Alan Lomax, PhD - Publications

Affiliations: 
Queen's University, Kingston, ON, Canada 
Area:
Enteric nervous system, autonomic nervous system

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Baker CC, Sessenwein JL, Wood HM, Yu Y, Tsang Q, Alward TA, Jimenez Vargas NN, Omar AA, McDonnel A, Segal J, Sjaarda CP, Bunnett NW, Schmidt BL, Caminero A, Boev N, ... ... Lomax AE, et al. Protease-induced excitation of dorsal root ganglion neurons in response to acute perturbation of the gut microbiota is associated with visceral and somatic hypersensitivity. Cellular and Molecular Gastroenterology and Hepatology. PMID 38494056 DOI: 10.1016/j.jcmgh.2024.03.006  0.344
2023 King JW, Bennett ASW, Wood HM, Baker CC, Alsaadi H, Topley M, Vanner SA, Reed DE, Lomax AE. Expression and function of transient receptor potential melastatin 3 in the spinal afferent innervation of the mouse colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 38084411 DOI: 10.1152/ajpgi.00230.2023  0.384
2023 Osman S, Tashtush A, Reed DE, Lomax AE. Analysis of the spinal and vagal afferent innervation of the mouse colon using neuronal retrograde tracers. Cell and Tissue Research. PMID 37004577 DOI: 10.1007/s00441-023-03769-3  0.386
2020 Pradhananga S, Tashtush AA, Allen-Vercoe E, Petrof EO, Lomax AE. Protease-dependent excitation of nodose ganglion neurons by commensal gut bacteria. The Journal of Physiology. PMID 32134496 DOI: 10.1113/JP279075  0.367
2020 Osman S, Lomax AE. A130 RETROGRADE TRACING ANALYSIS OF THE SENSORY INNERVATION OF THE MOUSE COLON Journal of the Canadian Association of Gastroenterology. 3: 150-151. DOI: 10.1093/jcag/gwz047.129  0.345
2019 Lomax AE, Pradhananga S, Sessenwein JL, O'Malley D. Bacterial modulation of visceral sensation: mediators and mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31290688 DOI: 10.1152/ajpgi.00052.2019  0.361
2019 Yu Y, Villalobos-Hernandez EC, Pradhananga S, Baker CC, Keating C, Grundy D, Lomax AE, Reed DE. Deoxycholic acid activates colonic afferent nerves via 5-HT receptor dependent and independent mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31216174 DOI: 10.1152/ajpgi.00016.2019  0.334
2019 Shimbori C, Palma GD, Reed D, Pigrau M, Lu J, Zhang Y, Yu Y, Jimenez-Vargas N, Sessenwein J, Lopez-Lopez C, Jaramillo-Polanco J, Verdu E, Lomax A, Beyak M, Collins S, et al. Abstract # 3094 Microbiota-neuroimmune interactions in a humanized mouse model of IBS: The role of diet and mast cells Brain Behavior and Immunity. 76. DOI: 10.1016/J.Bbi.2018.11.220  0.316
2018 Reardon C, Murray K, Lomax AE. Neuroimmune Communication in Health and Disease. Physiological Reviews. 98: 2287-2316. PMID 30109819 DOI: 10.1152/physrev.00035.2017  0.32
2018 Pradhananga S, Lomax AE, Allen-Vercoe E, Petrof EO. A283 SECRETIONS OF INTESTINAL MICROBIOTA INCREASE THE EXCITABILITY OF VAGAL AFFERENT NEURONS VIA A PROTEASE ACTIVATED RECEPTOR 2 (PAR2)-DEPENDENT PATHWAY. Journal of the Canadian Association of Gastroenterology. 1: 408-408. DOI: 10.1093/jcag/gwy009.283  0.337
2017 Sessenwein JL, Baker CC, Pradhananga S, Maitland ME, Petrof EO, Allen-Vercoe E, Noordhof C, Reed DE, Vanner SJ, Lomax AE. Protease-mediated suppression of DRG neuron excitability by commensal bacteria. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29089436 DOI: 10.1523/JNEUROSCI.1672-17.2017  0.415
2017 Cervi AL, Moynes DM, Chisholm SP, Nasser Y, Vanner SJ, Lomax AE. A role for interleukin 17A in IBD-related neuroplasticity. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 29. PMID 28560787 DOI: 10.1111/Nmo.13112  0.527
2017 Stamp LA, Gwynne RM, Foong JP, Lomax AE, Hao MM, Kaplan DI, Reid CA, Petrou S, Allen AM, Bornstein JC, Young HM. Optogenetic demonstration of functional innervation of mouse colon by neurons derived from transplanted neural cells. Gastroenterology. PMID 28115057 DOI: 10.1053/j.gastro.2017.01.005  0.34
2017 Lomax AE, Pradhananga S, Bertrand PP. Plasticity of neuroeffector transmission during bowel inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00365.2016. PMID 28082285 DOI: 10.1152/ajpgi.00365.2016  0.341
2016 Guerrero-Alba R, Valdez Morales EE, Jimenez-Vargas JN, Lopez Lopez C, Jaramillo Polanco J, Okamoto T, Nasser Y, Bunnett NW, Lomax AE, Vanner SJ. Stress activates pronociceptive endogenous opioid signalling in DRG neurons during chronic colitis. Gut. PMID 27590998 DOI: 10.1136/Gutjnl-2016-311456  0.576
2016 Bertrand PP, Polglaze KE, Chen H, Sandow SL, Walduck A, Jenkins TA, Bertrand RL, Lomax AE, Liu L. Excitability and Synaptic Transmission in the Enteric Nervous System: Does Diet Play a Role? Advances in Experimental Medicine and Biology. 891: 201-211. PMID 27379647 DOI: 10.1007/978-3-319-27592-5_19  0.302
2016 Jiménez-Vargas NN, Poole DP, Lopez CDL, Polanco JOJ, Lomax AE, Bunnett N, Vanner S. Sa1840 Endogenous Opioids Evoke a Sustained Antinociceptive Effect via Endosomal Signaling in Nociceptive DRG Neurons Gastroenterology. 150: S378. DOI: 10.1016/S0016-5085(16)31329-4  0.347
2015 Lukewich MK, Lomax AE. Mouse models of sepsis elicit spontaneous action potential discharge and enhance intracellular Ca2+ signaling in postganglionic sympathetic neurons. Neuroscience. 284: 668-77. PMID 25450963 DOI: 10.1016/j.neuroscience.2014.10.039  0.386
2014 Benson JR, Xu J, Moynes DM, Lapointe TK, Altier C, Vanner SJ, Lomax AE. Sustained neurochemical plasticity in central terminals of mouse DRG neurons following colitis. Cell and Tissue Research. 356: 309-17. PMID 24715114 DOI: 10.1007/s00441-014-1832-x  0.399
2014 Lukewich MK, Rogers RC, Lomax AE. Divergent neuroendocrine responses to localized and systemic inflammation. Seminars in Immunology. 26: 402-8. PMID 24486057 DOI: 10.1016/j.smim.2014.01.004  0.326
2014 Moynes DM, Lucas GH, Beyak MJ, Lomax AE. Effects of inflammation on the innervation of the colon. Toxicologic Pathology. 42: 111-7. PMID 24159054 DOI: 10.1177/0192623313505929  0.322
2014 Guerrero-Alba R, Valdez-Morales EE, Lomax A, Vanner SJ. Tu1715 Mu and Delta Opioid Signaling Is Switched by Chronic Inflammation in Sensory Dorsal Root Ganglia Neurons Gastroenterology. 146: S-824-S-825. DOI: 10.1016/S0016-5085(14)62992-9  0.448
2014 Valdez-Morales EE, Lomax A, Vanner SJ. Tu1707 Endogenous Opioids From Human IBD Supernatants Modulate TRPV1 on DRG Neurons During Chronic Colitis Gastroenterology. 146: S-823. DOI: 10.1016/S0016-5085(14)62984-X  0.407
2013 Hao MM, Bornstein JC, Vanden Berghe P, Lomax AE, Young HM, Foong JP. The emergence of neural activity and its role in the development of the enteric nervous system. Developmental Biology. 382: 365-74. PMID 23261929 DOI: 10.1016/j.ydbio.2012.12.006  0.32
2013 Valdez-Morales E, Guerrero-Alba R, Ochoa-Cortes F, Benson J, Spreadbury I, Hurlbut D, Miranda-Morales M, Lomax AE, Vanner S. Release of endogenous opioids during a chronic IBD model suppresses the excitability of colonic DRG neurons. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 25: 39-46.e4. PMID 22963585 DOI: 10.1111/nmo.12008  0.69
2013 Zhang Y, Beyak MJ, Lomax A, MacDonald H, Paterson WG, Vanner SJ. 162 Potentiation of Descending Inhibition to Colonic Circular Smooth Muscle of Mice and Humans by Chronic Stress and Stress Hormones: A Mechanism for Stress-Induced Diarrhea? Gastroenterology. 144: S-37-S-38. DOI: 10.1016/S0016-5085(13)60133-X  0.339
2012 Roberts JA, Lukewich MK, Sharkey KA, Furness JB, Mawe GM, Lomax AE. The roles of purinergic signaling during gastrointestinal inflammation. Current Opinion in Pharmacology. 12: 659-66. PMID 23063457 DOI: 10.1016/J.Coph.2012.09.011  0.53
2012 Hao MM, Lomax AE, McKeown SJ, Reid CA, Young HM, Bornstein JC. Early development of electrical excitability in the mouse enteric nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10949-60. PMID 22875929 DOI: 10.1523/JNEUROSCI.1426-12.2012  0.318
2012 Furness JB, Cho HJ, Hunne B, Hirayama H, Callaghan BP, Lomax AE, Brock JA. Identification of neurons that express ghrelin receptors in autonomic pathways originating from the spinal cord. Cell and Tissue Research. 348: 397-405. PMID 22538519 DOI: 10.1007/S00441-012-1405-9  0.376
2012 Valdez-Morales E, Benson J, Lomax A, Vanner SJ. 637 Activation of Mu-Opioid Receptors Decreases Excitability of Colonic Dorsal Root Ganglion Neurons by Enhancing Voltage Gated Potassium Channels in a Chronic Mouse Model of Inflammatory Bowel Disease Gastroenterology. 142: S-126. DOI: 10.1016/S0016-5085(12)60477-6  0.455
2010 Lomax AE, Sharkey KA, Furness JB. The participation of the sympathetic innervation of the gastrointestinal tract in disease states. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 7-18. PMID 19686308 DOI: 10.1111/J.1365-2982.2009.01381.X  0.534
2010 Chisholm S, Nagpal S, Lomax A. T2046 Colitis and Interleukin 17a Enhance Neurite Extension in Adult Sympathetic Neurons That Innervate the Gut Gastroenterology. 138: S-620. DOI: 10.1016/S0016-5085(10)62859-4  0.388
2009 Boissé L, Chisholm SP, Lukewich MK, Lomax AE. Clinical and experimental evidence of sympathetic neural dysfunction during inflammatory bowel disease. Clinical and Experimental Pharmacology & Physiology. 36: 1026-33. PMID 19566829 DOI: 10.1111/j.1440-1681.2009.05242.x  0.351
2008 Motagally M, Neshat S, Lomax A. W1372 Colitis Reduces N-Type Ca2+ Current in Neurons from Superior Mesenteric Ganglia Gastroenterology. 134: A-690. DOI: 10.1016/S0016-5085(08)63222-9  0.373
2008 Motagally M, Neshat S, Lomax A. 48 Tumour Necrosis Factor α Activates NFκB to Inhibit N-Type Voltage-Gated Ca2+ Current in Postganglionic Sympathetic Neurons Gastroenterology. 134: A-7. DOI: 10.1016/S0016-5085(08)60043-8  0.345
2007 Lomax AE, O'Hara JR, Hyland NP, Mawe GM, Sharkey KA. Persistent alterations to enteric neural signaling in the guinea pig colon following the resolution of colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G482-91. PMID 17008554 DOI: 10.1152/Ajpgi.00355.2006  0.695
2007 O'Hara JR, Lomax AE, Mawe GM, Sharkey KA. Ileitis alters neuronal and enteroendocrine signalling in guinea pig distal colon. Gut. 56: 186-94. PMID 16931576 DOI: 10.1136/Gut.2006.102780  0.679
2006 Lomax AE, Linden DR, Mawe GM, Sharkey KA. Effects of gastrointestinal inflammation on enteroendocrine cells and enteric neural reflex circuits. Autonomic Neuroscience : Basic & Clinical. 126: 250-7. PMID 16616704 DOI: 10.1016/J.Autneu.2006.02.015  0.614
2005 Lomax AE, Mawe GM, Sharkey KA. Synaptic facilitation and enhanced neuronal excitability in the submucosal plexus during experimental colitis in guinea-pig. The Journal of Physiology. 564: 863-75. PMID 15774518 DOI: 10.1113/Jphysiol.2005.084285  0.581
2005 Lomax AE, Fernández E, Sharkey KA. Plasticity of the enteric nervous system during intestinal inflammation. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 17: 4-15. PMID 15670258 DOI: 10.1111/j.1365-2982.2004.00607.x  0.567
2003 Lomax AE, Sharkey KA, Giles WR. Neuropeptide y modulates L-type Ca2+ current during heart development. Circulation Research. 93: 891-2. PMID 14615491 DOI: 10.1161/01.Res.0000103310.15593.C5  0.403
2001 Lomax AE, Bertrand PP, Furness JB. Electrophysiological characteristics distinguish three classes of neuron in submucosal ganglia of the guinea-pig distal colon. Neuroscience. 103: 245-55. PMID 11311805 DOI: 10.1016/S0306-4522(00)00545-5  0.388
2000 Lomax AE, Furness JB. Neurochemical classification of enteric neurons in the guinea-pig distal colon. Cell and Tissue Research. 302: 59-72. PMID 11079716 DOI: 10.1007/S004410000260  0.373
2000 Lomax AE, Zhang JY, Furness JB. Origins of cholinergic inputs to the cell bodies of intestinofugal neurons in the guinea pig distal colon. The Journal of Comparative Neurology. 416: 451-60. PMID 10660877 DOI: 10.1002/(Sici)1096-9861(20000124)416:4<451::Aid-Cne3>3.0.Co;2-E  0.39
1999 Lomax AE, Sharkey KA, Bertrand PP, Low AM, Bornstein JC, Furness JB. Correlation of morphology, electrophysiology and chemistry of neurons in the myenteric plexus of the guinea-pig distal colon. Journal of the Autonomic Nervous System. 76: 45-61. PMID 10323306 DOI: 10.1016/S0165-1838(99)00008-9  0.558
1998 Sharkey KA, Lomax AE, Bertrand PP, Furness JB. Electrophysiology, shape, and chemistry of neurons that project from guinea pig colon to inferior mesenteric ganglia. Gastroenterology. 115: 909-18. PMID 9753494 DOI: 10.1016/S0016-5085(98)70263-X  0.57
1998 Lomax AE, Bertrand PP, Furness JB. Identification of the populations of enteric neurons that have NK1 tachykinin receptors in the guinea-pig small intestine. Cell and Tissue Research. 294: 27-33. PMID 9724453 DOI: 10.1007/S004410051153  0.361
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