBD4-mediated Reduction of MYC Is Critical For Hematopoietic Stem Cell Expansion Upon UM171 Treatment. Blood. PMID 38207291 DOI: 10.1182/blood.2023021342 |
0.461 |
|
| 2023 |
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, ... ... Sauvageau G, et al. CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216. Blood Advances. PMID 37729615 DOI: 10.1182/bloodadvances.2022008899 |
0.708 |
|
| 2023 |
Zhang YW, Velasco-Hernandez T, Mess J, Lalioti ME, Romero-Mulero MC, Obier N, Karantzelis N, Rettkowski J, Schönberger K, Karabacz N, Jäcklein K, Morishima T, Trincado JL, Romecin P, Martinez-Moreno A, ... ... Sauvageau G, et al. GPRC5C Drives Branched-Chain Amino Acid Metabolism in Leukemogenesis. Blood Advances. PMID 37639313 DOI: 10.1182/bloodadvances.2023010460 |
0.389 |
|
| 2022 |
Moison C, Spinella JF, Chagraoui J, Lavallee VP, Lehnertz B, Thiollier C, Boivin I, Mayotte N, MacRae T, Marinier A, Hébert J, Sauvageau G. HMGA2 expression defines a subset of AML with immature transcriptional signature and vulnerability to G2/M inhibition. Blood Advances. PMID 35797243 DOI: 10.1182/bloodadvances.2021005828 |
0.41 |
|
| 2022 |
Zhang YW, Mess J, Aizarani N, Mishra P, Johnson C, Romero-Mulero MC, Rettkowski J, Schönberger K, Obier N, Jäcklein K, Woessner NM, Lalioti ME, Velasco-Hernandez T, Sikora K, Wäsch R, ... ... Sauvageau G, et al. Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells. Nature Cell Biology. PMID 35725769 DOI: 10.1038/s41556-022-00931-x |
0.355 |
|
| 2022 |
Dumont-Lagacé M, Feghaly A, Meunier MC, Finney M, Van't Hof W, Masson Frenet E, Sauvageau G, Cohen S. UM171 Expansion of Cord Blood Improves Donor Availability and HLA Matching For All Patients, Including Minorities. Transplantation and Cellular Therapy. PMID 35311667 DOI: 10.1016/j.jtct.2022.03.016 |
0.33 |
|
| 2022 |
Ansari U, Tomellini E, Chagraoui J, Lehnertz B, Mayotte N, Bordeleau ME, Roux PP, Sauvageau G. CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells. Blood Advances. PMID 35286394 DOI: 10.1182/bloodadvances.2021006835 |
0.452 |
|
| 2022 |
He L, Arnold C, Thoma J, Rohde C, Kholmatov M, Garg S, Hsiao CC, Viol L, Zhang K, Sun R, Schmidt C, Janssen M, MacRae T, Huber K, Thiede C, ... ... Sauvageau G, et al. CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia. Embo Molecular Medicine. e14990. PMID 35253392 DOI: 10.15252/emmm.202114990 |
0.377 |
|
| 2021 |
Lehnertz B, Chagraoui J, MacRae T, Tomellini E, Corneau S, Mayotte N, Boivin I, Durand A, Gracias D, Sauvageau G. HLF Expression Defines the Human Hematopoietic Stem Cell State. Blood. PMID 34499717 DOI: 10.1182/blood.2021010745 |
0.501 |
|
| 2021 |
Herbrich S, Baran N, Cai T, Weng C, Aitken MJL, Post SM, Henderson J, Shi C, Richard-Carpentier G, Sauvageau G, Baggerly K, Al-Atrash G, Davis RE, Daver N, Zha D, et al. Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML. Journal For Immunotherapy of Cancer. 9. PMID 34326171 DOI: 10.1136/jitc-2021-002968 |
0.394 |
|
| 2021 |
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, ... ... Sauvageau G, et al. Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes. Immunity. PMID 33740418 DOI: 10.1016/j.immuni.2021.03.001 |
0.303 |
|
| 2021 |
Chagraoui J, Girard S, Spinella JF, Simon L, Bonneil E, Mayotte N, MacRae T, Coulombe-Huntington J, Bertomeu T, Moison C, Tomellini E, Thibault P, Tyers M, Marinier A, Sauvageau G. UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex. Cell Stem Cell. 28: 48-62.e6. PMID 33417871 DOI: 10.1016/j.stem.2020.12.002 |
0.311 |
|
| 2020 |
Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, ... ... Sauvageau G, et al. UM171-expanded cord blood transplants support robust T cell reconstitution with low rates of severe infections. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 33022376 DOI: 10.1016/j.bbmt.2020.09.031 |
0.334 |
|
| 2020 |
Claveau JS, Cohen S, Ahmad I, Delisle JS, Kiss T, Lachance S, Sauvageau G, Busque L, Brito RM, Bambace N, Bernard L, Claude Roy D, Roy J. Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors. European Journal of Haematology. PMID 32749758 DOI: 10.1111/Ejh.13504 |
0.415 |
|
| 2020 |
Cohen S, Roy J, Lachance S, Roy D, Busque L, Barabé F, Ahmad I, Bambace NM, Bernard L, Kiss TL, Sauvageau G. UM171 Expansion Overcomes Shortcomings of Cord Blood Transplantation While Maintaining Benefits Biology of Blood and Marrow Transplantation. 26: S294-S295. DOI: 10.1016/J.Bbmt.2019.12.571 |
0.42 |
|
| 2020 |
Claveau J, LeBlanc R, Ahmad I, Landais S, Bambace NM, Bernard L, Cohen S, Delisle J, Kiss T, Lachance S, Roy D, Sauvageau G, Roy J. Myeloma Patients Relapsing after First Line Treatment with Tandem Auto/Allo Transplant or Auto Transplant Only Have Similar Outcomes. Biology of Blood and Marrow Transplantation. 26: S228-S229. DOI: 10.1016/J.Bbmt.2019.12.469 |
0.392 |
|
| 2019 |
Kettyle LM, Lebert-Ghali CÉ, Grishagin IV, Dickson GJ, O'Reilly PG, Simpson DA, Bijl JJ, Mills KI, Sauvageau G, Thompson A. Pathways, Processes, and Candidate Drugs Associated with a Cluster-Dependency Model of Leukemia. Cancers. 11. PMID 31861091 DOI: 10.3390/Cancers11122036 |
0.472 |
|
| 2019 |
Cohen S, Roy J, Lachance S, Delisle JS, Marinier A, Busque L, Roy DC, Barabé F, Ahmad I, Bambace N, Bernard L, Kiss T, Bouchard P, Caudrelier P, Landais S, ... ... Sauvageau G, et al. Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study. The Lancet. Haematology. PMID 31704264 DOI: 10.1016/S2352-3026(19)30202-9 |
0.445 |
|
| 2019 |
Chagraoui J, Lehnertz B, Girard S, Spinella JF, Fares I, Tomellini E, Mayotte N, Corneau S, MacRae T, Simon L, Sauvageau G. UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal. Plos One. 14: e0224900. PMID 31703090 DOI: 10.1371/Journal.Pone.0224900 |
0.467 |
|
| 2019 |
Lemieux C, Ahmad I, Bambace NM, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Roy J, Lachance S. Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Lymphoma Patients. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 31521818 DOI: 10.1016/J.Bbmt.2019.09.007 |
0.374 |
|
| 2019 |
Tomellini E, Fares I, Lehnertz B, Chagraoui J, Mayotte N, MacRae T, Bordeleau MÈ, Corneau S, Bisaillon R, Sauvageau G. Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells. Cell Reports. 28: 1063-1073.e5. PMID 31340144 DOI: 10.1016/J.Celrep.2019.06.084 |
0.503 |
|
| 2019 |
Bisaillon R, Moison C, Thiollier C, Krosl J, Bordeleau ME, Lehnertz B, Lavallée VP, MacRae T, Mayotte N, Labelle C, Boucher G, Spinella JF, Boivin I, D'Angelo G, Lavallée S, ... ... Sauvageau G, et al. Genetic characterization of ABT-199 sensitivity in human AML. Leukemia. PMID 31300747 DOI: 10.1038/S41375-019-0485-X |
0.335 |
|
| 2019 |
Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, ... ... Sauvageau G, et al. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia. Cancer Cell. 36: 84-99.e8. PMID 31287994 DOI: 10.1016/J.Ccell.2019.06.003 |
0.36 |
|
| 2019 |
Dubois EL, Guitton-Sert L, Béliveau M, Parmar K, Chagraoui J, Vignard J, Pauty J, Caron MC, Coulombe Y, Buisson R, Jacquet K, Gamblin C, Gao Y, Laprise P, Lebel M, ... Sauvageau G, et al. A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2. Nucleic Acids Research. PMID 31219578 DOI: 10.1093/Nar/Gkz514 |
0.33 |
|
| 2019 |
Angenendt L, Bormann E, Pabst C, Alla V, Görlich D, Braun L, Dohlich K, Schwöppe C, Bohlander SK, Arteaga MF, Wethmar K, Hartmann W, Angenendt A, Kessler T, Mesters RM, ... ... Sauvageau G, et al. The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia. Leukemia. PMID 31182782 DOI: 10.1038/S41375-019-0505-X |
0.45 |
|
| 2019 |
Roy DC, Lachance S, Cohen S, Delisle JS, Kiss T, Sauvageau G, Busque L, Ahmad I, Bernard L, Bambace N, Boumédine RS, Guertin MC, Rezvani K, Mielke S, Perreault C, et al. Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis. British Journal of Haematology. PMID 31135970 DOI: 10.1111/Bjh.15970 |
0.454 |
|
| 2019 |
Garg S, Reyes-Palomares A, He L, Bergeron A, Lavallée VP, Lemieux S, Gendron P, Rohde C, Xia J, Jagdhane P, Müller-Tidow C, Lipka DB, Imren S, Humphries RK, Waskow C, ... ... Sauvageau G, et al. Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML. Blood. PMID 31076446 DOI: 10.1182/Blood.2018862383 |
0.445 |
|
| 2019 |
Moison C, Lavallée VP, Thiollier C, Lehnertz B, Boivin I, Mayotte N, Gareau Y, Fréchette M, Blouin-Chagnon V, Corneau S, Lavallée S, Lemieux S, Marinier A, Hébert J, Sauvageau G. Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition. Blood Advances. 3: 552-563. PMID 30782614 DOI: 10.1182/Bloodadvances.2018028480 |
0.342 |
|
| 2019 |
Lemieux C, Ahmad I, Bambace NM, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Roy J, Lachance S. Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease. Leukemia Research. PMID 30654975 DOI: 10.1016/J.Leukres.2019.01.002 |
0.466 |
|
| 2019 |
Richard-Carpentier G, Marquis M, Beliveau F, Sauvageau G, Hebert J. A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission Blood. 134: 1432-1432. DOI: 10.1182/Blood-2019-129990 |
0.341 |
|
| 2019 |
Cohen S, Roy J, Delisle J, Bambace NM, Ahmad I, Lachance S, Bernard L, Barabe F, Kiss TL, Busque L, Roy D, Milano F, Sauvageau G. UM171 Modified Cord Blood Achieves Excellent Survival and Disease Control after 2 Years of Follow-up in High and Very High Risk Malignancies Blood. 134: 3245-3245. DOI: 10.1182/Blood-2019-121698 |
0.413 |
|
| 2019 |
LeBlanc R, Ahmad I, Terra R, Landais S, Nkoué C, Sebag M, Lemieux-Blanchard É, Bambace N, Bernard L, Cohen S, jean-Sébastien D, Kiss T, Lachance S, Roy D, Sauvageau G, et al. Profound MRD negativity rates after frontline tandem autologous-allogeneic stem cell transplantation followed by bortezomib maintenance in high-risk or young myeloma patients Clinical Lymphoma Myeloma and Leukemia. 19: e41-e42. DOI: 10.1016/J.Clml.2019.09.063 |
0.459 |
|
| 2018 |
Ngom M, Imren S, Maetzig T, Adair JE, Knapp DJHF, Chagraoui J, Fares I, Bordeleau ME, Sauvageau G, Leboulch P, Eaves C, Humphries RK. UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells. Molecular Therapy. Methods & Clinical Development. 10: 156-164. PMID 30101153 DOI: 10.1016/J.Omtm.2018.06.009 |
0.561 |
|
| 2018 |
Marquis M, Beaubois C, Lavallée VP, Abrahamowicz M, Danieli C, Lemieux S, Ahmad I, Wei A, Ting SB, Fleming S, Schwarer A, Grimwade D, Grey W, Hills RK, Vyas P, ... ... Sauvageau G, et al. High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia. Blood Cancer Journal. 8: 68. PMID 30061630 DOI: 10.1038/S41408-018-0103-6 |
0.313 |
|
| 2018 |
Lavallée VP, Chagraoui J, MacRae T, Marquis M, Bonnefoy A, Krosl J, Lemieux S, Marinier A, Pabst C, Rivard GÉ, Hébert J, Sauvageau G. Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin. Leukemia. PMID 29550835 DOI: 10.1038/S41375-018-0069-1 |
0.393 |
|
| 2018 |
Brown FC, Still E, Koche RP, Yim CY, Takao S, Cifani P, Reed C, Gunasekera S, Ficarro SB, Romanienko P, Mark W, McCarthy C, de Stanchina E, Gonen M, Seshan V, ... ... Sauvageau G, et al. MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia. Cancer Discovery. PMID 29431698 DOI: 10.1158/2159-8290.Cd-17-1271 |
0.39 |
|
| 2018 |
Cohen S, Roy J, Lachance S, Marinier A, Barabé F, Delisle J, Roy D, Busque L, Ahmad I, Bambace NM, Bernard L, Kiss T, Caudrelier P, Larochelle F, Bouchard P, ... ... Sauvageau G, et al. Single UM171 Expanded Cord Blood Transplant is Feasible, Safe, and Permits Transplantation of Better HLA Matched Cords with Very Low Transplant Related Mortality Biology of Blood and Marrow Transplantation. 24: S190-S191. DOI: 10.1182/Blood.V130.Suppl_1.658.658 |
0.307 |
|
| 2018 |
Baccelli I, Gareau Y, Lehnertz B, Stephane G, Spinella J, Beautrait A, Corneau S, Mayotte N, Boivin I, Girard S, MacRae T, Frechette M, Leveille K, Krosl J, Thiollier C, ... ... Sauvageau G, et al. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia Blood. 132: 910-910. DOI: 10.1182/Blood-2018-99-114525 |
0.492 |
|
| 2018 |
Richard-Carpentier G, Marquis M, Sauvageau G, Hebert J. High Expression of SPAG1 Is Associated with a Worse Clinical Outcome in Intermediate Risk Acute Myeloid Leukemia That Can be Partially Overcome By Hematopoietic Stem Cell Transplantation Blood. 132: 2804-2804. DOI: 10.1182/Blood-2018-99-113918 |
0.376 |
|
| 2018 |
Leblanc R, Ahmad I, Terra R, Landais S, Nkoue C, Sebag M, Lemieux Blanchard É, Bambace NM, Bernard L, Cohen S, Delisle J, Kiss TL, Lachance S, Roy D, Sauvageau G, et al. Minimal Residual Disease Evaluation Using 8-Color Flow Cytometry Predicts Risk of Relapse in High-Risk and/or Young Myeloma Patients Who Receive Bortezomib Consolidation after Frontline Tandem Transplantation Blood. 132: 4666-4666. DOI: 10.1182/Blood-2018-99-112313 |
0.415 |
|
| 2018 |
Tomellini E, Fares I, Lehnertz B, Chagraoui J, Mayotte N, MacRae T, Corneau S, Sauvageau G. Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells Blood. 132: 1267-1267. DOI: 10.1182/Blood-2018-99-111963 |
0.609 |
|
| 2018 |
Chagraoui J, Tomellini E, Aubert L, Fares I, Spinella J, Girard S, Mayotte N, Roux PP, Sauvageau G. Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion Blood. 132: 2555-2555. DOI: 10.1182/Blood-2018-99-111917 |
0.436 |
|
| 2018 |
Moison C, Lavallee V, Thiollier C, Spinella J, Boivin I, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression Blood. 132: 3925-3925. DOI: 10.1182/Blood-2018-99-111304 |
0.467 |
|
| 2018 |
Simon L, Lavallee V, Bordeleau M, Lehnertz B, MacRae T, Chagraoui J, Spinella J, Boucher G, Bertomeu T, Coulombe-Huntington J, Tyers M, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids Blood. 132: 4675-4675. DOI: 10.1182/Blood-2018-99-111030 |
0.459 |
|
| 2018 |
Cohen S, Roy J, Lachance S, Marinier A, Delisle J, Roy D, Busque L, Ahmad I, Bambace NM, Barabe F, Bernard L, Kiss TL, Bouchard P, Caudrelier P, Larochelle F, ... ... Sauvageau G, et al. Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival Blood. 132: 4658-4658. DOI: 10.1182/Blood-2018-99-110188 |
0.444 |
|
| 2018 |
Bouchard P, Brisebois-Boyer A, Charbonneau-Seguin N, Bonhomme V, Ahmad I, Bernard L, Bambace NM, Cohen S, Delisle J, Kiss TL, Sauvageau G, Roy D, Roy J, Lachance S. Effectiveness of Continuous Infusion of Methylprednisolone for Prevention of Antithymocyte Globulin Infusion-Related Reactions in Preparative Regimens for Allogeneic Hematopoietic Cell Transplantation Biology of Blood and Marrow Transplantation. 24: S331. DOI: 10.1016/J.Bbmt.2017.12.272 |
0.391 |
|
| 2018 |
Boisjoly J, Bouchard P, Ahmad I, Bambace NM, Bernard L, Cohen S, Delisle J, Kiss TL, Roy D, Sauvageau G, Roy J, Lachance S. Pharmacoeconomic Impact and Transplant Outcome Associated to Carmustine (BCNU) Substitution with Bendamustine (Be) in the Conditioning Regimen Prior to Autologous Stem Cell Transplantation for Lymphoma Treatment Biology of Blood and Marrow Transplantation. 24: S131-S132. DOI: 10.1016/J.Bbmt.2017.12.074 |
0.426 |
|
| 2017 |
Simon L, Lavallée VP, Bordeleau ME, Krosl J, Baccelli I, Boucher G, Lehnertz B, Chagraoui J, MacRae T, Ruel R, Chantigny YA, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic landscape of RUNX1-mutated AML reveals importance of RUNX1 allele dosage in genetics and glucocorticoid sensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28855357 DOI: 10.1158/1078-0432.Ccr-17-1259 |
0.308 |
|
| 2017 |
Aucagne R, Girard S, Mayotte N, Lehnertz B, Lopes-Paciencia S, Gendron P, Boucher G, Chagraoui J, Sauvageau G. UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28754713 DOI: 10.1096/Fj.201601219Rrr |
0.39 |
|
| 2017 |
Zhou F, Liu Y, Rohde C, Pauli C, Gerloff D, Köhn M, Misiak D, Bäumer N, Cui C, Göllner S, Oellerich T, Serve H, Garcia-Cuellar MP, Slany R, Maciejewski JP, ... ... Sauvageau G, et al. AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia. Nature Cell Biology. PMID 28650479 DOI: 10.1038/Ncb3563 |
0.421 |
|
| 2017 |
Lemieux S, Sargeant T, Laperrière D, Ismail H, Boucher G, Rozendaal M, Lavallée VP, Ashton-Beaucage D, Wilhelm B, Hébert J, Hilton DJ, Mader S, Sauvageau G. MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets. Nucleic Acids Research. PMID 28472340 DOI: 10.1093/Nar/Gkx338 |
0.31 |
|
| 2017 |
Fares I, Chagraoui J, Lehnertz B, MacRae T, Mayotte N, Tomellini E, Aubert L, Roux PP, Sauvageau G. EPCR expression marks UM171-expanded CD34(+) cord blood stem cells. Blood. PMID 28408459 DOI: 10.1182/Blood-2016-11-750729 |
0.535 |
|
| 2017 |
Priam P, Krasteva V, Rousseau P, D'Angelo G, Gaboury L, Sauvageau G, Lessard JA. SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism. Nature Genetics. PMID 28369034 DOI: 10.1038/Ng.3812 |
0.609 |
|
| 2017 |
Richard-Carpentier G, Sauvageau G. Bringing a Leukemic Stem Cell Gene Signature into Clinics: Are We There Yet? Cell Stem Cell. 20: 300-301. PMID 28257710 DOI: 10.1016/J.Stem.2017.02.010 |
0.478 |
|
| 2017 |
Boisjoly J, Bouchard P, Cohen S, Ahmad I, Bambace NM, Bernard L, Delisle J, Kiss TL, Roy D, Sauvageau G, Roy J, Lachance S. Impact of Carmustine (BCNU) Substitution for Bendamustine in the Conditioning Regimen Prior to Autologous Hematopoietic Cell Transplantation for the Treatment of Lymphoma Blood. 130: 2022-2022. DOI: 10.1182/Blood.V130.Suppl_1.2022.2022 |
0.329 |
|
| 2017 |
Lavallee V, Chagraoui J, Tara M, Marquis M, Arnaud B, Krosl J, Lemieux S, Rivard G, Hébert J, Sauvageau G. Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias Blood. 130: 105-105. DOI: 10.1182/Blood.V130.Suppl_1.105.105 |
0.433 |
|
| 2017 |
Simon L, Lavallée V, Bordeleau M, Krosl J, Baccelli I, Boucher G, Lehnertz B, MacRae T, Ruel R, Lemieux S, Marinier A, Hébert J, Sauvageau G. Abstract 1509: RUNX1 dosage dictates gene signature andin vitroresponse to glucocorticoids in acute myeloid leukemia Cancer Research. 77: 1509-1509. DOI: 10.1158/1538-7445.Am2017-1509 |
0.319 |
|
| 2017 |
Sauvageau G. New strategies for targeting leukemia stem cells Experimental Hematology. 53: S40. DOI: 10.1016/J.Exphem.2017.06.041 |
0.487 |
|
| 2016 |
Baril C, Gavory G, Bidla G, Knævelsrud H, Sauvageau G, Therrien M. Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila. Developmental Biology. PMID 27838340 DOI: 10.1016/J.Ydbio.2016.11.003 |
0.385 |
|
| 2016 |
Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, et al. Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood. PMID 27827829 DOI: 10.1182/Blood-2016-09-740654 |
0.491 |
|
| 2016 |
Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, ... ... Sauvageau G, et al. High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. The Journal of Clinical Investigation. PMID 27797342 DOI: 10.1172/Jci86489 |
0.519 |
|
| 2016 |
Rouette A, Trofimov A, Haberl D, Boucher G, Lavallée VP, D'Angelo G, Hébert J, Sauvageau G, Lemieux S, Perreault C. Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers. Scientific Reports. 6: 34019. PMID 27659694 DOI: 10.1038/Srep34019 |
0.455 |
|
| 2016 |
Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Armstrong RN, Sauvageau G, Hébert J. RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature. Blood. PMID 26968532 DOI: 10.1182/Blood-2016-03-703868 |
0.309 |
|
| 2016 |
Pabst C, Bergeron A, Lavallée VP, Yeh J, Gendron P, Norddahl GL, Krosl J, Boivin I, Deneault E, Simard J, Imren S, Boucher G, Eppert K, Herold T, Bohlander SK, ... ... Sauvageau G, et al. GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo. Blood. PMID 26834243 DOI: 10.1182/Blood-2015-11-683649 |
0.822 |
|
| 2016 |
Lavallée V, Thiollier C, Moison C, Bordeleau M, Boivin I, Boucher G, Gendron P, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1 Blood. 128: 769-769. DOI: 10.1182/Blood.V128.22.769.769 |
0.413 |
|
| 2016 |
Gerby B, Veiga DF, Krosl J, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox P, Chagraoui J, ... ... Sauvageau G, et al. Targeting Pre-Leukemic Stem Cells in T-Acute Lymphoblastic Leukemia Blood. 128: 527-527. DOI: 10.1182/Blood.V128.22.527.527 |
0.514 |
|
| 2016 |
LeBlanc R, Ahmad I, Terra R, Landais S, Sebag M, Lemieux-Blanchard E, Bambace NM, Bernard L, Cohen S, Delisle J, Kiss T, Lachance S, Roy D, Sauvageau G, Roy J. Bortezomib Consolidation after Nonmyeloablative Allogeneic Stem Cell Transplantation Leads to a High Incidence of Immunophenotypic Complete Response in Young and/or High-Risk Multiple Myeloma Patients Blood. 128: 2306-2306. DOI: 10.1182/Blood.V128.22.2306.2306 |
0.354 |
|
| 2016 |
Cardin S, Laramee L, MacRae T, Chagraoui J, Sauvageau G, Humphries RK, Hébert J, Wilhelm BT, Cellot S. Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells Blood. 128: 1535-1535. DOI: 10.1182/Blood.V128.22.1535.1535 |
0.765 |
|
| 2016 |
Lavallée V, Marquis M, Bordeleau M, Chagraoui J, MacRae T, Boivin I, Boucher G, Gendron P, Lemieux S, Bonnefoy A, Rivard GE, Hébert J, Sauvageau G. Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease Blood. 128: 1075-1075. DOI: 10.1182/Blood.V128.22.1075.1075 |
0.416 |
|
| 2015 |
Lebert-Ghali CÉ, Fournier M, Kettyle L, Thompson A, Sauvageau G, Bijl JJ. Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells. Blood. PMID 26585953 DOI: 10.1182/Blood-2015-02-626390 |
0.549 |
|
| 2015 |
Lavallée VP, Baccelli I, Krosl J, Wilhelm B, Barabé F, Gendron P, Boucher G, Lemieux S, Marinier A, Meloche S, Hébert J, Sauvageau G. The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias. Nature Genetics. 47: 1030-7. PMID 26237430 DOI: 10.1038/Ng.3371 |
0.334 |
|
| 2015 |
Fares I, Rivest-Khan L, Cohen S, Sauvageau G. Small molecule regulation of normal and leukemic stem cells. Current Opinion in Hematology. 22: 309-16. PMID 26049751 DOI: 10.1097/Moh.0000000000000151 |
0.557 |
|
| 2015 |
Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9. PMID 25843717 DOI: 10.1016/J.Celrep.2015.03.019 |
0.482 |
|
| 2015 |
Fortier S, MacRae T, Bilodeau M, Sargeant T, Sauvageau G. Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America. 112: 2127-32. PMID 25646475 DOI: 10.1073/Pnas.1418845112 |
0.497 |
|
| 2015 |
Lavallée VP, Gendron P, Lemieux S, D'Angelo G, Hébert J, Sauvageau G. EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations. Blood. 125: 140-3. PMID 25331116 DOI: 10.1182/Blood-2014-07-591529 |
0.352 |
|
| 2015 |
Lavallée V, Gendron P, Boucher G, Lemieux S, Armstrong RN, Boivin I, Sauvageau G, Hébert J. Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements Blood. 126: 802-802. DOI: 10.1182/Blood.V126.23.802.802 |
0.339 |
|
| 2015 |
Adair JE, Haworth KG, Sauvageau G, Heimfeld S, Hocum JD, Trobridge GD, Kiem H. A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy Blood. 126: 4416-4416. DOI: 10.1182/Blood.V126.23.4416.4416 |
0.469 |
|
| 2015 |
Maiga A, Lemieux S, Pabst C, Lavallée V, Bouvier M, Sauvageau G, Hébert J. Transcriptome Analysis Reveals That G Protein-Coupled Receptors Are Potential Diagnostic Markers or Therapeutic Targets in Acute Myeloid Leukemia Blood. 126: 3855-3855. DOI: 10.1182/Blood.V126.23.3855.3855 |
0.428 |
|
| 2015 |
Pabst C, Bergeron A, Lavallée V, Yeh J, Gendron P, Krosl J, Boucher G, Lemieux S, Hébert J, Sauvageau G, Barabé F. The Novel Leukemia Stem Cell Marker GPR56 Discriminates Leukemic Subclones with Divergent Stem Cell Properties in Human Acute Myeloid Leukemia Blood. 126: 1859-1859. DOI: 10.1182/Blood.V126.23.1859.1859 |
0.397 |
|
| 2015 |
Adair JE, Haworth KG, Sauvageau G, Heimfeld S, Kiem H. 79. Development and Validation of a Globally Portable Platform for Lentivirus Mediated Hematopoietic Stem Cell Gene Therapy Molecular Therapy. 23: S34-S35. DOI: 10.1016/S1525-0016(16)33684-X |
0.494 |
|
| 2015 |
Gerby B, Laflamme G, Kwok B, Roux P, Hébert J, Sauvageau G, Hoang T. Targeting pre-leukemic stem cells in T-acute lymphoblastic leukemia Experimental Hematology. 43: S49. DOI: 10.1016/j.exphem.2015.06.066 |
0.345 |
|
| 2015 |
Ahmad I, LeBlanc R, Cohen S, Lachance S, Kiss T, Sauvageau G, Roy D, Busque L, Delisle J, Bambace N, Bernard L, Roy J. Favorable long-term survival of patients with multiple myeloma using a frontline tandem approach with autologous and nonmyeloablative allogeneic transplantation Clinical Lymphoma Myeloma and Leukemia. 15: e133-e134. DOI: 10.1016/J.Clml.2015.07.329 |
0.311 |
|
| 2014 |
Gerby B, Tremblay CS, Tremblay M, Rojas-Sutterlin S, Herblot S, Hébert J, Sauvageau G, Lemieux S, Lécuyer E, Veiga DF, Hoang T. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. Plos Genetics. 10: e1004768. PMID 25522233 DOI: 10.1371/Journal.Pgen.1004768 |
0.489 |
|
| 2014 |
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, ... ... Sauvageau G, et al. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science (New York, N.Y.). 345: 1509-12. PMID 25237102 DOI: 10.1126/Science.1256337 |
0.535 |
|
| 2014 |
Bordeleau ME, Aucagne R, Chagraoui J, Girard S, Mayotte N, Bonneil E, Thibault P, Pabst C, Bergeron A, Barabé F, Hébert J, Sauvageau M, Boutonnet C, Meloche S, Sauvageau G. UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. Blood. 124: 2362-9. PMID 25185265 DOI: 10.1182/Blood-2014-01-548651 |
0.803 |
|
| 2014 |
Pabst C, Krosl J, Fares I, Boucher G, Ruel R, Marinier A, Lemieux S, Hébert J, Sauvageau G. Identification of small molecules that support human leukemia stem cell activity ex vivo. Nature Methods. 11: 436-42. PMID 24562423 DOI: 10.1038/Nmeth.2847 |
0.556 |
|
| 2014 |
Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, et al. The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes & Development. 28: 317-27. PMID 24532712 DOI: 10.1101/Gad.236794.113 |
0.442 |
|
| 2014 |
Celton M, Forest A, Gosse G, Lemieux S, Hebert J, Sauvageau G, Wilhelm BT. Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia. Leukemia. 28: 1617-26. PMID 24514424 DOI: 10.1038/Leu.2014.67 |
0.356 |
|
| 2014 |
Buscarlet M, Krasteva V, Ho L, Simon C, Hébert J, Wilhelm B, Crabtree GR, Sauvageau G, Thibault P, Lessard JA. Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. Blood. 123: 1720-8. PMID 24478402 DOI: 10.1182/Blood-2013-02-483495 |
0.638 |
|
| 2014 |
Fares I, Chagaroui J, Gareau Y, Gingras S, Mayotte N, Csaszar E, Kiem H, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal Blood. 124: 650-650. DOI: 10.1182/Blood.V124.21.650.650 |
0.576 |
|
| 2014 |
Lehnertz B, Boucher G, Mallard W, Gendron P, Hebert J, Lemieux S, Rinn J, Sauvageau G. Long non-coding RNA expression in normal and leukemic human blood samples: Towards the identification of novel biomarkers and hematopoietic regulators Experimental Hematology. 42: S45. DOI: 10.1016/J.Exphem.2014.07.166 |
0.568 |
|
| 2014 |
Buscarlet M, Krasteva V, Ho L, Simon C, Hebert J, Wilhelm B, Crabtree G, Sauvageau G, Thibault P, Lessard J. An exchange of alternative ATPases within BAF complexes accompanies the transition from hemopoietic stem cell quiescence to proliferation Experimental Hematology. 42: S4. DOI: 10.1016/J.Exphem.2014.07.013 |
0.462 |
|
| 2014 |
Sauvageau G. Exploring small molecules to expand human stem cells for transplantation Experimental Hematology. 42: S2. DOI: 10.1016/J.Exphem.2014.07.007 |
0.472 |
|
| 2013 |
Macrae T, Sargeant T, Lemieux S, Hébert J, Deneault E, Sauvageau G. RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells. Plos One. 8: e72884. PMID 24069164 DOI: 10.1371/Journal.Pone.0072884 |
0.742 |
|
| 2013 |
Cellot S, Hope KJ, Chagraoui J, Sauvageau M, Deneault É, MacRae T, Mayotte N, Wilhelm BT, Landry JR, Ting SB, Krosl J, Humphries K, Thompson A, Sauvageau G. RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity. Blood. 122: 1545-55. PMID 23777767 DOI: 10.1182/Blood-2013-04-496281 |
0.821 |
|
| 2013 |
Ramsey JM, Kettyle LM, Sharpe DJ, Mulgrew NM, Dickson GJ, Bijl JJ, Austin P, Mayotte N, Cellot S, Lappin TR, Zhang SD, Mills KI, Krosl J, Sauvageau G, Thompson A. Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia. Stem Cells (Dayton, Ohio). 31: 1434-45. PMID 23592435 DOI: 10.1002/Stem.1398 |
0.701 |
|
| 2013 |
Deneault E, Wilhelm BT, Bergeron A, Barabé F, Sauvageau G. Identification of non-cell-autonomous networks from engineered feeder cells that enhance murine hematopoietic stem cell activity. Experimental Hematology. 41: 470-478.e4. PMID 23340137 DOI: 10.1016/J.Exphem.2013.01.003 |
0.802 |
|
| 2013 |
Holbro A, Ahmad I, Cohen S, Roy J, Lachance S, Chagnon M, LeBlanc R, Bernard L, Busque L, Roy DC, Sauvageau G, Kiss TL. Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 547-51. PMID 23253556 DOI: 10.1016/J.Bbmt.2012.12.006 |
0.331 |
|
| 2013 |
Sauvageau G, Pabst C, Lemieux S, Hébert J, Krosl J. Novel Targeting Strategies for Leukemia-Initiating Cells in Myeloid Neoplasms Blood. 122: SCI-27-SCI-27. DOI: 10.1182/Blood.V122.21.Sci-27.Sci-27 |
0.382 |
|
| 2013 |
Fares I, Chagraoui J, Gareau Y, Gingras S, Rjean R, Csaszar E, Cohen S, Anne M, Zandstra PW, Sauvageau G. UM171 Is a Novel and Potent Agonist Of Human Hematopoietic Stem Cell Renewal Blood. 122: 798-798. DOI: 10.1182/Blood.V122.21.798.798 |
0.502 |
|
| 2013 |
Lavallée V, Gendron P, Boucher G, Arteau M, Wilhelm BT, Lemieux S, Hébert J, Sauvageau G. NGS-Based Detection Of Multiple RAS-Mutated Clones In MLL-Rearranged Leukemias Suggests Strong Oncogenic Collaboration Blood. 122: 744-744. DOI: 10.1182/Blood.V122.21.744.744 |
0.311 |
|
| 2013 |
Bordeleau M, Chagraoui J, Aucagne R, Girard S, Bonneil É, Sauvageau M, Faubert A, Thibault P, Sauvageau G. Ubap2l-Bmi-1-Rnf2 Define a Novel Polycomb Complex Essential For Self-Renewal Of Hematopoietic Stem Cells Blood. 122: 736-736. DOI: 10.1182/Blood.V122.21.736.736 |
0.809 |
|
| 2013 |
Ahmad I, Cohen S, Lachance S, Sauvageau G, Roy D, Busque L, Kiss T, Delisle J, Bernard L, LeBlanc R, Roy J. Pre-Transplant Remission Status and Peripheral Blood Stem Cell Graft Contribute To Long-Term Outcome After Myeloablative Sibling-Donor Allogeneic Transplant For Multiple Myeloma Blood. 122: 5541-5541. DOI: 10.1182/Blood.V122.21.5541.5541 |
0.402 |
|
| 2013 |
Simon C, Chagraoui J, Krosl J, Hebert J, Sauvageau G. Ezh2 Is An Essential Regulator Of T-Cell Development and Oncogenic Transformation Blood. 122: 3729-3729. DOI: 10.1182/Blood.V122.21.3729.3729 |
0.446 |
|
| 2013 |
Ahmad I, Cohen S, Lachance S, Sauvageau G, Kiss T, Busque L, Roy D, Delisle J, Bernard L, LeBlanc R, Roy J. High Progression-Free Survival At 10 Years After Tandem Autologous/Nonmyeloablative Allogeneic Transplants For Multiple Myeloma In a Cohort Of 93 Patients: Impact Of Disease Remission Status At Transplant and Chronic Graft-Versus-Host Disease Blood. 122: 3353-3353. DOI: 10.1182/Blood.V122.21.3353.3353 |
0.355 |
|
| 2013 |
Gori JL, Watts KL, Chandrasekaran D, Sauvageau G, Kiem H. Effective Expansion and Engraftment Of Nonhuman Primate CD34+Hematopoietic Stem Cells After Co-Culture With The Small Molecule UM171 Blood. 122: 1656-1656. DOI: 10.1182/Blood.V122.21.1656.1656 |
0.491 |
|
| 2013 |
Ting S, Lee N, Li M, Russell S, Godde N, Humbert P, Matsuzaki F, Deneault E, Sauvageau G. Perturbation Of Gpsm2/Lgn Enhances Haematopoietic Stem Cell Function Blood. 122: 1176-1176. DOI: 10.1182/Blood.V122.21.1176.1176 |
0.817 |
|
| 2013 |
Fortier S, MacRae T, Sargeant T, Sauvageau G. Regulation of mouse embryonic stem cell fate by ribosomal proteins Experimental Hematology. 41: S29. DOI: 10.1016/J.Exphem.2013.05.116 |
0.534 |
|
| 2013 |
Schmidt E, Chagraoui J, Mayotte N, Krosl J, Pabst C, Sauvageau M, Müller-Tidow C, Sauvageau G. Lats 1 is a putative tumor suppressor in Hoxa9 / Meis induced leukemia Experimental Hematology. 41: S20. DOI: 10.1016/J.Exphem.2013.05.076 |
0.683 |
|
| 2013 |
Grote D, Girard S, Chagraoui J, Yang J, Mayotte N, McRae T, Brown G, Sauvageau G. The Bmi1-interacting protein E4f1 is vital for hematopoietic stem/progenitor cell function Experimental Hematology. 41: S15. DOI: 10.1016/J.Exphem.2013.05.055 |
0.504 |
|
| 2013 |
Guenda K, Roy J, Ahmad I, Bernard L, Cohen S, Delisle J, Kiss T, Roy D, Sauvageau G, Chagnon M, Lachance S. Pneumatosis Coli Associated to Severe Intestinal Graft Versus Host Disease Following Hematopoietic Cell Transplantation: Risk Factors and Dismal Outcome Biology of Blood and Marrow Transplantation. 19: S333. DOI: 10.1016/J.Bbmt.2012.11.506 |
0.359 |
|
| 2013 |
Bambace NM, Poirier L, Cohen S, Kiss T, Sauvageau G, Roy J, Roy D, Chagnon M, Lachance S. Nocardiosis in Allogeneic Hematopoietic Stem Cell Transplant Recipients: A Matched Case-Control Study of Risk Factors, Clinical Features and Outcomes Biology of Blood and Marrow Transplantation. 19: S280. DOI: 10.1016/J.Bbmt.2012.11.396 |
0.354 |
|
| 2013 |
Bourgouin P, Krakow EF, Roy J, Ahmad I, Bernard L, Delisle J, Kiss T, Lachance S, Roy D, Sauvageau G, Cohen S. Prompt Treatment of Respiratory Syncytial Virus with Inhaled Ribavirin and IVIG in High Risk Allogeneic Stem Cell Transplant Recipients Significantly Diminishes Mortality Biology of Blood and Marrow Transplantation. 19: S258-S259. DOI: 10.1016/J.Bbmt.2012.11.347 |
0.411 |
|
| 2012 |
Trost M, Sauvageau M, Hérault O, Deleris P, Pomiès C, Chagraoui J, Mayotte N, Meloche S, Sauvageau G, Thibault P. Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood. 120: e17-27. PMID 22802335 DOI: 10.1182/Blood-2011-12-397844 |
0.805 |
|
| 2012 |
Herault O, Hope KJ, Deneault E, Mayotte N, Chagraoui J, Wilhelm BT, Cellot S, Sauvageau M, Andrade-Navarro MA, Hébert J, Sauvageau G. A role for GPx3 in activity of normal and leukemia stem cells. The Journal of Experimental Medicine. 209: 895-901. PMID 22508837 DOI: 10.1084/Jem.20102386 |
0.843 |
|
| 2012 |
Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux S, Boucher G, Chagnon P, Drouin S, Lambert R, Rondeau C, Bilodeau A, Lavallée S, Sauvageau M, Hébert J, ... Sauvageau G, et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes & Development. 26: 651-6. PMID 22431509 DOI: 10.1101/Gad.186411.111 |
0.743 |
|
| 2012 |
Ting SB, Deneault E, Hope K, Cellot S, Chagraoui J, Mayotte N, Dorn JF, Laverdure JP, Harvey M, Hawkins ED, Russell SM, Maddox PS, Iscove NN, Sauvageau G. Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2. Blood. 119: 2510-22. PMID 22174158 DOI: 10.1182/Blood-2011-11-393272 |
0.863 |
|
| 2012 |
Cohen S, Kiss T, Lachance S, Roy DC, Sauvageau G, Busque L, Ahmad I, Roy J. Tandem autologous-allogeneic nonmyeloablative sibling transplantation in relapsed follicular lymphoma leads to impressive progression-free survival with minimal toxicity. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 18: 951-7. PMID 22155507 DOI: 10.1182/Blood.V114.22.50.50 |
0.359 |
|
| 2012 |
Holbro A, Ahmad I, Busque L, Cohen S, Lachance S, Roy DC, Roy J, Sauvageau G, Kiss T. Cardiac tamponade potentially related to sirolimus following cord blood transplantation. Bone Marrow Transplantation. 47: 294-5. PMID 21399672 DOI: 10.1038/Bmt.2011.44 |
0.359 |
|
| 2012 |
Pécheux L, Ahmad I, Baron C, Busque L, Cohen S, Kiss T, Roy D, Roy J, Sauvageau G, Lachance S. Impact of Graft CD34 Cell Dose on Chronic Graft-Versus-Host Disease (cGVHD) and Predictive Values of CD3 Cell Dose and Day 56 Chimerism on Survival in Nonmyeloablative (Nma) Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Biology of Blood and Marrow Transplantation. 18: S262-S263. DOI: 10.1016/J.Bbmt.2011.12.173 |
0.436 |
|
| 2011 |
Bisaillon R, Wilhelm BT, Krosl J, Sauvageau G. C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein. Blood. 118: 4682-9. PMID 21900201 DOI: 10.1182/Blood-2011-05-354076 |
0.453 |
|
| 2011 |
Ahmad I, Labbé AC, Chagnon M, Busque L, Cohen S, Kiss T, Lachance S, Roy DC, Sauvageau G, Roy J. Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 17: 1673-8. PMID 21601640 DOI: 10.1016/J.Bbmt.2011.04.012 |
0.387 |
|
| 2011 |
Hope KJ, Sauvageau G. Roles for MSI2 and PROX1 in hematopoietic stem cell activity. Current Opinion in Hematology. 18: 203-7. PMID 21577104 DOI: 10.1097/Moh.0B013E328347888A |
0.507 |
|
| 2011 |
Chagraoui J, Hébert J, Girard S, Sauvageau G. An anticlastogenic function for the Polycomb Group gene Bmi1. Proceedings of the National Academy of Sciences of the United States of America. 108: 5284-9. PMID 21402923 DOI: 10.1073/Pnas.1014263108 |
0.388 |
|
| 2011 |
Volpato JP, Mayotte N, Fossati E, Guerrero V, Sauvageau G, Pelletier JN. Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells Journal of Molecular Recognition. 24: 188-198. PMID 21360609 DOI: 10.1002/Jmr.1037 |
0.48 |
|
| 2011 |
Wilhelm BT, Briau M, Austin P, Faubert A, Boucher G, Chagnon P, Hope K, Girard S, Mayotte N, Landry JR, Hébert J, Sauvageau G. RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity. Blood. 117: e27-38. PMID 20980679 DOI: 10.1182/Blood-2010-07-293332 |
0.554 |
|
| 2011 |
Cellot S, Hope KJ, Sauvageau M, Chagraoui J, Deneault E, MacRae T, Mayotte N, Sauvageau G. A Functional In Vivo RNAi screen Involving Jumonji C Domain Containing Candidates Unravels Kdm5b As a Negative Modulator of Hematopoietic Stem Cell Self-Renewal Blood. 118: 385-385. DOI: 10.1182/Blood.V118.21.385.385 |
0.858 |
|
| 2011 |
Pabst C, Hebert J, Sauvageau G. A High-Throughput Screen to Identify Compounds Preserving Primary Human AML Stem Cells Ex-Vivo, Blood. 118: 3587-3587. DOI: 10.1182/Blood.V118.21.3587.3587 |
0.503 |
|
| 2011 |
Roy D, Guerin M, Boumedine RS, Lachance S, Cohen S, Sauvageau G, Kiss T, Busque L, Morin J, Guertin M, Velardi A, Rezvani K, Mielke S, Egeler RM, Barrett AJ, et al. Reduction in Incidence of Severe Infections by Transplantation of High Doses of Haploidentical T Cells Selectively Depleted of Alloreactive Units Blood. 118: 3020-3020. DOI: 10.1182/Blood.V118.21.3020.3020 |
0.43 |
|
| 2011 |
Schmidt E, Krosl J, Chagraoui J, Mayotte N, Pabst C, McRae T, Sauvageau G. Identification of Lats 1 As a Putative Tumor Suppressor in HoxA9/Meis Induced Leukemia Blood. 118: 2474-2474. DOI: 10.1182/Blood.V118.21.2474.2474 |
0.57 |
|
| 2011 |
Fares IH, Chagraoui J, Krosl J, Roy D, Cohen S, Sauvageau G. Screen for Small Molecules Capable of Expanding Human Hematopoietic Stem Cell Ex Vivo Blood. 118: 1919-1919. DOI: 10.1182/Blood.V118.21.1919.1919 |
0.501 |
|
| 2011 |
Deneault E, Wilhelm BT, Barabe F, Sauvageau G. A Novel Osteoclastic Network Determines In Vitro Niche for Mouse and Human Hematopoietic Stem Cells Blood. 118: 1325-1325. DOI: 10.1182/Blood.V118.21.1325.1325 |
0.809 |
|
| 2011 |
Baron C, Ahmad I, Busque L, Cohen S, Depeault L, Lachance S, Roy D, Roy J, Sauvageau G, Kiss T. The Number of CD34+ Cells in Peripheral Blood Pre Leukapheresis of Allogeneic Stem Cell Donors is Related to Donor Demographic and Hematologic Factors on the Day of Collection. Results of a Single Center Stem Cell Collection Validation Study Biology of Blood and Marrow Transplantation. 17: S306. DOI: 10.1016/J.Bbmt.2010.12.455 |
0.53 |
|
| 2010 |
Fortier S, Bilodeau M, Macrae T, Laverdure JP, Azcoitia V, Girard S, Chagraoui J, Ringuette N, Hébert J, Krosl J, Mayotte N, Sauvageau G. Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions. Plos Genetics. 6: e1001241. PMID 21170304 DOI: 10.1371/Journal.Pgen.1001241 |
0.443 |
|
| 2010 |
Sauvageau G, Humphries RK. Medicine. The blood stem cell Holy Grail? Science (New York, N.Y.). 329: 1291-2. PMID 20829472 DOI: 10.1126/Science.1195173 |
0.491 |
|
| 2010 |
Sauvageau M, Sauvageau G. Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell. 7: 299-313. PMID 20804967 DOI: 10.1016/J.Stem.2010.08.002 |
0.799 |
|
| 2010 |
Lebert-Ghali CE, Fournier M, Dickson GJ, Thompson A, Sauvageau G, Bijl JJ. HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells. Experimental Hematology. 38: 1074-1086.e1-5. PMID 20655978 DOI: 10.1016/J.Exphem.2010.07.006 |
0.473 |
|
| 2010 |
Hope KJ, Cellot S, Ting SB, MacRae T, Mayotte N, Iscove NN, Sauvageau G. An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell. 7: 101-13. PMID 20621054 DOI: 10.1016/J.Stem.2010.06.007 |
0.789 |
|
| 2010 |
Krosl J, Mamo A, Chagraoui J, Wilhelm BT, Girard S, Louis I, Lessard J, Perreault C, Sauvageau G. A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations. Blood. 116: 1678-84. PMID 20522713 DOI: 10.1182/Blood-2010-03-273862 |
0.67 |
|
| 2010 |
Lacombe J, Herblot S, Rojas-Sutterlin S, Haman A, Barakat S, Iscove NN, Sauvageau G, Hoang T. Scl regulates the quiescence and the long-term competence of hematopoietic stem cells. Blood. 115: 792-803. PMID 19850742 DOI: 10.1182/Blood-2009-01-201384 |
0.559 |
|
| 2010 |
Ramsey JM, Dickson GJ, Bijl JJ, Mills KI, Lappin TR, Sauvageau G, Thompson A. Differential Gene and MicroRNA Expression In a HOXA9-MEIS1 Model of Leukemia Blood. 116: 64-64. DOI: 10.1182/Blood.V116.21.64.64 |
0.41 |
|
| 2010 |
Herault O, Hope KJ, Deneault E, Trost M, Mayotte N, Chagraoui J, Wilhelm BT, Cellot S, Sauvageau M, Thibault P, Sauvageau G. Gpx3 Determines Competitiveness of Normal and Leukemic Stem Cells. Blood. 116: 1587-1587. DOI: 10.1182/Blood.V116.21.1587.1587 |
0.854 |
|
| 2009 |
Bilodeau M, MacRae T, Gaboury L, Laverdure JP, Hardy MP, Mayotte N, Paradis V, Harton S, Perreault C, Sauvageau G. Analysis of blood stem cell activity and cystatin gene expression in a mouse model presenting a chromosomal deletion encompassing Csta and Stfa2l1. Plos One. 4: e7500. PMID 19838297 DOI: 10.1371/Journal.Pone.0007500 |
0.477 |
|
| 2009 |
Sabry W, Le Blanc R, Labbé AC, Sauvageau G, Couban S, Kiss T, Busque L, Cohen S, Lachance S, Roy DC, Roy J. Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 15: 919-29. PMID 19589481 DOI: 10.1016/J.Bbmt.2009.04.004 |
0.346 |
|
| 2009 |
Deneault E, Cellot S, Faubert A, Laverdure JP, Fréchette M, Chagraoui J, Mayotte N, Sauvageau M, Ting SB, Sauvageau G. A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell. 137: 369-79. PMID 19379700 DOI: 10.1016/J.Cell.2009.03.026 |
0.845 |
|
| 2009 |
Csaszar E, Gavigan G, Ungrin M, Thérien C, Dubé P, Féthière J, Sauvageau G, Roy DC, Zandstra PW. An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures. Biotechnology and Bioengineering. 103: 402-12. PMID 19266473 DOI: 10.1002/Bit.22297 |
0.477 |
|
| 2009 |
Sauvageau G. Manipulating Stem Cells for Therapeutic Expansion. Blood. 114: SCI-42-SCI-42. DOI: 10.1182/Blood.V114.22.Sci-42.Sci-42 |
0.582 |
|
| 2009 |
Krosl J, Lebrun J, Chagraoui J, Lessard J, Mamo A, Sauvageau G. Baf250a Is a Regulator of HSC Populations. Blood. 114: 701-701. DOI: 10.1182/Blood.V114.22.701.701 |
0.697 |
|
| 2009 |
Roy D, Lachance S, Kiss T, Cohen S, Busque L, Fish D, Sauvageau G, Egeler M, Roy J. Haploidentical Stem Cell Transplantation: High Doses of Alloreactive-T Cell Depleted Donor Lymphocytes Administered Post-Transplant Decrease Infections and Improve Survival without Causing Severe Gvhd. Blood. 114: 512-512. DOI: 10.1182/Blood.V114.22.512.512 |
0.45 |
|
| 2009 |
Barakat S, Lambert J, Sauvageau G, Hoang T. ETO2 Controls Hematopoietic Stem Cell Expansion. Blood. 114: 396-396. DOI: 10.1182/Blood.V114.22.396.396 |
0.598 |
|
| 2009 |
Hope KJ, Cellot S, Ting S, Sauvageau G. An RNA Interference Screen Identifies the Cell Fate Determinants Msi2 and Prox1 as Novel Regulators of Hematopoietic Stem Cell Self-Renewal. Blood. 114: 394-394. DOI: 10.1182/Blood.V114.22.394.394 |
0.811 |
|
| 2009 |
Cellot S, Hope KJ, Sauvageau M, Sauvageau G. Histone Demethylases as Modulators of Hematopoietic Cell Fate. Blood. 114: 393-393. DOI: 10.1182/Blood.V114.22.393.393 |
0.862 |
|
| 2009 |
Lachance S, Molucon-Chabrot C, Busque L, Kiss T, Cohen S, Roy D, Roy J, Sauvageau G. First Line Allogeneic Stem Cell Transplantation in Mantle Cell Lymphoma (MCL). Blood. 114: 3366-3366. DOI: 10.1182/Blood.V114.22.3366.3366 |
0.368 |
|
| 2009 |
Ahmad I, Boutin M, Thibault P, Busque L, Cohen S, Kiss T, Lachance S, Roy D, Sauvageau G, Roy J. Collagen and Elastin Degradation Products as Potential Biomarkers for Chronic Graft-Versus-Host Disease (cGVHD). Blood. 114: 1156-1156. DOI: 10.1182/Blood.V114.22.1156.1156 |
0.318 |
|
| 2009 |
Detrait M, Boivin G, Delage R, Béliveau C, Labbé A, Cohen S, Kiss T, Busque L, Roy D, Sauvageau G, Roy J. High Dose Valacyclovir Is Highly Effective to Prevent Cytomegalovirus and Other Herpes Viruses Viremia After Allogeneic Stem Cell Transplantation. Blood. 114: 1140-1140. DOI: 10.1182/Blood.V114.22.1140.1140 |
0.37 |
|
| 2009 |
Roy D, Cohen S, Busque L, Fish D, Kiss T, Lachance S, Sauvageau G, Rovers J, Roy J. Donor Lymphocyte Infusions Depleted of Alloreactive T Cells Decrease Infections without Causing GVHD After Haplotype Mismatched Myeloablative Stem Cell Transplantation Biology of Blood and Marrow Transplantation. 15: 19. DOI: 10.1016/J.Bbmt.2008.12.057 |
0.478 |
|
| 2008 |
Sauvageau G, Perreault C. Killer granzyme B linked to N-myc- and c-myc-dependent HSC survival: isn't that comyc? Cell Stem Cell. 3: 579-80. PMID 19041771 DOI: 10.1016/J.Stem.2008.11.003 |
0.454 |
|
| 2008 |
Faubert A, Chagraoui J, Mayotte N, Fréchette M, Iscove NN, Humphries RK, Sauvageau G. Complementary and independent function for Hoxb4 and Bmi1 in HSC activity. Cold Spring Harbor Symposia On Quantitative Biology. 73: 555-64. PMID 19022763 DOI: 10.1101/sqb.2008.73.030 |
0.427 |
|
| 2008 |
Bijl J, Krosl J, Lebert-Ghali CE, Vacher J, Mayotte N, Sauvageau G. Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia Oncogene. 27: 6356-6364. PMID 18679416 DOI: 10.1038/onc.2008.233 |
0.325 |
|
| 2008 |
Louis I, Heinonen KM, Chagraoui J, Vainio S, Sauvageau G, Perreault C. The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through beta-catenin-independent signaling. Immunity. 29: 57-67. PMID 18617424 DOI: 10.1016/J.Immuni.2008.04.023 |
0.447 |
|
| 2008 |
Sauvageau M, Sauvageau G. Polycomb group genes: keeping stem cell activity in balance. Plos Biology. 6: e113. PMID 18447587 DOI: 10.1371/Journal.Pbio.0060113 |
0.809 |
|
| 2008 |
Sauvageau M, Miller M, Lemieux S, Lessard J, Hébert J, Sauvageau G. Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. Blood. 111: 790-9. PMID 17906077 DOI: 10.1182/Blood-2007-07-098236 |
0.777 |
|
| 2008 |
Ting S, Deneault E, Frechette M, Chagraoui J, Sauvageau G. A Functional Screen Identifies Polarity Genes Implicated in HSC Fate Blood. 112: 732-732. DOI: 10.1182/Blood.V112.11.732.732 |
0.808 |
|
| 2008 |
Therrien M, Laberge G, Koonpaew S, Bidla G, Sauvageau G. Molecular Dissection of Nup98-HoxA9 Oncogenic Activity Using Drosophila Blood. 112: 3785-3785. DOI: 10.1182/Blood.V112.11.3785.3785 |
0.421 |
|
| 2008 |
Sabry W, Fontaine A, Le Blanc R, Sauvageau G, Roy D, Busque L, Cohen S, Kiss T, Lachance S, Roy J. Tandem Autologous-Nonmyeloablative (NMA) Allogeneic(Allo) Transplant (Tx) in Newly Diagnosed Multiple Myeloma (MM) Leads to Improved Survival When Compared to Conventional Allogeneic Transplant Blood. 112: 3299-3299. DOI: 10.1182/Blood.V112.11.3299.3299 |
0.347 |
|
| 2008 |
Chagraoui J, Hebert J, Girard S, Sauvageau G. BMI1 Interacts with FANCD2 at DNA Lesions and Prevents Chromosome Breaks Blood. 112: 3099-3099. DOI: 10.1182/Blood.V112.11.3099.3099 |
0.429 |
|
| 2008 |
Hope KJ, Cellot S, Ting S, Sauvageau G. An RNA Interference Screen Reveals Fate Determinants Implicated in Asymmetric Cell Division as Potential Regulators of Hematopoietic Stem Cell Self-Renewal Blood. 112: 2462-2462. DOI: 10.1182/Blood.V112.11.2462.2462 |
0.799 |
|
| 2008 |
Sabry W, Labbé A, Le Blanc R, Sauvageau G, Roy D, Busque L, Cohen S, Kiss T, Lachance S, Roy J. Graft-Versus-Host Disease (Gvhd) Prophylaxis with Tacrolimus and Mycophenolate Mofetil (MMF) in 131 Matched Sibling Nonmyeloablative (NMA) Transplant Recipients: Long-Term Follow-up Confirms Extremely Low Incidence of Acute (a) Gvhd, High Incidence of Extensive Chronic (c) Gvhd and Favorable Disease Outcome. Blood. 112: 1176-1176. DOI: 10.1182/Blood.V112.11.1176.1176 |
0.329 |
|
| 2007 |
Labbé AC, Su SH, Laverdière M, Pépin J, Patiño C, Cohen S, Kiss T, Lachance S, Sauvageau G, Busque L, Roy DC, Roy J. High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 13: 1192-200. PMID 17889356 DOI: 10.1016/J.Bbmt.2007.06.013 |
0.37 |
|
| 2007 |
Ohta H, Sekulovic S, Bakovic S, Eaves CJ, Pineault N, Gasparetto M, Smith C, Sauvageau G, Humphries RK. Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions. Experimental Hematology. 35: 817-30. PMID 17577930 DOI: 10.1016/J.Exphem.2007.02.012 |
0.773 |
|
| 2007 |
Cellot S, Krosl J, Chagraoui J, Meloche S, Humphries RK, Sauvageau G. Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. Experimental Hematology. 35: 802-16. PMID 17577929 DOI: 10.1016/J.Exphem.2007.02.013 |
0.78 |
|
| 2007 |
Cellot S, Sauvageau G. Zfx: at the crossroads of survival and self-renewal. Cell. 129: 239-41. PMID 17448983 DOI: 10.1016/J.Cell.2007.04.002 |
0.758 |
|
| 2007 |
Bilodeau M, Girard S, Hébert J, Sauvageau G. A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells. Nature Methods. 4: 263-8. PMID 17277782 DOI: 10.1038/Nmeth1011 |
0.45 |
|
| 2007 |
Ting SB, Chagraoui J, Sauvageau G. Differential Expression and Re-Localization of Potential Cell Fate Determinants in Hematopoietic and Leukemia Stem Cells. Blood. 110: 93-93. DOI: 10.1182/Blood.V110.11.93.93 |
0.595 |
|
| 2007 |
Roy D, Cohen S, Busque L, Fish D, Kiss T, Lachance S, Sauvageau G, Caudrelier P, Roy J. Phase I Clinical Trial of Haplotype Mismatched Myeloablative Stem Cell Transplantation: Higher Doses of Donor Lymphocyte Infusions Depleted of Alloreactive Cells Using ATIR May Improve Outcome without Causing GVHD. Blood. 110: 2976-2976. DOI: 10.1182/Blood.V110.11.2976.2976 |
0.452 |
|
| 2007 |
Roy D, Cohen S, Busque L, Fish D, Kiss T, Lachance S, Sauvageau G, Caudrelier P, Roy J. 49: Haplotype mismatched myeloablative stem cell transplantation Biology of Blood and Marrow Transplantation. 13: 20-21. DOI: 10.1016/J.Bbmt.2006.12.052 |
0.503 |
|
| 2006 |
Bilodeau M, Sauvageau G. Uncovering stemness. Nature Cell Biology. 8: 1048-9. PMID 17013416 DOI: 10.1038/ncb1006-1048 |
0.327 |
|
| 2006 |
Chagraoui J, Niessen SL, Lessard J, Girard S, Coulombe P, Sauvageau M, Meloche S, Sauvageau G. E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells. Genes & Development. 20: 2110-20. PMID 16882984 DOI: 10.1101/Gad.1453406 |
0.822 |
|
| 2006 |
Cellot S, Sauvageau G. In vitro stem cell expansion: stepping closer towards self-renewal. Gene Therapy. 13: 1617-8. PMID 16738689 DOI: 10.1038/sj.gt.3302804 |
0.721 |
|
| 2006 |
Mamo A, Krosl J, Kroon E, Bijl J, Thompson A, Mayotte N, Girard S, Bisaillon R, Beslu N, Featherstone M, Sauvageau G. Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation. Blood. 108: 622-9. PMID 16469876 DOI: 10.1182/Blood-2005-06-2244 |
0.357 |
|
| 2006 |
Dhédin N, Chamakhi I, Perreault C, Roy DC, Sauvageau G, Ducruet T, Busque L, Fish D, Bélanger R, Roy J. Evidence that donor intrinsic response to G-CSF is the best predictor of acute graft-vs-host disease following allogeneic peripheral blood stem cell transplantation. Experimental Hematology. 34: 107-14. PMID 16413397 DOI: 10.1016/J.Exphem.2005.09.013 |
0.438 |
|
| 2006 |
Bijl J, Thompson A, Ramirez-Solis R, Krosl J, Grier DG, Lawrence HJ, Sauvageau G. Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. Blood. 108: 116-22. PMID 16339407 DOI: 10.1182/Blood-2005-06-2245 |
0.52 |
|
| 2006 |
Lacombe J, Herblot S, Sauvageau G, Hoang T. SCL and Its Partner E2A Are Required for Long-Term Stem Cell Activity. Blood. 108: 860-860. DOI: 10.1182/Blood.V108.11.860.860 |
0.576 |
|
| 2006 |
Beauchemin S, Krosl G, Beslu N, Krosl J, Sauvageau G, Roy D. Ectopic Expression of Mutated HOXB4 Proteins with Increased Intracellular Stability Affects Both Long and Short Term Hematopoietic Reconstitution. Blood. 108: 3183-3183. DOI: 10.1182/Blood.V108.11.3183.3183 |
0.496 |
|
| 2006 |
Roy D, Cohen S, Busque L, Fish D, Kiss T, Lachance S, Sauvageau G, Caudrelier P, Roy J. Phase I Clinical Study of Donor Lymphocyte Infusion Depleted of Alloreactive T Cells after Haplotype Mismatched Myeloablative Stem Cell Transplantation To Limit Infections and Malignant Relapse without Causing GVHD. Blood. 108: 309-309. DOI: 10.1182/Blood.V108.11.309.309 |
0.442 |
|
| 2006 |
Imren S, Sauvageau G, Eaves CJ, Humphries RK. A NUP98-HOX Fusion Gene Containing the Homeodomain of HOXA10 Promotes Significant Expansion of Primitive Human Hematopoietic Cells in Extended Cultures. Blood. 108: 1351-1351. DOI: 10.1182/Blood.V108.11.1351.1351 |
0.488 |
|
| 2005 |
Lawrence HJ, Christensen J, Fong S, Hu YL, Weissman I, Sauvageau G, Humphries RK, Largman C. Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood. 106: 3988-94. PMID 16091451 DOI: 10.1182/Blood-2005-05-2003 |
0.616 |
|
| 2005 |
Martin NL, Saba-El-Leil MK, Sadekova S, Meloche S, Sauvageau G. EN2 is a candidate oncogene in human breast cancer. Oncogene. 24: 6890-901. PMID 16007149 DOI: 10.1038/Sj.Onc.1208840 |
0.355 |
|
| 2005 |
Cellot S, Sauvageau G. Gfi-1: another piece in the HSC puzzle. Trends in Immunology. 26: 68-71. PMID 15668120 DOI: 10.1016/J.It.2004.12.005 |
0.769 |
|
| 2005 |
Bijl J, Sauvageau M, Thompson A, Sauvageau G. High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia. Genes & Development. 19: 224-33. PMID 15655112 DOI: 10.1101/Gad.1268505 |
0.754 |
|
| 2005 |
Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, Osato M, Ito Y, Kroon E, Sauvageau G, Nakamura T. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood. 105: 784-93. PMID 15454493 DOI: 10.1182/Blood-2004-04-1508 |
0.43 |
|
| 2005 |
Cellot S, Krosl J, Humphries K, Sauvageau G. Deterministic Trigger of Self-Renewal in Expanded HSCs Expressing Hoxb4 + Antisense Pbx1. Blood. 106: 800-800. DOI: 10.1182/Blood.V106.11.800.800 |
0.858 |
|
| 2005 |
Krosl G, Giard M, Krosl J, Beauchemin S, Humphries K, Sauvageau G, Roy DC. Ex Vivo Expansion of Human SCID-Repopulating Cells Using Recombinant TAT-HOXB4 Protein. Blood. 106: 3159-3159. DOI: 10.1182/Blood.V106.11.3159.3159 |
0.795 |
|
| 2005 |
Rioux-Masse B, Roy J, Belanger R, Roy D, Busque L, Fish D, Sauvageau G, Kiss T, Cohen S. Autologous Bone Marrow Transplant after Failed Peripheral Blood Stem Cell Mobilization Does Not Adversely Affect Engraftment or Transplant Related Toxicity. Blood. 106: 2736-2736. DOI: 10.1182/Blood.V106.11.2736.2736 |
0.424 |
|
| 2005 |
Sauvageau M, Sauvageau G. Defining Candidate Oncogenes Leading to Increased Susceptibility to Leukemia in eed Mutant Mice. Blood. 106: 2622-2622. DOI: 10.1182/Blood.V106.11.2622.2622 |
0.737 |
|
| 2005 |
Lacombe J, Krosl G, Herblot S, Martin R, Aplan PD, Begley C, Sauvageau G, Hoang T. Genetic Interaction between SCL and c-Kit in Hematopoietic Cell Survival. Blood. 106: 2268-2268. DOI: 10.1182/Blood.V106.11.2268.2268 |
0.471 |
|
| 2005 |
Krosl G, Giard M, Krosl J, Humphries R, Sauvageau G, Roy D. Human hematopoietic stem cells can be expanded ex vivo using recombinant TAT-HOXB4 protein Biology of Blood and Marrow Transplantation. 11: 19. DOI: 10.1016/J.Bbmt.2004.12.054 |
0.513 |
|
| 2004 |
Faubert A, Lessard J, Sauvageau G. Are genetic determinants of asymmetric stem cell division active in hematopoietic stem cells? Oncogene. 23: 7247-55. PMID 15378084 DOI: 10.1038/Sj.Onc.1207944 |
0.684 |
|
| 2004 |
Sauvageau G, Iscove NN, Humphries RK. In vitro and in vivo expansion of hematopoietic stem cells. Oncogene. 23: 7223-32. PMID 15378082 DOI: 10.1038/Sj.Onc.1207942 |
0.528 |
|
| 2004 |
Lessard J, Faubert A, Sauvageau G. Genetic programs regulating HSC specification, maintenance and expansion. Oncogene. 23: 7199-209. PMID 15378080 DOI: 10.1038/Sj.Onc.1207940 |
0.683 |
|
| 2004 |
Beslu N, Krosl J, Laurin M, Mayotte N, Humphries KR, Sauvageau G. Molecular interactions involved in HOXB4-induced activation of HSC self-renewal. Blood. 104: 2307-14. PMID 15226173 DOI: 10.1182/Blood-2004-04-1653 |
0.765 |
|
| 2004 |
Krosl JK, Faubert A, Sauvageau G. Molecular basis for stem-cell self-renewal. The Hematology Journal : the Official Journal of the European Haematology Association / Eha. 5: S118-21. PMID 15190292 DOI: 10.1038/Sj.Thj.6200436 |
0.493 |
|
| 2004 |
Chagraoui J, Niessen S, Lessard J, Girard S, Coulombe P, Meloche S, Sauvageau G. p120E4F-1: A Novel Candidate Factor for Mediating Bmi-1 Function in Hematopoietic Stem Cells. Blood. 104: 370-370. DOI: 10.1182/Blood.V104.11.370.370 |
0.66 |
|
| 2004 |
Cellot S, Krosl J, Humphries K, Sauvageau G. Revealing the Interplay of Extrinsic Versus Intrinsic Regulators of Self-Renewal in Hoxb4-Transduced HSCs. Blood. 104: 367-367. DOI: 10.1182/Blood.V104.11.367.367 |
0.853 |
|
| 2004 |
Bilodeau M, Sauvageau G. A Search for Genes Specifying HSCs through the Development of a New Retroviral-Based System That Creates Nested Deletions in ES cells. Blood. 104: 3223-3223. DOI: 10.1182/Blood.V104.11.3223.3223 |
0.405 |
|
| 2004 |
Krosl G, Giard M, Krosl J, Humphries RK, Sauvageau G, Roy D. Recombinant TAT-HOXB4 Protein Promotes Ex Vivo Expansion of Primitive Human Hematopoietic Cells. Blood. 104: 2855-2855. DOI: 10.1182/Blood.V104.11.2855.2855 |
0.483 |
|
| 2004 |
Sauvageau M, Post-Doc JL, Miller M, Sauvageau G. Identification of Oncogenic Collaborators Providing Insights into the Tumor Suppressing Function of the Eed Polycomb Group (PcG) Gene. Blood. 104: 213-213. DOI: 10.1182/Blood.V104.11.213.213 |
0.731 |
|
| 2004 |
Ohta H, Bakovic S, Pineault N, Sauvageau G, Humphries RK. Multi-Log Clonal Ex-Vivo Expansion of Long Term Lympho-Myeloid Hematopoietic Stem Cells by Nup98-Hox Fusion Genes. Blood. 104: 153-153. DOI: 10.1182/Blood.V104.11.153.153 |
0.567 |
|
| 2004 |
Bijl JJ, Sauvageau M, Thompson A, Sauvageau G. The Hox a Locus Is Strongly Targeted by MMLV in an E2a-PBX1 Induced B-Cell Leukemia Model. Blood. 104: 1529-1529. DOI: 10.1182/Blood.V104.11.1529.1529 |
0.695 |
|
| 2003 |
Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G. In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nature Medicine. 9: 1428-32. PMID 14578881 DOI: 10.1038/Nm951 |
0.553 |
|
| 2003 |
Lessard J, Sauvageau G. Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis. Experimental Hematology. 31: 567-85. PMID 12842702 DOI: 10.1016/S0301-472X(03)00081-X |
0.662 |
|
| 2003 |
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature. 423: 255-60. PMID 12714970 DOI: 10.1038/Nature01572 |
0.73 |
|
| 2003 |
Krosl J, Beslu N, Mayotte N, Humphries RK, Sauvageau G. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity. 18: 561-71. PMID 12705858 DOI: 10.1016/S1074-7613(03)00090-6 |
0.578 |
|
| 2002 |
Mayotte N, Roy DC, Yao J, Kroon E, Sauvageau G. Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system. Blood. 100: 4177-84. PMID 12393433 DOI: 10.1182/Blood-2002-04-1244 |
0.466 |
|
| 2002 |
Buske C, Feuring-Buske M, Abramovich C, Spiekermann K, Eaves CJ, Coulombel L, Sauvageau G, Hogge DE, Humphries RK. Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood. 100: 862-8. PMID 12130496 DOI: 10.1182/Blood-2002-01-0220 |
0.595 |
|
| 2002 |
Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 109: 39-45. PMID 11955445 DOI: 10.1016/S0092-8674(02)00697-9 |
0.86 |
|
| 2002 |
Thorsteinsdottir U, Mamo A, Kroon E, Jerome L, Bijl J, Lawrence HJ, Humphries K, Sauvageau G. Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood. 99: 121-9. PMID 11756161 DOI: 10.1182/Blood.V99.1.121 |
0.811 |
|
| 2001 |
Antonchuk J, Sauvageau G, Humphries RK. HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation Experimental Hematology. 29: 1125-1134. PMID 11532354 DOI: 10.1016/S0301-472X(01)00681-6 |
0.59 |
|
| 2001 |
Kroon E, Thorsteinsdottir U, Mayotte N, Nakamura T, Sauvageau G. NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice Embo Journal. 20: 350-361. PMID 11157742 DOI: 10.1093/Emboj/20.3.350 |
0.488 |
|
| 2001 |
Thorsteinsdottir U, Kroon E, Jerome L, Blasi F, Sauvageau G. Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia Molecular and Cellular Biology. 21: 224-234. PMID 11113197 DOI: 10.1128/Mcb.21.1.224-234.2001 |
0.364 |
|
| 2000 |
Krosl J, Sauvageau G. AP-1 complex is effector of Hox-induced cellular proliferation and transformation Oncogene. 19: 5134-5141. PMID 11064450 DOI: 10.1038/Sj.Onc.1203897 |
0.398 |
|
| 2000 |
Thorsteinsdottir U, Jerome L, Kroon E, Sauvageau G. Evidence for a mitotic clock in HSC which impairs hoxa9-induced leukemic transformation Blood. 96. |
0.393 |
|
| 1999 |
Lessard J, Schumacher A, Thorsteinsdottir U, van Lohuizen M, Magnuson T, Sauvageau G. Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation. Genes & Development. 13: 2691-703. PMID 10541555 DOI: 10.1101/Gad.13.20.2691 |
0.685 |
|
| 1999 |
Thorsteinsdottir U, Sauvageau G, Humphries RK. Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size Blood. 94: 2605-2612. PMID 10515864 DOI: 10.1182/Blood.V94.8.2605.420K19_2605_2612 |
0.571 |
|
| 1999 |
Thorsteinsdottir U, Krosl J, Kroon E, Haman A, Hoang T, Sauvageau G. The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells Molecular and Cellular Biology. 19: 6355-6366. PMID 10454582 DOI: 10.1128/Mcb.19.9.6355 |
0.439 |
|
| 1998 |
Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b Embo Journal. 17: 3714-3725. PMID 9649441 DOI: 10.1093/Emboj/17.13.3714 |
0.453 |
|
| 1998 |
Lessard J, Baban S, Sauvageau G. Stage-specific expression of polycomb group genes in human bone marrow cells. Blood. 91: 1216-24. PMID 9454751 DOI: 10.1182/Blood.V91.4.1216 |
0.655 |
|
| 1998 |
Sauvageau G. Developmental genes and hemopo1etic stem cells Experimental Hematology. 26: 682. |
0.455 |
|
| 1997 |
Thorsteinsdottir U, Sauvageau G, Humphries RK. Hox homeobox genes as regulators of normal and leukemic hematopoiesis Hematology/Oncology Clinics of North America. 11: 1221-1237. PMID 9443054 DOI: 10.1016/S0889-8588(05)70491-3 |
0.559 |
|
| 1997 |
Lawrence HJ, Helgason CD, Sauvageau G, Fong S, Izon DJ, Humphries RK, Largman C. Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis Blood. 89: 1922-1930. PMID 9058712 DOI: 10.1182/Blood.V89.6.1922 |
0.51 |
|
| 1997 |
Sauvageau G, Thorsteinsdottir U, Hough MR, Hugo P, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation Immunity. 6: 13-22. PMID 9052833 DOI: 10.1016/S1074-7613(00)80238-1 |
0.367 |
|
| 1997 |
Thorsteinsdottir U, Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ, Largman C, Keith Humphries R. Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia Molecular and Cellular Biology. 17: 495-505. PMID 8972230 DOI: 10.1128/Mcb.17.1.495 |
0.538 |
|
| 1997 |
Sauvageau G, Humphries RK. Expression and function of Hox genes in normal and leukemic hematopoiesis Hematologie. 3: 123-131. |
0.388 |
|
| 1997 |
Lessard J, Baban S, Sauvageau G. Polycomb group genes are differentially expressed in hemopoietic subpopulations Experimental Hematology. 25: 794. |
0.604 |
|
| 1996 |
Lawrence HJ, Sauvageau G, Humphries RK, Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis Stem Cells. 14: 281-291. PMID 8724694 DOI: 10.1002/Stem.140281 |
0.566 |
|
| 1996 |
Helgason CD, Sauvageau G, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro Blood. 87: 2740-2749. PMID 8639890 |
0.503 |
|
| 1995 |
Sauvageau G, Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Lansdorp PM, Humphries RK. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo Genes and Development. 9: 1753-1765. PMID 7622039 DOI: 10.1101/Gad.9.14.1753 |
0.618 |
|
| 1995 |
Lawrence HJ, Sauvageau G, Ahmadi N, Lopez AR, LeBeau MM, Link M, Humphries K, Largman C. Stage- and lineage-specific expression of the HOXA10 homeohox gene in normal and leukemic hematopoietic cells Experimental Hematology. 23: 1160-1166. PMID 7556525 |
0.364 |
|
| 1994 |
Sauvageau G, Lansdorp PM, Eaves CJ, Hogge DE, Dragowska WH, Reid DS, Largman C, Lawrence HJ, Humphries RK. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells Proceedings of the National Academy of Sciences of the United States of America. 91: 12223-12227. PMID 7527557 DOI: 10.1073/Pnas.91.25.12223 |
0.507 |
|
| 1990 |
Sauvageau G, Stocco R, Kasparian S, Menezes J. Epstein-Barr virus receptor expression on human CD8+ (cytotoxic/suppressor) T lymphocytes Journal of General Virology. 71: 379-386. PMID 2155291 DOI: 10.1099/0022-1317-71-2-379 |
0.355 |
|
| 1988 |
Stocco R, Sauvageau G, Menezes J. Differences in Epstein-Barr virus (EBV) receptors expression on various human lymphoid targets and their significance to EBV-cell interaction Virus Research. 11: 209-225. PMID 2848382 DOI: 10.1016/0168-1702(88)90084-6 |
0.384 |
|
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