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Ernst W. Spannhake - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biostatistics Biology, Epidemiology, Environmental Health
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Zhao Y, Zhao J, Mialki RK, Wei J, Spannhake EW, Salgia R, Natarajan V. Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L56-63. PMID 23624790 DOI: 10.1152/Ajplung.00417.2012  0.314
2012 Zhao J, Chen Q, Li H, Myerburg M, Spannhake EW, Natarajan V, Zhao Y. Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells Cellular Signalling. 24: 77-85. PMID 21871564 DOI: 10.1016/J.Cellsig.2011.08.004  0.395
2011 Gao M, Singh A, Macri K, Reynolds C, Singhal V, Biswal S, Spannhake EW. Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Respiratory Research. 12: 92. PMID 21752292 DOI: 10.1186/1465-9921-12-92  0.31
2009 He D, Su Y, Usatyuk PV, Spannhake EW, Kogut P, Solway J, Natarajan V, Zhao Y. Lysophosphatidic Acid Enhances Pulmonary Epithelial Barrier Integrity and Protects Endotoxin-induced Epithelial Barrier Disruption and Lung Injury Journal of Biological Chemistry. 284: 24123-24132. PMID 19586906 DOI: 10.1074/Jbc.M109.007393  0.376
2009 Zhao Y, Usatyuk PV, Gorshkova IA, He D, Wang T, Moreno-Vinasco L, Geyh AS, Breysse PN, Samet JM, Spannhake EW, Garcia JG, Natarajan V. Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 40: 19-30. PMID 18617679 DOI: 10.1165/Rcmb.2008-0105Oc  0.347
2008 Ramanathan M, Lee WK, Spannhake EW, Lane AP. Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells. American Journal of Rhinology. 22: 115-21. PMID 18416964 DOI: 10.2500/Ajr.2008.22.3136  0.308
2008 He D, Natarajan V, Stern R, Gorshkova IA, Solway J, Spannhake EW, Zhao Y. Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPbeta in human bronchial epithelial cells. The Biochemical Journal. 412: 153-62. PMID 18294142 DOI: 10.1042/Bj20071649  0.33
2007 Lee WK, Ramanathan M, Spannhake EW, Lane AP. The cigarette smoke component acrolein inhibits expression of the innate immune components IL-8 and human beta-defensin 2 by sinonasal epithelial cells. American Journal of Rhinology. 21: 658-63. PMID 18201443 DOI: 10.2500/Ajr.2007.21.3094  0.32
2007 Ramanathan M, Lee WK, Dubin MG, Lin S, Spannhake EW, Lane AP. Sinonasal epithelial cell expression of toll-like receptor 9 is decreased in chronic rhinosinusitis with polyps. American Journal of Rhinology. 21: 110-6. PMID 17283572 DOI: 10.2500/Ajr.2007.21.2997  0.323
2007 Zhao Y, He D, Stern R, Kalari S, Spannhake EW, Natarajan V. 71 Lysophosphatidic Acid Induces Cyclooxygenase 2 Expression And Prostaglandin E2 Production In Human Primary Bronchial Epithelial Cells. Journal of Investigative Medicine. 55. DOI: 10.1136/Jim-55-02-71  0.334
2006 Boodoo S, Spannhake EW, Powell JD, Horton MR. Differential regulation of hyaluronan-induced IL-8 and IP-10 in airway epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L479-86. PMID 16581825 DOI: 10.1152/Ajplung.00518.2005  0.368
2006 Saatian B, Zhao Y, He D, Georas SN, Watkins T, Spannhake EW, Natarajan V. Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells Biochemical Journal. 393: 657-668. PMID 16197369 DOI: 10.1042/Bj20050791  0.318
2005 Traore K, Trush MA, George M, Spannhake EW, Anderson W, Asseffa A. Signal transduction of phorbol 12-myristate 13-acetate (PMA)-induced growth inhibition of human monocytic leukemia THP-1 cells is reactive oxygen dependent. Leukemia Research. 29: 863-79. PMID 15978937 DOI: 10.1016/J.Leukres.2004.12.011  0.335
2001 Frank R, Liu MC, Spannhake EW, Mlynarek S, Macri K, Weinmann GG. Repetitive ozone exposure of young adults: Evidence of persistent small airway dysfunction American Journal of Respiratory and Critical Care Medicine. 164: 1253-1260. PMID 11673219 DOI: 10.1164/Ajrccm.164.7.2010043  0.319
1996 Yu XY, Undem BJ, Spannhake EW. Protective effect of substance P on permeability of airway epithelial cells in culture American Journal of Physiology - Lung Cellular and Molecular Physiology. 271. PMID 8997258 DOI: 10.1152/Ajplung.1996.271.6.L889  0.319
1996 Spannhake EW. Down-regulation of canine airway mast cell function following exposure to ozone in vivo. Experimental Lung Research. 22: 163-178. PMID 8706634 DOI: 10.3109/01902149609050845  0.411
1995 Takahashi N, Yu XY, Schofield BH, Kleeberger SR, Scott AL, Hasegawa S, Spannhake EW. Expression of ICAM-1 in airway epithelium after acute ozone exposure in the mouse Journal of Applied Physiology. 79: 1753-1761. PMID 8594038 DOI: 10.1152/Jappl.1995.79.5.1753  0.368
1994 Gabrielson EW, Yu XY, Spannhake EW. Comparison of the toxic effects of hydrogen peroxide and ozone on cultured human bronchial epithelial cells Environmental Health Perspectives. 102: 972-974. PMID 9738213 DOI: 10.1289/Ehp.94102972  0.317
1994 Yu XY, Schofield BH, Croxton T, Takahashi N, Gabrielson EW, Spannhake EW. Physiologic modulation of bronchial epithelial cell barrier function by polycationic exposure American Journal of Respiratory Cell and Molecular Biology. 11: 188-198. PMID 8049079 DOI: 10.1165/Ajrcmb.11.2.8049079  0.365
1994 Takahashi N, Liu MC, Proud D, Yu XY, Hasegawa S, Spannhake EW. Soluble intracellular adhesion molecule 1 in bronchoalveolar lavage fluid of allergic subjects following segmental antigen challenge American Journal of Respiratory and Critical Care Medicine. 150: 704-709. PMID 7916246 DOI: 10.1164/Ajrccm.150.3.7916246  0.305
1994 Yu XY, Takahashi N, Croxton TL, Spannhake EW. Modulation of bronchial epithelial cell barrier function by in vitro ozone exposure Environmental Health Perspectives. 102: 1068-1072. PMID 7713019 DOI: 10.1289/Ehp.941021068  0.38
1992 Ninomiya H, Hasegawa S, Yu XY, Spannhake EW. Endothelin-1 induces stimulation of prostaglandin synthesis in cells obtained from canine airways by bronchoalveolar lavage Prostaglandins. 43: 401-411. PMID 1584994 DOI: 10.1016/0090-6980(92)90124-C  0.355
1992 Yu XY, Hubbard W, Spannhake EW. Inhibition of canine tracheal smooth muscle by mediators from cultured bronchial epithelial cells American Journal of Physiology - Lung Cellular and Molecular Physiology. 262. PMID 1539679 DOI: 10.1152/Ajplung.1992.262.2.L229  0.322
1991 Canning BJ, Hmieleski RR, Spannhake EW, Jakab GJ. Ozone reduces murine alveolar and peritoneal macrophage phagocytosis: The role of prostanoids American Journal of Physiology - Lung Cellular and Molecular Physiology. 261. PMID 1928362 DOI: 10.1152/Ajplung.1991.261.4.L277  0.342
1991 Rikimaru T, Nakamura M, Yano T, Beck G, Habicht GS, Rennie LL, Widra M, Hirshman CA, Boulay MG, Spannhake EW. Mediators, initiating the inflammatory response, released in organ culture by full-thickness human skin explants exposed to the irritant, sulfur mustard. The Journal of Investigative Dermatology. 96: 888-97. PMID 1710639 DOI: 10.1111/1523-1747.Ep12475292  0.318
1990 Turner CR, Spannhake EW. Acute topical steroid administration blocks mast cell increase and the late asthmatic response of the canine peripheral airways. The American Review of Respiratory Disease. 141: 421-427. PMID 2301857 DOI: 10.1164/Ajrccm/141.2.421  0.334
1990 Yoss EB, Spannhake EW, Flynn JT, Fish JE, Peters SP. Arachidonic acid metabolism in normal human alveolar macrophages: stimulus specificity for mediator release and phospholipid metabolism, and pharmacologic modulation in vitro and in vivo American Journal of Respiratory Cell and Molecular Biology. 2: 69-80. PMID 2155013 DOI: 10.1165/Ajrcmb/2.1.69  0.301
1989 Turner CR, Kleeberger SR, Spannhake EW. Preexposure to ozone blocks the antigen-induced late asthmatic response of the canine peripheral airways Journal of Toxicology and Environmental Health. 28: 363-371. PMID 2585540 DOI: 10.1080/15287398909531355  0.391
1989 Kleeberger SR, Kolbe J, Turner C, Spannhake EW. Exposure to 1 ppm ozone attenuates the immediate antigenic response of canine peripheral airways Journal of Toxicology and Environmental Health. 28: 349-362. PMID 2585539 DOI: 10.1080/15287398909531354  0.346
1988 Turner CR, Kolbe J, Spannhake EW. Rapid increase in mast cell numbers in canine central and peripheral airways Journal of Applied Physiology. 65: 445-451. PMID 3403488 DOI: 10.1152/Jappl.1988.65.1.445  0.387
1988 Beckett WS, Black C, Turner C, Spannhake EW, Menkes HA. In vivo exposure to ozone causes increased in vitro responses of small airways. The American Review of Respiratory Disease. 137: 1236-1238. PMID 3195820 DOI: 10.1164/Ajrccm/137.5.1236  0.366
1988 Farrukh IS, Michael JR, Peters SP, Sciuto AM, Adkinson NF, Freeland HS, Paky A, Spannhake EW, Summer WR, Gurtner GH. The role of cyclooxygenase and lipoxygenase mediators in oxidant-induced lung injury. The American Review of Respiratory Disease. 137: 1343-9. PMID 3144200 DOI: 10.1164/Ajrccm/137.6.1343  0.325
1987 Kleeberger SR, Kolbe J, Adkinson NF, Peters SP, Spannhake EW. Thromboxane contributes to the immediate antigenic response of canine peripheral airways Journal of Applied Physiology. 62: 1589-1595. PMID 3597229 DOI: 10.1152/Jappl.1987.62.4.1589  0.38
1987 Kolbe J, Kleeberger SR, Menkes HA, Spannhake EW. Hypocapnia-induced constriction of the canine peripheral airways exhibits tachyphylaxis Journal of Applied Physiology. 63: 497-504. PMID 3115940 DOI: 10.1152/Jappl.1987.63.2.497  0.382
1986 Farrukh IS, Sciuto AM, Spannhake EW, Gurtner GH, Michael JR. Leukotriene D4 increases pulmonary vascular permeability and pressure by different mechanisms in the rabbit. The American Review of Respiratory Disease. 134: 229-32. PMID 3740648 DOI: 10.1164/Arrd.1986.134.2.229  0.315
1986 Kelly L, Kolbe J, Mitzner W, Spannhake EW, Bromberger-Barnea B, Menkes H. Bronchial blood flow affects recovery from constriction in dog lung periphery Journal of Applied Physiology. 60: 1954-1959. PMID 3722062 DOI: 10.1152/Jappl.1986.60.6.1954  0.341
1986 Kelly LJ, Mitzner W, Spannhake EW, Bromberger-Barnea B, Menkes HA. Pulmonary blood flow affects recovery from constriction in dog lung periphery. Journal of Applied Physiology (Bethesda, Md. : 1985). 60: 1554-60. PMID 3519568 DOI: 10.1152/Jappl.1986.60.5.1554  0.328
1986 Kleeberger SR, Kolbe J, Adkinson NF, Peters SP, Spannhake EW. Central role of cyclooxygenase in the response of canine peripheral airways to antigen Journal of Applied Physiology. 61: 1309-1315. PMID 2430928 DOI: 10.1152/Jappl.1986.61.4.1309  0.388
1985 Spannhake EW, Adams TL, Kleeberger SR. Influence of chronic antigen exposure on the metabolism of PGH2 by microsomal preparations of airway and parenchymal tissues in the sheep Prostaglandins. 30: 1041-1055. PMID 3911292 DOI: 10.1016/0090-6980(85)90175-3  0.382
1985 Wagner EM, Kleeberger SR, Spannhake EW, Adams GK. Increased in vitro airway responsiveness in sheep following repeated exposure to antigen in vivo. Journal of Applied Physiology (Bethesda, Md. : 1985). 59: 1874-8. PMID 3908441 DOI: 10.1152/Jappl.1985.59.6.1874  0.37
1985 Kleeberger SR, Wagner EM, Adams GK, Dannenberg AM, Spannhake EW. Effect of repeated antigen exposure on antigen-and mediator-induced bronchospasm in sheep. Journal of Applied Physiology (Bethesda, Md. : 1985). 59: 1866-73. PMID 3865925 DOI: 10.1152/Jappl.1985.59.6.1866  0.314
1985 Weinmann GG, Spannhake EW, Bromberger-Barnea B, Menkes HA. Tonic β-sympathetic activity in the lung periphery in anesthetized dogs Journal of Applied Physiology. 59: 979-984. PMID 2997106 DOI: 10.1152/Jappl.1985.59.3.979  0.336
1983 Spannhake EW, Colombo JL, Craigo PA, McNamara DB, Hyman AL, Kadowitz PJ. Evidence for modification of pulmonary cyclooxygenase activity by endotoxin in the dog Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 54: 191-198. PMID 6402470 DOI: 10.1152/Jappl.1983.54.1.191  0.376
1981 Hyman AL, Higashida RT, Spannhake EW, Kadowitz PJ. Pulmonary vasoconstrictor responses to graded decreases in precapillary blood P(O2) in intact-chest cat Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 51: 1009-1016. PMID 7298414 DOI: 10.1152/Jappl.1981.51.4.1009  0.309
1980 Spannhake EW, Levin JL, Mellion BT, Gruetter CA, Hyman AL, Kadowitz PJ. Reversal of 5HT-induced bronchoconstriction by PGI 2: Distribution of central and peripheral actions Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 49: 521-527. PMID 7009520 DOI: 10.1152/Jappl.1980.49.3.521  0.348
1978 Spannhake EW, Lemen RJ, Wegmann MJ, Hyman AL, Kadowitz PJ. Effects of arachidonic acid and prostaglandins on lung function in the intact dog. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 44: 397-405. PMID 632180 DOI: 10.1152/Jappl.1978.44.3.397  0.381
1978 Hyman AL, Spannhake EW, Chapnick BM, McNamara DB, Mathe AA, Kadowitz PJ. Effect of dihomo-gamma-linolenic acid on the canine pulmonary vascular bed The American Journal of Physiology. 234. PMID 623313 DOI: 10.1152/Ajpheart.1978.234.2.H133  0.373
1978 Kadowitz PJ, Chapnick BM, Feigen LP, Hyman AL, Nelson PK, Spannhake EW. Pulmonary and systemic vasodilator effect of the newly discovered prostaglandin PGI 2 Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 45: 408-413. PMID 359514 DOI: 10.1152/Jappl.1978.45.3.408  0.306
1977 Kadowitz PJ, Gruetter CA, McNamara DB, Gorman RR, Spannhake EW, Hyman AL. Comparative effects of endoperoxide PGH2 and an analog on the pulmonary vascular bed. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 42: 953-8. PMID 881396 DOI: 10.1152/Jappl.1977.42.6.953  0.36
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