Year |
Citation |
Score |
2020 |
Brunet MA, Leblanc S, Roucou X. Reconsidering proteomic diversity with functional investigation of small ORFs and alternative ORFs. Experimental Cell Research. 112057. PMID 32387289 DOI: 10.1016/J.Yexcr.2020.112057 |
0.328 |
|
2020 |
Dubois ML, Meller A, Samandi S, Brunelle M, Frion J, Brunet MA, Toupin A, Beaudoin MC, Jacques JF, Lévesque D, Scott MS, Lavigne P, Roucou X, Boisvert FM. UBB pseudogene 4 encodes functional ubiquitin variants. Nature Communications. 11: 1306. PMID 32161257 DOI: 10.1038/S41467-020-15090-6 |
0.421 |
|
2019 |
Cardon T, Hervé F, Delcourt V, Roucou X, Salzet M, Franck J, Fournier I. Optimized Sample Preparation Workflow for Improved Identification of Ghost Proteins. Analytical Chemistry. PMID 31829555 DOI: 10.1021/Acs.Analchem.9B04188 |
0.355 |
|
2019 |
Brunet MA, Roucou X. Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames. Journal of Visualized Experiments : Jove. PMID 31033953 DOI: 10.3791/59589 |
0.369 |
|
2018 |
Brunet MA, Brunelle M, Lucier JF, Delcourt V, Levesque M, Grenier F, Samandi S, Leblanc S, Aguilar JD, Dufour P, Jacques JF, Fournier I, Ouangraoua A, Scott MS, Boisvert FM, ... Roucou X, et al. OpenProt: a more comprehensive guide to explore eukaryotic coding potential and proteomes. Nucleic Acids Research. PMID 30299502 DOI: 10.1093/Nar/Gky936 |
0.338 |
|
2018 |
Delcourt V, Brunelle M, Roy AV, Jacques JF, Salzet M, Fournier I, Roucou X. The protein coded by a short open reading frame, not by the annotated coding sequence is the main gene product of the dual-coding gene MIEF1. Molecular & Cellular Proteomics : McP. PMID 30181344 DOI: 10.1074/Mcp.Ra118.000593 |
0.363 |
|
2017 |
Delcourt V, Franck J, Quanico J, Gimeno JP, Wisztorski M, Raffo Romero A, Kobeissy F, Roucou X, Salzet M, Fournier I. Top-down microproteomics bridged to MALDI MS imaging reveals the molecular physiome of brain regions. Molecular & Cellular Proteomics : McP. PMID 29122912 DOI: 10.1074/Mcp.M116.065755 |
0.312 |
|
2017 |
Samandi S, Roy AV, Delcourt V, Lucier JF, Gagnon J, Beaudoin MC, Vanderperre B, Breton MA, Motard J, Jacques JF, Brunelle M, Gagnon-Arsenault I, Fournier I, Ouangraoua A, Hunting DJ, ... ... Roucou X, et al. Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins. Elife. 6. PMID 29083303 DOI: 10.7554/Elife.27860 |
0.413 |
|
2017 |
Delcourt V, Franck J, Leblanc E, Narducci F, Robin YM, Gimeno JP, Quanico J, Wisztorski M, Kobeissy F, Jacques JF, Roucou X, Salzet M, Fournier I. Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer. Ebiomedicine. PMID 28629911 DOI: 10.1016/J.Ebiom.2017.06.001 |
0.338 |
|
2017 |
Delcourt V, Staskevicius A, Salzet M, Fournier I, Roucou X. Small proteins encoded by unannotated ORFs are rising stars of the proteome, confirming shortcomings in genome annotations and current vision of an mRNA. Proteomics. PMID 28627015 DOI: 10.1002/Pmic.201700058 |
0.387 |
|
2017 |
Samandi S, Roy AV, Delcourt V, Lucier J, Gagnon J, Beaudoin MC, Vanderperre B, Breton M, Motard J, Jacques J, Brunelle M, Gagnon-Arsenault I, Fournier I, Ouangraoua A, Hunting DJ, ... ... Roucou X, et al. Author response: Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins Elife. DOI: 10.7554/Elife.27860.083 |
0.353 |
|
2016 |
Mouilleron H, Delcourt V, Roucou X. Death of a dogma: eukaryotic mRNAs can code for more than one protein. Nucleic Acids Research. 44: 14-23. PMID 26578573 DOI: 10.1093/Nar/Gkv1218 |
0.375 |
|
2015 |
Landry CR, Zhong X, Nielly-Thibault L, Roucou X. Found in translation: functions and evolution of a recently discovered alternative proteome. Current Opinion in Structural Biology. 32: 74-80. PMID 25795211 DOI: 10.1016/J.Sbi.2015.02.017 |
0.409 |
|
2014 |
Roucou X. Regulation of PrP(C) signaling and processing by dimerization. Frontiers in Cell and Developmental Biology. 2: 57. PMID 25364762 DOI: 10.3389/Fcell.2014.00057 |
0.444 |
|
2014 |
Shott RH, Appanah C, Grenier C, Tremblay G, Roucou X, Schang LM. Development of kinomic analyses to identify dysregulated signaling pathways in cells expressing cytoplasmic PrP. Virology Journal. 11: 175. PMID 25280966 DOI: 10.1186/1743-422X-11-175 |
0.333 |
|
2014 |
Béland M, Bédard M, Tremblay G, Lavigne P, Roucou X. Aβ induces its own prion protein N-terminal fragment (PrPN1)-mediated neutralization in amorphous aggregates. Neurobiology of Aging. 35: 1537-48. PMID 24602510 DOI: 10.1016/J.Neurobiolaging.2014.02.001 |
0.651 |
|
2014 |
Béland M, Roucou X. Taking advantage of physiological proteolytic processing of the prion protein for a therapeutic perspective in prion and Alzheimer diseases. Prion. 8: 106-10. PMID 24335160 DOI: 10.4161/Pri.27438 |
0.674 |
|
2013 |
Vanderperre B, Lucier JF, Bissonnette C, Motard J, Tremblay G, Vanderperre S, Wisztorski M, Salzet M, Boisvert FM, Roucou X. Direct detection of alternative open reading frames translation products in human significantly expands the proteome. Plos One. 8: e70698. PMID 23950983 DOI: 10.1371/Journal.Pone.0070698 |
0.396 |
|
2013 |
Forget KJ, Tremblay G, Roucou X. p53 Aggregates penetrate cells and induce the co-aggregation of intracellular p53. Plos One. 8: e69242. PMID 23844254 DOI: 10.1371/Journal.Pone.0069242 |
0.444 |
|
2013 |
Bergeron D, Lapointe C, Bissonnette C, Tremblay G, Motard J, Roucou X. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein. The Journal of Biological Chemistry. 288: 21824-35. PMID 23760502 DOI: 10.1074/Jbc.M113.472654 |
0.349 |
|
2013 |
Béland M, Roucou X. Homodimerization as a molecular switch between low and high efficiency PrP C cell surface delivery and neuroprotective activity. Prion. 7: 170-4. PMID 23357826 DOI: 10.4161/Pri.23583 |
0.683 |
|
2013 |
Roostaee A, Beaudoin S, Staskevicius A, Roucou X. Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization. Molecular Neurodegeneration. 8: 5. PMID 23339399 DOI: 10.1186/1750-1326-8-5 |
0.574 |
|
2012 |
Béland M, Motard J, Barbarin A, Roucou X. PrP(C) homodimerization stimulates the production of PrPC cleaved fragments PrPN1 and PrPC1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13255-63. PMID 22993441 DOI: 10.1523/Jneurosci.2236-12.2012 |
0.669 |
|
2012 |
Vanderperre B, Lucier JF, Roucou X. HAltORF: a database of predicted out-of-frame alternative open reading frames in human. Database : the Journal of Biological Databases and Curation. 2012: bas025. PMID 22613085 DOI: 10.1093/Database/Bas025 |
0.314 |
|
2012 |
Béland M, Roucou X. The prion protein unstructured N-terminal region is a broad-spectrum molecular sensor with diverse and contrasting potential functions. Journal of Neurochemistry. 120: 853-68. PMID 22145935 DOI: 10.1111/J.1471-4159.2011.07613.X |
0.662 |
|
2011 |
Vanderperre B, Staskevicius AB, Tremblay G, McCoy M, O'Neill MA, Cashman NR, Roucou X. An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2373-86. PMID 21478263 DOI: 10.1096/Fj.10-173815 |
0.437 |
|
2010 |
Roostaee AR, Roostaee MH, Roucou X. An update on prion biology and proteomics Current Proteomics. 7: 36-48. DOI: 10.2174/157016410790979644 |
0.387 |
|
2009 |
Roostaee A, Côté S, Roucou X. Aggregation and amyloid fibril formation induced by chemical dimerization of recombinant prion protein in physiological-like conditions. The Journal of Biological Chemistry. 284: 30907-16. PMID 19710507 DOI: 10.1074/Jbc.M109.057950 |
0.483 |
|
2009 |
Roucou X. Prion protein and RNA: a view from the cytoplasm. Frontiers in Bioscience (Landmark Edition). 14: 5157-64. PMID 19482610 DOI: 10.2741/3592 |
0.392 |
|
2009 |
Roucou X. Reconstitution of chromatoid body-like particles in cultured cells: a novel approach to elucidate the mechanism of assembly and function of the chromatoid body. Rna Biology. 6: 165-8. PMID 19229140 DOI: 10.4161/Rna.6.2.8049 |
0.329 |
|
2009 |
Beaudoin S, Vanderperre B, Grenier C, Tremblay I, Leduc F, Roucou X. A large ribonucleoprotein particle induced by cytoplasmic PrP shares striking similarities with the chromatoid body, an RNA granule predicted to function in posttranscriptional gene regulation. Biochimica Et Biophysica Acta. 1793: 335-45. PMID 19014979 DOI: 10.1016/J.Bbamcr.2008.10.009 |
0.576 |
|
2008 |
Beaudoin S, Goggin K, Bissonnette C, Grenier C, Roucou X. Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells. Bmc Cell Biology. 9: 59. PMID 18937858 DOI: 10.1186/1471-2121-9-59 |
0.613 |
|
2008 |
Goggin K, Beaudoin S, Grenier C, Brown AA, Roucou X. Prion protein aggresomes are poly(A)+ ribonucleoprotein complexes that induce a PKR-mediated deficient cell stress response. Biochimica Et Biophysica Acta. 1783: 479-91. PMID 18023289 DOI: 10.1016/J.Bbamcr.2007.10.008 |
0.611 |
|
2007 |
Goggin K, Bissonnette C, Grenier C, Volkov L, Roucou X. Aggregation of cellular prion protein is initiated by proximity-induced dimerization. Journal of Neurochemistry. 102: 1195-205. PMID 17663754 DOI: 10.1111/J.1471-4159.2007.04611.X |
0.501 |
|
2006 |
Goggin K, Roucou X. [The prion protein does not hesitate to produce aggregates]. MéDecine Sciences : M/S. 22: 1013-4. PMID 17156713 DOI: 10.1051/medsci/200622121013 |
0.327 |
|
2006 |
Bounhar Y, Mann KK, Roucou X, LeBlanc AC. Prion protein prevents Bax-mediated cell death in the absence of other Bcl-2 family members in Saccharomyces cerevisiae. Fems Yeast Research. 6: 1204-12. PMID 17156017 DOI: 10.1111/J.1567-1364.2006.00122.X |
0.402 |
|
2006 |
Grenier C, Bissonnette C, Volkov L, Roucou X. Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells. Journal of Neurochemistry. 97: 1456-66. PMID 16696854 DOI: 10.1111/J.1471-4159.2006.03837.X |
0.432 |
|
2005 |
Roucou X, Giannopoulos PN, Zhang Y, Jodoin J, Goodyer CG, LeBlanc A. Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells Cell Death and Differentiation. 12: 783-795. PMID 15846375 DOI: 10.1038/Sj.Cdd.4401629 |
0.413 |
|
2005 |
Roucou X, LeBlanc AC. Cellular prion protein neuroprotective function: implications in prion diseases. Journal of Molecular Medicine (Berlin, Germany). 83: 3-11. PMID 15645198 DOI: 10.1007/S00109-004-0605-5 |
0.445 |
|
2004 |
Roucou X, Gains M, LeBlanc AC. Neuroprotective functions of prion protein. Journal of Neuroscience Research. 75: 153-61. PMID 14705136 DOI: 10.1002/Jnr.10864 |
0.435 |
|
2003 |
Roucou X, Guo Q, Zhang Y, Goodyer CG, LeBlanc AC. Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons. The Journal of Biological Chemistry. 278: 40877-81. PMID 12917444 DOI: 10.1074/Jbc.M306177200 |
0.38 |
|
2003 |
LeBlanc AC, Roucou X. Toxicity and protection in prions. Science (New York, N.Y.). 301: 168-9; author reply . PMID 12855791 DOI: 10.1126/Science.301.5630.168 |
0.324 |
|
2002 |
Lim ML, Lum MG, Hansen TM, Roucou X, Nagley P. On the release of cytochrome c from mitochondria during cell death signaling. Journal of Biomedical Science. 9: 488-506. PMID 12372987 DOI: 10.1159/000064722 |
0.408 |
|
2002 |
Roucou X, Montessuit S, Antonsson B, Martinou JC. Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. The Biochemical Journal. 368: 915-21. PMID 12193163 DOI: 10.1042/Bj20020972 |
0.342 |
|
2002 |
Roucou X, Rostovtseva T, Montessuit S, Martinou JC, Antonsson B. Bid induces cytochrome c-impermeable Bax channels in liposomes. The Biochemical Journal. 363: 547-52. PMID 11964155 DOI: 10.1042/Bj3630547 |
0.339 |
|
2001 |
Papakonstantinou T, Myers MA, Jois J, Roucou X, Prescott M, Rowley MJ, Mackay IR. Expression of protein tyrosine phosphatase-like molecule ICA512/IA-2 induces growth arrest in yeast cells and transfected mammalian cell lines Journal of Autoimmunity. 17: 51-61. PMID 11488637 DOI: 10.1006/Jaut.2001.0516 |
0.354 |
|
2000 |
Boyle GM, Roucou X, Nagley P, Devenish RJ, Prescott M. Modulation at a distance of proton conductance through the Saccharomyces cerevisiae mitochondrial F1F0-ATP synthase by variants of the oligomycin sensitivity-conferring protein containing substitutions near the C-terminus Journal of Bioenergetics and Biomembranes. 32: 595-607. PMID 15254373 DOI: 10.1023/A:1005674628249 |
0.32 |
|
2000 |
Stephens AN, Roucou X, Artika IM, Devenish RJ, Nagley P. Topology and proximity relationships of yeast mitochondrial ATP synthase subunit 8 determined by unique introduced cysteine residues European Journal of Biochemistry. 267: 6443-6451. PMID 11029588 DOI: 10.1046/J.1432-1327.2000.01733.X |
0.307 |
|
2000 |
Roucou X, Prescott M, Devenish RJ, Nagley P. A cytochrome c-GFP fusion is not released from mitochondria into the cytoplasm upon expression of Bax in yeast cells Febs Letters. 471: 235-239. PMID 10767430 DOI: 10.1016/S0014-5793(00)01404-6 |
0.388 |
|
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