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Houtan Noushmehr, Ph.D. - Publications

Affiliations: 
2011 Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
Bioinformatics Biology, Genetics, Medicine and Surgery
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99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed WR, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, ... ... Noushmehr H, et al. The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen. Cancer Research. PMID 38117484 DOI: 10.1158/0008-5472.CAN-23-2093  0.395
2023 Gielniewski B, Poleszak K, Roura AJ, Szadkowska P, Jacek K, Krol SK, Guzik R, Wiechecka P, Maleszewska M, Kaza B, Marchel A, Czernicki T, Koziarski A, Zielinski G, Styk A, ... ... Noushmehr H, et al. Targeted sequencing of cancer-related genes reveals a recurrent TOP2A variant which affects DNA binding and coincides with global transcriptional changes in glioblastoma. International Journal of Cancer. PMID 37338006 DOI: 10.1002/ijc.34631  0.331
2022 Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, ... ... Noushmehr H, et al. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. PMID 35649412 DOI: 10.1016/j.cell.2022.04.038  0.31
2022 Herrgott GA, Asmaro KP, Wells M, Sabedot TS, Malta TM, Mosella MS, Nelson K, Scarpace L, Barnholtz-Sloan JS, Sloan AE, Selman WR, deCarvalho AC, Poisson LM, Mukherjee A, Robin AM, ... ... Noushmehr H, et al. Detection of Tumor-specific DNA Methylation Markers in the Blood of Patients with Pituitary Neuroendocrine Tumors. Neuro-Oncology. PMID 35212383 DOI: 10.1093/neuonc/noac050  0.337
2021 Mosella MS, Sabedot TS, Silva TC, Malta TM, Segato FD, Asmaro KP, Wells M, Mukherjee A, Poisson LM, Snyder J, deCarvalho AC, Walbert T, Aho T, Steven K, Elias PC, ... ... Noushmehr H, et al. DNA Methylation-based Signatures Classify Sporadic Pituitary Tumors According to Clinicopathological Features. Neuro-Oncology. PMID 33631002 DOI: 10.1093/neuonc/noab044  0.355
2021 Sabedot T, Malta T, Snyder J, Nelson K, Wells M, deCarvalho A, Mukherjee A, Chitale D, Mosella M, Sokolov A, Asmaro K, Robin A, Rosenblum M, Mikkelsen T, Rock J, ... ... Noushmehr H, et al. A serum-based DNA methylation assay provides accurate detection of glioma. Neuro-Oncology. PMID 33560371 DOI: 10.1093/neuonc/noab023  0.318
2020 Chen J, Mitra A, Li S, Song S, Nguyen BN, Chen JS, Shin JH, Gough NR, Lin P, Obias V, He AR, Yao Z, Malta TM, Noushmehr H, Latham PS, et al. Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGF-β Signaling. Cancer Research. PMID 32127355 DOI: 10.1158/0008-5472.Can-19-3116  0.314
2020 Colaprico A, Olsen C, Bailey MH, Odom GJ, Terkelsen T, Silva TC, Olsen AV, Cantini L, Zinovyev A, Barillot E, Noushmehr H, Bertoli G, Castiglioni I, Cava C, Bontempi G, et al. Interpreting pathways to discover cancer driver genes with Moonlight. Nature Communications. 11: 69. PMID 31900418 DOI: 10.1038/S41467-019-13803-0  0.463
2020 Wells M, Asmaro KP, Sabedot TS, Mosella MS, Malta, PharmD TM, Nelson K, Snyder J, deCarvalho A, Mukherjee A, Chitale D, Robin A, Rosenblum ML, Mikkelsen T, Poisson L, ... ... Noushmehr H, et al. OR32-03 Serum Cell-Free Methylation-Based Signatures Distinguishes Pituitary Tumors According to Functional Status and from Other Neoplasia: A Liquid Biopsy Approach Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.542  0.428
2020 Wells M, Asmaro K, Rock J, Sabedot T, Mosella M, Malta T, Nelson K, Snyder J, Kalkanis S, Castro AV, Noushmehr H. Abstract A11: Serum cell-free DNA methylome-based signatures distinguish pituitary tumor from other neoplasias and by clinicopathologic features Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Liqbiop20-A11  0.41
2020 Sabedot T, Malta T, Snyder J, Nelson K, Wells M, deCarvalho A, Mukherjee A, Chitale D, Mosella M, Asmaro K, Robin A, Rosenblum M, Mikkelsen T, Rock J, Poisson L, ... ... Noushmehr H, et al. Abstract A10: Glioma cell-free DNA methylation marker for diagnosis and monitoring Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Liqbiop20-A10  0.488
2020 Lin X, Spindler TJ, Fonseca MAdS, Corona RI, Seo J, Dezem FS, Li L, Lee JM, Long HW, Sellers TA, Karlan BY, Noushmehr H, Freedman ML, Gayther SA, Lawrenson K. Abstract A30: Super-enhancer-associated long noncoding RNA UCA1 interacts directly with AMOT to inhibit Hippo signaling pathway in epithelial ovarian cancer Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-A30  0.307
2020 Sabedot TS, Malta TM, She R, Snyder J, Walbert T, Lee I, Kalkanis S, Ewing J, Castro A, Noushmehr H. Abstract 781: Methylation-based liquid biopsy of meningioma primary and recurrent samples Cancer Research. 80: 781-781. DOI: 10.1158/1538-7445.Am2020-781  0.479
2019 Lawrenson K, Fonseca MAS, Liu AY, Segato Dezem F, Lee JM, Lin X, Corona RI, Abbasi F, Vavra KC, Dinh HQ, Gill NK, Seo JH, Coetzee S, Lin YG, Pejovic T, ... ... Noushmehr H, et al. A Study of High-Grade Serous Ovarian Cancer Origins Implicates the SOX18 Transcription Factor in Tumor Development. Cell Reports. 29: 3726-3735.e4. PMID 31825847 DOI: 10.1016/J.Celrep.2019.10.122  0.409
2019 Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, ... ... Noushmehr H, et al. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. PMID 31748746 DOI: 10.1038/S41586-019-1775-1  0.377
2019 Victor RR, Malta TM, Seki T, Lita A, Dowdy T, Celiku O, Cavazos-Saldana A, Li A, Liu Y, Han S, Zhang W, Song H, Davis D, Lee S, Trepel JB, ... ... Noushmehr H, et al. Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas. Neuro-Oncology. PMID 31665443 DOI: 10.1093/Neuonc/Noz207  0.37
2019 Lin X, Spindler TJ, de Souza Fonseca MA, Corona RI, Seo JH, Dezem FS, Li L, Lee JM, Long HW, Sellers TA, Karlan BY, Noushmehr H, Freedman ML, Gayther SA, Lawrenson K. Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer. Iscience. 17: 242-255. PMID 31307004 DOI: 10.1016/J.Isci.2019.06.025  0.35
2019 Nassiri F, Mamatjan Y, Suppiah S, Badhiwala JH, Mansouri S, Karimi S, Saarela O, Poisson L, Gepfner-Tuma I, Schittenhelm J, Ng HK, Noushmehr H, Harter P, Baumgarten P, Weller M, et al. DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management. Neuro-Oncology. PMID 31158293 DOI: 10.1093/Neuonc/Noz061  0.336
2019 Gusev A, Lawrenson K, Lin X, Lyra PC, Kar S, Vavra KC, Segato F, Fonseca MAS, Lee JM, Pejovic T, Liu G, Karlan BY, Freedman ML, Noushmehr H, et al. A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants. Nature Genetics. PMID 31043753 DOI: 10.1038/S41588-019-0395-X  0.411
2019 Lawrenson K, Song F, Hazelett DJ, Kar SP, Tyrer J, Phelan CM, Corona RI, Rodríguez-Malavé NI, Seo JH, Adler E, Coetzee SG, Segato F, Fonseca MAS, Amos CI, Carney ME, ... ... Noushmehr H, et al. Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. Gynecologic Oncology. PMID 30898391 DOI: 10.1016/J.Ygyno.2019.02.023  0.366
2019 Mounir M, Lucchetta M, Silva TC, Olsen C, Bontempi G, Chen X, Noushmehr H, Colaprico A, Papaleo E. New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx. Plos Computational Biology. 15: e1006701. PMID 30835723 DOI: 10.1371/Journal.Pcbi.1006701  0.412
2019 Snyder J, Poisson LM, Noushmehr H, Castro AV, de Carvalho AC, Robin A, Mukherjee A, Lee I, Walbert T. Clinical and research applications of a brain tumor tissue bank in the age of precision medicine. Personalized Medicine. PMID 30816054 DOI: 10.2217/Pme-2018-0102  0.367
2019 Suppiah S, Nassiri F, Bi WL, Dunn IF, Hanemann CO, Horbinski CM, Hashizume R, James CD, Mawrin C, Noushmehr H, Perry A, Sahm F, Sloan A, Von Deimling A, Wen PY, et al. Molecular and translational advances in meningiomas. Neuro-Oncology. 21: i4-i17. PMID 30649490 DOI: 10.1093/Neuonc/Noy178  0.381
2019 Mosella M, Sabedot T, Malta T, Felicella M, Aho T, Poisson L, deCarvalho A, Noushmehr H, Rock J, Castro AV. OR24-5 Aberrant DNA Methylation in Regulatory Genomic Elements Are Associated with Invasive Behavior of Pituitary Macroadenomas: An Integrative Analysis of Epigenome-Wide Studies Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or24-5  0.41
2019 Sabedot TS, Cassel SH, Gao GF, Lareau CA, Cherniack A, Lazar A, Kadoch C, Noushmehr H. Abstract 907: Bioinformatic method to define epigenetically regulated enhancer elements associated with cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-907  0.35
2019 Malta TM, Snyder J, Wells M, deCarvalho A, Poisson L, Souza C, Zadeh G, Aldape K, Tirapelli D, Carlotti C, Lee Y, Kalkanis S, Walbert T, Noushmehr H. Abstract 841: Meningioma subgroups associated with functional genomic elements defined by DNA methylation Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-841  0.415
2019 Abraham BJ, Reddy J, Fonseca MA, Klein IA, Afeyan LK, Corona RI, Cejas P, Segato F, Karlan BY, Gayther SA, Freedman ML, Noushmehr H, Brown M, Matulonis UA, Lawrenson K, et al. Abstract 2615: Systematic approaches to predict oncogenic transcriptional regulatory circuitries identify important nodes in high-grade serous ovarian cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2615  0.33
2019 Davoodi-Bojd E, Malta T, Griffith B, Snyder J, Walbert T, Noushmehr H, Soltanian-Zadeh H. Abstract 1939: Non-invasive prediction of glioma tumor stemness using multimodal MRI Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1939  0.338
2019 Noushmehr H, Sabedot TS, Malta TM, Nelson KK, Snyder J, Wells M, Mosella MS, deCarvalho AC, Asmaro K, Scarpace L, Robin AM, Rosenblum ML, Mikkelsen T, Rock J, Walbert T, et al. Abstract LB-234: Pre-surgical identification of diagnostic, prognostic and predictive DNA methylation-based markers in serum (liquid biopsy) of patients harboring gliomas Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-234  0.498
2019 Wells M, Sabedot T, Malta T, Snyder J, Poisson L, Noushmehr H. Abstract 1640: Deep learning classification of neuro-oncology medical documents Cancer Research. 79: 1640-1640. DOI: 10.1158/1538-7445.Am2019-1640  0.332
2019 Lee IY, Sabedot T, Malta T, Snyder J, Wells M, DeCarvalho A, Mukherjee A, Chitale D, Asmaro KP, Robin AM, Rosenblum ML, Mikkelsen T, Rock JP, Poisson L, Walbert T, ... ... Noushmehr H, et al. Detection of Glioma and Prognostic Subtypes by Noninvasive Circulating Cell-Free DNA Methylation Markers Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_630  0.465
2019 Asmaro KP, Mosella MS, Wells M, Sabedot T, Malta T, Nelson K, Snyder J, DeCarvalho A, Mukherjee A, Chitale D, Aho T, Robin AM, Rosenblum ML, Mikkelsen T, Poisson L, ... ... Noushmehr H, et al. Candidate Regulatory Elements in Coding and Noncoding Regions are Associated With Invasive Behavior in Pituitary Tumors Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_157  0.459
2019 Sabedot TS, Malta T, Snyder J, Walbert T, Lee I, Kalkanis S, Castro A, Noushmehr H. Gene-61. Methylation-Based Liquid Biopsy Of Meningioma Primary And Recurrent Samples Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.463  0.326
2019 Berezovsky A, Nuga O, Meng Y, Poisson L, Noushmehr H, deCarvalho A. GENE-55. GENE EXPRESSION SIGNATURE ASSOCIATED WITH AGGRESSIVE GLIOBLASTOMA GROWTH IS ENRICHED IN CHROMATIN MODIFICATION AND STEMNESS TRANSCRIPTIONAL REGULATION PROGRAMS Neuro-Oncology. 21: vi109-vi109. DOI: 10.1093/Neuonc/Noz175.457  0.448
2019 Wells M, Sabedot TS, Asmaro K, Mosella M, Malta T, Nelson K, Snyder J, deCarvalho A, Mukherjee A, Bahn A, Robin A, Rosenblum M, Mikkelsen T, Poisson L, Lee I, ... ... Noushmehr H, et al. Gene-24. Dna Methylation Signatures Detected In A Serum-Based Liquid Biopsy Distinguish Functional And Invasiveness Features In Pituitary Adenomas Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.426  0.372
2019 Ng HK, Li KK, Malta TM, Shi Z, Noushmehr H. Combined epigenetic signature and gene copy number variations in IDH-mutant glioblastomas showed varied risk stratification Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz167.006  0.324
2019 Li KK, Chen H, Noushmehr H, Ng H. Path-15. Identification Of Subsets Of Idh-Mutant Glioblastomas With Distinct Epigenetic And Copy Number Alterations And Stratified Clinical Risks Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz126.283  0.316
2019 Mosella MQS, Sabedot TS, Malta TM, Rock J, Felicella M, Aho T, Noushmehr H, Castro AV. P13.15 DNA methylation abnormalities in non-promoter regulatory regions are associated with invasive behavior in pituitary tumors Neuro-Oncology. 21: iii65-iii66. DOI: 10.1093/Neuonc/Noz126.236  0.462
2019 Castro AV, Wells M, Asmaro K, Sabedot TS, Mosella MS, Malta TM, Nelson K, Snyder J, deCarvalho A, Mukherjee A, Chitale D, Robin A, Rosenblum M, Mikkelsen T, Poisson LM, ... ... Noushmehr H, et al. P01.02 Serum-derived DNA methylation markers distinguish functional and invasiveness subtypes in patients harboring pituitary tumors Neuro-Oncology. 21: iii24-iii24. DOI: 10.1093/Neuonc/Noz126.080  0.442
2019 Noushmehr H, Sabedot T, Malta T, Nelson K, Snyder J, Wells M, deCarvalho A, Mukherjee A, Chitale D, Mosella M, Asmaro K, Robin A, Rosenblum M, Mikkelsen T, Rock J, et al. OS1.5 Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markers Neuro-Oncology. 21: iii6-iii6. DOI: 10.1093/Neuonc/Noz126.018  0.465
2018 Buckley MA, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra PC, Coetzee SG, Shen HC, Yang AW, Earp MA, Yoder S, ... ... Noushmehr H, et al. Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus. Cancer Research. PMID 30487138 DOI: 10.1158/0008-5472.Can-17-3864  0.41
2018 Silva TC, Coetzee SG, Gull N, Yao L, Hazelett DJ, Noushmehr H, Lin DC, Berman BP. ELMER v.2: An R/Bioconductor package to reconstruct gene regulatory networks from DNA methylation and transcriptome profiles. Bioinformatics (Oxford, England). PMID 30364927 DOI: 10.1093/Bioinformatics/Bty902  0.407
2018 de Souza CF, Sabedot TS, Malta TM, Stetson L, Morozova O, Sokolov A, Laird PW, Wiznerowicz M, Iavarone A, Snyder J, deCarvalho A, Sanborn Z, McDonald KL, Friedman WA, Tirapelli D, ... ... Noushmehr H, et al. A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence. Cell Reports. 23: 637-651. PMID 29642018 DOI: 10.1016/J.Celrep.2018.03.107  0.627
2018 Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, ... ... Noushmehr H, et al. The Immune Landscape of Cancer. Immunity. PMID 29628290 DOI: 10.1016/J.Immuni.2018.03.023  0.406
2018 Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, ... ... Noushmehr H, et al. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 173: 338-354.e15. PMID 29625051 DOI: 10.1016/J.Cell.2018.03.034  0.586
2018 Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, ... ... Noushmehr H, et al. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 173: 291-304.e6. PMID 29625048 DOI: 10.1016/J.Cell.2018.03.022  0.726
2018 Aldape K, Amin SB, Ashley DM, Barnholtz-Sloan JS, Bates AJ, Beroukhim R, Bock C, Brat DJ, Claus EB, Costello JF, de Groot JF, Finocchiaro G, French PJ, Gan HK, Griffith B, ... ... Noushmehr H, et al. Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium. Neuro-Oncology. PMID 29432615 DOI: 10.1093/Neuonc/Noy020  0.396
2018 Mall R, Cerulo L, Garofano L, Frattini V, Kunji K, Bensmail H, Sabedot TS, Noushmehr H, Lasorella A, Iavarone A, Ceccarelli M. RGBM: regularized gradient boosting machines for identification of the transcriptional regulators of discrete glioma subtypes. Nucleic Acids Research. PMID 29361062 DOI: 10.1093/Nar/Gky015  0.332
2018 Snyder J, Malta TM, Noushmehr H. IDO1 expression in glioma molecular subtypes. Journal of Clinical Oncology. 36: e14029-e14029. DOI: 10.1200/Jco.2018.36.15_Suppl.E14029  0.354
2018 Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein J, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, ... ... Noushmehr H, et al. Abstract LB-373: Comprehensive analysis of cancer stemness Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-373  0.609
2018 Liu AY, Vavra KC, Corona RI, Abassi F, Fonseca M, Segato F, Freedman ML, Gayther SA, Noushmehr H, Lawrenson K. Abstract 1494: SOX18: A novel master regulator of high-grade serous ovarian tumorigenesis Cancer Research. 78: 1494-1494. DOI: 10.1158/1538-7445.Am2018-1494  0.486
2018 Sabedot T, deCarvalho A, Poisson L, Snyder J, Walbert T, Lee I, Kalkanis S, Berman B, Noushmehr H. GENE-13. GENOMIC FUNCTIONAL ENHANCERS DEFINE POTENTIAL TUMORIGENESIS OF G-CIMP-LOW (IDH-MUTANT ASTROCYTOMA) TUMORS INDEPENDENT OF PROMOTER METHYLATION Neuro-Oncology. 20: vi105-vi105. DOI: 10.1093/Neuonc/Noy148.439  0.462
2018 Malta T, Snyder J, deCarvalho A, Poisson L, Souza C, Zadeh G, Aldape K, Tirapelli D, Carlotti C, Lee I, Kalkanis S, Walbert T, Noushmehr H. GENE-09. FUNCTIONAL GENOMIC ELEMENTS DEFINED BY DNA METHYLATION CAN DISTINGUISH MENINGIOMA SUBGROUPS Neuro-Oncology. 20: vi104-vi104. DOI: 10.1093/Neuonc/Noy148.436  0.427
2018 Mosella M, Malta T, Sabedot T, Felicella M, Aho T, Poisson L, deCarvalho A, Snyder J, Lee I, Kalkanis S, Walbert T, Noushmehr H, Rock J, Castro AV. GENE-07. GENOMIC ENHANCER METHYLATION IS ASSOCIATED WITH BIOLOGICAL AND CLINICAL FEATURES IN PITUITARY TUMORS Neuro-Oncology. 20: vi104-vi104. DOI: 10.1093/Neuonc/Noy148.434  0.458
2018 Larion M, Rodado VR, Seki T, Malta T, Lita A, Dowdy T, Celiku O, Saldana AC, Li A, Zhang W, Song H, Davis D, Lee S, Neckers J, Munasinghe J, ... Noushmehr H, et al. CBMT-42. LOSS OF PROMOTER METHYLATION IN GLYCOLYTIC GENES IS ASSOCIATED WITH AGGRESSIVENESS IN IDH1-MUTANT LOWER GRADE GLIOMAS Neuro-Oncology. 20: vi41-vi42. DOI: 10.1093/Neuonc/Noy148.161  0.401
2018 Irtenkauf S, Hasselbach L, Transou A, Poisson L, Noushmehr H, Rybkin I, deCarvalho A. TMOD-06. HIGH INCIDENCE OF TUMORS AFTER TREATMENT WITH A DNA-ALKYLATING AGENT IN MOUSE STRAINS COMMONLY USED IN PRE-CLINICAL STUDIES Neuro-Oncology. 20: vi269-vi269. DOI: 10.1093/Neuonc/Noy148.1119  0.35
2017 Meliso FM, Micali D, Silva CT, Sabedot TS, Coetzee SG, Koch A, Fahlbusch FB, Noushmehr H, Schneider-Stock R, Jasiulionis MG. SIRT1 regulates Mxd1 during malignant melanoma progression. Oncotarget. 8: 114540-114553. PMID 29383100 DOI: 10.18632/Oncotarget.21457  0.388
2017 Malta TM, de Souza CF, Sabedot TS, Silva TC, Mosella MQS, Kalkanis SN, Snyder J, Castro AVB, Noushmehr H. Glioma CpG Island Methylator Phenotype (G-CIMP): Biological and Clinical Implications. Neuro-Oncology. PMID 29036500 DOI: 10.1093/Neuonc/Nox183  0.429
2017 Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, et al. Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28916733 DOI: 10.1073/Pnas.1708914114  0.392
2017 Malta T, Sokolov A, Gentles AJ, Burzykowski T, Gevaert O, Laird PW, Noushmehr H, Wiznerowicz M. Abstract LB-004: Molecular hallmarks of cancer: Stemness Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-004  0.532
2017 Mosella M, Sarraf T, Malta T, Chedraoui T, Noushmehr H, Castro AV. GENE-52. EPIGENOMIC GLIOMA SUBTYPE EVALUATION ACROSS 31 TUMOR TYPES Neuro-Oncology. 19: vi103-vi104. DOI: 10.1093/Neuonc/Nox168.424  0.384
2017 Souza C, Noushmehr H. GENE-26. PREDICTIVE SIGNATURE OF MALIGNANT RECURRENCE IN G-CIMP TUMORS Neuro-Oncology. 19: vi98-vi98. DOI: 10.1093/Neuonc/Nox168.400  0.368
2016 Silva TC, Colaprico A, Olsen C, D'Angelo F, Bontempi G, Ceccarelli M, Noushmehr H. TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packages. F1000research. 5: 1542. PMID 28232861 DOI: 10.12688/F1000Research.8923.2  0.442
2016 Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, ... ... Noushmehr H, et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164: 550-563. PMID 26824661 DOI: 10.1016/J.Cell.2015.12.028  0.613
2016 Mota JM, Leite CA, Souza LE, Melo PH, Nascimento DC, de Deus Wagatsuma VM, Temporal J, Figueiredo F, Noushmehr H, Alves-Filho JC, Cunha FQ, Rego EM. Post-sepsis state induces tumor-associated macrophage accumulation through CXCR4/CXCL12 and favors tumor progression in mice. Cancer Immunology Research. PMID 26817997 DOI: 10.1158/2326-6066.Cir-15-0170  0.341
2016 Silva TTC, Colaprico A, Olsen C, D'Angelo F, Bontempi G, Ceccarelli M, Noushmehr H. TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packages [version 1; referees: 1 approved, 1 approved with reservations] F1000research. 5: 1542. DOI: 10.12688/F1000Research.8923.1  0.373
2016 Stetson LC, Souza CFd, Malta TM, Sabedot TS, Ostrom Q, Liao P, Tirapelli DPdC, Neder L, Carlotti CG, Akbani R, Salama S, Poisson L, Brat D, Noushmehr H, Barnholtz-Sloan J. Abstract 780: Multi-omic profiling of gliomas reveals distinct DNA methylation changes at tumor recurrence Cancer Research. 76: 780-780. DOI: 10.1158/1538-7445.Am2016-780  0.528
2016 Malta T, Wiznerowicz M, Noushmehr H. GENT-34. EPIGENOMIC STEMNESS SIGNATURE ASSOCIATED WITH GLIOMA MOLECULAR SUBTYPES Neuro-Oncology. 18: vi81-vi81. DOI: 10.1093/Neuonc/Now212.340  0.313
2016 Sabedot TS, Malta T, Ceccarelli M, Dihn H, Berman B, Noushmehr H. GENT-33. EPIGENETIC ALTERATIONS AT INTERGENIC REGIONS ASSOCIATED WITH PROGRESSION IN A SUBSET OF IDH MUTANT GLIOMAS Neuro-Oncology. 18: vi81-vi81. DOI: 10.1093/Neuonc/Now212.339  0.359
2015 Colaprico A, Silva TC, Olsen C, Garofano L, Cava C, Garolini D, Sabedot TS, Malta TM, Pagnotta SM, Castiglioni I, Ceccarelli M, Bontempi G, Noushmehr H. TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data. Nucleic Acids Research. PMID 26704973 DOI: 10.1093/Nar/Gkv1507  0.435
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.703
2015 Coetzee SG, Shen HC, Hazelett DJ, Lawrenson K, Kuchenbaecker K, Tyrer J, Rhie SK, Levanon K, Karst A, Drapkin R, Ramus SJ, Couch FJ, Offit K, Chenevix-Trench G, ... ... Noushmehr H, et al. Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci. Human Molecular Genetics. 24: 3595-607. PMID 25804953 DOI: 10.1093/Hmg/Ddv101  0.413
2015 Segundo Correia Mota JM, Leite CA, Sousa LE, Wagatsuma VM, Noushmehr H, Cunha FQ, Rego EM. Effect of tumor-associated macrophages on neoplastic progression in sepsis-surviving mice through CXCL12/CXCR4. Journal of Clinical Oncology. 33: e22107-e22107. DOI: 10.1200/Jco.2015.33.15_Suppl.E22107  0.32
2015 Meliso FM, Silva CTd, Coetzee S, Sabedot TS, Noushmehr H, Schneider-Stock R, Jasiulionis MG. Abstract 4767: DNA sequences differentially associated with Sirt1 and Dnmt3b during melanoma progression Cancer Research. 75: 4767-4767. DOI: 10.1158/1538-7445.Am2015-4767  0.448
2015 Barthel FP, Ceccarelli M, Malta TM, Sabedot TS, Salama SR, Pagnotta SM, Murray BA, Morozova O, Newton Y, Brat DJ, Cherniack AD, Zhang H, Poisson L, Cooper L, Rabadan R, ... ... Noushmehr H, et al. GENO-06A PAN-GLIOMA CHARACTERIZATION OF GENOMIC, EPIGENOMIC AND TRANSCRIPTOMIC ACTIVITIES REVEALS NOVEL RELATIONSHIPS BETWEEN HISTOLOGICAL SUBTYPES AND MOLECULAR SIGNATURES Neuro-Oncology. 17: v92.2-v92. DOI: 10.1093/Neuonc/Nov215.06  0.633
2015 Souza C, Malta T, Sabedot T, Stetson L, Tirapelli D, Neder L, Carlotti C, ZenKlusen J, Salama S, Poisson L, Brat D, Barnholtz-Sloan J, Noushmehr H. Epig-16Most Differential Dna Methylation Changes Occur At Candidate Enhancer Elements For Recurrent Lower Grade Glioma And Glioblastoma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov214.16  0.462
2015 Malta T, Sabedot T, Ceccarelli M, Barthel F, Pagnotta S, Iavarone A, Verhaak R, Noushmehr H. EPIG-14EPIGENOMIC (DNA METHYLATION AND EXPRESSION) SIGNATURES DEFINE SUBSETS OF BOTH IDHmut AND IDHwt GLIOMA WITH DISTINCT CLINICAL OUTCOMES Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov214.14  0.465
2014 Lawrenson K, Lee N, Torres HA, Lee JM, Brueggmann D, Rao PN, Noushmehr H, Gayther SA. Src as a novel therapeutic target for endometriosis. Gynecologic Oncology. 135: 100-7. PMID 24972189 DOI: 10.1016/J.Ygyno.2014.06.016  0.356
2014 Rhie SK, Hazelett DJ, Coetzee SG, Yan C, Noushmehr H, Coetzee GA. Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells. Bmc Genomics. 15: 331. PMID 24885402 DOI: 10.1186/1471-2164-15-331  0.357
2014 Hazelett DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL, Coetzee SG, Henderson BE, Noushmehr H, Cozen W, Kote-Jarai Z, Eeles RA, Easton DF, Haiman CA, et al. Comprehensive functional annotation of 77 prostate cancer risk loci. Plos Genetics. 10: e1004102. PMID 24497837 DOI: 10.1371/Journal.Pgen.1004102  0.332
2014 Biancolella M, Fortini BK, Tring S, Plummer SJ, Mendoza-Fandino GA, Hartiala J, Hitchler MJ, Yan C, Schumacher FR, Conti DV, Edlund CK, Noushmehr H, Coetzee SG, Bresalier RS, Ahnen DJ, et al. Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1. Human Molecular Genetics. 23: 2198-209. PMID 24256810 DOI: 10.1093/Hmg/Ddt584  0.303
2014 Shen HC, Coetzee S, Hazelett DJ, Coetzee GA, Noushmehr H, Gayther SA. Abstract 1380: Genome-wide fingerprinting of regulatory chromatin to evaluate the tissue specific origins of high-grade serous ovarian cancer Cancer Research. 74: 1380-1380. DOI: 10.1158/1538-7445.Am2014-1380  0.433
2014 Brennan C, Verhaak R, McKenna A, Campos B, Noushmehr H, Salama S, Zheng S, Chakravarty D, Sanborn J, Berman S, Beroukhim R, Bernard B, Wu C, Genovese G, Shmulevich I, et al. The Somatic Genomic Landscape of Glioblastoma Cell. 157: 753. DOI: 10.1016/J.Cell.2014.04.004  0.542
2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034  0.64
2013 Rhie SK, Coetzee SG, Noushmehr H, Yan C, Kim JM, Haiman CA, Coetzee GA. Comprehensive functional annotation of seventy-one breast cancer risk Loci. Plos One. 8: e63925. PMID 23717510 DOI: 10.1371/Journal.Pone.0063925  0.311
2013 Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, Buckley M, Fridley BL, Tyrer JP, Shen H, Weber R, Karevan R, Larson MC, Song H, Tessier DC, ... ... Noushmehr H, et al. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nature Genetics. 45: 362-70, 370e1-2. PMID 23535730 DOI: 10.1038/Ng.2564  0.38
2013 Permuth-Wey J, Lawrenson K, Shen HC, Velkova A, Tyrer JP, Chen Z, Lin HY, Chen YA, Tsai YY, Qu X, Ramus SJ, Karevan R, Lee J, Lee N, Larson MC, ... ... Noushmehr H, et al. Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nature Communications. 4: 1627. PMID 23535648 DOI: 10.1038/Ncomms2613  0.348
2012 Coetzee SG, Rhie SK, Berman BP, Coetzee GA, Noushmehr H. FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs. Nucleic Acids Research. 40: e139. PMID 22684628 DOI: 10.1093/Nar/Gks542  0.327
2012 Yang X, Noushmehr H, Han H, Andreu-Vieyra C, Liang G, Jones PA. Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions. Plos Genetics. 8: e1002604. PMID 22479200 DOI: 10.1371/Journal.Pgen.1002604  0.411
2012 Little GH, Noushmehr H, Baniwal SK, Berman BP, Coetzee GA, Frenkel B. Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Research. 40: 3538-47. PMID 22187159 DOI: 10.1093/Nar/Gkr1219  0.389
2012 Berman BP, Weisenberger DJ, Aman JF, Hinoue T, Ramjan Z, Liu Y, Noushmehr H, Lange CP, van Dijk CM, Tollenaar RA, Van Den Berg D, Laird PW. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nature Genetics. 44: 40-6. PMID 22120008 DOI: 10.1038/Ng.969  0.767
2012 Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW. Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Research. 22: 271-82. PMID 21659424 DOI: 10.1101/gr.117523.110  0.74
2012 Berman BP, Weisenberger DJ, Hinoue T, Noushmehr H, Liu Y, Aman JF, Hinoue T, Shen H, Malik S, Mahurkar S, Triche T, Ramjan Z, Nicolet CM, Van Den Berg D, Cope L, et al. Exploring the cancer methylome Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-O24  0.777
2012 Noushmehr H, Coetzee SG, Rhie SK, Yan C, Haiman CA, Berman BP, Frenkel B, Coetzee GA. Abstract 1646: Integrative analysis identifies functional prostate cancer risk SNPs in genomic regulatory regions defined as enhancers Cancer Research. 72: 1646-1646. DOI: 10.1158/1538-7445.Am2012-1646  0.372
2011 Hinoue T, Weisenberger DJ, Lange CPE, Noushmehr H, Byun H, Dijk CMv, Pan F, Malik S, Berg DJVD, Shen H, Tollenaar RAEM, Laird PW. Abstract LB-173: Genome-scale analysis of aberrant DNA methylation in colorectal cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-173  0.757
2010 Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 17: 510-22. PMID 20399149 DOI: 10.1016/J.Ccr.2010.03.017  0.64
2010 Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, et al. Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Research. 20: 440-6. PMID 20219944 DOI: 10.1101/Gr.103606.109  0.601
2008 Brown JL, Snir M, Noushmehr H, Kirby M, Hong SK, Elkahloun AG, Feldman B. Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification. Proceedings of the National Academy of Sciences of the United States of America. 105: 12337-42. PMID 18719100 DOI: 10.1073/Pnas.0805589105  0.351
2007 Pei W, Noushmehr H, Costa J, Ouspenskaia MV, Elkahloun AG, Feldman B. An early requirement for maternal FoxH1 during zebrafish gastrulation. Developmental Biology. 310: 10-22. PMID 17719025 DOI: 10.1016/J.Ydbio.2007.07.011  0.312
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