Year |
Citation |
Score |
2022 |
Simbulan-Rosenthal CM, Haribabu Y, Vakili S, Kuo LW, Clark H, Dougherty R, Alobaidi R, Carney B, Sykora P, Rosenthal DS. Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells. International Journal of Molecular Sciences. 23. PMID 35216449 DOI: 10.3390/ijms23042333 |
0.413 |
|
2017 |
Simbulan-Rosenthal CM, Dakshanamurthy S, Gaur A, Chen YS, Fang HB, Abdussamad M, Zhou H, Zapas J, Calvert V, Petricoin EF, Atkins MB, Byers SW, Rosenthal DS. The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma. Oncotarget. PMID 28157711 DOI: 10.18632/oncotarget.14990 |
0.311 |
|
2016 |
Dakic A, DiVito K, Fang S, Suprynowicz F, Gaur A, Li X, Palechor-Ceron N, Simic V, Choudhury S, Yu S, Simbulan-Rosenthal CM, Rosenthal D, Schlegel R, Liu X. ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes. Oncotarget. PMID 27556514 DOI: 10.18632/Oncotarget.11458 |
0.629 |
|
2015 |
Chen YS, Aubee J, DiVito KA, Zhou H, Zhang W, Chou FP, Simbulan-Rosenthal CM, Rosenthal DS. Id3 induces an Elk-1-caspase-8-dependent apoptotic pathway in squamous carcinoma cells. Cancer Medicine. 4: 914-24. PMID 25693514 DOI: 10.1002/cam4.427 |
0.597 |
|
2015 |
Dakic A, Divito K, Fang S, Palechor-Ceron N, Simic V, Choudhury S, Yu S, Simbulan-Rosenthal CM, Rosenthal D, Schlegel R, Liu X. Abstract 5145: Y-27632 inhibits Myc-induced apoptosis and cooperates with Myc to immortalize human keratinocytes Cancer Research. 75: 5145-5145. DOI: 10.1158/1538-7445.Am2015-5145 |
0.559 |
|
2013 |
Chen Y, Rosenthal C, Rosenthal D. Abstract 825: Id3: Tumor suppressor of squamous cell carcinoma. Cancer Research. 73: 825-825. DOI: 10.1158/1538-7445.Am2013-825 |
0.565 |
|
2010 |
Ringer L, Sirajuddin P, Yenugonda VM, Ghosh A, Divito K, Trabosh V, Patel Y, Brophy A, Grindrod S, Lisanti MP, Rosenthal D, Brown ML, Avantaggiati ML, Rodriguez O, Albanese C. VMY-1-103, a dansylated analog of purvalanol B, induces caspase-3-dependent apoptosis in LNCaP prostate cancer cells. Cancer Biology & Therapy. 10: 320-5. PMID 20574155 DOI: 10.4161/Cbt.10.4.12208 |
0.473 |
|
2010 |
Ray R, Simbulan-Rosenthal CM, Keyser BM, Benton B, Anderson D, Holmes W, Trabosh VA, Daher A, Rosenthal DS. Sulfur mustard induces apoptosis in lung epithelial cells via a caspase amplification loop. Toxicology. 271: 94-9. PMID 20226831 DOI: 10.1016/J.Tox.2010.03.008 |
0.695 |
|
2009 |
Trabosh VA, Divito KA, D Aguda B, Simbulan-Rosenthal CM, Rosenthal DS. Sequestration of E12/E47 and suppression of p27KIP1 play a role in Id2-induced proliferation and tumorigenesis. Carcinogenesis. 30: 1252-9. PMID 19451188 DOI: 10.1093/carcin/bgp115 |
0.389 |
|
2009 |
Trabosh VA, Daher A, Divito KA, Amin K, Simbulan-Rosenthal CM, Rosenthal DS. UVB upregulates the bax promoter in immortalized human keratinocytes via ROS induction of Id3. Experimental Dermatology. 18: 387-95. PMID 19054058 DOI: 10.1111/J.1600-0625.2008.00801.X |
0.628 |
|
2008 |
Ray R, Keyser B, Benton B, Daher A, Simbulan-Rosenthal CM, Rosenthal DS. Sulfur mustard induces apoptosis in cultured normal human airway epithelial cells: evidence of a dominant caspase-8-mediated pathway and differential cellular responses. Drug and Chemical Toxicology. 31: 137-48. PMID 18161513 DOI: 10.1080/01480540701688840 |
0.679 |
|
2007 |
Li W, Hardwick MJ, Rosenthal D, Culty M, Papadopoulos V. Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation. Biochemical Pharmacology. 73: 491-503. PMID 17126818 DOI: 10.1016/J.Bcp.2006.10.025 |
0.482 |
|
2007 |
Ray R, Benton B, Keyser B, Carpin C, Rosenthal D. Sulfur mustard‐induced apoptosis in human airway epithelial cells appears to be via the death receptor (Fas) pathway The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A258-D |
0.565 |
|
2006 |
Simbulan-Rosenthal CM, Ray R, Benton B, Soeda E, Daher A, Anderson D, Smith WJ, Rosenthal DS. Calmodulin mediates sulfur mustard toxicity in human keratinocytes. Toxicology. 227: 21-35. PMID 16935404 DOI: 10.1016/J.Tox.2006.06.019 |
0.707 |
|
2006 |
Simbulan-Rosenthal CM, Daher A, Trabosh V, Chen WC, Gerstel D, Soeda E, Rosenthal DS. Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes. Oncogene. 25: 3649-60. PMID 16449966 DOI: 10.1038/Sj.Onc.1209407 |
0.724 |
|
2006 |
Daher A, Simbulan-Rosenthal CM, Rosenthal DS. Apoptosis induced by ultraviolet B in HPV-immortalized human keratinocytes requires caspase-9 and is death receptor independent. Experimental Dermatology. 15: 23-34. PMID 16364028 DOI: 10.1111/J.0906-6705.2005.00384.X |
0.691 |
|
2005 |
Simbulan-Rosenthal CM, Trabosh V, Velarde A, Chou FP, Daher A, Tenzin F, Tokino T, Rosenthal DS. Id2 protein is selectively upregulated by UVB in primary, but not in immortalized human keratinocytes and inhibits differentiation. Oncogene. 24: 5443-58. PMID 16007217 DOI: 10.1038/Sj.Onc.1208709 |
0.624 |
|
2003 |
Simbulan-Rosenthal CM, Rosenthal DS, Luo R, Samara R, Espinoza LA, Hassa PO, Hottiger MO, Smulson ME. PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase. Oncogene. 22: 8460-71. PMID 14627987 DOI: 10.1038/Sj.Onc.1206897 |
0.343 |
|
2003 |
Rosenthal DS, Velena A, Chou FP, Schlegel R, Ray R, Benton B, Anderson D, Smith WJ, Simbulan-Rosenthal CM. Expression of dominant-negative Fas-associated death domain blocks human keratinocyte apoptosis and vesication induced by sulfur mustard. The Journal of Biological Chemistry. 278: 8531-40. PMID 12482751 DOI: 10.1074/jbc.M209549200 |
0.574 |
|
2002 |
Trofimova I, Dimtchev A, Jung M, Rosenthal D, Smulson M, Dritschilo A, Soldatenkov V. Gene therapy for prostate cancer by targeting poly(ADP-ribose) polymerase Cancer Research. 62: 6879-6883. PMID 12460902 |
0.32 |
|
2002 |
Simbulan-Rosenthal CM, Velena A, Veldman T, Schlegel R, Rosenthal DS. HPV-16 E6/7 immortalization sensitizes human keratinocytes to ultraviolet B by altering the pathway from caspase-8 to caspase-9-dependent apoptosis. The Journal of Biological Chemistry. 277: 24709-16. PMID 11976323 DOI: 10.1074/Jbc.M200281200 |
0.497 |
|
2001 |
Rosenthal DS, Simbulan-Rosenthal CM, Liu WF, Velena A, Anderson D, Benton B, Wang ZQ, Smith W, Ray R, Smulson ME. PARP determines the mode of cell death in skin fibroblasts, but not keratinocytes, exposed to sulfur mustard. The Journal of Investigative Dermatology. 117: 1566-73. PMID 11886524 DOI: 10.1046/J.0022-202X.2001.01578.X |
0.529 |
|
2001 |
Rosenthal DS, Simbulan-Rosenthal CM, Liu WF, Stoica BA, Smulson ME. Mechanisms of JP-8 jet fuel cell toxicity. II. Induction of necrosis in skin fibroblasts and keratinocytes and modulation of levels of Bcl-2 family members. Toxicology and Applied Pharmacology. 171: 107-16. PMID 11222086 DOI: 10.1006/Taap.2000.9109 |
0.542 |
|
2001 |
Stoica BA, Boulares AH, Rosenthal DS, Iyer S, Hamilton ID, Smulson ME. Mechanisms of JP-8 jet fuel toxicity. I. Induction of apoptosis in rat lung epithelial cells. Toxicology and Applied Pharmacology. 171: 94-106. PMID 11222085 DOI: 10.1006/Taap.2000.9108 |
0.53 |
|
2001 |
Simbulan-Rosenthal CM, Rosenthal DS, Luo R, Li JH, Zhang J, Smulson ME. Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy. Nucleic Acids Research. 29: 841-9. PMID 11160908 DOI: 10.1093/Nar/29.3.841 |
0.353 |
|
2001 |
Rosenthal DS, Simbulan-Rosenthal CM, Liu WF, Smulson ME. Poly(ADP-ribose) polymerase and aging Advances in Cell Aging and Gerontology. 4: 113-133. DOI: 10.1016/S1566-3124(01)04030-5 |
0.318 |
|
2000 |
Rosenthal DS, Simbulan-Rosenthal CM, Iyer S, Smith WJ, Ray R, Smulson ME. Calmodulin, poly(ADP-ribose)polymerase and p53 are targets for modulating the effects of sulfur mustard. Journal of Applied Toxicology : Jat. 20: S43-9. PMID 11428642 DOI: 10.1002/1099-1263(200012)20:1+<::Aid-Jat691>3.0.Co;2-S |
0.567 |
|
1999 |
Simbulan-Rosenthal CM, Rosenthal DS, Luo R, Smulson ME. Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol alpha expression during early S phase. Oncogene. 18: 5015-23. PMID 10490838 DOI: 10.1038/Sj.Onc.1202900 |
0.361 |
|
1999 |
Simbulan-Rosenthal CM, Rosenthal DS, Iyer S, Boulares H, Smulson ME. Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication. Molecular and Cellular Biochemistry. 193: 137-48. PMID 10331650 DOI: 10.1007/978-1-4419-8740-2_20 |
0.423 |
|
1998 |
Simbulan-Rosenthal CM, Rosenthal DS, Ding R, Bhatia K, Smulson ME. Prolongation of the p53 response to DNA strand breaks in cells depleted of PARP by antisense RNA expression. Biochemical and Biophysical Research Communications. 253: 864-8. PMID 9918821 DOI: 10.1006/Bbrc.1998.9792 |
0.301 |
|
1998 |
Stöppler H, Stöppler MC, Johnson E, Simbulan-Rosenthal CM, Smulson ME, Iyer S, Rosenthal DS, Schlegel R. The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosis. Oncogene. 17: 1207-14. PMID 9771963 DOI: 10.1038/Sj.Onc.1202053 |
0.434 |
|
1998 |
Rosenthal DS, Simbulan-Rosenthal CM, Iyer S, Spoonde A, Smith W, Ray R, Smulson ME. Sulfur mustard induces markers of terminal differentiation and apoptosis in keratinocytes via a Ca2+-calmodulin and caspase-dependent pathway. The Journal of Investigative Dermatology. 111: 64-71. PMID 9665388 DOI: 10.1046/J.1523-1747.1998.00250.X |
0.564 |
|
1998 |
Simbulan-Rosenthal CM, Rosenthal DS, Boulares AH, Hickey RJ, Malkas LH, Coll JM, Smulson ME. Regulation of the expression or recruitment of components of the DNA synthesome by poly(ADP-ribose) polymerase. Biochemistry. 37: 9363-70. PMID 9649317 DOI: 10.1021/bi9731089 |
0.303 |
|
1998 |
Simbulan-Rosenthal CM, Rosenthal DS, Iyer S, Boulares AH, Smulson ME. Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis. The Journal of Biological Chemistry. 273: 13703-12. PMID 9593711 DOI: 10.1074/jbc.273.22.13703 |
0.564 |
|
1998 |
Cuvillier O, Rosenthal DS, Smulson ME, Spiegel S. Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. The Journal of Biological Chemistry. 273: 2910-6. PMID 9446602 DOI: 10.1074/Jbc.273.5.2910 |
0.544 |
|
1997 |
Rosenthal DS, Ding R, Simbulan-Rosenthal CMG, Vaillancourt JP, Nicholson DW, Smulson M. Intact cell evidence for the early synthesis, and subsequent late apopain-mediated suppression, of poly(ADP-ribose) during apoptosis Experimental Cell Research. 232: 313-321. PMID 9168807 DOI: 10.1006/Excr.1997.3536 |
0.518 |
|
1995 |
Rosenthal DS, Shima TB, Celli G, De Luca LM, Smulson ME. Engineered human skin model using poly(ADP-ribose) polymerase antisense expression shows a reduced response to DNA damage. The Journal of Investigative Dermatology. 105: 38-43. PMID 7615974 DOI: 10.1111/1523-1747.Ep12312525 |
0.33 |
|
1995 |
Berger A, Rosenthal D, Spiegel S. Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1. Proceedings of the National Academy of Sciences of the United States of America. 92: 5885-9. PMID 7597047 DOI: 10.1073/Pnas.92.13.5885 |
0.411 |
|
1995 |
Rosenthal DS, Simbulan CM, Smulson ME. Model systems for the study of the role of PADPRP in essential biological processes. Biochimie. 77: 439-43. PMID 7578426 DOI: 10.1016/0300-9084(96)88157-0 |
0.334 |
|
1994 |
Rosenthal D, Hong T, Cherney B, Zhang S, Shima T, Danielsen M, Smulson M. Expression and characterization of a fusion protein between the catalytic domain of poly(ADP-ribose) polymerase and the DNA binding domain of the glucocorticoid receptor Biochemical and Biophysical Research Communications. 202: 880-887. PMID 8048960 DOI: 10.1006/Bbrc.1994.2012 |
0.365 |
|
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