Nathan A. Bruender, Ph.D. - Publications

Affiliations: 
2012 Biochemistry-ALS University of Wisconsin, Madison, Madison, WI 
Area:
Biochemistry

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Grell TAJ, Bell BN, Nguyen C, Dowling DP, Bruender NA, Bandarian V, Drennan CL. Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity. Protein Science : a Publication of the Protein Society. PMID 30341796 DOI: 10.2210/Pdb6Nhl/Pdb  0.554
2018 Grell TAJ, Kincannon WM, Bruender NA, Blaesi EJ, Krebs C, Bandarian V, Drennan CL. Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase. The Journal of Biological Chemistry. PMID 30217813 DOI: 10.1074/Jbc.Ra118.005369  0.569
2018 Lewis JK, Bruender NA, Bandarian V. QueE: A Radical SAM Enzyme Involved in the Biosynthesis of 7-Deazapurine Containing Natural Products. Methods in Enzymology. 606: 95-118. PMID 30097106 DOI: 10.1016/Bs.Mie.2018.05.001  0.51
2018 Kincannon W, Bruender NA, Bandarian V. A Radical Clock Probe Uncouples H-atom Abstraction from Thi-oether Crosslink Formation by the Radical SAM Enzyme SkfB. Biochemistry. PMID 29965747 DOI: 10.1021/Acs.Biochem.8B00537  0.471
2018 Wilcoxen J, Bruender NA, Bandarian V, Britt RD. A Radical Intermediate in Bacillus subtilis QueE During Turnover With the Substrate Analog 6-Carboxypterin. Journal of the American Chemical Society. PMID 29303575 DOI: 10.1021/Jacs.7B10860  0.496
2017 Bruender NA, Bandarian V. The creatininase homolog MftE from Mycobacterium smegmatis catalyzes a peptide cleavage reaction in the biosynthesis of a novel RiPP. The Journal of Biological Chemistry. PMID 28077628 DOI: 10.1074/Jbc.M116.762062  0.443
2017 Bruender NA, Grell TA, Dowling DP, McCarty RM, Drennan CL, Bandarian V. 7-Carboxy-7-deazaguanine synthase - A radical S-adenosyl-L-methionine enzyme with polar tendencies. Journal of the American Chemical Society. PMID 28045519 DOI: 10.1021/Jacs.6B11381  0.524
2016 Bruender NA, Bandarian V. SkfB abstracts a hydrogen atom from Cα on SkfA to initiate thioether crosslink formation. Biochemistry. PMID 27410522 DOI: 10.1021/Acs.Biochem.6B00598  0.44
2016 Bruender NA, Bandarian V. The radical S-adenosyl-L-methionine enzyme MftC catalyzes an oxidative decarboxylation of the C-terminus of the MftA peptide. Biochemistry. PMID 27158836 DOI: 10.1021/Acs.Biochem.6B00355  0.489
2016 Bruender NA, Wilcoxen J, Britt RD, Bandarian V. Biochemical and spectroscopic characterization of a radical SAM enzyme involved in the formation of a peptide thioether crosslink. Biochemistry. PMID 27007615 DOI: 10.1021/Acs.Biochem.6B00145  0.448
2016 Bruender NA, Young AP, Bandarian V. Correction to Chemical and Biological Reduction of the Radical SAM Enzyme 7-Carboxy-7-deazaguanine Synthase. Biochemistry. PMID 26950390 DOI: 10.1021/Acs.Biochem.6B00147  0.462
2015 Bruender NA, Young AP, Bandarian V. Chemical and Biological Reduction of the Radical SAM Enzyme CPH4 Synthase. Biochemistry. 54: 2903-10. PMID 25933252 DOI: 10.1021/Acs.Biochem.5B00210  0.503
2014 Dowling DP, Bruender NA, Young AP, McCarty RM, Bandarian V, Drennan CL. Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism. Nature Chemical Biology. 10: 106-12. PMID 24362703 DOI: 10.1038/Nchembio.1426  0.526
2013 Thoden JB, Branch MC, Zimmer AL, Bruender NA, Holden HM. Active site architecture of a sugar N-oxygenase. Biochemistry. 52: 3191-3. PMID 23621882 DOI: 10.1021/Bi400407X  0.548
2012 Bruender NA, Holden HM. Probing the catalytic mechanism of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose. Protein Science : a Publication of the Protein Society. 21: 876-86. PMID 22495991 DOI: 10.1002/Pro.2074  0.62
2010 Bruender NA, Thoden JB, Kaur M, Avey MK, Holden HM. Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose. Biochemistry. 49: 5891-8. PMID 20527922 DOI: 10.1021/Bi100782B  0.592
2010 Bruender NA, Thoden JB, Holden HM. X-ray structure of kijd3, a key enzyme involved in the biosynthesis of D-kijanose. Biochemistry. 49: 3517-24. PMID 20334431 DOI: 10.1021/Bi100318V  0.62
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