Nicole M. Ashpole, Ph.D. - Publications

Affiliations: 
2012 Neuroscience Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Neuroscience Biology, Genetics, General Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Prabhu D, Khan S, Blackburn K, Posey J, Ashpole NM. Loss of Insulin-like Growth Factor-1 Signaling in Astrocytes Disrupts Glutamate Handling. Journal of Neurochemistry. PMID 31563149 DOI: 10.1111/Jnc.14879  0.401
2017 Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Springo Z, Fulop GA, Ashpole N, Gautam T, Giles CB, Wren JD, Sonntag WE, Csiszar A, Ungvari Z. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. PMID 28295976 DOI: 10.1111/Acel.12583  0.304
2016 Zhang D, Marlin MC, Liang Z, Ahmad M, Ashpole N, Sonntag W, Zhao ZJ, Li G. Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A. The Journal of Biological Chemistry. PMID 27655914 DOI: 10.1074/Jbc.M116.728550  0.356
2016 Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordrecht, Netherlands). PMID 27613724 DOI: 10.1007/S11357-016-9931-0  0.309
2015 Toth P, Tarantini S, Ashpole NM, Tucsek Z, Milne GL, Valcarcel-Ares NM, Menyhart A, Farkas E, Sonntag WE, Csiszar A, Ungvari Z. IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. PMID 26172407 DOI: 10.1111/Acel.12372  0.303
2015 Lee WH, Xu Z, Ashpole NM, Hudmon A, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG. Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics. Neuropharmacology. PMID 26071110 DOI: 10.1016/J.Neuropharm.2015.05.038  0.63
2014 Toth P, Tarantini S, Tucsek Z, Ashpole NM, Sosnowska D, Gautam T, Ballabh P, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. American Journal of Physiology. Heart and Circulatory Physiology. 306: H299-308. PMID 24322615 DOI: 10.1152/Ajpheart.00744.2013  0.327
2013 Ashpole NM, Chawla AR, Martin MP, Brustovetsky T, Brustovetsky N, Hudmon A. Loss of calcium/calmodulin-dependent protein kinase II activity in cortical astrocytes decreases glutamate uptake and induces neurotoxic release of ATP. The Journal of Biological Chemistry. 288: 14599-611. PMID 23543737 DOI: 10.1074/Jbc.M113.466235  0.687
2012 Song W, Xiao Y, Chen H, Ashpole NM, Piekarz AD, Ma P, Hudmon A, Cummins TR, Shou W. The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity. The Journal of Physiology. 590: 5123-39. PMID 22826127 DOI: 10.1113/Jphysiol.2012.235374  0.627
2012 Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A. Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites. The Journal of Biological Chemistry. 287: 19856-69. PMID 22514276 DOI: 10.1074/Jbc.M111.322537  0.637
2012 Ashpole NM, Song W, Brustovetsky T, Engleman EA, Brustovetsky N, Cummins TR, Hudmon A. Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. The Journal of Biological Chemistry. 287: 8495-506. PMID 22253441 DOI: 10.1074/Jbc.M111.323915  0.697
2012 Ashpole NM, Song W, Brustovetsky T, Brustovetsky N, Hudmon A. CaMKII Regulation of Calcium Homeostasis and Neuronal Activity Biophysical Journal. 102: 509a. DOI: 10.1016/J.Bpj.2011.11.2789  0.68
2012 Johnson DE, Kaiser DJ, Ashpole NM, Hudmon A. Structural and Catalytic Mechanisms Underlying CaMKII Substrate Selection Biophysical Journal. 102: 271a. DOI: 10.1016/J.Bpj.2011.11.1494  0.641
2011 Brittain JM, Chen L, Wilson SM, Brustovetsky T, Gao X, Ashpole NM, Molosh AI, You H, Hudmon A, Shekhar A, White FA, Zamponi GW, Brustovetsky N, Chen J, Khanna R. Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2). The Journal of Biological Chemistry. 286: 37778-92. PMID 21832084 DOI: 10.1074/Jbc.M111.255455  0.667
2011 Coultrap SJ, Vest RS, Ashpole NM, Hudmon A, Bayer KU. CaMKII in cerebral ischemia. Acta Pharmacologica Sinica. 32: 861-72. PMID 21685929 DOI: 10.1038/Aps.2011.68  0.679
2011 Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, ... ... Ashpole NM, et al. Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. Nature Medicine. 17: 822-9. PMID 21642979 DOI: 10.1038/Nm.2345  0.652
2011 Li L, Khanna M, Jo I, Wang F, Ashpole NM, Hudmon A, Meroueh SO. Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferation. Journal of Chemical Information and Modeling. 51: 755-9. PMID 21438548 DOI: 10.1021/Ci100490W  0.612
2011 Ashpole NM, Hudmon A. Excitotoxic neuroprotection and vulnerability with CaMKII inhibition. Molecular and Cellular Neurosciences. 46: 720-30. PMID 21316454 DOI: 10.1016/J.Mcn.2011.02.003  0.691
2011 Ashpole NM, Johnson DE, Hudmon A. Molecular Mechanism of Alpha-CaMKII Self-Association Biophysical Journal. 100: 85a-86a. DOI: 10.1016/J.Bpj.2010.12.672  0.61
2011 Herren AW, Ashpole NM, Ginsburg KS, Bers DM, Hudmon A. CaMKII Regulates Cardiac Sodium Channel Nav1.5 by Phosphorylation in the Loop Between Domain I and II Biophysical Journal. 100: 421a. DOI: 10.1016/J.Bpj.2010.12.2491  0.653
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