Year |
Citation |
Score |
2023 |
Kumar S, Budhathoki S, Oliveira CB, Kahle AD, Calhan OY, Lukens JR, Deppmann CD. Role of the Caspase-8/RIPK3 axis in Alzheimer's disease pathogenesis and Aβ-induced NLRP3 inflammasome activation. Jci Insight. PMID 36602874 DOI: 10.1172/jci.insight.157433 |
0.76 |
|
2022 |
Zengeler KE, Shapiro DA, Bruch KR, Lammert CR, Ennerfelt H, Lukens JR. SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology. Brain, Behavior, and Immunity. PMID 36343752 DOI: 10.1016/j.bbi.2022.10.024 |
0.767 |
|
2022 |
Ennerfelt H, Frost EL, Shapiro DA, Holliday C, Zengeler KE, Voithofer G, Bolte AC, Lammert CR, Kulas JA, Ulland TK, Lukens JR. SYK coordinates neuroprotective microglial responses in neurodegenerative disease. Cell. PMID 36257314 DOI: 10.1016/j.cell.2022.09.030 |
0.768 |
|
2020 |
Bolte AC, Dutta AB, Hurt ME, Smirnov I, Kovacs MA, McKee CA, Ennerfelt HE, Shapiro D, Nguyen BH, Frost EL, Lammert CR, Kipnis J, Lukens JR. Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nature Communications. 11: 4524. PMID 32913280 DOI: 10.1038/S41467-020-18113-4 |
0.739 |
|
2020 |
Batista SJ, Still KM, Johanson D, Thompson JA, OʼBrien CA, Lukens JR, Harris TH. Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection. Nature Communications. 11: 3687. PMID 32703941 DOI: 10.1038/S41467-020-17491-Z |
0.343 |
|
2020 |
Ennerfelt HE, Lukens JR. The role of innate immunity in Alzheimer's disease. Immunological Reviews. PMID 32588460 DOI: 10.1111/Imr.12896 |
0.349 |
|
2020 |
Lukens JR, Anand PK. Adapt(ed) to repair - T2 immune responses in the bladder promote recurrent infections. Nature Immunology. PMID 32424364 DOI: 10.1038/S41590-020-0689-2 |
0.327 |
|
2020 |
Lammert CR, Frost EL, Bellinger CE, Bolte AC, McKee CA, Hurt ME, Paysour MJ, Ennerfelt HE, Lukens JR. AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment. Nature. 580: 647-652. PMID 32350463 DOI: 10.1038/S41586-020-2174-3 |
0.767 |
|
2020 |
Su Z, Frost EL, Lammert CR, Przanowska RK, Lukens JR, Dutta A. tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model. Rna Biology. PMID 31983265 DOI: 10.1080/15476286.2020.1721047 |
0.758 |
|
2019 |
Kumar S, Lukens JR. NLRP3 sets the table for a parasitic meal. Journal of Leukocyte Biology. PMID 31063612 DOI: 10.1002/Jlb.4Ce0319-088R |
0.701 |
|
2019 |
Paysour MJ, Bolte AC, Lukens JR. Crosstalk Between the Microbiome and Gestational Immunity in Autism-Related Disorders. Dna and Cell Biology. PMID 30817175 DOI: 10.1089/Dna.2019.4653 |
0.374 |
|
2019 |
Lammert CR, Lukens JR. Modeling Autism-Related Disorders in Mice with Maternal Immune Activation (MIA). Methods in Molecular Biology (Clifton, N.J.). 1960: 227-236. PMID 30798536 DOI: 10.1007/978-1-4939-9167-9_20 |
0.764 |
|
2019 |
Ruhl D, Du TT, Wagner EL, Hwan Choi J, Li S, Reed R, Kim K, Freeman M, Hashisaki G, Lukens JR, Shin JB. Necroptosis and apoptosis contribute to cisplatin and aminoglycoside ototoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30733218 DOI: 10.1523/Jneurosci.1384-18.2019 |
0.302 |
|
2019 |
Kumar S, Budhathoki S, Oliveira C, Lukens J, Deppmann C. P2-195: ROLE OF EXTRINSIC APOPTOSIS AND NECROPTOSIS IN ALZHEIMER'S DISEASE PATHOGENESIS Alzheimer's & Dementia. 15: P651-P651. DOI: 10.1016/J.Jalz.2019.06.2602 |
0.736 |
|
2018 |
Louveau A, Herz J, Alme MN, Salvador AF, Dong MQ, Viar KE, Herod SG, Knopp J, Setliff JC, Lupi AL, Da Mesquita S, Frost EL, Gaultier A, Harris TH, Cao R, ... ... Lukens JR, et al. CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. Nature Neuroscience. PMID 30224810 DOI: 10.1038/S41593-018-0227-9 |
0.407 |
|
2018 |
Bolte AC, Lukens JR. Th17 Cells in Parkinson's Disease: The Bane of the Midbrain. Cell Stem Cell. 23: 5-6. PMID 29979991 DOI: 10.1016/J.Stem.2018.06.016 |
0.323 |
|
2018 |
Lammert CR, Frost EL, Bolte AC, Paysour MJ, Shaw ME, Bellinger CE, Weigel TK, Zunder ER, Lukens JR. Cutting Edge: Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism. Journal of Immunology (Baltimore, Md. : 1950). PMID 29967099 DOI: 10.4049/Jimmunol.1701755 |
0.773 |
|
2017 |
Gharagozloo M, Gris KV, Mahvelati T, Amrani A, Lukens JR, Gris D. NLR-Dependent Regulation of Inflammation in Multiple Sclerosis- Dependent Regulation of Inflammation in Multiple Sclerosis. Frontiers in Immunology. 8: 2012. PMID 29403486 DOI: 10.3389/Fimmu.2017.02012 |
0.382 |
|
2017 |
Gurung P, Fan G, Lukens JR, Vogel P, Tonks NK, Kanneganti TD. Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity. PMID 28410990 DOI: 10.1016/J.Immuni.2017.03.014 |
0.322 |
|
2017 |
Rhoads JP, Lukens JR, Wilhelm AJ, Moore JL, Mendez-Fernandez Y, Kanneganti TD, Major AS. Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9. Journal of Immunology (Baltimore, Md. : 1950). PMID 28130494 DOI: 10.4049/Jimmunol.1601563 |
0.324 |
|
2016 |
McKee CA, Lukens JR. Emerging Roles for the Immune System in Traumatic Brain Injury. Frontiers in Immunology. 7: 556. PMID 27994591 DOI: 10.3389/Fimmu.2016.00556 |
0.37 |
|
2016 |
Frost EL, Lukens JR. The brain's reward circuitry regulates immunity. Nature Medicine. 22: 835-7. PMID 27490435 DOI: 10.1038/Nm.4157 |
0.329 |
|
2015 |
Gadani SP, Walsh JT, Lukens JR, Kipnis J. Dealing with Danger in the CNS: The Response of the Immune System to Injury. Neuron. 87: 47-62. PMID 26139369 DOI: 10.1016/J.Neuron.2015.05.019 |
0.369 |
|
2015 |
Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD. The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells. Immunity. 42: 654-64. PMID 25888258 DOI: 10.1016/J.Immuni.2015.03.006 |
0.439 |
|
2015 |
Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani S, Hechler D, Gölz G, Rosenberger K, Kammertöns T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, et al. MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. The Journal of Clinical Investigation. 125: 699-714. PMID 25607842 DOI: 10.1172/Jci76210 |
0.396 |
|
2015 |
Gurung P, Lukens JR, Kanneganti TD. Mitochondria: diversity in the regulation of the NLRP3 inflammasome. Trends in Molecular Medicine. 21: 193-201. PMID 25500014 DOI: 10.1016/J.Molmed.2014.11.008 |
0.355 |
|
2014 |
Lukens JR, Gurung P, Vogel P, Johnson GR, Carter RA, McGoldrick DJ, Bandi SR, Calabrese CR, Vande Walle L, Lamkanfi M, Kanneganti TD. Dietary modulation of the microbiome affects autoinflammatory disease. Nature. 516: 246-9. PMID 25274309 DOI: 10.1038/Nature13788 |
0.335 |
|
2014 |
Lukens JR, Kanneganti TD. Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease. Seminars in Immunopathology. 36: 595-609. PMID 24838628 DOI: 10.1007/S00281-014-0434-8 |
0.357 |
|
2014 |
Lukens JR, Gross JM, Calabrese C, Iwakura Y, Lamkanfi M, Vogel P, Kanneganti TD. Critical role for inflammasome-independent IL-1β production in osteomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 111: 1066-71. PMID 24395792 DOI: 10.1073/Pnas.1318688111 |
0.322 |
|
2013 |
Weinlich R, Oberst A, Dillon CP, Janke LJ, Milasta S, Lukens JR, Rodriguez DA, Gurung P, Savage C, Kanneganti TD, Green DR. Protective roles for caspase-8 and cFLIP in adult homeostasis. Cell Reports. 5: 340-8. PMID 24095739 DOI: 10.1016/J.Celrep.2013.08.045 |
0.312 |
|
2013 |
Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD. RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3. Nature. 498: 224-7. PMID 23708968 DOI: 10.1038/Nature12174 |
0.348 |
|
2012 |
Lukens JR, Gross JM, Kanneganti TD. IL-1 family cytokines trigger sterile inflammatory disease. Frontiers in Immunology. 3: 315. PMID 23087690 DOI: 10.3389/Fimmu.2012.00315 |
0.322 |
|
2012 |
Lukens JR, Kanneganti TD. Fat chance: not much against NKT cells. Immunity. 37: 447-9. PMID 22999952 DOI: 10.1016/J.Immuni.2012.09.006 |
0.317 |
|
2012 |
Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M, Kanneganti TD. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature. 488: 389-93. PMID 22763455 DOI: 10.1038/Nature11250 |
0.37 |
|
2012 |
Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD. Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 3107-15. PMID 22345669 DOI: 10.4049/Jimmunol.1103308 |
0.35 |
|
2011 |
Shaw PJ, Barr MJ, Lukens JR, McGargill MA, Chi H, Mak TW, Kanneganti TD. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity. 34: 75-84. PMID 21236705 DOI: 10.1016/J.Immuni.2010.12.015 |
0.364 |
|
2010 |
Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD. Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 4610-4. PMID 20368281 DOI: 10.4049/Jimmunol.1000217 |
0.39 |
|
2010 |
Lassen MG, Lukens JR, Dolina JS, Brown MG, Hahn YS. Intrahepatic IL-10 maintains NKG2A+Ly49- liver NK cells in a functionally hyporesponsive state. Journal of Immunology (Baltimore, Md. : 1950). 184: 2693-701. PMID 20124099 DOI: 10.4049/Jimmunol.0901362 |
0.752 |
|
2009 |
Lukens JR, Dolina JS, Kim TS, Tacke RS, Hahn YS. Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system. Plos One. 4: e7619. PMID 19876399 DOI: 10.1371/Journal.Pone.0007619 |
0.781 |
|
2008 |
Lukens JR, Cruise MW, Lassen MG, Hahn YS. Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model. Journal of Immunology (Baltimore, Md. : 1950). 180: 4875-84. PMID 18354211 DOI: 10.4049/Jimmunol.180.7.4875 |
0.745 |
|
2007 |
Hwang ML, Lukens JR, Bullock TN. Cognate memory CD4+ T cells generated with dendritic cell priming influence the expansion, trafficking, and differentiation of secondary CD8+ T cells and enhance tumor control. Journal of Immunology (Baltimore, Md. : 1950). 179: 5829-38. PMID 17947656 DOI: 10.4049/Jimmunol.179.9.5829 |
0.342 |
|
2006 |
Cruise MW, Lukens JR, Nguyen AP, Lassen MG, Waggoner SN, Hahn YS. Fas ligand is responsible for CXCR3 chemokine induction in CD4+ T cell-dependent liver damage. Journal of Immunology (Baltimore, Md. : 1950). 176: 6235-44. PMID 16670334 DOI: 10.4049/Jimmunol.176.10.6235 |
0.738 |
|
2005 |
Cruise MW, Melief HM, Lukens J, Soguero C, Hahn YS. Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation. Journal of Leukocyte Biology. 78: 412-25. PMID 15894587 DOI: 10.1189/Jlb.0105005 |
0.777 |
|
2005 |
Cruise M, Lukens J, Hahn Y. Hepatitis C Viruss Immune Evasion Strategies Current Immunology Reviews. 1: 223-235. DOI: 10.2174/157339505774479275 |
0.738 |
|
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