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Michael Aschner - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Pharmacology, Neuroscience Biology, Toxicology
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Year Citation  Score
2022 Martins AC, Gubert P, Li J, Ke T, Nicolai MM, Moura AV, Bornhorst J, Bowman AB, Aschner M. as a Model to Study Manganese-Induced Neurotoxicity. Biomolecules. 12. PMID 36291605 DOI: 10.3390/biom12101396  0.302
2020 Torres-Román AL, García-Hernández VM, Rangel-López E, Ruiz-García E, Meneses-García A, Santamaría A, Aschner M, Prospero-García O, Ortega-Gómez A. Oleamide Induces Cell Death in Glioblastoma RG2 Cells by a Cannabinoid Receptor-Independent Mechanism. Neurotoxicity Research. PMID 32930995 DOI: 10.1007/S12640-020-00280-3  0.305
2020 Ajsuvakova OP, Tinkov AA, Aschner M, Rocha JBT, Michalke B, Skalnaya MG, Skalny AV, Butnariu M, Dadar M, Sarac I, Aaseth J, Bjørklund G. Sulfhydryl groups as targets of mercury toxicity. Coordination Chemistry Reviews. 417. PMID 32905350 DOI: 10.1016/J.Ccr.2020.213343  0.324
2020 Pajarillo E, Johnson J, Rizor A, Nyarko-Danquah I, Adinew G, Bornhorst J, Stiboller M, Schwerdtle T, Son DS, Aschner M, Lee E. Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitigates manganese-induced dopaminergic neurotoxicity. The Journal of Biological Chemistry. PMID 32893191 DOI: 10.1074/Jbc.Ra120.015552  0.391
2020 Ijomone OM, Ijomone OK, Iroegbu JD, Ifenatuoha CW, Olung NF, Aschner M. Epigenetic influence of environmentally neurotoxic metals. Neurotoxicology. 81: 51-65. PMID 32882300 DOI: 10.1016/J.Neuro.2020.08.005  0.322
2020 Tang J, Zheng C, Zheng F, Li Y, Wang YL, Aschner M, Guo Z, Yu G, Wu S, Li H. Global N6-methyladenosine profiling of cobalt-exposed cortex and human neuroblastoma H4 cells presents epitranscriptomics alterations in neurodegenerative disease-associated genes. Environmental Pollution (Barking, Essex : 1987). 266: 115326. PMID 32827984 DOI: 10.1016/J.Envpol.2020.115326  0.375
2020 Reyes-Soto CY, Rangel-López E, Galván-Arzate S, Colín-González AL, Silva-Palacios A, Zazueta C, Pedraza-Chaverri J, Ramírez J, Chavarria A, Túnez I, Ke T, Aschner M, Santamaría A. S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidative Damage, Activation of Nrf2/ARE Binding, and BDNF Preservation. Neurotoxicity Research. PMID 32813208 DOI: 10.1007/S12640-020-00260-7  0.382
2020 Kostoff RN, Briggs MB, Porter AL, Hernández AF, Abdollahi M, Aschner M, Tsatsakis A. The Under-Reported Role of Toxic Substance Exposures in the COVID-19 Pandemic. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111687. PMID 32805343 DOI: 10.1016/J.Fct.2020.111687  0.303
2020 Ke T, Antunes Soares FA, Santamaría A, Bowman AB, Skalny AV, Aschner M. N,N' bis-(2-mercaptoethyl) isophthalamide induces developmental delay in by promoting DAF-16 nuclear localization. Toxicology Reports. 7: 930-937. PMID 32793422 DOI: 10.1016/J.Toxrep.2020.07.012  0.32
2020 Elmazoglu Z, Rangel-López E, Medina-Campos ON, Pedraza-Chaverri J, Túnez I, Aschner M, Santamaría A, Karasu Ç. Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ1-42 peptide in rat hippocampal neurons. Neurochemistry International. 140: 104817. PMID 32781098 DOI: 10.1016/J.Neuint.2020.104817  0.34
2020 Ke T, Santamaria A, Rocha JBT, Tinkov AA, Lu R, Bowman AB, Aschner M. The Role of Human LRRK2 in Methylmercury-Induced Inhibition of Microvesicle Formation of Cephalic Neurons in Caenorhabditis elegans. Neurotoxicity Research. PMID 32725544 DOI: 10.1007/S12640-020-00262-5  0.305
2020 Naime AA, Lopes MW, Colle D, Dafré AL, Suñol C, da Rocha JBT, Aschner M, Leal RB, Farina M. Glutathione in Chlorpyrifos-and Chlorpyrifos-Oxon-Induced Toxicity: a Comparative Study Focused on Non-cholinergic Toxicity in HT22 Cells. Neurotoxicity Research. PMID 32651842 DOI: 10.1007/S12640-020-00254-5  0.307
2020 Zheng F, Chen P, Li H, Aschner M. Drp-1 Dependent Mitochondrial Fragmentation Contributes to Cobalt Chloride Induced Toxicity in Caenorhabditis elegans. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32617571 DOI: 10.1093/Toxsci/Kfaa105  0.34
2020 Warren EB, Bryan MR, Morcillo P, Hardeman KN, Aschner M, Bowman AB. Manganese-induced mitochondrial dysfunction is not detectable at exposures below the acute cytotoxic threshold in neuronal cell types. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32492146 DOI: 10.1093/Toxsci/Kfaa079  0.362
2020 Hurtado-Díaz ME, Estrada-Valencia R, Rangel-López E, Maya-López M, Colonnello A, Galván-Arzate S, Verstraeten SV, Karasu C, Túnez I, Aschner M, Santamaría A. Thallium Toxicity in Caenorhabditis elegans: Involvement of the SKN-1 Pathway and Protection by S-Allylcysteine. Neurotoxicity Research. 38: 287-298. PMID 32468422 DOI: 10.1007/S12640-020-00220-1  0.332
2020 Liu T, Gao Q, Yang B, Yin C, Chang J, Qian H, Xing G, Wang S, Li F, Zhang Y, Chen D, Cai J, Shi H, Aschner M, Appiah-Kubi K, et al. Differential susceptibility of PC12 and BRL cells and the regulatory role of HIF-1α signaling pathway in response to acute methylmercury exposure under normoxia. Toxicology Letters. PMID 32461003 DOI: 10.1016/J.Toxlet.2020.05.023  0.327
2020 Tsatsakis A, Petrakis D, Nikolouzakis TK, Docea AO, Calina D, Vinceti M, Goumenou M, Kostoff RN, Mamoulakis C, Aschner M, Hernández AF. COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 141: 111418. PMID 32437891 DOI: 10.1016/J.Fct.2020.111418  0.326
2020 Oliveira CS, Segatto ALA, Nogara PA, Piccoli BC, Loreto ÉLS, Aschner M, Rocha JBT. Transcriptomic and Proteomic Tools in the Study of Hg Toxicity: What Is Missing? Frontiers in Genetics. 11: 425. PMID 32431728 DOI: 10.3389/Fgene.2020.00425  0.308
2020 Pfalzer AC, Wilcox JM, Codreanu SG, Totten M, Bichell TJV, Halbesma T, Umashanker P, Yang KL, Parmalee NL, Sherrod SD, Erikson KM, Harrison FE, McLean JA, Aschner M, Bowman AB. Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice. Metallomics : Integrated Biometal Science. PMID 32421118 DOI: 10.1039/D0Mt00081G  0.335
2020 Zheng F, Gonçalves FM, Abiko Y, Li H, Kumagai Y, Aschner M. Redox toxicology of environmental chemicals causing oxidative stress. Redox Biology. 101475. PMID 32336668 DOI: 10.1016/J.Redox.2020.101475  0.349
2020 Kostoff RN, Aschner M, Goumenou M, Tsatsakis A. Setting safer exposure limits for toxic substance combinations. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111346. PMID 32334109 DOI: 10.1016/J.Fct.2020.111346  0.321
2020 Chen S, Li D, Wu X, Chen L, Zhang B, Tan Y, Yu D, Niu Y, Duan H, Li Q, Chen R, Aschner M, Zheng Y, Chen W. Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China. Environment International. 139: 105703. PMID 32259755 DOI: 10.1016/J.Envint.2020.105703  0.328
2020 Ke T, Bornhorst J, Schwerdtle T, Santamaría A, Soare FAA, Rocha JBT, Farina M, Bowman AB, Aschner M. Therapeutic Efficacy of the N,N' Bis-(2-Mercaptoethyl) Isophthalamide Chelator for Methylmercury Intoxication in Caenorhabditis elegans. Neurotoxicity Research. PMID 32236898 DOI: 10.1007/S12640-020-00194-0  0.358
2020 Bornhorst J, Ebert F, Meyer S, Ziemann V, Xiong C, Guttenberger N, Raab A, Baesler J, Aschner M, Feldmann J, Francesconi K, Raber G, Schwerdtle T. Toxicity of three types of arsenolipids: species-specific effects in Caenorhabditis elegans. Metallomics. 12: 794-798. PMID 32232250 DOI: 10.1039/D0Mt00039F  0.307
2020 Taylor CA, Tuschl K, Nicolai MM, Bornhorst J, Gubert P, Varão AM, Aschner M, Smith DR, Mukhopadhyay S. Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity. The Journal of Nutrition. PMID 32211802 DOI: 10.1093/Jn/Nxaa066  0.364
2020 Ijomone OM, Miah MR, Akingbade GT, Bucinca H, Aschner M. Nickel-Induced Developmental Neurotoxicity in C. elegans Includes Cholinergic, Dopaminergic and GABAergic Degeneration, Altered Behaviour, and Increased SKN-1 Activity. Neurotoxicity Research. 37: 1018-1028. PMID 32034695 DOI: 10.1007/S12640-020-00175-3  0.376
2020 Abolaji AO, Fasae KD, Iwezor CE, Aschner M, Farombi EO. Curcumin attenuates copper-induced oxidative stress and neurotoxicity in Drosophila melanogaster. Toxicology Reports. 7: 261-268. PMID 32025502 DOI: 10.1016/J.Toxrep.2020.01.015  0.314
2020 Afolabi BA, Olagoke OC, Souza DO, Aschner M, Rocha JBT, Segatto ALA. Modified expression of antioxidant genes in lobster cockroach, Nauphoeta cinerea exposed to methylmercury and monosodium glutamate. Chemico-Biological Interactions. 108969. PMID 32007422 DOI: 10.1016/J.Cbi.2020.108969  0.328
2020 Miah MR, Ijomone OM, Okoh COA, Ijomone OK, Akingbade GT, Ke T, Krum B, da Cunha Martins A, Akinyemi A, Aranoff N, Antunes Soares FA, Bowman AB, Aschner M. The effects of manganese overexposure on brain health. Neurochemistry International. 104688. PMID 31972215 DOI: 10.1016/J.Neuint.2020.104688  0.384
2020 Neumann C, Baesler J, Steffen G, Nicolai MM, Zubel T, Aschner M, Bürkle A, Mangerich A, Schwerdtle T, Bornhorst J. The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans. Journal of Trace Elements in Medicine and Biology. 57: 21-27. PMID 31546209 DOI: 10.1016/J.Jtemb.2019.09.001  0.365
2020 Ali SF, Jiang H, Rongzhu L, Milatovic D, Aschner M. Methamphetamine Dysregulates Redox Status in Primary Rat Astrocyte and Mesencephalic Neuronal Cultures. American Journal of Neuroprotection and Neuroregeneration. 1: 52-59. PMID 30627316 DOI: 10.1166/Ajnn.2009.1004  0.372
2019 Zanfirescu A, Ungurianu A, Tsatsakis AM, Nițulescu GM, Kouretas D, Veskoukis A, Tsoukalas D, Engin AB, Aschner M, Margină D. A review of the alleged health hazards of monosodium glutamate. Comprehensive Reviews in Food Science and Food Safety. 18: 1111-1134. PMID 31920467 DOI: 10.1111/1541-4337.12448  0.31
2019 Piccoli BC, Segatto ALA, Oliveira CS, D'Avila da Silva F, Aschner M, da Rocha JBT. Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses. Bmc Pharmacology & Toxicology. 20: 83. PMID 31852533 DOI: 10.1186/S40360-019-0356-0  0.337
2019 Chang J, Yang B, Zhou Y, Yin C, Liu T, Qian H, Xing G, Wang S, Li F, Zhang Y, Chen D, Aschner M, Lu R. Acute Methylmercury Exposure and the Hypoxia-Inducible Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes . Environmental Health Perspectives. 127: 127006. PMID 31850806 DOI: 10.1289/Ehp5139  0.364
2019 Piccoli BC, Alvim JC, da Silva FD, Nogara PA, Olagoke OC, Aschner M, Oliveira CS, Rocha JBT. High level of methylmercury exposure causes persisted toxicity in Nauphoeta cinerea. Environmental Science and Pollution Research International. PMID 31845250 DOI: 10.1007/S11356-019-06989-9  0.318
2019 Ijomone OM, Aluko OM, Okoh COA, Martins AC, Aschner M. Role for calcium signaling in manganese neurotoxicity. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 56: 146-155. PMID 31470248 DOI: 10.1016/J.Jtemb.2019.08.006  0.326
2019 Akinyemi AJ, Miah MR, Ijomone OM, Tsatsakis A, Soares FAA, Tinkov AA, Skalny AV, Venkataramani V, Aschner M. Lead (Pb) exposure induces dopaminergic neurotoxicity in Caenorhabditis elegans: Involvement of the dopamine transporter Toxicology Reports. 6: 833-840. PMID 31463204 DOI: 10.1016/J.Toxrep.2019.08.001  0.369
2019 Aschner M, Carvalho C. The biochemistry of mercury toxicity. Biochimica Et Biophysica Acta. 1863: 129412. PMID 31401179 DOI: 10.1016/J.Bbagen.2019.129412  0.302
2019 Rizor A, Pajarillo E, Johnson J, Aschner M, Lee E. Astrocytic Oxidative/Nitrosative Stress Contributes to Parkinson's Disease Pathogenesis: The Dual Role of Reactive Astrocytes. Antioxidants (Basel, Switzerland). 8. PMID 31374936 DOI: 10.3390/Antiox8080265  0.323
2019 Baesler J, Kopp JF, Pohl G, Aschner M, Haase H, Schwerdtle T, Bornhorst J. Zn homeostasis in genetic models of Parkinson’s disease in Caenorhabditis elegans Journal of Trace Elements in Medicine and Biology. 55: 44-49. PMID 31345364 DOI: 10.1016/J.Jtemb.2019.05.005  0.305
2019 Erukainure OL, Ijomone OM, Sanni O, Aschner M, Islam MS. Type 2 diabetes induced oxidative brain injury involves altered cerebellar neuronal integrity and elemental distribution, and exacerbated Nrf2 expression: therapeutic potential of raffia palm (Raphia hookeri) wine. Metabolic Brain Disease. PMID 31201727 DOI: 10.1007/S11011-019-00444-X  0.347
2019 Li X, Cui J, Yang H, Sun H, Lu R, Gao N, Meng Q, Wu S, Wu J, Aschner M, Chen R. Colonic Injuries Induced by Inhalational Exposure to Particulate-Matter Air Pollution. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1900180. PMID 31179224 DOI: 10.1002/Advs.201900180  0.319
2019 Erukainure OL, Ijomone OM, Oyebode OA, Chukwuma CI, Aschner M, Islam MS. Hyperglycemia-induced oxidative brain injury: Therapeutic effects of Cola nitida infusion against redox imbalance, cerebellar neuronal insults, and upregulated Nrf2 expression in type 2 diabetes rats. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 30914353 DOI: 10.1016/J.Fct.2019.03.044  0.317
2019 Li D, Zhang R, Cui L, Chu C, Zhang H, Sun H, Luo J, Zhou L, Chen L, Cui J, Chen S, Mai B, Chen S, Yu J, Cai Z, ... ... Aschner M, et al. Multiple organ injury in male C57BL/6J mice exposed to ambient particulate matter in a real-ambient PM exposure system in Shijiazhuang, China. Environmental Pollution (Barking, Essex : 1987). 248: 874-887. PMID 30856503 DOI: 10.1016/J.Envpol.2019.02.097  0.32
2019 Erikson KM, Aschner M. Manganese: Its Role in Disease and Health. Metal Ions in Life Sciences. 19. PMID 30855111 DOI: 10.1515/9783110527872-016  0.361
2019 Pajarillo E, Rizor A, Lee J, Aschner M, Lee E. The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: potential targets for neurotherapeutics. Neuropharmacology. PMID 30851309 DOI: 10.1016/J.Neuropharm.2019.03.002  0.328
2019 Zheng F, Luo Z, Zheng C, Li J, Zeng J, Yang H, Chen J, Jin Y, Aschner M, Wu S, Zhang Q, Li H. Comparison of the neurotoxicity associated with cobalt nanoparticles and cobalt chloride in Wistar rats. Toxicology and Applied Pharmacology. PMID 30849457 DOI: 10.1016/J.Taap.2019.03.003  0.362
2019 Chen P, Totten M, Zhang Z, Bucinca H, Erikson K, Santamaría A, Bowman AB, Aschner M. Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment. Expert Review of Neurotherapeutics. PMID 30759034 DOI: 10.1080/14737175.2019.1581608  0.334
2019 Prince LM, Aschner M, Bowman AB. Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmercury. Biochimica Et Biophysica Acta. General Subjects. PMID 30742955 DOI: 10.1016/J.Bbagen.2019.02.002  0.331
2019 Farina M, Aschner M. Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay. Biochimica Et Biophysica Acta. 1863: 129285. PMID 30659883 DOI: 10.1016/J.Bbagen.2019.01.007  0.352
2019 Kim J, Pajarillo E, Rizor A, Son DS, Lee J, Aschner M, Lee E. LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia. Plos One. 14: e0210248. PMID 30645642 DOI: 10.1371/Journal.Pone.0210248  0.349
2019 Ruszkiewicz JA, Miranda-Vizuete A, Tinkov AA, Skalnaya MG, Skalny AV, Tsatsakis A, Aschner M. Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease. Journal of Molecular Neuroscience. 67: 312-342. PMID 30604380 DOI: 10.1007/S12031-018-1241-9  0.307
2019 Tinkov AA, Ajsuvakova OP, Skalnaya MG, Skalny AV, Aschner M, Suliburska J, Aaseth J. Organotins in obesity and associated metabolic disturbances Journal of Inorganic Biochemistry. 191: 49-59. PMID 30458368 DOI: 10.1016/J.Jinorgbio.2018.11.002  0.316
2018 Cui J, Fu Y, Lu R, Bi Y, Zhang L, Zhang C, Aschner M, Li X, Chen R. Metabolomics analysis explores the rescue to neurobehavioral disorder induced by maternal PM exposure in mice. Ecotoxicology and Environmental Safety. 169: 687-695. PMID 30500738 DOI: 10.1016/J.Ecoenv.2018.11.037  0.332
2018 Ke T, Gonçalves FM, Gonçalves CL, Dos Santos AA, Rocha JBT, Farina M, Skalny A, Tsatsakis A, Bowman AB, Aschner M. Post-translational modifications in MeHg-induced neurotoxicity. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30385410 DOI: 10.1016/J.Bbadis.2018.10.024  0.364
2018 Fu Y, Lu R, Cui J, Sun H, Yang H, Meng Q, Wu S, Aschner M, Li X, Chen R. Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM-induced epithelial-mesenchymal transition. Ecotoxicology and Environmental Safety. 167: 309-316. PMID 30343145 DOI: 10.1016/J.Ecoenv.2018.10.033  0.323
2018 Schetinger MRC, Peres TV, Arantes LP, Carvalho F, Dressler V, Heidrich G, Bowman AB, Aschner M. Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, cholinergic and monoaminergic up-regulation and oxidative stress in L4 Caenorhabditis elegans. Toxicology. PMID 30336192 DOI: 10.1016/J.Tox.2018.10.006  0.375
2018 Serrazina DC, Lopes De Andrade V, Cota M, Mateus ML, Aschner M, Dos Santos APM. Biomarkers of exposure and effect in a working population exposed to lead, manganese and arsenic. Journal of Toxicology and Environmental Health. Part A. 1-15. PMID 30296394 DOI: 10.1080/15287394.2018.1509408  0.346
2018 Unoki T, Akiyama M, Kumagai Y, Gonçalves FM, Farina M, da Rocha JBT, Aschner M. Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation. Frontiers in Genetics. 9: 373. PMID 30271424 DOI: 10.3389/Fgene.2018.00373  0.387
2018 Ijomone OM, Olatunji SY, Owolabi JO, Naicker T, Aschner M. Nickel-induced neurodegeneration in the hippocampus, striatum and cortex; an ultrastructural insight, and the role of caspase-3 and α-synuclein. Journal of Trace Elements in Medicine and Biology. 50: 16-23. PMID 30262274 DOI: 10.1016/J.Jtemb.2018.05.017  0.339
2018 Ruszkiewicz JA, Teixeira de Macedo G, Miranda-Vizuete A, Bowman AB, Bornhorst J, Schwerdtle T, Antunes Soares FA, Aschner M. Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity. Neurotoxicity Research. PMID 30155682 DOI: 10.1007/S12640-018-9949-4  0.301
2018 Ruszkiewicz JA, Teixeira de Macedo G, Miranda-Vizuete A, Teixeira da Rocha JB, Bowman AB, Bornhorst J, Schwerdtle T, Aschner M. The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner. Neurotoxicology. 68: 189-202. PMID 30138651 DOI: 10.1016/J.Neuro.2018.08.007  0.35
2018 Antunes Dos Santos A, Ferrer B, Marques Gonçalves F, Tsatsakis AM, Renieri EA, Skalny AV, Farina M, Rocha JBT, Aschner M. Oxidative Stress in Methylmercury-Induced Cell Toxicity. Toxics. 6. PMID 30096882 DOI: 10.3390/Toxics6030047  0.357
2018 Pinkas A, Martins AC, Aschner M. C. elegans—An Emerging Model to Study Metal-Induced RAGE-Related Pathologies International Journal of Environmental Research and Public Health. 15: 1407. PMID 29973513 DOI: 10.3390/Ijerph15071407  0.346
2018 Colonnello A, Kotlar I, Lima MEd, Ortíz-Plata A, García-Contreras R, Soares FAA, Aschner M, Santamaría A. Comparing the Effects of Ferulic Acid and Sugarcane Aqueous Extract in In Vitro and In Vivo Neurotoxic Models Neurotoxicity Research. 34: 640-648. PMID 29949107 DOI: 10.1007/S12640-018-9926-Y  0.367
2018 Peres TV, Arantes LP, Miah MR, Bornhorst J, Schwerdtle T, Bowman AB, Leal RB, Aschner M. Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity. Neurotoxicity Research. PMID 29882004 DOI: 10.1007/S12640-018-9915-1  0.354
2018 Pinkas A, Lee KH, Chen P, Aschner M. A C. elegans Model for the Study of RAGE-Related Neurodegeneration. Neurotoxicity Research. PMID 29869225 DOI: 10.1007/S12640-018-9918-Y  0.316
2018 Ferrer B, Peres TV, Dos Santos AA, Bornhorst J, Morcillo P, Gonçalves CL, Aschner M. Methylmercury Affects the Expression of Hypothalamic Neuropeptides That Control Body Weight in C57BL/6J Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 163: 557-568. PMID 29850906 DOI: 10.1093/Toxsci/Kfy052  0.313
2018 Johnson J, Pajarillo E, Karki P, Kim J, Son DS, Aschner M, Lee E. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. PMID 29778792 DOI: 10.1016/J.Neuro.2018.05.001  0.403
2018 Rohn I, Marschall TA, Kroepfl N, Jensen KB, Aschner M, Tuck S, Kuehnelt D, Schwerdtle T, Bornhorst J. Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans Metallomics. 10: 818-827. PMID 29770420 DOI: 10.1039/C8Mt00066B  0.308
2018 Yang B, Bai Y, Yin C, Qian H, Xing G, Wang S, Li F, Bian J, Aschner M, Lu R. Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes. Archives of Toxicology. PMID 29725710 DOI: 10.1007/S00204-018-2208-X  0.369
2018 da Silveira TL, Zamberlan DC, Arantes LP, Machado ML, da Silva TC, Câmara DF, Santamaría A, Aschner M, Soares FAA. Quinolinic Acid and glutamatergic neurodegeneration in Caenorhabditis elegans. Neurotoxicology. PMID 29702159 DOI: 10.1016/J.Neuro.2018.04.015  0.324
2018 Gubert P, Puntel B, Lehmen T, Fessel JP, Cheng P, Bornhorst J, Trindade LS, Avila DS, Aschner M, Soares FAA. Metabolic effects of manganese in the nematode Caenorhabditis elegans through DAergic pathway and transcription factors activation. Neurotoxicology. PMID 29673961 DOI: 10.1016/J.Neuro.2018.04.008  0.344
2018 Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg H, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, et al. Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes. Toxicology and Applied Pharmacology. PMID 29447839 DOI: 10.1016/J.Taap.2018.02.004  0.317
2018 Lucchini RG, Aschner M, Landrigan PJ, Cranmer JM. Neurotoxicity of manganese: Indications for future research and public health intervention from the Manganese 2016 conference. Neurotoxicology. 64: 1-4. PMID 29429640 DOI: 10.1016/J.Neuro.2018.01.002  0.359
2018 Antunes Dos Santos A, López-Granero C, Farina M, Rocha JBT, Bowman AB, Aschner M. Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 29428217 DOI: 10.1016/J.Fct.2018.01.057  0.355
2018 Chen P, Bornhorst J, Aschner M. Manganese metabolism in humans. Frontiers in Bioscience (Landmark Edition). 23: 1655-1679. PMID 29293455 DOI: 10.2741/4665  0.363
2018 Kotlar I, Colonnello A, Aguilera-González MF, Avila DS, Lima MEd, García-Contreras R, Ortíz-Plata A, Soares FAA, Aschner M, Santamaría A. Comparison of the Toxic Effects of Quinolinic Acid and 3-Nitropropionic Acid in C. elegans: Involvement of the SKN-1 Pathway. Neurotoxicity Research. 33: 259-267. PMID 28822104 DOI: 10.1007/S12640-017-9794-X  0.318
2017 Liu X, Su P, Meng S, Aschner M, Cao Y, Luo W, Zheng G, Liu M. Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain barrier model. International Journal of Biological Sciences. 13: 1351-1360. PMID 29209140 DOI: 10.7150/Ijbs.20670  0.326
2017 Pajarillo E, Johnson J, Kim J, Karki P, Son DS, Aschner M, Lee E. 17β-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity. Neurotoxicology. PMID 29183790 DOI: 10.1016/J.Neuro.2017.11.008  0.36
2017 Pesch B, Casjens S, Weiss T, Kendzia B, Arendt M, Eisele L, Behrens T, Ulrich N, Pundt N, Marr A, Robens S, Thriel CV, Gelder RV, Aschner M, Moebus S, et al. Occupational Exposure to Manganese and Fine Motor Skills in Elderly Men: Results from the Heinz Nixdorf Recall Study Annals of Work Exposures and Health. 61: 1118-1131. PMID 29136419 DOI: 10.1093/Annweh/Wxx076  0.316
2017 Klimaczewski CV, Ecker A, Piccoli B, Aschner M, Barbosa NV, Rocha JBT. Peumus boldus attenuates copper-induced toxicity in Drosophila melanogaster. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 97: 1-8. PMID 29080449 DOI: 10.1016/J.Biopha.2017.09.130  0.301
2017 Li X, Yang H, Sun H, Lu R, Zhang C, Gao N, Meng Q, Wu S, Wang S, Aschner M, Wu J, Tang B, Gu A, Kay SA, Chen R. Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078374 DOI: 10.1073/Pnas.1712465114  0.309
2017 Caito S, Park M, Aschner M. Resistance of mouse primary microglia and astrocytes to acrylonitrile-induced oxidative stress. Neurotoxicology. PMID 28965700 DOI: 10.1016/J.Neuro.2017.09.013  0.335
2017 Ruszkiewicz JA, Pinkas A, Ferrer B, Peres TV, Tsatsakis A, Aschner M. Neurotoxic effect of active ingredients in sunscreen products, a contemporary review Toxicology Reports. 4: 245-259. PMID 28959646 DOI: 10.1016/J.Toxrep.2017.05.006  0.302
2017 Farina M, Aschner M. Methylmercury-Induced Neurotoxicity: Focus on Pro-oxidative Events and Related Consequences. Advances in Neurobiology. 18: 267-286. PMID 28889272 DOI: 10.1007/978-3-319-60189-2_13  0.342
2017 Andrade VM, Aschner M, Marreilha Dos Santos AP. Neurotoxicity of Metal Mixtures. Advances in Neurobiology. 18: 227-265. PMID 28889271 DOI: 10.1007/978-3-319-60189-2_12  0.344
2017 Oliveira CS, Piccoli BC, Aschner M, Rocha JBT. Chemical Speciation of Selenium and Mercury as Determinant of Their Neurotoxicity. Advances in Neurobiology. 18: 53-83. PMID 28889263 DOI: 10.1007/978-3-319-60189-2_4  0.333
2017 Caito S, Aschner M. Developmental Neurotoxicity of Lead Advances in Neurobiology. 18: 3-12. PMID 28889260 DOI: 10.1007/978-3-319-60189-2_1  0.338
2017 Liu C, Hutchens S, Jursa T, Shawlot W, Polishchuk EV, Polishchuk RS, Dray BK, Gore AC, Aschner M, Smith DR, Mukhopadhyay S. Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by reduced thyroxine production. The Journal of Biological Chemistry. PMID 28860195 DOI: 10.1074/Jbc.M117.804989  0.318
2017 Da Silva ALC, Urbano MR, Almeida Lopes ACB, Carvalho MFH, Buzzo ML, Peixe TS, Aschner M, Mesas AE, Paoliello MMB. Blood manganese levels and associated factors in a population-based study in Southern Brazil. Journal of Toxicology and Environmental Health. Part A. 1-14. PMID 28850015 DOI: 10.1080/15287394.2017.1357354  0.309
2017 Lee E, Karki P, Johnson J, Hong P, Aschner M. Manganese Control of Glutamate Transporters' Gene Expression. Advances in Neurobiology. 16: 1-12. PMID 28828603 DOI: 10.1007/978-3-319-55769-4_1  0.38
2017 Karki P, Hong P, Johnson J, Pajarillo E, Son DS, Aschner M, Lee EY. Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways. Molecular Neurobiology. PMID 28812276 DOI: 10.1007/S12035-017-0709-X  0.328
2017 Culbreth M, Zhang Z, Aschner M. Methylmercury augments Nrf2 activity by downregulation of the Src family kinase Fyn. Neurotoxicology. PMID 28736149 DOI: 10.1016/J.Neuro.2017.07.028  0.312
2017 Caito S, Lopes ACBA, Paoliello MMB, Aschner M. Toxicology of Lead and Its Damage to Mammalian Organs. Metal Ions in Life Sciences. 17: 501-534. PMID 28731309 DOI: 10.1515/9783110434330-016  0.354
2017 Li SJ, Qin WX, Peng DJ, Yuan ZX, He SN, Luo YN, Aschner M, Jiang YM, Liang DY, Xie BY, Xu F. Sodium P-aminosalicylic acid inhibits sub-chronic manganese-induced neuroinflammation in rats by modulating MAPK and COX-2. Neurotoxicology. PMID 28651968 DOI: 10.1016/J.Neuro.2017.06.012  0.341
2017 Johnson J, Pajarillo EAB, Taka E, Reams R, Son DS, Aschner M, Lee E. Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice. Neurotoxicology. PMID 28610743 DOI: 10.1016/J.Neuro.2017.06.007  0.369
2017 Salgueiro WG, Goldani BS, Peres TV, Miranda-Vizuete A, Aschner M, da Rocha JBT, Alves D, Ávila DS. Insights Into the Differential Toxicological and Antioxidant Effects of 4-phenylchalcogenil-7-chloroquinolines in Caenorhabditis elegans. Free Radical Biology & Medicine. PMID 28571752 DOI: 10.1016/J.Freeradbiomed.2017.05.020  0.339
2017 Hutchens S, Liu C, Jursa T, Shawlot W, Chaffee BK, Yin W, Gore AC, Aschner M, Smith DR, Mukhopadhyay S. Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice. The Journal of Biological Chemistry. PMID 28461334 DOI: 10.1074/Jbc.M117.783605  0.329
2017 Meinerz DF, Branco V, Aschner M, Carvalho C, Rocha JB. Diphenyl diselenide protects against methylmercury-induced inhibition of thioredoxin reductase and glutathione peroxidase in human neuroblastoma cells: a comparison with ebselen. Journal of Applied Toxicology : Jat. PMID 28383113 DOI: 10.1002/Jat.3458  0.389
2017 Branco V, Caito S, Farina M, Rocha JBTd, Aschner M, Carvalho C. Biomarkers of mercury toxicity: Past, present, and future trends. Journal of Toxicology and Environmental Health-Part B-Critical Reviews. 20: 119-154. PMID 28379072 DOI: 10.1080/10937404.2017.1289834  0.328
2017 Ruszkiewicz JA, Li S, Rodriguez MB, Aschner M. Is Triclosan a neurotoxic agent? Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 20: 104-117. PMID 28339349 DOI: 10.1080/10937404.2017.1281181  0.349
2017 Casjens S, Pesch B, Robens S, Kendzia B, Behrens T, Weiss T, Ulrich N, Arendt M, Eisele L, Pundt N, Marr A, Thriel Cv, Gelder RV, Aschner M, Moebus S, et al. Associations between former exposure to manganese and olfaction in an elderly population: Results from the Heinz Nixdorf Recall Study Neurotoxicology. 58: 58-65. PMID 27865828 DOI: 10.1016/J.Neuro.2016.11.005  0.329
2016 Arantes LP, Peres TV, Chen P, Caito S, Aschner M, Soares FA. Guarana (Paullinia cupana Mart.) attenuates methylmercury-induced toxicity in Caenorhabditis elegans. Toxicology Research. 5: 1629-1638. PMID 28316775 DOI: 10.1039/C6Tx00161K  0.35
2016 Culbreth M, Aschner M. Dysregulation of Glutamate Cycling Mediates Methylmercury-Induced Neurotoxicity. Advances in Neurobiology. 13: 295-305. PMID 27885634 DOI: 10.1007/978-3-319-45096-4_11  0.343
2016 Peres TV, Schettinger MR, Chen P, Carvalho F, Avila DS, Bowman AB, Aschner M. "Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies". Bmc Pharmacology & Toxicology. 17: 57. PMID 27814772 DOI: 10.1186/S40360-016-0099-0  0.401
2016 Ijomone OM, Miah MR, Peres TV, Nwoha PU, Aschner M. Null allele mutants of trt-1, the catalytic subunit of telomerase in Caenorhabditis elegans, are less sensitive to Mn-induced toxicity and DAergic degeneration. Neurotoxicology. 57: 54-60. PMID 27593554 DOI: 10.1016/J.Neuro.2016.08.016  0.351
2016 Peres TV, Parmalee NL, Martinez-Finley EJ, Aschner M. Untangling the Manganese-α-Synuclein Web. Frontiers in Neuroscience. 10: 364. PMID 27540354 DOI: 10.3389/Fnins.2016.00364  0.317
2016 Parmalee NL, Aschner M. Manganese and aging Neurotoxicology. 56: 262-268. PMID 27293182 DOI: 10.1016/J.Neuro.2016.06.006  0.359
2016 Yu B, Wenjun Z, Changsheng Y, Yuntao F, Jing M, Ben L, Hai Q, Guangwei X, Suhua W, Fang L, Aschner M, Rongzhu L. Preconditioning of endoplasmic reticulum stress protects against acrylonitrile-induced cytotoxicity in primary rat astrocytes: the role of autophagy. Neurotoxicology. PMID 27260289 DOI: 10.1016/J.Neuro.2016.05.020  0.341
2016 Adedara IA, Rosemberg DB, de Souza D, Farombi EO, Aschner M, Souza DO, Rocha JB. Neurobehavioral and biochemical changes in Nauphoeta cinerea following dietary exposure to chlorpyrifos. Pesticide Biochemistry and Physiology. 130: 22-30. PMID 27155480 DOI: 10.1016/J.Pestbp.2015.12.004  0.348
2016 Chen P, Culbreth M, Aschner M. Exposure, epidemiology, and mechanism of the environmental toxicant manganese. Environmental Science and Pollution Research International. PMID 27102617 DOI: 10.1007/S11356-016-6687-0  0.401
2016 Kraft AD, Aschner M, Cory-Slechta DA, Bilbo SD, Caudle WM, Makris SL. Unmasking silent neurotoxicity following developmental exposure to environmental toxicants. Neurotoxicology and Teratology. PMID 27049787 DOI: 10.1016/J.Ntt.2016.03.005  0.333
2016 Antunes Dos Santos A, Appel Hort M, Culbreth M, López-Granero C, Farina M, Rocha JB, Aschner M. Methylmercury and brain development: A review of recent literature. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). PMID 26987277 DOI: 10.1016/J.Jtemb.2016.03.001  0.384
2016 Gubert P, Puntel B, Lehmen T, Bornhorst J, Avila DS, Aschner M, Soares FA. Reversible reprotoxic effects of manganese through DAF-16 transcription factor activation and vitellogenin downregulation in Caenorhabditis elegans. Life Sciences. 151: 218-23. PMID 26972607 DOI: 10.1016/J.Lfs.2016.03.016  0.332
2016 Song H, Zheng G, Liu Y, Shen XF, Zhao ZH, Aschner M, Luo WJ, Chen JY. Cellular uptake of lead in the blood-cerebrospinal fluid barrier: Novel roles of Connexin 43 hemichannel and its down-regulations via Erk phosphorylation. Toxicology and Applied Pharmacology. PMID 26926986 DOI: 10.1016/J.Taap.2016.02.021  0.387
2016 Adedara IA, Rosemberg DB, Souza DO, Farombi EO, Aschner M, Rocha JB. Neuroprotection of luteolin against methylmercury-induced toxicity in lobster cockroach Nauphoeta cinerea. Environmental Toxicology and Pharmacology. 42: 243-251. PMID 26905302 DOI: 10.1016/J.Etap.2016.02.001  0.363
2016 Zhang Z, Miah M, Culbreth M, Aschner M. Autophagy in Neurodegenerative Diseases and Metal Neurotoxicity. Neurochemical Research. PMID 26869037 DOI: 10.1007/S11064-016-1844-X  0.368
2016 Caito SW, Aschner M. NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26865665 DOI: 10.1093/Toxsci/Kfw030  0.406
2016 Su P, Zhang J, Wang S, Aschner M, Cao Z, Zhao F, Wang D, Chen J, Luo W. Genistein alleviates lead-induced neurotoxicity in vitro and in vivo: Involvement of multiple signaling pathways. Neurotoxicology. PMID 26797587 DOI: 10.1016/J.Neuro.2015.12.019  0.399
2016 Peres TV, Ong LK, Costa AP, Eyng H, Venske DK, Colle D, Gonçalves FM, Lopes MW, Farina M, Aschner M, Dickson PW, Dunkley PR, Leal RB. Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese. Metallomics : Integrated Biometal Science. PMID 26790482 DOI: 10.1039/C5Mt00265F  0.371
2016 López-Granero C, Ruiz-Muñoz AM, Nieto-Escámez FA, Colomina MT, Aschner M, Sánchez-Santed F. Chronic dietary chlorpyrifos causes long-term spatial memory impairment and thigmotaxic behavior. Neurotoxicology. 53: 85-92. PMID 26748072 DOI: 10.1016/J.Neuro.2015.12.016  0.305
2016 Aschner M. S11-2 Manganese-induced neurotoxicity: lessons from worms Occupational and Environmental Medicine. 73. DOI: 10.1136/Oemed-2016-103951.304  0.398
2015 Caito S, Aschner M. Neurotoxicity of metals. Handbook of Clinical Neurology. 131: 169-89. PMID 26563789 DOI: 10.1016/B978-0-444-62627-1.00011-1  0.339
2015 Schumacher F, Chakraborty S, Kleuser B, Gulbins E, Schwerdtle T, Aschner M, Bornhorst J. Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans. Talanta. 144: 71-9. PMID 26452793 DOI: 10.1016/J.Talanta.2015.05.057  0.303
2015 Yu B, Changsheng Y, Wenjun Z, Ben L, Hai Q, Jing M, Guangwei X, Shuhua W, Fang L, Aschner M, Rongzhu L. Differential protection of pre- versus post-treatment with curcumin, Trolox, and N-acetylcysteine against acrylonitrile-induced cytotoxicity in primary rat astrocytes. Neurotoxicology. 51: 58-66. PMID 26409646 DOI: 10.1016/J.Neuro.2015.09.011  0.346
2015 Karki P, Kim C, Smith K, Son DS, Aschner M, Lee E. Transcriptional regulation of the astrocytic excitatory amino acid transporter 1 (EAAT1) via NF-kB and Yin Yang 1 (YY1). The Journal of Biological Chemistry. PMID 26269591 DOI: 10.1074/Jbc.M115.649327  0.323
2015 Parmalee NL, Maqbool SB, Ye B, Calder B, Bowman AB, Aschner M. RNASeq in C. elegans Following Manganese Exposure. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 65: 11.20.1-11.20.17. PMID 26250396 DOI: 10.1002/0471140856.Tx1120S65  0.371
2015 Peres TV, Eyng H, Lopes SC, Colle D, Gonçalves FM, Venske DK, Lopes MW, Ben J, Bornhorst J, Schwerdtle T, Aschner M, Farina M, Prediger RD, Leal RB. Developmental exposure to manganese induces lasting motor and cognitive impairment in rats. Neurotoxicology. 50: 28-37. PMID 26215118 DOI: 10.1016/J.Neuro.2015.07.005  0.378
2015 Kwakye GF, Paoliello MM, Mukhopadhyay S, Bowman AB, Aschner M. Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features. International Journal of Environmental Research and Public Health. 12: 7519-40. PMID 26154659 DOI: 10.3390/Ijerph120707519  0.404
2015 Chen P, Chakraborty S, Mukhopadhyay S, Lee E, Paoliello MM, Bowman AB, Aschner M. Manganese homeostasis in the nervous system. Journal of Neurochemistry. 134: 601-10. PMID 25982296 DOI: 10.1111/Jnc.13170  0.388
2015 Su P, Zhao F, Cao Z, Zhang J, Aschner M, Luo W. Mir-203-mediated tricellulin mediates lead-induced in vitro loss of blood-cerebrospinal fluid barrier (BCB) function. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 1185-94. PMID 25975750 DOI: 10.1016/J.Tiv.2015.05.002  0.316
2015 Horning KJ, Caito SW, Tipps KG, Bowman AB, Aschner M. Manganese Is Essential for Neuronal Health. Annual Review of Nutrition. 35: 71-108. PMID 25974698 DOI: 10.1146/Annurev-Nutr-071714-034419  0.423
2015 Chen P, Chakraborty S, Peres TV, Bowman AB, Aschner M. Manganese-induced Neurotoxicity: From C. elegans to Humans. Toxicology Research. 4: 191-202. PMID 25893090 DOI: 10.1039/C4Tx00127C  0.439
2015 Dimovasili C, Aschner M, Plaitakis A, Zaganas I. Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity. Neurochemistry International. 88: 60-5. PMID 25837286 DOI: 10.1016/J.Neuint.2015.03.004  0.333
2015 Caito SW, Aschner M. Mitochondrial Redox Dysfunction and Environmental Exposures. Antioxidants & Redox Signaling. 23: 578-95. PMID 25826672 DOI: 10.1089/Ars.2015.6289  0.307
2015 Chakraborty S, Chen P, Bornhorst J, Schwerdtle T, Schumacher F, Kleuser B, Bowman AB, Aschner M. Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans. Metallomics : Integrated Biometal Science. 7: 847-56. PMID 25769119 DOI: 10.1039/C5Mt00052A  0.41
2015 Andrade VM, Mateus ML, Batoréu MC, Aschner M, Santos APMd. Lead, Arsenic, and Manganese Metal Mixture Exposures: Focus on Biomarkers of Effect. Biological Trace Element Research. 166: 13-23. PMID 25693681 DOI: 10.1007/S12011-015-0267-X  0.363
2015 Kumar KK, Goodwin CR, Uhouse MA, Bornhorst J, Schwerdtle T, Aschner M, McLean JA, Bowman AB. Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. Metallomics : Integrated Biometal Science. 7: 363-70. PMID 25599126 DOI: 10.1039/C4Mt00223G  0.413
2015 Reckziegel P, Chen P, Caito S, Gubert P, Soares FA, Fachinetto R, Aschner M. Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in Caenorhabditis elegans. Archives of Toxicology. PMID 25579234 DOI: 10.1007/S00204-015-1451-7  0.323
2015 Chen P, DeWitt MR, Bornhorst J, Soares FA, Mukhopadhyay S, Bowman AB, Aschner M. Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease. Metallomics : Integrated Biometal Science. 7: 289-98. PMID 25531510 DOI: 10.1039/C4Mt00292J  0.361
2015 Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Human Molecular Genetics. 24: 1929-44. PMID 25489053 DOI: 10.1093/Hmg/Ddu609  0.354
2015 Karki P, Smith K, Johnson J, Aschner M, Lee E. Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity. Neurochemistry International. 88: 53-9. PMID 25128239 DOI: 10.1016/J.Neuint.2014.08.002  0.393
2015 Karki P, Smith K, Johnson J, Aschner M, Lee EY. Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurological disorders and manganese toxicity. Neurochemical Research. 40: 380-8. PMID 25064045 DOI: 10.1007/S11064-014-1391-2  0.344
2015 Adedara IA, Rosemberg DB, Souza DO, Kamdem JP, Farombi EO, Aschner M, Rocha JBT. Biochemical and behavioral deficits in the lobster cockroach Nauphoeta cinerea model of methylmercury exposure Toxicology Research. 4: 442-451. DOI: 10.1039/C4Tx00231H  0.348
2015 Fagundez DdA, Câmara DF, Salgueiro WG, Noremberg S, Puntel RL, Piccoli JE, Garcia SC, Rocha JBTd, Aschner M, Ávila DS. Behavioral and dopaminergic damage induced by acute iron toxicity in Caenorhabditis elegans Toxicology Research. 4: 878-884. DOI: 10.1039/C4Tx00120F  0.315
2014 Martinez-Finley EJ, Aschner M. Recent Advances in Mercury Research Current Environmental Health Reports. 1: 163-171. PMID 28018837 DOI: 10.1007/S40572-014-0014-Z  0.367
2014 Vorhees CV, Graham DL, Amos-Kroohs RM, Braun AA, Grace CE, Schaefer TL, Skelton MR, Erikson KM, Aschner M, Williams MT. Effects of developmental manganese, stress, and the combination of both on monoamines, growth, and corticosterone. Toxicology Reports. 1: 1046-1061. PMID 25574457 DOI: 10.1016/J.Toxrep.2014.10.004  0.324
2014 Yuntao F, Chenjia G, Panpan Z, Wenjun Z, Suhua W, Guangwei X, Haifeng S, Jian L, Wanxin P, Yun F, Cai J, Aschner M, Rongzhu L. Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes. Archives of Toxicology. PMID 25488884 DOI: 10.1007/S00204-014-1425-1  0.332
2014 Andrade V, Mateus ML, Batoréu MC, Aschner M, Marreilha dos Santos AP. Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by a mixture of lead, arsenic and manganese. Neurotoxicology. 45: 168-77. PMID 25451970 DOI: 10.1016/J.Neuro.2014.10.009  0.352
2014 Kumar KK, Lowe EW, Aboud AA, Neely MD, Redha R, Bauer JA, Odak M, Weaver CD, Meiler J, Aschner M, Bowman AB. Cellular manganese content is developmentally regulated in human dopaminergic neurons. Scientific Reports. 4: 6801. PMID 25348053 DOI: 10.1038/Srep06801  0.411
2014 Leyva-Illades D, Chen P, Zogzas CE, Hutchens S, Mercado JM, Swaim CD, Morrisett RA, Bowman AB, Aschner M, Mukhopadhyay S. SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14079-95. PMID 25319704 DOI: 10.1523/Jneurosci.2329-14.2014  0.414
2014 Chen P, Parmalee N, Aschner M. Genetic factors and manganese-induced neurotoxicity. Frontiers in Genetics. 5: 265. PMID 25136353 DOI: 10.3389/Fgene.2014.00265  0.41
2014 Caito S, Zeng H, Aschner JL, Aschner M. Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS. Plos One. 9: e98161. PMID 24852575 DOI: 10.1371/Journal.Pone.0098161  0.355
2014 von Tobel JS, Antinori P, Zurich MG, Rosset R, Aschner M, Glück F, Scherl A, Monnet-Tschudi F. Repeated exposure to Ochratoxin A generates a neuroinflammatory response, characterized by neurodegenerative M1 microglial phenotype. Neurotoxicology. 44: 61-70. PMID 24792326 DOI: 10.1016/J.Neuro.2014.04.005  0.379
2014 Exil V, Ping L, Yu Y, Chakraborty S, Caito SW, Wells KS, Karki P, Lee E, Aschner M. Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures. Plos One. 9: e94753. PMID 24787138 DOI: 10.1371/Journal.Pone.0094753  0.439
2014 Andrade V, Mateus ML, Santos D, Aschner M, Batoreu MC, Santos APMd. Arsenic and Manganese Alter Lead Deposition in the Rat Biological Trace Element Research. 158: 384-391. PMID 24715659 DOI: 10.1007/S12011-014-9954-2  0.348
2014 Caito SW, Yu Y, Aschner M. Differential inflammatory response to acrylonitrile in rat primary astrocytes and microglia. Neurotoxicology. 42: 1-7. PMID 24631314 DOI: 10.1016/J.Neuro.2014.02.006  0.328
2014 da Silva Santos V, Bisen-Hersh E, Yu Y, Cabral IS, Nardini V, Culbreth M, Teixeira da Rocha JB, Barbosa F, Aschner M. Anthocyanin-rich açaí (Euterpe oleracea Mart.) extract attenuates manganese-induced oxidative stress in rat primary astrocyte cultures. Journal of Toxicology and Environmental Health. Part A. 77: 390-404. PMID 24617543 DOI: 10.1080/15287394.2014.880392  0.321
2014 Bowman AB, Aschner M. Considerations on manganese (Mn) treatments for in vitro studies. Neurotoxicology. 41: 141-2. PMID 24509086 DOI: 10.1016/J.Neuro.2014.01.010  0.417
2014 Brinkhaus SG, Bornhorst J, Chakraborty S, Wehe CA, Niehaus R, Reifschneider O, Aschner M, Karst U. Elemental bioimaging of manganese uptake in C. elegans. Metallomics : Integrated Biometal Science. 6: 617-21. PMID 24481269 DOI: 10.1039/C3Mt00334E  0.313
2014 Karki P, Webb A, Smith K, Johnson J, Lee K, Son DS, Aschner M, Lee E. Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. Molecular and Cellular Biology. 34: 1280-9. PMID 24469401 DOI: 10.1128/Mcb.01176-13  0.38
2014 Bornhorst J, Chakraborty S, Meyer S, Lohren H, Brinkhaus SG, Knight AL, Caldwell KA, Caldwell GA, Karst U, Schwerdtle T, Bowman A, Aschner M. The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans. Metallomics : Integrated Biometal Science. 6: 476-90. PMID 24452053 DOI: 10.1039/C3Mt00325F  0.378
2014 Wollenhaupt SG, Soares AT, Salgueiro WG, Noremberg S, Reis G, Viana C, Gubert P, Soares FA, Affeldt RF, Lüdtke DS, Santos FW, Denardin CC, Aschner M, Avila DS. Seleno- and telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16/FOXO pathway. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 64: 192-9. PMID 24296137 DOI: 10.1016/J.Fct.2013.11.030  0.423
2014 López-Granero C, Cardona D, Giménez E, Lozano R, Barril J, Aschner M, Sánchez-Santed F, Cañadas F. Comparative study on short- and long-term behavioral consequences of organophosphate exposure: relationship to AChE mRNA expression. Neurotoxicology. 40: 57-64. PMID 24291005 DOI: 10.1016/J.Neuro.2013.11.004  0.304
2014 Bisen-Hersh EB, Farina M, Barbosa F, Rocha JB, Aschner M. Behavioral effects of developmental methylmercury drinking water exposure in rodents. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 28: 117-24. PMID 24210169 DOI: 10.1016/J.Jtemb.2013.09.008  0.331
2014 Santos D, Batoreu C, Mateus L, Marreilha Dos Santos AP, Aschner M. Manganese in human parenteral nutrition: considerations for toxicity and biomonitoring. Neurotoxicology. 43: 36-45. PMID 24184781 DOI: 10.1016/J.Neuro.2013.10.003  0.377
2014 Aschner M. Unmasking silent neurotoxicity following developmental exposure to methylmercury Neurotoxicology and Teratology. 43: 80. DOI: 10.1016/J.Ntt.2014.04.016  0.317
2013 Karki P, Lee E, Aschner M. Manganese neurotoxicity: a focus on glutamate transporters. Annals of Occupational and Environmental Medicine. 25: 4. PMID 24472696 DOI: 10.1186/2052-4374-25-4  0.437
2013 Avila DS, Puntel RL, Aschner M. Manganese in health and disease. Metal Ions in Life Sciences. 13: 199-227. PMID 24470093 DOI: 10.1007/978-94-007-7500-8_7  0.384
2013 Dalla Corte CL, Wagner C, Sudati JH, Comparsi B, Leite GO, Busanello A, Soares FA, Aschner M, Rocha JB. Effects of diphenyl diselenide on methylmercury toxicity in rats. Biomed Research International. 2013: 983821. PMID 24459674 DOI: 10.1155/2013/983821  0.325
2013 Peres TV, Pedro DZ, de Cordova FM, Lopes MW, Gonçalves FM, Mendes-de-Aguiar CB, Walz R, Farina M, Aschner M, Leal RB. In vitro manganese exposure disrupts MAPK signaling pathways in striatal and hippocampal slices from immature rats. Biomed Research International. 2013: 769295. PMID 24324973 DOI: 10.1155/2013/769295  0.391
2013 Chakraborty S, Bornhorst J, Nguyen TT, Aschner M. Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegans. International Journal of Molecular Sciences. 14: 23103-28. PMID 24284401 DOI: 10.3390/Ijms141123103  0.337
2013 Martinez-Finley EJ, Caito S, Slaughter JC, Aschner M. The Role of skn-1 in methylmercury-induced latent dopaminergic neurodegeneration. Neurochemical Research. 38: 2650-60. PMID 24194349 DOI: 10.1016/J.Ntt.2015.04.132  0.417
2013 Karki P, Webb A, Smith K, Lee K, Son DS, Aschner M, Lee E. cAMP response element-binding protein (CREB) and nuclear factor κB mediate the tamoxifen-induced up-regulation of glutamate transporter 1 (GLT-1) in rat astrocytes. The Journal of Biological Chemistry. 288: 28975-86. PMID 23955341 DOI: 10.1074/Jbc.M113.483826  0.319
2013 Caito SW, Valentine WM, Aschner M. Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-diethylthiocarbamate (MeDETC) in Caenorhabditis elegans. Journal of Neurochemistry. 127: 837-51. PMID 23786526 DOI: 10.1111/Jnc.12349  0.34
2013 Andrade V, Mateus ML, Batoréu MC, Aschner M, dos Santos AP. Urinary delta-ALA: a potential biomarker of exposure and neurotoxic effect in rats co-treated with a mixture of lead, arsenic and manganese. Neurotoxicology. 38: 33-41. PMID 23764341 DOI: 10.1016/J.Neuro.2013.06.003  0.388
2013 Chen P, Martinez-Finley EJ, Bornhorst J, Chakraborty S, Aschner M. Metal-induced neurodegeneration in C. elegans. Frontiers in Aging Neuroscience. 5: 18. PMID 23730287 DOI: 10.3389/Fnagi.2013.00018  0.333
2013 Zimmermann LT, Santos DB, Naime AA, Leal RB, Dórea JG, Barbosa F, Aschner M, Rocha JB, Farina M. Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes uptake. Neurotoxicology. 38: 1-8. PMID 23727015 DOI: 10.1016/J.Neuro.2013.05.015  0.361
2013 Caito SW, Zhang Y, Aschner M. Involvement of AAT transporters in methylmercury toxicity in Caenorhabditis elegans. Biochemical and Biophysical Research Communications. 435: 546-50. PMID 23669041 DOI: 10.1016/J.Bbrc.2013.04.090  0.315
2013 Caito S, Yu Y, Aschner M. Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia. Neurotoxicology. 37: 93-9. PMID 23628792 DOI: 10.1016/J.Neuro.2013.04.007  0.371
2013 Martinez-Finley EJ, Chakraborty S, Slaughter JC, Aschner M. Early-life exposure to methylmercury in wildtype and pdr-1/parkin knockout C. elegans. Neurochemical Research. 38: 1543-52. PMID 23609499 DOI: 10.1007/S11064-013-1054-8  0.372
2013 Zhang J, Cao R, Cai T, Aschner M, Zhao F, Yao T, Chen Y, Cao Z, Luo W, Chen J. The role of autophagy dysregulation in manganese-induced dopaminergic neurodegeneration. Neurotoxicity Research. 24: 478-90. PMID 23604964 DOI: 10.1007/S12640-013-9392-5  0.408
2013 Roth J, Ponzoni S, Aschner M. Manganese homeostasis and transport. Metal Ions in Life Sciences. 12: 169-201. PMID 23595673 DOI: 10.1007/978-94-007-5561-1_6  0.332
2013 Sidoryk-Wegrzynowicz M, Aschner M. Role of astrocytes in manganese mediated neurotoxicity. Bmc Pharmacology & Toxicology. 14: 23. PMID 23594835 DOI: 10.1186/2050-6511-14-23  0.327
2013 Zhang Y, Lu R, Liu W, Wu Y, Qian H, Zhao X, Wang S, Xing G, Yu F, Aschner M. Hormetic effects of acute methylmercury exposure on grp78 expression in rat brain cortex. Dose-Response : a Publication of International Hormesis Society. 11: 109-20. PMID 23549286 DOI: 10.2203/Dose-Response.11-055.Rongzhu  0.339
2013 Maitre NL, Aschner JL, Aschner M. Manganese neurotoxicity may underlie the association between early life iron deficiency and impaired spatial cognition in neonatal piglets. The Journal of Nutrition. 143: 548. PMID 23515251 DOI: 10.3945/Jn.112.173377  0.342
2013 Martinez-Finley EJ, Gavin CE, Aschner M, Gunter TE. Manganese neurotoxicity and the role of reactive oxygen species. Free Radical Biology & Medicine. 62: 65-75. PMID 23395780 DOI: 10.1016/J.Freeradbiomed.2013.01.032  0.349
2013 Cordova FM, Aguiar AS, Peres TV, Lopes MW, Gonçalves FM, Pedro DZ, Lopes SC, Pilati C, Prediger RD, Farina M, Erikson KM, Aschner M, Leal RB. Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox. Archives of Toxicology. 87: 1231-44. PMID 23385959 DOI: 10.1007/S00204-013-1017-5  0.416
2013 Sidoryk-Wegrzynowicz M, Aschner M. Manganese toxicity in the central nervous system: The glutamine/glutamate-γ-aminobutyric acid cycle Journal of Internal Medicine. 273: 466-477. PMID 23360507 DOI: 10.1111/Joim.12040  0.382
2013 DeWitt MR, Chen P, Aschner M. Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations. Biochemical and Biophysical Research Communications. 432: 1-4. PMID 23357421 DOI: 10.1016/J.Bbrc.2013.01.058  0.357
2013 Santos D, Batoreu MC, Aschner M, Marreilha dos Santos AP. Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity. Biological Trace Element Research. 152: 113-6. PMID 23315311 DOI: 10.1007/S12011-012-9597-0  0.403
2013 Stephenson AP, Schneider JA, Nelson BC, Atha DH, Jain A, Soliman KF, Aschner M, Mazzio E, Renee Reams R. Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: attenuation of thymine base lesions by glutathione and N-acetylcysteine. Toxicology Letters. 218: 299-307. PMID 23296100 DOI: 10.1016/J.Toxlet.2012.12.024  0.435
2013 Farina M, Avila DS, da Rocha JB, Aschner M. Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury. Neurochemistry International. 62: 575-94. PMID 23266600 DOI: 10.1016/J.Neuint.2012.12.006  0.389
2013 Gunter TE, Gerstner B, Gunter KK, Malecki J, Gelein R, Valentine WM, Aschner M, Yule DI. Manganese transport via the transferrin mechanism. Neurotoxicology. 34: 118-27. PMID 23146871 DOI: 10.1016/J.Neuro.2012.10.018  0.319
2013 Lee E, Sidoryk-Wegrzynowicz M, Farina M, Rocha JB, Aschner M. Estrogen attenuates manganese-induced glutamate transporter impairment in rat primary astrocytes. Neurotoxicity Research. 23: 124-30. PMID 22878846 DOI: 10.1007/S12640-012-9347-2  0.331
2012 Fretham SJB, Caito S, Martinez-Finley EJ, Aschner M. Mechanisms and modifiers of methylmercury-induced neurotoxicity Toxicology Research. 1: 32-38. PMID 27795823 DOI: 10.1039/C2Tx20010D  0.349
2012 Costa LG, Aschner M. An interview with Lucio G. Costa and Michael Aschner, section editors for toxicology. Bmc Pharmacology & Toxicology. 13: 16. PMID 23153341 DOI: 10.1186/2050-6511-13-16  0.327
2012 Santos D, Batoreu MC, Almeida I, Ramos R, Sidoryk-Wegrzynowicz M, Aschner M, Santos APMd. Manganese alters rat brain amino acids levels Biological Trace Element Research. 150: 337-341. PMID 22971893 DOI: 10.1007/S12011-012-9504-8  0.338
2012 Moreira EL, Oliveira Jd, Dutra MF, Santos DB, Gonçalves CA, Goldfeder EM, Bem AFd, Prediger RD, Aschner M, Farina M. Does Methylmercury-Induced Hypercholesterolemia Play a Causal Role in Its Neurotoxicity and Cardiovascular Disease? Toxicological Sciences. 130: 373-382. PMID 22903822 DOI: 10.1093/Toxsci/Kfs252  0.344
2012 Comparsi B, Meinerz DF, Franco JL, Posser T, Prestes AdS, Stefanello ST, Santos DBd, Wagner C, Farina M, Aschner M, Dafre AL, Rocha JBT. Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure. Molecular and Cellular Biochemistry. 370: 173-182. PMID 22886391 DOI: 10.1007/S11010-012-1408-6  0.357
2012 Ni M, Li X, Rocha JB, Farina M, Aschner M. Glia and methylmercury neurotoxicity. Journal of Toxicology and Environmental Health. Part A. 75: 1091-101. PMID 22852858 DOI: 10.1080/15287394.2012.697840  0.339
2012 Sidoryk-Wegrzynowicz M, Lee E, Aschner M. Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover. Journal of Neurochemistry. 122: 856-67. PMID 22708868 DOI: 10.1111/J.1471-4159.2012.07835.X  0.335
2012 Lee E, Sidoryk-Wêgrzynowicz M, Wang N, Webb A, Son DS, Lee K, Aschner M. GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes. The Journal of Biological Chemistry. 287: 26817-28. PMID 22645130 DOI: 10.1074/Jbc.M112.341867  0.326
2012 Aschner M. Considerations on methylmercury (MeHg) treatments in in vitro studies Neurotoxicology. 33: 512-513. PMID 22608940 DOI: 10.1016/J.Neuro.2012.05.002  0.301
2012 Chakraborty S, Aschner M. Altered manganese homeostasis: Implications for BLI-3-dependent dopaminergic neurodegeneration and SKN-1 protection in C. elegans Journal of Trace Elements in Medicine and Biology. 26: 183-187. PMID 22591558 DOI: 10.1016/J.Jtemb.2012.03.011  0.369
2012 Avila DS, Somlyai G, Somlyai I, Aschner M. Anti-aging effects of deuterium depletion on Mn-induced toxicity in a C. elegans model. Toxicology Letters. 211: 319-24. PMID 22561170 DOI: 10.1016/J.Toxlet.2012.04.014  0.343
2012 Dopp E, Bhattacharya S, Hirner AV, Aschner M, Schwerdtle T. Toxicity of Organometal(loids) Journal of Toxicology. 2012: 358484-358484. PMID 22523485 DOI: 10.1155/2012/358484  0.338
2012 Caito S, Fretham S, Martinez-Finley E, Chakraborty S, Avila D, Chen P, Aschner M. Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans. Frontiers in Genetics. 3: 52. PMID 22514555 DOI: 10.3389/Fgene.2012.00052  0.32
2012 Lee E, Sidoryk-Wegrzynowicz M, Yin Z, Webb A, Son DS, Aschner M. Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes. Glia. 60: 1024-36. PMID 22488924 DOI: 10.1002/Glia.22329  0.309
2012 Cordova FM, Aguiar AS, Peres TV, Lopes MW, Gonçalves FM, Remor AP, Lopes SC, Pilati C, Latini AS, Prediger RD, Erikson KM, Aschner M, Leal RB. In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function. Plos One. 7: e33057. PMID 22427945 DOI: 10.1371/Journal.Pone.0033057  0.399
2012 Avila DS, Benedetto A, Au C, Manarin F, Erikson K, Soares FA, Rocha JB, Aschner M. Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress. Free Radical Biology & Medicine. 52: 1903-10. PMID 22406322 DOI: 10.1016/J.Freeradbiomed.2012.02.044  0.367
2012 Madison JL, Wegrzynowicz M, Aschner M, Bowman AB. Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism. Plos One. 7: e31024. PMID 22363539 DOI: 10.1371/Journal.Pone.0031024  0.337
2012 SkowroÅ„ska M, ZieliÅ„ska M, Wójcik-Stanaszek L, Ruszkiewicz J, Milatovic D, Aschner M, Albrecht J. Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases. Journal of Neurochemistry. 121: 125-34. PMID 22260250 DOI: 10.1111/J.1471-4159.2012.07669.X  0.327
2012 Lee E, Yin Z, Sidoryk-Węgrzynowicz M, Jiang H, Aschner M. 15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes. Free Radical Biology & Medicine. 52: 1067-74. PMID 22245093 DOI: 10.1016/J.Freeradbiomed.2011.12.016  0.327
2012 Racette BA, Aschner M, Guilarte TR, Dydak U, Criswell SR, Zheng W. Pathophysiology of manganese-associated neurotoxicity. Neurotoxicology. 33: 881-6. PMID 22202748 DOI: 10.1016/J.Neuro.2011.12.010  0.361
2012 Wormser U, Brodsky B, Milatovic D, Finkelstein Y, Farina M, Rocha JB, Aschner M. Protective effect of a novel peptide against methylmercury-induced toxicity in rat primary astrocytes. Neurotoxicology. 33: 763-768. PMID 22186600 DOI: 10.1016/J.Neuro.2011.12.004  0.375
2012 Santos AP, Lucas RL, Andrade V, Mateus ML, Milatovic D, Aschner M, Batoreu MC. Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity. Toxicology and Applied Pharmacology. 258: 394-402. PMID 22178737 DOI: 10.1016/J.Taap.2011.12.003  0.389
2012 Santos D, Milatovic D, Andrade V, Batoreu MC, Aschner M, Santos APMd. The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain Toxicology. 292: 90-98. PMID 22154916 DOI: 10.1016/J.Tox.2011.11.017  0.377
2012 Martins EN, Pessano NTC, Leal L, Roos DH, Folmer V, Puntel GO, Rocha JBT, Aschner M, Ávila DS, Puntel RL. Protective effect of Melissa officinalis aqueous extract against Mn-induced oxidative stress in chronically exposed mice. Brain Research Bulletin. 87: 74-79. PMID 22020131 DOI: 10.1016/J.Brainresbull.2011.10.003  0.329
2012 Li Z, Chadalapaka G, Ramesh A, Khoshbouei H, Maguire M, Safe S, Rhoades RE, Clark R, Jules G, McCallister M, Aschner M, Hood DB. PAH particles perturb prenatal processes and phenotypes: protection from deficits in object discrimination afforded by dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 233-47. PMID 21987461 DOI: 10.1093/Toxsci/Kfr261  0.338
2012 Avila D, Helmcke K, Aschner M. The Caenorhabiditis elegans model as a reliable tool in neurotoxicology. Human & Experimental Toxicology. 31: 236-43. PMID 21148196 DOI: 10.1177/0960327110392084  0.316
2012 Ophir A, Doitsch E, Wormser U, Aschner M, Richter ED, Finkelstein Y. P-074: Exposure-Effect Gradient in Two Generations of Exposure to Pesticides Epidemiology. 23: 1. DOI: 10.1097/01.Ede.0000417081.59206.77  0.308
2012 Finkelstein Y, Ophir A, Doitsch E, Aschner M, Wormser U, Richter ED. S-117: Exposure-Effect Gradient in the Neurobehavior of Schoolchildren Endemically Exposed to Pesticides Epidemiology. 23: 1. DOI: 10.1097/01.Ede.0000416970.23835.64  0.311
2012 Corte CLD, Soares FAA, Aschner M, Rocha JBT. Diphenyl diselenide prevents methylmercury-induced mitochondrial dysfunction in rat liver slices Tetrahedron. 68: 10437-10443. DOI: 10.1016/J.Tet.2012.09.025  0.318
2011 Bowman AB, Kwakye GF, Herrero Hernández E, Aschner M. Role of manganese in neurodegenerative diseases. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 25: 191-203. PMID 21963226 DOI: 10.1016/J.Jtemb.2011.08.144  0.352
2011 Kaur P, Aschner M, Syversen T. Biochemical factors modulating cellular neurotoxicity of methylmercury. Journal of Toxicology. 2011: 721987-721987. PMID 21941541 DOI: 10.1155/2011/721987  0.356
2011 Aschner M. Volume measurements in cultured primary astrocytes Methods in Molecular Biology. 758: 391-402. PMID 21815080 DOI: 10.1007/978-1-61779-170-3_26  0.317
2011 Sidoryk-Wegrzynowicz M, Lee E, Mingwei N, Aschner M. Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway. Glia. 59: 1732-43. PMID 21812036 DOI: 10.1002/Glia.21219  0.367
2011 Owens SE, Summar ML, Ryckman KK, Haines JL, Reiss S, Summar SR, Aschner M. Lack of association between autism and four heavy metal regulatory genes. Neurotoxicology. 32: 769-75. PMID 21798283 DOI: 10.1016/J.Neuro.2011.07.003  0.301
2011 Milatovic D, Gupta RC, Yu Y, Zaja-Milatovic S, Aschner M. Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury. Toxicology and Applied Pharmacology. 256: 219-26. PMID 21684300 DOI: 10.1016/J.Taap.2011.06.001  0.373
2011 Madison JL, Wegrzynowicz M, Aschner M, Bowman AB. Gender and manganese exposure interactions on mouse striatal neuron morphology. Neurotoxicology. 32: 896-906. PMID 21641932 DOI: 10.1016/J.Neuro.2011.05.007  0.357
2011 Farina M, Aschner M, Rocha JBT. Oxidative stress in MeHg-induced neurotoxicity Toxicology and Applied Pharmacology. 256: 405-417. PMID 21601588 DOI: 10.1016/J.Taap.2011.05.001  0.356
2011 Milatovic D, Montine TJ, Aschner M. Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity. Neurotoxicology. 32: 312-9. PMID 21376752 DOI: 10.1016/J.Neuro.2011.02.004  0.308
2011 Ni M, Li X, Yin Z, Sidoryk-Węgrzynowicz M, Jiang H, Farina M, Rocha JB, Syversen T, Aschner M. Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity. Glia. 59: 810-20. PMID 21351162 DOI: 10.1002/Glia.21153  0.363
2011 Yin Z, Lee E, Ni M, Jiang H, Milatovic D, Rongzhu L, Farina M, Rocha JB, Aschner M. Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen. Neurotoxicology. 32: 291-9. PMID 21300091 DOI: 10.1016/J.Neuro.2011.01.004  0.349
2011 Roos DH, Puntel RL, Farina M, Aschner M, Bohrer D, Rocha JBT, Barbosa NBdV. Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism. Toxicology and Applied Pharmacology. 252: 28-35. PMID 21276810 DOI: 10.1016/J.Taap.2011.01.010  0.339
2011 Santos APMd, Santos ML, Batoréu MC, Aschner M. Prolactin is a peripheral marker of manganese neurotoxicity Brain Research. 1382: 282-290. PMID 21262206 DOI: 10.1016/J.Brainres.2011.01.047  0.375
2011 Milatovic D, Jenkins JW, Hood JE, Yu Y, Rongzhu L, Aschner M. Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase. Neurotoxicology. 32: 578-85. PMID 21241737 DOI: 10.1016/J.Neuro.2011.01.001  0.334
2011 Fitsanakis VA, Zhang N, Avison MJ, Erikson KM, Gore JC, Aschner M. Changes in dietary iron exacerbate regional brain manganese accumulation as determined by magnetic resonance imaging. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 146-53. PMID 21177776 DOI: 10.1093/Toxsci/Kfq376  0.305
2011 Le TM, Jiang H, Cunningham GR, Magarik JA, Barge WS, Cato MC, Farina M, Rocha JB, Milatovic D, Lee E, Aschner M, Summar ML. γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo. Neurotoxicology. 32: 518-25. PMID 21159318 DOI: 10.1016/J.Neuro.2010.11.008  0.35
2011 Sidoryk-Wegrzynowicz M, Wegrzynowicz M, Lee E, Bowman AB, Aschner M. Role of astrocytes in brain function and disease. Toxicologic Pathology. 39: 115-23. PMID 21075920 DOI: 10.1177/0192623310385254  0.318
2011 Dydak U, Jiang YM, Long LL, Zhu H, Chen J, Li WM, Edden RA, Hu S, Fu X, Long Z, Mo XA, Meier D, Harezlak J, Aschner M, Murdoch JB, et al. In vivo measurement of brain GABA concentrations by magnetic resonance spectroscopy in smelters occupationally exposed to manganese. Environmental Health Perspectives. 119: 219-24. PMID 20876035 DOI: 10.1289/Ehp.1002192  0.307
2011 Meinerz DF, Sudati JH, dos Santos DB, Frediani A, Alberto EE, Allebrandt J, Franco JL, Barbosa NB, Aschner M, da Rocha JB. Evaluation of the biological effects of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate, a new telluroamino acid derivative of aspartic acid. Archives of Toxicology. 85: 43-9. PMID 20490464 DOI: 10.1007/S00204-010-0555-3  0.309
2011 Farina M, Rocha JBT, Aschner M. Mechanisms of methylmercury-induced neurotoxicity: Evidence from experimental studies Life Sciences. 89: 555-563. DOI: 10.1016/J.Lfs.2011.05.019  0.402
2010 Albrecht J, Sidoryk-WÄ™grzynowicz M, ZieliÅ„ska M, Aschner M. Roles of glutamine in neurotransmission. Neuron Glia Biology. 6: 263-76. PMID 22018046 DOI: 10.1017/S1740925X11000093  0.31
2010 Franco JL, Posser T, Missau F, Pizzolatti MG, Dos Santos AR, Souza DO, Aschner M, Rocha JB, Dafre AL, Farina M. Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction. Environmental Toxicology and Pharmacology. 30: 272-278. PMID 21127717 DOI: 10.1016/J.Etap.2010.07.003  0.336
2010 Ni M, Aschner M. Neonatal rat primary microglia: isolation, culturing, and selected applications. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 12.17. PMID 20960423 DOI: 10.1002/0471140856.Tx1217S43  0.312
2010 Sheng L, Ding X, Ferguson M, McCallister M, Rhoades R, Maguire M, Ramesh A, Aschner M, Campbell D, Levitt P, Hood DB. Prenatal polycyclic aromatic hydrocarbon exposure leads to behavioral deficits and downregulation of receptor tyrosine kinase, MET. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 625-34. PMID 20889680 DOI: 10.1093/Toxsci/Kfq304  0.314
2010 Aschner M, Onishchenko N, Ceccatelli S. Toxicology of alkylmercury compounds Metal Ions in Life Sciences. 7: 403-434. PMID 20877814 DOI: 10.1039/9781849730822-00403  0.34
2010 Benedetto A, Au C, Avila DS, Milatovic D, Aschner M. Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans. Plos Genetics. 6. PMID 20865164 DOI: 10.1371/Journal.Pgen.1001084  0.33
2010 Sidoryk-Wegrzynowicz M, Lee ES, Ni M, Aschner M. Manganese-induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin-mediated proteolytic system. Glia. 58: 1905-12. PMID 20737472 DOI: 10.1002/Glia.21060  0.358
2010 Helmcke KJ, Aschner M. Hormetic effect of methylmercury on Caenorhabditis elegans Toxicology and Applied Pharmacology. 248: 156-164. PMID 20691719 DOI: 10.1016/J.Taap.2010.07.023  0.371
2010 Kaur P, Evje L, Aschner M, Syversen T. The in vitro effects of Trolox on methylmercury-induced neurotoxicity. Toxicology. 276: 73-78. PMID 20637824 DOI: 10.1016/J.Tox.2010.07.006  0.357
2010 Finkelstein Y, Milatovic D, Lazarovici P, Ophir A, Richter ED, Aschner M, Lecht S, Marcinkiewicz C, Lelkes PI, Zaja-Milatovic S, Gupta RC, Brodsky B, Rosengarten A, Proscura E, Shapira E, et al. Peaceful use of disastrous neurotoxicants. Neurotoxicology. 31: 608-20. PMID 20620165 DOI: 10.1016/J.Neuro.2010.06.009  0.354
2010 Hood JE, Jenkins JW, Milatovic D, Rongzhu L, Aschner M. Mefloquine induces oxidative stress and neurodegeneration in primary rat cortical neurons. Neurotoxicology. 31: 518-23. PMID 20562019 DOI: 10.1016/J.Neuro.2010.05.005  0.315
2010 Williams BB, Kwakye GF, Wegrzynowicz M, Li D, Aschner M, Erikson KM, Bowman AB. Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 169-79. PMID 20547568 DOI: 10.1093/Toxsci/Kfq174  0.327
2010 Ni M, Li X, Yin Z, Jiang H, Sidoryk-Wegrzynowicz M, Milatovic D, Cai J, Aschner M. Methylmercury induces acute oxidative stress, altering Nrf2 protein level in primary microglial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 590-603. PMID 20421342 DOI: 10.1093/Toxsci/Kfq126  0.396
2010 Aschner M, Levin ED, Suñol C, Olopade JO, Helmcke KJ, Avila DS, Sledge D, Ali RH, Upchurch L, Donerly S, Linney E, Forsby A, Ponnuru P, Connor JR. Gene-environment interactions: neurodegeneration in non-mammals and mammals. Neurotoxicology. 31: 582-8. PMID 20359493 DOI: 10.1016/J.Neuro.2010.03.008  0.333
2010 Santos APMD, Milatovic D, Au C, Yin Z, Batoreu MCC, Aschner M. Rat brain endothelial cells are a target of manganese toxicity. Brain Research. 1326: 152-161. PMID 20170646 DOI: 10.1016/J.Brainres.2010.02.016  0.383
2010 Avila DS, Colle D, Gubert P, Palma AS, Puntel G, Manarin F, Noremberg S, Nascimento PC, Aschner M, Rocha JB, Soares FA. A possible neuroprotective action of a vinylic telluride against Mn-induced neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 194-201. PMID 20133376 DOI: 10.1093/Toxsci/Kfq036  0.324
2010 Suhua W, Rongzhu L, Wenrong X, Guangwei X, Xiaowu Z, Shizhong W, Ye Z, Fangan H, Aschner M. Induction or inhibition of cytochrome P450 2E1 modifies the acute toxicity of acrylonitrile in rats: biochemical evidence. Archives of Toxicology. 84: 461-9. PMID 20127315 DOI: 10.1007/S00204-010-0519-7  0.301
2010 Williams JM, Milatovic D, Gore JC, Aschner M, Avison MJ. Chronic exposure to manganese alters brain responses to amphetamine: a pharmacological magnetic resonance imaging study. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 310-22. PMID 20061340 DOI: 10.1093/Toxsci/Kfq002  0.326
2010 Yin Z, Jiang H, Lee ES, Ni M, Erikson KM, Milatovic D, Bowman AB, Aschner M. Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation. Journal of Neurochemistry. 112: 1190-8. PMID 20002294 DOI: 10.1111/J.1471-4159.2009.06534.X  0.395
2010 Fitsanakis VA, Zhang N, Garcia S, Aschner M. Manganese (Mn) and iron (Fe): interdependency of transport and regulation. Neurotoxicity Research. 18: 124-31. PMID 19921534 DOI: 10.1007/S12640-009-9130-1  0.324
2010 Guangwei X, Rongzhu L, Wenrong X, Suhua W, Xiaowu Z, Shizhong W, Ye Z, Aschner M, Kulkarni SK, Bishnoi M. Curcumin pretreatment protects against acute acrylonitrile-induced oxidative damage in rats. Toxicology. 267: 140-6. PMID 19913070 DOI: 10.1016/J.Tox.2009.11.001  0.358
2010 Wagner C, Vargas AP, Roos DH, Morel AF, Farina M, Nogueira CW, Aschner M, Rocha JB. Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices. Archives of Toxicology. 84: 89-97. PMID 19902180 DOI: 10.1007/S00204-009-0482-3  0.376
2010 Williams BB, Li D, Wegrzynowicz M, Vadodaria BK, Anderson JG, Kwakye GF, Aschner M, Erikson KM, Bowman AB. Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure. Journal of Neurochemistry. 112: 227-37. PMID 19845833 DOI: 10.1111/J.1471-4159.2009.06445.X  0.371
2010 Aschner M, Ceccatelli S. Are neuropathological conditions relevant to ethylmercury exposure? Neurotoxicity Research. 18: 59-68. PMID 19756911 DOI: 10.1007/S12640-009-9113-2  0.329
2010 Santos APMD, Andrade V, Mateus ML, Aschner M, Batoréu MC. Occupational exposure of miners to manganese and lead—A preliminary study Toxicology Letters. 196. DOI: 10.1016/J.Toxlet.2010.03.292  0.308
2009 da Conceição Nascimento Pinheiro M, do Nascimento JLM, de Lima Silveira LC, da Rocha JBT, Aschner M. Mercury and Selenium - A Review on Aspects Related to the Health of Human Populations in the Amazon. Environmental Bioindicators. 4: 222-245. PMID 31485199 DOI: 10.1080/15555270903143440  0.361
2009 Aschner M, Jiang GCT. Toxicity studies on depleted uranium in primary rat cortical neurons and in caenorhabditis elegans: What have we learned? Journal of Toxicology and Environmental Health - Part B: Critical Reviews. 12: 525-539. PMID 20183532 DOI: 10.1080/10937400903358942  0.38
2009 Au C, Benedetto A, Anderson J, Labrousse A, Erikson K, Ewbank JJ, Aschner M. SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans. Plos One. 4: e7792. PMID 19924247 DOI: 10.1371/Journal.Pone.0007792  0.364
2009 Aschner M, Erikson KM, Herrero Hernández E, Hernández EH, Tjalkens R. Manganese and its role in Parkinson's disease: from transport to neuropathology. Neuromolecular Medicine. 11: 252-66. PMID 19657747 DOI: 10.1007/S12017-009-8083-0  0.392
2009 Jiang GC, Hughes S, Stürzenbaum SR, Evje L, Syversen T, Aschner M. Caenorhabditis elegans metallothioneins protect against toxicity induced by depleted uranium. Toxicological Sciences : An Official Journal of the Society of Toxicology. 111: 345-54. PMID 19617453 DOI: 10.1093/Toxsci/Kfp161  0.367
2009 Zaja-Milatovic S, Gupta RC, Aschner M, Milatovic D. Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist Toxicology and Applied Pharmacology. 240: 124-131. PMID 19615394 DOI: 10.1016/J.Taap.2009.07.006  0.342
2009 Milatovic D, Zaja-Milatovic S, Gupta RC, Yu Y, Aschner M. Oxidative damage and neurodegeneration in manganese-induced neurotoxicity. Toxicology and Applied Pharmacology. 240: 219-225. PMID 19607852 DOI: 10.1016/J.Taap.2009.07.004  0.387
2009 Santos DB, Schiar VP, Paixão MW, Meinerz DF, Nogueira CW, Aschner M, Rocha JB, Barbosa NB. Hemolytic and genotoxic evaluation of organochalcogens in human blood cells in vitro. Toxicology in Vitro : An International Journal Published in Association With Bibra. 23: 1195-204. PMID 19477262 DOI: 10.1016/J.Tiv.2009.05.010  0.308
2009 Rongzhu L, Suhua W, Guangwei X, Chunlan R, Fangan H, Suxian C, Zhengxian Z, Qiuwei Z, Aschner M. Effects of acrylonitrile on antioxidant status of different brain regions in rats. Neurochemistry International. 55: 552-557. PMID 19463879 DOI: 10.1016/J.Neuint.2009.05.009  0.323
2009 Stanwood GD, Leitch DB, Savchenko V, Wu J, Fitsanakis VA, Anderson DJ, Stankowski JN, Aschner M, McLaughlin B. Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia. Journal of Neurochemistry. 110: 378-89. PMID 19457100 DOI: 10.1111/J.1471-4159.2009.06145.X  0.386
2009 Sidoryk-Wegrzynowicz M, Lee E, Albrecht J, Aschner M. Manganese disrupts astrocyte glutamine transporter expression and function. Journal of Neurochemistry. 110: 822-30. PMID 19457077 DOI: 10.1111/J.1471-4159.2009.06172.X  0.356
2009 Lee ESY, Sidoryk M, Jiang H, Yin Z, Aschner M. Estrogen and tamoxifen reverse manganese‐induced glutamate transporter impairment in astrocytes Journal of Neurochemistry. 110: 530-544. PMID 19453300 DOI: 10.1111/J.1471-4159.2009.06105.X  0.342
2009 Yin Z, Albrecht J, Syversen T, Jiang H, Summar M, Rocha JB, Farina M, Aschner M. Comparison of alterations in amino acids content in cultured astrocytes or neurons exposed to methylmercury separately or in co-culture. Neurochemistry International. 55: 136-42. PMID 19428818 DOI: 10.1016/J.Neuint.2009.01.015  0.322
2009 Fitsanakis VA, Thompson KN, Deery SE, Milatovic D, Shihabi ZK, Erikson KM, Brown RW, Aschner M. A chronic iron-deficient/high-manganese diet in rodents results in increased brain oxidative stress and behavioral deficits in the morris water maze. Neurotoxicity Research. 15: 167-78. PMID 19384579 DOI: 10.1007/S12640-009-9017-1  0.336
2009 Lee ESY, Yin Z, Milatovic D, Jiang H, Aschner M. Estrogen and Tamoxifen Protect against Mn-Induced Toxicity in Rat Cortical Primary Cultures of Neurons and Astrocytes Toxicological Sciences. 110: 156-167. PMID 19383943 DOI: 10.1093/Toxsci/Kfp081  0.366
2009 Helmcke KJ, Syversen T, Miller DM, Aschner M. Characterization of the effects of methylmercury on Caenorhabditis elegans. Toxicology and Applied Pharmacology. 240: 265-72. PMID 19341752 DOI: 10.1016/J.Taap.2009.03.013  0.354
2009 Kaur P, Evje L, Aschner M, Syversen T. The in vitro effects of selenomethionine on methylmercury-induced neurotoxicity. Toxicology in Vitro. 23: 378-385. PMID 19168124 DOI: 10.1016/J.Tiv.2008.12.024  0.334
2009 Rongzhu L, Suhua W, Guangwei X, Chunlan R, Fangan H, Junjie J, Aschner M. Zinc, Copper, Iron, and Selenium Levels in Brain and Liver of Mice Exposed to Acrylonitrile Biological Trace Element Research. 130: 39-47. PMID 19165426 DOI: 10.1007/S12011-008-8310-9  0.304
2009 Roos DH, Puntel RL, Santos MM, Souza DO, Farina M, Nogueira CW, Aschner M, Burger ME, Barbosa NB, Rocha JB. Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system. Toxicology in Vitro : An International Journal Published in Association With Bibra. 23: 302-7. PMID 19162164 DOI: 10.1016/J.Tiv.2008.12.020  0.365
2009 Martins Rde P, Braga Hde C, da Silva AP, Dalmarco JB, de Bem AF, dos Santos AR, Dafre AL, Pizzolatti MG, Latini A, Aschner M, Farina M. Synergistic neurotoxicity induced by methylmercury and quercetin in mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 47: 645-9. PMID 19141311 DOI: 10.1016/J.Fct.2008.12.020  0.337
2009 Zhang N, Fitsanakis VA, Erikson KM, Aschner M, Avison MJ, Gore JC. A model for the analysis of competitive relaxation effects of manganese and iron in vivo. Nmr in Biomedicine. 22: 391-404. PMID 19137511 DOI: 10.1002/Nbm.1348  0.301
2009 de Freitas AS, Funck VR, Rotta Mdos S, Bohrer D, Mörschbächer V, Puntel RL, Nogueira CW, Farina M, Aschner M, Rocha JB. Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice. Brain Research Bulletin. 79: 77-84. PMID 19047014 DOI: 10.1016/J.Brainresbull.2008.11.001  0.339
2009 Wang L, Jiang H, Yin Z, Aschner M, Cai J. Methylmercury Toxicity and Nrf2-dependent Detoxification in Astrocytes Toxicological Sciences. 107: 135-143. PMID 18815141 DOI: 10.1093/Toxsci/Kfn201  0.383
2008 Ávila DS, Gubert P, Fachinetto R, Wagner C, Aschner M, Rocha JBT, Soares FAA. Involvement of striatal lipid peroxidation and inhibition of calcium influx into brain slices in neurobehavioral alterations in a rat model of short-term oral exposure to manganese. Neurotoxicology. 29: 1062-1068. PMID 18778733 DOI: 10.1016/J.Neuro.2008.08.004  0.407
2008 McCallister MM, Maguire M, Ramesh A, Aimin Q, Liu S, Khoshbouei H, Aschner M, Ebner FF, Hood DB. Prenatal exposure to benzo(a)pyrene impairs later-life cortical neuronal function. Neurotoxicology. 29: 846-54. PMID 18761371 DOI: 10.1016/J.Neuro.2008.07.008  0.329
2008 Santos APMd, Santos D, Au C, Milatovic D, Aschner M, Batoréu MCC. Antioxidants prevent the cytotoxicity of manganese in RBE4 cells Brain Research. 1236: 200-205. PMID 18725210 DOI: 10.1016/J.Brainres.2008.07.125  0.406
2008 Kaur P, Heggland I, Aschner M, Syversen T. Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures. Neurotoxicology. 29: 978-987. PMID 18619488 DOI: 10.1016/J.Neuro.2008.06.004  0.357
2008 Au C, Benedetto A, Aschner M. Manganese transport in eukaryotes : the role of DMT1 Neurotoxicology. 29: 569-576. PMID 18565586 DOI: 10.1016/J.Neuro.2008.04.022  0.377
2008 Kaur P, Schulz K, Heggland I, Aschner M, Syversen T. The use of fluorescence for detecting MeHg-induced ROS in cell cultures Toxicology in Vitro. 22: 1392-1398. PMID 18343630 DOI: 10.1016/J.Tiv.2008.01.017  0.319
2008 Erikson KM, Dorman DC, Lash LH, Aschner M. Duration of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity. Neurotoxicology. 29: 377-85. PMID 18314193 DOI: 10.1016/J.Neuro.2007.12.007  0.348
2008 Yin Z, Aschner JL, dos Santos AP, Aschner M. Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures Brain Research. 1203: 1-11. PMID 18313649 DOI: 10.1016/J.Brainres.2008.01.079  0.362
2008 West AK, Hidalgo J, Eddins D, Levin ED, Aschner M. Metallothionein in the central nervous system: Roles in protection, regeneration and cognition. Neurotoxicology. 29: 489-503. PMID 18313142 DOI: 10.1016/J.Neuro.2007.12.006  0.324
2008 Fitsanakis VA, Zhang N, Anderson JG, Erikson KM, Avison MJ, Gore JC, Aschner M. Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging. Toxicological Sciences : An Official Journal of the Society of Toxicology. 103: 116-24. PMID 18234737 DOI: 10.1093/Toxsci/Kfn019  0.32
2008 Aschner M, Syversen T, Souza DO, Rocha JB, Farina M. Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 40: 285-91. PMID 17334523 DOI: 10.1590/S0100-879X2007000300001  0.382
2007 Stringari J, Nunes AK, Franco JL, Bohrer D, Garcia SC, Dafre AL, Milatovic D, Souza DO, Rocha JB, Aschner M, Farina M. Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain. Toxicology and Applied Pharmacology. 227: 147-54. PMID 18023834 DOI: 10.1016/J.Taap.2007.10.010  0.397
2007 Finkelstein Y, Milatovic D, Aschner M. Modulation of cholinergic systems by manganese Neurotoxicology. 28: 1003-1014. PMID 17920128 DOI: 10.1016/J.Neuro.2007.08.006  0.315
2007 Kaur P, Schulz K, Aschner M, Syversen T. Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity. Toxicological Sciences. 100: 423-432. PMID 17728287 DOI: 10.1093/Toxsci/Kfm224  0.32
2007 Jiang GC, Tidwell K, McLaughlin BA, Cai J, Gupta RC, Milatovic D, Nass R, Aschner M. Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 553-65. PMID 17636247 DOI: 10.1093/Toxsci/Kfm171  0.37
2007 Fitsanakis VA, Piccola G, Marreilha dos Santos AP, Aschner JL, Aschner M. Putative proteins involved in manganese transport across the blood-brain barrier. Human & Experimental Toxicology. 26: 295-302. PMID 17615110 DOI: 10.1177/0960327107070496  0.345
2007 Brown LA, Khousbouei H, Goodwin JS, Irvin-Wilson CV, Ramesh A, Sheng L, McCallister MM, Jiang GC, Aschner M, Hood DB. Down-regulation of early ionotrophic glutamate receptor subunit developmental expression as a mechanism for observed plasticity deficits following gestational exposure to benzo(a)pyrene. Neurotoxicology. 28: 965-78. PMID 17606297 DOI: 10.1016/J.Neuro.2007.05.005  0.332
2007 Soldin OP, Aschner M. Effects of manganese on thyroid hormone homeostasis: Potential links Neurotoxicology. 28: 951-956. PMID 17576015 DOI: 10.1016/J.Neuro.2007.05.003  0.32
2007 Milatovic D, Yin Z, Gupta RC, Sidoryk M, Albrecht J, Aschner JL, Aschner M. Manganese induces oxidative impairment in cultured rat astrocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 198-205. PMID 17468184 DOI: 10.1093/Toxsci/Kfm095  0.391
2007 Aschner M, Guilarte TR, Schneider JS, Zheng W. Manganese: recent advances in understanding its transport and neurotoxicity. Toxicology and Applied Pharmacology. 221: 131-47. PMID 17466353 DOI: 10.1016/J.Taap.2007.03.001  0.317
2007 Erikson KM, Dorman DC, Lash LH, Aschner M. Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 459-66. PMID 17347134 DOI: 10.1093/Toxsci/Kfm044  0.324
2007 Gupta RC, Milatovic S, Dettbarn WD, Aschner M, Milatovic D. Neuronal oxidative injury and dendritic damage induced by carbofuran: protection by memantine. Toxicology and Applied Pharmacology. 219: 97-105. PMID 17188316 DOI: 10.1016/J.Taap.2006.10.028  0.328
2007 Yin Z, Milatovic D, Aschner JL, Syversen T, Rocha JB, Souza DO, Sidoryk M, Albrecht J, Aschner M. Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes. Brain Research. 1131: 1-10. PMID 17182013 DOI: 10.1016/J.Brainres.2006.10.070  0.388
2007 Kaur P, Aschner M, Syversen T. Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress Toxicology. 230: 164-177. PMID 17169475 DOI: 10.1016/J.Tox.2006.11.058  0.335
2007 Erikson KM, Thompson K, Aschner J, Aschner M. Manganese neurotoxicity: a focus on the neonate. Pharmacology & Therapeutics. 113: 369-77. PMID 17084903 DOI: 10.1016/J.Pharmthera.2006.09.002  0.37
2007 Garcia SJ, Gellein K, Syversen T, Aschner M. Iron deficient and manganese supplemented diets alter metals and transporters in the developing rat brain. Toxicological Sciences : An Official Journal of the Society of Toxicology. 95: 205-14. PMID 17060373 DOI: 10.1093/Toxsci/Kfl139  0.317
2007 Penkowa M, Hidalgo J, Aschner M. Immune and Inflammatory Responses in the Central Nervous System: Modulation by Astrocytes Neuroimmune Biology. 6. DOI: 10.1016/S1567-7443(07)10013-2  0.313
2006 Aschner M, Dorman DC. Manganese: pharmacokinetics and molecular mechanisms of brain uptake. Toxicological Reviews. 25: 147-54. PMID 17192121 DOI: 10.2165/00139709-200625030-00002  0.387
2006 Aschner M, Syversen T, Souza DO, Rocha JBT. Metallothioneins: mercury species-specific induction and their potential role in attenuating neurotoxicity. Experimental Biology and Medicine. 231: 1468-1473. PMID 17018868 DOI: 10.1177/153537020623100904  0.336
2006 Erikson KM, Dorman DC, Fitsanakis V, Lash LH, Aschner M. Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese. Biological Trace Element Research. 111: 199-215. PMID 16943606 DOI: 10.1385/Bter:111:1:199  0.364
2006 Fitsanakis VA, Erikson KM, Garcia SJ, Evje L, Syversen T, Aschner M. Brain accumulation of depleted uranium in rats following 3- or 6-month treatment with implanted depleted uranium pellets. Biological Trace Element Research. 111: 185-97. PMID 16943605 DOI: 10.1385/Bter:111:1:185  0.301
2006 Aschner M. Manganese as a potential confounder of serum prolactin [1] Environmental Health Perspectives. 114. PMID 16882508 DOI: 10.1289/Ehp.114-A458A  0.304
2006 Walker SJ, Segal J, Aschner M. Cultured lymphocytes from autistic children and non-autistic siblings up-regulate heat shock protein RNA in response to thimerosal challenge Neurotoxicology. 27: 685-692. PMID 16870260 DOI: 10.1016/J.Neuro.2006.06.003  0.326
2006 Taylor MD, Erikson KM, Dobson AW, Fitsanakis VA, Dorman DC, Aschner M. Effects of inhaled manganese on biomarkers of oxidative stress in the rat brain. Neurotoxicology. 27: 788-97. PMID 16842851 DOI: 10.1016/J.Neuro.2006.05.006  0.38
2006 Gunter TE, Gavin CE, Aschner M, Gunter KK. Speciation of manganese in cells and mitochondria: A search for the proximal cause of manganese neurotoxicity Neurotoxicology. 27: 765-776. PMID 16765446 DOI: 10.1016/J.Neuro.2006.05.002  0.342
2006 Garcia SJ, Gellein K, Syversen T, Aschner M. A manganese-enhanced diet alters brain metals and transporters in the developing rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 92: 516-25. PMID 16705042 DOI: 10.1093/Toxsci/Kfl017  0.353
2006 Dobson AW, Lack AK, Erikson KM, Aschner M. Depleted uranium is not toxic to rat brain endothelial (RBE4) cells. Biological Trace Element Research. 110: 61-72. PMID 16679548 DOI: 10.1385/Bter:110:1:61  0.317
2006 Jiang GCT, Aschner M. Neurotoxicity of depleted uranium: Reasons for increased concern Biological Trace Element Research. 110: 1-17. PMID 16679544 DOI: 10.1385/Bter:110:1:1  0.317
2006 Mutkus L, Aschner JL, Syversen T, Shanker G, Sonnewald U, Aschner M. Mercuric chloride inhibits the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells. Biological Trace Element Research. 109: 267-280. PMID 16632895 DOI: 10.1385/Bter:109:3:267  0.316
2006 Fitsanakis VA, Zhang N, Avison MJ, Gore JC, Aschner JL, Aschner M. The use of magnetic resonance imaging (MRI) in the study of manganese neurotoxicity. Neurotoxicology. 27: 798-806. PMID 16620989 DOI: 10.1016/J.Neuro.2006.03.001  0.334
2006 Milatovic D, Gupta RC, Aschner M. Anticholinesterase toxicity and oxidative stress Thescientificworldjournal. 6: 295-310. PMID 16518518 DOI: 10.1100/Tsw.2006.38  0.337
2006 Fitsanakis VA, Au C, Erikson KM, Aschner M. The effects of manganese on glutamate, dopamine and gamma-aminobutyric acid regulation. Neurochemistry International. 48: 426-33. PMID 16513220 DOI: 10.1016/J.Neuint.2005.10.012  0.347
2006 Kaur P, Aschner M, Syversen T. Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes Neurotoxicology. 27: 492-500. PMID 16513172 DOI: 10.1016/J.Neuro.2006.01.010  0.386
2006 Aschner M. The transport of manganese across the blood-brain barrier Neurotoxicology. 27: 311-314. PMID 16460806 DOI: 10.1016/J.Neuro.2005.09.002  0.313
2006 Aschner M, Lukey B, Tremblay A. The Manganese Health Research Program (MHRP): status report and future research needs and directions. Neurotoxicology. 27: 733-736. PMID 16325914 DOI: 10.1016/J.Neuro.2005.10.005  0.309
2006 Gunter KK, Aschner M, Miller LM, Eliseev R, Salter J, Anderson K, Gunter TE. Determining the oxidation states of manganese in NT2 cells and cultured astrocytes. Neurobiology of Aging. 27: 1816-26. PMID 16290323 DOI: 10.1016/J.Neurobiolaging.2005.10.003  0.335
2006 Fitsanakis VA, Piccola G, Aschner JL, Aschner M. Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model of the blood-brain barrier. Neurotoxicology. 27: 60-70. PMID 16169084 DOI: 10.1016/J.Neuro.2005.06.004  0.339
2006 Erikson KM, Aschner M. Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primarily by divalent metal transporter. Neurotoxicology. 27: 125-30. PMID 16140386 DOI: 10.1016/J.Neuro.2005.07.003  0.347
2006 Aschner M, Sonnewald U, Tan KH. Astrocyte modulation of neurotoxic injury. Brain Pathology. 12: 475-481. PMID 12408234 DOI: 10.1111/J.1750-3639.2002.Tb00465.X  0.319
2005 Erikson KM, John CE, Jones SR, Aschner M. Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter. Environmental Toxicology and Pharmacology. 20: 390-4. PMID 21783617 DOI: 10.1016/J.Etap.2005.03.009  0.329
2005 Erikson KM, Syversen T, Aschner JL, Aschner M. Interactions between excessive manganese exposures and dietary iron-deficiency in neurodegeneration. Environmental Toxicology and Pharmacology. 19: 415-21. PMID 21783506 DOI: 10.1016/J.Etap.2004.12.053  0.34
2005 Aschner M, West AK. The role of MT in neurological disorders Journal of Alzheimer's Disease. 8: 139-145. PMID 16308482 DOI: 10.3233/Jad-2005-8206  0.328
2005 Mutkus L, Aschner JL, Syversen T, Aschner M. Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells Biological Trace Element Research. 107: 231-245. PMID 16286679 DOI: 10.1385/Bter:107:3:231  0.35
2005 Mutkus L, Aschner JL, Fitsanakis V, Aschner M. The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by manganese Biological Trace Element Research. 107: 221-230. PMID 16286678 DOI: 10.1385/Bter:107:3:221  0.335
2005 Aschner M, Wu Q, Friedman MA. Effects of acrylamide on primary neonatal rat astrocyte functions Annals of the New York Academy of Sciences. 1053: 444-454. PMID 16179551 DOI: 10.1196/Annals.1344.039  0.323
2005 Aschner JL, Aschner M. Nutritional aspects of manganese homeostasis Molecular Aspects of Medicine. 26: 353-362. PMID 16099026 DOI: 10.1016/J.Mam.2005.07.003  0.342
2005 Gunter KK, Aschner M, Miller LM, Eliseev R, Salter J, Anderson K, Hammond S, Gunter TE. Determining the oxidation states of manganese in PC12 and nerve growth factor-induced PC12 cells. Free Radical Biology & Medicine. 39: 164-81. PMID 15964508 DOI: 10.1016/J.Freeradbiomed.2005.03.004  0.353
2005 Morken TS, Sonnewald U, Aschner M, Syversen T. Effects of methylmercury on primary brain cells in mono- and co-culture. Toxicological Sciences. 87: 169-175. PMID 15958655 DOI: 10.1093/Toxsci/Kfi227  0.329
2005 Shanker G, Syversen T, Aschner JL, Aschner M. Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes Molecular Brain Research. 137: 11-22. PMID 15950756 DOI: 10.1016/J.Molbrainres.2005.02.006  0.354
2005 Fitsanakis VA, Piccola G, Aschner JL, Aschner M. Manganese transport by rat brain endothelial (RBE4) cell-based transwell model in the presence of astrocyte conditioned media. Journal of Neuroscience Research. 81: 235-43. PMID 15948148 DOI: 10.1002/Jnr.20560  0.338
2005 Erikson KM, Dorman DC, Lash LH, Aschner M. Persistent alterations in biomarkers of oxidative stress resulting from combined in utero and neonatal manganese inhalation. Biological Trace Element Research. 104: 151-63. PMID 15894815 DOI: 10.1385/Bter:104:2:151  0.336
2005 Fitsanakis VA, Aschner M. The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity. Toxicology and Applied Pharmacology. 204: 343-54. PMID 15845423 DOI: 10.1016/J.Taap.2004.11.013  0.31
2005 Aschner M, Erikson KM, Dorman DC. Manganese dosimetry: species differences and implications for neurotoxicity. Critical Reviews in Toxicology. 35: 1-32. PMID 15742901 DOI: 10.1080/10408440590905920  0.4
2005 Wu Q, Sidoryk M, Mutkus L, Zielińska M, Albrecht J, Aschner M. Acrylamide stimulates glutamine uptake in Fischer 344 rat astrocytes by a mechanism involving upregulation of the amino acid transport system N. Annals of the New York Academy of Sciences. 1053: 435-443. DOI: 10.1196/Annals.1344.038  0.329
2004 Aschner M, Syversen T. Neurotoxicology: Principles and considerations of in vitro assessment Atla Alternatives to Laboratory Animals. 32: 323-327. PMID 15651915 DOI: 10.1177/026119290403200402  0.321
2004 Erikson KM, Dobson AW, Dorman DC, Aschner M. Manganese exposure and induced oxidative stress in the rat brain. The Science of the Total Environment. 334: 409-16. PMID 15504526 DOI: 10.1016/J.Scitotenv.2004.04.044  0.35
2004 Shanker G, Aschner JL, Syversen T, Aschner M. Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury Molecular Brain Research. 128: 48-57. PMID 15337317 DOI: 10.1016/J.Molbrainres.2004.05.022  0.341
2004 Erikson KM, Dorman DC, Lash LH, Dobson AW, Aschner M. Airborne manganese exposure differentially affects end points of oxidative stress in an age- and sex-dependent manner. Biological Trace Element Research. 100: 49-62. PMID 15258319 DOI: 10.1385/Bter:100:1:049  0.318
2004 Stredrick DL, Stokes AH, Worst TJ, Freeman WM, Johnson EA, Lash LH, Aschner M, Vrana KE. Manganese-induced cytotoxicity in dopamine-producing cells. Neurotoxicology. 25: 543-53. PMID 15183009 DOI: 10.1016/J.Neuro.2003.08.006  0.373
2004 Shanker G, Hampson RE, Aschner M. Methylmercury stimulates arachidonic acid release and cytosolic phospholipase A2 expression in primary neuronal cultures. Neurotoxicology. 25: 399-406. PMID 15019302 DOI: 10.1016/J.Neuro.2003.08.008  0.301
2004 Costa LG, Aschner M, Vitalone A, Syversen T, Soldin OP. Developmental neuropathology of environmental agents. Annual Review of Pharmacology and Toxicology. 44: 87-110. PMID 14744240 DOI: 10.1146/Annurev.Pharmtox.44.101802.121424  0.301
2003 Shanker G, Syversen T, Aschner M. Astrocyte-Mediated Methylmercury Neurotoxicity Biological Trace Element Research. 95: 1-10. PMID 14555794 DOI: 10.1385/Bter:95:1:1  0.364
2003 Zheng W, Aschner M, Ghersi-Egea JF. Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicology and Applied Pharmacology. 192: 1-11. PMID 14554098 DOI: 10.1016/S0041-008X(03)00251-5  0.319
2003 Yang J, Aschner M. Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitro model for studies on chlorpyrifos transport Neurotoxicology. 24: 741-745. PMID 12900088 DOI: 10.1016/S0161-813X(03)00025-1  0.323
2003 Aschner M, Cao CC, Wu Q, Friedman MA. The acute effects of acrylamide on astrocyte functions. Annals of the New York Academy of Sciences. 993: 296-304; discussion . PMID 12853321 DOI: 10.1111/J.1749-6632.2003.Tb07537.X  0.341
2003 Dobson AW, Weber S, Dorman DC, Lash LK, Erikson KM, Aschner M. Oxidative stress is induced in the rat brain following repeated inhalation exposure to manganese sulfate. Biological Trace Element Research. 93: 113-26. PMID 12835496 DOI: 10.1385/Bter:93:1-3:113  0.372
2003 Erikson KM, Aschner M. Manganese neurotoxicity and glutamate-GABA interaction. Neurochemistry International. 43: 475-80. PMID 12742094 DOI: 10.1016/S0197-0186(03)00037-8  0.352
2003 Qu H, Syversen T, Aschner M, Sonnewald U. Effect of methylmercury on glutamate metabolism in cerebellar astrocytes in culture. Neurochemistry International. 43: 411-416. PMID 12742086 DOI: 10.1016/S0197-0186(03)00029-9  0.313
2003 Shanker G, Aschner M. Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants Molecular Brain Research. 110: 85-91. PMID 12573536 DOI: 10.1016/S0169-328X(02)00642-3  0.341
2002 Allen JW, Shanker G, Tan KH, Aschner M. The consequences of methylmercury exposure on interactive functions between astrocytes and neurons. Neurotoxicology. 23: 755-759. PMID 12520765 DOI: 10.1016/S0161-813X(01)00076-6  0.375
2002 Allen JW, Mutkus LA, Aschner M. Chronic ethanol produces increased taurine transport and efflux in cultured astrocytes. Neurotoxicology. 23: 693-700. PMID 12520759 DOI: 10.1016/S0161-813X(02)00027-X  0.312
2002 Erikson K, Aschner M. Manganese causes differential regulation of glutamate transporter (GLAST) taurine transporter and metallothionein in cultured rat astrocytes. Neurotoxicology. 23: 595-602. PMID 12428731 DOI: 10.1016/S0161-813X(02)00012-8  0.383
2002 Erikson KM, Suber RL, Aschner M. Glutamate/aspartate transporter (GLAST), taurine transporter and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate or manganese sulfate. Neurotoxicology. 23: 281-8. PMID 12387356 DOI: 10.1016/S0161-813X(02)00041-4  0.406
2002 Weber S, Dorman DC, Lash LH, Erikson K, Vrana KE, Aschner M. Effects of manganese (Mn) on the developing rat brain: oxidative-stress related endpoints. Neurotoxicology. 23: 169-75. PMID 12224758 DOI: 10.1016/S0161-813X(02)00014-1  0.385
2002 Aschner M, Shanker G, Erikson K, Yang J, Mutkus LA. The uptake of manganese in brain endothelial cultures. Neurotoxicology. 23: 165-8. PMID 12224757 DOI: 10.1016/S0161-813X(02)00056-6  0.327
2002 Worley CG, Bombick D, Allen JW, Suber RL, Aschner M. Effects of manganese on oxidative stress in CATH.a cells. Neurotoxicology. 23: 159-164. PMID 12224756 DOI: 10.1016/S0161-813X(02)00028-1  0.337
2002 Aschner M, Walker SJ. The neuropathogenesis of mercury toxicity Molecular Psychiatry. 7. PMID 12142946 DOI: 10.1038/Sj.Mp.4001176  0.302
2002 Erikson KM, Shihabi ZK, Aschner JL, Aschner M. Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations. Biological Trace Element Research. 87: 143-56. PMID 12117224 DOI: 10.1385/Bter:87:1-3:143  0.327
2002 Sonnewald U, Qu H, Aschner M. Pharmacology and toxicology of astrocyte-neuron glutamate transport and cycling Journal of Pharmacology and Experimental Therapeutics. 301: 1-6. PMID 11907150 DOI: 10.1124/Jpet.301.1.1  0.316
2002 Aschner M. Neurotoxic mechanisms of fish-borne methylmercury Environmental Toxicology and Pharmacology. 12: 101-104. DOI: 10.1016/S1382-6689(02)00028-5  0.32
2001 Aschner M, Seegal RF. Selected presentations and general discussion: Session IX summary and research needs Neurotoxicology. 22: 849-852. PMID 11829420 DOI: 10.1016/S0161-813X(01)00090-0  0.393
2001 Aschner M, Mutkus L, Allen JW. Aspartate and glutamate transport in acutely and chronically ethanol exposed neonatal rat primary astrocyte cultures Neurotoxicology. 22: 601-605. PMID 11770881 DOI: 10.1016/S0161-813X(01)00039-0  0.325
2001 Shanker G, Aschner M. Identification and characterization of uptake systems for cystine and cysteine in cultured astrocytes and neurons: Evidence for methylmercury-targeted disruption of astrocyte transport Journal of Neuroscience Research. 66: 998-1002. PMID 11746429 DOI: 10.1002/Jnr.10066  0.349
2001 Yang J, Mutkus LA, Sumner D, Stevens JT, Eldridge JC, Strandhoy JW, Aschner M. Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-conditioned medium. Molecular Brain Research. 97: 43-50. PMID 11744161 DOI: 10.1016/S0169-328X(01)00296-0  0.305
2001 Shanker G, Allen JW, Mutkus LA, Aschner M. Methylmercury inhibits cysteine uptake in cultured primary astrocytes, but not in neurons. Brain Research. 914: 159-165. PMID 11578608 DOI: 10.1016/S0006-8993(01)02791-3  0.344
2001 Hidalgo J, Aschner M, Zatta P, Vašák M. Roles of the metallothionein family of proteins in the central nervous system Brain Research Bulletin. 55: 133-145. PMID 11470309 DOI: 10.1016/S0361-9230(01)00452-X  0.311
2001 Shanker G, Allen JW, Mutkus LA, Aschner M. The uptake of cysteine in cultured primary astrocytes and neurons Brain Research. 902: 156-163. PMID 11384608 DOI: 10.1016/S0006-8993(01)02342-3  0.312
2001 Allen JW, Mutkus LA, Aschner M. Methylmercury-mediated inhibition of 3H-d-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase Brain Research. 902: 92-100. PMID 11376598 DOI: 10.1016/S0006-8993(01)02375-7  0.34
2001 Aschner M, Allen JW, Mutkus LA, Cao CC. Ethanol-induced swelling in neonatal rat primary astrocyte cultures. Brain Research. 900: 219-226. PMID 11334801 DOI: 10.1016/S0006-8993(01)02314-9  0.332
2001 Allen JW, Shanker G, Aschner M. Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons Brain Research. 894: 131-140. PMID 11245823 DOI: 10.1016/S0006-8993(01)01988-6  0.335
2001 Allen JW, Mutkus LA, Aschner M. Mercuric chloride, but not methylmercury, inhibits glutamine synthetase activity in primary cultures of cortical astrocytes Brain Research. 891: 148-157. PMID 11164818 DOI: 10.1016/S0006-8993(00)03185-1  0.386
2000 Aschner M. Manganese: Brain transport and emerging research needs Environmental Health Perspectives. 108: 429-432. PMID 10852840 DOI: 10.1289/Ehp.00108S3429  0.374
2000 Aschner M, Yao CP, Allen JW, Tan KH. Methylmercury alters glutamate transport in astrocytes Neurochemistry International. 37: 199-206. PMID 10812205 DOI: 10.1016/S0197-0186(00)00023-1  0.353
2000 Stokes AH, Lewis DY, Lash LH, Jerome WG, Grant KW, Aschner M, Vrana KE. Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis. Brain Research. 858: 1-8. PMID 10700589 DOI: 10.1016/S0006-8993(99)02329-X  0.328
2000 Yao CP, Allen JW, Mutkus LA, Xu SB, Tan KH, Aschner M. Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity Brain Research. 855: 32-38. PMID 10650127 DOI: 10.1016/S0006-8993(99)02211-8  0.303
1999 Yao CP, Allen JW, Aschner M. Metallothioneins attenuate methylmercury-induced neurotoxicity in cultured astrocytes and astrocytoma cells. Annals of the New York Academy of Sciences. 890: 223-226. PMID 10668428 DOI: 10.1111/J.1749-6632.1999.Tb07997.X  0.321
1999 Zheng W, Zhao Q, Slavkovich V, Aschner M, Graziano JH. Alteration of iron homeostasis following chronic exposure to manganese in rats. Brain Research. 833: 125-32. PMID 10375687 DOI: 10.1016/S0006-8993(99)01558-9  0.318
1999 Aschner M, Allen JW, Kimelberg HK, LoPachin RM, Streit WJ. Glial cells in neurotoxicity development. Annual Review of Pharmacology and Toxicology. 39: 151-73. PMID 10331080 DOI: 10.1146/Annurev.Pharmtox.39.1.151  0.31
1999 Yao CP, Allen JW, Conklin DR, Aschner M. Transfection and overexpression of metallothionein-I in neonatal rat primary astrocyte cultures and in astrocytoma cells increases their resistance to methylmercury-induced cytotoxicity Brain Research. 818: 414-420. PMID 10082827 DOI: 10.1016/S0006-8993(98)01229-3  0.316
1998 Aschner M, Conklin DR, Yao CP, Allen JW, Tan KH. Induction of astrocyte metallothioneins (MTs) by zinc confers resistance against the acute cytotoxic effects of methylmercury on cell swelling, Na+ uptake, and K+ release Brain Research. 813: 254-261. PMID 9838151 DOI: 10.1016/S0006-8993(98)00947-0  0.36
1998 Aschner M, Vitarella D, Allen JW, Conklin DR, Cowan KS. Methylmercury-induced inhibition of regulatory volume decrease in astrocytes: Characterization of osmoregulator efflux and its reversal by amiloride Brain Research. 811: 133-142. PMID 9804925 DOI: 10.1016/S0006-8993(98)00629-5  0.329
1998 Hutson SM, Berkich D, Drown P, Xu B, Aschner M, LaNoue KF. Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism Journal of Neurochemistry. 71: 863-874. PMID 9681479 DOI: 10.1046/J.1471-4159.1998.71020863.X  0.324
1998 Aschner M, Vitarella D, Allen JW, Conklin DR, Cowan KS. Methylmercury-induced astrocytic swelling is associated with activation of the Na+/H+ antiporter, and is fully reversed by amiloride Brain Research. 799: 207-214. PMID 9675283 DOI: 10.1016/S0006-8993(98)00399-0  0.323
1997 Aschner M, Lorscheider FL, Cowan KS, Conklin DR, Vimy MJ, Lash LH. Metallothionein induction in fetal rat brain and neonatal primary astrocyte cultures by in utero exposure to elemental mercury vapor (Hg0). Brain Research. 778: 222-32. PMID 9462895 DOI: 10.1016/S0006-8993(97)01095-0  0.36
1997 Aschner M, Conklin DR, Aschner JL. Induction of metallothionein-I (MT-I) mRNA in primary astrocyte cultures is mediated by hypotonicity and not ethanol (EtOH) per se Brain Research. 770: 289-293. PMID 9372231 DOI: 10.1016/S0006-8993(97)00772-5  0.3
1997 Aschner M. Astrocyte metallothioneins (MTs) and their neuroprotective role Annals of the New York Academy of Sciences. 825: 334-347. PMID 9369999 DOI: 10.1111/J.1749-6632.1997.Tb48445.X  0.356
1997 Aschner M, Cherian MG, Klaassen CD, Palmiter RD, Erickson JC, Bush AI. Metallothioneins in brain--the role in physiology and pathology. Toxicology and Applied Pharmacology. 142: 229-42. PMID 9070344 DOI: 10.1006/Taap.1996.8054  0.342
1996 Vitarella D, Conklin DR, Kimelberg HK, Aschner M. Metallothionein induction protects swollen rat primary astrocyte cultures from methylmercury-induced inhibition of regulatory volume decrease Brain Research. 738: 213-221. PMID 8955515 DOI: 10.1016/S0006-8993(96)00778-0  0.375
1996 Vitarella D, Kimelberg HK, Aschner M. Inhibition of regulatory volume decrease in swollen rat primary astrocyte cultures by methylmercury is due to increased amiloride-sensitive Na+ uptake Brain Research. 732: 169-178. PMID 8891281 DOI: 10.1016/0006-8993(96)00518-5  0.309
1996 Cowan K, Conklin D, Aschner M. Metallothionein induction by bismuth in neonatal rat primary astrocyte cultures Brain Research. 732: 106-112. PMID 8891274 DOI: 10.1016/0006-8993(96)00503-3  0.301
1996 Aschner M. The functional significance of brain metallothioneins Faseb Journal. 10: 1129-1136. PMID 8751715 DOI: 10.1096/Fasebj.10.10.8751715  0.344
1995 Rising L, Vitarella D, Kimelberg HK, Aschner M. Cadmium chloride (CdCl2)-induced metallothionein (MT) expression in neonatal rat primary astrocyte cultures Brain Research. 678: 91-98. PMID 7620903 DOI: 10.1016/0006-8993(95)00170-U  0.325
1995 Rising L, Vitarella D, Kimelberg HK, Aschner M. Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity Journal of Neurochemistry. 65: 1562-1568. PMID 7561850 DOI: 10.1046/J.1471-4159.1995.65041562.X  0.325
1994 Aschner M, Gannon M. Manganese (Mn) transport across the rat blood-brain barrier: Saturable and transferrin-dependent transport mechanisms Brain Research Bulletin. 33: 345-349. PMID 8293318 DOI: 10.1016/0361-9230(94)90204-6  0.325
1994 Aschner M, Mullaney KJ, Wagoner D, Lash LH, Kimelberg HK. Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures. Brain Research. 664: 133-40. PMID 7895022 DOI: 10.1016/0006-8993(94)91963-1  0.306
1994 Dave V, Mullaney KJ, Goderie S, Kimelberg HK, Aschner M. Astrocytes as mediators of methylmercury neurotoxicity: Effects on D-aspartate and serotonin uptake Developmental Neuroscience. 16: 222-231. PMID 7705225 DOI: 10.1159/000112110  0.304
1993 Dave V, Vitarella D, Aschner JL, Fletcher P, Kimelberg HK, Aschner M. Lead increases inositol 1,4,5-triphosphate levels but does not interfere with calcium transients in primary rat astrocytes Brain Research. 618: 9-18. PMID 8402182 DOI: 10.1016/0006-8993(93)90422-J  0.31
1993 Albrecht J, Talbot M, Kimelberg HK, Aschner M. The role of sulfhydryl groups and calcium in the mercuric chloride-induced inhibition of glutamate uptake in rat primary astrocyte cultures Brain Research. 607: 249-254. PMID 8097664 DOI: 10.1016/0006-8993(93)91513-R  0.32
1993 Aschner M, Du YL, Gannon M, Kimelberg HK. Methylmercury-induced alterations in excitatory amino acid transport in rat primary astrocyte cultures Brain Research. 602: 181-186. PMID 8095428 DOI: 10.1016/0006-8993(93)90680-L  0.33
1992 Aschner M, Gannon M, Kimelberg HK. Manganese uptake and efflux in cultured rat astrocytes Journal of Neurochemistry. 58: 730-735. PMID 1729413 DOI: 10.1111/J.1471-4159.1992.Tb09778.X  0.327
1992 Aschner M, Aschner JL. Cellular and molecular effects of trimethyltin and triethyltin: Relevance to organotin neurotoxicity Neuroscience and Biobehavioral Reviews. 16: 427-435. PMID 1480339 DOI: 10.1016/S0149-7634(05)80184-8  0.351
1992 Aschner M, Gannon M, Kimelberg HK. Interactions of trimethyl tin (TMT) with rat primary astrocyte cultures: altered uptake and efflux of rubidium, l-glutamate and D-aspartate Brain Research. 582: 181-185. PMID 1356582 DOI: 10.1016/0006-8993(92)90131-R  0.321
1991 Aschner M, Aschner JL. Manganese neurotoxicity: Cellular effects and blood-brain barrier transport Neuroscience and Biobehavioral Reviews. 15: 333-340. PMID 1956602 DOI: 10.1016/S0149-7634(05)80026-0  0.373
1991 Aschner M, Eberle NB, Kimelberg HK. Interactions of methylmercury with rat primary astrocyte cultures: methylmercury efflux Brain Research. 554: 10-14. PMID 1933294 DOI: 10.1016/0006-8993(91)90165-R  0.329
1991 Aschner M, Chen R, K. Kimelberg H. Effects of mercury and lead on rubidium uptake and efflux in cultured rat astrocytes Brain Research Bulletin. 26: 639-642. PMID 1868363 DOI: 10.1016/0361-9230(91)90108-V  0.336
1990 Aschner M, Aschner JL. Manganese transport across the blood-brain barrier: Relationship to iron homeostasis Brain Research Bulletin. 24: 857-860. PMID 2372703 DOI: 10.1016/0361-9230(90)90152-P  0.319
1990 Aschner M, Eberle NB, Miller K, Kimelberg HK. Interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling Brain Research. 530: 245-250. PMID 2265356 DOI: 10.1016/0006-8993(90)91290-W  0.349
1990 Aschner M, Eberle NB, Goderie S, Kimelberg HK. Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system Brain Research. 521: 221-228. PMID 2207661 DOI: 10.1016/0006-8993(90)91546-S  0.33
1990 Aschner M, Aschner JL. Mercury neurotoxicity: Mechanisms of blood-brain barrier transport Neuroscience and Biobehavioral Reviews. 14: 169-176. PMID 2190116 DOI: 10.1016/S0149-7634(05)80217-9  0.338
1989 Aschner M. Brain, Kidney and Liver 203Hg‐Methyl Mercury Uptake in the Rat: Relationship to the Neutral Amino Acid Carrier Pharmacology &Amp; Toxicology. 65: 17-20. PMID 2780503 DOI: 10.1111/J.1600-0773.1989.Tb01119.X  0.314
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