Robert A. Nichols - Publications

Affiliations: 
University of Hawaii, Honolulu, HI, United States 
Area:
Alzheimer's disease

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Arora K, Belcaid M, Lantz MJ, Taketa R, Nichols RA. Transcriptome Profile of Nicotinic Receptor-Linked Sensitization of Beta Amyloid Neurotoxicity. Scientific Reports. 10: 5696. PMID 32231242 DOI: 10.1038/S41598-020-62726-0  0.328
2018 Morel C, Sherrin T, Kennedy NJ, Forest KH, Avcioglu Barutcu S, Robles M, Carpenter-Hyland E, Alfulaij N, Standen CL, Nichols RA, Benveniste M, Davis RJ, Todorovic C. JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29540552 DOI: 10.1523/Jneurosci.1913-17.2018  0.306
2015 Arora K, Cheng J, Nichols RA. Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid. The Journal of Biological Chemistry. 290: 21409-20. PMID 26139609 DOI: 10.1074/Jbc.M114.634162  0.35
2014 Lawrence JL, Tong M, Alfulaij N, Sherrin T, Contarino M, White MM, Bellinger FP, Todorovic C, Nichols RA. Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal β-amyloid fragment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14210-8. PMID 25339735 DOI: 10.1523/Jneurosci.0326-14.2014  0.328
2011 Tong M, Arora K, White MM, Nichols RA. Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid. The Journal of Biological Chemistry. 286: 34373-81. PMID 21828053 DOI: 10.1074/Jbc.M111.241299  0.331
2011 Yang K, Buhlman L, Khan GM, Nichols RA, Jin G, McIntosh JM, Whiteaker P, Lukas RJ, Wu J. Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2537-48. PMID 21325521 DOI: 10.1523/Jneurosci.3003-10.2011  0.334
2010 Khan GM, Tong M, Jhun M, Arora K, Nichols RA. beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts. The European Journal of Neuroscience. 31: 788-96. PMID 20374280 DOI: 10.1111/J.1460-9568.2010.07116.X  0.385
2009 Dougherty JJ, Nichols RA. Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals. Acta Pharmacologica Sinica. 30: 788-94. PMID 19498419 DOI: 10.1038/Aps.2009.62  0.393
2009 Mehta TK, Dougherty JJ, Wu J, Choi CH, Khan GM, Nichols RA. Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants. Journal of Neurochemistry. 109: 1452-8. PMID 19457164 DOI: 10.1111/J.1471-4159.2009.06070.X  0.344
2008 Dougherty JJ, Wu J, Mehta TK, Brown B, Nichols RA. Chronic nicotine alters nicotinic receptor-induced presynaptic Ca2+ responses in isolated nerve terminals. Neurochemical Research. 33: 1106-12. PMID 18095155 DOI: 10.1007/S11064-007-9557-9  0.38
2007 Wu J, Khan GM, Nichols RA. Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors. Brain Research. 1182: 82-9. PMID 17935702 DOI: 10.1016/J.Brainres.2007.08.079  0.351
2007 Nichols RA, Dengler AF, Nakagawa EM, Bashkin M, Paul BT, Wu J, Khan GM. A constitutive, transient receptor potential-like Ca2+ influx pathway in presynaptic nerve endings independent of voltage-gated Ca2+ channels and Na+/Ca2+ exchange. The Journal of Biological Chemistry. 282: 36102-11. PMID 17928293 DOI: 10.1074/Jbc.M706002200  0.398
2006 Wu J, Dougherty JJ, Nichols RA. Dopamine receptor regulation of Ca2+ levels in individual isolated nerve terminals from rat striatum: comparison of presynaptic D1-like and D2-like receptors. Journal of Neurochemistry. 98: 481-94. PMID 16805841 DOI: 10.1111/J.1471-4159.2006.03901.X  0.362
2006 Nichols RA, Choi CH, Wu J, Mehta TK, Bates B, Dougherty JJ. P3-436: Beta amyloid regulation of presynaptic calcium in mouse cortex via alpha7-beta2 subtype nicotinic receptors Alzheimer's & Dementia. 2: S504-S504. DOI: 10.1016/J.Jalz.2006.05.1707  0.301
2003 Dougherty JJ, Wu J, Nichols RA. Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6740-7. PMID 12890766  0.305
2003 Dougherty JJ, Wu J, Nichols RA. β-Amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex The Journal of Neuroscience. 23: 6740-6747. DOI: 10.1523/Jneurosci.23-17-06740.2003  0.411
2002 van Hooft JA, Dougherty JJ, Endeman D, Nichols RA, Wadman WJ. Gabapentin inhibits presynaptic Ca(2+) influx and synaptic transmission in rat hippocampus and neocortex. European Journal of Pharmacology. 449: 221-28. PMID 12167463 DOI: 10.1016/S0014-2999(02)02044-7  0.398
2001 Nayak SV, Dougherty JJ, McIntosh JM, Nichols RA. Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals. Journal of Neurochemistry. 76: 1860-70. PMID 11259504 DOI: 10.1046/J.1471-4159.2001.00197.X  0.424
2001 Rondé P, Nichols RA. Postsynaptic target regulates functional responses induced by 5-HT3 serotonin receptors on axonal varicosities of NG108-15 hybrid neuroblastoma cells. Neuroscience. 102: 979-87. PMID 11182259 DOI: 10.1016/S0306-4522(00)00512-1  0.375
2000 Rondé P, Dougherty JJ, Nichols RA. Functional IP3- and ryanodine-sensitive calcium stores in presynaptic varicosities of NG108-15 (rodent neuroblastoma x glioma hybrid) cells. The Journal of Physiology. 529: 307-19. PMID 11101642 DOI: 10.1111/J.1469-7793.2000.00307.X  0.397
2000 Nayak SV, Rondé P, Spier AD, Lummis SC, Nichols RA. Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals. Neuropharmacology. 39: 2681-90. PMID 11044738 DOI: 10.1016/S0028-3908(00)00109-X  0.374
1999 Nayak SV, Rondé P, Spier AD, Lummis SC, Nichols RA. Calcium changes induced by presynaptic 5-hydroxytryptamine-3 serotonin receptors on isolated terminals from various regions of the rat brain. Neuroscience. 91: 107-17. PMID 10336063 DOI: 10.1016/S0306-4522(98)00520-X  0.44
1998 Hou WF, Zhang SP, Davidkova G, Nichols RA, Weiss B. Effect of antisense oligodeoxynucleotides directed to individual calmodulin gene transcripts on the proliferation and differentiation of PC12 cells. Antisense & Nucleic Acid Drug Development. 8: 295-308. PMID 9743467 DOI: 10.1089/Oli.1.1998.8.295  0.302
1998 Rondé P, Nichols RA. High calcium permeability of serotonin 5-HT3 receptors on presynaptic nerve terminals from rat striatum. Journal of Neurochemistry. 70: 1094-103. PMID 9489730 DOI: 10.1046/J.1471-4159.1998.70031094.X  0.393
1997 Rondé P, Nichols RA. 5-HT3 receptors induce rises in cytosolic and nuclear calcium in NG108-15 cells via calcium-induced calcium release. Cell Calcium. 22: 357-65. PMID 9448942 DOI: 10.1016/S0143-4160(97)90020-8  0.41
1996 Davidkova G, Zhang SP, Nichols RA, Weiss B. Reduced level of calmodulin in PC12 cells induced by stable expression of calmodulin antisense RNA inhibits cell proliferation and induces neurite outgrowth. Neuroscience. 75: 1003-19. PMID 8938737 DOI: 10.1016/0306-4522(96)00230-8  0.352
1996 Nichols RA, Suplick GR. Rapid chelation of calcium entering isolated rat brain nerve terminals during stimulation inhibits neurotransmitter release. Neuroscience Letters. 211: 135-7. PMID 8830863 DOI: 10.1016/0304-3940(96)12728-2  0.442
1996 Nichols RA, Mollard P. Direct observation of serotonin 5-HT3 receptor-induced increases in calcium levels in individual brain nerve terminals. Journal of Neurochemistry. 67: 581-92. PMID 8764583 DOI: 10.1046/J.1471-4159.1996.67020581.X  0.437
1995 Natsukari N, Zhang SP, Nichols RA, Weiss B. Immunocytochemical localization of calmodulin in PC12 cells and its possible interaction with histones. Neurochemistry International. 26: 465-76. PMID 7492944 DOI: 10.1016/0197-0186(94)00156-O  0.341
1994 Nichols RA, Suplick GR, Brown JM. Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate. The Journal of Biological Chemistry. 269: 23817-23. PMID 7522234  0.397
1993 Sihra TS, Nichols RA. Mechanisms in the regulation of neurotransmitter release from brain nerve terminals: current hypotheses. Neurochemical Research. 18: 47-58. PMID 8096629 DOI: 10.1007/Bf00966922  0.634
1993 Sihra TS, Piomelli D, Nichols RA. Barium evokes glutamate release from rat brain synaptosomes by membrane depolarization: involvement of K+, Na+, and Ca2+ channels. Journal of Neurochemistry. 61: 1220-30. PMID 7690845 DOI: 10.1111/J.1471-4159.1993.Tb13612.X  0.676
1992 Nichols RA, Chilcote TJ, Czernik AJ, Greengard P. Synapsin I regulates glutamate release from rat brain synaptosomes. Journal of Neurochemistry. 58: 783-5. PMID 1345942 DOI: 10.1111/J.1471-4159.1992.Tb09788.X  0.553
1992 Bai G, Nichols RA, Weiss B. Cyclic AMP selectively up-regulates calmodulin genes I and II in PC12 cells. Biochimica Et Biophysica Acta. 1130: 189-96. PMID 1314092 DOI: 10.1016/0167-4781(92)90527-7  0.308
1991 Han HQ, Nichols RA, Rubin MR, Bähler M, Greengard P. Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb. Nature. 349: 697-700. PMID 1899916 DOI: 10.1038/349697A0  0.467
1990 Nichols RA, Sihra TS, Czernik AJ, Nairn AC, Greengard P. Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes. Nature. 343: 647-51. PMID 2154695 DOI: 10.1038/343647A0  0.712
1989 Nichols RA, Chandler CE, Shooter EM. Enucleation of the rat pheochromocytoma clonal cell line, PC12: effect on neurite outgrowth. Journal of Cellular Physiology. 141: 301-9. PMID 2808539 DOI: 10.1002/jcp.1041410211  0.462
1989 Nichols RA, Wu WC, Haycock JW, Greengard P. Introduction of impermeant molecules into synaptosomes using freeze/thaw permeabilization. Journal of Neurochemistry. 52: 521-9. PMID 2536075 DOI: 10.1111/J.1471-4159.1989.Tb09151.X  0.624
1987 Isackson PJ, Silverman RE, Blaber M, Server AC, Nichols RA, Shooter EM, Bradshaw RA. Epidermal growth factor binding protein: identification of a different protein. Biochemistry. 26: 2082-5. PMID 3304419 DOI: 10.1021/Bi00382A003  0.451
1987 Romano C, Nichols RA, Greengard P, Greene LA. Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1294-9. PMID 3106589 DOI: 10.1523/Jneurosci.07-05-01294.1987  0.327
1987 Nichols RA, Haycock JW, Wang JK, Greengard P. Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes. Journal of Neurochemistry. 48: 615-21. PMID 3098922 DOI: 10.1111/J.1471-4159.1987.Tb04137.X  0.661
1987 Romano C, Nichols RA, Greengard P. Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1300-6. PMID 3033168 DOI: 10.1523/Jneurosci.07-05-01300.1987  0.323
1987 Nairn AC, Nichols RA, Brady MJ, Palfrey HC. Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells. The Journal of Biological Chemistry. 262: 14265-72. PMID 2443502  0.498
1985 Nichols RA, Shooter EM. Subunit interactions of the nerve and epidermal growth factor complexes: protection of the biological subunit from proteolytic modification. Developmental Neuroscience. 7: 216-29. PMID 3913581 DOI: 10.1159/000112290  0.546
1983 Nichols RA, Shooter EM. Characterization of the differential interaction of the microheterogeneous forms of the gamma subunit of 7 S nerve growth factor with natural and synthetic ligands. The Journal of Biological Chemistry. 258: 10296-303. PMID 6885782  0.459
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