| Year |
Citation |
Score |
| 2016 |
Jones P, Storer RI, Sabnis YA, Wakenhut FM, Whitlock GA, England KS, Mukaiyama T, Dehnhardt CM, Coe JW, Kortum SW, Chrencik JE, Brown DG, Jones RM, Murphy JR, Yeoh T, et al. Design and Synthesis of a pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin. Journal of Medicinal Chemistry. PMID 27983835 DOI: 10.1021/Acs.Jmedchem.6B01634 |
0.394 |
|
| 2013 |
Liu Q, Sabnis Y, Zhao Z, Zhang T, Buhrlage SJ, Jones LH, Gray NS. Developing irreversible inhibitors of the protein kinase cysteinome. Chemistry & Biology. 20: 146-59. PMID 23438744 DOI: 10.1016/J.Chembiol.2012.12.006 |
0.366 |
|
| 2012 |
Lovering F, McDonald J, Whitlock GA, Glossop PA, Phillips C, Bent A, Sabnis Y, Ryan M, Fitz L, Lee J, Chang JS, Han S, Kurumbail R, Thorarensen A. Identification of type-II inhibitors using kinase structures. Chemical Biology & Drug Design. 80: 657-64. PMID 22759374 DOI: 10.1111/J.1747-0285.2012.01443.X |
0.315 |
|
| 2012 |
Miller DC, Lunn G, Jones P, Sabnis Y, Davies NL, Driscoll P. Investigation of the effect of molecular properties on the binding kinetics of a ligand to its biological target Medchemcomm. 3: 449. DOI: 10.1039/C2Md00270A |
0.309 |
|
| 2008 |
Muthas D, Sabnis YA, Lundborg M, Karlén A. Is it possible to increase hit rates in structure-based virtual screening by pharmacophore filtering? An investigation of the advantages and pitfalls of post-filtering. Journal of Molecular Graphics & Modelling. 26: 1237-51. PMID 18203638 DOI: 10.1016/J.Jmgm.2007.11.005 |
0.376 |
|
| 2007 |
Rönn R, Gossas T, Sabnis YA, Daoud H, Kerblom E, Danielson UH, Sandström A. Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors. Bioorganic & Medicinal Chemistry. 15: 4057-68. PMID 17449253 DOI: 10.1016/J.Bmc.2007.03.089 |
0.375 |
|
| 2007 |
Ortqvist P, Peterson SD, Kerblom E, Gossas T, Sabnis YA, Fransson R, Lindeberg G, Helena Danielson U, Karlén A, Sandström A. Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors. Bioorganic & Medicinal Chemistry. 15: 1448-74. PMID 17113777 DOI: 10.1016/J.Bmc.2006.11.003 |
0.359 |
|
| 2006 |
Wannberg J, Sabnis YA, Vrang L, Samuelsson B, Karlén A, Hallberg A, Larhed M. A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains. Bioorganic & Medicinal Chemistry. 14: 5303-15. PMID 16621572 DOI: 10.1016/J.Bmc.2006.03.045 |
0.385 |
|
| 2006 |
Rönn R, Sabnis YA, Gossas T, Akerblom E, Danielson UH, Hallberg A, Johansson A. Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3. Bioorganic & Medicinal Chemistry. 14: 544-59. PMID 16213143 DOI: 10.1016/J.Bmc.2005.08.045 |
0.355 |
|
| 2005 |
Muthas D, Nöteberg D, Sabnis YA, Hamelink E, Vrang L, Samuelsson B, Karlén A, Hallberg A. Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II. Bioorganic & Medicinal Chemistry. 13: 5371-90. PMID 16054370 DOI: 10.1016/J.Bmc.2005.06.048 |
0.528 |
|
| 2005 |
Goud PM, Sheri A, Desai PV, Watkins EB, Tekwani B, Sabnis Y, Gut J, Rosenthal PJ, Avery MA. Design, Synthesis and Evaluation of Trisubstituted Thiazoles Targeting Plasmodium Falciparum Cysteine Proteases Medicinal Chemistry Research. 14: 74-105. DOI: 10.1007/S00044-005-0126-Y |
0.608 |
|
| 2004 |
Desai PV, Patny A, Sabnis Y, Tekwani B, Gut J, Rosenthal P, Srivastava A, Avery M. Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database. Journal of Medicinal Chemistry. 47: 6609-15. PMID 15588096 DOI: 10.1021/Jm0493717 |
0.629 |
|
| 2003 |
Batra S, Sabnis YA, Rosenthal PJ, Avery MA. Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines. Bioorganic & Medicinal Chemistry. 11: 2293-9. PMID 12713840 DOI: 10.1016/S0968-0896(03)00117-2 |
0.599 |
|
| 2003 |
Sabnis YA, Desai PV, Rosenthal PJ, Avery MA. Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies. Protein Science : a Publication of the Protein Society. 12: 501-9. PMID 12592020 DOI: 10.1110/Ps.0228103 |
0.622 |
|
| 2003 |
Illapakurthy AC, Sabnis YA, Avery BA, Avery MA, Wyandt CM. Interaction of artemisinin and its related compounds with hydroxypropyl-beta-cyclodextrin in solution state: experimental and molecular-modeling studies. Journal of Pharmaceutical Sciences. 92: 649-55. PMID 12587126 DOI: 10.1002/Jps.10319 |
0.544 |
|
| 2002 |
Sabnis Y, Rosenthal PJ, Desai P, Avery MA. Homology modeling of falcipain-2: validation, de novo ligand design and synthesis of novel inhibitors. Journal of Biomolecular Structure & Dynamics. 19: 765-74. PMID 11922834 DOI: 10.1080/07391102.2002.10506783 |
0.629 |
|
| 2002 |
Avery MA, Alvim-Gaston M, Rodrigues CR, Barreiro EJ, Cohen FE, Sabnis YA, Woolfrey JR. Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies. Journal of Medicinal Chemistry. 45: 292-303. PMID 11784134 DOI: 10.1021/Jm0100234 |
0.616 |
|
| 2002 |
El Sayed KA, Orabi KY, Dunbar DC, Hamann MT, Avery MA, Sabnis YA, Mossa JS, El-Feraly FS. Transformation of lactone to lactam in sarcophine and antimalarial activity of the resulting N-substituted azasarcophines Tetrahedron. 58: 3699-3708. DOI: 10.1016/S0040-4020(02)00330-7 |
0.52 |
|
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