Rafael Fridman - Publications

Affiliations: 
Pathology Wayne State University, Detroit, MI, United States 
Area:
Biochemistry

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 A Romero C, Mathew S, Wasinski B, Reed B, Brody A, Dawood R, Twiner MJ, McNaughton CD, Fridman R, Flack JM, Carretero OA, Levy PD. Angiotensin-converting enzyme inhibitors increase anti-fibrotic biomarkers in African Americans with left ventricular hypertrophy. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 33694311 DOI: 10.1111/jch.14206  0.346
2020 Ruggeri JM, Franco-Barraza J, Sohail A, Zhang Y, Long D, Pasca di Magliano M, Cukierman E, Fridman R, Crawford HC. Discoidin Domain Receptor 1 (DDR1) is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma. The American Journal of Pathology. PMID 32339496 DOI: 10.1016/J.Ajpath.2020.03.020  0.342
2020 Wasinski B, Sohail A, Bonfil RD, Kim S, Saliganan A, Polin L, Bouhamdan M, Kim HC, Prunotto M, Fridman R. Discoidin Domain Receptors, DDR1b and DDR2, Promote Tumour Growth within Collagen but DDR1b Suppresses Experimental Lung Metastasis in HT1080 Xenografts. Scientific Reports. 10: 2309. PMID 32047176 DOI: 10.1038/S41598-020-59028-W  0.303
2020 Warner RB, Najy AJ, Jung YS, Fridman R, Kim S, Kim HC. Establishment of Structure-Function Relationship of Tissue Inhibitor of Metalloproteinase-1 for Its Interaction with CD63: Implication for Cancer Therapy. Scientific Reports. 10: 2099. PMID 32034211 DOI: 10.1038/S41598-020-58964-X  0.582
2019 Sarkar A, Sohail A, Dong J, Prunotto M, Shinki K, Fridman R, Hoffmann PM. Live cell measurements of interaction forces and binding kinetics between Discoidin domain receptor 1 and collagen I with atomic force microscopy. Biochimica Et Biophysica Acta. General Subjects. PMID 31351093 DOI: 10.1016/J.Bbagen.2019.07.011  0.33
2019 Reger de Moura C, Battistella M, Sohail A, Caudron A, Feugeas JP, Podgorniak MP, Pages C, Mazouz Dorval S, Marco O, Menashi S, Fridman R, Lebbé C, Mourah S, Jouenne F. Discoidin Domain Receptors: A promising target in melanoma. Pigment Cell & Melanoma Research. PMID 31271515 DOI: 10.1111/Pcmr.12809  0.342
2018 Pahwa S, Bhowmick M, Amar S, Cao J, Strongin AY, Fridman R, Weiss SJ, Fields GB. Characterization and regulation of MT1-MMP cell surface-associated activity. Chemical Biology & Drug Design. PMID 30480376 DOI: 10.1111/Cbdd.13450  0.675
2018 Yeung DA, Shanker N, Sohail A, Weiss BA, Wang C, Wellmerling J, Das S, Ganju RK, Miller JLC, Herr AB, Fridman R, Agarwal G. Clustering, Spatial Distribution and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen Type I. Journal of Molecular Biology. PMID 30458172 DOI: 10.1016/J.Jmb.2018.11.015  0.315
2017 Fridman R. Preface - Matrix Metalloproteinases. Biochimica Et Biophysica Acta. PMID 28739264 DOI: 10.1016/j.bbamcr.2017.07.007  0.578
2016 Dong J, Sarkar A, Suhail A, Fridman R, Hoffmann P. SU-F-SPS-08: Measuring the Interaction Of DDR Cell Receptors and Extracellular Matrix Collagen in Prostate Cells. Medical Physics. 43: 3352. PMID 28046999 DOI: 10.1118/1.4955683  0.408
2016 Wang C, Yeung D, Wellerming J, Herr A, Miller J, Fridman R, Agarwal G. Role of DDR2 ECD Oligomerization in Binding to Collagen Microscopy and Microanalysis. 22: 1126-1127. DOI: 10.1017/S1431927616006474  0.338
2015 Knapinska AM, Dreymuller D, Ludwig A, Smith L, Golubkov V, Sohail A, Fridman R, Giulianotti M, LaVoi TM, Houghten RA, Fields GB, Minond D. SAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes. Journal of Medicinal Chemistry. 58: 5808-24. PMID 26192023 DOI: 10.1021/Acs.Jmedchem.5B00354  0.344
2014 D'Angelo RC, Liu XW, Najy AJ, Jung YS, Won J, Chai KX, Fridman R, Kim HR. TIMP-1 via TWIST1 induces EMT phenotypes in human breast epithelial cells. Molecular Cancer Research : McR. 12: 1324-33. PMID 24895412 DOI: 10.1158/1541-7786.Mcr-14-0105  0.418
2013 Dilly AK, Ekambaram P, Guo Y, Cai Y, Tucker SC, Fridman R, Kandouz M, Honn KV. Platelet-type 12-lipoxygenase induces MMP9 expression and cellular invasion via activation of PI3K/Akt/NF-κB. International Journal of Cancer. Journal International Du Cancer. 133: 1784-91. PMID 23526143 DOI: 10.1002/Ijc.28165  0.498
2013 Fu HL, Sohail A, Valiathan RR, Wasinski BD, Kumarasiri M, Mahasenan KV, Bernardo MM, Tokmina-Roszyk D, Fields GB, Mobashery S, Fridman R. Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases. The Journal of Biological Chemistry. 288: 12114-29. PMID 23519472 DOI: 10.1074/Jbc.M112.409599  0.654
2013 Nangia-Makker P, Raz T, Tait L, Shekhar MPV, Li H, Balan V, Makker H, Fridman R, Maddipati K, Raz A. Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases Cancer Biology and Therapy. 14: 417-427. PMID 23380593 DOI: 10.4161/cbt.23762  0.586
2012 Jung YS, Liu XW, Chirco R, Warner RB, Fridman R, Kim HR. TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain. Plos One. 7: e38773. PMID 22701711 DOI: 10.1371/Journal.Pone.0038773  0.749
2012 Toth M, Sohail A, Fridman R. Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography. Methods in Molecular Biology (Clifton, N.J.). 878: 121-35. PMID 22674130 DOI: 10.1007/978-1-61779-854-2_8  0.618
2012 Fridman R, Benton G, Aranoutova I, Kleinman HK, Bonfil RD. Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection. Nature Protocols. 7: 1138-44. PMID 22596226 DOI: 10.1038/Nprot.2012.053  0.337
2012 Valiathan RR, Marco M, Leitinger B, Kleer CG, Fridman R. Discoidin domain receptor tyrosine kinases: new players in cancer progression. Cancer Metastasis Reviews. 31: 295-321. PMID 22366781 DOI: 10.1007/S10555-012-9346-Z  0.368
2011 Sohail A, Marco M, Zhao H, Shi Q, Merriman S, Mobashery S, Fridman R. Characterization of the dimerization interface of membrane type 4 (MT4)-matrix metalloproteinase. The Journal of Biological Chemistry. 286: 33178-89. PMID 21828052 DOI: 10.1074/Jbc.M111.253369  0.755
2011 Dobson M, Ramakrishnan G, Ma S, Kaplun L, Balan V, Fridman R, Tzivion G. Bimodal regulation of FoxO3 by AKT and 14-3-3. Biochimica Et Biophysica Acta. 1813: 1453-64. PMID 21621563 DOI: 10.1016/J.Bbamcr.2011.05.001  0.65
2011 Nuti E, Casalini F, Santamaria S, Gabelloni P, Bendinelli S, Da Pozzo E, Costa B, Marinelli L, La Pietra V, Novellino E, Margarida Bernardo M, Fridman R, Da Settimo F, Martini C, Rossello A. Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors European Journal of Medicinal Chemistry. 46: 2617-2629. PMID 21514700 DOI: 10.1016/J.Ejmech.2011.03.033  0.73
2010 Mayyas E, Bernardo M, Runyan L, Sohail A, Subba-Rao V, Pantea M, Fridman R, Hoffmann PM. Dissociation kinetics of an enzyme-inhibitor system using single-molecule force measurements. Biomacromolecules. 11: 3352-8. PMID 20973496 DOI: 10.1021/Bm100844X  0.347
2010 Kim S, Huang W, Mottillo EP, Sohail A, Ham YA, Conley-Lacomb MK, Kim CJ, Tzivion G, Kim HR, Wang S, Chen YQ, Fridman R. Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP. Biochimica Et Biophysica Acta. 1803: 1287-97. PMID 20620173 DOI: 10.1016/J.Bbamcr.2010.06.011  0.809
2010 Sabbota AL, Kim HR, Zhe X, Fridman R, Bonfil RD, Cher ML. Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration. Cancer Research. 70: 5558-66. PMID 20551048 DOI: 10.1158/0008-5472.Can-09-4416  0.659
2010 Fortin CF, Sohail A, Sun Q, McDonald PP, Fridman R, Fülöp T. MT6-MMP is present in lipid rafts and faces inward in living human PMNs but translocates to the cell surface during neutrophil apoptosis. International Immunology. 22: 637-49. PMID 20501611 DOI: 10.1093/Intimm/Dxq048  0.793
2010 Fridman R. Matrix metalloproteinases. Biochimica Et Biophysica Acta. 1803: 1-2. PMID 20159302 DOI: 10.1016/j.bbamcr.2010.01.016  0.578
2009 Gooyit M, Lee M, Hesek D, Boggess B, Oliver AG, Fridman R, Mobashery S, Chang M. Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors. Chemical Biology & Drug Design. 74: 535-46. PMID 19824893 DOI: 10.1111/J.1747-0285.2009.00898.X  0.603
2009 Forbes C, Shi Q, Fisher JF, Lee M, Hesek D, Llarrull LI, Toth M, Gossing M, Fridman R, Mobashery S. Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases. Chemical Biology & Drug Design. 74: 527-34. PMID 19807733 DOI: 10.1111/J.1747-0285.2009.00881.X  0.529
2009 Lee M, Celenza G, Boggess B, Blase J, Shi Q, Toth M, Bernardo MM, Wolter WR, Suckow MA, Hesek D, Noll BC, Fridman R, Mobashery S, Chang M. A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition. Chemical Biology & Drug Design. 73: 189-202. PMID 19207421 DOI: 10.1111/J.1747-0285.2008.00750.X  0.395
2008 Zhao H, Sohail A, Sun Q, Shi Q, Kim S, Mobashery S, Fridman R. Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25). The Journal of Biological Chemistry. 283: 35023-32. PMID 18936094 DOI: 10.1074/Jbc.M806553200  0.843
2008 Bonfil RD, Fridman R, Mobashery S, Cher ML. Are matrix metalloproteinases relevant therapeutic targets for prostate cancer bone metastasis? Current Oncology (Toronto, Ont.). 15: 188-92. PMID 18769612 DOI: 10.3747/Co.V15I4.216  0.39
2008 Xu D, Suenaga N, Edelmann MJ, Fridman R, Muschel RJ, Kessler BM. Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach. Molecular & Cellular Proteomics : McP. 7: 2215-28. PMID 18596065 DOI: 10.1074/Mcp.M800095-Mcp200  0.689
2008 Cho JA, Osenkowski P, Zhao H, Kim S, Toth M, Cole K, Aboukameel A, Saliganan A, Schuger L, Bonfil RD, Fridman R. The inactive 44-kDa processed form of membrane type 1 matrix metalloproteinase (MT1-MMP) enhances proteolytic activity via regulation of endocytosis of active MT1-MMP. The Journal of Biological Chemistry. 283: 17391-405. PMID 18413312 DOI: 10.1074/Jbc.M708943200  0.888
2008 Sohail A, Sun Q, Zhao H, Bernardo MM, Cho JA, Fridman R. MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer. Cancer Metastasis Reviews. 27: 289-302. PMID 18286233 DOI: 10.1007/S10555-008-9129-8  0.801
2007 Nangia-Makker P, Raz T, Tait L, Hogan V, Fridman R, Raz A. Galectin-3 cleavage: a novel surrogate marker for matrix metalloproteinase activity in growing breast cancers. Cancer Research. 67: 11760-8. PMID 18089806 DOI: 10.1158/0008-5472.Can-07-3233  0.674
2007 Rosenblum G, Meroueh S, Toth M, Fisher JF, Fridman R, Mobashery S, Sagi I. Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: Challenging the cysteine switch dogma Journal of the American Chemical Society. 129: 13566-13574. PMID 17929919 DOI: 10.1021/Ja073941L  0.565
2007 Lee M, Villegas-Estrada A, Celenza G, Boggess B, Toth M, Kreitinger G, Forbes C, Fridman R, Mobashery S, Chang M. Metabolism of a highly selective gelatinase inhibitor generates active metabolite. Chemical Biology & Drug Design. 70: 371-82. PMID 17927722 DOI: 10.1111/J.1747-0285.2007.00577.X  0.421
2007 Bonfil RD, Chinni S, Fridman R, Kim HR, Cher ML. Proteases, growth factors, chemokines, and the microenvironment in prostate cancer bone metastasis. Urologic Oncology. 25: 407-11. PMID 17826661 DOI: 10.1016/J.Urolonc.2007.05.008  0.382
2007 Wu YI, Munshi HG, Snipas SJ, Salvesen GS, Fridman R, Stack MS. Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking. The Biochemical Journal. 407: 171-7. PMID 17650075 DOI: 10.1042/Bj20070552  0.632
2007 Bonfil RD, Dong Z, Trindade Filho JC, Sabbota A, Osenkowski P, Nabha S, Yamamoto H, Chinni SR, Zhao H, Mobashery S, Vessella RL, Fridman R, Cher ML. Prostate cancer-associated membrane type 1-matrix metalloproteinase: A pivotal role in bone response and intraosseous tumor growth American Journal of Pathology. 170: 2100-2111. PMID 17525276 DOI: 10.2353/Ajpath.2007.060720  0.863
2007 Sun Q, Weber CR, Sohail A, Bernardo MM, Toth M, Zhao H, Turner JR, Fridman R. MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties. The Journal of Biological Chemistry. 282: 21998-2010. PMID 17513868 DOI: 10.1074/Jbc.M701737200  0.802
2007 McClung HM, Thomas SL, Osenkowski P, Toth M, Menon P, Raz A, Fridman R, Rempel SA. SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells. Neuroscience Letters. 419: 172-7. PMID 17490812 DOI: 10.1016/J.Neulet.2007.04.037  0.882
2007 Calkins CC, Dosescu J, Day NA, Ren WP, Fridman R, Sloane BF, Moin K. Functional expression of recombinant human stefin A in mammalian and bacterial cells. Protein Expression and Purification. 52: 463-71. PMID 17208452 DOI: 10.1016/J.Pep.2006.11.020  0.328
2007 Borrirukwanit K, Lafleur MA, Mercuri FA, Blick T, Price JT, Fridman R, Pereira JJ, Leardkamonkarn V, Thompson EW. The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells. Matrix Biology : Journal of the International Society For Matrix Biology. 26: 291-305. PMID 17175151 DOI: 10.1016/J.Matbio.2006.10.014  0.679
2007 Kim S, Zhao H, Ham Y, Chompootaweep N, Fridman R. Translational regulation of membrane type 3‐matrix metalloproteinase (MT3‐MMP) expression The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A648-B  0.611
2006 Toth M, Sohail A, Mobashery S, Fridman R. MT1-MMP shedding involves an ADAM and is independent of its localization in lipid rafts Biochemical and Biophysical Research Communications. 350: 377-384. PMID 17007816 DOI: 10.1016/J.Bbrc.2006.09.052  0.7
2006 Jung KK, Liu XW, Chirco R, Fridman R, Kim HR. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. The Embo Journal. 25: 3934-42. PMID 16917503 DOI: 10.1038/Sj.Emboj.7601281  0.404
2006 Hesek D, Toth M, Krchňák V, Fridman R, Mobashery S. Synthesis of an inhibitor-tethered resin for detection of active matrix metalloproteinases involved in disease Journal of Organic Chemistry. 71: 5848-5854. PMID 16872162 DOI: 10.1021/jo060058h  0.58
2006 Hesek D, Toth M, Meroueh SO, Brown S, Zhao H, Sakr W, Fridman R, Mobashery S. Design and Characterization of a Metalloproteinase Inhibitor-Tethered Resin for the Detection of Active MMPs in Biological Samples Chemistry and Biology. 13: 379-386. PMID 16632250 DOI: 10.1016/J.Chembiol.2006.01.012  0.729
2006 Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM. Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1876-82. PMID 16551873 DOI: 10.1158/1078-0432.Ccr-05-2686  0.653
2006 Taube ME, Liu XW, Fridman R, Kim HR. TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27(KIP1) protein. Oncogene. 25: 3041-8. PMID 16407831 DOI: 10.1038/sj.onc.1209336  0.345
2006 Bonfil RD, Sabbota A, Nabha S, Bernardo MM, Dong Z, Meng H, Yamamoto H, Chinni SR, Lim IT, Chang M, Filetti LC, Mobashery S, Cher ML, Fridman R. Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor. International Journal of Cancer. Journal International Du Cancer. 118: 2721-6. PMID 16381009 DOI: 10.1002/Ijc.21645  0.594
2006 Bonfil RD, Dong Z, Trindade Filho JC, Zhao H, Ossenkowski P, Nabha S, Yamamoto H, Sabbota A, Chinni S, Vessella RL, Fridman R, Cher ML. 434: Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Promotes Tumor Growth and Bone Degradation in Prostate Cancer Bone Metastasis Journal of Urology. 175: 141-141. DOI: 10.1016/S0022-5347(18)32690-9  0.692
2006 Fridman R. Metalloproteinases and cancer Cancer and Metastasis Reviews. 25: 7-8. DOI: 10.1007/S10555-006-7885-X  0.637
2005 Ikejiri M, Bernardo MM, Bonfil RD, Toth M, Chang M, Fridman R, Mobashery S. Potent mechanism-based inhibitors for matrix metalloproteinases. The Journal of Biological Chemistry. 280: 33992-4002. PMID 16046398 DOI: 10.1074/Jbc.M504303200  0.709
2005 Gu Z, Cui J, Brown S, Fridman R, Mobashery S, Strongin AY, Lipton SA. A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6401-8. PMID 16000631 DOI: 10.1523/Jneurosci.1563-05.2005  0.565
2005 Ikejiri M, Bernardo MM, Meroueh SO, Brown S, Chang M, Fridman R, Mobashery S. Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A. The Journal of Organic Chemistry. 70: 5709-12. PMID 15989356 DOI: 10.1021/Jo050339+  0.682
2005 Sosne G, Christopherson PL, Barrett RP, Fridman R. Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury. Investigative Ophthalmology & Visual Science. 46: 2388-95. PMID 15980226 DOI: 10.1167/Iovs.04-1368  0.542
2005 Osenkowski P, Meroueh SO, Pavel D, Mobashery S, Fridman R. Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing Journal of Biological Chemistry. 280: 26160-26168. PMID 15901740 DOI: 10.1074/Jbc.M414379200  0.873
2005 Krüger A, Arlt MJ, Gerg M, Kopitz C, Bernardo MM, Chang M, Mobashery S, Fridman R. Antimetastatic activity of a novel mechanism-based gelatinase inhibitor. Cancer Research. 65: 3523-6. PMID 15867341 DOI: 10.1158/0008-5472.Can-04-3570  0.663
2005 Dong Z, Bonfil RD, Chinni S, Deng X, Trindade Filho JC, Bernardo M, Vaishampayan U, Che M, Sloane BF, Sheng S, Fridman R, Cher ML. Matrix metalloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue. The American Journal of Pathology. 166: 1173-86. PMID 15793297 DOI: 10.1016/S0002-9440(10)62337-1  0.79
2005 Bourd-Boittin K, Fridman R, Fanchon S, Septier D, Goldberg M, Menashi S. Matrix metalloproteinase inhibition impairs the processing, formation and mineralization of dental tissues during mouse molar development. Experimental Cell Research. 304: 493-505. PMID 15748894 DOI: 10.1016/J.Yexcr.2004.11.024  0.724
2005 Liu XW, Taube ME, Jung KK, Dong Z, Lee YJ, Roshy S, Sloane BF, Fridman R, Kim HR. Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells from extrinsic cell death: a potential oncogenic activity of tissue inhibitor of metalloproteinase-1. Cancer Research. 65: 898-906. PMID 15705888  0.573
2005 Toth M, Osenkowski P, Hesek D, Brown S, Meroueh S, Sakr W, Mobashery S, Fridman R. Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase Biochemical Journal. 387: 497-506. PMID 15560752 DOI: 10.1042/Bj20041324  0.881
2004 Lee M, Fridman R, Mobashery S. Extracellular proteases as targets for treatment of cancer metastases Chemical Society Reviews. 33: 401-409. PMID 15354221 DOI: 10.1039/B209224G  0.575
2004 Brown S, Meroueh SO, Fridman R, Mobashery S. Quest for selectivity in inhibition of matrix metalloproteinases Current Topics in Medicinal Chemistry. 4: 1227-1238. PMID 15320723 DOI: 10.2174/1568026043387854  0.692
2004 Osenkowski P, Toth M, Fridman R. Processing, shedding, and endocytosis of membrane type 1-matrix metalloproteinase (MT1-MMP). Journal of Cellular Physiology. 200: 2-10. PMID 15137052 DOI: 10.1002/Jcp.20064  0.882
2004 Bonfil RD, Osenkowski P, Fridman R, Cher ML. Matrix metalloproteinaes and bone metastasis. Cancer Treatment and Research. 118: 173-95. PMID 15043193 DOI: 10.1007/978-1-4419-9129-4_8  0.861
2004 Zhao H, Bernardo MM, Osenkowski P, Sohail A, Pei D, Nagase H, Kashiwagi M, Soloway PD, DeClerck YA, Fridman R. Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation. The Journal of Biological Chemistry. 279: 8592-601. PMID 14681236 DOI: 10.1074/Jbc.M308708200  0.886
2004 Wu YI, Munshi HG, Sen R, Snipas SJ, Salvesen GS, Fridman R, Stack MS. Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase. The Journal of Biological Chemistry. 279: 8278-89. PMID 14670950 DOI: 10.1074/Jbc.M311870200  0.769
2003 Liu XW, Bernardo MM, Fridman R, Kim HR. Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway. The Journal of Biological Chemistry. 278: 40364-72. PMID 12904305 DOI: 10.1074/Jbc.M302999200  0.559
2003 Toth M, Chvyrkova I, Bernardo MM, Hernandez-Barrantes S, Fridman R. Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes. Biochemical and Biophysical Research Communications. 308: 386-95. PMID 12901881 DOI: 10.1016/S0006-291X(03)01405-0  0.874
2003 Cher ML, Biliran HR, Bhagat S, Meng Y, Che M, Lockett J, Abrams J, Fridman R, Zachareas M, Sheng S. Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis. Proceedings of the National Academy of Sciences of the United States of America. 100: 7847-52. PMID 12788977 DOI: 10.1073/Pnas.1331360100  0.476
2003 Fridman R, Toth M, Chvyrkova I, Meroueh SO, Mobashery S. Cell surface association of matrix metalloproteinase-9 (gelatinase B) Cancer and Metastasis Reviews. 22: 153-166. PMID 12784994 DOI: 10.1023/A:1023091214123  0.726
2003 Bernardo MM, Fridman R. TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP. The Biochemical Journal. 374: 739-45. PMID 12755684 DOI: 10.1042/BJ20030557  0.725
2003 Fridman R. Surface association of secreted matrix metalloproteinases. Current Topics in Developmental Biology. 54: 75-100. PMID 12696746 DOI: 10.1016/S0070-2153(03)54005-4  0.733
2003 Rosenblum G, Meroueh SO, Kleifeld O, Brown S, Singson SP, Fridman R, Mobashery S, Sagi I. Structural basis for potent slow binding inhibition of human matrix metalloproteinase-2 (MMP-2) Journal of Biological Chemistry. 278: 27009-27015. PMID 12679334 DOI: 10.1074/Jbc.M301139200  0.602
2002 Kotra LP, Zhang L, Fridman R, Orlando R, Mobashery S. N-Glycosylation pattern of the zymogenic form of human matrix metalloproteinase-9. Bioorganic Chemistry. 30: 356-70. PMID 12485595 DOI: 10.1016/S0045-2068(02)00501-1  0.681
2002 Hernandez-Barrantes S, Bernardo M, Toth M, Fridman R. Regulation of membrane type-matrix metalloproteinases. Seminars in Cancer Biology. 12: 131-8. PMID 12027585 DOI: 10.1006/Scbi.2001.0421  0.862
2002 Toth M, Hernandez-Barrantes S, Osenkowski P, Bernardo MM, Gervasi DC, Shimura Y, Meroueh O, Kotra LP, Gálvez BG, Arroyo AG, Mobashery S, Fridman R. Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme. The Journal of Biological Chemistry. 277: 26340-50. PMID 12004057 DOI: 10.1074/Jbc.M200655200  0.837
2002 Bernardo MM, Brown S, Li ZH, Fridman R, Mobashery S. Design, synthesis, and characterization of potent, slow-binding inhibitors that are selective for gelatinases. The Journal of Biological Chemistry. 277: 11201-7. PMID 11790786 DOI: 10.1074/Jbc.M111021200  0.674
2002 Nemeth JA, Yousif R, Herzog M, Che M, Upadhyay J, Shekarriz B, Bhagat S, Mullins C, Fridman R, Cher ML. Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis. Journal of the National Cancer Institute. 94: 17-25. PMID 11773278 DOI: 10.1093/Jnci/94.1.17  0.506
2001 Lengyel E, Schmalfeldt B, Konik E, Späthe K, Härting K, Fenn A, Berger U, Fridman R, Schmitt M, Prechtel D, Kuhn W. Expression of latent matrix metalloproteinase 9 (MMP-9) predicts survival in advanced ovarian cancer. Gynecologic Oncology. 82: 291-8. PMID 11531282 DOI: 10.1006/Gyno.2001.6243  0.697
2001 Dong Z, Nemeth JA, Cher ML, Palmer KC, Bright RC, Fridman R. Differential regulation of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2 expression in co-cultures of prostate cancer and stromal cells. International Journal of Cancer. 93: 507-15. PMID 11477554 DOI: 10.1002/Ijc.1358  0.768
2001 Kotra LP, Cross JB, Shimura Y, Fridman R, Schlegel HB, Mobashery S. Insight into the complex and dynamic process of activation of matrix metalloproteinases. Journal of the American Chemical Society. 123: 3108-13. PMID 11457021 DOI: 10.1021/ja001896a  0.454
2001 Kleifeld O, Kotra LP, Gervasi DC, Brown S, Bernardo MM, Fridman R, Mobashery S, Sagi I. X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor. comparison with the latent and active forms of the enzyme. The Journal of Biological Chemistry. 276: 17125-31. PMID 11278946 DOI: 10.1074/Jbc.M011604200  0.671
2001 Hernandez-Barrantes S, Shimura Y, Soloway PD, Sang QA, Fridman R. Differential roles of TIMP-4 and TIMP-2 in pro-MMP-2 activation by MT1-MMP. Biochemical and Biophysical Research Communications. 281: 126-30. PMID 11178970 DOI: 10.1006/Bbrc.2001.4323  0.875
2001 Puyraimond A, Fridman R, Lemesle M, Arbeille B, Menashi S. MMP-2 colocalizes with caveolae on the surface of endothelial cells. Experimental Cell Research. 262: 28-36. PMID 11120602 DOI: 10.1006/Excr.2000.5069  0.73
2001 Toth M, Bernardo MM, Gervasi DC, Soloway PD, Wang Z, Bigg HF, Overall CM, DeClerck YA, Tschesche H, Cher ML, Brown S, Mobashery S, Fridman R. Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2. The Journal of Biological Chemistry. 275: 41415-23. PMID 10998420 DOI: 10.1074/Jbc.M006871200  0.722
2000 Dong Z, Ghabrial M, Katar M, Fridman R, Berk RS. Membrane-type matrix metalloproteinases in mice intracorneally infected with Pseudomonas aeruginosa. Investigative Ophthalmology & Visual Science. 41: 4189-94. PMID 11095614  0.657
2000 Hernandez-Barrantes S, Toth M, Bernardo MM, Yurkova M, Gervasi DC, Raz Y, Sang QA, Fridman R. Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation. The Journal of Biological Chemistry. 275: 12080-9. PMID 10766841 DOI: 10.1074/Jbc.275.16.12080  0.878
2000 Olson MW, Bernardo MM, Pietila M, Gervasi DC, Toth M, Kotra LP, Massova I, Mobashery S, Fridman R. Characterization of the monomeric and dimeric forms of latent and active matrix metalloproteinase-9. Differential rates for activation by stromelysin 1. The Journal of Biological Chemistry. 275: 2661-8. PMID 10644727 DOI: 10.1074/Jbc.275.4.2661  0.72
1999 Upadhyay J, Shekarriz B, Nemeth JA, Dong Z, Cummings GD, Fridman R, Sakr W, Grignon DJ, Cher ML. Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 4105-10. PMID 10632347  0.738
1999 Toth M, Sado Y, Ninomiya Y, Fridman R. Biosynthesis of alpha2(IV) and alpha1(IV) chains of collagen IV and interactions with matrix metalloproteinase-9. Journal of Cellular Physiology. 180: 131-9. PMID 10362026 DOI: 10.1002/(Sici)1097-4652(199907)180:1<131::Aid-Jcp15>3.0.Co;2-S  0.422
1998 Olson MW, Toth M, Gervasi DC, Sado Y, Ninomiya Y, Fridman R. High affinity binding of latent matrix metalloproteinase-9 to the alpha2(IV) chain of collagen IV. The Journal of Biological Chemistry. 273: 10672-81. PMID 9553130 DOI: 10.1074/Jbc.273.17.10672  0.656
1998 Menashi S, Dehem M, Souliac I, Legrand Y, Fridman R. Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells. International Journal of Cancer. 75: 259-65. PMID 9462717 DOI: 10.1002/(Sici)1097-0215(19980119)75:2<259::Aid-Ijc15>3.0.Co;2-8  0.706
1998 Massova I, Kotra LP, Fridman R, Mobashery S. Matrix metalloproteinases: structures, evolution, and diversification The Faseb Journal. 12: 1075-1095. DOI: 10.1096/Fasebj.12.12.1075  0.599
1997 Olson MW, Gervasi DC, Mobashery S, Fridman R. Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2. The Journal of Biological Chemistry. 272: 29975-83. PMID 9368077 DOI: 10.1074/Jbc.272.47.29975  0.656
1997 Kernacki KA, Fridman R, Hazlett LD, Lande MA, Berk RS. In vivo characterization of host and bacterial protease expression during Pseudomonas aeruginosa corneal infections in naive and immunized mice Current Eye Research. 16: 289-297. PMID 9134316 DOI: 10.1076/Ceyr.16.4.289.10686  0.306
1997 Kondapaka SB, Fridman R, Reddy KB. Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells. International Journal of Cancer. 70: 722-6. PMID 9096655 DOI: 10.1002/(Sici)1097-0215(19970317)70:6<722::Aid-Ijc15>3.0.Co;2-B  0.58
1997 Visscher DW, Sarkar FH, Kusinic TC, Fridman R, Banerjee M, Reddy KB. Phospholipase C-? Immunostaining in Human Breast Carcinoma: Clinical Significance and Correlations with Protease and Growth-Factor Receptor Species The Breast Journal. 3: 350-356. DOI: 10.1111/J.1524-4741.1997.Tb00192.X  0.47
1997 Massova I, Fridman R, Mobashery S. Structural Insights into the Catalytic Domains of Human Matrix Metalloprotease-2 and Human Matrix Metalloprotease-9: Implications for Substrate Specificities Journal of Molecular Modeling. 3: 17-30. DOI: 10.1007/S008940050021  0.715
1996 Ren WP, Fridman R, Zabrecky JR, Morris LD, Day NA, Sloane BF. Expression of functional recombinant human procathepsin B in mammalian cells. The Biochemical Journal. 319: 793-800. PMID 8920982 DOI: 10.1042/Bj3190793  0.316
1996 Gervasi DC, Raz A, Dehem M, Yang M, Kurkinen M, Fridman R. Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells. Biochemical and Biophysical Research Communications. 228: 530-8. PMID 8920947 DOI: 10.1006/Bbrc.1996.1694  0.67
1996 Levi E, Fridman R, Miao HQ, Ma YS, Yayon A, Vlodavsky I. Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1. Proceedings of the National Academy of Sciences of the United States of America. 93: 7069-74. PMID 8692946 DOI: 10.1073/Pnas.93.14.7069  0.647
1995 Menashi S, Vlodavsky I, Ishai-Michaeli R, Legrand Y, Fridman R. The extracellular matrix produced by bovine corneal endothelial cells contains progelatinase A. Febs Letters. 361: 61-4. PMID 7890041 DOI: 10.1016/0014-5793(95)00125-S  0.626
1995 Belloc C, Lu H, Soria C, Fridman R, Legrand Y, Menashi S. The effect of platelets on invasiveness and protease production of human mammary tumor cells. International Journal of Cancer. 60: 413-7. PMID 7829253 DOI: 10.1002/Ijc.2910600324  0.39
1994 Hoyhtya M, Fridman R, Komarek D, Porter-Jordan K, Stetler-Stevenson WG, Liotta LA, Liang CM. Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies International Journal of Cancer. 56: 500-505. PMID 8112886 DOI: 10.1002/ijc.2910560408  0.567
1994 Menashi S, Fridman R, Desrivieres S, Lu H, Legrand Y, Soria C. Regulation of 92-kDa gelatinase B activity in the extracellular matrix by tissue kallikrein. Annals of the New York Academy of Sciences. 732: 466-8. PMID 7978840 DOI: 10.1111/J.1749-6632.1994.Tb24787.X  0.487
1994 Ochieng J, Fridman R, Nangia-Makker P, Kleiner DE, Liotta LA, Stetler-Stevenson WG, Raz A. Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9. Biochemistry. 33: 14109-14. PMID 7947821 DOI: 10.1021/Bi00251A020  0.573
1994 Visscher DW, Hoyhtya M, Ottosen SK, Liang CM, Sarkar FH, Crissman JD, Fridman R. Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence International Journal of Cancer. 59: 339-344. PMID 7927938 DOI: 10.1002/Ijc.2910590308  0.677
1993 Fridman R, Bird RE, Hoyhtya M, Oelkuct M, Komarek D, Liang CM, Berman ML, Liotta LA, Stetler-Stevenson WG, Fuerst TR. Expression of human recombinant 72 kDa gelatinase and tissue inhibitor of metalloproteinase-2 (TIMP-2): Characterization of complex and free enzyme Biochemical Journal. 289: 411-416. PMID 8380993 DOI: 10.1042/Bj2890411  0.463
1993 Schnaper HW, Grant DS, Stetler-Stevenson WG, Fridman R, D'Orazi G, Murphy AN, Bird RE, Hoythya M, Fuerst TR, French DL, Quigley JP, Kleinman HK. Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro Journal of Cellular Physiology. 156: 235-246. PMID 8344982 DOI: 10.1002/Jcp.1041560204  0.416
1993 Liebman JM, Burbelo PD, Yamada Y, Fridman R, Kleinman HK. Altered expression of basement-membrane components and collagenases in ascitic xenografts of OVCAR-3 ovarian cancer cells. International Journal of Cancer. Journal International Du Cancer. 55: 102-9. PMID 8344742 DOI: 10.1002/Ijc.2910550119  0.429
1992 Sweeney TM, Kibbey MC, Zain M, Fridman R, Kleinman HK. Basement membrane and the SIKVAV laminin-derived peptide promote tumor growth and metastases. Cancer Metastasis Reviews. 10: 245-54. PMID 1764767 DOI: 10.1007/Bf00050795  0.307
1992 Fridman R, Sweeney TM, Zain M, Martin GR, Kleinman HK. Malignant transformation of NIH-3T3 cells after subcutaneous co-injection with a reconstituted basement membrane (matrigel). International Journal of Cancer. Journal International Du Cancer. 51: 740-4. PMID 1319408 DOI: 10.1002/Ijc.2910510513  0.326
1992 Grant DS, Kinsella JL, Fridman R, Auerbach R, Piasecki BA, Yamada Y, Zain M, Kleinman HK. Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo Journal of Cellular Physiology. 153: 614-625. PMID 1280280 DOI: 10.1002/Jcp.1041530324  0.343
1991 Kubota S, Fridman R, Yamada Y. Transforming growth factor-beta suppresses the invasiveness of human fibrosarcoma cells in vitro by increasing expression of tissue inhibitor of metalloprotease. Biochemical and Biophysical Research Communications. 176: 129-36. PMID 1850251 DOI: 10.1016/0006-291X(91)90899-I  0.351
1991 Fridman R, Kibbey MC, Royce LS, Zain M, Sweeney M, Jicha DL, Yannelli JR, Martin GR, Kleinman HK. Enhanced tumor growth of both primary and established human and murine tumor cells in athymic mice after coinjection with Matrigel. Journal of the National Cancer Institute. 83: 769-74. PMID 1789823 DOI: 10.1093/Jnci/83.11.769  0.303
1990 Bonfil RD, Momiki S, Fridman R, Reich R, Reddel R, Harris CC, Klein-Szanto A. Enhancement of the invasive ability of a transformed human bronchial epithelial cell line by 12-O-tetradecanoyl-phorbol-13-acetate and diacylglycerol. Carcinogenesis. 10: 2335-8. PMID 2556220 DOI: 10.1093/Carcin/10.12.2335  0.352
1990 Fridman R, Lacal JC, Reich R, Bonfil DR, Ahn CH. Differential effects of phorbol ester on the in vitro invasiveness of malignant and non-malignant human fibroblast cells. Journal of Cellular Physiology. 142: 55-60. PMID 2153689 DOI: 10.1002/Jcp.1041420108  0.418
1989 Albini A, Aukerman SL, Ogle RC, Noonan DM, Fridman R, Martin GR, Fidler IJ. The in vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants. Clinical & Experimental Metastasis. 7: 437-51. PMID 2706831 DOI: 10.1007/Bf01753664  0.35
1989 Bonfil RD, Reddel RR, Ura H, Reich R, Fridman R, Harris CC, Klein-Szanto JP. Invasive and metastatic potential of a v-Ha-ras-transformed human bronchial epithelial cell line. Journal of the National Cancer Institute. 81: 587-94. PMID 2539488 DOI: 10.1093/Jnci/81.8.587  0.312
1989 Penno MB, Passaniti A, Fridman R, Hart GW, Jordan C, Kumar S, Scott AF. In vitro galactosylation of a 110-kDa glycoprotein by an endogenous cell surface galactosyltransferase correlates with the invasiveness of adrenal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 6057-61. PMID 2527370 DOI: 10.1073/Pnas.86.16.6057  0.312
1987 Vlodavsky I, Folkman J, Sullivan R, Fridman R, Ishai-Michaeli R, Sasse J, Klagsbrun M. Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix Proceedings of the National Academy of Sciences of the United States of America. 84: 2292-2296. PMID 3470794 DOI: 10.1073/Pnas.84.8.2292  0.369
1987 Fridman R, Lider O, Naparstek Y, Fuks Z, Vlodavsky I, Cohen IR. Soluble antigen induces T lymphocytes to secrete an endoglycosidase that degrades the heparan sulfate moiety of subendothelial extracellular matrix. Journal of Cellular Physiology. 130: 85-92. PMID 2433294 DOI: 10.1002/Jcp.1041300113  0.365
1985 Fridman R, Fuks Z, Ovadia H, Vlodavsky I. Differential structural requirements for the induction of cell attachment, proliferation and differentiation by the extracellular matrix. Experimental Cell Research. 157: 181-94. PMID 2982626 DOI: 10.1016/0014-4827(85)90161-2  0.409
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