Gary E. Shull - Publications

Affiliations: 
Molecular Genetics, Biochemistry, & Microbiology University of Cincinnati, Cincinnati, OH 
Area:
Physiology Biology, Molecular Biology, Bioinformatics Biology

179 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhao W, Ermilov L, Mazzone A, Silva JM, Eisenman ST, Aguilar MGC, Shull GE, Romero MF, Sha L, Farrugia G, Gibbons SJ. Sa1122 – The Electrogenic Na+/HCO3- CO-Transporter (NBCE1/SLC4A4) is Necessary FOR Normal Electrical Slow Wave Activity in the Mouse Small Intestine Gastroenterology. 156: S-276. DOI: 10.1016/S0016-5085(19)37505-5  0.365
2018 Song S, Wang S, Pigott VM, Jiang T, Foley LM, Mishra A, Nayak R, Zhu W, Begum G, Shi Y, Carney KE, Hitchens TK, Shull GE, Sun D. Selective role of Na /H exchanger in Cx3cr1 microglial activation, white matter demyelination, and post-stroke function recovery. Glia. PMID 30043461 DOI: 10.1002/Glia.23456  0.338
2018 Mukaibo T, Munemasa T, George AT, Tran DT, Gao X, Herche J, Masaki C, Shull GE, Soleimani M, Melvin JE. The apical anion exchanger Slc26a6 promotes oxalate secretion by murine submandibular gland acinar cells. The Journal of Biological Chemistry. PMID 29530983 DOI: 10.1074/Jbc.Ra118.002378  0.489
2017 Begum G, Song S, Wang S, Zhao H, Bhuiyan MIH, Li E, Nepomuceno R, Ye Q, Sun M, Calderon MJ, Stolz DB, St Croix C, Watkins SC, Chen Y, He P, ... Shull GE, et al. Selective knockout of astrocytic Na(+) /H(+) exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke. Glia. PMID 28925083 DOI: 10.1002/Glia.23232  0.363
2017 Vairamani K, Wang HS, Medvedovic M, Lorenz JN, Shull GE. RNA SEQ Analysis Indicates that the AE3 Cl(-)/HCO3(-) Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart. Scientific Reports. 7: 7264. PMID 28779178 DOI: 10.1038/S41598-017-07585-Y  0.357
2017 Fleming SM, Santiago NA, Mullin EJ, Pamphile S, Karkare S, Lemkuhl A, Ekhator OR, Linn SC, Holden JG, Aga DS, Roth JA, Liou B, Sun Y, Shull GE, Schultheis PJ. The Effect of Manganese Exposure in Atp13a2-deficient Mice. Neurotoxicology. PMID 28595912 DOI: 10.1016/J.Neuro.2017.06.005  0.415
2016 Urso K, Charles JF, Shull GE, Aliprantis AO, Balestrieri B. Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans. Plos One. 11: e0158893. PMID 27391897 DOI: 10.1371/Journal.Pone.0158893  0.376
2016 Shawki A, Engevik MA, Kim RS, Knight PB, Baik RA, Anthony SR, Worrell RT, Shull GE, Mackenzie B. Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00167.2016. PMID 27390324 DOI: 10.1152/Ajpgi.00167.2016  0.38
2016 Yu Q, Liu X, Liu Y, Riederer B, Li T, Tian DA, Tuo B, Shull G, Seidler U. Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice. Pflugers Archiv : European Journal of Physiology. PMID 27228994 DOI: 10.1007/S00424-016-1836-3  0.484
2016 Peña-Münzenmayer G, George AT, Shull GE, Melvin JE, Catalán MA. Ae4 (Slc4a9) is an electroneutral monovalent cation-dependent Cl-/HCO3- exchanger. The Journal of General Physiology. 147: 423-36. PMID 27114614 DOI: 10.1085/Jgp.201611571  0.436
2016 Bradford EM, Vairamani K, Shull GE. Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine. World Journal of Gastrointestinal Pathophysiology. 7: 138-49. PMID 26909237 DOI: 10.4291/Wjgp.V7.I1.138  0.706
2015 Li XC, Shull GE, Miguel-Qin E, Chen F, Zhuo JL. Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines. Physiological Reports. 3. PMID 26564064 DOI: 10.14814/Phy2.12605  0.444
2015 Nighot MP, Nighot PK, Ma TY, Malinowska DH, Shull GE, Cuppoletti J, Blikslager AT. Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion. Plos One. 10: e0138174. PMID 26378782 DOI: 10.1371/Journal.Pone.0138174  0.424
2015 Li XC, Shull GE, Miguel-Qin E, Zhuo JL. Role of the Na+/H+ Exchanger 3 in Angiotensin II-Induced Hypertension. Physiological Genomics. physiolgenomics.0005. PMID 26242933 DOI: 10.1152/Physiolgenomics.00056.2015  0.407
2015 Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, ... ... Shull GE, et al. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Nature Medicine. 21: 820-6. PMID 26099046 DOI: 10.1038/Nm.3890  0.378
2015 Prasad V, Lorenz JN, Lasko VM, Nieman ML, Huang W, Wang Y, Wieczorek DW, Shull GE. SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure. Biomed Research International. 2015: 251598. PMID 26064889 DOI: 10.1155/2015/251598  0.337
2015 Peña-Münzenmayer G, Catalán MA, Kondo Y, Jaramillo Y, Liu F, Shull GE, Melvin JE. Ae4 (Slc4a9) Anion Exchanger Drives Cl- Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells. The Journal of Biological Chemistry. 290: 10677-88. PMID 25745107 DOI: 10.1074/Jbc.M114.612895  0.536
2015 Catalán MA, Kondo Y, Peña-Munzenmayer G, Jaramillo Y, Liu F, Choi S, Crandall E, Borok Z, Flodby P, Shull GE, Melvin JE. A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland. Proceedings of the National Academy of Sciences of the United States of America. 112: 2263-8. PMID 25646474 DOI: 10.1073/Pnas.1415739112  0.449
2014 Prasad V, Lorenz JN, Lasko VM, Nieman ML, Jiang M, Gao X, Rubinstein J, Wieczorek DF, Shull GE. Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 77: 53-63. PMID 25280781 DOI: 10.1016/J.Yjmcc.2014.09.025  0.426
2014 Wang HS, Chen Y, Vairamani K, Shull GE. Critical role of bicarbonate and bicarbonate transporters in cardiac function. World Journal of Biological Chemistry. 5: 334-45. PMID 25225601 DOI: 10.4331/Wjbc.V5.I3.334  0.396
2014 Prasad V, Chirra S, Kohli R, Shull GE. NHE1 deficiency in liver: implications for non-alcoholic fatty liver disease. Biochemical and Biophysical Research Communications. 450: 1027-31. PMID 24976401 DOI: 10.1016/J.Bbrc.2014.06.095  0.304
2014 Theparambil SM, Ruminot I, Schneider HP, Shull GE, Deitmer JW. The electrogenic sodium bicarbonate cotransporter NBCe1 is a high-affinity bicarbonate carrier in cortical astrocytes Journal of Neuroscience. 34: 1148-1157. PMID 24453308 DOI: 10.1523/Jneurosci.2377-13.2014  0.392
2013 Engevik MA, Hickerson A, Shull GE, Worrell RT. Acidic conditions in the NHE2(-/-) mouse intestine result in an altered mucosa-associated bacterial population with changes in mucus oligosaccharides. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 32: 111-28. PMID 24429819 DOI: 10.1159/000356632  0.351
2013 Prasad V, Lorenz JN, Lasko VM, Nieman ML, Al Moamen NJ, Shull GE. Loss of the AE3 Cl(-)/HCO(-) 3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart. Frontiers in Physiology. 4: 399. PMID 24427143 DOI: 10.3389/Fphys.2013.00399  0.408
2013 Aihara E, Hentz CL, Korman AM, Perry NPJ, Prasad V, Shull GE, Montrose MH. In vivo epithelial wound repair requires mobilization of endogenous intracellular and extracellular calcium Journal of Biological Chemistry. 288: 33585-33597. PMID 24121509 DOI: 10.1074/Jbc.M113.488098  0.372
2013 Prasad V, Lorenz JN, Miller ML, Vairamani K, Nieman ML, Wang Y, Shull GE. Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress. Journal of Molecular and Cellular Cardiology. 65: 33-42. PMID 24080184 DOI: 10.1016/J.Yjmcc.2013.09.013  0.372
2013 Engevik MA, Aihara E, Montrose MH, Shull GE, Hassett DJ, Worrell RT. Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G697-711. PMID 24072680 DOI: 10.1152/Ajpgi.00184.2013  0.381
2013 Schultheis PJ, Fleming SM, Clippinger AK, Lewis J, Tsunemi T, Giasson B, Dickson DW, Mazzulli JR, Bardgett ME, Haik KL, Ekhator O, Chava AK, Howard J, Gannon M, Hoffman E, ... ... Shull GE, et al. Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits. Human Molecular Genetics. 22: 2067-82. PMID 23393156 DOI: 10.1093/Hmg/Ddt057  0.38
2013 Coury F, Zenger S, Stewart AK, Stephens S, Neff L, Tsang K, Shull GE, Alper SL, Baron R, Aliprantis AO. SLC4A2-mediated Cl-/HCO3- exchange activity is essential for calpain-dependent regulation of the actin cytoskeleton in osteoclasts. Proceedings of the National Academy of Sciences of the United States of America. 110: 2163-8. PMID 23341620 DOI: 10.1073/Pnas.1206392110  0.366
2013 Yu Q, Liu X, Riederer B, Tian D, Tuo B, Shull G, Seidler U. Sa1946 Role of the Electrogenic Na+HCO3- Cotransporter NBCe1 in PHI Regulation and Anion Secretion in Murine Intestine Gastroenterology. 144: S-341. DOI: 10.1016/S0016-5085(13)61255-X  0.434
2013 Engevik MA, Shull G, Worrell RT. 889 NHE2−/− Mice Have Altered Intestinal Microbiota and Epithelia Oligosaccharide Patterns Gastroenterology. 144: S-157. DOI: 10.1016/S0016-5085(13)60564-8  0.406
2012 Soleimani M, Barone S, Xu J, Shull GE, Siddiqui F, Zahedi K, Amlal H. Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure. Proceedings of the National Academy of Sciences of the United States of America. 109: 13368-73. PMID 22847418 DOI: 10.1073/Pnas.1202671109  0.468
2012 Chen M, Praetorius J, Zheng W, Xiao F, Riederer B, Singh AK, Stieger N, Wang J, Shull GE, Aalkjaer C, Seidler U. The electroneutral Na⁺:HCO₃⁻ cotransporter NBCn1 is a major pHi regulator in murine duodenum. The Journal of Physiology. 590: 3317-33. PMID 22586225 DOI: 10.1113/Jphysiol.2011.226506  0.355
2012 Pan W, Borovac J, Spicer Z, Hoenderop JG, Bindels RJ, Shull GE, Doschak MR, Cordat E, Alexander RT. The epithelial sodium/proton exchanger, NHE3, is necessary for renal and intestinal calcium (re)absorption. American Journal of Physiology. Renal Physiology. 302: F943-56. PMID 21937605 DOI: 10.1152/Ajprenal.00504.2010  0.772
2011 Ruminot I, Gutiérrez R, Peña-Münzenmayer G, Añazco C, Sotelo-Hitschfeld T, Lerchundi R, Niemeyer MI, Shull GE, Barros LF. NBCe1 mediates the acute stimulation of astrocytic glycolysis by extracellular K+. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14264-71. PMID 21976511 DOI: 10.1523/Jneurosci.2310-11.2011  0.4
2011 Shull GE, Miller ML, Prasad V. Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction. Biofactors (Oxford, England). 37: 150-8. PMID 21674634 DOI: 10.1002/Biof.141  0.382
2011 Miller ML, Andringa A, Schultheis PJ, Shull GE. Loss of the NHE2 Na+/H+ exchanger in mice results in dilation of folliculo-stellate cell canaliculi. Journal of Biomedicine & Biotechnology. 2011: 510827. PMID 21274460 DOI: 10.1155/2011/510827  0.505
2011 Al Moamen NJ, Prasad V, Bodi I, Miller ML, Neiman ML, Lasko VM, Alper SL, Wieczorek DF, Lorenz JN, Shull GE. Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. Journal of Molecular and Cellular Cardiology. 50: 137-46. PMID 21056571 DOI: 10.1016/J.Yjmcc.2010.10.028  0.36
2011 Leviel F, Hübner CA, Houillier P, Morla L, El Moghrabi S, Brideau G, Hassan H, Parker MD, Kurth I, Kougioumtzes A, Sinning A, Pech V, Riemondy KA, Miller RL, Hummler E, ... Shull GE, et al. The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice Journal of Clinical Investigation. 121: 1668-1668. DOI: 10.1172/Jci57722  0.474
2010 Shao J, Gumz ML, Cain BD, Xia SL, Shull GE, van Driel IR, Wingo CS. Pharmacological profiles of the murine gastric and colonic H,K-ATPases. Biochimica Et Biophysica Acta. 1800: 906-11. PMID 20594946 DOI: 10.1016/J.Bbagen.2010.05.002  0.386
2010 Liu Y, Kintner DB, Begum G, Algharabli J, Cengiz P, Shull GE, Liu XJ, Sun D. Endoplasmic reticulum Ca2+ signaling and mitochondrial Cyt c release in astrocytes following oxygen and glucose deprivation. Journal of Neurochemistry. 114: 1436-46. PMID 20557423 DOI: 10.1111/J.1471-4159.2010.06862.X  0.312
2010 Bourgeois S, Meer LV, Wootla B, Bloch-Faure M, Chambrey R, Shull GE, Gawenis LR, Houillier P. NHE4 is critical for the renal handling of ammonia in rodents. The Journal of Clinical Investigation. 120: 1895-904. PMID 20484819 DOI: 10.1172/Jci36581  0.462
2010 Leviel F, Hübner CA, Houillier P, Morla L, El Moghrabi S, Brideau G, Hassan H, Hatim H, Parker MD, Kurth I, Kougioumtzes A, Sinning A, Pech V, Riemondy KA, Miller RL, ... ... Shull GE, et al. The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. The Journal of Clinical Investigation. 120: 1627-35. PMID 20389022 DOI: 10.1172/Jci40145  0.49
2010 Bradford EM, Miller ML, Prasad V, Nieman ML, Gawenis LR, Berryman M, Lorenz JN, Tso P, Shull GE. CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R1531-42. PMID 20357015 DOI: 10.1152/Ajpregu.00849.2009  0.732
2010 Miller ML, Andringa A, Zavros Y, Bradford EM, Shull GE. Volume density, distribution, and ultrastructure of secretory and basolateral membranes and mitochondria predict parietal cell secretory (dys)function. Journal of Biomedicine & Biotechnology. 2010: 394198. PMID 20339514 DOI: 10.1155/2010/394198  0.754
2010 Gawenis LR, Bradford EM, Alper SL, Prasad V, Shull GE. AE2 Cl-/HCO3- exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G493-503. PMID 20110461 DOI: 10.1152/Ajpgi.00178.2009  0.749
2010 Chen X, Kintner DB, Baba A, Matsuda T, Shull GE, Sun D. Protein aggregation in neurons following OGD: a role for Na+ and Ca2+ ionic dysregulation. Journal of Neurochemistry. 112: 173-82. PMID 19840218 DOI: 10.1111/J.1471-4159.2009.06438.X  0.359
2009 Sinkins WG, Estacion M, Prasad V, Goel M, Shull GE, Kunze DL, Schilling WP. Maitotoxin converts the plasmalemmal Ca(2+) pump into a Ca(2+)-permeable nonselective cation channel. American Journal of Physiology. Cell Physiology. 297: C1533-43. PMID 19794142 DOI: 10.1152/Ajpcell.00252.2009  0.378
2009 Yu H, Riederer B, Stieger N, Boron WF, Shull GE, Manns MP, Seidler UE, Bachmann O. Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G1223-31. PMID 19779011 DOI: 10.1152/Ajpgi.00157.2009  0.405
2009 Wu X, Chang B, Blair NS, Sargent M, York AJ, Robbins J, Shull GE, Molkentin JD. Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents. The Journal of Clinical Investigation. 119: 976-85. PMID 19287093 DOI: 10.1172/Jci36693  0.384
2009 Bradford EM, Sartor MA, Gawenis LR, Clarke LL, Shull GE. Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G886-98. PMID 19164484 DOI: 10.1152/Ajpgi.90520.2008  0.759
2009 Yu H, Riederer B, Stieger N, Boron W, Shull G, Manns M, Seidler U, Bachmann O. Sekretagoga-Stimulation steigert die NBCe1 (elektrogener Na+/HCO3--Kotransporter) Membranexpression in Kolonkrypten der Maus Zeitschrift Fur Gastroenterologie. 47: 32. DOI: 10.1055/S-0029-1241283  0.348
2009 Song P, Feng Z, Riederer B, Krabbenhöft A, Rausch B, Anstätt M, Bantel H, Lamlé J, Vogel A, Soleimani M, Shull GE, Miller ML, Seidler U. 788 Effect of Genetic Ablation of the Acid/Base Transporters PNBC1, NHE1, NHE2, and Slc26a7, On Gastric Epithelial Functions Gastroenterology. 136: A-125. DOI: 10.1016/S0016-5085(09)60558-8  0.537
2008 Xu J, Song P, Miller ML, Borgese F, Barone S, Riederer B, Wang Z, Alper SL, Forte JG, Shull GE, Ehrenfeld J, Seidler U, Soleimani M. Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach. Proceedings of the National Academy of Sciences of the United States of America. 105: 17955-60. PMID 19004773 DOI: 10.1073/Pnas.0800616105  0.515
2008 Prasad V, Bodi I, Meyer JW, Wang Y, Ashraf M, Engle SJ, Doetschman T, Sisco K, Nieman ML, Miller ML, Lorenz JN, Shull GE. Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases. The Journal of Biological Chemistry. 283: 31303-14. PMID 18779325 DOI: 10.1074/Jbc.M803706200  0.447
2008 Hanner F, Chambrey R, Bourgeois S, Meer E, Mucsi I, Rosivall L, Shull GE, Lorenz JN, Eladari D, Peti-Peterdi J. Increased renal renin content in mice lacking the Na+/H+ exchanger NHE2. American Journal of Physiology. Renal Physiology. 294: F937-44. PMID 18287398 DOI: 10.1152/Ajprenal.00591.2007  0.516
2008 Lynch IJ, Rudin A, Xia SL, Stow LR, Shull GE, Weiner ID, Cain BD, Wingo CS. Impaired acid secretion in cortical collecting duct intercalated cells from H-K-ATPase-deficient mice: role of HKalpha isoforms. American Journal of Physiology. Renal Physiology. 294: F621-7. PMID 18057185 DOI: 10.1152/Ajprenal.00412.2007  0.484
2008 Luo J, Wang Y, Chen H, Kintner DB, Cramer SW, Gerdts JK, Chen X, Shull GE, Philipson KD, Sun D. A concerted role of Na+ -K+ -Cl- cotransporter and Na+/Ca2+ exchanger in ischemic damage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 737-46. PMID 17912271 DOI: 10.1038/Sj.Jcbfm.9600561  0.369
2008 Bradford EM, Gawenis L, Clarke LL, Shull G. Reduced Absorption Counters the Cystic Fibrosis Intestinal Phenotype and Increases Survival The Faseb Journal. 22: 138-138. DOI: 10.1096/Fasebj.22.2_Supplement.138  0.687
2008 Bradford E, Shull G, Miller M. The Ghost of the IEL: A Halloween Photoshop Exercise Microscopy Today. 16: 75-75. DOI: 10.1017/S1551929500062465  0.719
2008 Xu J, Ehrenfeld J, Miller ML, Wang Z, Barone S, Alper S, Shull GE, Forte JG, Borgese F, Soleimani M. 209 Deletion of the Chloride Transporter Slc26a9 Causes Loss of Tubulovesicles in Gastric Parietal Cells and Impairs Acid Secretion Gastroenterology. 134: A-36-A-37. DOI: 10.1016/S0016-5085(08)60177-8  0.373
2007 Alvarez BV, Gilmour GS, Mema SC, Martin BT, Shull GE, Casey JR, Sauvé Y. Blindness caused by deficiency in AE3 chloride/bicarbonate exchanger. Plos One. 2: e839. PMID 17786210 DOI: 10.1371/Journal.Pone.0000839  0.385
2007 Diaz RC, Vazquez AE, Dou H, Wei D, Cardell EL, Lingrel J, Shull GE, Doyle KJ, Yamoah EN. Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1. Journal of the Association For Research in Otolaryngology : Jaro. 8: 422-34. PMID 17674100 DOI: 10.1007/S10162-007-0089-4  0.377
2007 Okunade GW, Miller ML, Azhar M, Andringa A, Sanford LP, Doetschman T, Prasad V, Shull GE. Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes. The Journal of Biological Chemistry. 282: 26517-27. PMID 17597066 DOI: 10.1074/Jbc.M703029200  0.417
2007 Luo J, Wang Y, Chen X, Chen H, Kintner DB, Shull GE, Philipson KD, Sun D. Increased tolerance to ischemic neuronal damage by knockdown of Na+-Ca2+ exchanger isoform 1. Annals of the New York Academy of Sciences. 1099: 292-305. PMID 17446470 DOI: 10.1196/Annals.1387.016  0.422
2007 Prasad V, Okunade G, Liu L, Paul RJ, Shull GE. Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice. Annals of the New York Academy of Sciences. 1099: 276-86. PMID 17446468 DOI: 10.1196/Annals.1387.029  0.403
2007 Gawenis LR, Bradford EM, Prasad V, Lorenz JN, Simpson JE, Clarke LL, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter. The Journal of Biological Chemistry. 282: 9042-52. PMID 17192275 DOI: 10.1074/Jbc.M607041200  0.783
2007 Simpson JE, Schweinfest CW, Shull GE, Gawenis LR, Walker NM, Boyle KT, Soleimani M, Clarke LL. PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1079-88. PMID 17170027 DOI: 10.1152/Ajpgi.00354.2006  0.471
2007 Kintner DB, Luo J, Gerdts J, Ballard AJ, Shull GE, Sun D. Role of Na+-K+-Cl- cotransport and Na+/Ca2+ exchange in mitochondrial dysfunction in astrocytes following in vitro ischemia. American Journal of Physiology. Cell Physiology. 292: C1113-22. PMID 17035299 DOI: 10.1152/Ajpcell.00412.2006  0.343
2007 Liu L, Ishida Y, Okunade G, Pyne-Geithman GJ, Shull GE, Paul RJ. Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice. American Journal of Physiology. Cell Physiology. 292: C423-31. PMID 16956963 DOI: 10.1152/Ajpcell.00313.2006  0.344
2006 Lorenz JN, Dostanic-Larson I, Shull GE, Lingrel JB. Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase. Journal of the American Society of Nephrology : Jasn. 17: 2457-63. PMID 16870707 DOI: 10.1681/Asn.2006040379  0.437
2006 Guan Y, Dong J, Tackett L, Meyer JW, Shull GE, Montrose MH. NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G689-99. PMID 16690903 DOI: 10.1152/Ajpgi.00342.2005  0.477
2006 Luo J, Chen H, Kintner DB, Shull GE, Sun D. Inhibition of Na+/H+ exchanger isoform 1 attenuates mitochondrial cytochrome C release in cortical neurons following in vitro ischemia. Acta Neurochirurgica. Supplement. 96: 244-8. PMID 16671463 DOI: 10.1007/3-211-30714-1_52  0.374
2006 Pestov NB, Korneenko TV, Shakhparonov MI, Shull GE, Modyanov NN. Loss of acidification of anterior prostate fluids in Atp12a-null mutant mice indicates that nongastric H-K-ATPase functions as proton pump in vivo. American Journal of Physiology. Cell Physiology. 291: C366-74. PMID 16525125 DOI: 10.1152/Ajpcell.00042.2006  0.409
2006 Liu L, Ishida Y, Okunade G, Shull GE, Paul RJ. Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice. American Journal of Physiology. Cell Physiology. 290: C1239-47. PMID 16291816 DOI: 10.1152/Ajpcell.00440.2005  0.378
2006 Wall SM, Knepper MA, Hassell KA, Fischer MP, Shodeinde A, Shin W, Pham TD, Meyer JW, Lorenz JN, Beierwaltes WH, Dietz JR, Shull GE, Kim YH. Hypotension in NKCC1 null mice: role of the kidneys. American Journal of Physiology. Renal Physiology. 290: F409-16. PMID 16159893 DOI: 10.1152/Ajprenal.00309.2005  0.526
2005 Luo J, Chen H, Kintner DB, Shull GE, Sun D. Decreased neuronal death in Na+/H+ exchanger isoform 1-null mice after in vitro and in vivo ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11256-68. PMID 16339021 DOI: 10.1523/Jneurosci.3271-05.2005  0.444
2005 Prasad V, Boivin GP, Miller ML, Liu LH, Erwin CR, Warner BW, Shull GE. Haploinsufficiency of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump, predisposes mice to squamous cell tumors via a novel mode of cancer susceptibility. Cancer Research. 65: 8655-61. PMID 16204033 DOI: 10.1158/0008-5472.Can-05-0026  0.388
2005 Hunt DL, King B, Kahn DM, Yamoah EN, Shull GE, Krubitzer L. Aberrant retinal projections in congenitally deaf mice: how are phenotypic characteristics specified in development and evolution? The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 287: 1051-66. PMID 16200647 DOI: 10.1002/Ar.A.20251  0.408
2005 Judd LM, Andringa A, Rubio CA, Spicer Z, Shull GE, Miller ML. Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors. Journal of Gastroenterology and Hepatology. 20: 1266-78. PMID 16048577 DOI: 10.1111/J.1440-1746.2005.03867.X  0.773
2005 Kintner DB, Look A, Shull GE, Sun D. Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2. American Journal of Physiology. Cell Physiology. 289: C934-45. PMID 15901600 DOI: 10.1152/Ajpcell.00092.2005  0.361
2005 Nicolet-Barousse L, Blanchard A, Roux C, Pietri L, Bloch-Faure M, Kolta S, Chappard C, Geoffroy V, Morieux C, Jeunemaitre X, Shull GE, Meneton P, Paillard M, Houillier P, De Vernejoul MC. Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 799-808. PMID 15824853 DOI: 10.1359/Jbmr.041238  0.402
2005 Xu J, Henriksnäs J, Barone S, Witte D, Shull GE, Forte JG, Holm L, Soleimani M. SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+. American Journal of Physiology. Cell Physiology. 289: C493-505. PMID 15800055 DOI: 10.1152/Ajpcell.00030.2005  0.416
2005 Gawenis LR, Greeb JM, Prasad V, Grisham C, Sanford LP, Doetschman T, Andringa A, Miller ML, Shull GE. Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. The Journal of Biological Chemistry. 280: 12781-9. PMID 15684419 DOI: 10.1074/Jbc.M414118200  0.547
2005 Chen H, Luo J, Kintner DB, Shull GE, Sun D. Na(+)-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 54-66. PMID 15678112 DOI: 10.1038/Sj.Jcbfm.9600006  0.45
2005 Ramos-Castañeda J, Park YN, Liu M, Hauser K, Rudolph H, Shull GE, Jonkman MF, Mori K, Ikeda S, Ogawa H, Arvan P. Deficiency of ATP2C1, a Golgi ion pump, induces secretory pathway defects in endoplasmic reticulum (ER)-associated degradation and sensitivity to ER stress. The Journal of Biological Chemistry. 280: 9467-73. PMID 15623514 DOI: 10.1074/Jbc.M413243200  0.328
2005 Xu Y, Zhang Z, Timofeyev V, Sharma D, Xu D, Tuteja D, Dong PH, Ahmmed GU, Ji Y, Shull GE, Periasamy M, Chiamvimonvat N. The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice. The Journal of Physiology. 562: 745-58. PMID 15564282 DOI: 10.1113/Jphysiol.2004.076216  0.387
2005 Noonan WT, Woo AL, Nieman ML, Prasad V, Schultheis PJ, Shull GE, Lorenz JN. Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R685-91. PMID 15550620 DOI: 10.1152/Ajpregu.00209.2004  0.414
2004 Bailey MA, Giebisch G, Abbiati T, Aronson PS, Gawenis LR, Shull GE, Wang T. NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice. The Journal of Physiology. 561: 765-75. PMID 15604231 DOI: 10.1113/Jphysiol.2004.074716  0.479
2004 Lenart B, Kintner DB, Shull GE, Sun D. Na-K-Cl cotransporter-mediated intracellular Na+ accumulation affects Ca2+ signaling in astrocytes in an in vitro ischemic model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9585-97. PMID 15509746 DOI: 10.1523/Jneurosci.2569-04.2004  0.403
2004 Schultheis PJ, Hagen TT, O'Toole KK, Tachibana A, Burke CR, McGill DL, Okunade GW, Shull GE. Characterization of the P5 subfamily of P-type transport ATPases in mice. Biochemical and Biophysical Research Communications. 323: 731-8. PMID 15381061 DOI: 10.1016/J.Bbrc.2004.08.156  0.373
2004 Loffing J, Vallon V, Loffing-Cueni D, Aregger F, Richter K, Pietri L, Bloch-Faure M, Hoenderop JG, Shull GE, Meneton P, Kaissling B. Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome. Journal of the American Society of Nephrology : Jasn. 15: 2276-88. PMID 15339977 DOI: 10.1097/01.Asn.0000138234.18569.63  0.451
2004 Prasad V, Okunade GW, Miller ML, Shull GE. Phenotypes of SERCA and PMCA knockout mice. Biochemical and Biophysical Research Communications. 322: 1192-203. PMID 15336967 DOI: 10.1016/J.Bbrc.2004.07.156  0.466
2004 Reinhardt TA, Lippolis JD, Shull GE, Horst RL. Null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2 impairs calcium transport into milk. The Journal of Biological Chemistry. 279: 42369-73. PMID 15302868 DOI: 10.1074/Jbc.M407788200  0.451
2004 Good DW, Watts BA, George T, Meyer JW, Shull GE. Transepithelial HCO3- absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice. American Journal of Physiology. Renal Physiology. 287: F1244-9. PMID 15292047 DOI: 10.1152/Ajprenal.00176.2004  0.445
2004 Gawenis LR, Hut H, Bot AG, Shull GE, de Jonge HR, Stien X, Miller ML, Clarke LL. Electroneutral sodium absorption and electrogenic anion secretion across murine small intestine are regulated in parallel. American Journal of Physiology. Gastrointestinal and Liver Physiology. 287: G1140-9. PMID 15284023 DOI: 10.1152/Ajpgi.00177.2004  0.475
2004 Okunade GW, Miller ML, Pyne GJ, Sutliff RL, O'Connor KT, Neumann JC, Andringa A, Miller DA, Prasad V, Doetschman T, Paul RJ, Shull GE. Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4. The Journal of Biological Chemistry. 279: 33742-50. PMID 15178683 DOI: 10.1074/Jbc.M404628200  0.422
2004 Gawenis LR, Ledoussal C, Judd LM, Prasad V, Alper SL, Stuart-Tilley A, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric. The Journal of Biological Chemistry. 279: 30531-9. PMID 15123620 DOI: 10.1074/Jbc.M403779200  0.813
2004 Gekle M, Völker K, Mildenberger S, Freudinger R, Shull GE, Wiemann M. NHE3 Na+/H+ exchanger supports proximal tubular protein reabsorption in vivo. American Journal of Physiology. Renal Physiology. 287: F469-73. PMID 15113744 DOI: 10.1152/Ajprenal.00059.2004  0.365
2004 Kintner DB, Su G, Lenart B, Ballard AJ, Meyer JW, Ng LL, Shull GE, Sun D. Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice. American Journal of Physiology. Cell Physiology. 287: C12-21. PMID 15013953 DOI: 10.1152/Ajpcell.00560.2003  0.387
2004 Bachmann O, Riederer B, Rossmann H, Groos S, Schultheis PJ, Shull GE, Gregor M, Manns MP, Seidler U. The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 287: G125-33. PMID 14962844 DOI: 10.1152/Ajpgi.00332.2003  0.442
2004 Clarke LL, Gawenis LR, Bradford EM, Judd LM, Boyle KT, Simpson JE, Shull GE, Tanabe H, Ouellette AJ, Franklin CL, Walker NM. Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G1050-8. PMID 14715526 DOI: 10.1152/Ajpgi.00393.2003  0.736
2004 Schultz Jel J, Glascock BJ, Witt SA, Nieman ML, Nattamai KJ, Liu LH, Lorenz JN, Shull GE, Kimball TR, Periasamy M. Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1146-53. PMID 14630633 DOI: 10.1152/Ajpheart.00720.2003  0.308
2003 Amlal H, Ledoussal C, Sheriff S, Shull GE, Soleimani M. Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+-H+ exchanger NHE3. The Journal of Physiology. 553: 511-22. PMID 14500765 DOI: 10.1113/Jphysiol.2003.053363  0.814
2003 Wang Y, Meyer JW, Ashraf M, Shull GE. Mice with a null mutation in the NHE1 Na+-H+ exchanger are resistant to cardiac ischemia-reperfusion injury. Circulation Research. 93: 776-82. PMID 12970112 DOI: 10.1161/01.Res.0000094746.24774.Dc  0.379
2003 Xu J, Barone S, Petrovic S, Wang Z, Seidler U, Riederer B, Ramaswamy K, Dudeja PK, Shull GE, Soleimani M. Identification of an apical Cl-/HCO3- exchanger in gastric surface mucous and duodenal villus cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G1225-34. PMID 12893630 DOI: 10.1152/Ajpgi.00236.2003  0.428
2003 Shull GE, Okunade G, Liu LH, Kozel P, Periasamy M, Lorenz JN, Prasad V. Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants. Annals of the New York Academy of Sciences. 986: 453-60. PMID 12763865 DOI: 10.1111/J.1749-6632.2003.Tb07229.X  0.797
2003 Woo AL, Noonan WT, Schultheis PJ, Neumann JC, Manning PA, Lorenz JN, Shull GE. Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect. American Journal of Physiology. Renal Physiology. 284: F1190-8. PMID 12582007 DOI: 10.1152/Ajprenal.00418.2002  0.521
2003 Paul RJ, Nobe K, Kranias E, Shull G, Lingrel J. PMCA, SERCA and Na, K ATPase Alpha Isoforms and Ca2+ Homeostasis in Smooth Muscle Evidence from Gene-Altered Mice Journal of Smooth Muscle Research Japanese Section. 7: J1-J35. DOI: 10.1540/Heikatsukinzashi1997.7.J1  0.434
2003 Elitsur N, Lorenz J, Sanford P, Hawkins J, Nieman M, Woo A, Shull G, Cohen MB. Uroguanylin but not guanylin knockout mice have diminished sodium excretion in response to an enteral salt load Gastroenterology. 124: A140. DOI: 10.1016/S0016-5085(03)80695-9  0.403
2003 Bachmann O, Rapedius M, Rossmann H, Wuechner K, Schultheis PJ, Shull GE, Seidler U. Nhe2 is predominantly crypt-localized in murine proximal colon and its lack causes an anion secretory defect in NHE2-/- mice Gastroenterology. 124: A40. DOI: 10.1016/S0016-5085(03)80197-X  0.451
2003 Gawenis LR, Miller ML, Ledoussal C, Judd LM, Shull GE. Gastric achlorhydria and abnormal incisor eruption in AE2 Cl-/HCO3- exchanger knockout mice Gastroenterology. 124: A3. DOI: 10.1016/S0016-5085(03)80016-1  0.804
2002 Arredouani A, Guiot Y, Jonas JC, Liu LH, Nenquin M, Pertusa JA, Rahier J, Rolland JF, Shull GE, Stevens M, Wuytack F, Henquin JC, Gilon P. SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells. Diabetes. 51: 3245-53. PMID 12401716 DOI: 10.2337/Diabetes.51.11.3245  0.338
2002 Meyer JW, Flagella M, Sutliff RL, Lorenz JN, Nieman ML, Weber CS, Paul RJ, Shull GE. Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1846-55. PMID 12384462 DOI: 10.1152/Ajpheart.00083.2002  0.764
2002 Petrovic S, Wang Z, Ma L, Seidler U, Forte JG, Shull GE, Soleimani M. Colocalization of the apical Cl-/HCO3- exchanger PAT1 and gastric H-K-ATPase in stomach parietal cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G1207-16. PMID 12381535 DOI: 10.1152/Ajpgi.00137.2002  0.479
2002 Woo AL, Gildea LA, Tack LM, Miller ML, Spicer Z, Millhorn DE, Finkelman FD, Hassett DJ, Shull GE. In vivo evidence for interferon-gamma-mediated homeostatic mechanisms in small intestine of the NHE3 Na+/H+ exchanger knockout model of congenital diarrhea. The Journal of Biological Chemistry. 277: 49036-46. PMID 12370192 DOI: 10.1074/Jbc.M205288200  0.78
2002 Miller ML, Judd LM, Van Driel IR, Andringa A, Flagella M, Bell SM, Schultheis PJ, Spicer Z, Shull GE. The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase. Cell and Tissue Research. 309: 369-80. PMID 12195293 DOI: 10.1007/S00441-002-0606-Z  0.82
2002 Paul RJ, Shull GE, Kranias EG. The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice. Novartis Foundation Symposium. 246: 228-38; discussion 2. PMID 12164311 DOI: 10.1002/0470853050.Ch17  0.382
2002 Walker NM, Flagella M, Gawenis LR, Shull GE, Clarke LL. An alternate pathway of cAMP-stimulated Cl secretion across the NKCC1-null murine duodenum. Gastroenterology. 123: 531-41. PMID 12145806 DOI: 10.1053/Gast.2002.34757  0.751
2002 Lu M, Wang T, Yan Q, Yang X, Dong K, Knepper MA, Wang W, Giebisch G, Shull GE, Hebert SC. Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. The Journal of Biological Chemistry. 277: 37881-7. PMID 12130653 DOI: 10.1074/Jbc.M206644200  0.487
2002 Lorenz JN, Baird NR, Judd LM, Noonan WT, Andringa A, Doetschman T, Manning PA, Liu LH, Miller ML, Shull GE. Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome. The Journal of Biological Chemistry. 277: 37871-80. PMID 12122007 DOI: 10.1074/Jbc.M205627200  0.452
2002 Shillingford JM, Miyoshi K, Flagella M, Shull GE, Hennighausen L. Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis. Molecular Endocrinology (Baltimore, Md.). 16: 1309-21. PMID 12040017 DOI: 10.1210/Mend.16.6.0857  0.787
2002 Nehrke K, Arreola J, Nguyen HV, Pilato J, Richardson L, Okunade G, Baggs R, Shull GE, Melvin JE. Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice. The Journal of Biological Chemistry. 277: 23604-11. PMID 11976342 DOI: 10.1074/Jbc.M202900200  0.424
2002 Gawenis LR, Stien X, Shull GE, Schultheis PJ, Woo AL, Walker NM, Clarke LL. Intestinal NaCl transport in NHE2 and NHE3 knockout mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 282: G776-84. PMID 11960774 DOI: 10.1152/Ajpgi.00297.2001  0.474
2002 Kozel PJ, Davis RR, Krieg EF, Shull GE, Erway LC. Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice. Hearing Research. 164: 231-9. PMID 11950541 DOI: 10.1016/S0378-5955(01)00420-8  0.803
2002 Su G, Kintner DB, Flagella M, Shull GE, Sun D. Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release. American Journal of Physiology. Cell Physiology. 282: C1147-60. PMID 11940530 DOI: 10.1152/Ajpcell.00538.2001  0.743
2002 Petrovic S, Spicer Z, Greeley T, Shull GE, Soleimani M. Novel Schering and ouabain-insensitive potassium-dependent proton secretion in the mouse cortical collecting duct. American Journal of Physiology. Renal Physiology. 282: F133-43. PMID 11739121 DOI: 10.1152/Ajprenal.0124.2001  0.801
2001 Ledoussal C, Woo AL, Miller ML, Shull GE. Loss of the NHE2 Na(+)/H(+) exchanger has no apparent effect on diarrheal state of NHE3-deficient mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1385-96. PMID 11705743 DOI: 10.1152/Ajpgi.2001.281.6.G1385  0.825
2001 Spicer Z, Clarke LL, Gawenis LR, Shull GE. Colonic H(+)-K(+)-ATPase in K(+) conservation and electrogenic Na(+) absorption during Na(+) restriction. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1369-77. PMID 11705741 DOI: 10.1152/Ajpgi.2001.281.6.G1369  0.789
2001 Ledoussal C, Lorenz JN, Nieman ML, Soleimani M, Schultheis PJ, Shull GE. Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2. American Journal of Physiology. Renal Physiology. 281: F718-27. PMID 11553519 DOI: 10.1152/Ajprenal.2001.281.4.F718  0.816
2001 Rossmann H, Bachmann O, Wang Z, Shull GE, Obermaier B, Stuart-Tilley A, Alper SL, Seidler U. Differential expression and regulation of AE2 anion exchanger subtypes in rabbit parietal and mucous cells. The Journal of Physiology. 534: 837-48. PMID 11483713 DOI: 10.1111/J.1469-7793.2001.00837.X  0.367
2001 Wang T, Yang CL, Abbiati T, Shull GE, Giebisch G, Aronson PS. Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule. American Journal of Physiology. Renal Physiology. 281: F288-92. PMID 11457720 DOI: 10.1152/Ajprenal.2001.281.2.F288  0.473
2001 Liu LH, Boivin GP, Prasad V, Periasamy M, Shull GE. Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump. The Journal of Biological Chemistry. 276: 26737-40. PMID 11389134 DOI: 10.1074/Jbc.C100275200  0.451
2001 Zhao XS, Shin DM, Liu LH, Shull GE, Muallem S. Plasticity and adaptation of Ca2+ signaling and Ca2+-dependent exocytosis in SERCA2(+/-) mice. The Embo Journal. 20: 2680-9. PMID 11387203 DOI: 10.1093/Emboj/20.11.2680  0.378
2001 Park K, Evans RL, Watson GE, Nehrke K, Richardson L, Bell SM, Schultheis PJ, Hand AR, Shull GE, Melvin JE. Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice. The Journal of Biological Chemistry. 276: 27042-50. PMID 11358967 DOI: 10.1074/Jbc.M102901200  0.591
2001 Mennone A, Biemesderfer D, Negoianu D, Yang CL, Abbiati T, Schultheis PJ, Shull GE, Aronson PS, Boyer JL. Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes American Journal of Physiology - Gastrointestinal and Liver Physiology. 280: G247-G254. PMID 11208547 DOI: 10.1152/Ajpgi.2001.280.2.G247  0.435
2001 Brooks HL, Sorensen AM, Terris J, Schultheis PJ, Lorenz JN, Shull GE, Knepper MA. Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics. The Journal of Physiology. 530: 359-66. PMID 11158268 DOI: 10.1111/J.1469-7793.2001.0359K.X  0.523
2000 Melvin JE, Nguyen HV, Evans RL, Shull GE. What can transgenic and gene-targeted mouse models teach us about salivary gland physiology? Advances in Dental Research. 14: 5-11. PMID 11842924 DOI: 10.1177/08959374000140010801  0.407
2000 Ji Y, Lalli MJ, Babu GJ, Xu Y, Kirkpatrick DL, Liu LH, Chiamvimonvat N, Walsh RA, Shull GE, Periasamy M. Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function. The Journal of Biological Chemistry. 275: 38073-80. PMID 10970890 DOI: 10.1074/Jbc.M004804200  0.365
2000 Shull GE. Gene knockout studies of Ca2+-transporting ATPases. European Journal of Biochemistry. 267: 5284-90. PMID 10951186 DOI: 10.1046/J.1432-1327.2000.01568.X  0.348
2000 Wheat VJ, Shumaker H, Burnham C, Shull GE, Yankaskas JR, Soleimani M. CFTR induces the expression of DRA along with Cl(-)/HCO(3)(-) exchange activity in tracheal epithelial cells. American Journal of Physiology. Cell Physiology. 279: C62-71. PMID 10898717 DOI: 10.1152/Ajpcell.2000.279.1.C62  0.417
2000 Lee MG, Ahn W, Choi JY, Luo X, Seo JT, Schultheis PJ, Shull GE, Kim KH, Muallem S. Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct. The Journal of Clinical Investigation. 105: 1651-8. PMID 10841524 DOI: 10.1172/Jci9207  0.459
2000 Evans RL, Park K, Turner RJ, Watson GE, Nguyen HV, Dennett MR, Hand AR, Flagella M, Shull GE, Melvin JE. Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice. The Journal of Biological Chemistry. 275: 26720-6. PMID 10831596 DOI: 10.1074/Jbc.M003753200  0.816
2000 Choi JY, Shah M, Lee MG, Schultheis PJ, Shull GE, Muallem S, Baum M. Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule. The Journal of Clinical Investigation. 105: 1141-6. PMID 10772659 DOI: 10.1172/Jci9260  0.51
2000 Spicer Z, Miller ML, Andringa A, Riddle TM, Duffy JJ, Doetschman T, Shull GE. Stomachs of mice lacking the gastric H,K-ATPase alpha -subunit have achlorhydria, abnormal parietal cells, and ciliated metaplasia. The Journal of Biological Chemistry. 275: 21555-65. PMID 10764766 DOI: 10.1074/Jbc.M001558200  0.784
2000 Szabó EZ, Numata M, Shull GE, Orlowski J. Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells. The Journal of Biological Chemistry. 275: 6302-7. PMID 10692428 DOI: 10.1074/Jbc.275.9.6302  0.433
2000 Nguyen HV, Shull GE, Melvin JE. Muscarinic receptor-induced acidification in sublingual mucous acinar cells: Loss of pH recovery in Na+-H+ exchanger-1 deficient mice Journal of Physiology. 523: 139-146. PMID 10673550 DOI: 10.1111/J.1469-7793.2000.T01-2-00139.X  0.403
2000 Shull GE, Miller ML, Schultheis PJ. Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract. American Journal of Physiology. Gastrointestinal and Liver Physiology. 278: G185-90. PMID 10666041 DOI: 10.1152/Ajpgi.2000.278.2.G185  0.424
2000 Loukianov E, Ji Y, Baker DL, Reed T, Babu J, Loukianova T, Greene A, Shull G, Periasamy M. Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology. Annals of the New York Academy of Sciences. 853: 251-9. PMID 10603953 DOI: 10.1111/J.1749-6632.1998.Tb08273.X  0.421
2000 Gawenis LR, Schultheis P, Shull G, Clarke LL. Contribution of NHE2 and NHE3 to Na absorption in the murine jejunum Gastroenterology. 118: A871. DOI: 10.1016/S0016-5085(00)85623-1  0.393
2000 Walker NM, Flagella M, Gawenis LR, Shull G, Clarke LL. CAMP stimulated anion secretion across NKCC1 knockout intestine Gastroenterology. 118: A605. DOI: 10.1016/S0016-5085(00)84559-X  0.73
1999 Nakamura S, Amlal H, Schultheis PJ, Galla JH, Shull GE, Soleimani M. [Formula: see text] reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response. American Journal of Physiology. Renal Physiology. 276: F914-F921. PMID 29591382 DOI: 10.1152/Ajprenal.1999.276.6.F914  0.484
1999 Evans RL, Bell SM, Schultheis PJ, Shull GE, Melvin JE. Targeted disruption of the Nhe1 gene prevents muscarinic agonist-induced up-regulation of Na(+)/H(+) exchange in mouse parotid acinar cells. The Journal of Biological Chemistry. 274: 29025-30. PMID 10506152 DOI: 10.1074/Jbc.274.41.29025  0.477
1999 Lorenz JN, Schultheis PJ, Traynor T, Shull GE, Schnermann J. Micropuncture analysis of single-nephron function in NHE3-deficient mice. The American Journal of Physiology. 277: F447-53. PMID 10484528 DOI: 10.1152/Ajprenal.1999.277.3.F447  0.503
1999 Flagella M, Clarke LL, Miller ML, Erway LC, Giannella RA, Andringa A, Gawenis LR, Kramer J, Duffy JJ, Doetschman T, Lorenz JN, Yamoah EN, Cardell EL, Shull GE. Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf. The Journal of Biological Chemistry. 274: 26946-55. PMID 10480906 DOI: 10.1074/Jbc.274.38.26946  0.804
1999 Wang T, Yang CL, Abbiati T, Schultheis PJ, Shull GE, Giebisch G, Aronson PS. Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. The American Journal of Physiology. 277: F298-302. PMID 10444585 DOI: 10.1152/Ajprenal.1999.277.2.F298  0.504
1999 Kao J, Fortner CN, Liu LH, Shull GE, Paul RJ. Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle. The American Journal of Physiology. 277: L264-70. PMID 10444520 DOI: 10.1152/Ajplung.1999.277.2.L264  0.357
1999 Melvin JE, Park K, Richardson L, Schultheis PJ, Shull GE. Mouse down-regulated in adenoma (DRA) is an intestinal Cl(-)/HCO(3)(-) exchanger and is up-regulated in colon of mice lacking the NHE3 Na(+)/H(+) exchanger. The Journal of Biological Chemistry. 274: 22855-61. PMID 10428871 DOI: 10.1074/Jbc.274.32.22855  0.552
1999 Bell SM, Schreiner CM, Schultheis PJ, Miller ML, Evans RL, Vorhees CV, Shull GE, Scott WJ. Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. The American Journal of Physiology. 276: C788-95. PMID 10199808 DOI: 10.1152/Ajpcell.1999.276.4.C788  0.363
1999 Baird NR, Orlowski J, Szabó EZ, Zaun HC, Schultheis PJ, Menon AG, Shull GE. Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain. The Journal of Biological Chemistry. 274: 4377-82. PMID 9933641 DOI: 10.1074/Jbc.274.7.4377  0.36
1999 Periasamy M, Reed TD, Liu LH, Ji Y, Loukianov E, Paul RJ, Nieman ML, Riddle T, Duffy JJ, Doetschman T, Lorenz JN, Shull GE. Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene. The Journal of Biological Chemistry. 274: 2556-62. PMID 9891028 DOI: 10.1074/Jbc.274.4.2556  0.398
1998 Burnham CE, Flagella M, Wang Z, Amlal H, Shull GE, Soleimani M. Cloning, renal distribution, and regulation of the rat Na-[Formula: see text]cotransporter. American Journal of Physiology. Renal Physiology. 274: F1119-F1126. PMID 29586038 DOI: 10.1152/ajprenal.1998.274.6.F1119  0.709
1998 Burnham CE, Flagella M, Wang Z, Amlal H, Shull GE, Soleimani M. Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter. The American Journal of Physiology. 274: F1119-26. PMID 9841505 DOI: 10.1152/Ajprenal.1998.274.6.F1119  0.727
1998 Lee MG, Schultheis PJ, Yan M, Shull GE, Bookstein C, Chang E, Tse M, Donowitz M, Park K, Muallem S. Membrane-limited expression and regulation of Na+-H+ exchanger isoforms by P2 receptors in the rat submandibular gland duct. The Journal of Physiology. 513: 341-57. PMID 9806987 DOI: 10.1111/J.1469-7793.1998.341Bb.X  0.402
1998 Schultheis PJ, Lorenz JN, Meneton P, Nieman ML, Riddle TM, Flagella M, Duffy JJ, Doetschman T, Miller ML, Shull GE. Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule. The Journal of Biological Chemistry. 273: 29150-5. PMID 9786924 DOI: 10.1074/Jbc.273.44.29150  0.801
1998 Kozel PJ, Friedman RA, Erway LC, Yamoah EN, Liu LH, Riddle T, Duffy JJ, Doetschman T, Miller ML, Cardell EL, Shull GE. Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2. The Journal of Biological Chemistry. 273: 18693-6. PMID 9668038 DOI: 10.1074/Jbc.273.30.18693  0.828
1998 Schultheis PJ, Clarke LL, Meneton P, Miller ML, Soleimani M, Gawenis LR, Riddle TM, Duffy JJ, Doetschman T, Wang T, Giebisch G, Aronson PS, Lorenz JN, Shull GE. Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nature Genetics. 19: 282-5. PMID 9662405 DOI: 10.1038/969  0.567
1998 Schultheis PJ, Clarke LL, Meneton P, Harline M, Boivin GP, Stemmermann G, Duffy JJ, Doetschman T, Miller ML, Shull GE. Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. The Journal of Clinical Investigation. 101: 1243-53. PMID 9502765 DOI: 10.1172/Jci1249  0.473
1998 Meneton P, Schultheis PJ, Greeb J, Nieman ML, Liu LH, Clarke LL, Duffy JJ, Doetschman T, Lorenz JN, Shull GE. Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice. The Journal of Clinical Investigation. 101: 536-42. PMID 9449685 DOI: 10.1172/Jci1720  0.455
1997 Liu LH, Paul RJ, Sutliff RL, Miller ML, Lorenz JN, Pun RY, Duffy JJ, Doetschman T, Kimura Y, MacLennan DH, Hoying JB, Shull GE. Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. The Journal of Biological Chemistry. 272: 30538-45. PMID 9374548 DOI: 10.1074/Jbc.272.48.30538  0.37
1997 Burnham CE, Amlal H, Wang Z, Shull GE, Soleimani M. Cloning and functional expression of a human kidney Na+:HCO3- cotransporter. The Journal of Biological Chemistry. 272: 19111-4. PMID 9235899 DOI: 10.1074/Jbc.272.31.19111  0.391
1997 Wang Z, Rabb H, Craig T, Burnham C, Shull GE, Soleimani M. Ischemic-reperfusion injury in the kidney: overexpression of colonic H+-K+-ATPase and suppression of NHE-3. Kidney International. 51: 1106-15. PMID 9083276 DOI: 10.1038/Ki.1997.153  0.405
1997 Pathak BG, Shull GE, Jenkins NA, Copeland NG. Mouse chromosomal location of four Na/H exchanger isoform genes. Genomics. 31: 261-3. PMID 8824815 DOI: 10.1006/Geno.1996.0045  0.317
1996 Cougnon M, Planelles G, Crowson MS, Shull GE, Rossier BC, Jaisser F. The rat distal colon P-ATPase alpha subunit encodes a ouabain-sensitive H+, K+-ATPase. The Journal of Biological Chemistry. 271: 7277-80. PMID 8631741 DOI: 10.1074/Jbc.271.13.7277  0.339
1993 Shull GE, Clarke DM, Gunteski-Hamblin AM. cDNA cloning of possible mammalian homologs of the yeast secretory pathway Ca(2+)-transporting ATPase. Annals of the New York Academy of Sciences. 671: 70-80; discussion 81. PMID 1288355 DOI: 10.1111/J.1749-6632.1992.Tb43785.X  0.343
1992 Newman PR, Shull GE. Rat gastric H,K-ATPase beta-subunit gene: intron/exon organization, identification of multiple transcription initiation sites, and analysis of the 5'-flanking region. Genomics. 11: 252-62. PMID 1663070 DOI: 10.1016/0888-7543(91)90131-W  0.306
1992 Gunteski-Hamblin AM, Clarke DM, Shull GE. Molecular cloning and tissue distribution of alternatively spliced mRNAs encoding possible mammalian homologues of the yeast secretory pathway calcium pump. Biochemistry. 31: 7600-8. PMID 1380825 DOI: 10.1021/Bi00148A023  0.337
1990 Newman PR, Greeb J, Keeton TP, Reyes AA, Shull GE. Structure of the human gastric H,K-ATPase gene and comparison of the 5'-flanking sequences of the human and rat genes Dna and Cell Biology. 9: 749-762. PMID 2176086 DOI: 10.1089/Dna.1990.9.749  0.327
1986 Shull GE, Lane LK, Lingrel JB. Amino-acid sequence of the beta-subunit of the (Na+ + K+)ATPase deduced from a cDNA. Nature. 321: 429-31. PMID 3012356 DOI: 10.1038/321429A0  0.363
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