Year |
Citation |
Score |
2020 |
Medina-Pérez DN, Wager B, Troy E, Gao L, Norris SJ, Lin T, Hu L, Hyde JA, Lybecker M, Skare JT. The intergenic small non-coding RNA ittA is required for optimal infectivity and tissue tropism in Borrelia burgdorferi. Plos Pathogens. 16: e1008423. PMID 32365143 DOI: 10.1371/Journal.Ppat.1008423 |
0.305 |
|
2019 |
Fitzgerald BL, Molins CR, Islam MN, Graham B, Hove PR, Wormser GP, Hu L, Ashton LV, Belisle JT. Host Metabolic Response in Early Lyme Disease. Journal of Proteome Research. PMID 31821002 DOI: 10.1021/Acs.Jproteome.9B00470 |
0.301 |
|
2019 |
Cornacchione LP, Klein BA, Duncan MJ, Hu LT. Interspecies inhibition of by yogurt-derived require active pyruvate oxidase. Applied and Environmental Microbiology. PMID 31285191 DOI: 10.1128/Aem.01271-19 |
0.305 |
|
2019 |
Phelan JP, Kern A, Ramsey ME, Lundt ME, Sharma B, Lin T, Gao L, Norris SJ, Hyde JA, Skare JT, Hu LT. Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector. Plos Pathogens. 15: e1007644. PMID 31086414 DOI: 10.1371/Journal.Ppat.1007644 |
0.331 |
|
2018 |
Wu X, Sharma B, Niles S, O'Connor K, Schilling R, Matluck N, D'Onofrio A, Hu LT, Lewis K. Identifying vancomycin as an effective antibiotic for killing . Antimicrobial Agents and Chemotherapy. PMID 30126963 DOI: 10.1128/Aac.01201-18 |
0.353 |
|
2017 |
Killpack TL, Ballesteros M, Bunnell SC, Bedugnis A, Kobzik L, Hu LT, Petnicki-Ocwieja T. Phagocytic receptors activate Syk and Src signaling during Borrelia burgdorferi phagocytosis. Infection and Immunity. PMID 28717031 DOI: 10.1128/Iai.00004-17 |
0.318 |
|
2017 |
Ramsey ME, Hyde JA, Medina-Perez DN, Lin T, Gao L, Lundt ME, Li X, Norris SJ, Skare JT, Hu LT. A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species. Plos Pathogens. 13: e1006225. PMID 28212410 DOI: 10.1371/Journal.Ppat.1006225 |
0.339 |
|
2016 |
Kern A, Zhou CW, Jia F, Xu Q, Hu LT. Live-vaccinia virus encapsulation in pH-sensitive polymer increases safety of a reservoir-targeted Lyme disease vaccine by targeting gastrointestinal release. Vaccine. PMID 27502570 DOI: 10.1016/J.Vaccine.2016.07.059 |
0.355 |
|
2016 |
Wang Y, Kern A, Boatright NK, Schiller ZA, Sadowski A, Ejemel M, Souders CA, Reimann KA, Hu L, Thomas WD, Klempner MS. Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes. The Journal of Infectious Diseases. 214: 205-11. PMID 27338767 DOI: 10.1093/Infdis/Jiw151 |
0.358 |
|
2016 |
Troy EB, Lin T, Gao L, Lazinski DW, Lundt M, Camilli A, Norris SJ, Hu LT. Global Tn-seq Analysis of Carbohydrate Utilization and Vertebrate Infectivity of Borrelia burgdorferi. Molecular Microbiology. PMID 27279039 DOI: 10.1111/Mmi.13437 |
0.369 |
|
2016 |
Sanchez E, Vannier E, Wormser GP, Hu LT. Diagnosis, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: A Review. Jama. 315: 1767-77. PMID 27115378 DOI: 10.1001/Jama.2016.2884 |
0.336 |
|
2015 |
Petnicki-Ocwieja T, Kern A, Killpack TL, Bunnell SC, Hu LT. Adaptor Protein-3-Mediated Trafficking of TLR2 Ligands Controls Specificity of Inflammatory Responses but Not Adaptor Complex Assembly. Journal of Immunology (Baltimore, Md. : 1950). 195: 4331-40. PMID 26423153 DOI: 10.4049/Jimmunol.1501268 |
0.33 |
|
2015 |
Sharma B, Brown AV, Matluck NE, Hu LT, Lewis K. Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells. Antimicrobial Agents and Chemotherapy. 59: 4616-24. PMID 26014929 DOI: 10.1128/Aac.00864-15 |
0.343 |
|
2014 |
Telford SR, Hu LT, Marques A. Is there a place for xenodiagnosis in the clinic? Expert Review of Anti-Infective Therapy. 12: 1307-10. PMID 25301228 DOI: 10.1586/14787210.2014.966084 |
0.353 |
|
2014 |
Lin T, Troy EB, Hu LT, Gao L, Norris SJ. Transposon mutagenesis as an approach to improved understanding of Borrelia pathogenesis and biology. Frontiers in Cellular and Infection Microbiology. 4: 63. PMID 24904839 DOI: 10.3389/Fcimb.2014.00063 |
0.325 |
|
2014 |
Marques A, Telford SR, Turk SP, Chung E, Williams C, Dardick K, Krause PJ, Brandeburg C, Crowder CD, Carolan HE, Eshoo MW, Shaw PA, Hu LT. Xenodiagnosis to detect Borrelia burgdorferi infection: a first-in-human study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 937-45. PMID 24523212 DOI: 10.1093/Cid/Cit939 |
0.343 |
|
2013 |
Troy EB, Lin T, Gao L, Lazinski DW, Camilli A, Norris SJ, Hu LT. Understanding barriers to Borrelia burgdorferi dissemination during infection using massively parallel sequencing. Infection and Immunity. 81: 2347-57. PMID 23608706 DOI: 10.1128/Iai.00266-13 |
0.376 |
|
2012 |
Klein BA, Tenorio EL, Lazinski DW, Camilli A, Duncan MJ, Hu LT. Identification of essential genes of the periodontal pathogen Porphyromonas gingivalis. Bmc Genomics. 13: 578. PMID 23114059 DOI: 10.1186/1471-2164-13-578 |
0.313 |
|
2012 |
Bensaci M, Bhattacharya D, Clark R, Hu LT. Oral vaccination with vaccinia virus expressing the tick antigen subolesin inhibits tick feeding and transmission of Borrelia burgdorferi. Vaccine. 30: 6040-6. PMID 22864146 DOI: 10.1016/J.Vaccine.2012.07.053 |
0.576 |
|
2012 |
Radolf JD, Caimano MJ, Stevenson B, Hu LT. Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes. Nature Reviews. Microbiology. 10: 87-99. PMID 22230951 DOI: 10.1038/Nrmicro2714 |
0.353 |
|
2011 |
Tenorio EL, Klein BA, Cheung WS, Hu LT. Identification of interspecies interactions affecting Porphyromonas gingivalis virulence phenotypes. Journal of Oral Microbiology. 3. PMID 22022641 DOI: 10.3402/Jom.V3I0.8396 |
0.313 |
|
2011 |
Telford SR, Cunningham JA, Waltari E, Hu L. Nest box-deployed bait for delivering oral vaccines to white-footed mice. Ticks and Tick-Borne Diseases. 2: 151-155. PMID 21890068 DOI: 10.1016/J.Ttbdis.2011.06.001 |
0.348 |
|
2011 |
Bhattacharya D, Bensaci M, Luker KE, Luker G, Wisdom S, Telford SR, Hu LT. Development of a baited oral vaccine for use in reservoir-targeted strategies against Lyme disease. Vaccine. 29: 7818-25. PMID 21816190 DOI: 10.1016/J.Vaccine.2011.07.100 |
0.589 |
|
2011 |
Petnicki-Ocwieja T, DeFrancesco AS, Chung E, Darcy CT, Bronson RT, Kobayashi KS, Hu LT. Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance. Plos One. 6: e17414. PMID 21387014 DOI: 10.1371/Journal.Pone.0017414 |
0.383 |
|
2010 |
Marre ML, Darcy CT, Yinh J, Akira S, Uematsu S, Steere AC, Hu LT. Role of adrenomedullin in Lyme disease. Infection and Immunity. 78: 5307-13. PMID 20921145 DOI: 10.1128/Iai.00630-10 |
0.349 |
|
2010 |
Bhattacharya D, Mecsas J, Hu LT. Development of a vaccinia virus based reservoir-targeted vaccine against Yersinia pestis. Vaccine. 28: 7683-9. PMID 20875494 DOI: 10.1016/J.Vaccine.2010.09.039 |
0.563 |
|
2009 |
Shin OS, Miller LS, Modlin RL, Akira S, Uematsu S, Hu LT. Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K. Journal of Immunology (Baltimore, Md. : 1950). 183: 491-8. PMID 19542460 DOI: 10.4049/Jimmunol.0900724 |
0.326 |
|
2009 |
Heilpern AJ, Wertheim W, He J, Perides G, Bronson RT, Hu LT. Matrix metalloproteinase 9 plays a key role in lyme arthritis but not in dissemination of Borrelia burgdorferi. Infection and Immunity. 77: 2643-9. PMID 19364840 DOI: 10.1128/Iai.00214-09 |
0.307 |
|
2008 |
Clark RP, Hu LT. Prevention of lyme disease and other tick-borne infections. Infectious Disease Clinics of North America. 22: 381-96, vii. PMID 18755380 DOI: 10.1016/J.Idc.2008.03.007 |
0.344 |
|
2008 |
Behera AK, Durand E, Cugini C, Antonara S, Bourassa L, Hildebrand E, Hu LT, Coburn J. Borrelia burgdorferi BBB07 interaction with integrin alpha3beta1 stimulates production of pro-inflammatory mediators in primary human chondrocytes. Cellular Microbiology. 10: 320-31. PMID 17822440 DOI: 10.1111/J.1462-5822.2007.01043.X |
0.311 |
|
2007 |
Klempner MS, Unnasch TR, Hu LT. Taking a bite out of vector-transmitted infectious diseases. The New England Journal of Medicine. 356: 2567-9. PMID 17582066 DOI: 10.1056/Nejmp078081 |
0.315 |
|
2007 |
Scheckelhoff MR, Telford SR, Wesley M, Hu LT. Borrelia burgdorferi intercepts host hormonal signals to regulate expression of outer surface protein A. Proceedings of the National Academy of Sciences of the United States of America. 104: 7247-52. PMID 17438273 DOI: 10.1073/Pnas.0607263104 |
0.371 |
|
2007 |
Shin OS, Behera AK, Bronson RT, Hu LT. Role of novel protein kinase C isoforms in Lyme arthritis. Cellular Microbiology. 9: 1987-96. PMID 17394560 DOI: 10.1111/J.1462-5822.2007.00929.X |
0.342 |
|
2007 |
Medrano MS, Ding Y, Wang XG, Lu P, Coburn J, Hu LT. Regulators of expression of the oligopeptide permease A proteins of Borrelia burgdorferi. Journal of Bacteriology. 189: 2653-9. PMID 17237172 DOI: 10.1128/Jb.01760-06 |
0.334 |
|
2006 |
Behera AK, Hildebrand E, Szafranski J, Hung HH, Grodzinsky AJ, Lafyatis R, Koch AE, Kalish R, Perides G, Steere AC, Hu LT. Role of aggrecanase 1 in Lyme arthritis. Arthritis and Rheumatism. 54: 3319-29. PMID 17009305 DOI: 10.1002/Art.22128 |
0.356 |
|
2006 |
Behera AK, Hildebrand E, Uematsu S, Akira S, Coburn J, Hu LT. Identification of a TLR-independent pathway for Borrelia burgdorferi-induced expression of matrix metalloproteinases and inflammatory mediators through binding to integrin alpha 3 beta 1. Journal of Immunology (Baltimore, Md. : 1950). 177: 657-64. PMID 16785564 DOI: 10.4049/Jimmunol.177.1.657 |
0.352 |
|
2006 |
Behera AK, Hildebrand E, Bronson RT, Perides G, Uematsu S, Akira S, Hu LT. MyD88 deficiency results in tissue-specific changes in cytokine induction and inflammation in interleukin-18-independent mice infected with Borrelia burgdorferi. Infection and Immunity. 74: 1462-70. PMID 16495516 DOI: 10.1128/Iai.74.3.1462-1470.2006 |
0.358 |
|
2006 |
Scheckelhoff MR, Telford SR, Hu LT. Protective efficacy of an oral vaccine to reduce carriage of Borrelia burgdorferi (strain N40) in mouse and tick reservoirs. Vaccine. 24: 1949-57. PMID 16300863 DOI: 10.1016/J.Vaccine.2005.10.044 |
0.423 |
|
2005 |
Behera AK, Hildebrand E, Scagliotti J, Steere AC, Hu LT. Induction of host matrix metalloproteinases by Borrelia burgdorferi differs in human and murine lyme arthritis. Infection and Immunity. 73: 126-34. PMID 15618147 DOI: 10.1128/Iai.73.1.126-134.2005 |
0.338 |
|
2004 |
Behera AK, Thorpe CM, Kidder JM, Smith W, Hildebrand E, Hu LT. Borrelia burgdorferi-induced expression of matrix metalloproteinases from human chondrocytes requires mitogen-activated protein kinase and Janus kinase/signal transducer and activator of transcription signaling pathways. Infection and Immunity. 72: 2864-71. PMID 15102798 DOI: 10.1128/Iai.72.5.2864-2871.2004 |
0.327 |
|
2004 |
Wang XG, Scagliotti JP, Hu LT. Phospholipid synthesis in Borrelia burgdorferi: BB0249 and BB0721 encode functional phosphatidylcholine synthase and phosphatidylglycerolphosphate synthase proteins. Microbiology (Reading, England). 150: 391-7. PMID 14766917 DOI: 10.1099/Mic.0.26752-0 |
0.31 |
|
2002 |
Wang XG, Lin B, Kidder JM, Telford S, Hu LT. Effects of environmental changes on expression of the oligopeptide permease (opp) genes of Borrelia burgdorferi. Journal of Bacteriology. 184: 6198-206. PMID 12399490 DOI: 10.1128/Jb.184.22.6198-6206.2002 |
0.316 |
|
2002 |
McDowell JV, Sung SY, Hu LT, Marconi RT. Evidence that the variable regions of the central domain of VlsE are antigenic during infection with lyme disease spirochetes. Infection and Immunity. 70: 4196-203. PMID 12117928 DOI: 10.1128/Iai.70.8.4196-4203.2002 |
0.346 |
|
1997 |
Hu LT, Klempner MS. Host—Pathogen Interactions in the Immunopathogenesis of Lyme Disease Journal of Clinical Immunology. 17: 354-365. PMID 9327334 DOI: 10.1023/A:1027308122565 |
0.356 |
|
1995 |
Hu LT, Perides G, Noring R, Klempner MS. Binding of human plasminogen to Borrelia burgdorferi. Infection and Immunity. 63: 3491-3496. PMID 7642282 DOI: 10.1128/Iai.63.9.3491-3496.1995 |
0.308 |
|
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