| Year |
Citation |
Score |
| 2024 |
Altman PX, Parren M, Sang H, Ozorowski G, Lee WH, Smider VV, Wilson IA, Ward AB, Mwangi W, Burton DR, Sok D. HIV envelope trimers and gp120 as immunogens to induce broadly neutralizing antibodies in cows. Biorxiv : the Preprint Server For Biology. PMID 38585787 DOI: 10.1101/2024.03.20.585065 |
0.419 |
|
| 2024 |
Del Moral-Sánchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Peña A, Fróes Rocha R, Ferguson J, León AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, ... ... Ozorowski G, et al. Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines. Npj Vaccines. 9: 74. PMID 38582771 DOI: 10.1038/s41541-024-00862-8 |
0.337 |
|
| 2024 |
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, et al. Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Biorxiv : the Preprint Server For Biology. PMID 38405899 DOI: 10.1101/2024.02.13.580058 |
0.379 |
|
| 2023 |
Nelson AN, Shen X, Vekatayogi S, Zhang S, Ozorowski G, Dennis M, Sewall LM, Milligan E, Davis D, Cross KA, Chen Y, van Schooten J, Eudailey J, Isaac J, Memon S, et al. Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques. Biorxiv : the Preprint Server For Biology. PMID 37986885 DOI: 10.1101/2023.11.07.565306 |
0.323 |
|
| 2023 |
Phung I, Rodrigues KA, Marina-Zárate E, Maiorino L, Pahar B, Lee WH, Melo M, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Lopez PG, ... ... Ozorowski G, et al. A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nature Communications. 14: 7107. PMID 37925510 DOI: 10.1038/s41467-023-42923-x |
0.332 |
|
| 2023 |
Ringe RP, Colin P, Ozorowski G, Allen JD, Yasmeen A, Seabright GE, Lee JH, Antanasijevic A, Rantalainen K, Ketas T, Moore JP, Ward AB, Crispin M, Klasse PJ. Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization. Plos Pathogens. 19: e1011601. PMID 37903160 DOI: 10.1371/journal.ppat.1011601 |
0.409 |
|
| 2023 |
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, et al. Focusing antibody responses to the fusion peptide in rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 37425865 DOI: 10.1101/2023.06.26.545779 |
0.35 |
|
| 2023 |
Misson Mindrebo L, Liu H, Ozorowski G, Tran Q, Woehl J, Khalek I, Smith JM, Barman S, Zhao F, Keating C, Limbo O, Verma M, Liu J, Stanfield RL, Zhu X, et al. Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216612120. PMID 37276407 DOI: 10.1073/pnas.2216612120 |
0.326 |
|
| 2023 |
Colin P, Ringe RP, Yasmeen A, Ozorowski G, Ketas TJ, Lee WH, Ward AB, Moore JP, Klasse PJ. Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization. Retrovirology. 20: 9. PMID 37244989 DOI: 10.1186/s12977-023-00624-9 |
0.363 |
|
| 2023 |
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J, Sánchez IDM, Yasmeen A, Diaz M, Aldon Y, Bijl TPL, ... ... Ozorowski G, et al. Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Reports. Medicine. 101003. PMID 37044090 DOI: 10.1016/j.xcrm.2023.101003 |
0.311 |
|
| 2023 |
Colin P, Ringe RP, Yasmeen A, Ozorowski G, Ketas TJ, Lee WH, Ward AB, Moore JP, Klasse PJ. Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization. Research Square. PMID 36865101 DOI: 10.21203/rs.3.rs-2613503/v1 |
0.382 |
|
| 2023 |
Changrob S, Halfmann PJ, Liu H, Torres JL, McGrath JJC, Ozorowski G, Li L, Wilbanks GD, Kuroda M, Maemura T, Huang M, Zheng NY, Turner HL, Erickson SA, Fu Y, et al. Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody to antigenically distinct Omicron subvariants. The Journal of Clinical Investigation. PMID 36862518 DOI: 10.1172/JCI166844 |
0.315 |
|
| 2022 |
van Schooten J, Schorcht A, Farokhi E, Umotoy JC, Gao H, van den Kerkhof TLGM, Dorning J, Rijkhold Meesters TG, van der Woude P, Burger JA, Bijl T, Ghalaiyini R, Torrents de la Peña A, Turner HL, Labranche CC, ... ... Ozorowski G, et al. Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer. Plos Pathogens. 18: e1010945. PMID 36395347 DOI: 10.1371/journal.ppat.1010945 |
0.413 |
|
| 2022 |
Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torre JL, Lee WH, Georgeson E, Kubitz M, Hodges S, et al. Long-primed germinal centres with enduring affinity maturation and clonal migration. Nature. PMID 36131022 DOI: 10.1038/s41586-022-05216-9 |
0.313 |
|
| 2022 |
Zhao F, Berndsen ZT, Pedreño-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, et al. Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nature Communications. 13: 5236. PMID 36068229 DOI: 10.1038/s41467-022-32783-2 |
0.359 |
|
| 2022 |
Tas JMJ, Koo JH, Lin YC, Xie Z, Steichen JM, Jackson AM, Hauser BM, Wang X, Cottrell CA, Torres JL, Warner JE, Kirsch KH, Weldon SR, Groschel B, Nogal B, ... Ozorowski G, et al. Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses. Immunity. PMID 35987201 DOI: 10.1016/j.immuni.2022.07.020 |
0.319 |
|
| 2022 |
Zhao F, Keating C, Ozorowski G, Shaabani N, Francino-Urdaniz IM, Barman S, Limbo O, Burns A, Zhou P, Ricciardi MJ, Woehl J, Tran Q, Turner HL, Peng L, Huang D, et al. TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience. 104914. PMID 35971553 DOI: 10.1016/j.isci.2022.104914 |
0.327 |
|
| 2022 |
van Schooten J, Farokhi E, Schorcht A, van den Kerkhof TLGM, Gao H, van der Woude P, Burger JA, Meesters TGR, Bijl T, Ghalaiyini R, Turner HL, Dorning J, van Schaik BDC, van Kampen AHC, Labranche CC, ... ... Ozorowski G, et al. Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nature Communications. 13: 4515. PMID 35922441 DOI: 10.1038/s41467-022-32208-0 |
0.417 |
|
| 2022 |
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, et al. Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120976119. PMID 35549549 DOI: 10.1073/pnas.2120976119 |
0.33 |
|
| 2022 |
Hurlburt NK, Homad LJ, Sinha I, Jennewein MF, MacCamy AJ, Wan YH, Boonyaratanakornkit J, Sholukh AM, Jackson AM, Zhou P, Burton DR, Andrabi R, Ozorowski G, Ward AB, Stamatatos L, et al. Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit. Communications Biology. 5: 342. PMID 35411021 DOI: 10.1038/s42003-022-03262-7 |
0.353 |
|
| 2022 |
Sahoo A, Hodge EA, LaBranche CC, Styles TM, Shen X, Cheedarla N, Shiferaw A, Ozorowski G, Lee WH, Ward AB, Tomaras GD, Montefiori DC, Irvine DJ, Lee KK, Amara RR. Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies. Cell Reports. 38: 110436. PMID 35235790 DOI: 10.1016/j.celrep.2022.110436 |
0.359 |
|
| 2021 |
Schorcht A, Cottrell CA, Pugach P, Ringe RP, Han AX, Allen JD, van den Kerkhof TLGM, Seabright GE, Schermer EE, Ketas TJ, Burger JA, van Schooten J, LaBranche CC, Ozorowski G, de Val N, et al. The glycan hole area of HIV-1 envelope trimers contributes prominently to the induction of autologous neutralization. Journal of Virology. JVI0155221. PMID 34669426 DOI: 10.1128/JVI.01552-21 |
0.359 |
|
| 2021 |
Jennewein MF, MacCamy AJ, Akins NR, Feng J, Homad LJ, Hurlburt NK, Seydoux E, Wan YH, Stuart AB, Edara VV, Floyd K, Vanderheiden A, Mascola JR, Doria-Rose N, Wang L, ... ... Ozorowski G, et al. Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects. Cell Reports. 109353. PMID 34237283 DOI: 10.1016/j.celrep.2021.109353 |
0.314 |
|
| 2021 |
Kumar S, Lin X, Ngo T, Shapero B, Sou C, Allen JD, Copps J, Zhang L, Ozorowski G, He L, Crispin M, Ward AB, Wilson IA, Zhu J. Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles. Mbio. e0042921. PMID 34156262 DOI: 10.1128/mBio.00429-21 |
0.354 |
|
| 2021 |
Kumar R, Deshpande S, Sewall LM, Ozorowski G, Cottrell CA, Lee WH, Holden LG, Richey ST, Chandrawacar AS, Dhiman K, Ashish F, Kumar V, Ahmed S, Hingankar N, Kumar N, et al. Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer. Plos Pathogens. 17: e1008977. PMID 33826683 DOI: 10.1371/journal.ppat.1008977 |
0.36 |
|
| 2020 |
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB. A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Reports. 33: 108428. PMID 33238117 DOI: 10.1016/j.celrep.2020.108428 |
0.317 |
|
| 2020 |
Schorcht A, van den Kerkhof TLGM, Cottrell CA, Allen JD, Torres JL, Behrens AJ, Schermer EE, Burger JA, de Taeye SW, de la Peña AT, Bontjer I, Gumbs S, Ozorowski G, LaBranche CC, de Val N, et al. Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers. Journal of Virology. PMID 32999024 DOI: 10.1128/JVI.01214-20 |
0.404 |
|
| 2020 |
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, et al. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathogens. 16: e1008753. PMID 32866207 DOI: 10.1371/Journal.Ppat.1008753 |
0.478 |
|
| 2020 |
Carnathan DG, Kaushik K, Ellebedy AH, Enemuo CA, Gebru EH, Dhadvai P, Rasheed MAU, Pauthner MG, Ozorowski G, Ahmed R, Burton DR, Ward AB, Silvestri G, Crotty S, Locci M. Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers. Frontiers in Immunology. 11: 1213. PMID 32612608 DOI: 10.3389/Fimmu.2020.01213 |
0.392 |
|
| 2020 |
Nogal B, McCoy LE, van Gils MJ, Cottrell CA, Voss JE, Andrabi R, Pauthner M, Liang CH, Messmer T, Nedellec R, Shin M, Turner HL, Ozorowski G, Sanders RW, Burton DR, et al. HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite. Science Advances. 6: eaba0512. PMID 32548265 DOI: 10.1126/Sciadv.Aba0512 |
0.469 |
|
| 2020 |
Klasse PJ, Ozorowski G, Sanders RW, Moore JP. Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens? Cell Host & Microbe. 27: 507-518. PMID 32272076 DOI: 10.1016/J.Chom.2020.03.018 |
0.505 |
|
| 2020 |
Yang YR, McCoy LE, van Gils MJ, Andrabi R, Turner HL, Yuan M, Cottrell CA, Ozorowski G, Voss J, Pauthner M, Polveroni TM, Messmer T, Wilson IA, Sanders RW, Burton DR, et al. Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits. Journal of Virology. PMID 31941772 DOI: 10.1128/Jvi.01861-19 |
0.42 |
|
| 2020 |
Yang YR, McCoy LE, Gils MJv, Andrabi R, Turner HL, Yuan M, Cottrell CA, Ozorowski G, Voss J, Pauthner M, Polveroni TM, Messmer T, Wilson IA, Sanders RW, Burton DR, et al. Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits. Journal of Virology. DOI: 10.2210/Pdb6U59/Pdb |
0.436 |
|
| 2019 |
Ringe RP, Cruz Portillo VM, Dosenovic P, Ketas TJ, Ozorowski G, Nogal B, Perez L, LaBranche CC, Lim J, Francomano E, Wilson IA, Sanders RW, Ward AB, Montefiori DC, Nussenzweig MC, et al. Neutralizing antibody induction by HIV-1 Envelope glycoprotein SOSIP trimers on iron oxide nanoparticles may be impaired by mannose binding lectin. Journal of Virology. PMID 31852794 DOI: 10.1128/Jvi.01883-19 |
0.392 |
|
| 2019 |
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vázquez Bernat N, et al. Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity. PMID 31732167 DOI: 10.1016/J.Immuni.2019.10.008 |
0.501 |
|
| 2019 |
Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.). PMID 31672916 DOI: 10.1126/Science.Aax4380 |
0.48 |
|
| 2019 |
Yuan M, Cottrell CA, Ozorowski G, van Gils MJ, Kumar S, Wu NC, Sarkar A, Torres JL, de Val N, Copps J, Moore JP, Sanders RW, Ward AB, Wilson IA. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host & Microbe. 25: 873-883.e5. PMID 31194940 DOI: 10.1016/J.Chom.2019.04.011 |
0.504 |
|
| 2019 |
Sliepen K, Han BW, Bontjer I, Mooij P, Garces F, Behrens AJ, Rantalainen K, Kumar S, Sarkar A, Brouwer PJM, Hua Y, Tolazzi M, Schermer E, Torres JL, Ozorowski G, et al. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nature Communications. 10: 2355. PMID 31142746 DOI: 10.1038/S41467-019-10262-5 |
0.487 |
|
| 2019 |
Meuser ME, Rashad AA, Ozorowski G, Dick A, Ward AB, Cocklin S. Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor. Molecules (Basel, Switzerland). 24. PMID 31013646 DOI: 10.3390/Molecules24081581 |
0.38 |
|
| 2019 |
Lei L, Yang YR, Tran K, Wang Y, Chiang CI, Ozorowski G, Xiao Y, Ward AB, Wyatt RT, Li Y. The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization. Cell Reports. 27: 586-598.e6. PMID 30970260 DOI: 10.1016/J.Celrep.2019.03.039 |
0.439 |
|
| 2019 |
Whitaker N, Hickey JM, Kaur K, Xiong J, Sawant N, Cupo A, Lee WH, Ozorowski G, Medina-Ramírez M, Ward AB, Sanders RW, Moore JP, Joshi SB, Volkin DB, Dey AK. Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 envelope glycoprotein trimers as candidate vaccine antigens. Journal of Pharmaceutical Sciences. PMID 30776383 DOI: 10.1016/J.Xphs.2019.01.033 |
0.433 |
|
| 2019 |
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell C, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman D, Bernat NV, Turner H, et al. Vaccine-elicited cross-neutralizing HIV antibodies directed to multiple sites of Env vulnerability following heterologous NFL trimer-liposome prime:boosting Immunity. DOI: 10.2210/Pdb6P65/Pdb |
0.458 |
|
| 2018 |
Ringe RP, Pugach P, Cottrell CA, LaBranche CC, Seabright GE, Ketas TJ, Ozorowski G, Kumar S, Schorcht A, van Gils MJ, Crispin M, Montefiori DC, Wilson IA, Ward AB, Sanders RW, et al. Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes. Journal of Virology. PMID 30487280 DOI: 10.1128/Jvi.01656-18 |
0.508 |
|
| 2018 |
He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, et al. HIV-1 vaccine design through minimizing envelope metastability. Science Advances. 4: eaau6769. PMID 30474059 DOI: 10.1126/Sciadv.Aau6769 |
0.438 |
|
| 2018 |
Aldon Y, McKay PF, Allen J, Ozorowski G, Felfödiné Lévai R, Tolazzi M, Rogers P, He L, de Val N, Fábián K, Scarlatti G, Zhu J, Ward AB, Crispin M, Shattock RJ. Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers. Cell Reports. 24: 3324-3338.e5. PMID 30232012 DOI: 10.1016/J.Celrep.2018.08.051 |
0.505 |
|
| 2018 |
Ozorowski G, Cupo A, Golabek M, LoPiccolo M, Ketas TA, Cavallary M, Cottrell CA, Klasse PJ, Ward AB, Moore JP. Effects of adjuvants on HIV-1 envelope glycoprotein SOSIP trimers . Journal of Virology. PMID 29669838 DOI: 10.1128/Jvi.00381-18 |
0.496 |
|
| 2018 |
Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, LaBranche CC, van Gils MJ, Bricault CA, Barouch DH, Crotty S, Silvestri G, et al. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. Plos Pathogens. 14: e1006913. PMID 29474444 DOI: 10.1371/Journal.Ppat.1006913 |
0.492 |
|
| 2018 |
Shrivastava T, Samal S, Tyagi AK, Goswami S, Kumar N, Ozorowski G, Ward AB, Chakrabarti BK. Envelope proteins of two HIV-1 clades induced different epitope-specific antibody response. Vaccine. PMID 29429810 DOI: 10.1016/J.Vaccine.2018.01.081 |
0.495 |
|
| 2018 |
Behrens AJ, Kumar A, Medina-Ramirez M, Cupo A, Marshall K, Cruz Portillo VM, Harvey DJ, Ozorowski G, Zitzmann N, Wilson IA, Ward AB, Struwe WB, Moore JP, Sanders RW, Crispin M. Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages. Journal of Proteome Research. PMID 29420040 DOI: 10.1021/Acs.Jproteome.7B00639 |
0.43 |
|
| 2017 |
Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhniy O, Willis JR, Kubitz M, Adachi Y, Reiss SM, et al. Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding. Nature Communications. 8: 1655. PMID 29162799 DOI: 10.1038/S41467-017-01549-6 |
0.493 |
|
| 2017 |
Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens AJ, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E, Desaire H, Crispin M, Wilson IA, Sanders RW, Hassell T, et al. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate. Biotechnology and Bioengineering. PMID 29150937 DOI: 10.1002/Bit.26498 |
0.434 |
|
| 2017 |
He L, Lin X, de Val N, Saye-Francisco KL, Mann CJ, Augst R, Morris CD, Azadnia P, Zhou B, Sok D, Ozorowski G, Ward AB, Burton DR, Zhu J. Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer. Frontiers in Immunology. 8: 1025. PMID 28883821 DOI: 10.3389/Fimmu.2017.01025 |
0.504 |
|
| 2017 |
Sullivan JT, Sulli C, Nilo A, Yasmeen A, Ozorowski G, Sanders RW, Ward AB, Klasse PJ, Moore JP, Doranz BJ. High-throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers. Journal of Virology. PMID 28878072 DOI: 10.1128/Jvi.00862-17 |
0.501 |
|
| 2017 |
Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens AJ, Ozorowski G, van den Kerkhof TLGM, Freund NT, Dosenovic P, Hua Y, Gitlin AD, et al. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of Experimental Medicine. PMID 28847869 DOI: 10.1084/Jem.20161160 |
0.516 |
|
| 2017 |
Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, et al. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Reports. 20: 1805-1817. PMID 28834745 DOI: 10.1016/J.Celrep.2017.07.077 |
0.496 |
|
| 2017 |
Kumar R, Ozorowski G, Kumar V, Holden LG, Shrivastava T, Patil S, Deshpande S, Ward AB, Bhattacharya J. Characterization of a stable HIV-1 B/C recombinant, soluble and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes. The Journal of Biological Chemistry. PMID 28743743 DOI: 10.1074/Jbc.M117.803056 |
0.477 |
|
| 2017 |
Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB. Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature. PMID 28700571 DOI: 10.1038/Nature23010 |
0.486 |
|
| 2017 |
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Ozorowski G, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007 |
0.416 |
|
| 2017 |
Ringe RP, Ozorowski G, Rantalainen K, Struwe WB, Matthews K, Torres JL, Yasmeen A, Cottrell CA, Ketas TJ, LaBranche CC, Montefiori DC, Cupo A, Crispin M, Wilson IA, Ward AB, et al. Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers. Journal of Virology. PMID 28539451 DOI: 10.1128/Jvi.00677-17 |
0.485 |
|
| 2017 |
Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, et al. Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 46: 777-791.e10. PMID 28514685 DOI: 10.1016/J.Immuni.2017.04.011 |
0.524 |
|
| 2017 |
Hopper JTS, Ambrose S, Grant OC, Krumm SA, Allison TM, Degiacomi MT, Tully MD, Pritchard LK, Ozorowski G, Ward AB, Crispin M, Doores KJ, Woods RJ, Benesch JLP, Robinson CV, et al. The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans. Structure (London, England : 1993). PMID 28434916 DOI: 10.1016/J.Str.2017.03.015 |
0.464 |
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| 2017 |
Ringe RP, Ozorowski G, Yasmeen A, Cupo A, Cruz Portillo VM, Pugach P, Golabek M, Rantalainen K, Holden LG, Cottrell CA, Wilson IA, Sanders RW, Ward AB, Klasse PJ, Moore JP. Improving the expression and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers by targeted sequence changes. Journal of Virology. PMID 28381572 DOI: 10.1128/Jvi.00264-17 |
0.493 |
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| 2017 |
Ahmed S, Shrivastava T, Kumar N, Ozorowski G, Ward AB, Chakrabarti BK. Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein. The Journal of Biological Chemistry. PMID 28283570 DOI: 10.1074/Jbc.M117.776419 |
0.486 |
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| 2017 |
Wibmer CK, Gorman J, Ozorowski G, Bhiman JN, Sheward DJ, Elliott DH, Rouelle J, Smira A, Joyce MG, Ndabambi N, Druz A, Asokan M, Burton DR, Connors M, Abdool Karim SS, et al. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. Plos Pathogens. 13: e1006074. PMID 28076415 DOI: 10.1371/Journal.Ppat.1006074 |
0.491 |
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| 2016 |
van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. PMID 27841852 DOI: 10.1038/Nmicrobiol.2016.199 |
0.509 |
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| 2016 |
Klasse PJ, LaBranche CC, Ketas TJ, Ozorowski G, Cupo A, Pugach P, Ringe RP, Golabek M, van Gils MJ, Guttman M, Lee KK, Wilson IA, Butera ST, Ward AB, Montefiori DC, et al. Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C. Plos Pathogens. 12: e1005864. PMID 27627672 DOI: 10.1371/Journal.Ppat.1005864 |
0.403 |
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| 2016 |
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016 |
0.458 |
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| 2016 |
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Ozorowski G, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005 |
0.47 |
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| 2016 |
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M, Menis S, Cottrell CA, Torres JL, Hsueh J, Schief WR, et al. Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies. Cell Reports. PMID 27545891 DOI: 10.1016/J.Celrep.2016.07.074 |
0.502 |
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| 2016 |
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, et al. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (New York, N.Y.). 352: 828-33. PMID 27174988 DOI: 10.1126/Science.Aae0474 |
0.429 |
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| 2016 |
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. PMID 27067056 DOI: 10.1016/J.Immuni.2016.03.006 |
0.396 |
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| 2016 |
Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang GY, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang KK, Iyengar S, et al. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell. PMID 26949186 DOI: 10.1016/J.Cell.2016.02.022 |
0.401 |
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| 2016 |
Lee JH, Ozorowski G, Ward AB. Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 351: 1043-8. PMID 26941313 DOI: 10.1126/Science.Aad2450 |
0.494 |
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| 2016 |
Kong L, Ju B, Ren L, Chen Y, Liu J, He L, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Deller MC, Hao Y, Feng Y, et al. Critical determinants in the emergence of broadly neutralizing CD4-binding site antibodies from an HIV-1-infected Chinese donor Immunity. DOI: 10.2210/Pdb5Cd3/Pdb |
0.427 |
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| 2016 |
Sliepen K, Ozorowski G, Burger J, Montfort Tv, Stunnenberg M, Bontjer I, LaBranche C, Montefiori D, Moore J, Ward A, Sanders R. D-102 Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity Journal of Acquired Immune Deficiency Syndromes. 71: 52. DOI: 10.1097/01.Qai.0000479550.29238.84 |
0.344 |
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| 2015 |
de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/J.Cell.2015.11.056 |
0.461 |
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| 2015 |
Sliepen K, van Montfort T, Ozorowski G, Pritchard LK, Crispin M, Ward AB, Sanders RW. Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer. Biomolecules. 5: 2919-34. PMID 26512709 DOI: 10.3390/biom5042919 |
0.375 |
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| 2015 |
Schiffner T, de Val N, Russell RA, de Taeye SW, Torrents de la Pena A, Ozorowski G, Kim HJ, Nieusma T, Brod F, Cupo A, Sanders RW, Moore JP, Ward AB, Sattentau QJ. Chemical Cross-linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens. Journal of Virology. PMID 26512083 DOI: 10.1128/Jvi.01942-15 |
0.51 |
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| 2015 |
Sliepen K, Ozorowski G, Burger JA, van Montfort T, Stunnenberg M, LaBranche C, Montefiori DC, Moore JP, Ward AB, Sanders RW. Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity. Retrovirology. 12: 82. PMID 26410741 DOI: 10.1186/S12977-015-0210-4 |
0.394 |
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| 2015 |
Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature Communications. 6: 8167. PMID 26404402 DOI: 10.1038/Ncomms9167 |
0.481 |
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| 2015 |
Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Peña A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, et al. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens. Proceedings of the National Academy of Sciences of the United States of America. PMID 26372963 DOI: 10.1073/Pnas.1507793112 |
0.517 |
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| 2015 |
Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, et al. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers. Journal of Virology. PMID 26311893 DOI: 10.1128/Jvi.01768-15 |
0.473 |
|
| 2015 |
Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I, Stanfield R, Ward AB, Burton DR, Klasse PJ, Sanders RW, et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity. Journal of Virology. PMID 26246566 DOI: 10.1128/Jvi.01653-15 |
0.484 |
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| 2015 |
Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, et al. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science (New York, N.Y.). 349: aac4223. PMID 26089353 DOI: 10.1126/Science.Aac4223 |
0.491 |
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| 2015 |
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers. Cell Reports. 11: 1604-13. PMID 26051934 DOI: 10.1016/J.Celrep.2015.05.017 |
0.516 |
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| 2015 |
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. Plos Pathogens. 11: e1004767. PMID 25807248 DOI: 10.1371/Journal.Ppat.1004767 |
0.494 |
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| 2015 |
Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. Journal of Virology. 89: 3380-95. PMID 25589637 DOI: 10.1128/Jvi.03473-14 |
0.486 |
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| 2013 |
Ran T, Ozorowski G, Gao Y, Sineshchekov OA, Wang W, Spudich JL, Luecke H. Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes. Acta Crystallographica. Section D, Biological Crystallography. 69: 1965-80. PMID 24100316 DOI: 10.1107/S0907444913017575 |
0.617 |
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| 2013 |
Ozorowski G, Milton S, Luecke H. Structure of a C-terminal AHNAK peptide in a 1:2:2 complex with S100A10 and an acetylated N-terminal peptide of annexin A2. Acta Crystallographica. Section D, Biological Crystallography. 69: 92-104. PMID 23275167 DOI: 10.1107/S0907444912043429 |
0.636 |
|
| 2012 |
Ozorowski G, Ryan CM, Whitelegge JP, Luecke H. Withaferin A binds covalently to the N-terminal domain of annexin A2. Biological Chemistry. 393: 1151-63. PMID 23091278 DOI: 10.1515/Hsz-2012-0184 |
0.621 |
|
| 2012 |
Nazmi AR, Ozorowski G, Pejic M, Whitelegge JP, Gerke V, Luecke H. N-terminal acetylation of annexin A2 is required for S100A10 binding. Biological Chemistry. 393: 1141-50. PMID 23091277 DOI: 10.1515/Hsz-2012-0179 |
0.629 |
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| 2012 |
Spudich EN, Ozorowski G, Schow EV, Tobias DJ, Spudich JL, Luecke H. A transporter converted into a sensor, a phototaxis signaling mutant of bacteriorhodopsin at 3.0 Å. Journal of Molecular Biology. 415: 455-63. PMID 22123198 DOI: 10.1016/J.Jmb.2011.11.025 |
0.598 |
|
| 2009 |
Pathuri P, Nguyen ET, Ozorowski G, Svärd SG, Luecke H. Apo and calcium-bound crystal structures of cytoskeletal protein alpha-14 giardin (annexin E1) from the intestinal protozoan parasite Giardia lamblia. Journal of Molecular Biology. 385: 1098-112. PMID 19046974 DOI: 10.1016/J.Jmb.2008.11.012 |
0.657 |
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