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Maho Niwa - Publications

Affiliations: 
Biology University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Molecular Biology, Biochemistry
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Piña F, Yan B, Hu J, Niwa M. Reticulons bind sphingolipids to activate the endoplasmic reticulum cell cycle checkpoint, the ER surveillance pathway. Cell Reports. 42: 113403. PMID 37979174 DOI: 10.1016/j.celrep.2023.113403  0.325
2021 Chao JT, Pina F, Niwa M. Regulation of the early stages of endoplasmic reticulum inheritance during ER stress. Molecular Biology of the Cell. 32: 109-119. PMID 33448894 DOI: 10.1091/mbc.E20-08-0558  0.359
2020 Niwa M. A cell cycle checkpoint for the endoplasmic reticulum. Biochimica Et Biophysica Acta. Molecular Cell Research. 1867: 118825. PMID 32828757 DOI: 10.1016/J.Bbamcr.2020.118825  0.37
2020 Das B, Okamoto K, Rabalais J, Marchelletta RR, Barrett KE, Das S, Niwa M, Sivagnanam M. Congenital Tufting Enteropathy-Associated Mutant of Epithelial Cell Adhesion Molecule Activates the Unfolded Protein Response in a Murine Model of the Disease. Cells. 9. PMID 32290509 DOI: 10.3390/Cells9040946  0.513
2019 T C, Piña F, Onishi M, Cohen Y, Lai YS, Schuldiner M, Niwa M. Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. Developmental Cell. PMID 31564614 DOI: 10.1016/J.Devcel.2019.08.017  0.475
2018 Tam AB, Roberts LS, Chandra V, Rivera IG, Nomura DK, Forbes DJ, Niwa M. The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms. Developmental Cell. 46: 327-343.e7. PMID 30086303 DOI: 10.1016/J.Devcel.2018.04.023  0.79
2018 Piña F, Yagisawa F, Obara K, Gregerson JD, Kihara A, Niwa M. Sphingolipids activate the endoplasmic reticulum stress surveillance pathway. The Journal of Cell Biology. PMID 29317528 DOI: 10.1083/Jcb.201708068  0.47
2017 Miller M, Tam AB, Mueller JL, Rosenthal P, Beppu A, Gordillo R, McGeough MD, Vuong C, Doherty TA, Hoffman HM, Niwa M, Broide DH. Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. Journal of Immunology (Baltimore, Md. : 1950). PMID 28275141 DOI: 10.4049/Jimmunol.1601848  0.749
2016 Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response. Scientific Reports. 6: 33353. PMID 27634301 DOI: 10.1038/Srep33353  0.779
2016 Jiang D, Tam A, Alagappan M, Hay MP, Gupta A, Kozak M, Solow-Cordero DE, Lum PY, Denko N, Giaccia AJ, Le QT, Niwa M, Koong AC. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Cytotoxic to Human Multiple Myeloma. Molecular Cancer Therapeutics. PMID 27307600 DOI: 10.1158/1535-7163.Mct-15-1023  0.751
2016 Piña FJ, Fleming T, Pogliano K, Niwa M. Reticulons Regulate the ER Inheritance Block during ER Stress. Developmental Cell. PMID 27117666 DOI: 10.1016/J.Devcel.2016.03.025  0.452
2015 Piña FJ, Niwa M. The ER Stress Surveillance (ERSU) pathway regulates daughter cell ER protein aggregate inheritance. Elife. 4. PMID 26327697 DOI: 10.7554/Elife.06970  0.446
2015 Jiang D, Niwa M, Koong AC. Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases. Seminars in Cancer Biology. PMID 25986851 DOI: 10.1016/J.Semcancer.2015.04.010  0.503
2014 Tam AB, Koong AC, Niwa M. Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD. Cell Reports. 9: 850-8. PMID 25437541 DOI: 10.1016/J.Celrep.2014.09.016  0.775
2014 Miller M, Rosenthal P, Beppu A, Mueller JL, Hoffman HM, Tam AB, Doherty TA, McGeough MD, Pena CA, Suzukawa M, Niwa M, Broide DH. ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. Journal of Immunology (Baltimore, Md. : 1950). 192: 3475-87. PMID 24623133 DOI: 10.4049/Jimmunol.1303047  0.748
2012 Tam AB, Mercado EL, Hoffmann A, Niwa M. ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK. Plos One. 7: e45078. PMID 23110043 DOI: 10.1371/Journal.Pone.0045078  0.789
2012 Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proceedings of the National Academy of Sciences of the United States of America. 109: 16648-53. PMID 23011799 DOI: 10.1073/Pnas.1204151109  0.777
2012 Martín-Pérez R, Niwa M, López-Rivas A. ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2. Apoptosis : An International Journal On Programmed Cell Death. 17: 349-63. PMID 22072062 DOI: 10.1007/S10495-011-0673-2  0.482
2011 Chawla A, Chakrabarti S, Ghosh G, Niwa M. Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase. The Journal of Cell Biology. 193: 41-50. PMID 21444691 DOI: 10.1083/Jcb.201008071  0.663
2011 Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow-Cordero DE, Bouley DM, Offner F, Niwa M, Koong AC. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood. 117: 1311-4. PMID 21081713 DOI: 10.1182/Blood-2010-08-303099  0.777
2010 Babour A, Bicknell AA, Tourtellotte J, Niwa M. A surveillance pathway monitors the fitness of the endoplasmic reticulum to control its inheritance. Cell. 142: 256-69. PMID 20619447 DOI: 10.1016/J.Cell.2010.06.006  0.805
2010 Bicknell AA, Tourtellotte J, Niwa M. Late phase of the endoplasmic reticulum stress response pathway is regulated by Hog1 MAP kinase. The Journal of Biological Chemistry. 285: 17545-55. PMID 20382742 DOI: 10.1074/Jbc.M109.084681  0.798
2010 Bicknell AA, Niwa M. Regulating endoplasmic reticulum function through the unfolded protein response Handbook of Cell Signaling, 2/E. 3: 2511-2525. DOI: 10.1016/B978-0-12-374145-5.00299-0  0.796
2009 DuRose JB, Scheuner D, Kaufman RJ, Rothblum LI, Niwa M. Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress. Molecular and Cellular Biology. 29: 4295-307. PMID 19470760 DOI: 10.1128/Mcb.00260-09  0.478
2008 Brunsing R, Omori SA, Weber F, Bicknell A, Friend L, Rickert R, Niwa M. B- and T-cell development both involve activity of the unfolded protein response pathway. The Journal of Biological Chemistry. 283: 17954-61. PMID 18375386 DOI: 10.1074/Jbc.M801395200  0.772
2007 Bicknell AA, Babour A, Federovitch CM, Niwa M. A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response. The Journal of Cell Biology. 177: 1017-27. PMID 17562790 DOI: 10.1083/Jcb.200702101  0.802
2006 DuRose JB, Tam AB, Niwa M. Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress. Molecular Biology of the Cell. 17: 3095-107. PMID 16672378 DOI: 10.1091/Mbc.E06-01-0055  0.791
2006 Niwa M. The unfolded protein response unfolds Topics in Current Genetics. 16: 35-63. DOI: 10.1007/4735_115  0.395
2005 Chawla A, Niwa M. The unfolded protein response. Current Biology : Cb. 15: R907. PMID 16303544 DOI: 10.1016/J.Cub.2005.11.005  0.673
2005 Niwa M, Patil CK, DeRisi J, Walter P. Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biology. 6: R3. PMID 15642095 DOI: 10.1186/Gb-2004-6-1-R3  0.379
2001 Nock S, Gonzalez TN, Sidrauski C, Niwa M, Walter P. Purification and activity assays of the catalytic domains of the kinase/endoribonuclease Ire1p from Saccharomyces cerevisiae. Methods in Enzymology. 342: 3-10. PMID 11586903 DOI: 10.1016/S0076-6879(01)42530-4  0.451
2000 Niwa M, Walter P. Pausing to decide Proceedings of the National Academy of Sciences of the United States of America. 97: 12396-12397. PMID 11058174 DOI: 10.1073/Pnas.250476097  0.484
1999 Niwa M, Sidrauski C, Kaufman RJ, Walter P. A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell. 99: 691-702. PMID 10619423 DOI: 10.1016/S0092-8674(00)81667-0  0.357
1996 Lowell CA, Niwa M, Soriano P, Varmus HE. Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis. Blood. 87: 1780-92. PMID 8634424 DOI: 10.1182/Blood.V87.5.1780.Bloodjournal8751780  0.332
1994 Brown J, Hann B, Medzihradszky K, Niwa M, Burlingame A, Walter P. Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. The Embo Journal. 13: 4390-4400. DOI: 10.1002/J.1460-2075.1994.Tb06759.X  0.375
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