Randolph J. Noelle - Publications

Affiliations: 
Immunology and Microbiology Dartmouth College, Hanover, NH, United States 
Area:
Microbiology Biology, Immunology

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Noelle RJ, Lines JL, Lewis LD, Martell RE, Guillaudeux T, Lee SW, Mahoney KM, Vesely MD, Boyd-Kirkup J, Nambiar DK, Scott AM. Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights. Frontiers in Oncology. 13: 1225081. PMID 37795437 DOI: 10.3389/fonc.2023.1225081  0.413
2023 Martin AS, Molloy M, Ugolkov A, von Roemeling RW, Noelle RJ, Lewis LD, Johnson M, Radvanyi L, Martell RE. VISTA expression and patient selection for immune-based anticancer therapy. Frontiers in Immunology. 14: 1086102. PMID 36891296 DOI: 10.3389/fimmu.2023.1086102  0.421
2022 Schaafsma E, Croteau W, ElTanbouly MA, Nowak EC, Smits NC, Deng J, Sarde A, Webber CA, Rabadi D, Cheng C, Noelle R, Lines JL. VISTA targeting of T-cell quiescence and myeloid suppression overcomes adaptive resistance. Cancer Immunology Research. PMID 36260656 DOI: 10.1158/2326-6066.CIR-22-0116  0.398
2022 Contreras-Kallens P, Gálvez-Jirón F, De Solminihac J, Elhusseiny A, González-Arriagada WA, Alcayaga-Miranda F, Noelle RJ, Pino-Lagos K. CD49b Targeting Inhibits Tumor Growth and Boosts Anti-tumor Immunity. Frontiers in Oncology. 12: 928498. PMID 35860556 DOI: 10.3389/fonc.2022.928498  0.787
2022 Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, ... ... Noelle RJ, et al. Retinoic acid signaling acts as a rheostat to balance Treg function. Cellular & Molecular Immunology. PMID 35581350 DOI: 10.1038/s41423-022-00869-y  0.381
2021 Fadul CE, Mao-Draayer Y, Ryan KA, Noelle RJ, Wishart HA, Channon JY, Kasper IR, Oliver B, Mielcarz DW, Kasper LH. Safety and Immune Effects of Blocking CD40 Ligand in Multiple Sclerosis. Neurology(R) Neuroimmunology & Neuroinflammation. 8. PMID 34654708 DOI: 10.1212/NXI.0000000000001096  0.351
2021 Borggrewe M, Kooistra SM, Wesseling EM, Gierschek FL, Brummer ML, Nowak EC, Medeiros-Furquim T, Otto TA, Lee SW, Noelle RJ, Eggen BJL, Laman JD. VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology. Acta Neuropathologica Communications. 9: 91. PMID 34006329 DOI: 10.1186/s40478-021-01186-7  0.327
2021 Fanelli G, Romano M, Nova-Lamperti E, Werner Sunderland M, Nerviani A, Scottà C, Bombardieri M, Quezada SA, Sacks SH, Noelle RJ, Pitzalis C, Lechler RI, Lombardi G, Becker PD. PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype. Plos Biology. 19: e3001199. PMID 33901179 DOI: 10.1371/journal.pbio.3001199  0.328
2020 ElTanbouly MA, Zhao Y, Schaafsma E, Burns CM, Mabaera R, Cheng C, Noelle RJ. VISTA: A Target to Manage the Innate Cytokine Storm. Frontiers in Immunology. 11: 595950. PMID 33643285 DOI: 10.3389/fimmu.2020.595950  0.416
2020 ElTanbouly MA, Noelle RJ. Rethinking peripheral T cell tolerance: checkpoints across a T cell's journey. Nature Reviews. Immunology. PMID 33077935 DOI: 10.1038/s41577-020-00454-2  0.401
2020 Thangavelu G, Wang C, Loschi M, Saha A, Osborn M, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, ... ... Noelle RJ, et al. Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses. Blood. PMID 32976550 DOI: 10.1182/blood.2020005628  0.418
2020 Borggrewe M, Kooistra SM, Noelle RJ, Eggen BJL, Laman JD. Exploring the VISTA of microglia: immune checkpoints in CNS inflammation. Journal of Molecular Medicine (Berlin, Germany). PMID 32856125 DOI: 10.1007/S00109-020-01968-X  0.464
2020 Alhabbab R, Blair P, Elgueta R, Stolarczyk E, Marks E, Becker PD, Ratnasothy K, Smyth L, Safinia N, Sharif-Paghaleh E, O'Connell S, Noelle RJ, Lord GM, Howard JK, Spencer J, et al. Author Correction: Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model. Scientific Reports. 10: 6166. PMID 32249800 DOI: 10.1038/S41598-020-62381-5  0.324
2020 ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, ... ... Noelle RJ, et al. VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance. Science (New York, N.Y.). 367. PMID 31949051 DOI: 10.1126/Science.Aay0524  0.503
2020 ElTanbouly MA, Schaafsma E, Noelle RJ, Lines JL. VISTA: Coming of age as a multi-lineage immune checkpoint. Clinical and Experimental Immunology. PMID 31930484 DOI: 10.1111/Cei.13415  0.468
2019 Broughton TWK, ElTanbouly MA, Schaafsma E, Deng J, Sarde A, Croteau W, Li J, Nowak EC, Mabaera R, Smits NC, Kuta A, Noelle RJ, Lines JL. Defining the Signature of VISTA on Myeloid Cell Chemokine Responsiveness. Frontiers in Immunology. 10: 2641. PMID 31803182 DOI: 10.3389/Fimmu.2019.02641  0.42
2019 ElTanbouly MA, Croteau W, Noelle RJ, Lines JL. VISTA: a novel immunotherapy target for normalizing innate and adaptive immunity. Seminars in Immunology. 42: 101308. PMID 31604531 DOI: 10.1016/J.Smim.2019.101308  0.448
2019 Deng J, Li J, Sarde A, Lines JL, Lee YC, Qian DC, Pechenick DA, Manivanh R, Le Mercier I, Lowrey CH, Varn FS, Cheng C, Leib DA, Noelle RJ, Mabaera R. Hypoxia-induced VISTA promotes the suppressive function of myeloid- derived suppressor cells in the tumor microenvironment. Cancer Immunology Research. PMID 31088847 DOI: 10.1158/2326-6066.Cir-18-0507  0.427
2019 Thangavelu G, Lee YC, Loschi M, Schaechter KM, Feser CJ, Koehn BH, Nowak EC, Zeiser R, Serody JS, Murphy WJ, Munn DH, Chambon P, Noelle RJ, Blazar BR. Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. Journal of Immunology (Baltimore, Md. : 1950). PMID 30885956 DOI: 10.4049/Jimmunol.1800899  0.487
2019 Shah P, Eltanbouly M, Smits N, Sarde A, Noelle R, Mabaera R. VISTA Is a Novel Regulator of Macrophage Biology Blood. 134: 2320-2320. DOI: 10.1182/Blood-2019-131310  0.45
2018 Borggrewe M, Grit C, Den Dunnen WFA, Burm SM, Bajramovic JJ, Noelle RJ, Eggen BJL, Laman JD. VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases. Glia. PMID 30306644 DOI: 10.1002/Glia.23517  0.372
2018 Kuklinski LF, Yan S, Li Z, Fisher JL, Cheng C, Noelle RJ, Angeles CV, Turk MJ, Ernstoff MS. VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival. Cancer Immunology, Immunotherapy : Cii. PMID 29737375 DOI: 10.1007/S00262-018-2169-1  0.446
2017 Laman JD, Claassen E, Noelle RJ. Functions of CD40 and Its Ligand, gp39 (CD40L). Critical Reviews in Immunology. 37: 371-420. PMID 29773027 DOI: 10.1615/Critrevimmunol.V37.I2-6.100  0.525
2017 Ceeraz S, Eszterhas SK, Sergent PA, Armstrong DA, Ashare A, Broughton T, Wang L, Pechenick D, Burns CM, Noelle RJ, Vincenti MP, Fava RA. VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes. Arthritis Research & Therapy. 19: 270. PMID 29216931 DOI: 10.1186/S13075-017-1474-Y  0.496
2017 Sergent PA, Plummer SF, Pettus J, Mabaera R, DeLong JK, Pechenick DA, Burns CM, Noelle RJ, Ceeraz S. Blocking the VISTA pathway enhances disease progression in (NZB × NZW) F1 female mice. Lupus. 961203317716322. PMID 28659048 DOI: 10.1177/0961203317716322  0.402
2017 Khan AA, Srivastava R, Chentoufi AA, Kritzer E, Chilukuri S, Garg S, Yu DC, Vahed H, Huang L, Syed SA, Furness JN, Tran TT, Anthony NB, McLaren CE, Sidney J, ... ... Noelle RJ, et al. Bolstering the Number and Function of HSV-1-Specific CD8(+) Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 28539429 DOI: 10.4049/Jimmunol.1700145  0.523
2017 Nowak EC, Lines JL, Varn FS, Deng J, Sarde A, Mabaera R, Kuta A, Le Mercier I, Cheng C, Noelle RJ. Immunoregulatory functions of VISTA. Immunological Reviews. 276: 66-79. PMID 28258694 DOI: 10.1111/Imr.12525  0.325
2016 Marks E, Ortiz C, Pantazi E, Bailey CS, Lord GM, Waldschmidt TJ, Noelle RJ, Elgueta R. Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response. Frontiers in Immunology. 7: 643. PMID 28066447 DOI: 10.3389/Fimmu.2016.00643  0.47
2016 Deng J, Le Mercier I, Kuta A, Noelle RJ. A New VISTA on combination therapy for negative checkpoint regulator blockade. Journal For Immunotherapy of Cancer. 4: 86. PMID 28031817 DOI: 10.1186/S40425-016-0190-5  0.375
2016 Ceeraz S, Sergent PA, Plummer SF, Schned AR, Pechenick D, Burns CM, Noelle RJ. VISTA deficiency accelerates the development of fatal murine lupus nephritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27992697 DOI: 10.1002/Art.40020  0.446
2016 Noelle RJ, Roy M, Shepherd DM, Stamenkovico I, Ledbetter JA, Aruffo A. Pillars Article: A 39-kDa Protein on Activated Helper T Cells Binds CD40 and Transduces the Signal for Cognate Activation of B Cells. Proc. Natl. Acad. Sci. 1992. 89: 6550-6554. Journal of Immunology (Baltimore, Md. : 1950). 197: 4195-4199. PMID 27864550  0.397
2016 Elgueta R, Tse D, Deharvengt SJ, Luciano MR, Carriere C, Noelle RJ, Stan RV. Endothelial Plasmalemma Vesicle-Associated Protein Regulates the Homeostasis of Splenic Immature B Cells and B-1 B Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27742829 DOI: 10.4049/Jimmunol.1501859  0.401
2016 Gajardo T, Pérez F, Terraza C, Campos-Mora M, Noelle RJ, Pino-Lagos K. IL-33 enhances retinoic acid signaling on CD4+ T cells. Cytokine. 85: 120-122. PMID 27322964 DOI: 10.1016/J.Cyto.2016.06.016  0.746
2016 Chandraratna RA, Noelle RJ, Nowak EC. Treatment with retinoid X receptor agonist IRX4204 ameliorates experimental autoimmune encephalomyelitis. American Journal of Translational Research. 8: 1016-26. PMID 27158387  0.464
2016 Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, Hartwig H, Beckers L, Megens RT, Boon L, Noelle RJ, Soehnlein O, Heemskerk JW, Weber C, Lutgens E. Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 482-90. PMID 26821950 DOI: 10.1161/Atvbaha.115.307074  0.424
2016 Thangavelu G, Saha A, Aoyama K, McDonald-Hyman C, Lee Y, Brown C, Panoskaltsis-Mortari A, Osborn MJ, Chandraratna RA, Noelle R, Blazar BR. Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease Blood. 128: 4534-4534. DOI: 10.1182/Blood.V128.22.4534.4534  0.497
2015 Le Mercier I, Lines JL, Noelle RJ. Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators. Frontiers in Immunology. 6: 418. PMID 26347741 DOI: 10.3389/Fimmu.2015.00418  0.392
2015 Brown C, Esterhazy D, Sarde A, Pullabhatla V, London M, Arno M, de Rinaldis E, Mucida D, Lord G, Noelle R. Role of retinoic acid in the stability of the T-helper-type 1 lineage and implications for autoimmunity. Lancet (London, England). 385: S25. PMID 26312847 DOI: 10.1016/S0140-6736(15)60340-3  0.521
2015 Pantazi E, Marks E, Stolarczyk E, Lycke N, Noelle RJ, Elgueta R. Cutting Edge: Retinoic Acid Signaling in B Cells Is Essential for Oral Immunization and Microflora Composition. Journal of Immunology (Baltimore, Md. : 1950). 195: 1368-71. PMID 26163586 DOI: 10.4049/Jimmunol.1500989  0.446
2015 Green KA, Wang L, Noelle RJ, Green WR. Selective Involvement of the Checkpoint Regulator VISTA in Suppression of B-cell, but not T-cell, Responsiveness by Monocytic Myeloid Derived Suppressor Cells from Mice Infected by an Immunodeficiency-causing Retrovirus. Journal of Virology. PMID 26157131 DOI: 10.1128/Jvi.00888-15  0.498
2015 Alhabbab R, Blair P, Elgueta R, Stolarczyk E, Marks E, Becker PD, Ratnasothy K, Smyth L, Safinia N, Sharif-Paghaleh E, O'Connell S, Noelle RJ, Lord GM, Howard JK, Spencer J, et al. Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model. Scientific Reports. 5: 11554. PMID 26109230 DOI: 10.1038/Srep11554  0.403
2015 Chai JG, Ratnasothy K, Bucy RP, Noelle RJ, Lechler R, Lombardi G. Allospecific CD4(+) T cells retain effector function and are actively regulated by Treg cells in the context of transplantation tolerance. European Journal of Immunology. 45: 2017-27. PMID 25944401 DOI: 10.1002/Eji.201545455  0.548
2015 Brown CC, Noelle RJ. Seeing through the dark: New insights into the immune regulatory functions of vitamin A. European Journal of Immunology. 45: 1287-95. PMID 25808452 DOI: 10.1002/Eji.201344398  0.428
2015 Brown CC, Esterhazy D, Sarde A, London M, Pullabhatla V, Osma-Garcia I, Al-Bader R, Ortiz C, Elgueta R, Arno M, de Rinaldis E, Mucida D, Lord GM, Noelle RJ. Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program. Immunity. 42: 499-511. PMID 25769610 DOI: 10.1016/J.Immuni.2015.02.003  0.521
2015 Guo Y, Brown C, Ortiz C, Noelle RJ. Leukocyte homing, fate, and function are controlled by retinoic acid. Physiological Reviews. 95: 125-48. PMID 25540140 DOI: 10.1152/Physrev.00032.2013  0.619
2015 Elgueta R, Marks E, Nowak E, Menezes S, Benson M, Raman VS, Ortiz C, O'Connell S, Hess H, Lord GM, Noelle R. CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen. Journal of Immunology (Baltimore, Md. : 1950). 194: 505-13. PMID 25505290 DOI: 10.4049/Jimmunol.1401553  0.69
2015 de Vries VC, Le Mercier I, Nowak EC, Noelle RJ. Studying mast cells in peripheral tolerance by using a skin transplantation model. Methods in Molecular Biology (Clifton, N.J.). 1220: 461-86. PMID 25388268 DOI: 10.1007/978-1-4939-1568-2_28  0.796
2015 Elgueta R, Marks E, Nowak E, Menezes S, Benson M, Raman VS, Ortiz C, O'Connell S, Hess H, Lord GM, Noelle R. CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen Journal of Immunology. 194: 505-513. DOI: 10.4049/jimmunol.1401553  0.617
2014 Ceeraz S, Nowak EC, Burns CM, Noelle RJ. Immune checkpoint receptors in regulating immune reactivity in rheumatic disease. Arthritis Research & Therapy. 16: 469. PMID 25606596 DOI: 10.1186/S13075-014-0469-1  0.521
2014 Wang L, Le Mercier I, Putra J, Chen W, Liu J, Schenk AD, Nowak EC, Suriawinata AA, Li J, Noelle RJ. Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 111: 14846-51. PMID 25267631 DOI: 10.1073/Pnas.1407447111  0.503
2014 Lines JL, Sempere LF, Broughton T, Wang L, Noelle R. VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy. Cancer Immunology Research. 2: 510-7. PMID 24894088 DOI: 10.1158/2326-6066.Cir-14-0072  0.435
2014 Le Mercier I, Chen W, Lines JL, Day M, Li J, Sergent P, Noelle RJ, Wang L. VISTA Regulates the Development of Protective Antitumor Immunity. Cancer Research. 74: 1933-44. PMID 24691994 DOI: 10.1158/0008-5472.Can-13-1506  0.549
2014 Lines JL, Pantazi E, Mak J, Sempere LF, Wang L, O'Connell S, Ceeraz S, Suriawinata AA, Yan S, Ernstoff MS, Noelle R. VISTA is an immune checkpoint molecule for human T cells. Cancer Research. 74: 1924-32. PMID 24691993 DOI: 10.1158/0008-5472.Can-13-1504  0.5
2014 Guo Y, Lee YC, Brown C, Zhang W, Usherwood E, Noelle RJ. Dissecting the role of retinoic acid receptor isoforms in the CD8 response to infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 3336-44. PMID 24610012 DOI: 10.4049/Jimmunol.1301949  0.691
2014 Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, ... ... Noelle R, et al. Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 111: 2686-91. PMID 24492375 DOI: 10.1073/Pnas.1400419111  0.424
2014 Wang L, LeMercier I, Suriawinata A, Chen W, Noelle RJ, Li J. Abstract LB-157: VISTA deficiency synergizes with a non-redundant immune checkpoint pathway and leads to enhanced immune activation Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-157  0.519
2013 Ceeraz S, Nowak EC, Noelle RJ. B7 family checkpoint regulators in immune regulation and disease. Trends in Immunology. 34: 556-63. PMID 23954143 DOI: 10.1016/J.It.2013.07.003  0.414
2013 Aoyama K, Saha A, Tolar J, Riddle MJ, Veenstra RG, Taylor PA, Blomhoff R, Panoskaltsis-Mortari A, Klebanoff CA, Socié G, Munn DH, Murphy WJ, Serody JS, Fulton LM, Teshima T, ... ... Noelle RJ, et al. Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 122: 2125-34. PMID 23814022 DOI: 10.1182/Blood-2012-11-470252  0.66
2013 Allie SR, Zhang W, Tsai CY, Noelle RJ, Usherwood EJ. Critical role for all-trans retinoic acid for optimal effector and effector memory CD8 T cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 190: 2178-87. PMID 23338237 DOI: 10.4049/Jimmunol.1201945  0.524
2012 Nowak EC, de Vries VC, Wasiuk A, Ahonen C, Bennett KA, Le Mercier I, Ha DG, Noelle RJ. Tryptophan hydroxylase-1 regulates immune tolerance and inflammation. The Journal of Experimental Medicine. 209: 2127-35. PMID 23008335 DOI: 10.1084/Jem.20120408  0.802
2012 Guo Y, Pino-Lagos K, Ahonen CA, Bennett KA, Wang J, Napoli JL, Blomhoff R, Sockanathan S, Chandraratna RA, Dmitrovsky E, Turk MJ, Noelle RJ. A retinoic acid--rich tumor microenvironment provides clonal survival cues for tumor-specific CD8(+) T cells. Cancer Research. 72: 5230-9. PMID 22902413 DOI: 10.1158/0008-5472.Can-12-1727  0.818
2012 Wasiuk A, Dalton DK, Schpero WL, Stan RV, Conejo-Garcia JR, Noelle RJ. Mast cells impair the development of protective anti-tumor immunity. Cancer Immunology, Immunotherapy : Cii. 61: 2273-82. PMID 22684520 DOI: 10.1007/S00262-012-1276-7  0.808
2012 Dalton DK, Noelle RJ. The roles of mast cells in anticancer immunity. Cancer Immunology, Immunotherapy : Cii. 61: 1511-20. PMID 22527244 DOI: 10.1007/S00262-012-1246-0  0.507
2012 O'Connor RA, Li X, Blumerman S, Anderton SM, Noelle RJ, Dalton DK. Adjuvant immunotherapy of experimental autoimmune encephalomyelitis: immature myeloid cells expressing CXCL10 and CXCL16 attract CXCR3+CXCR6+ and myelin-specific T cells to the draining lymph nodes rather than the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 188: 2093-101. PMID 22287719 DOI: 10.4049/Jimmunol.1101118  0.565
2011 de Vries VC, Pino-Lagos K, Nowak EC, Bennett KA, Oliva C, Noelle RJ. Mast cells condition dendritic cells to mediate allograft tolerance. Immunity. 35: 550-61. PMID 22035846 DOI: 10.1016/J.Immuni.2011.09.012  0.814
2011 Pino-Lagos K, Guo Y, Brown C, Alexander MP, Elgueta R, Bennett KA, De Vries V, Nowak E, Blomhoff R, Sockanathan S, Chandraratna RA, Dmitrovsky E, Noelle RJ. A retinoic acid-dependent checkpoint in the development of CD4+ T cell-mediated immunity. The Journal of Experimental Medicine. 208: 1767-75. PMID 21859847 DOI: 10.1084/Jem.20102358  0.824
2011 Wang L, Rubinstein R, Lines JL, Wasiuk A, Ahonen C, Guo Y, Lu LF, Gondek D, Wang Y, Fava RA, Fiser A, Almo S, Noelle RJ. VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses. The Journal of Experimental Medicine. 208: 577-92. PMID 21383057 DOI: 10.1084/Jem.20100619  0.843
2010 Barth RJ, Fisher DA, Wallace PK, Channon JY, Noelle RJ, Gui J, Ernstoff MS. A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5548-56. PMID 20884622 DOI: 10.1158/1078-0432.Ccr-10-2138  0.425
2010 de Vries VC, Noelle RJ. Mast cell mediators in tolerance. Current Opinion in Immunology. 22: 643-8. PMID 20884193 DOI: 10.1016/J.Coi.2010.08.015  0.787
2010 Noelle RJ, Nowak EC. Cellular sources and immune functions of interleukin-9. Nature Reviews. Immunology. 10: 683-7. PMID 20847745 DOI: 10.1038/Nri2848  0.457
2010 de Vries VC, Elgueta R, Lee DM, Noelle RJ. Mast cell protease 6 is required for allograft tolerance. Transplantation Proceedings. 42: 2759-62. PMID 20832582 DOI: 10.1016/j.transproceed.2010.05.168  0.73
2010 Pino-Lagos K, Guo Y, Noelle RJ. Retinoic acid: a key player in immunity. Biofactors (Oxford, England). 36: 430-6. PMID 20803520 DOI: 10.1002/Biof.117  0.781
2010 Nowak EC, Noelle RJ. Interleukin-9 as a T helper type 17 cytokine. Immunology. 131: 169-73. PMID 20673237 DOI: 10.1111/J.1365-2567.2010.03332.X  0.427
2010 Elgueta R, de Vries VC, Noelle RJ. The immortality of humoral immunity. Immunological Reviews. 236: 139-50. PMID 20636814 DOI: 10.1111/J.1600-065X.2010.00924.X  0.791
2010 Gunturu KS, Meehan KR, Mackenzie TA, Crocenzi TS, McDermott D, Usherwood EJ, Margolin KA, Crosby NA, Atkins MB, Turk MJ, Ahonen C, Fuse S, Clark JI, Fisher JL, Noelle RJ, et al. Cytokine working group study of lymphodepleting chemotherapy, interleukin-2, and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma: clinical outcomes and peripheral-blood cell recovery. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1196-202. PMID 20124177 DOI: 10.1200/Jco.2009.24.8153  0.349
2010 Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, ... Noelle RJ, et al. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. The Journal of Experimental Medicine. 207: 391-404. PMID 20100871 DOI: 10.1084/Jem.20091293  0.461
2010 Elgueta R, De Vries VC, Noelle RJ. Mechanisms of cd40 signaling in the immune system Handbook of Cell Signaling, 2/E. 1: 353-358. DOI: 10.1016/B978-0-12-374145-5.00051-6  0.782
2010 Wasiuk A, De Vries VC, Nowak EC, Noelle RJ. Mast cells in allergy and tumor disease Cancer and Ige: Introducing the Concept of Allergooncology. 137-158. DOI: 10.1007/978-1-60761-451-7_6  0.79
2009 Nowak EC, Noelle RJ. Interleukin-9 and T cell subsets. Cell Cycle (Georgetown, Tex.). 8: 3798-9. PMID 19934658 DOI: 10.4161/Cc.8.23.10069  0.442
2009 Benson MJ, Elgueta R, Schpero W, Molloy M, Zhang W, Usherwood E, Noelle RJ. Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals. The Journal of Experimental Medicine. 206: 2013-25. PMID 19703988 DOI: 10.1084/Jem.20090667  0.672
2009 de Vries VC, Wasiuk A, Bennett KA, Benson MJ, Elgueta R, Waldschmidt TJ, Noelle RJ. Mast cell degranulation breaks peripheral tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 2270-80. PMID 19681828 DOI: 10.1111/J.1600-6143.2009.02755.X  0.799
2009 Schwaab T, Schwarzer A, Wolf B, Crocenzi TS, Seigne JD, Crosby NA, Cole BF, Fisher JL, Uhlenhake JC, Mellinger D, Foster C, Szczepiorkowski ZM, Webber SM, Schned AR, Harris RD, ... ... Noelle RJ, et al. Clinical and immunologic effects of intranodal autologous tumor lysate-dendritic cell vaccine with Aldesleukin (Interleukin 2) and IFN-{alpha}2a therapy in metastatic renal cell carcinoma patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4986-92. PMID 19622576 DOI: 10.1158/1078-0432.Ccr-08-3240  0.325
2009 Nowak EC, Weaver CT, Turner H, Begum-Haque S, Becher B, Schreiner B, Coyle AJ, Kasper LH, Noelle RJ. IL-9 as a mediator of Th17-driven inflammatory disease. The Journal of Experimental Medicine. 206: 1653-60. PMID 19596803 DOI: 10.1084/Jem.20090246  0.33
2009 de Vries VC, Pino-Lagos K, Elgueta R, Noelle RJ. The enigmatic role of mast cells in dominant tolerance. Current Opinion in Organ Transplantation. 14: 332-7. PMID 19581806 DOI: 10.1097/Mot.0B013E32832Ce87A  0.818
2009 Elgueta R, Benson MJ, de Vries VC, Wasiuk A, Guo Y, Noelle RJ. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunological Reviews. 229: 152-72. PMID 19426221 DOI: 10.1111/J.1600-065X.2009.00782.X  0.833
2009 Mucida D, Pino-Lagos K, Kim G, Nowak E, Benson MJ, Kronenberg M, Noelle RJ, Cheroutre H. Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells. Immunity. 30: 471-2; author reply . PMID 19371709 DOI: 10.1016/J.Immuni.2009.03.008  0.834
2009 Wasiuk A, de Vries VC, Hartmann K, Roers A, Noelle RJ. Mast cells as regulators of adaptive immunity to tumours. Clinical and Experimental Immunology. 155: 140-6. PMID 19077084 DOI: 10.1111/J.1365-2249.2008.03840.X  0.81
2008 Pino-Lagos K, Benson MJ, Noelle RJ. Retinoic acid in the immune system. Annals of the New York Academy of Sciences. 1143: 170-87. PMID 19076350 DOI: 10.1196/Annals.1443.017  0.806
2008 Gondek DC, Devries V, Nowak EC, Lu LF, Bennett KA, Scott ZA, Noelle RJ. Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 4752-60. PMID 18802078 DOI: 10.4049/Jimmunol.181.7.4752  0.43
2008 Wang L, Pino-Lagos K, de Vries VC, Guleria I, Sayegh MH, Noelle RJ. Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 9331-6. PMID 18599457 DOI: 10.1073/Pnas.0710441105  0.822
2008 Lind EF, Ahonen CL, Wasiuk A, Kosaka Y, Becher B, Bennett KA, Noelle RJ. Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens. Journal of Immunology (Baltimore, Md. : 1950). 181: 354-63. PMID 18566401 DOI: 10.4049/Jimmunol.181.1.354  0.822
2008 Benson MJ, Elgueta R, Noelle RJ. B cell survival: an unexpected mechanism of lymphocyte vitality. Immunology and Cell Biology. 86: 485-6. PMID 18490932 DOI: 10.1038/Icb.2008.35  0.69
2008 Benson MJ, Dillon SR, Castigli E, Geha RS, Xu S, Lam KP, Noelle RJ. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. Journal of Immunology (Baltimore, Md. : 1950). 180: 3655-9. PMID 18322170 DOI: 10.4049/Jimmunol.180.6.3655  0.663
2008 Ahonen CL, Wasiuk A, Fuse S, Turk MJ, Ernstoff MS, Suriawinata AA, Gorham JD, Kedl RM, Usherwood EJ, Noelle RJ. Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines. Blood. 111: 3116-25. PMID 18202224 DOI: 10.1182/Blood-2007-09-114371  0.812
2008 Donners MM, Beckers L, Lievens D, Munnix I, Heemskerk J, Janssen BJ, Wijnands E, Cleutjens J, Zernecke A, Weber C, Ahonen CL, Benbow U, Newby AC, Noelle RJ, Daemen MJ, et al. The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. Blood. 111: 4596-604. PMID 18195092 DOI: 10.1182/Blood-2007-05-088906  0.431
2007 Benson MJ, Pino-Lagos K, Rosemblatt M, Noelle RJ. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. The Journal of Experimental Medicine. 204: 1765-74. PMID 17620363 DOI: 10.1084/Jem.20070719  0.808
2007 Benson MJ, Erickson LD, Gleeson MW, Noelle RJ. Affinity of antigen encounter and other early B-cell signals determine B-cell fate. Current Opinion in Immunology. 19: 275-80. PMID 17433651 DOI: 10.1016/J.Coi.2007.04.009  0.77
2007 Raman VS, Lind EF, Benson MJ, Noelle RJ. Strategies for selective priming of memory B cells. Immunology Letters. 109: 93-100. PMID 17374402 DOI: 10.1016/J.Imlet.2007.01.010  0.669
2007 Lu LF, Ahonen CL, Lind EF, Raman VS, Cook WJ, Lin LL, Noelle RJ. The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation. Blood. 110: 193-200. PMID 17360936 DOI: 10.1182/Blood-2006-07-038414  0.516
2007 Ernstoff MS, Crocenzi TS, Seigne JD, Crosby NA, Cole BF, Fisher JL, Uhlenhake JC, Mellinger D, Foster C, Farnham CJ, Mackay K, Szczepiorkowski ZM, Webber SM, Schned AR, Harris RD, ... ... Noelle RJ, et al. Developing a rational tumor vaccine therapy for renal cell carcinoma: immune yin and yang. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 733s-740s. PMID 17255302 DOI: 10.1158/1078-0432.Ccr-06-2064  0.405
2006 O'Connor BP, Vogel LA, Zhang W, Loo W, Shnider D, Lind EF, Ratliff M, Noelle RJ, Erickson LD. Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor. Journal of Immunology (Baltimore, Md. : 1950). 177: 7723-32. PMID 17114443 DOI: 10.4049/Jimmunol.177.11.7723  0.399
2006 Lu LF, Lind EF, Gondek DC, Bennett KA, Gleeson MW, Pino-Lagos K, Scott ZA, Coyle AJ, Reed JL, Van Snick J, Strom TB, Zheng XX, Noelle RJ. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature. 442: 997-1002. PMID 16921386 DOI: 10.1038/Nature05010  0.829
2006 Wolniak KL, Noelle RJ, Waldschmidt TJ. Characterization of (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific germinal center B cells and antigen-binding B220- cells after primary NP challenge in mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 2072-9. PMID 16887965 DOI: 10.4049/Jimmunol.177.4.2072  0.389
2005 Lu LF, Gondek DC, Scott ZA, Noelle RJ. NF kappa B-inducing kinase deficiency results in the development of a subset of regulatory T cells, which shows a hyperproliferative activity upon glucocorticoid-induced TNF receptor family-related gene stimulation. Journal of Immunology (Baltimore, Md. : 1950). 175: 1651-7. PMID 16034105 DOI: 10.4049/Jimmunol.175.3.1651  0.534
2005 Guleria I, Khosroshahi A, Ansari MJ, Habicht A, Azuma M, Yagita H, Noelle RJ, Coyle A, Mellor AL, Khoury SJ, Sayegh MH. A critical role for the programmed death ligand 1 in fetomaternal tolerance. The Journal of Experimental Medicine. 202: 231-7. PMID 16027236 DOI: 10.1084/Jem.20050019  0.462
2005 Quezada SA, Bennett K, Blazar BR, Rudensky AY, Sakaguchi S, Noelle RJ. Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation. Journal of Immunology (Baltimore, Md. : 1950). 175: 771-9. PMID 16002673 DOI: 10.4049/Jimmunol.175.2.771  0.568
2005 Greter M, Heppner FL, Lemos MP, Odermatt BM, Goebels N, Laufer T, Noelle RJ, Becher B. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis Nature Medicine. 11: 328-334. PMID 15735653 DOI: 10.1038/Nm1197  0.528
2005 Gondek DC, Lu LF, Quezada SA, Sakaguchi S, Noelle RJ. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 174: 1783-6. PMID 15699103 DOI: 10.4049/Jimmunol.174.4.1783  0.526
2005 Taylor PA, Panoskaltsis-Mortari A, Freeman GJ, Sharpe AH, Noelle RJ, Rudensky AY, Mak TW, Serody JS, Blazar BR. Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM). Blood. 105: 3372-80. PMID 15618467 DOI: 10.1182/Blood-2004-10-3869  0.56
2005 Noelle RJ, Erickson LD. Determinations of B cell fate in immunity and autoimmunity. Current Directions in Autoimmunity. 8: 1-24. PMID 15564715 DOI: 10.1159/000082084  0.544
2004 Quezada SA, Jarvinen LZ, Lind EF, Noelle RJ. CD40/CD154 interactions at the interface of tolerance and immunity. Annual Review of Immunology. 22: 307-28. PMID 15032580 DOI: 10.1146/Annurev.Immunol.22.012703.104533  0.511
2004 Ahonen CL, Doxsee CL, McGurran SM, Riter TR, Wade WF, Barth RJ, Vasilakos JP, Noelle RJ, Kedl RM. Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN. The Journal of Experimental Medicine. 199: 775-84. PMID 15007094 DOI: 10.1084/Jem.20031591  0.542
2004 O'Connor BP, Raman VS, Erickson LD, Cook WJ, Weaver LK, Ahonen C, Lin LL, Mantchev GT, Bram RJ, Noelle RJ. BCMA is essential for the survival of long-lived bone marrow plasma cells. The Journal of Experimental Medicine. 199: 91-8. PMID 14707116 DOI: 10.1084/Jem.20031330  0.337
2004 Taylor P, Panoskaltsis-Mortari A, Freeman G, Sharpe A, Noelle R, Rudensky A, Mak T, Serody J, Blazar B. The ICOS:ICOSL Costimulatory Pathway Plays an Important Role in GVHD and Bone Marrow (BM) Graft Rejection. Blood. 104: 591-591. DOI: 10.1182/Blood.V104.11.591.591  0.551
2004 Taylor P, Panoskaltsis-Mortari A, Noelle R, Rudensky A, Serody J, Blazar B. Visualizing Allogeneic Bone Marrow (BM) Graft Rejection. Blood. 104: 43-43. DOI: 10.1182/Blood.V104.11.43.43  0.483
2003 Jarvinen LZ, Blazar BR, Adeyi OA, Strom TB, Noelle RJ. CD154 on the surface of CD4+CD25+ regulatory T cells contributes to skin transplant tolerance. Transplantation. 76: 1375-9. PMID 14627918 DOI: 10.1097/01.Tp.0000093462.16309.73  0.507
2003 Becher B, Durell BG, Noelle RJ. IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. 112: 1186-91. PMID 14561703 DOI: 10.1172/Jci19079  0.39
2003 Erickson LD, Lin LL, Duan B, Morel L, Noelle RJ. A genetic lesion that arrests plasma cell homing to the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 100: 12905-10. PMID 14555759 DOI: 10.1073/Pnas.2131686100  0.401
2003 Quezada SA, Eckert M, Adeyi OA, Schned AR, Noelle RJ, Burns CM. Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis. Arthritis and Rheumatism. 48: 2541-54. PMID 13130474 DOI: 10.1002/Art.11230  0.378
2003 Frleta D, Noelle RJ, Wade WF. CD40-mediated up-regulation of Toll-like receptor 4-MD2 complex on the surface of murine dendritic cells. Journal of Leukocyte Biology. 74: 1064-73. PMID 12960264 DOI: 10.1189/Jlb.0203062  0.437
2003 Lu LF, Cook WJ, Lin LL, Noelle RJ. CD40 signaling through a newly identified tumor necrosis factor receptor-associated factor 2 (TRAF2) binding site. The Journal of Biological Chemistry. 278: 45414-8. PMID 12960157 DOI: 10.1074/Jbc.M309601200  0.436
2003 O'Connor BP, Gleeson MW, Noelle RJ, Erickson LD. The rise and fall of long-lived humoral immunity: terminal differentiation of plasma cells in health and disease. Immunological Reviews. 194: 61-76. PMID 12846808 DOI: 10.1034/J.1600-065X.2003.00055.X  0.724
2003 Quezada SA, Fuller B, Jarvinen LZ, Gonzalez M, Blazar BR, Rudensky AY, Strom TB, Noelle RJ. Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation. Blood. 102: 1920-6. PMID 12750162 DOI: 10.1182/Blood-2003-02-0586  0.495
2003 Sharp C, Thompson C, Samy ET, Noelle R, Tung KS. CD40 ligand in pathogenesis of autoimmune ovarian disease of day 3-thymectomized mice: implication for CD40 ligand antibody therapy. Journal of Immunology (Baltimore, Md. : 1950). 170: 1667-74. PMID 12574329 DOI: 10.4049/Jimmunol.170.4.1667  0.534
2003 Frleta D, Lin JT, Quezada SA, Wade TK, Barth RJ, Noelle RJ, Wade WF. Distinctive maturation of in vitro versus in vivo anti-CD40 mAb-matured dendritic cells in mice. Journal of Immunotherapy (Hagerstown, Md. : 1997). 26: 72-84. PMID 12514431 DOI: 10.1097/00002371-200301000-00008  0.466
2002 Gibson SJ, Lindh JM, Riter TR, Gleason RM, Rogers LM, Fuller AE, Oesterich JL, Gorden KB, Qiu X, McKane SW, Noelle RJ, Miller RL, Kedl RM, Fitzgerald-Bocarsly P, Tomai MA, et al. Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod. Cellular Immunology. 218: 74-86. PMID 12470615 DOI: 10.1016/S0008-8749(02)00517-8  0.37
2002 Gonzalez M, Quezada SA, Blazar BR, Panoskaltsis-Mortari A, Rudensky AY, Noelle RJ. The balance between donor T cell anergy and suppression versus lethal graft-versus-host disease is determined by host conditioning. Journal of Immunology (Baltimore, Md. : 1950). 169: 5581-9. PMID 12421935 DOI: 10.4049/Jimmunol.169.10.5581  0.527
2002 Taylor PA, Friedman TM, Korngold R, Noelle RJ, Blazar BR. Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell. Blood. 99: 4601-9. PMID 12036894 DOI: 10.1182/Blood.V99.12.4601  0.59
2002 Seo SJ, Fields ML, Buckler JL, Reed AJ, Mandik-Nayak L, Nish SA, Noelle RJ, Turka LA, Finkelman FD, Caton AJ, Erikson J. The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity. 16: 535-46. PMID 11970877 DOI: 10.1016/S1074-7613(02)00298-4  0.543
2002 Ahonen C, Manning E, Erickson LD, O'Connor B, Lind EF, Pullen SS, Kehry MR, Noelle RJ. The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells. Nature Immunology. 3: 451-6. PMID 11967542 DOI: 10.1038/Ni792  0.542
2002 O'Connor BP, Cascalho M, Noelle RJ. Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population. The Journal of Experimental Medicine. 195: 737-45. PMID 11901199 DOI: 10.1084/Jem.20011626  0.414
2002 Erickson LD, Durell BG, Vogel LA, O'Connor BP, Cascalho M, Yasui T, Kikutani H, Noelle RJ. Short-circuiting long-lived humoral immunity by the heightened engagement of CD40. The Journal of Clinical Investigation. 109: 613-20. PMID 11877469 DOI: 10.1172/Jci14110  0.562
2002 Li W, Buzoni-Gatel D, Debbabi H, Hu MS, Mennechet FJ, Durell BG, Noelle RJ, Kasper LH. CD40/CD154 ligation is required for the development of acute ileitis following oral infection with an intracellular pathogen in mice. Gastroenterology. 122: 762-73. PMID 11875009 DOI: 10.1053/Gast.2002.31888  0.394
2002 Fuller BW, Nishimura T, Noelle RJ. The selective triggering of CD40 on keratinocytes in vivo enhances cell-mediated immunity. European Journal of Immunology. 32: 895-902. PMID 11870634 DOI: 10.1002/1521-4141(200203)32:3<895::Aid-Immu895>3.0.Co;2-A  0.571
2002 Manning E, Pullen SS, Souza DJ, Kehry M, Noelle RJ. Cellular responses to murine CD40 in a mouse B cell line may be TRAF dependent or independent. European Journal of Immunology. 32: 39-49. PMID 11754002 DOI: 10.1002/1521-4141(200201)32:1<39::Aid-Immu39>3.0.Co;2-Y  0.449
2001 Waldschmidt TJ, Noelle RJ. Immunology: Long live the mature B cell - A baffling mystery resolved Science. 293: 2012-2013. PMID 11557866 DOI: 10.1126/Science.1065591  0.352
2001 Taylor PA, Lees CJ, Waldmann H, Noelle RJ, Blazar BR. Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions. Blood. 98: 467-74. PMID 11435318 DOI: 10.1182/Blood.V98.2.467  0.467
2001 Taylor PA, Noelle RJ, Blazar BR. CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. The Journal of Experimental Medicine. 193: 1311-8. PMID 11390438 DOI: 10.1084/Jem.193.11.1311  0.527
2001 Brams P, Black A, Padlan EA, Hariharan K, Leonard J, Chambers-Slater K, Noelle RJ, Newman R. A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation. International Immunopharmacology. 1: 277-94. PMID 11360929 DOI: 10.1016/S1567-5769(00)00020-5  0.49
2001 Becher B, Durell BG, Miga AV, Hickey WF, Noelle RJ. The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system. The Journal of Experimental Medicine. 193: 967-74. PMID 11304557 DOI: 10.1084/Jem.193.8.967  0.507
2001 Green KA, Noelle RJ, Durell BG, Green WR. Characterization of the CD154-positive and CD40-positive cellular subsets required for pathogenesis in retrovirus-induced murine immunodeficiency. Journal of Virology. 75: 3581-9. PMID 11264347 DOI: 10.1128/Jvi.75.8.3581-3589.2001  0.475
2001 Miga AJ, Masters SR, Durell BG, Gonzalez M, Jenkins MK, Maliszewski C, Kikutani H, Wade WF, Noelle RJ. Dendritic cell longevity and T cell persistence is controlled by CD154-CD40 interactions. European Journal of Immunology. 31: 959-65. PMID 11241301 DOI: 10.1002/1521-4141(200103)31:3<959::Aid-Immu959>3.0.Co;2-A  0.836
2001 Erickson LD, Vogel LA, Cascalho M, Wong J, Wabl M, Durell BG, Noelle RJ. B cell immunopoiesis: visualizing the impact of CD40 engagement on the course of T cell-independent immune responses in an Ig transgenic system. European Journal of Immunology. 30: 3121-31. PMID 11093126 DOI: 10.1002/1521-4141(200011)30:11<3121::Aid-Immu3121>3.0.Co;2-M  0.573
2000 Blazar BR, Lees CJ, Martin PJ, Noelle RJ, Kwon B, Murphy W, Taylor PA. Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions. Journal of Immunology (Baltimore, Md. : 1950). 165: 4901-9. PMID 11046015 DOI: 10.4049/Jimmunol.165.9.4901  0.465
2000 Miga A, Masters S, Gonzalez M, Noelle RJ. The role of CD40-CD154 interactions in the regulation of cell mediated immunity. Immunological Investigations. 29: 111-4. PMID 10854177 DOI: 10.3109/08820130009062292  0.836
2000 Shinall SM, Gonzalez-Fernandez M, Noelle RJ, Waldschmidt TJ. Identification of murine germinal center B cell subsets defined by the expression of surface isotypes and differentiation antigens. Journal of Immunology (Baltimore, Md. : 1950). 164: 5729-38. PMID 10820250 DOI: 10.4049/Jimmunol.164.11.5729  0.451
2000 Schwaab T, Heaney JA, Schned AR, Harris RD, Cole BF, Noelle RJ, Phillips DM, Stempkowski L, Ernstoff MS. A randomized phase II trial comparing two different sequence combinations of autologous vaccine and human recombinant interferon gamma and human recombinant interferon alpha2B therapy in patients with metastatic renal cell carcinoma: clinical outcome and analysis of immunological parameters. The Journal of Urology. 163: 1322-7. PMID 10737537 DOI: 10.1016/S0022-5347(05)67771-3  0.356
2000 Garceau N, Kosaka Y, Masters S, Hambor J, Shinkura R, Honjo T, Noelle RJ. Lineage-restricted function of nuclear factor kappaB-inducing kinase (NIK) in transducing signals via CD40. The Journal of Experimental Medicine. 191: 381-6. PMID 10637282 DOI: 10.1084/Jem.191.2.381  0.661
2000 Taylor PA, Panoskaltsis-Mortari A, Noelle RJ, Blazar BR. Analysis of the requirements for the induction of CD4+ T cell alloantigen hyporesponsiveness by ex vivo anti-CD40 ligand antibody. Journal of Immunology (Baltimore, Md. : 1950). 164: 612-22. PMID 10623802 DOI: 10.4049/Jimmunol.164.2.612  0.531
2000 Calderhead DM, Kosaka Y, Manning EM, Noelle RJ. CD40-CD154 interactions in B-cell signaling. Current Topics in Microbiology and Immunology. 245: 73-99. PMID 10533319  0.602
2000 Fayad RA, Lee H, Noelle R, Barrett T. Ag-nonspecific mechanisms allow for CD40-independent generation of mucosal IgA responses Gastroenterology. 118: A356. DOI: 10.1016/S0016-5085(00)83528-3  0.388
1999 Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA. NOD mice have a generalized defect in their response to transplantation tolerance induction. Diabetes. 48: 967-74. PMID 10331399 DOI: 10.2337/Diabetes.48.5.967  0.391
1999 Kosaka Y, Calderhead DM, Manning EM, Hambor JE, Black A, Geleziunas R, Marcu KB, Noelle RJ. Activation and regulation of the IkappaB kinase in human B cells by CD40 signaling. European Journal of Immunology. 29: 1353-62. PMID 10229103 DOI: 10.1002/(Sici)1521-4141(199904)29:04<1353::Aid-Immu1353>3.0.Co;2-2  0.66
1999 Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Maliszewski C, Mordes JP, Greiner DL, Rossini AA. Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody. Transplantation Proceedings. 31: 884-5. PMID 10083387 DOI: 10.1016/S0041-1345(98)01817-X  0.407
1999 Howard LM, Miga AJ, Vanderlugt CL, Dal Canto MC, Laman JD, Noelle RJ, Miller SD. Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. The Journal of Clinical Investigation. 103: 281-90. PMID 9916140 DOI: 10.1172/Jci5388  0.826
1999 Vogel LA, Noelle RJ. CD40 and its crucial role as a member of the TNFR family. Seminars in Immunology. 10: 435-42. PMID 9826576 DOI: 10.1006/Smim.1998.0145  0.5
1998 Markees T, Phillips N, Gordon E, Noelle RJ, Mordes JP, Greiner DL, Rossini AA. Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody. Transplantation Proceedings. 30: 2444-6. PMID 9723531 DOI: 10.1016/S0041-1345(98)00680-0  0.355
1998 Gordon EJ, Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody. Diabetes. 47: 1199-206. PMID 9703317 DOI: 10.2337/Diab.47.8.1199  0.443
1998 Blazar BR, Taylor PA, Noelle RJ, Vallera DA. CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses. The Journal of Clinical Investigation. 102: 473-82. PMID 9691083 DOI: 10.1172/Jci3741  0.54
1998 Garside P, Ingulli E, Merica RR, Johnson JG, Noelle RJ, Jenkins MK. Visualization of specific B and T lymphocyte interactions in the lymph node. Science (New York, N.Y.). 281: 96-9. PMID 9651253 DOI: 10.1126/Science.281.5373.96  0.516
1998 Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. The Journal of Clinical Investigation. 101: 2446-55. PMID 9616216 DOI: 10.1172/Jci2703  0.441
1998 Mackey MF, Barth RJ, Noelle RJ. The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells. Journal of Leukocyte Biology. 63: 418-28. PMID 9544571 DOI: 10.1002/Jlb.63.4.418  0.555
1998 Gonzalez M, Mackay F, Browning JL, Kosco-Vilbois MH, Noelle RJ. The sequential role of lymphotoxin and B cells in the development of splenic follicles. The Journal of Experimental Medicine. 187: 997-1007. PMID 9529316 DOI: 10.1084/Jem.187.7.997  0.459
1998 Green KA, Noelle RJ, Green WR. Evidence for a continued requirement for CD40/CD40 ligand (CD154) interactions in the progression of LP-BM5 retrovirus-induced murine AIDS. Virology. 241: 260-8. PMID 9499800 DOI: 10.1006/Viro.1997.8970  0.421
1998 Foy TM, McIlraith M, Masters SR, Dunn JJ, Rossini AA, Shultz LD, Hesselton RA, Wagar EJ, Lipsky PE, Noelle RJ, Greiner DL. Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice. Cell Transplantation. 7: 25-35. PMID 9489760 DOI: 10.1016/S0963-6897(97)00113-9  0.535
1998 Noelle RJ. CD40 and its ligand in cell-mediated immunity. Agents and Actions. Supplements. 49: 17-22. PMID 9426824 DOI: 10.1007/978-3-0348-8857-8_4  0.449
1998 Zhou P, Qian L, Bieszczad CK, Noelle R, Binder M, Levy NB, Craig RW. Mcl-1 in Transgenic Mice Promotes Survival in a Spectrum of Hematopoietic Cell Types and Immortalization in the Myeloid Lineage Blood. 92: 3226-3239. DOI: 10.1182/Blood.V92.9.3226.421K49_3226_3239  0.445
1998 Foy TM, Mcilraith M, Masters SR, Dunn JJ, Rossini AA, Shultz LD, Hesselton RAM, Wagar EJ, Lipsky PE, Noelle RJ, Greiner DL. Blockade of Cd40-Cd154 Interferes with Human T cell Engraftment in Scid Mice Cell Transplantation. 7: 25-35. DOI: 10.1177/096368979800700105  0.373
1998 Noelle R. The role of CD40 and its ligand in T cell-mediated autoimmune disease Journal of Neuroimmunology. 90: 8. DOI: 10.1016/S0165-5728(98)91242-5  0.423
1997 Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation. 64: 329-35. PMID 9256196 DOI: 10.1097/00007890-199707270-00026  0.344
1997 Kuhné MR, Robbins M, Hambor JE, Mackey MF, Kosaka Y, Nishimura T, Gigley JP, Noelle RJ, Calderhead DM. Assembly and regulation of the CD40 receptor complex in human B cells. The Journal of Experimental Medicine. 186: 337-42. PMID 9221764 DOI: 10.1084/Jem.186.2.337  0.645
1997 Noelle RJ, Mackey M, Foy T, Buhlmann J, Burns C. CD40 and its ligand in autoimmunity. Annals of the New York Academy of Sciences. 815: 384-91. PMID 9186684 DOI: 10.1111/J.1749-6632.1997.Tb52089.X  0.396
1997 Carayanniotis G, Masters SR, Noelle RJ. Suppression of murine thyroiditis via blockade of the CD40-CD40L interaction. Immunology. 90: 421-6. PMID 9155650 DOI: 10.1111/J.1365-2567.1997.00421.X  0.476
1997 Fang W, Nath KA, Mackey MF, Noelle RJ, Mueller DL, Behrens TW. CD40 inhibits B cell apoptosis by upregulating bcl-x(L) expression and blocking oxidant accumulation American Journal of Physiology - Cell Physiology. 272. PMID 9124531 DOI: 10.1152/Ajpcell.1997.272.3.C950  0.458
1996 Resetkova E, Kawai K, Enomoto T, Arreaza G, Togun R, Foy TM, Noelle RJ, Volpé R. Antibody to gp39, the ligand for CD40 significantly inhibits the humoral response from Graves' thyroid tissues xenografted into severe combined immunodeficient (SCID) mice. Thyroid : Official Journal of the American Thyroid Association. 6: 267-73. PMID 8875745 DOI: 10.1089/Thy.1996.6.267  0.37
1996 Foy TM, Aruffo A, Bajorath J, Buhlmann JE, Noelle RJ. Immune regulation by CD40 and its ligand GP39. Annual Review of Immunology. 14: 591-617. PMID 8717526 DOI: 10.1146/Annurev.Immunol.14.1.591  0.497
1996 Buhlmann JE, Noelle RJ. Therapeutic potential for blockade of the CD40 ligand, gp39. Journal of Clinical Immunology. 16: 83-9. PMID 8690776 DOI: 10.1007/Bf01540954  0.537
1996 Biancone L, Andres G, Ahn H, Lim A, Dai C, Noelle R, Yagita H, De Martino C, Stamenkovic I. Distinct regulatory roles of lymphocyte costimulatory pathways on T helper type-2 mediated autoimmune disease. The Journal of Experimental Medicine. 183: 1473-81. PMID 8666905 DOI: 10.1084/jem.183.4.1473  0.419
1996 Rossini AA, Parker DC, Phillips NE, Durie FH, Noelle RJ, Mordes JP, Greiner DL. Induction of immunological tolerance to islet allografts. Cell Transplantation. 5: 49-52. PMID 8665076 DOI: 10.1016/0963-6897(95)02010-1  0.465
1996 Green KA, Crassi KM, Laman JD, Schoneveld A, Strawbridge RR, Foy TM, Noelle RJ, Green WR. Antibody to the ligand for CD40 (gp39) inhibits murine AIDS-associated splenomegaly, hypergammaglobulinemia, and immunodeficiency in disease-susceptible C57BL/6 mice. Journal of Virology. 70: 2569-75. PMID 8642687 DOI: 10.1128/Jvi.70.4.2569-2575.1996  0.504
1996 Griggs ND, Agersborg SS, Noelle RJ, Ledbetter JA, Linsley PS, Tung KS. The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells. The Journal of Experimental Medicine. 183: 801-10. PMID 8642284 DOI: 10.1084/jem.183.3.801  0.414
1996 Gerritse K, Laman JD, Noelle RJ, Aruffo A, Ledbetter JA, Boersma WJ, Claassen E. CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 93: 2499-504. PMID 8637903 DOI: 10.1073/Pnas.93.6.2499  0.501
1996 Noelle RJ. CD40 and its ligand in host defense. Immunity. 4: 415-9. PMID 8630727 DOI: 10.1016/S1074-7613(00)80408-2  0.379
1996 Sadlack B, Löhler J, Schorle H, Klebb G, Haber H, Sickel E, Noelle RJ, Horak I. Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells. European Journal of Immunology. 25: 3053-9. PMID 7489743 DOI: 10.1002/Eji.1830251111  0.458
1995 Tian L, Noelle RJ, Lawrence DA. Activated T cells enhance nitric oxide production by murine splenic macrophages through gp39 and LFA-1. European Journal of Immunology. 25: 306-9. PMID 7843250 DOI: 10.1002/eji.1830250152  0.344
1995 Gallagher JD, Noelle RJ, McCann FV. Mercury suppression of a potassium current in human B lymphocytes Cellular Signalling. 7: 31-38. PMID 7756108 DOI: 10.1016/0898-6568(93)00065-6  0.313
1995 Foy TM, Page DM, Waldschmidt TJ, Schoneveld A, Laman JD, Masters SR, Tygrett L, Ledbetter JA, Aruffo A, Claassen E, Xu JC, Flavell RA, Oehen S, Hedrick SM, Noelle RJ. An essential role for gp39, the ligand for CD40, in thymic selection. The Journal of Experimental Medicine. 182: 1377-88. PMID 7595208 DOI: 10.1084/Jem.182.5.1377  0.457
1995 Parker DC, Greiner DL, Phillips NE, Appel MC, Steele AW, Durie FH, Noelle RJ, Mordes JP, Rossini AA. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. Proceedings of the National Academy of Sciences of the United States of America. 92: 9560-4. PMID 7568172 DOI: 10.1073/Pnas.92.21.9560  0.45
1995 Noelle RJ. The role of gp39 (CD40L) in immunity. Clinical Immunology and Immunopathology. 76: S203-7. PMID 7554469 DOI: 10.1016/S0090-1229(95)90234-1  0.479
1995 Bajorath J, Marken JS, Chalupny NJ, Spoon TL, Siadak AW, Gordon M, Noelle RJ, Hollenbaugh D, Aruffo A. Analysis of gp39/CD40 interactions using molecular models and site-directed mutagenesis. Biochemistry. 34: 9884-92. PMID 7543281 DOI: 10.1021/Bi00031A009  0.407
1995 Sarma V, Lin Z, Clark L, Rust BM, Tewari M, Noelle RJ, Dixit VM. Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis. The Journal of Biological Chemistry. 270: 12343-6. PMID 7539000 DOI: 10.1074/Jbc.270.21.12343  0.332
1995 van den Eertwegh AJ, Van Meurs M, Foy TM, Noelle RJ, Boersma WJ, Claassen E. In vivo gp39-CD40 interactions occur in the non-follicular compartments of the spleen and are essential for thymus dependent antibody responses and germinal center formation. Advances in Experimental Medicine and Biology. 355: 75-80. PMID 7535976 DOI: 10.1007/978-1-4615-2492-2_13  0.508
1995 Roy M, Aruffo A, Ledbetter J, Linsley P, Kehry M, Noelle R. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. European Journal of Immunology. 25: 596-603. PMID 7533092 DOI: 10.1002/Eji.1830250243  0.482
1995 van den Eertwegh AJ, Laman JD, Noelle RJ, Boersma WJ, Claassen E. In vivo T-B cell interactions and cytokine-production in the spleen. Seminars in Immunology. 6: 327-36. PMID 7532461 DOI: 10.1006/smim.1994.1041  0.449
1995 Foy TM, Durie FH, Noelle RJ. The expansive role of CD40 and its ligand, gp39, in immunity. Seminars in Immunology. 6: 259-66. PMID 7532456 DOI: 10.1006/Smim.1994.1034  0.452
1995 Bajorath J, Chalupny NJ, Marken JS, Siadak AW, Skonier J, Gordon M, Hollenbaugh D, Noelle RJ, Ochs HD, Aruffo A. Identification of residues on CD40 and its ligand which are critical for the receptor-ligand interaction. Biochemistry. 34: 1833-44. PMID 7531493 DOI: 10.1021/Bi00006A003  0.417
1994 Durie FH, Fava RA, Noelle RJ. Collagen-induced arthritis as a model of rheumatoid arthritis. Clinical Immunology and Immunopathology. 73: 11-8. PMID 7923907 DOI: 10.1006/Clin.1994.1164  0.532
1994 Xu J, Foy TM, Laman JD, Elliott EA, Dunn JJ, Waldschmidt TJ, Elsemore J, Noelle RJ, Flavell RA. Mice deficient for the CD40 ligand Immunity. 1: 423-431. PMID 7882172 DOI: 10.1016/1074-7613(94)90073-6  0.351
1994 Laman JD, Claassen E, Noelle RJ. Immunodeficiency due to a faulty interaction between T cells and B cells. Current Opinion in Immunology. 6: 636-41. PMID 7524537 DOI: 10.1016/0952-7915(94)90153-8  0.506
1994 Durie FH, Foy TM, Masters SR, Laman JD, Noelle RJ. The role of CD40 in the regulation of humoral and cell-mediated immunity. Immunology Today. 15: 406-11. PMID 7524518 DOI: 10.1016/0167-5699(94)90269-0  0.585
1994 Durie FH, Aruffo A, Ledbetter J, Crassi KM, Green WR, Fast LD, Noelle RJ. Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease. The Journal of Clinical Investigation. 94: 1333-8. PMID 7521888 DOI: 10.1172/Jci117453  0.433
1994 Hollenbaugh D, Ochs HD, Noelle RJ, Ledbetter JA, Aruffo A. The role of CD40 and its ligand in the regulation of the immune response. Immunological Reviews. 138: 23-37. PMID 7520883 DOI: 10.1111/J.1600-065X.1994.Tb00845.X  0.465
1994 Foy TM, Laman JD, Ledbetter JA, Aruffo A, Claassen E, Noelle RJ. gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. The Journal of Experimental Medicine. 180: 157-63. PMID 7516405 DOI: 10.1084/Jem.180.1.157  0.477
1994 Farrington M, Grosmaire LS, Nonoyama S, Fischer SH, Hollenbaugh D, Ledbetter JA, Noelle RJ, Aruffo A, Ochs HD. CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency Proceedings of the National Academy of Sciences of the United States of America. 91: 1099-1103. PMID 7508119 DOI: 10.1073/pnas.91.3.1099  0.342
1994 Noelle RJ. Introduction: CD40, its ligand and immunity Seminars in Immunology. 6: 257. DOI: 10.1006/Smim.1994.1033  0.45
1993 McCarthy DC, Noelle RJ, Gallagher JD, McCann FV. Effects of cadmium on potassium currents in activated B lymphocytes Cellular Signalling. 5: 417-424. PMID 8373723 DOI: 10.1016/0898-6568(93)90081-V  0.342
1993 Foy TM, Shepherd DM, Durie FH, Aruffo A, Ledbetter JA, Noelle RJ. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39 Journal of Experimental Medicine. 178: 1567-1575. PMID 7693850 DOI: 10.1084/Jem.178.5.1567  0.502
1993 Van Den Eertwegh AJM, Noelle RJ, Roy M, Shepherd DM, Aruffo A, Ledbetter JA, Boersma WJA, Claassen E. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions Journal of Experimental Medicine. 178: 1555-1565. PMID 7693849 DOI: 10.1084/jem.178.5.1555  0.423
1993 Durie FH, Fava RA, Foy TM, Aruffo A, Ledbetter JA, Noelle RJ. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40 Science. 261: 1328-1330. PMID 7689748 DOI: 10.1126/Science.7689748  0.448
1993 Marshall LS, Aruffo A, Ledbetter JA, Noelle RJ. The molecular basis for T cell help in humoral immunity: CD40 and its ligand, gp39 Journal of Clinical Immunology. 13: 165-174. PMID 7686564 DOI: 10.1007/Bf00919969  0.517
1993 Daum JR, Shepherd DM, Noelle RJ. Immunotoxicology of cadmium and mercury on B-lymphocytes--I. Effects on lymphocyte function. International Journal of Immunopharmacology. 15: 383-94. PMID 7685007 DOI: 10.1016/0192-0561(93)90049-5  0.386
1993 Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, Nonoyama S, Bajorath J, Grosmaire LS, Stenkamp R, Neubauer M, Roberts RL, Noelle RJ, Ledbetter JA, Francke U, Ochs HD. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome Cell. 72: 291-300. PMID 7678782 DOI: 10.1016/0092-8674(93)90668-G  0.428
1993 Noelle RJ, Ledbetter JA, Aruffo A. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunology Today. 13: 431-3. PMID 1282319 DOI: 10.1016/0167-5699(92)90068-I  0.486
1992 McCann FV, McCarthy DC, Noelle RJ. Interleukin-4 activates ion channels in B lymphocytes. Cellular Signalling. 3: 483-90. PMID 1722108 DOI: 10.1016/0898-6568(91)90078-9  0.329
1992 Noelle R, Snow EC. T helper cells. Current Opinion in Immunology. 4: 333-7. PMID 1418713 DOI: 10.1016/0952-7915(92)90085-S  0.426
1992 Noelle RJ, Roy M, Shepherd DM, Stamenkovic I, Ledbetter JA, Aruffo A. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 6550-4. PMID 1378631 DOI: 10.1073/Pnas.89.14.6550  0.511
1992 Noelle RJ, Marshall L, Roy M, Shepherd DM, Stamenkovic I, Ledbetter JA, Aruffo A, Fell HP. Role of contact and soluble factors in the growth and differentiation of B cells by helper T cells Advances in Experimental Medicine and Biology. 323: 131-138. PMID 1283047 DOI: 10.1007/978-1-4615-3396-2_17  0.342
1992 Hollenbaugh D, Grosmaire L, Kullas C, Chalupny N, Braesch-Andersen S, Noelle R, Stamenkovic I, Ledbetter J, Aruffo A. The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity. The Embo Journal. 11: 4313-4321. DOI: 10.1002/j.1460-2075.1992.tb05530.x  0.359
1991 Shepherd DM, Noelle RJ. The lack of memory B cells in immune bone marrow. Transplantation. 52: 97-100. PMID 1858161 DOI: 10.1097/00007890-199107000-00020  0.415
1991 Noelle RJ, Snow EC. T helper cell-dependent B cell activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2770-6. PMID 1833257 DOI: 10.1096/fasebj.5.13.1833257  0.392
1990 Marshall LS, Noelle RJ. Contact-dependent B-cell activation by helper T cells Research in Immunology. 141: 412-417. PMID 2148424 DOI: 10.1016/0923-2494(90)90031-S  0.361
1990 Noelle RJ, Snow EC. Cognate interactions between helper T cells and B cells. Immunology Today. 11: 361-8. PMID 2145852 DOI: 10.1016/0167-5699(90)90142-V  0.492
1989 Albrecht DL, Noelle RJ. Membrane immunoglobulin-cytoskeletal interactions-II. Biochemical analysis of cytoskeletally associated IgM Molecular Immunology. 26: 575-582. PMID 2788805 DOI: 10.1016/0161-5890(89)90009-6  0.407
1988 Snow EC, Noelle RJ. Thymus-dependent antigenic stimulation of hapten-specific B lymphocytes. Immunological Reviews. 99: 173-92. PMID 2445657 DOI: 10.1111/J.1600-065X.1987.Tb01177.X  0.348
1987 Bartlett WC, Noelle RJ. A cell surface ELISA to detect interleukin-4-induced class II MHC expression on murine B cells Journal of Immunological Methods. 105: 79-85. PMID 3119727 DOI: 10.1016/0022-1759(87)90416-9  0.398
1985 Oliver K, Noelle RJ, Uhr JW, Krammer PH, Vitetta ES. B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth. Proceedings of the National Academy of Sciences of the United States of America. 82: 2465-7. PMID 3873068 DOI: 10.1073/pnas.82.8.2465  0.312
1984 Noelle R, Krammer PH, Ohara J, Uhr JW, Vitetta ES. Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor. Proceedings of the National Academy of Sciences of the United States of America. 81: 6149-53. PMID 6435125 DOI: 10.1073/pnas.81.19.6149  0.333
1983 Noelle RJ, Snow EC, Uhr JW, Vitetta ES. Activation of antigen-specific B cells: role of T cells, cytokines, and antigen in induction of growth and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 80: 6628-31. PMID 6605533 DOI: 10.1073/pnas.80.21.6628  0.408
1981 Noelle RJ, Lawrence DA. Modulation of T-cell function. II. Chemical basis for the involvement of cell surface thiol-reactive sites in control of T-cell proliferation. Cellular Immunology. 60: 453-69. PMID 6972270 DOI: 10.1016/0008-8749(81)90286-0  0.333
1980 Noelle RJ, Lawrence DA. Modulation of T-cell functions. I. Effect of 2-mercaptoethanol and macrophages on T-cell proliferation. Cellular Immunology. 50: 416-31. PMID 6965617 DOI: 10.1016/0008-8749(80)90295-6  0.355
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