Year |
Citation |
Score |
2020 |
Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design. Science Advances. 6. PMID 33067239 DOI: 10.1126/sciadv.abd4596 |
0.315 |
|
2020 |
Rut W, Zmudzinski M, Snipas SJ, Bekes M, Huang TT, Drag M. Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes. Chemical Science. 11: 6058-6069. PMID 32953009 DOI: 10.1039/D0Sc01347A |
0.44 |
|
2020 |
Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design. Biorxiv : the Preprint Server For Biology. PMID 32511411 DOI: 10.1101/2020.04.29.068890 |
0.329 |
|
2018 |
Suisse A, Békés M, Huang TT, Treisman JE. The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity. Fly. 0. PMID 29355077 DOI: 10.1080/19336934.2018.1429858 |
0.398 |
|
2017 |
Coleman KE, Békés M, Chapman JR, Crist SB, Jones MJ, Ueberheide BM, Huang TT. SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function. Elife. 6. PMID 28475037 DOI: 10.7554/Elife.24325 |
0.442 |
|
2016 |
Békés M, van der Heden van Noort GJ, Ekkebus R, Ovaa H, Huang TT, Lima CD. Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease. Molecular Cell. 62: 572-585. PMID 27203180 DOI: 10.1016/J.Molcel.2016.04.016 |
0.39 |
|
2016 |
Bekes M, Ekkebus R, Noort GJvdHv, Ovaa H, Huang TT, Lima CD. Structural basis for the diUb-Lys48 recognition and specificity of the SARS coronavirus deubiquitinating enzyme, SARS PLpro Molecular Cell. 62. DOI: 10.2210/Pdb5E6J/Pdb |
0.347 |
|
2015 |
Békés M, Rut W, Kasperkiewicz P, Mulder MP, Ovaa H, Drag M, Lima CD, Huang TT. SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme. The Biochemical Journal. 468: 215-26. PMID 25764917 DOI: 10.1042/Bj20141170 |
0.418 |
|
2012 |
Cotto-Rios XM, Békés M, Chapman J, Ueberheide B, Huang TT. Deubiquitinases as a signaling target of oxidative stress. Cell Reports. 2: 1475-84. PMID 23219552 DOI: 10.1016/J.Celrep.2012.11.011 |
0.337 |
|
2012 |
Békés M, Drag M. Trojan horse strategies used by pathogens to influence the small ubiquitin-like modifier (SUMO) system of host eukaryotic cells. Journal of Innate Immunity. 4: 159-67. PMID 22223032 DOI: 10.1159/000335027 |
0.32 |
|
2011 |
Albrow VE, Ponder EL, Fasci D, Békés M, Deu E, Salvesen GS, Bogyo M. Development of small molecule inhibitors and probes of human SUMO deconjugating proteases. Chemistry & Biology. 18: 722-32. PMID 21700208 DOI: 10.1016/J.Chembiol.2011.05.008 |
0.393 |
|
2011 |
Ponder EL, Albrow VE, Leader BA, Békés M, Mikolajczyk J, Fonović UP, Shen A, Drag M, Xiao J, Deu E, Campbell AJ, Powers JC, Salvesen GS, Bogyo M. Functional characterization of a SUMO deconjugating protease of Plasmodium falciparum using newly identified small molecule inhibitors. Chemistry & Biology. 18: 711-21. PMID 21700207 DOI: 10.1016/J.Chembiol.2011.04.010 |
0.423 |
|
2010 |
Shu CW, Drag M, Bekes M, Zhai D, Salvesen GS, Reed JC. Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4). Autophagy. 6: 936-47. PMID 20818167 DOI: 10.4161/Auto.6.7.13075 |
0.44 |
|
2009 |
Zhu S, Goeres J, Sixt KM, Békés M, Zhang XD, Salvesen GS, Matunis MJ. Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1. Molecular Cell. 33: 570-80. PMID 19285941 DOI: 10.1016/J.Molcel.2009.02.008 |
0.346 |
|
2008 |
Drag M, Mikolajczyk J, Bekes M, Reyes-Turcu FE, Ellman JA, Wilkinson KD, Salvesen GS. Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes). The Biochemical Journal. 415: 367-75. PMID 18601651 DOI: 10.1042/Bj20080779 |
0.438 |
|
2007 |
Mikolajczyk J, Drag M, Békés M, Cao JT, Ronai Z, Salvesen GS. Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs. The Journal of Biological Chemistry. 282: 26217-24. PMID 17591783 DOI: 10.1074/Jbc.M702444200 |
0.478 |
|
2006 |
Denault JB, Békés M, Scott FL, Sexton KM, Bogyo M, Salvesen GS. Engineered hybrid dimers: tracking the activation pathway of caspase-7. Molecular Cell. 23: 523-33. PMID 16916640 DOI: 10.1016/J.Molcel.2006.06.020 |
0.345 |
|
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