Hitoshi Hashimoto, Ph.D. - Publications

Affiliations: 
Laboratory of Molecular Neuropharmacology  Osaka University, Toyonaka-shi, Ōsaka-fu, Japan 
Website:
http://molpharm.umin.jp/index-e.html

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, ... ... Hashimoto H, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. Elife. 12. PMID 38529532 DOI: 10.7554/eLife.89376  0.476
2020 Kawaguchi C, Shintani N, Hayata-Takano A, Hatanaka M, Kuromi A, Nakamura R, Yamano Y, Shintani Y, Nagai K, Tsuchiya S, Sugimoto Y, Ichikawa A, Okuno Y, Urade Y, Hirai H, ... ... Hashimoto H, et al. Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice. Communications Biology. 3: 557. PMID 33033338 DOI: 10.1038/s42003-020-01281-w  0.458
2020 Takeuchi S, Kawanai T, Yamauchi R, Chen L, Miyaoka T, Yamada M, Asano S, Hayata-Takano A, Nakazawa T, Yano K, Horiguchi N, Nakagawa S, Takuma K, Waschek JA, Hashimoto H, et al. Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism. Frontiers in Neuroscience. 14: 521. PMID 32581681 DOI: 10.3389/Fnins.2020.00521  0.376
2020 Nguyen TT, Kambe Y, Kurihara T, Nakamachi T, Shintani N, Hashimoto H, Miyata A. Pituitary Adenylate Cyclase-Activating Polypeptide in the Ventromedial Hypothalamus Is Responsible for Food Intake Behavior by Modulating the Expression of Agouti-Related Peptide in Mice. Molecular Neurobiology. PMID 31927724 DOI: 10.1007/S12035-019-01864-7  0.351
2019 Fulop DB, Humli V, Szepesy J, Ott V, Reglodi D, Gaszner B, Nemeth A, Szirmai A, Tamas L, Hashimoto H, Zelles T, Tamas A. Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice. Scientific Reports. 9: 14598. PMID 31601840 DOI: 10.1038/S41598-019-50775-Z  0.395
2019 Baba M, Yokoyama K, Seiriki K, Naka Y, Matsumura K, Kondo M, Yamamoto K, Hayashida M, Kasai A, Ago Y, Nagayasu K, Hayata-Takano A, Takahashi A, Yamaguchi S, Mori D, ... ... Hashimoto H, et al. Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31216562 DOI: 10.1038/S41386-019-0441-5  0.313
2019 Hayata-Takano A, Kamo T, Kijima H, Seiriki K, Ogata K, Ago Y, Nakazawa T, Shintani Y, Higashino K, Nagayasu K, Shintani N, Kasai A, Waschek JA, Hashimoto H. Pituitary adenylate cyclase-activating polypeptide modulates dendritic spine maturation and morphogenesis via microRNA-132 upregulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30886013 DOI: 10.1523/Jneurosci.2468-18.2019  0.327
2019 Ivic I, Balasko M, Fulop BD, Hashimoto H, Toth G, Tamas A, Juhasz T, Koller A, Reglodi D, Solymár M. VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice. Plos One. 14: e0211433. PMID 30682157 DOI: 10.1371/Journal.Pone.0211433  0.389
2019 Fulop BD, Sandor B, Szentleleky E, Karanyicz E, Reglodi D, Gaszner B, Zakany R, Hashimoto H, Juhasz T, Tamas A. Altered Notch Signaling in Developing Molar Teeth of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)-Deficient Mice Journal of Molecular Neuroscience. 68: 377-388. PMID 30094580 DOI: 10.1007/S12031-018-1146-7  0.411
2018 Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H. mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model. Pharmacology, Biochemistry, and Behavior. 176: 1-5. PMID 30419271 DOI: 10.1016/J.Pbb.2018.11.003  0.32
2018 Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Andoh C, Nagai Y, Kinoshita H, Kawai H, Shibui N, Liu B, Hewinson J, Shirakawa H, Nakagawa T, Hashimoto H, Kasparov S, et al. Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30377380 DOI: 10.1038/S41386-018-0254-Y  0.347
2018 Reglodi D, Jungling A, Longuespée R, Kriegsmann J, Casadonte R, Kriegsmann M, Juhasz T, Bardosi S, Tamas A, Fulop BD, Kovacs K, Nagy Z, Sparks J, Miseta A, Mazzucchelli G, ... Hashimoto H, et al. Accelerated pre-senile systemic amyloidosis in PACAP knockout mice - a protective role of PACAP in age-related degenerative processes. The Journal of Pathology. PMID 29774542 DOI: 10.1002/Path.5100  0.349
2017 Inoue N, Hirouchi T, Kasai A, Higashi S, Hiraki N, Tanaka S, Nakazawa T, Nunomura K, Lin B, Omori A, Hayata-Takano A, Kim YJ, Doi T, Baba A, Hashimoto H, et al. Unbiased compound screening with a reporter gene assay highlights the role of p13 in the cardiac cellular stress response. Biochemical and Biophysical Research Communications. PMID 29180011 DOI: 10.1016/J.Bbrc.2017.11.116  0.451
2017 Ivic I, Solymar M, Fulop BD, Hashimoto H, Toth G, Tamas A, Juhasz T, Koller A, Reglodi D. Aging-Induced Modulation of Pituitary Adenylate Cyclase-Activating Peptide- and Vasoactive Intestinal Peptide-Induced Vasomotor Responses in the Arteries of Mice. Journal of Vascular Research. 54: 359-366. PMID 29131060 DOI: 10.1159/000481781  0.358
2017 Reglodi D, Cseh S, Somoskoi B, Fulop B, Szentleleky E, Szegeczki V, Kovacs A, Varga A, Kiss P, Hashimoto H, Tamas A, Bardosi A, Manavalan S, Bako E, Zakany R, et al. Disturbed spermatogenic signaling in PACAP deficient mice. Reproduction (Cambridge, England). PMID 29101268 DOI: 10.1530/Rep-17-0470  0.419
2017 Ago Y, Hayata-Takano A, Kawanai T, Yamauchi R, Takeuchi S, Cushman JD, Rajbhandari AK, Fanselow MS, Hashimoto H, Waschek JA. Impaired extinction of cued fear memory and abnormal dendritic morphology in the prelimbic and infralimbic cortices in VPAC2 receptor (VIPR2)-deficient mice. Neurobiology of Learning and Memory. PMID 29030297 DOI: 10.1016/J.Nlm.2017.10.010  0.36
2017 Hara Y, Ago Y, Higuchi M, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K. Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism. Hormones and Behavior. PMID 28942000 DOI: 10.1016/J.Yhbeh.2017.09.013  0.332
2017 Hara Y, Ago Y, Taruta A, Hasebe S, Kawase H, Tanabe W, Tsukada S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K. Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice. Psychopharmacology. PMID 28798977 DOI: 10.1007/S00213-017-4703-9  0.328
2017 Yamaguchi H, Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K. Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice. Behavioural Brain Research. PMID 28655565 DOI: 10.1016/J.Bbr.2017.06.035  0.369
2017 Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue KI, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, ... ... Hashimoto H, et al. High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates. Neuron. 94: 1085-1100.e6. PMID 28641108 DOI: 10.1016/J.Neuron.2017.05.017  0.423
2017 Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T. Psychopharmacology of combined activation of the serotonin1A and σ1 receptors. European Journal of Pharmacology. PMID 28529139 DOI: 10.1016/J.Ejphar.2017.05.035  0.362
2017 Ivic I, Fulop BD, Juhasz T, Reglodi D, Toth G, Hashimoto H, Tamas A, Koller A. Backup Mechanisms Maintain PACAP/VIP-Induced Arterial Relaxations in Pituitary Adenylate Cyclase-Activating Polypeptide-Deficient Mice. Journal of Vascular Research. 54: 180-192. PMID 28490016 DOI: 10.1159/000457798  0.424
2017 Farkas J, Kovács LÁ, Gáspár L, Nafz A, Gaszner T, Ujvári B, Kormos V, Csernus V, Hashimoto H, Reglődi D, Gaszner B. Construct and face validity of a new model for the three-hit theory of depression using PACAP mutant mice on CD1 background. Neuroscience. PMID 28450265 DOI: 10.1016/J.Neuroscience.2017.04.019  0.375
2017 Fujita Y, Masuda K, Bando M, Nakato R, Katou Y, Tanaka T, Nakayama M, Takao K, Miyakawa T, Tanaka T, Ago Y, Hashimoto H, Shirahige K, Yamashita T. Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior. The Journal of Experimental Medicine. PMID 28408410 DOI: 10.1084/Jem.20161517  0.386
2017 Farkas J, Sandor B, Tamas A, Kiss P, Hashimoto H, Nagy AD, Fulop BD, Juhasz T, Manavalan S, Reglodi D. Early Neurobehavioral Development of Mice Lacking Endogenous PACAP. Journal of Molecular Neuroscience : Mn. PMID 28168413 DOI: 10.1007/S12031-017-0887-Z  0.398
2016 Nakata M, Zhang B, Yang Y, Okada T, Shintani N, Hashimoto H, Yada T. High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance. Journal of Diabetes Research. 2016: 9321395. PMID 28044141 DOI: 10.1155/2016/9321395  0.37
2016 Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T. Role of prefrontal serotonergic and dopaminergic systems in encounter-induced hyperactivity in methamphetamine-sensitized mice. The International Journal of Neuropsychopharmacology. PMID 28034961 DOI: 10.1093/Ijnp/Pyw115  0.381
2016 Hasebe S, Ago Y, Watabe Y, Oka S, Hiramatsu N, Tanaka T, Umehara C, Hashimoto H, Takuma K, Matsuda T. Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for σ1 receptors in picrotoxin-treated mice. British Journal of Pharmacology. PMID 27987210 DOI: 10.1111/Bph.13692  0.385
2016 Lacaille H, Duterte-Boucher D, Vaudry H, Zerdoumi Y, Flaman JM, Hashimoto H, Vaudry D. PACAP Protects the Adolescent and Adult Mice Brain from Ethanol Toxicity and Modulates Distinct Sets of Genes Regulating Similar Networks. Molecular Neurobiology. PMID 27826748 DOI: 10.1007/S12035-016-0204-9  0.363
2016 Seiriki K, Kasai A, Kuwaki T, Nakazawa T, Yamaguchi S, Hashimoto H. Critical involvement of the orbitofrontal cortex in hyperlocomotion induced by NMDA receptor blockade in mice. Biochemical and Biophysical Research Communications. PMID 27793672 DOI: 10.1016/J.Bbrc.2016.10.089  0.363
2016 Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, ... ... Hashimoto H, et al. Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction. Behavioural Brain Research. PMID 27481693 DOI: 10.1016/J.Bbr.2016.07.050  0.469
2016 Nakamachi T, Ohtaki H, Seki T, Yofu S, Kagami N, Hashimoto H, Shintani N, Baba A, Mark L, Lanekoff I, Kiss P, Farkas J, Reglodi D, Shioda S. PACAP suppresses dry eye signs by stimulating tear secretion. Nature Communications. 7: 12034. PMID 27345595 DOI: 10.1038/Ncomms12034  0.475
2016 Ago Y, Hasebe S, Hiramatsu N, Mori K, Watabe Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T. Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency. Psychopharmacology. PMID 27339616 DOI: 10.1007/S00213-016-4353-3  0.32
2016 Kawanai T, Ago Y, Watanabe R, Inoue A, Taruta A, Onaka Y, Hasebe S, Hashimoto H, Matsuda T, Takuma K. Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation. Neurochemical Research. PMID 27300699 DOI: 10.1007/S11064-016-1969-Y  0.301
2016 Kormos V, Gáspár L, Kovács L, Farkas J, Gaszner T, Csernus V, Balogh A, Hashimoto H, Reglődi D, Helyes Z, Gaszner B. Reduced response to chronic mild stress in PACAP mutant mice is associated with blunted FosB expression in limbic forebrain and brainstem centers. Neuroscience. PMID 27282087 DOI: 10.1016/J.Neuroscience.2016.06.004  0.399
2016 Sandor B, Fintor K, Reglodi D, Fulop DB, Helyes Z, Szanto I, Nagy P, Hashimoto H, Tamas A. Structural and Morphometric Comparison of Lower Incisors in PACAP-Deficient and Wild-Type Mice. Journal of Molecular Neuroscience : Mn. 59: 300-8. PMID 27154515 DOI: 10.1007/S12031-016-0765-0  0.387
2016 Egri P, Fekete C, Dénes Á, Reglődi D, Hashimoto H, Fülöp BD, Gereben B. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Regulates the Hypothalamo-Pituitary-Thyroid (HPT) Axis via Type 2 Deiodinase in Male Mice. Endocrinology. 157: 2356-66. PMID 27046436 DOI: 10.1210/En.2016-1043  0.354
2016 Fujiwara K, Fujita Y, Kasai A, Onaka Y, Hashimoto H, Okada H, Yamashita T. Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse. Translational Psychiatry. 6: e766. PMID 27023172 DOI: 10.1038/Tp.2016.31  0.385
2016 Xu Z, Ohtaki H, Watanabe J, Miyamoto K, Murai N, Sasaki S, Matsumoto M, Hashimoto H, Hiraizumi Y, Numazawa S, Shioda S. Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor. Scientific Reports. 6: 22373. PMID 26925806 DOI: 10.1038/Srep22373  0.401
2016 Matsumoto M, Nakamachi T, Watanabe J, Sugiyama K, Ohtaki H, Murai N, Sasaki S, Xu Z, Hashimoto H, Seki T, Miyazaki A, Shioda S. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke. Journal of Molecular Neuroscience : Mn. PMID 26910758 DOI: 10.1007/S12031-016-0731-X  0.385
2016 Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda-Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, ... ... Hashimoto H, et al. Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders. Nature Communications. 7: 10594. PMID 26839058 DOI: 10.1038/Ncomms10594  0.382
2016 Ago Y, Hayata A, Kawanai T, Yamauchi R, Waschek J, Hashimoto H. PM360. Overactivation of the VPAC2 receptor during the early postnatal period causes prefrontal synaptic abnormalities and cognitive dysfunction in mice. The International Journal of Neuropsychopharmacology. 19: 31-32. DOI: 10.1093/Ijnp/Pyw041.360  0.332
2015 Ikeda K, Tomimoto S, Tsuchiya S, Hamagami KI, Shintani N, Sugimoto Y, Ichikawa A, Kasai A, Nakazawa T, Nagayasu K, Hayata-Takano A, Baba A, Hashimoto H. Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice. Biochemistry and Biophysics Reports. 2: 179-183. PMID 29124161 DOI: 10.1016/J.Bbrep.2015.06.006  0.516
2015 Hara Y, Ago Y, Taruta A, Katashiba K, Hasebe S, Takano E, Onaka Y, Hashimoto H, Matsuda T, Takuma K. Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism. Autism Research : Official Journal of the International Society For Autism Research. PMID 26714434 DOI: 10.1002/Aur.1596  0.366
2015 Higashino K, Ago Y, Umeki T, Hasebe S, Onaka Y, Hashimoto H, Takuma K, Matsuda T. Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice. Psychopharmacology. PMID 26518025 DOI: 10.1007/S00213-015-4123-7  0.388
2015 Kawanai T, Taruta A, Inoue A, Watanabe R, Ago Y, Hashimoto H, Hasebe S, Ooi Y, Takuma K, Matsuda T. Decreased expression of hippocampal Na⁺/Ca²⁺ exchanger isoform-1 by pentylenetetrazole kindling in mice. Epilepsy Research. 115: 109-12. PMID 26220386 DOI: 10.1016/J.Eplepsyres.2015.06.002  0.302
2015 Ago Y, Hasebe S, Nishiyama S, Oka S, Onaka Y, Hashimoto H, Takuma K, Matsuda T. The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 26025781 DOI: 10.1093/Ijnp/Pyv062  0.317
2015 Hasebe S, Ago Y, Nishiyama S, Oka S, Hashimoto H, Takuma K, Matsuda T. Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice. Behavioural Pharmacology. 26: 681-90. PMID 25932719 DOI: 10.1097/Fbp.0000000000000140  0.3
2015 Higashi S, Katagi K, Shintani N, Ikeda K, Sugimoto Y, Tsuchiya S, Inoue N, Tanaka S, Koumoto M, Kasai A, Nakazawa T, Hayata-Takano A, Hamagami K, Tomimoto S, Yoshida T, ... ... Hashimoto H, et al. p13 overexpression in pancreatic β-cells ameliorates type 2 diabetes in high-fat-fed mice. Biochemical and Biophysical Research Communications. 461: 612-7. PMID 25912136 DOI: 10.1016/J.Bbrc.2015.04.074  0.487
2015 Hara Y, Takuma K, Takano E, Katashiba K, Taruta A, Higashino K, Hashimoto H, Ago Y, Matsuda T. Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model. Behavioural Brain Research. 289: 39-47. PMID 25907743 DOI: 10.1016/J.Bbr.2015.04.022  0.312
2015 Helyes Z, Kun J, Dobrosi N, Sándor K, Németh J, Perkecz A, Pintér E, Szabadfi K, Gaszner B, Tékus V, Szolcsányi J, Steinhoff M, Hashimoto H, Regl?di D, Bíró T. Pituitary Adenylate Cyclase-Activating Polypeptide Is Upregulated in Murine Skin Inflammation and Mediates Transient Receptor Potential Vanilloid-1-Induced Neurogenic Edema. The Journal of Investigative Dermatology. PMID 25905588 DOI: 10.1038/Jid.2015.156  0.332
2015 Tsumuraya T, Ohtaki H, Song D, Sato A, Watanabe J, Hiraizumi Y, Nakamachi T, Xu Z, Dohi K, Hashimoto H, Atsumi T, Shioda S. Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP). Journal of Neuroinflammation. 12: 35. PMID 25889720 DOI: 10.1186/S12974-015-0252-5  0.383
2015 Shibasaki Y, Hayata-Takano A, Hazama K, Nakazawa T, Shintani N, Kasai A, Nagayasu K, Hashimoto R, Tanida M, Katayama T, Matsuzaki S, Yamada K, Taniike M, Onaka Y, Ago Y, ... ... Hashimoto H, et al. Atomoxetine reverses locomotor hyperactivity, impaired novel object recognition, and prepulse inhibition impairment in mice lacking pituitary adenylate cyclase-activating polypeptide. Neuroscience. 297: 95-104. PMID 25841321 DOI: 10.1016/J.Neuroscience.2015.03.062  0.533
2015 Ogata K, Shintani N, Hayata-Takano A, Kamo T, Higashi S, Seiriki K, Momosaki H, Vaudry D, Vaudry H, Galas L, Kasai A, Nagayasu K, Nakazawa T, Hashimoto R, Ago Y, ... ... Hashimoto H, et al. PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF. Plos One. 10: e0120526. PMID 25807538 DOI: 10.1371/Journal.Pone.0120526  0.457
2015 Hasebe S, Hiramatsu N, Ago Y, Mori K, Watabe Y, Hashimoto H, Takuma K, Matsuda T. Role of the 5-HT1A autoreceptor in the enhancement of fluvoxamine-induced increases in prefrontal dopamine release by adrenalectomy/castration in mice. Journal of Pharmacological Sciences. 127: 232-5. PMID 25727963 DOI: 10.1016/J.Jphs.2015.01.001  0.344
2015 Schulze W, Hayata-Takano A, Kamo T, Nakazawa T, Nagayasu K, Kasai A, Seiriki K, Shintani N, Ago Y, Farfan C, Hashimoto R, Baba A, Hashimoto H. Simultaneous neuron- and astrocyte-specific fluorescent marking. Biochemical and Biophysical Research Communications. 459: 81-6. PMID 25721661 DOI: 10.1016/J.Bbrc.2015.02.073  0.45
2015 Onaka Y, Shintani N, Nakazawa T, Haba R, Ago Y, Wang H, Kanoh T, Hayata-Takano A, Hirai H, Nagata KY, Nakamura M, Hashimoto R, Matsuda T, Waschek JA, Kasai A, ... ... Hashimoto H, et al. CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice. Behavioural Brain Research. 284: 131-7. PMID 25698598 DOI: 10.1016/J.Bbr.2015.02.013  0.505
2015 Ota Y, Ago Y, Tanaka T, Hasebe S, Toratani Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T. Anxiolytic-like effects of restraint during the dark cycle in adolescent mice. Behavioural Brain Research. 284: 103-11. PMID 25687845 DOI: 10.1016/J.Bbr.2015.02.010  0.322
2015 Ago Y, Condro MC, Tan YV, Ghiani CA, Colwell CS, Cushman JD, Fanselow MS, Hashimoto H, Waschek JA. Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist. Psychopharmacology. 232: 2181-9. PMID 25575489 DOI: 10.1007/S00213-014-3848-Z  0.328
2015 Yamasaki A, Kasai A, Toi A, Kurita M, Kimoto S, Hayata-Takano A, Nakazawa T, Nagayasu K, Shintani N, Hashimoto R, Ito A, Meltzer HY, Ago Y, Waschek JA, Onaka Y, ... ... Hashimoto H, et al. Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro. Journal of Neurochemistry. 132: 418-28. PMID 25421849 DOI: 10.1111/Jnc.12999  0.489
2015 Ogata K, Shintani N, Hayata-Takano A, Kamo T, Higashi S, Seiriki K, Momosaki H, Vaudry D, Vaudry H, Galas L, Kasai A, Nagayasu K, Nakazawa T, Hashimoto R, Ago Y, ... ... Hashimoto H, et al. The effect of TrkB receptor inhibitor K252a on neurite outgrowth. Plos One. DOI: 10.1371/Journal.Pone.0120526.G005  0.457
2014 Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, ... ... Hashimoto H, et al. Behavioral characterization of mice overexpressing human dysbindin-1. Molecular Brain. 7: 74. PMID 25298178 DOI: 10.1186/S13041-014-0074-X  0.426
2014 Takuma K, Hara Y, Kataoka S, Kawanai T, Maeda Y, Watanabe R, Takano E, Hayata-Takano A, Hashimoto H, Ago Y, Matsuda T. Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. Pharmacology, Biochemistry, and Behavior. 126: 43-9. PMID 25240644 DOI: 10.1016/J.Pbb.2014.08.013  0.324
2014 Sandor B, Fintor K, Felszeghy S, Juhasz T, Reglodi D, Mark L, Kiss P, Jungling A, Fulop BD, Nagy AD, Hashimoto H, Zakany R, Nagy A, Tamas A. Structural and morphometric comparison of the molar teeth in pre-eruptive developmental stage of PACAP-deficient and wild-type mice. Journal of Molecular Neuroscience : Mn. 54: 331-41. PMID 25112419 DOI: 10.1007/S12031-014-0392-6  0.404
2014 Botz B, Bölcskei K, Kereskai L, Kovács M, Németh T, Szigeti K, Horváth I, Máthé D, Kovács N, Hashimoto H, ReglÅ‘di D, Szolcsányi J, Pintér E, Mócsai A, Helyes Z. Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2739-50. PMID 25048575 DOI: 10.1002/Art.38772  0.377
2014 Takuma K, Maeda Y, Ago Y, Ishihama T, Takemoto K, Nakagawa A, Shintani N, Hashimoto H, Baba A, Matsuda T. An enriched environment ameliorates memory impairments in PACAP-deficient mice. Behavioural Brain Research. 272: 269-78. PMID 25014004 DOI: 10.1016/J.Bbr.2014.07.005  0.516
2014 Banki E, Pakai E, Gaszner B, Zsiboras C, Czett A, Bhuddi PR, Hashimoto H, Toth G, Tamas A, Reglodi D, Garami A. Characterization of the thermoregulatory response to pituitary adenylate cyclase-activating polypeptide in rodents. Journal of Molecular Neuroscience : Mn. 54: 543-54. PMID 24994541 DOI: 10.1007/S12031-014-0361-0  0.387
2014 Maasz G, Pirger Z, Reglodi D, Petrovics D, Schmidt J, Kiss P, Rivnyak A, Hashimoto H, Avar P, Jambor E, Tamas A, Gaszner B, Mark L. Comparative protein composition of the brains of PACAP-deficient mice using mass spectrometry-based proteomic analysis. Journal of Molecular Neuroscience : Mn. 54: 310-9. PMID 24643519 DOI: 10.1007/S12031-014-0264-0  0.402
2014 Hazama K, Hayata-Takano A, Uetsuki K, Kasai A, Encho N, Shintani N, Nagayasu K, Hashimoto R, Reglodi D, Miyakawa T, Nakazawa T, Baba A, Hashimoto H. Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice. Plos One. 9: e89153. PMID 24586556 DOI: 10.1371/Journal.Pone.0089153  0.57
2014 Haba R, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, Hayata A, Hirai H, Nagata KY, Nakamura M, Kasai A, Hashimoto R, Nagayasu K, Nakazawa T, Hashimoto H, et al. Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2514-23. PMID 24523542 DOI: 10.1523/Jneurosci.1407-13.2014  0.516
2014 Nemeth A, Szabadfi K, Fulop B, Reglodi D, Kiss P, Farkas J, Szalontai B, Gabriel R, Hashimoto H, Tamas A. Examination of calcium-binding protein expression in the inner ear of wild-type, heterozygous and homozygous pituitary adenylate cyclase-activating polypeptide (PACAP)-knockout mice in kanamycin-induced ototoxicity. Neurotoxicity Research. 25: 57-67. PMID 24155155 DOI: 10.1007/S12640-013-9428-X  0.381
2013 Hayata-Takano A, Seiriki K, Tajiri M, Ogata K, Shintani N, Baba A, Hashimoto H. [Pituitary adenylate cyclase-activating polypeptide(PACAP) plays significant roles in mental function and neuronal development]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 33: 73-5. PMID 25314749  0.369
2013 Botz B, Imreh A, Sándor K, Elekes K, Szolcsányi J, ReglÅ‘di D, Quinn JP, Stewart J, Zimmer A, Hashimoto H, Helyes Z. Role of Pituitary Adenylate-Cyclase Activating Polypeptide and Tac1 gene derived tachykinins in sensory, motor and vascular functions under normal and neuropathic conditions. Peptides. 43: 105-12. PMID 23499760 DOI: 10.1016/J.Peptides.2013.03.003  0.373
2013 Inoue H, Shintani N, Sakurai Y, Higashi S, Hayata-Takano A, Baba A, Hashimoto H. PACAP Inhibits β-cell Mass Expansion in a Mouse Model of Type II Diabetes: Persistent Suppressive Effects on Islet Density. Frontiers in Endocrinology. 4: 27. PMID 23483824 DOI: 10.3389/Fendo.2013.00027  0.532
2013 Tanida M, Hayata A, Shintani N, Yamamoto N, Kurata Y, Shibamoto T, Morgan DA, Rahmouni K, Hashimoto H. Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner. Neuroscience. 238: 297-304. PMID 23454538 DOI: 10.1016/J.Neuroscience.2013.02.016  0.381
2013 Ago Y, Hiramatsu N, Ishihama T, Hazama K, Hayata-Takano A, Shibasaki Y, Shintani N, Hashimoto H, Kawasaki T, Onoe H, Chaki S, Nakazato A, Baba A, Takuma K, Matsuda T. The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide. Behavioural Pharmacology. 24: 74-7. PMID 23268987 DOI: 10.1097/Fbp.0B013E32835Cf3E5  0.532
2013 Arata S, Nakamachi T, Onimaru H, Hashimoto H, Shioda S. Impaired response to hypoxia in the respiratory center is a major cause of neonatal death of the PACAP-knockout mouse. The European Journal of Neuroscience. 37: 407-16. PMID 23136967 DOI: 10.1111/Ejn.12054  0.412
2013 Tóth ZE, Heinzlmann A, Hashimoto H, Köves K. Distribution of secretin receptors in the rat central nervous system: an in situ hybridization study. Journal of Molecular Neuroscience : Mn. 50: 172-8. PMID 23065333 DOI: 10.1007/S12031-012-9895-1  0.324
2013 Ago Y, Yano K, Araki R, Hiramatsu N, Kita Y, Kawasaki T, Onoe H, Chaki S, Nakazato A, Hashimoto H, Baba A, Takuma K, Matsuda T. Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice. Neuropharmacology. 65: 29-38. PMID 23022081 DOI: 10.1016/J.Neuropharm.2012.09.008  0.51
2012 Hattori S, Takao K, Tanda K, Toyama K, Shintani N, Baba A, Hashimoto H, Miyakawa T. Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice. Frontiers in Behavioral Neuroscience. 6: 58. PMID 23060763 DOI: 10.3389/Fnbeh.2012.00058  0.561
2012 Tajiri M, Hayata-Takano A, Seiriki K, Ogata K, Hazama K, Shintani N, Baba A, Hashimoto H. Serotonin 5-HT(7) receptor blockade reverses behavioral abnormalities in PACAP-deficient mice and receptor activation promotes neurite extension in primary embryonic hippocampal neurons: therapeutic implications for psychiatric disorders. Journal of Molecular Neuroscience : Mn. 48: 473-81. PMID 22843252 DOI: 10.1007/S12031-012-9861-Y  0.534
2012 Heinzlmann A, Kiss G, Tóth ZE, Dochnal R, Pál Á, Sipos I, Manczinger M, Szabó G, Hashimoto H, Köves K. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. Journal of Molecular Neuroscience : Mn. 48: 558-64. PMID 22752505 DOI: 10.1007/S12031-012-9839-9  0.329
2012 Tsuchikawa D, Nakamachi T, Tsuchida M, Wada Y, Hori M, Farkas J, Yoshikawa A, Kagami N, Imai N, Shintani N, Hashimoto H, Atsumi T, Shioda S. Neuroprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on spinal cord injury. Journal of Molecular Neuroscience : Mn. 48: 508-17. PMID 22674051 DOI: 10.1007/S12031-012-9817-2  0.362
2012 Kawasaki T, Marumo T, Shirakami K, Mori T, Doi H, Suzuki M, Watanabe Y, Chaki S, Nakazato A, Ago Y, Hashimoto H, Matsuda T, Baba A, Onoe H. Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1737-46. PMID 22669478 DOI: 10.1038/Jcbfm.2012.68  0.431
2012 Brubel R, Kiss P, Vincze A, Varga A, Varnagy A, Bodis J, Mark L, Jambor E, Maasz G, Hashimoto H, Helyes Z, Toth G, Tamas A, Koppan M, Reglodi D. Effects of pituitary adenylate cyclase activating polypeptide on human sperm motility. Journal of Molecular Neuroscience : Mn. 48: 623-30. PMID 22638857 DOI: 10.1007/S12031-012-9806-5  0.331
2012 Reglodi D, Kiss P, Szabadfi K, Atlasz T, Gabriel R, Horvath G, Szakaly P, Sandor B, Lubics A, Laszlo E, Farkas J, Matkovits A, Brubel R, Hashimoto H, Ferencz A, et al. PACAP is an endogenous protective factor-insights from PACAP-deficient mice. Journal of Molecular Neuroscience : Mn. 48: 482-92. PMID 22528455 DOI: 10.1007/S12031-012-9762-0  0.399
2012 Sakurai Y, Inoue H, Shintani N, Arimori A, Hamagami K, Hayata-Takano A, Baba A, Hashimoto H. Compensatory recovery of blood glucose levels in KKA(y) mice fed a high-fat diet: insulin-sparing effects of PACAP overexpression in β cells. Journal of Molecular Neuroscience : Mn. 48: 647-53. PMID 22477644 DOI: 10.1007/S12031-012-9758-9  0.485
2012 Shimada T, Takai Y, Shinohara K, Yamasaki A, Tominaga-Yoshino K, Ogura A, Toi A, Asano K, Shintani N, Hayata-Takano A, Baba A, Hashimoto H. A simplified method to generate serotonergic neurons from mouse embryonic stem and induced pluripotent stem cells. Journal of Neurochemistry. 122: 81-93. PMID 22404309 DOI: 10.1111/J.1471-4159.2012.07724.X  0.458
2012 Ago Y, Araki R, Yano K, Kawasaki T, Chaki S, Nakazato A, Onoe H, Hashimoto H, Baba A, Takuma K, Matsuda T. The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses isolation rearing-induced abnormal behaviors in mice. Journal of Pharmacological Sciences. 118: 295-8. PMID 22293290 DOI: 10.1254/Jphs.11200Sc  0.534
2012 Haba R, Shintani N, Onaka Y, Wang H, Takenaga R, Hayata A, Baba A, Hashimoto H. Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala. Behavioural Brain Research. 228: 423-31. PMID 22209851 DOI: 10.1016/J.Bbr.2011.12.027  0.46
2012 Tamas A, Szabadfi K, Nemeth A, Fulop B, Kiss P, Atlasz T, Gabriel R, Hashimoto H, Baba A, Shintani N, Helyes Z, Reglodi D. Comparative examination of inner ear in wild type and pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice. Neurotoxicity Research. 21: 435-44. PMID 22203609 DOI: 10.1007/S12640-011-9298-Z  0.544
2012 Gaszner B, Kormos V, Kozicz T, Hashimoto H, Reglodi D, Helyes Z. The behavioral phenotype of pituitary adenylate-cyclase activating polypeptide-deficient mice in anxiety and depression tests is accompanied by blunted c-Fos expression in the bed nucleus of the stria terminalis, central projecting Edinger-Westphal nucleus, ventral lateral septum, and dorsal raphe nucleus Neuroscience. 202: 283-299. PMID 22178610 DOI: 10.1016/J.Neuroscience.2011.11.046  0.379
2012 Markovics A, Kormos V, Gaszner B, Lashgarara A, Szoke E, Sandor K, Szabadfi K, Tuka B, Tajti J, Szolcsanyi J, Pinter E, Hashimoto H, Kun J, Reglodi D, Helyes Z. Pituitary adenylate cyclase-activating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice. Neurobiology of Disease. 45: 633-44. PMID 22033344 DOI: 10.1016/J.Nbd.2011.10.010  0.435
2012 Szabadfi K, Atlasz T, Kiss P, Danyadi B, Tamas A, Helyes Z, Hashimoto H, Shintani N, Baba A, Toth G, Gabriel R, Reglodi D. Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) are more susceptible to retinal ischemic injury in vivo. Neurotoxicity Research. 21: 41-8. PMID 21717232 DOI: 10.1007/S12640-011-9254-Y  0.496
2012 Nakamachi T, Aizawa Y, Ohtaki H, Yofu S, Wada Y, Seki T, Arata NS, Shintani, Hashimoto H, Baba A, Shioda S. PACAP stimulates tear secretion via AQP5 translocation in mouse Regulatory Peptides. 177. DOI: 10.1016/J.Regpep.2012.05.059  0.448
2011 Vincze A, Reglodi D, Helyes Z, Hashimoto H, Shintani N, Abrahám H. Role of endogenous pituitary adenylate cyclase activating polypeptide (PACAP) in myelination of the rodent brain: lessons from PACAP-deficient mice. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 29: 923-35. PMID 21726625 DOI: 10.1016/J.Ijdevneu.2011.06.008  0.342
2011 Elekes K, Sandor K, Moricz A, Kereskai L, Kemeny A, Szoke E, Perkecz A, Reglodi D, Hashimoto H, Pinter E, Szolcsanyi J, Helyes Z. Pituitary adenylate cyclase-activating polypeptide plays an anti-inflammatory role in endotoxin-induced airway inflammation: in vivo study with gene-deleted mice. Peptides. 32: 1439-46. PMID 21605612 DOI: 10.1016/J.Peptides.2011.05.008  0.365
2011 Hashimoto H, Shintani N, Tanida M, Hayata A, Hashimoto R, Baba A. PACAP is implicated in the stress axes. Current Pharmaceutical Design. 17: 985-9. PMID 21524255 DOI: 10.2174/138161211795589382  0.469
2011 Ago Y, Araki R, Yano K, Hiramatsu N, Kawasaki T, Chaki S, Nakazato A, Onoe H, Hashimoto H, Baba A, Takuma K, Matsuda T. Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission. Psychopharmacology. 217: 443-52. PMID 21487651 DOI: 10.1007/S00213-011-2295-3  0.508
2011 Tsukiyama N, Saida Y, Kakuda M, Shintani N, Hayata A, Morita Y, Tanida M, Tajiri M, Hazama K, Ogata K, Hashimoto H, Baba A. PACAP centrally mediates emotional stress-induced corticosterone responses in mice. Stress (Amsterdam, Netherlands). 14: 368-75. PMID 21438773 DOI: 10.3109/10253890.2010.544345  0.539
2011 Hashimoto R, Yasuda Y, Ohi K, Fukumoto M, Yamamori H, Shintani N, Hashimoto H, Baba A, Takeda M. [Translational research for mental disorder -schizophrenia]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 137: 79-82. PMID 21321456 DOI: 10.1254/Fpj.137.79  0.393
2011 Szakaly P, Laszlo E, Kovacs K, Racz B, Horvath G, Ferencz A, Lubics A, Kiss P, Tamas A, Brubel R, Opper B, Baba A, Hashimoto H, Farkas J, Matkovits A, et al. Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) show increased susceptibility to in vivo renal ischemia/reperfusion injury. Neuropeptides. 45: 113-21. PMID 21211837 DOI: 10.1016/J.Npep.2010.12.003  0.513
2011 Ago Y, Yoneyama M, Ishihama T, Kataoka S, Kawada K, Tanaka T, Ogita K, Shintani N, Hashimoto H, Baba A, Takuma K, Matsuda T. Role of endogenous pituitary adenylate cyclase-activating polypeptide in adult hippocampal neurogenesis. Neuroscience. 172: 554-61. PMID 20974227 DOI: 10.1016/J.Neuroscience.2010.10.044  0.543
2011 Kawasaki T, Ago Y, Yano K, Araki R, Washida Y, Onoe H, Chaki S, Nakazato A, Hashimoto H, Baba A, Takuma K, Matsuda T. Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice. Neuropharmacology. 60: 397-404. PMID 20970439 DOI: 10.1016/J.Neuropharm.2010.10.009  0.514
2011 Endo K, Nakamachi T, Seki T, Kagami N, Wada Y, Nakamura K, Kishimoto K, Hori M, Tsuchikawa D, Shinntani N, Hashimoto H, Baba A, Koide R, Shioda S. Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse. Journal of Molecular Neuroscience : Mn. 43: 22-9. PMID 20703829 DOI: 10.1007/S12031-010-9434-X  0.515
2011 Sakurai Y, Shintani N, Hayata A, Hashimoto H, Baba A. Trophic effects of PACAP on pancreatic islets: a mini-review. Journal of Molecular Neuroscience : Mn. 43: 3-7. PMID 20645023 DOI: 10.1007/S12031-010-9424-Z  0.438
2011 Sakurai Y, Shintani N, Arimori A, Hamagami K, Higuchi N, Inoue H, Ikeda K, Hayata A, Hashimoto H, Baba A. Cerulein-induced acute pancreatitis in PACAP knockout mice. Journal of Molecular Neuroscience : Mn. 43: 8-15. PMID 20567937 DOI: 10.1007/S12031-010-9396-Z  0.536
2010 Sándor K, Kormos V, Botz B, Imreh A, Bölcskei K, Gaszner B, Markovics A, Szolcsányi J, Shintani N, Hashimoto H, Baba A, Reglodi D, Helyes Z. Impaired nocifensive behaviours and mechanical hyperalgesia, but enhanced thermal allodynia in pituitary adenylate cyclase-activating polypeptide deficient mice. Neuropeptides. 44: 363-71. PMID 20621353 DOI: 10.1016/J.Npep.2010.06.004  0.526
2010 Purwana IN, Kanasaki H, Oride A, Mijiddorj T, Shintani N, Hashimoto H, Baba A, Miyazaki K. GnRH-induced PACAP and PAC1 receptor expression in pituitary gonadotrophs: a possible role in the regulation of gonadotropin subunit gene expression. Peptides. 31: 1748-55. PMID 20553777 DOI: 10.1016/J.Peptides.2010.05.012  0.488
2010 Nakata M, Shintani N, Hashimoto H, Baba A, Yada T. Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity. Journal of Molecular Neuroscience : Mn. 42: 404-10. PMID 20461496 DOI: 10.1007/S12031-010-9383-4  0.495
2010 Hatanaka M, Shibata N, Shintani N, Haba R, Hayata A, Hashimoto H, Baba A. 15d-prostaglandin J2 enhancement of nerve growth factor-induced neurite outgrowth is blocked by the chemoattractant receptor- homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist CAY10471 in PC12 cells. Journal of Pharmacological Sciences. 113: 89-93. PMID 20424389 DOI: 10.1254/Jphs.10001Sc  0.48
2010 Kemény A, Reglodi D, Cseharovszky R, Hashimoto H, Baba A, Szolcsányi J, Pintér E, Helyes Z. Pituitary adenylate cyclase-activating polypeptide deficiency enhances oxazolone-induced allergic contact dermatitis in mice. Journal of Molecular Neuroscience : Mn. 42: 443-9. PMID 20414744 DOI: 10.1007/S12031-010-9368-3  0.532
2010 Ohtaki H, Satoh A, Nakamachi T, Yofu S, Dohi K, Mori H, Ohara K, Miyamoto K, Hashimoto H, Shintani N, Baba A, Matsunaga M, Shioda S. Regulation of oxidative stress by pituitary adenylate cyclase-activating polypeptide (PACAP) mediated by PACAP receptor. Journal of Molecular Neuroscience : Mn. 42: 397-403. PMID 20387010 DOI: 10.1007/S12031-010-9350-0  0.495
2010 Ferencz A, Weber G, Helyes Z, Hashimoto H, Baba A, Reglodi D. Presence of endogenous PACAP-38 ameliorated intestinal cold preservation tissue injury. Journal of Molecular Neuroscience : Mn. 42: 428-34. PMID 20379803 DOI: 10.1007/S12031-010-9352-Y  0.482
2010 Mori H, Nakamachi T, Ohtaki H, Yofu S, Sato A, Endo K, Iso Y, Suzuki H, Takeyama Y, Shintani N, Hashimoto H, Baba A, Shioda S. Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on Doxorubicin-induced cardiomyopathy in mice. Circulation Journal : Official Journal of the Japanese Circulation Society. 74: 1183-90. PMID 20378996 DOI: 10.1253/Circj.Cj-09-1024  0.558
2010 Kawaguchi C, Isojima Y, Shintani N, Hatanaka M, Guo X, Okumura N, Nagai K, Hashimoto H, Baba A. PACAP-deficient mice exhibit light parameter-dependent abnormalities on nonvisual photoreception and early activity onset. Plos One. 5: e9286. PMID 20174586 DOI: 10.1371/Journal.Pone.0009286  0.54
2010 Tanida M, Shintani N, Morita Y, Tsukiyama N, Hatanaka M, Hashimoto H, Sawai H, Baba A, Nagai K. Regulation of autonomic nerve activities by central pituitary adenylate cyclase-activating polypeptide. Regulatory Peptides. 161: 73-80. PMID 20171991 DOI: 10.1016/J.Regpep.2010.02.002  0.47
2010 Ishihama T, Ago Y, Shintani N, Hashimoto H, Baba A, Takuma K, Matsuda T. Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice. Behavioural Brain Research. 209: 274-80. PMID 20144662 DOI: 10.1016/J.Bbr.2010.02.009  0.522
2010 Yamada K, Matsuzaki S, Hattori T, Kuwahara R, Taniguchi M, Hashimoto H, Shintani N, Baba A, Kumamoto N, Yamada K, Yoshikawa T, Katayama T, Tohyama M. Increased stathmin1 expression in the dentate gyrus of mice causes abnormal axonal arborizations. Plos One. 5: e8596. PMID 20062533 DOI: 10.1371/journal.pone.0008596  0.549
2010 Tanaka K, Kunishige-Yamamoto A, Hashimoto H, Shintani N, Hayata A, Baba A. Increased ethanol preference and serotonin 1A receptor-dependent attenuation of ethanol-induced hypothermia in PACAP-deficient mice. Biochemical and Biophysical Research Communications. 391: 773-7. PMID 19944672 DOI: 10.1016/J.Bbrc.2009.11.136  0.502
2010 Horvath G, Mark L, Brubel R, Szakaly P, Racz B, Kiss P, Tamas A, Helyes Z, Lubics A, Hashimoto H, Baba A, Shintani N, Furjes G, Nemeth J, Reglodi D. Mice deficient in pituitary adenylate cyclase activating polypeptide display increased sensitivity to renal oxidative stress in vitro. Neuroscience Letters. 469: 70-4. PMID 19932736 DOI: 10.1016/J.Neulet.2009.11.046  0.517
2010 Hashimoto R, Hashimoto H, Shintani N, Ohi K, Hori H, Saitoh O, Kosuga A, Tatsumi M, Iwata N, Ozaki N, Kamijima K, Baba A, Takeda M, Kunugi H. Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder. Neuroscience Letters. 468: 300-2. PMID 19914336 DOI: 10.1016/J.Neulet.2009.11.019  0.469
2010 Nakamachi T, Ohtaki H, Yofu S, Dohi K, Watanabe J, Mori H, Sato A, Hashimoto H, Shintani N, Baba A, Shioda S. Endogenous pituitary adenylate cyclase activating polypeptide is involved in suppression of edema in the ischemic brain. Acta Neurochirurgica. Supplement. 106: 43-6. PMID 19812918 DOI: 10.1007/978-3-211-98811-4_6  0.5
2010 Ago Y, Yoneyama M, Ogita K, Shintani N, Hashimoto H, Baba A, Takuma K, Matsuda T. P3-e15Roles of neuropeptide PACAP in enriched environment-induced neurogenesis and neurotrophic/growth factor expression in the hippocampus Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.1628  0.44
2010 Hazama K, Hayata A, Uetsuki K, Ogata K, Taziri M, Momosaki H, Shintani N, Hashimoto H, Baba A. Interaction between genetic and non-genetic factors modulates psychomotor behaviors in PACAP-heterozygous knockout mice Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.130  0.472
2010 Haba R, Shintani N, Wang H, Onaka Y, Hayata A, Hashimoto H, Hirai H, Nagata K, Nakamura M, Baba A. Involvement of a prostanoid receptor CRTH2 in the LPS-induced decrease in object exploration behavior Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.122  0.453
2009 Vaudry D, Falluel-Morel A, Bourgault S, Basille M, Burel D, Wurtz O, Fournier A, Chow BK, Hashimoto H, Galas L, Vaudry H. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacological Reviews. 61: 283-357. PMID 19805477 DOI: 10.1124/Pr.109.001370  0.341
2009 Hamagami K, Sakurai Y, Shintani N, Higuchi N, Ikeda K, Hashimoto H, Suzuki A, Kiyama H, Baba A. Over-expression of pancreatic pituitary adenylate cyclase-activating polypeptide (PACAP) aggravates cerulein-induced acute pancreatitis in mice. Journal of Pharmacological Sciences. 110: 451-8. PMID 19672038 DOI: 10.1254/Jphs.09119Fp  0.523
2009 Hashimoto H, Hashimoto R, Shintani N, Tanaka K, Yamamoto A, Hatanaka M, Guo X, Morita Y, Tanida M, Nagai K, Takeda M, Baba A. Depression-like behavior in the forced swimming test in PACAP-deficient mice: amelioration by the atypical antipsychotic risperidone. Journal of Neurochemistry. 110: 595-602. PMID 19457081 DOI: 10.1111/J.1471-4159.2009.06168.X  0.526
2009 Tsuchida R, Kubo M, Shintani N, Abe M, Köves K, Uetsuki K, Kuroda M, Hashimoto H, Baba A. Inhibitory effects of osemozotan, a serotonin 1A-receptor agonist, on methamphetamine-induced c-Fos expression in prefrontal cortical neurons. Biological & Pharmaceutical Bulletin. 32: 728-31. PMID 19336914 DOI: 10.1248/Bpb.32.728  0.501
2009 Tsuchida R, Kubo M, Kuroda M, Shibasaki Y, Shintani N, Abe M, Köves K, Hashimoto H, Baba A. An antihyperkinetic action by the serotonin 1A-receptor agonist osemozotan co-administered with psychostimulants or the non-stimulant atomoxetine in mice. Journal of Pharmacological Sciences. 109: 396-402. PMID 19270432 DOI: 10.1254/Jphs.08297Fp  0.489
2009 Takamura H, Hashimoto R, Shintani N, Haba R, Yasuda Y, Ohi K, Fukumoto M, Yamamori H, Hashimoto H, Baba A, Takeda M. Behavioral analysis of transgenic mouse overexpressing dysbindin-1, a susceptibility gene for schizophrenia Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.579  0.447
2008 Hatanaka M, Tanida M, Shintani N, Isojima Y, Kawaguchi C, Hashimoto H, Kakuda M, Haba R, Nagai K, Baba A. Lack of light-induced elevation of renal sympathetic nerve activity and plasma corticosterone levels in PACAP-deficient mice. Neuroscience Letters. 444: 153-6. PMID 18722505 DOI: 10.1016/J.Neulet.2008.08.030  0.523
2008 Hagi K, Azuma YT, Nakajima H, Shintani N, Hashimoto H, Baba A, Takeuchi T. Involvements of PHI-nitric oxide and PACAP-BK channel in the sustained relaxation of mouse gastric fundus. European Journal of Pharmacology. 590: 80-6. PMID 18602629 DOI: 10.1016/J.Ejphar.2008.05.045  0.443
2008 Kasai A, Shintani N, Kato H, Matsuda S, Gomi F, Haba R, Hashimoto H, Kakuda M, Tano Y, Baba A. Retardation of retinal vascular development in apelin-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1717-22. PMID 18599802 DOI: 10.1161/Atvbaha.108.163402  0.512
2008 Tomimoto S, Ojika T, Shintani N, Hashimoto H, Hamagami K, Ikeda K, Nakata M, Yada T, Sakurai Y, Shimada T, Morita Y, Ishida C, Baba A. Markedly reduced white adipose tissue and increased insulin sensitivity in adcyap1-deficient mice. Journal of Pharmacological Sciences. 107: 41-8. PMID 18446003 DOI: 10.1254/Jphs.Fp0072173  0.485
2008 Heinzlmann A, Kirilly E, Meltzer K, Szabó E, Baba A, Hashimoto H, Köves K. PACAP is transiently expressed in anterior pituitary gland of rats: in situ hybridization and cell immunoblot assay studies. Peptides. 29: 571-7. PMID 18243417 DOI: 10.1016/J.Peptides.2007.12.009  0.457
2008 Azuma YT, Hagi K, Shintani N, Kuwamura M, Nakajima H, Hashimoto H, Baba A, Takeuchi T. PACAP provides colonic protection against dextran sodium sulfate induced colitis. Journal of Cellular Physiology. 216: 111-9. PMID 18205183 DOI: 10.1002/Jcp.21381  0.52
2008 Koda K, Ago Y, Kawasaki T, Hashimoto H, Baba A, Matsuda T. Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice. Psychopharmacology. 196: 293-301. PMID 17912499 DOI: 10.1007/S00213-007-0962-1  0.489
2007 Fujii H, Ishihama T, Ago Y, Shintani N, Kakuda M, Hashimoto H, Baba A, Matsuda T. Methamphetamine-induced hyperactivity and behavioral sensitization in PACAP deficient mice. Peptides. 28: 1674-9. PMID 17658665 DOI: 10.1016/J.Peptides.2007.06.012  0.555
2007 Ago Y, Nakamura S, Kajita N, Uda M, Hashimoto H, Baba A, Matsuda T. Ritanserin reverses repeated methamphetamine-induced behavioral and neurochemical sensitization in mice. Synapse (New York, N.Y.). 61: 757-63. PMID 17568413 DOI: 10.1002/Syn.20421  0.501
2007 Ago Y, Takahashi K, Nakamura S, Hashimoto H, Baba A, Matsuda T. Anxiety-like and exploratory behaviors of isolation-reared mice in the staircase test. Journal of Pharmacological Sciences. 104: 153-8. PMID 17538228 DOI: 10.1254/Jphs.Fp0070325  0.52
2007 Hashimoto H, Shintani N, Baba A. [Neuropeptide PACAP and neuropsychological function: unexpected insights from mouse mutants]. Seikagaku. the Journal of Japanese Biochemical Society. 79: 375-9. PMID 17511259  0.376
2007 Hattori T, Baba K, Matsuzaki S, Honda A, Miyoshi K, Inoue K, Taniguchi M, Hashimoto H, Shintani N, Baba A, Shimizu S, Yukioka F, Kumamoto N, Yamaguchi A, Tohyama M, et al. A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth. Molecular Psychiatry. 12: 398-407. PMID 17389905 DOI: 10.1038/Sj.Mp.4001945  0.484
2007 Hashimoto R, Hashimoto H, Shintani N, Chiba S, Hattori S, Okada T, Nakajima M, Tanaka K, Kawagishi N, Nemoto K, Mori T, Ohnishi T, Noguchi H, Hori H, Suzuki T, et al. Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia. Molecular Psychiatry. 12: 1026-32. PMID 17387318 DOI: 10.1038/Sj.Mp.4001982  0.458
2007 Shintani N, Ogita K, Hashimoto H, Baba A. Recent studies on the trimethyltin actions in central nervous systems. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 127: 451-61. PMID 17329931 DOI: 10.1248/Yakushi.127.451  0.518
2007 Isojima Y, Kawaguchi C, Shintani N, Hatanaka M, Guo X, Nagai K, Hashimoto H, Baba A. P2-g35PACAP deficient mice exhibit light parameter dependent abnormalities of nonvisual photoreception Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.707  0.492
2007 Yamada K, Matsuzaki S, Hattori T, Hashimoto H, Shintani N, Baba A, Tohyama M. Function analysis of pituitary adenylate cyclase-activating polypeptide associated with schizophrenia in hippocampal dentate gyrus Neuroscience Research. 58: S221. DOI: 10.1016/J.Neures.2007.06.470  0.428
2006 Nakamura S, Ago Y, Hayashi A, Itoh S, Kakuda M, Hashimoto H, Baba A, Matsuda T. Modification of cocaine-induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice. Synapse (New York, N.Y.). 60: 479-84. PMID 16952156 DOI: 10.1002/Syn.20323  0.469
2006 Shintani N, Hashimoto H, Tanaka K, Kawagishi N, Kawaguchi C, Hatanaka M, Ago Y, Matsuda T, Baba A. Serotonergic inhibition of intense jumping behavior in mice lacking PACAP (Adcyap1-/-). Annals of the New York Academy of Sciences. 1070: 545-9. PMID 16888223 DOI: 10.1196/Annals.1317.079  0.541
2006 Morita Y, Yanagida D, Shintani N, Ogita K, Nishiyama N, Tsuchida R, Hashimoto H, Baba A. Lack of trimethyltin (TMT)-induced elevation of plasma corticosterone in PACAP-deficient mice. Annals of the New York Academy of Sciences. 1070: 450-6. PMID 16888208 DOI: 10.1196/Annals.1317.060  0.559
2006 Hirose M, Hashimoto H, Iga J, Shintani N, Nakanishi M, Arakawa N, Shimada T, Baba A. Inhibition of self-renewal and induction of neural differentiation by PACAP in neural progenitor cells. Annals of the New York Academy of Sciences. 1070: 342-7. PMID 16888189 DOI: 10.1196/Annals.1317.042  0.582
2006 Hashimoto H, Shintani N, Baba A. New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice. Annals of the New York Academy of Sciences. 1070: 75-89. PMID 16888150 DOI: 10.1196/Annals.1317.038  0.527
2006 Tanaka K, Shintani N, Hashimoto H, Kawagishi N, Ago Y, Matsuda T, Hashimoto R, Kunugi H, Yamamoto A, Kawaguchi C, Shimada T, Baba A. Psychostimulant-induced attenuation of hyperactivity and prepulse inhibition deficits in Adcyap1-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5091-7. PMID 16687500 DOI: 10.1523/Jneurosci.4376-05.2006  0.545
2006 Ohtaki H, Nakamachi T, Dohi K, Aizawa Y, Takaki A, Hodoyama K, Yofu S, Hashimoto H, Shintani N, Baba A, Kopf M, Iwakura Y, Matsuda K, Arimura A, Shioda S. Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6. Proceedings of the National Academy of Sciences of the United States of America. 103: 7488-93. PMID 16651528 DOI: 10.1073/Pnas.0600375103  0.495
2006 Toyoshima M, Takeuchi T, Goto H, Mukai K, Shintani N, Hashimoto H, Baba A, Hata F. Roles of PACAP and PHI as inhibitory neurotransmitters in the circular muscle of mouse antrum. PflüGers Archiv : European Journal of Physiology. 451: 559-68. PMID 16292577 DOI: 10.1007/S00424-005-1491-6  0.541
2006 Mukai K, Takeuchi T, Toyoshima M, Satoh Y, Fujita A, Shintani N, Hashimoto H, Baba A, Hata F. PACAP- and PHI-mediated sustained relaxation in circular muscle of gastric fundus: findings obtained in PACAP knockout mice. Regulatory Peptides. 133: 54-61. PMID 16229904 DOI: 10.1016/J.Regpep.2005.09.019  0.533
2006 Nakamachi T, Ohtaki H, Dohi K, Hodoyama K, Yofu S, Hashimoto H, Shintani N, Baba A, Arimura A, Shioda S. Endogenous PACAP acts as a neuroprotectant against ischemic neuronal damage mediating bcl-2 signal Frontiers in Neuroendocrinology. 27: 112. DOI: 10.1016/J.Yfrne.2006.03.291  0.429
2005 Shintani N, Suetake S, Hashimoto H, Koga K, Kasai A, Kawaguchi C, Morita Y, Hirose M, Sakai Y, Tomimoto S, Matsuda T, Baba A. Neuroprotective action of endogenous PACAP in cultured rat cortical neurons. Regulatory Peptides. 126: 123-8. PMID 15620425 DOI: 10.1016/J.Regpep.2004.08.014  0.615
2005 Hirose M, Hashimoto H, Shintani N, Nakanishi M, Arakawa N, Iga J, Niwa H, Miyazaki J, Baba A. Differential expression of mRNAs for PACAP and its receptors during neural differentiation of embryonic stem cells. Regulatory Peptides. 126: 109-13. PMID 15620423 DOI: 10.1016/J.Regpep.2004.08.018  0.606
2005 Ogawa T, Nakamachi T, Ohtaki H, Hashimoto H, N S, Baba A, Watanabe J, Kikuyama S, Shioda S. Monoaminergic neuronal development is not affected in PACAP-gene-deficient mice. Regulatory Peptides. 126: 103-8. PMID 15620422 DOI: 10.1016/J.Regpep.2004.08.034  0.536
2004 Kasai A, Shintani N, Oda M, Kakuda M, Hashimoto H, Matsuda T, Hinuma S, Baba A. Apelin is a novel angiogenic factor in retinal endothelial cells. Biochemical and Biophysical Research Communications. 325: 395-400. PMID 15530405 DOI: 10.1016/J.Bbrc.2004.10.042  0.442
2004 Shintani N, Hashimoto H, Tanaka K, Kawaguchi C, Tomimoto S, Baba A. Overexpression of PACAP in the pancreas failed to rescue early postnatal mortality in PACAP-null mice. Regulatory Peptides. 123: 155-9. PMID 15518906 DOI: 10.1016/J.Regpep.2004.04.022  0.52
2004 Tanaka K, Hashimoto H, Shintani N, Yamamoto A, Baba A. Reduced hypothermic and hypnotic responses to ethanol in PACAP-deficient mice. Regulatory Peptides. 123: 95-8. PMID 15518898 DOI: 10.1016/J.Regpep.2004.05.017  0.495
2004 Nakata M, Kohno D, Shintani N, Nemoto Y, Hashimoto H, Baba A, Yada T. PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus. Neuroscience Letters. 370: 252-6. PMID 15488333 DOI: 10.1016/J.Neulet.2004.08.034  0.507
2004 Mabuchi T, Shintani N, Matsumura S, Okuda-Ashitaka E, Hashimoto H, Muratani T, Minami T, Baba A, Ito S. Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7283-91. PMID 15317855 DOI: 10.1523/Jneurosci.0983-04.2004  0.505
2004 Freson K, Hashimoto H, Thys C, Wittevrongel C, Danloy S, Morita Y, Shintani N, Tomiyama Y, Vermylen J, Hoylaerts MF, Baba A, Van Geet C. The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation. The Journal of Clinical Investigation. 113: 905-12. PMID 15067323 DOI: 10.1172/Jci19252  0.483
2004 Shintani N, Hashimoto H, Baba A. [Altered higher brain function in PACAP-knockout mice]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 123: 274-80. PMID 15056943 DOI: 10.1254/Fpj.123.274  0.543
2004 Tomimoto S, Hashimoto H, Shintani N, Baba A. [Transgenic mice overexpressing PACAP in pancreatic beta-cells: acute and chronic effects on insulin and glucose homeostasis]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 123: 261-6. PMID 15056941 DOI: 10.1254/Fpj.123.261  0.489
2004 Sakai Y, Hashimoto H, Shintani N, Katoh H, Negishi M, Kawaguchi C, Kasai A, Baba A. PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells. Brain Research. Molecular Brain Research. 123: 18-26. PMID 15046862 DOI: 10.1016/J.Molbrainres.2003.12.013  0.462
2004 Tomimoto S, Hashimoto H, Shintani N, Yamamoto K, Kawabata Y, Hamagami K, Yamagata K, Miyagawa J, Baba A. Overexpression of pituitary adenylate cyclase-activating polypeptide in islets inhibits hyperinsulinemia and islet hyperplasia in agouti yellow mice. The Journal of Pharmacology and Experimental Therapeutics. 309: 796-803. PMID 14742740 DOI: 10.1124/Jpet.103.062919  0.531
2003 Shintani N, Tanaka K, Hashimoto H, Baba A. [Altered behavioral response to centrally acting drugs in mice lacking PACAP]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 122: 1P-4P. PMID 14727506  0.45
2003 Vereczki V, Köves K, Tóth ZE, Baba A, Hashimoto H, Fógel K, Arimura A, Kausz M. Pituitary adenylate cyclase-activating polypeptide does not colocalize with vasoactive intestinal polypeptide in the hypothalamic magnocellular nuclei and posterior pituitary of cats and rats. Endocrine. 22: 225-37. PMID 14709795 DOI: 10.1385/Endo:22:3:225  0.444
2003 Shintani N, Tomimoto S, Hashimoto H, Kawaguchi C, Baba A. Functional roles of the neuropeptide PACAP in brain and pancreas. Life Sciences. 74: 337-43. PMID 14607262 DOI: 10.1016/J.Lfs.2003.09.021  0.538
2003 Matsuyama S, Matsumoto A, Hashimoto H, Shintani N, Baba A. Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP) or PACAP type 1 receptor-mutant mice. Neuroreport. 14: 2095-8. PMID 14600504 DOI: 10.1097/00001756-200311140-00017  0.543
2003 Hashimoto H, Kunugi A, Arakawa N, Shintani N, Fujita T, Kasai A, Kawaguchi C, Morita Y, Hirose M, Sakai Y, Baba A. Possible involvement of a cyclic AMP-dependent mechanism in PACAP-induced proliferation and ERK activation in astrocytes. Biochemical and Biophysical Research Communications. 311: 337-43. PMID 14592419 DOI: 10.1016/J.Bbrc.2003.10.005  0.587
2003 Hashimoto H, Shintani N. [In vivo functional analysis of the neuropeptide PACAP using gene-targeted mice]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 122: 427-35. PMID 14569162 DOI: 10.1254/Fpj.122.427  0.407
2003 Kawaguchi C, Tanaka K, Isojima Y, Shintani N, Hashimoto H, Baba A, Nagai K. Changes in light-induced phase shift of circadian rhythm in mice lacking PACAP. Biochemical and Biophysical Research Communications. 310: 169-75. PMID 14511666 DOI: 10.1016/J.Bbrc.2003.09.004  0.477
2003 Yamamoto K, Hashimoto H, Tomimoto S, Shintani N, Miyazaki J, Tashiro F, Aihara H, Nammo T, Li M, Yamagata K, Miyagawa J, Matsuzawa Y, Kawabata Y, Fukuyama Y, Koga K, et al. Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes. Diabetes. 52: 1155-62. PMID 12716746 DOI: 10.2337/Diabetes.52.5.1155  0.514
2002 Sakai Y, Hashimoto H, Shintani N, Ichibori A, Tomimoto S, Tanaka K, Hirose M, Baba A. Involvement of intracellular Ca2+ elevation but not cyclic AMP in PACAP-induced p38 MAP kinase activation in PC12 cells. Regulatory Peptides. 109: 149-53. PMID 12409227 DOI: 10.1016/S0167-0115(02)00198-2  0.582
2002 Shintani N, Mori W, Hashimoto H, Imai M, Tanaka K, Tomimoto S, Hirose M, Kawaguchi C, Baba A. Defects in reproductive functions in PACAP-deficient female mice. Regulatory Peptides. 109: 45-8. PMID 12409213 DOI: 10.1016/S0167-0115(02)00169-6  0.585
2002 Mukai K, Satoh Y, Fujita A, Takeuchi T, Shintani N, Hashimoto H, Baba A, Hata F. PAC1 receptor-mediated relaxation of longitudinal muscle of the mouse proximal colon. Japanese Journal of Pharmacology. 90: 97-100. PMID 12396034 DOI: 10.1254/Jjp.90.97  0.547
2002 Hashimoto H, Shintani N, Baba A. Higher brain functions of PACAP and a homologous Drosophila memory gene amnesiac: insights from knockouts and mutants Biochemical and Biophysical Research Communications. 297: 427-432. PMID 12270109 DOI: 10.1016/S0006-291X(02)02144-7  0.505
2002 Hashimoto H, Shintani N, Nishino A, Okabe M, Ikawa M, Matsuyama S, Itoh K, Yamamoto K, Tomimoto S, Fujita T, Hagihara N, Mori W, Koyama Y, Matsuda T, Nagata S, et al. Mice with markedly reduced PACAP (PAC1) receptor expression by targeted deletion of the signal peptide Journal of Neurochemistry. 75: 1810-1817. PMID 11032869 DOI: 10.1046/J.1471-4159.2000.0751810.X  0.526
2002 Hosoi R, Matsuda T, Asano S, Nakamura H, Hashimoto H, Takuma K, Baba A. Isoform‐Specific Up‐Regulation by Ouabain of Na+,K+‐ATPase in Cultured Rat Astrocytes Journal of Neurochemistry. 69: 2189-2196. PMID 9349566 DOI: 10.1046/J.1471-4159.1997.69052189.X  0.417
2002 Takuma K, Matsuda T, Hashimoto H, Kitanaka J, Asano S, Kishida Y, Baba A. Role of Na(+)-Ca2+ exchanger in agonist-induced Ca2+ signaling in cultured rat astrocytes. Journal of Neurochemistry. 67: 1840-1845. PMID 8863488 DOI: 10.1046/J.1471-4159.1996.67051840.X  0.428
2001 Hashimoto H, Shintani N, Tanaka K, Mori W, Hirose M, Matsuda T, Sakaue M, Miyazaki J, Niwa H, Tashiro F, Yamamoto K, Koga K, Tomimoto S, Kunugi A, Suetake S, et al. Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Proceedings of the National Academy of Sciences of the United States of America. 98: 13355-60. PMID 11687615 DOI: 10.1073/Pnas.231094498  0.652
2001 Sakai Y, Hashimoto H, Shintani N, Tomimoto S, Tanaka K, Ichibori A, Hirose M, Baba A. Involvement of p38 MAP kinase pathway in the synergistic activation of PACAP mRNA expression by NGF and PACAP in PC12h cells. Biochemical and Biophysical Research Communications. 285: 656-61. PMID 11453643 DOI: 10.1006/Bbrc.2001.5244  0.591
2001 Hashimoto H, Hagihara N, Koga K, Yamamoto K, Shintani N, Tomimoto S, Mori W, Koyama Y, Matsuda T, Baba A. Synergistic induction of pituitary adenylate cyclase-activating polypeptide (PACAP) gene expression by nerve growth factor and PACAP in PC12 cells. Journal of Neurochemistry. 74: 501-507. PMID 10646500 DOI: 10.1046/J.1471-4159.2000.740501.X  0.492
2001 Koyama Y, Mizobata T, Yamamoto N, Hashimoto H, Matsuda T, Baba A. Endothelins stimulate expression of cyclooxygenase 2 in rat cultured astrocytes. Journal of Neurochemistry. 73: 1004-1011. PMID 10461889 DOI: 10.1046/J.1471-4159.1999.0731004.X  0.446
2000 Shintani N, Hashimoto H, Kunugi A, Koyama Y, Yamamoto K, Tomimoto S, Mori W, Matsuda T, Baba A. Desensitization, surface expression, and glycosylation of a functional, epitope-tagged type I PACAP (PAC1) receptor Biochimica Et Biophysica Acta. 1509: 195-202. PMID 11118531 DOI: 10.1016/S0005-2736(00)00295-9  0.486
2000 Arakawa N, Sakaue M, Yokoyama I, Hashimoto H, Koyama Y, Baba A, Matsuda T. KB-R7943 Inhibits Store-Operated Ca2+ Entry in Cultured Neurons and Astrocytes Biochemical and Biophysical Research Communications. 279: 354-357. PMID 11118291 DOI: 10.1006/Bbrc.2000.3968  0.441
2000 Koyama Y, Yoshioka Y, Hashimoto H, Matsuda T, Baba A. Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components. Neuroscience. 101: 219-227. PMID 11068150 DOI: 10.1016/S0306-4522(00)00330-4  0.446
2000 Sakaue M, Nakamura H, Kaneko I, Kawasaki Y, Arakawa N, Hashimoto H, Koyama Y, Baba A, Matsuda T. Na+–Ca2+ exchanger isoforms in rat neuronal preparations: different changes in their expression during postnatal development Brain Research. 881: 212-216. PMID 11036162 DOI: 10.1016/S0006-8993(00)02808-0  0.458
2000 Koyama Y, Kimura Y, Yoshioka Y, Wakamatsu D, Kozaki R, Hashimoto H, Matsuda T, Baba A. Serum-deprivation induces cell death of rat cultured microglia accompanied with expression of Bax protein. Japanese Journal of Pharmacology. 83: 351-354. PMID 11001183 DOI: 10.1254/Jjp.83.351  0.443
2000 Sakaue M, Somboonthum P, Nishihara B, Koyama Y, Hashimoto H, Baba A, Matsuda T. Postsynaptic 5-hydroxytryptamine1A receptor activation increases in vivo dopamine release in rat prefrontal cortex British Journal of Pharmacology. 129: 1028-1034. PMID 10696105 DOI: 10.1038/Sj.Bjp.0703139  0.453
2000 Koyama Y, Kimura Y, Hashimoto H, Matsuda T, Baba A. L-lactate inhibits L-cystine/L-glutamate exchange transport and decreases glutathione content in rat cultured astrocytes. Journal of Neuroscience Research. 59: 685-691. PMID 10686597 DOI: 10.1002/(Sici)1097-4547(20000301)59:5<685::Aid-Jnr12>3.0.Co;2-Z  0.418
2000 Koyama Y, Ishibashi T, Okamoto T, Matsuda T, Hashimoto H, Baba A. Transient treatments with l-glutamate and threo-β-hydroxyaspartate induce swelling of rat cultured astrocytes Neurochemistry International. 36: 167-173. PMID 10676881 DOI: 10.1016/S0197-0186(99)00109-6  0.423
2000 Hashimoto H, Shintani N, Matsuda T, Baba A. Generation and pharmacological analysis of PAC1 receptor and PACAP knockout mice Folia Pharmacologica Japonica. 116: 116-120. DOI: 10.1254/Fpj.116.Supplement_116  0.54
1999 Hashimoto H, Nishino A, Shintani N, Hagihara N, Copeland NG, Jenkins NA, Yamamoto K, Matsuda T, Ishihara T, Nagata S, Baba A. Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor. Genomics. 58: 90-3. PMID 10331949 DOI: 10.1006/Geno.1999.5805  0.441
1998 Yamamoto K, Hashimoto H, Hagihara N, Nishino A, Fujita T, Matsuda T, Baba A. Cloning And Characterization Of The Mouse Pituitary Adenylate Cyclase-Activating Polypeptide (Pacap) Gene Gene. 211: 63-69. PMID 9573339 DOI: 10.1016/S0378-1119(98)00110-3  0.445
1997 Nogi H, Hashimoto H, Fujita T, Hagihara N, Matsuda T, Baba A. Pituitary adenylate cyclase-activating polypeptide (PACAP) receptor mRNA in the rat adrenal gland: localization by in situ hybridization and identification of splice variants. Japanese Journal of Pharmacology. 75: 203-207. PMID 9414038 DOI: 10.1254/Jjp.75.203  0.473
1997 Hashimoto H, Ogawa N, Hagihara N, Yamamoto K, Imanishi K, Nogi H, Nishino A, Fujita T, Matsuda T, Nagata S, Baba A. Vasoactive Intestinal Polypeptide and Pituitary Adenylate Cyclase-Activating Polypeptide Receptor Chimeras Reveal Domains That Determine Specificity of Vasoactive Intestinal Polypeptide Binding and Activation Molecular Pharmacology. 52: 128-135. PMID 9224822 DOI: 10.1124/Mol.52.1.128  0.463
1997 Nogi H, Hashimoto H, Hagihara N, Shimada S, Yamamoto K, Matsuda T, Tohyama M, Baba A. Distribution of mRNAs for pituitary adenylate cyclase-activating polypeptide (PACAP), PACAP receptor, vasoactive intestinal polypeptide (VIP), and VIP receptors in the rat superior cervical ganglion. Neuroscience Letters. 227: 37-40. PMID 9178853 DOI: 10.1016/S0304-3940(97)00295-4  0.471
1997 Takahashi K, Hashimoto H, Baba A, Schaffer SW, Azuma J. Effect of taurine on angiotensin II-induced expression of immediate early response genes in primary cultured neonatal rat heart cells. Advances in Experimental Medicine and Biology. 403: 297-304. PMID 8915365 DOI: 10.1007/978-1-4899-0182-8_31  0.431
1996 Kitanaka J, Hashimoto H, Gotoh M, Kondo K, Sakata K, Hirasawa Y, Sawada M, Suzumura A, Marunouchi T, Matsuda T, Baba A. Expression pattern of messenger RNAs for prostanoid receptors in glial cell cultures. Brain Research. 707: 282-7. PMID 8919306 DOI: 10.1016/0006-8993(95)01256-7  0.508
1996 Hashimoto H, Nogi H, Mori K, Ohishi H, Shigemoto R, Yamamoto K, Matsuda T, Mizuno N, Nagata S, Baba A. Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study. The Journal of Comparative Neurology. 371: 567-77. PMID 8841910 DOI: 10.1002/(Sici)1096-9861(19960805)371:4<567::Aid-Cne6>3.0.Co;2-2  0.485
1996 Matsuda T, Takuma K, Nishiguchi E, Asano S, Hashimoto H, Azuma J, Baba A. Involvement of Na+-Ca2+ exchanger in reperfusion-induced delayed cell death of cultured rat astrocytes. European Journal of Neuroscience. 8: 951-958. PMID 8743743 DOI: 10.1111/J.1460-9568.1996.Tb01582.X  0.426
1996 Hashimoto H, Yamamoto K, Hagihara N, Ogawa N, Nishino A, Aino H, Nogi H, Imanishi K, Matsuda T, Baba A. cDNA cloning of a mouse pituitary avenylate cyclase-activating polypeptive receptor Biochimica Et Biophysica Acta. 1281: 129-133. PMID 8664310 DOI: 10.1016/0005-2736(96)00056-9  0.493
1995 Kitanakaa Ji, Hashimoto H, Sugimoto Y, Sawada M, Negishi M, Suzumura A, Marunouchi T, Ichikawa A, Baba A. cDNA cloning of a thromboxane A2 receptor from rat astrocytes. Biochimica Et Biophysica Acta. 1265: 220-223. PMID 7696353 DOI: 10.1016/0167-4889(94)00225-4  0.311
1995 Kondo K, Hashimoto H, Sakata K, Saga H, Kitanaka J, Baba A. Stimulation of cyclic AMP formation by pituitary adenylate cyclase-activating polypeptide is attenuated by glutamate in rat brain slices. Japanese Journal of Pharmacology. 67: 399-401. PMID 7650875 DOI: 10.1254/Jjp.67.399  0.493
1995 Aino H, Hashimoto H, Ogawa N, Nishino A, Yamamoto K, Nogi H, Nagata S, Baba A. Structure Of The Gene Encoding The Mouse Pituitary Adenylate Cyclase-Activating Polypeptide Receptor Gene. 164: 301-304. PMID 7590347 DOI: 10.1016/0378-1119(95)00391-I  0.45
1995 Watanabe D, Suda T, Hashimoto H, Nagata S. Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders. The Embo Journal. 14: 12-18. DOI: 10.1002/J.1460-2075.1995.Tb06970.X  0.38
1994 Hashimoto H, Aino H, Ogawa N, Nagata S, Baba A. Identification and Characterization of Parathyroid Hormone/Parathyroid Hormone-related Peptide Receptor in Cultured Astrocytes Biochemical and Biophysical Research Communications. 200: 1042-1048. PMID 8179580 DOI: 10.1006/Bbrc.1994.1555  0.478
1994 Takuma K, Matsuda T, Hashimoto H, Asano S, Baba A. Cultured rat astrocytes possess Na+-Ca2+ exchanger Glia. 12: 336-342. PMID 7890336 DOI: 10.1002/Glia.440120410  0.421
1993 Hashimoto H, Ishihara T, Shigemoto R, Mori K, Nagata S. Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide. Neuron. 11: 333-42. PMID 8394723 DOI: 10.1016/0896-6273(93)90188-W  0.332
1991 Negishi M, Hashimoto H, Yatsunami K, Kurozumi S, Ichikawa A. TEI-9063, a stable and highly specific prostacyclin analogue for the prostacyclin receptor in mastocytoma P-815 cells. Prostaglandins. 42: 225-237. PMID 1723528 DOI: 10.1016/0090-6980(91)90112-S  0.306
1990 Yatsunami K, Fujisawa J, Hashimoto H, Kimura K, Takahashi S, Ichikawa A. Effect of tunicamycin on functions of PGE1 receptors from mouse mastocytoma P-815 cells. Biochimica Et Biophysica Acta. 1051: 94-99. PMID 2153417 DOI: 10.1016/0167-4889(90)90178-G  0.303
1985 Nonomura M, Hoshino K, Harigaya T, Hashimoto H, Yoshida O. Effects of hyperprolactinaemia on reproduction in male mice Journal of Endocrinology. 107: 71-76. PMID 4045355 DOI: 10.1677/Joe.0.1070071  0.367
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