Robert L. Hamlin - Publications

Affiliations: 
Veterinary Biosciences Ohio State University, Columbus, Columbus, OH 
Area:
Molecular Biology, Cell Biology, Medical Biophysics
Website:
https://vet.osu.edu/assets/pdf/depts/biosciences/biosNewsletter/biosNewsletter_200506.pdf

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Abbott-Johnson K, Pierce KV, Roof S, Del Rio CL, Hamlin R. Acute Effects of Pimobendan on Cardiac Function in Dogs With Tachycardia Induced Dilated Cardiomyopathy: A Randomized, Placebo-Controlled, Crossover Study. Frontiers in Veterinary Science. 8: 646437. PMID 34277749 DOI: 10.3389/fvets.2021.646437  0.322
2020 Muir WW, Hamlin RL. Myocardial Contractility: Historical and Contemporary Considerations. Frontiers in Physiology. 11: 222. PMID 32296340 DOI: 10.3389/Fphys.2020.00222  0.362
2020 Hamlin RL, Keene BW. Species Differences in Cardiovascular Physiology that Affect Pharmacology and Toxicology Current Opinion in Toxicology. 106-113. DOI: 10.1016/J.Cotox.2020.07.004  0.314
2019 Brockway B, Liddie S, Moddrelle D, Morton X, Delahanty T, Hamlin R. Discrimination of the effects of three cardiac ion channel blockers using ECG biomarkers and arrhythmia incidence in St. Kitts green monkeys (Chlorocebus Sabaeus). Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31963047 DOI: 10.1016/J.Vascn.2019.05.050  0.31
2019 Geist B, LaRose A, Ueyama Y, Youngblood BL, Palmieri M, Del Rio C, Hamlin R. Serial coronary microembolization induced ischemic cardiomyopathy: Model refinement in the closed-chest Beagle dog. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31963041 DOI: 10.1016/J.Vascn.2019.05.054  0.305
2019 Ueyama Y, Del Rio C, Palmieri M, Geist B, Hamlin R. Evaluation of left ventricular function with continuous echocardiography concomitant with left ventricular pressure measurement in isoflurane anesthetized rats for safety pharmacology study. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31963030 DOI: 10.1016/J.Vascn.2019.05.065  0.386
2019 Geist B, Youngblood BL, Ueyama Y, LaRose A, Hamlin R, Evanchik MJ, Del Rio C. Telemetered left-ventricular pressure in Yucatan mini-pigs: Chronic evaluation in a novel genetic model of non-obstructed hypertrophic cardiomyopathy. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962959 DOI: 10.1016/J.Vascn.2019.05.142  0.355
2018 Brockway R, Brockway M, Brockway B, Hamlin R. Comparison of one- and three-lead ECG to measure cardiac intervals and differentiate drug-induced multi-channel block. Journal of Pharmacological and Toxicological Methods. 93: 80-89. PMID 29704608 DOI: 10.1016/J.Vascn.2018.04.004  0.322
2018 Youngblood B, Ferris E, Geist B, Ueyama Y, Muir WW, Rio Cd, Hamlin RL. Effects of sympathetic tone in the QT interval and heart rate variability indices of beagle dogs Journal of Pharmacological and Toxicological Methods. 93: 172. DOI: 10.1016/J.Vascn.2018.01.556  0.382
2018 Ueyama Y, del Rio C, Geist B, Palmieri M, Roof S, Youngblood B, Hamlin RL. Evaluation of chronic angiotensin-converting-enzyme inhibition in rats with transverse aortic constriction induced cardiac hypertrophy Journal of Pharmacological and Toxicological Methods. 93: 129-130. DOI: 10.1016/J.Vascn.2018.01.435  0.306
2018 Geist B, Rio Cd, Ueyama Y, Roof S, Derakhchan K, Muir W, Hamlin RL. Systemic and left-ventricular hemodynamics in neonatal rats: Response to sodium nitroprusside and phenylephrine Journal of Pharmacological and Toxicological Methods. 93: 125. DOI: 10.1016/J.Vascn.2018.01.421  0.322
2017 Roof SR, Ueyama Y, Mazhari R, Hamlin RL, Hartman JC, Ziolo MT, Reardon JE, Del Rio CL. CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction-A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat. Frontiers in Physiology. 8: 894. PMID 29209225 DOI: 10.3389/Fphys.2017.00894  0.411
2017 Limprasutr V, Pirintr P, Kijtawornrat A, Hamlin RL. An increasing electromechanical window is a predictive marker of ventricular fibrillation in anesthetized rabbit with ischemic heart. Experimental Animals. PMID 29162767 DOI: 10.1538/Expanim.17-0100  0.335
2017 Limprasutr V, Saengklub N, Meedech P, Kijtawornrat A, Hamlin RL. Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes. The Journal of Toxicological Sciences. 42: 579-587. PMID 28904293 DOI: 10.2131/Jts.42.579  0.346
2017 Cunha DNQ, Del Rio CL, Youngblood BL, Ferris EL, Geist GE, Ueyama Y, Franz LC, Mathur S, Hamlin RL. Efficacy of a mephentermine-based product as a vasopressor and a cardiac performance enhancer when given intramuscularly to cattle. Journal of Veterinary Pharmacology and Therapeutics. PMID 28804906 DOI: 10.1111/Jvp.12444  0.378
2017 Saengklub N, Limprasutr V, Sawangkoon S, Hamlin RL, Kijtawornrat A. Dronedarone attenuates the duration of atrial fibrillation in a dog model of sustained atrial fibrillation. Experimental Animals. PMID 28381818 DOI: 10.1538/Expanim.17-0002  0.752
2017 Limprasutr V, Brown T, Hamlin RL, Kijtawornrat A. Evaluation of Index of Cardio-electrophysiological Balance (iCEB) and Short-term Variability of QT Intervals (STV) to Predict the Risk of Ventricular Fibrillation in Anesthetized Rabbit Model of Ischemia/Reperfusion Journal of Pharmacological and Toxicological Methods. 88: 228. DOI: 10.1016/J.Vascn.2017.09.197  0.33
2017 Hamlin R. Potential Value of Excluding Uncontrollable Changes in Cerebral Cortical Activity (CCA) on Identifying Effects of Test Articles on Cardiovascular (CV) Function in Dogs: Heart Rate (HR) As an Example Journal of Pharmacological and Toxicological Methods. 88: 227-228. DOI: 10.1016/J.Vascn.2017.09.195  0.348
2017 Ferris E, Bennett S, del Rio C, Geist G, Youngblood B, Hamlin R, McConnell P. Effects of Preload on Left Ventricular Pressure-Derived Indices of Contractility and Oxygen Consumption: Relationships with Direct Invasive Measurements in Anesthetized Sheep Journal of Pharmacological and Toxicological Methods. 88: 227. DOI: 10.1016/J.Vascn.2017.09.193  0.343
2017 Geist GE, Render K, del Rio C, Ferris E, Youngblood B, Hamlin R. Chronic Enalapril and Carvedilol Therapy in Beagle Dogs with Induced Chronic Ischemic Left-Ventricular Dysfunction: Effects on Angiotensin Responsiveness Journal of Pharmacological and Toxicological Methods. 88: 222-223. DOI: 10.1016/J.Vascn.2017.09.179  0.345
2017 del Rio C, Fernandes S, Youngblood B, Geist E, Ferris E, Ueyama Y, Evanchik M, Hamlin R. Assessing Myocardial Contractility In Vivo When Cycling Velocity is Unchanged - Flying Under the dP/dt Radar: Evidence From Conscious Telemetered Beagle Dogs Journal of Pharmacological and Toxicological Methods. 88: 211. DOI: 10.1016/J.Vascn.2017.09.142  0.326
2016 Saengklub N, Youngblood B, Del Rio C, Sawangkoon S, Hamlin RL, Kijtawornrat A. Short-term effects of oral dronedarone administration on cardiac function, blood pressure and electrocardiogram in conscious telemetry dogs. The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science. PMID 26922916 DOI: 10.1292/Jvms.15-0481  0.774
2016 Saengklub N, Limprasutr V, Sawangkoon S, Buranakarl C, Hamlin RL, Kijtawornrat A. Acute effects of intravenous dronedarone on electrocardiograms, hemodynamics and cardiac functions in anesthetized dogs. The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science. 78: 177-86. PMID 26346474 DOI: 10.1292/Jvms.15-0413  0.785
2016 Youngblood B, del Rio C, Render K, Geist B, Ueyama Y, Wallery J, Hamlin R. Characterization of canine models of heart failure with reduced and preserved ejection fraction Journal of Pharmacological and Toxicological Methods. 81: 375. DOI: 10.1016/J.Vascn.2016.02.131  0.367
2016 Saengklub N, Limprasutr V, Rio Cd, Hamlin RL, Kijtawornrat A. Dronedarone prevents atrial fibrillation in dog model of sustained atrial fibrillation Journal of Pharmacological and Toxicological Methods. 81: 373-374. DOI: 10.1016/J.Vascn.2016.02.127  0.33
2016 Geist GE, del Rio C, Youngblood B, Render K, Ueyama Y, Hamlin R. A model of acute congestion with progressive induction of pulmonary edema in sheep with chronic ischemic left-ventricular dysfunction: Preliminary results Journal of Pharmacological and Toxicological Methods. 81: 372. DOI: 10.1016/J.Vascn.2016.02.122  0.343
2016 Hamlin R. Why may the ECG vary so much when a “Modified Lead II” is taken by telemetry? Journal of Pharmacological and Toxicological Methods. 81: 368. DOI: 10.1016/J.Vascn.2016.02.109  0.305
2015 Roof SR, Boslett J, Russell D, Del Rio C, Alecusan J, Zweier JL, Ziolo MT, Hamlin R, Mohler PJ, Curran J. Insulin-like growth factor 1 prevents diastolic and systolic dysfunction associated with cardiomyopathy and preserves adrenergic sensitivity. Acta Physiologica (Oxford, England). PMID 26399932 DOI: 10.1111/Apha.12607  0.328
2015 Meedech P, Saengklub N, Limprasutr V, Kalandakanond-Thongsong S, Kijtawornrat A, Hamlin RL. Transmural dispersion of repolarization and cardiac remodeling in ventricles of rabbit with right ventricular hypertrophy. Journal of Pharmacological and Toxicological Methods. 71: 129-36. PMID 25305588 DOI: 10.1016/J.Vascn.2014.09.012  0.397
2015 Youngblood B, del Rio C, Sutayatram S, Hamlin R, Muir B. Effects of fentanyl analgesia on electromechanical indices in conscious beagle dogs Journal of Pharmacological and Toxicological Methods. 75: 188. DOI: 10.1016/J.Vascn.2015.08.102  0.312
2015 Roof S, del Rio C, Hamlin R, Ziolo M. Diastolic dysfunction induced by either chronic isoproterenol or renal wrapping: Evidence of altered left ventricular filling pressures, compliance and Ca2+ handling Journal of Pharmacological and Toxicological Methods. 75: 187. DOI: 10.1016/J.Vascn.2015.08.098  0.328
2015 Limprasutr V, Saengklub N, Kijtawornrat A, Sawangkoon S, Hamlin RL. Effects of blood pressure on electro-mechanical window in anesthetized rabbits Journal of Pharmacological and Toxicological Methods. 75: 185-186. DOI: 10.1016/J.Vascn.2015.08.094  0.723
2015 del Rio C, Youngblood B, Ueyama Y, George R, Hamlin R. Lengthening of the electro-mechanical window (EMw) in dogs with pacing-induced left-ventricular dysfunction: Correlation with indices of diastolic function Journal of Pharmacological and Toxicological Methods. 75: 184. DOI: 10.1016/J.Vascn.2015.08.090  0.393
2014 Muir WW, Ueyama Y, Pedraza-Toscano A, Vargas-Pinto P, Delrio CL, George RS, Youngblood BL, Hamlin RL. Arterial blood pressure as a predictor of the response to fluid administration in euvolemic nonhypotensive or hypotensive isoflurane-anesthetized dogs. Journal of the American Veterinary Medical Association. 245: 1021-7. PMID 25313813 DOI: 10.2460/Javma.245.9.1021  0.732
2014 da Cunha DN, Pereira VG, Favarato LS, Okano BS, Daibert AP, Monteiro BS, Araujo MR, Carvalho PH, Hamlin RL, Del Carlo RJ. Acute and chronic observations of complete atrioventricular block in rats. Laboratory Animals. 48: 237-249. PMID 24759570 DOI: 10.1177/0023677214530905  0.331
2014 Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA. Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. Journal of Cardiovascular Pharmacology and Therapeutics. 19: 121-32. PMID 24288396 DOI: 10.1177/1074248413508003  0.329
2014 Bonilla IM, Vargas-Pinto P, Nishijima Y, Pedraza-Toscano A, Ho HT, Long VP, Belevych AE, Glynn P, Houmsse M, Rhodes T, Weiss R, Hund TJ, Hamlin RL, Györke S, Carnes CA. Ibandronate and ventricular arrhythmia risk. Journal of Cardiovascular Electrophysiology. 25: 299-306. PMID 24256556 DOI: 10.1016/J.Hrthm.2012.09.100  0.722
2014 Kijtawornrat A, Ueyama Y, del Rio C, Sawangkoon S, Buranakarl C, Chaiyabutr N, Hamlin RL. Test of the usefulness of a paradigm to identify potential cardiovascular liabilities of four test articles with varying pharmacological properties in anesthetized guinea pigs. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 458-68. PMID 24189130 DOI: 10.1093/Toxsci/Kft244  0.761
2014 Ben-Amotz R, Bonagura J, Velayutham M, Hamlin R, Burns P, Adin C. Intraperitoneal bilirubin administration decreases infarct area in a rat coronary ischemia/reperfusion model Frontiers in Physiology. 5. DOI: 10.3389/Fphys.2014.00053  0.345
2014 Ueyama Y, Geroge RS, Rio CLd, Hamlin RL. Effect of changes in heart rate on load-independent contractility: Chronotropic-inotropism in anesthetized guinea pigs Journal of Pharmacological and Toxicological Methods. 70: 346. DOI: 10.1016/J.Vascn.2014.03.126  0.347
2014 Meedech P, Limprasutr V, Saengklub N, Kalandakanond-Thongsong S, Kijtawornrat A, Hamlin R. Prolongation of QT interval related to hERG mRNA expression in rabbits with right ventricular hypertrophy Journal of Pharmacological and Toxicological Methods. 70: 343. DOI: 10.1016/J.Vascn.2014.03.118  0.303
2014 Kijtawornrat A, Ueyama Y, del Rio C, Sawangkoon S, Buranakarl C, Chaiyabutr N, Hamlin RL. Relationship between dP/dtmax, QA interval, contractility index, and preload recruitable stroke work in anesthetized guinea pigs Journal of Pharmacological and Toxicological Methods. 70: 342. DOI: 10.1016/J.Vascn.2014.03.115  0.708
2014 Youngblood B, Kloepfer P, Ueyama Y, George R, Sutayatram S, Hardy R, Gallacher M, Ottinger S, Hamlin R, del Rio C. A preload and lusitropy corrected dP/dtmax-derived index of contractility: Evaluation in telemetered beagle dogs treated with amrinone Journal of Pharmacological and Toxicological Methods. 70: 340-341. DOI: 10.1016/J.Vascn.2014.03.109  0.303
2014 Rio Cd, Youngblood B, Kloepfer P, Ueyama Y, George R, Wallery J, Reardon J, Hamlin R. Differential effects of a novel ino-dilator in conscious dogs with normal or dilated-cardiomyopathic ventricles: A look through left-ventricular pressure-volume analyses Journal of Pharmacological and Toxicological Methods. 70: 324. DOI: 10.1016/J.Vascn.2014.03.054  0.397
2014 del Rio CL, Youngblood BL, George RS, Ueyama Y, Lynne GM, Arnold S, Hamlin RL. Vasomera™, a Novel VPAC2-Selective Vasoactive Intestinal Peptide Agonist, Improves Ventriculo-Arterial Coupling and Decreases Myocardial Demand in Sheep with Induced Ischemic Heart Failure Journal of Cardiac Failure. 20: S96. DOI: 10.1016/J.Cardfail.2014.06.269  0.338
2014 del Rio CL, George RS, Youngblood BL, Ueyama Y, Hartman C, Hamlin RL, Reardon J. Acute Oral Efficacy of a Slow-Release Nitroxyl (HNO) Donor in Conscious Dogs with Induced Dilated-Cardiomyopathy: A Look through Left-Ventricular Pressure-Volume Analyses Journal of Cardiac Failure. 20: S95. DOI: 10.1016/J.Cardfail.2014.06.268  0.377
2013 Glukhov AV, Hage LT, Hansen BJ, Pedraza-Toscano A, Vargas-Pinto P, Hamlin RL, Weiss R, Carnes CA, Billman GE, Fedorov VV. Sinoatrial node reentry in a canine chronic left ventricular infarct model: role of intranodal fibrosis and heterogeneity of refractoriness. Circulation. Arrhythmia and Electrophysiology. 6: 984-94. PMID 23960214 DOI: 10.1161/Circep.113.000404  0.754
2013 Rio CLd, George R, Kloepfer P, Ueyama Y, Youngblood B, Georgopoulos L, Arnold S, Hamlin RL. Vasomera™, A Novel Vpac2-Selective Vasoactive Intestinal Peptide Agonist, Enhances Contractility And Decreases Myocardial Demand In Dogs With Both Normal Hearts And With Pacing-Induced Dilated Cardiomyopathy Journal of the American College of Cardiology. 61. DOI: 10.1016/S0735-1097(13)60645-2  0.336
2013 Pedraza-Toscano A, Vargas-Pinto P, Kijtawornrat A, Hamlin R. Electrocardiographic effects of escalating doses of cilobradine, cisapride and dofetilide in anesthetized cats: A new model for torsadogenecity Journal of Pharmacological and Toxicological Methods. 68: e40. DOI: 10.1016/J.Vascn.2013.01.147  0.716
2013 Vargas-Pinto P, Pedraza-Toscano A, Hamlin R, Carnes C. What do biphasic P waves in the surface electrocardiogram mean? Journal of Pharmacological and Toxicological Methods. 68: e40. DOI: 10.1016/J.Vascn.2013.01.146  0.692
2013 Kijtawornrat A, Sawangkoon S, Komolvanich S, Buranakarl C, Hamlin R. The utility of the isolated weanling pig hearts as a model for drug safety evaluation Journal of Pharmacological and Toxicological Methods. 68: e30. DOI: 10.1016/J.Vascn.2013.01.111  0.745
2013 del Rio C, Youngblood B, Kloepfer P, Ueyama Y, Pedraza-Toscano A, Vargas-Pinto P, Schmidt J, Wallery J, Ishizaka T, Hamlin R. Load-dependence of the QA-interval: Responses to sodium nitroprusside in awake dogs instrumented for left-ventricular pressure-volume analyses Journal of Pharmacological and Toxicological Methods. 68: e15. DOI: 10.1016/J.Vascn.2013.01.061  0.749
2013 del Rio C, Ueyama Y, Kloepfer P, Youngblood B, Pedraza-Toscano A, Vargas-Pinto P, Muir W, Hamlin R. Beat-to-beat cardiac-output assessment in a canine model of controlled hemorrhagic shock: Impedance cardiography versus conductance-based left-ventricular volumes Journal of Pharmacological and Toxicological Methods. 68: e14-e15. DOI: 10.1016/J.Vascn.2013.01.060  0.762
2013 Kijtawornrat A, Ueyama Y, del Rio C, Sawangkoon S, Buranakarl C, Chaiyabutr N, Hamlin RL. Use of an anesthetized guinea pig to identify proarrhythmic, inotropic, and lusitropic liabilities of test articles in safety pharmacology study Journal of Pharmacological and Toxicological Methods. 68: e3. DOI: 10.1016/J.Vascn.2013.01.020  0.711
2013 Ishizaka T, Ueyama Y, Pedraza-Toscano A, Kloepfer P, del Rio C, Hamlin R. Bimodel inotropic response of dl-sotalol: Cardiovascular evaluation via pressure–volume analysis in isoflurane-anesthetized beagle dogs Journal of Pharmacological and Toxicological Methods. 68: e2. DOI: 10.1016/J.Vascn.2013.01.017  0.728
2012 Kijtawornrat A, Sawangkoon S, Hamlin RL. Assessment of QT-prolonging drugs in the isolated normal and failing rabbit hearts. The Journal of Toxicological Sciences. 37: 455-62. PMID 22687985 DOI: 10.2131/Jts.37.455  0.781
2012 Schwarzwald CC, Kedo M, Birkmann K, Hamlin RL. Relationship of heart rate and electrocardiographic time intervals to body mass in horses and ponies. Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology. 14: 343-50. PMID 22560718 DOI: 10.1016/J.Jvc.2012.03.001  0.328
2012 Hamlin RL, del Rio C. dP/dt(max)--a measure of 'baroinometry'. Journal of Pharmacological and Toxicological Methods. 66: 63-5. PMID 22326878 DOI: 10.1016/J.Vascn.2012.01.001  0.332
2012 del Rio CL, Pedraza-Toscano A, Vargas-Pinto P, Ueyama Y, Wallery J, Williams V, Thibaud D, Hamlin RL. A model of heart failure via mitral regurgitation and tachypacing: Decreased exercise capacity and functional/neuro‐humoral remodeling Journal of Pharmacological and Toxicological Methods. 66: 196. DOI: 10.1016/J.Vascn.2012.08.132  0.747
2012 Hawk MA, Vinci TM, Hamlin RL, Roche BM, Coffee MS, Gonzalez E. A proof of concept study for evaluating antihypertensive compounds in awake, chronically-instrumented, pharmacologically hypertensive monkeys Journal of Pharmacological and Toxicological Methods. 66: 193. DOI: 10.1016/J.Vascn.2012.08.124  0.61
2012 Pedraza-Toscano AM, Vargas-Pinto P, del Rio C, Hamlin RL. Night/day differences in common electrocardiographic indices of arrhythmic liability in telemetered dogs Journal of Pharmacological and Toxicological Methods. 66: 189-190. DOI: 10.1016/J.Vascn.2012.08.110  0.714
2012 Kijtawornrat A, Sawangkoon S, Del Rio C, Hamlin RL. Comparison of cardiac electrophysiological and mechanical effects of torsadogens in the isolated normal and failing rabbit hearts Journal of Pharmacological and Toxicological Methods. 66: 183. DOI: 10.1016/J.Vascn.2012.08.085  0.773
2012 del Rio CL, McConnell PI, Nitzan Y, Vargas-Pinto P, Pedraza-Toscano A, Brown T, Ueyama Y, Abraham WT, Verheye S, Hamlin RL. Pressure-dependent left-ventricular unloading in a chronic model of ischemic heart failure: Evaluation of a novel intra-atrial shunt Journal of Pharmacological and Toxicological Methods. 66: 176-177. DOI: 10.1016/J.Vascn.2012.08.062  0.775
2012 Hamlin RL, Brockway M, Brockway B, Olson J, Martin R, Risdal J. Validation of a novel system for preclinical assessment of ventricular arrhythmias Journal of Pharmacological and Toxicological Methods. 66: 173. DOI: 10.1016/J.Vascn.2012.08.049  0.347
2012 Saengklub N, Limprasutr V, Meedech P, Kijtawornrat A, del Rio C, Hamlin RL. Use of QA interval to assess cardiac contractility in anesthetized rat Journal of Pharmacological and Toxicological Methods. 66: 161. DOI: 10.1016/J.Vascn.2012.08.008  0.33
2012 Vargas-Pinto PA, Pedraza-Toscano AM, Hamlin RL, Del Rio C. Potential for increased pulmonary vascular pressure due to verapamil Journal of Pharmacological and Toxicological Methods. 66: 161. DOI: 10.1016/J.Vascn.2012.08.007  0.713
2011 Rottenberg EM, Heard J, Hamlin R, Sun BC, Awad H. Abdominal only CPR during cardiac arrest for a patient with an LVAD during resternotomy: A case report Journal of Cardiothoracic Surgery. 6. PMID 21762506 DOI: 10.1186/1749-8090-6-91  0.318
2011 Shiry LJ, Hamlin RL. Measuring high pressure baroreceptor sensitivity in the rat. Journal of Pharmacological and Toxicological Methods. 64: 97-101. PMID 21338701 DOI: 10.1016/J.Vascn.2011.02.001  0.343
2011 Belevych AE, Terentyev D, Terentyeva R, Nishijima Y, Sridhar A, Hamlin RL, Carnes CA, Györke S. The relationship between arrhythmogenesis and impaired contractility in heart failure: role of altered ryanodine receptor function. Cardiovascular Research. 90: 493-502. PMID 21273243 DOI: 10.1093/Cvr/Cvr025  0.369
2011 Hamlin RL, Altschuld RA. Extrapolation from mouse to man. Circulation. Cardiovascular Imaging. 4: 2-4. PMID 21245362 DOI: 10.1161/Circimaging.110.961979  0.354
2011 Vargas-Pinto PA, Pedraza-Toscano AM, del Rio C, Hamlin RL. Time course of hypoxic-induced changes in pulmonary arterial pressures in anesthetized dogs exposed to FiO2s of 12% and 10%: A model of vascular pulmonary hypertension Journal of Pharmacological and Toxicological Methods. 64: e54. DOI: 10.1016/j.vascn.2011.03.186  0.704
2011 Roche BM, Hamlin R, Monroe P, Hassler C, Moutvic R, Reynolds J. The drug development decision: Does the current preclinical testing paradigm provide the best safety? Journal of Pharmacological and Toxicological Methods. 64: e33-e34. DOI: 10.1016/J.Vascn.2011.03.119  0.595
2011 McConnell PI, del Rio CL, Nitzan Y, Ueyama Y, Vargas P, Pedraza A, Jacoby M, Hamlin RL, Keren G, Abraham WT, Verheye S. Pilot Evaluation of a Novel Intra-Atrial Valved-Shunt (V-Wave Device) for Pressure-Dependent Cardiac Unloading in a Chronic Model of Ischemic Heart Failure Journal of Cardiac Failure. 17: S40. DOI: 10.1016/J.Cardfail.2011.06.134  0.402
2011 Kijtawornrat A, Sawangkoon S, Simonetti OP, Hamlin RL. Body surface potentials generated by the heart of normal guinea pigs Thai Journal of Veterinary Medicine. 41: 463-469.  0.723
2010 Hamlin RL. QRS in pigs versus in dogs. Journal of Pharmacological and Toxicological Methods. 62: 4-5. PMID 20800783 DOI: 10.1016/J.Vascn.2010.04.009  0.333
2010 Kijtawornrat A, Ziolo MT, Nishijima Y, Roche BM, Hamlin RL. Effects of sarcolemmal Ca(2+) entry, ryanodine function, and kinase inhibitors on a rabbit model of heart failure. International Heart Journal. 51: 285-90. PMID 20716847 DOI: 10.1536/Ihj.51.285  0.647
2010 Gandolf AR, Fahlman A, Arnemo JM, Dooley JL, Hamlin R. Baseline normal values and phylogenetic class of the electrocardiogram of anesthetized free-ranging brown bears (Ursus arctos) Journal of Wildlife Diseases. 46: 724-730. PMID 20688678 DOI: 10.7589/0090-3558-46.3.724  0.324
2010 Lamb AP, Meurs KM, Hamlin RL. Correlation of heart rate to body weight in apparently normal dogs. Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology. 12: 107-10. PMID 20634163 DOI: 10.1016/J.Jvc.2010.04.001  0.334
2010 Panyasing Y, Kijtawornrat A, Del Rio C, Carnes C, Hamlin RL. Uni- or bi-ventricular hypertrophy and susceptibility to drug-induced torsades de pointes. Journal of Pharmacological and Toxicological Methods. 62: 148-56. PMID 20435152 DOI: 10.1016/J.Vascn.2010.04.007  0.374
2010 Kijtawornrat A, Panyasing Y, Del Rio C, Hamlin RL. Assessment of ECG interval and restitution parameters in the canine model of short QT syndrome. Journal of Pharmacological and Toxicological Methods. 61: 231-7. PMID 20156577 DOI: 10.1016/J.Vascn.2010.02.001  0.361
2010 del Rio CL, Kijtawornrat A, Hamlin R, Billman G. Beat-to-beat changes in QT/RR relationships induced by ischemia on dogs prone to sudden death are modeled by QT-shortening, not lengthening Journal of Pharmacological and Toxicological Methods. 62: e45-e46. DOI: 10.1016/J.Vascn.2010.11.154  0.314
2010 Kijtawornrat A, Panyasing Y, del Rio C, Schmidt JJ, Snedden L, Hamlin RL. Magnesium prevents drug-induced torsades de pointes in the rabbit model of ventricular hypertrophy: Arrhythmia repeatability and instability Journal of Pharmacological and Toxicological Methods. 62: e40. DOI: 10.1016/J.Vascn.2010.11.136  0.352
2010 del Rio CL, Kijtawornrat A, Snedden L, Ueyama Y, Panyasing Y, Probst D, Smith J, Hamlin R, Muir W. Assessing mechanical liability in vivo in the era of vasoactive drugs: The usefulness of left ventricular pressure volume relationships Journal of Pharmacological and Toxicological Methods. 62: e27. DOI: 10.1016/J.Vascn.2010.11.093  0.358
2010 Panyasing Y, Kijtawornrat AU, Del Rio C, Schmidt JJ, Snedden L, Brown T, Hamlin RL. Significant of Uni-or Bi-ventricular hypertrophy in development of torsades de pointes Journal of Pharmacological and Toxicological Methods. 62: e3. DOI: 10.1016/J.Vascn.2010.11.011  0.357
2010 Rio Cd, Kijtawornrat A, Panyasing Y, Hamlin R, Reardon J, Mazhari R. Intravenous Infusion of the Novel HNO Donor, CXL-1020, Improves Cardiac Mechano-Energetics: Comparison With Sodium Nitroprusside Journal of Cardiac Failure. 16. DOI: 10.1016/J.Cardfail.2010.06.250  0.353
2009 Varian KD, Kijtawornrat A, Gupta SC, Torres CA, Monasky MM, Hiranandani N, Delfin DA, Rafael-Fortney JA, Periasamy M, Hamlin RL, Janssen PM. Impairment of diastolic function by lack of frequency-dependent myofilament desensitization rabbit right ventricular hypertrophy. Circulation. Heart Failure. 2: 472-81. PMID 19808378 DOI: 10.1161/Circheartfailure.109.853200  0.398
2009 Atkins C, Bonagura J, Ettinger S, Fox P, Gordon S, Haggstrom J, Hamlin R, Keene B, Luis-Fuentes V, Stepien R. Guidelines for the diagnosis and treatment of canine chronic valvular heart disease. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 23: 1142-50. PMID 19780929 DOI: 10.1111/J.1939-1676.2009.0392.X  0.312
2009 Sridhar A, Nishijima Y, Terentyev D, Khan M, Terentyeva R, Hamlin RL, Nakayama T, Gyorke S, Cardounel AJ, Carnes CA. Chronic heart failure and the substrate for atrial fibrillation. Cardiovascular Research. 84: 227-36. PMID 19567484 DOI: 10.1093/Cvr/Cvp216  0.38
2009 Khan M, Meduru S, Mohan IK, Kuppusamy ML, Wisel S, Kulkarni A, Rivera BK, Hamlin RL, Kuppusamy P. Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart. Journal of Molecular and Cellular Cardiology. 47: 275-87. PMID 19376124 DOI: 10.1016/J.Yjmcc.2009.04.005  0.335
2009 Khan M, Mohan IK, Kutala VK, Kotha SR, Parinandi NL, Hamlin RL, Kuppusamy P. Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation. Antioxidants & Redox Signaling. 11: 725-38. PMID 18855521 DOI: 10.1089/Ars.2008.2155  0.321
2009 Khan M, Kuppusamy P, Hamlin RL. Non-invasive monitoring of in situ pO2 during engraftment of stem cells in the infarct heart Journal of Pharmacological and Toxicological Methods. 60: 255. DOI: 10.1016/J.Vascn.2009.04.184  0.302
2009 del Rio C, Kijtawornrat A, Panyasing Y, Snedden L, Probst D, Schmidt J, Hamlin R. Non-invasive continuous cardiac output assessment via impedance cardiography in a canine model of controlled hemorrhagic shock Journal of Pharmacological and Toxicological Methods. 60: 253. DOI: 10.1016/J.Vascn.2009.04.176  0.319
2009 del Rio C, Snedden L, Ueyama Y, Panyasing Y, Zwijnenberg R, Kijtawornrat A, Hamlin R, Muir W. Concentration-dependent changes in ECG-derived indices of repolarization triggered by Isoflurane: A study in telemetered beagle dogs Journal of Pharmacological and Toxicological Methods. 60: 248-249. DOI: 10.1016/J.Vascn.2009.04.160  0.311
2009 Panyasing Y, Kijtawornrat A, del Rio C, Snedden L, Mongkolmaneepol T, Schmidt J, Hamlin R. Analysis of dynamic restitution of ECG parameters in the rabbit langendorff heart exposed to drugs that lengthen or abbreviate QT Journal of Pharmacological and Toxicological Methods. 60: 242. DOI: 10.1016/J.Vascn.2009.04.136  0.344
2009 Pedraza-Toscano A, Vargas-Pinto PA, Hamlin RL. Advances in recording and interpreting of the mouse ECG and differences among strains Journal of Pharmacological and Toxicological Methods. 60: 239-240. DOI: 10.1016/J.Vascn.2009.04.127  0.695
2008 Kijtawornrat A, Roche BM, Hamlin RL. A canine model of sustained atrial fibrillation induced by rapid atrial pacing and phenylephrine. Comparative Medicine. 58: 490-3. PMID 19004376  0.644
2008 Hamlin RL, Kijtawornrat A. Use of the rabbit with a failing heart to test for torsadogenicity. Pharmacology & Therapeutics. 119: 179-85. PMID 18691764 DOI: 10.1016/J.Pharmthera.2008.03.011  0.428
2008 Schober KE, Stern JA, DaCunha DN, Pedraza-Toscano AM, Shemanski D, Hamlin RL. Estimation of left ventricular filling pressure by Doppler echocardiography in dogs with pacing-induced heart failure. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 22: 578-85. PMID 18466238 DOI: 10.1111/J.1939-1676.2008.0099.X  0.766
2008 Hamlin RL. How many ECG leads are required for in vivo studies in safety pharmacology? Journal of Pharmacological and Toxicological Methods. 57: 161-8. PMID 18417371 DOI: 10.1016/J.Vascn.2008.03.004  0.322
2008 Zhao L, Roche BM, Wessale JL, Kijtawornrat A, Lolly JL, Shemanski D, Hamlin RL. Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment. Life Sciences. 82: 495-502. PMID 18215719 DOI: 10.1016/J.Lfs.2007.12.010  0.687
2008 Roche BM, Kijtawornrat A, Lolly J, Schmidt J, Hamlin R. His bundle electrogram: A safety assessment of conductivity in anesthetized dogs Journal of Pharmacological and Toxicological Methods. 58: 172. DOI: 10.1016/J.Vascn.2008.05.106  0.626
2008 Hassler CR, Coffee M, Hawk M, Stonerook M, Ellinger M, Vinci T, Wood B, Lordo R, Hamlin R. Cardiovascular safety evaluations assessment in exercise stress and heart failure models Journal of Pharmacological and Toxicological Methods. 58: 160. DOI: 10.1016/J.Vascn.2008.05.062  0.334
2008 Hamlin RL, Kijtawornrat A, Roche B, Lolly J. A comprehensive assessment of drug effects on cardiovascular function in anesthetized beagle dog Journal of Pharmacological and Toxicological Methods. 58: 159. DOI: 10.1016/J.Vascn.2008.05.056  0.639
2008 Kijtawornrat A, Roche BM, Lolly JL, Hamlin RL. A canine model of relatively sustained atrial fibrillation induced by rapid atrial pacing and phenylephrine Journal of Pharmacological and Toxicological Methods. 58: 149-150. DOI: 10.1016/J.Vascn.2008.05.019  0.648
2007 Fuller GA, Bicer S, Hamlin RL, Yamaguchi M, Reiser PJ. Increased myosin heavy chain-beta with atrial expression of ventricular light chain-2 in canine cardiomyopathy. Journal of Cardiac Failure. 13: 680-6. PMID 17923362 DOI: 10.1016/J.Cardfail.2007.05.006  0.719
2007 Nishijima Y, Sridhar A, Viatchenko-Karpinski S, Shaw C, Bonagura JD, Abraham WT, Joshi MS, Bauer JA, Hamlin RL, Györke S, Feldman DS, Carnes CA. Chronic cardiac resynchronization therapy and reverse ventricular remodeling in a model of nonischemic cardiomyopathy. Life Sciences. 81: 1152-9. PMID 17884106 DOI: 10.1016/J.Lfs.2007.08.022  0.408
2007 Nakayama T, Nishijima Y, Miyamoto M, Hamlin RL. Effects of 4 classes of cardiovascular drugs on ventricular function in dogs with mitral regurgitation. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 21: 445-50. PMID 17552449 DOI: 10.1111/J.1939-1676.2007.Tb02988.X  0.599
2007 Schwarzwald CC, Hamlin RL, Bonagura JD, Nishijima Y, Meadows C, Carnes CA. Atrial, SA nodal, and AV nodal electrophysiology in standing horses: normal findings and electrophysiologic effects of quinidine and diltiazem. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 21: 166-75. PMID 17338165 DOI: 10.1111/J.1939-1676.2007.Tb02943.X  0.35
2007 da Cunha DN, Hamlin RL, Billman GE, Carnes CA. n-3 (omega-3) polyunsaturated fatty acids prevent acute atrial electrophysiological remodeling. British Journal of Pharmacology. 150: 281-5. PMID 17179952 DOI: 10.1038/Sj.Bjp.0706977  0.31
2007 Hamlin RL. Animal models of ventricular arrhythmias. Pharmacology & Therapeutics. 113: 276-95. PMID 17070922 DOI: 10.1016/J.Pharmthera.2006.08.006  0.38
2007 Hamlin RL. The guinea pig in cardiac safety pharmacology. Journal of Pharmacological and Toxicological Methods. 55: 1-2. PMID 16844389 DOI: 10.1016/J.Vascn.2006.05.003  0.346
2007 Nishijima Y, Pedraza-Toscano A, Kijtawornrat A, Hamlin R. IMPORTANCE OF FREQUENCY CHARACTERISTICS OF ECGS IN MONITORING VARIOUS SPECIES Journal of Pharmacological and Toxicological Methods. 56: e16. DOI: 10.1016/J.Vascn.2007.02.033  0.693
2007 Kijtawornrat A, Roche BM, Lolly JL, Schmidt J, Hamlin RL. PREDICTIVE VALUE OF BEAT-TO-BEAT VARIABILITY IN ISOLATED PERFUSED GUINEA PIG HEART Journal of Pharmacological and Toxicological Methods. 56: e15. DOI: 10.1016/J.Vascn.2007.02.030  0.662
2007 Kijtawornrat A, Viatchenko-Karpinski S, Roche B, Gyorke S, Hamlin R. A POSSIBLE MECHANISM CONTRIBUTING TO DOFETILIDE INDUCED-ARRHYTHMIAS Journal of Pharmacological and Toxicological Methods. 56: e14. DOI: 10.1016/J.Vascn.2007.02.028  0.621
2007 Hamlin RL, Kijtawornrat A, Simonetti O, Roche B, Lolly J, Schmidt J. BODY SURFACE POTENTIALS GENERATED BY HEART FROM NORMAL GUINEA PIG Journal of Pharmacological and Toxicological Methods. 56: e13. DOI: 10.1016/J.Vascn.2007.02.027  0.652
2007 Hamlin RL, Kijtawornrat A, Roche B, Lolly J, Schmidt J. EFFECTS OF ESCALATING CONCENTRATIONS OF SEX HORMONES ON ISOLATED PERFUSED GUINEA PIG HEARTS Journal of Pharmacological and Toxicological Methods. 56: e13. DOI: 10.1016/J.Vascn.2007.02.026  0.662
2007 Roche BM, Kijtawornrat A, Lolly JL, Schmidt JJ, Wood B, Hamlin RL. EFFECTS OF AN IKs AND AN ITO CHANNEL BLOCKER ON CARDIAC PERFORMANCE IN RABBIT AND GUINEA PIG LANGENDORFF PREPARATIONS Journal of Pharmacological and Toxicological Methods. 56. DOI: 10.1016/J.Vascn.2007.02.025  0.323
2007 Roche B, Kijtawornrat A, Lolly J, Nishijima Y, Schmidt J, Hamlin R. THE EFFECTS OF 12-WEEKS OF VENTRICULAR PACING ON CARDIAC PERFORMANCE AND BNP LEVELS IN DOGS Journal of Pharmacological and Toxicological Methods. 56: e12. DOI: 10.1016/J.Vascn.2007.02.024  0.69
2007 Da Cunha DN, Pedraze A, Kuenzler R, Dalal Y, Brockway M, Zhang Y, Hatlestad J, Hamlin R. Trends in Respiration Rate as an Indicator of Worsening Heart Failure Journal of Cardiac Failure. 13: S173. DOI: 10.1016/J.Cardfail.2007.06.657  0.342
2006 Soloviev MV, Hamlin RL, Barrett RM, Chengelis CP, Schaefer GJ. Different species require different correction factors for the QT interval. Cardiovascular Toxicology. 6: 145-57. PMID 17303921 DOI: 10.1385/Ct:6:2:145  0.326
2006 Soloviev MV, Hamlin RL, Shellhammer LJ, Barrett RM, Wally RA, Birchmeier PA, Schaefer GJ. Variations in hemodynamic parameters and ECG in healthy, conscious, freely moving telemetrized beagle dogs. Cardiovascular Toxicology. 6: 51-62. PMID 16845182 DOI: 10.1385/Ct:6:1:51  0.363
2006 Kijtawornrat A, Nishijima Y, Roche BM, Keene BW, Hamlin RL. Use of a failing rabbit heart as a model to predict torsadogenicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 205-12. PMID 16740615 DOI: 10.1093/Toxsci/Kfl025  0.692
2006 Kijtawornrat A, Ozkanlar Y, Keene BW, Roche BM, Hamlin DM, Hamlin RL. Assessment of drug-induced QT interval prolongation in conscious rabbits. Journal of Pharmacological and Toxicological Methods. 53: 168-73. PMID 16290300 DOI: 10.1016/J.Vascn.2005.04.013  0.654
2005 Nishijima Y, Feldman DS, Bonagura JD, Ozkanlar Y, Jenkins PJ, Lacombe VA, Abraham WT, Hamlin RL, Carnes CA. Canine nonischemic left ventricular dysfunction: a model of chronic human cardiomyopathy. Journal of Cardiac Failure. 11: 638-44. PMID 16230269 DOI: 10.1016/J.Cardfail.2005.05.006  0.401
2005 Hamlin RL. Non-drug-related electrocardiographic features in animal models in safety pharmacology. Journal of Pharmacological and Toxicological Methods. 52: 60-76. PMID 15979349 DOI: 10.1016/J.Vascn.2005.04.019  0.386
2005 Ozkanlar Y, Nishijima Y, da Cunha D, Hamlin RL. Acute effects of tacrolimus (FK506) on left ventricular mechanics. Pharmacological Research. 52: 307-12. PMID 15975821 DOI: 10.1016/J.Phrs.2005.05.003  0.387
2005 Ozkanlar Y, Kijtawornrat A, Hamlin RL, Keene BW, Roche BM. Acute cardiovascular effects of tacrolimus in the isolated guinea pig heart. Journal of Veterinary Pharmacology and Therapeutics. 28: 313-6. PMID 15953206 DOI: 10.1111/J.1365-2885.2005.00631.X  0.633
2005 Roche BM, Kijtawornrat A, Hamlin RL, Hamlin DM. Relationship between prolongation of QTc and prolongation of the peak of T (Tp) to the end of T (Te). Journal of Pharmacological and Toxicological Methods. 52: 178-81. PMID 15932797 DOI: 10.1016/J.Vascn.2005.03.004  0.672
2005 Hamlin RL. Geriatric heart diseases in dogs. The Veterinary Clinics of North America. Small Animal Practice. 35: 597-615. PMID 15833561 DOI: 10.1016/J.Cvsm.2005.01.003  0.354
2005 Kijtawornrat A, Hamlin RL, Hamlin DM. Effects of ambasilide in isolated perfused guinea pig heart: use dependence. Cardiovascular Toxicology. 5: 53-62. PMID 15738585 DOI: 10.1385/Ct:5:1:053  0.405
2005 Carnes CA, Nishijima Y, Da Cunha D, Feldman DS, Hamlin RL, Bonagura J. Chronic right ventricular tachypacing results in QRS prolongation and left ventricular dysfunction and dyssynchrony Heart Rhythm. 2: S180. DOI: 10.1016/J.Hrthm.2005.02.562  0.367
2004 Hamlin RL, Kijtawornrat A, Keene BW. How many cardiac cycles must be measured to permit accurate RR, QT, and QTc estimates in conscious dogs? Journal of Pharmacological and Toxicological Methods. 50: 103-8. PMID 15385084 DOI: 10.1016/J.Vascn.2004.03.013  0.354
2004 Hamlin RL, Kijtawornrat A, Keene BW, Nakayama T, Nakayama H, Hamlin DM, Arnold TA. Effects of thalidomide on QTc, inotropy, and lusitropy in the isolated guinea pig heart. Cardiovascular Toxicology. 4: 29-36. PMID 15034203 DOI: 10.1385/Ct:4:1:29  0.405
2004 Boddy KN, Roche BM, Schwartz DS, Nakayama T, Hamlin RL. Evaluation of the six-minute walk test in dogs. American Journal of Veterinary Research. 65: 311-3. PMID 15027678 DOI: 10.2460/Ajvr.2004.65.311  0.75
2004 Hamlin RL, Cruze CA, Mittelstadt SW, Kijtawornrat A, Keene BW, Roche BM, Nakayama T, Nakayama H, Hamlin DM, Arnold T. Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc. Journal of Pharmacological and Toxicological Methods. 49: 15-23. PMID 14670690 DOI: 10.1016/J.Vascn.2003.08.003  0.671
2004 McConnell PI, Cunha Dd, Shipkowitz T, Hee JV, Long PH, Hamlin RL. In vivo safety and accuracy of a clinically applicable telemetered left ventricular pressure module: intermediate-term results Journal of Cardiac Failure. 10: S67. DOI: 10.1016/J.Cardfail.2004.06.179  0.331
2004 Carnes CA, Nishijima Y, Jenkins P, Cunha Dd, Abraham WT, Feldman DS, Hamlin RL. Left ventricular dysfunction and impaired exercise tolerance in a chronic canine model Journal of Cardiac Failure. 10: S37-S38. DOI: 10.1016/J.Cardfail.2004.06.069  0.324
2003 Hamlin RL, Kijtawornrat A, Keene BW, Hamlin DM. QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 437-42. PMID 14600288 DOI: 10.1093/Toxsci/Kfg254  0.331
2003 Chaves AA, Dech SJ, Nakayama T, Hamlin RL, Bauer JA, Carnes CA. Age and anesthetic effects on murine electrocardiography. Life Sciences. 72: 2401-12. PMID 12639705 DOI: 10.1016/S0024-3205(03)00137-1  0.327
2003 Hamlin RL, Nakayama T, Nakayama H, Carnes CA. Effects of changing heart rate on electrophysiological and hemodynamic function in the dog. Life Sciences. 72: 1919-30. PMID 12597991 DOI: 10.1016/S0024-3205(03)00015-8  0.414
2002 Al-Wabel NA, Strauch SM, Keene BW, Nakayama T, Hamlin RL. Electrocardiographic and hemodynamic effects of cisapride alone and combined with erythromycin in anesthetized dogs. Cardiovascular Toxicology. 2: 195-208. PMID 12665665 DOI: 10.1007/S12012-002-0004-5  0.426
2002 Roche BM, Schwartz D, Lehnhard RA, McKeever KH, Nakayama T, Kirby TE, Robitaille PM, Hamlin RL. Changes in concentrations of neuroendocrine hormones and catecholamines in dogs with myocardial failure induced by rapid ventricular pacing. American Journal of Veterinary Research. 63: 1413-7. PMID 12371769 DOI: 10.2460/Ajvr.2002.63.1413  0.762
2002 Meurs KM, Spier AW, Wright NA, Atkins CE, DeFrancesco TC, Gordon SG, Hamlin RL, Keene BW, Miller MW, Moise NS. Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. Journal of the American Veterinary Medical Association. 221: 522-7. PMID 12184702 DOI: 10.2460/Javma.2002.221.522  0.386
2002 Bicer S, Patchell JS, Hamlin DM, Hamlin RL. Acute effects of escalating doses of amiodarone in isolated guinea pig hearts. Journal of Veterinary Pharmacology and Therapeutics. 25: 221-6. PMID 12081617 DOI: 10.1046/J.1365-2885.2002.00408.X  0.713
2002 Bicer S, Nakayama T, Hamlin RL. Effects of chronic oral amiodarone on left ventricular function, ECGs, serum chemistries, and exercise tolerance in healthy dogs. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 16: 247-54. PMID 12041653 DOI: 10.1111/J.1939-1676.2002.Tb02365.X  0.713
2002 Bicer S, Fuller GA, Wilkie DA, Yamaguchi M, Hamlin RL. Amiodarone-induced keratopathy in healthy dogs. Veterinary Ophthalmology. 5: 35-8. PMID 11940246 DOI: 10.1046/J.1463-5224.2002.00208.X  0.685
2001 Bicer S, Nakayama H, Nakayama T, Strauch SM, Hamlin RL. Effects of chronic, oral amiodarone on left ventricular pressure, electrocardiograms, and action potentials from myocardium in vivo and from Purkinje fibers in vitro. Veterinary Therapeutics : Research in Applied Veterinary Medicine. 2: 325-33. PMID 19746655  0.691
2001 Miyamoto M, Nishijima Y, Nakayama T, Hamlin RL. Acute cardiovascular effects of diltiazem in anesthetized dogs with induced atrial fibrillation. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 15: 559-63. PMID 11817061 DOI: 10.1111/J.1939-1676.2001.Tb01591.X  0.63
2001 Muto M, Wakao Y, Morimoto M, Klomkleaw W, Fuller GA, Nakayama T, Oba T, Kasashima Y, Hamlin RL, Yamaguchi M. A semi-immobilization of a partial auricle induces hypertrophy and ultrastructural alteration of cardiomyocytes. International Journal of Cardiology. 81: 189-99. PMID 11744136 DOI: 10.1016/S0167-5273(01)00566-6  0.391
2001 Nakayama H, Nakayama T, Carnes CA, Strauch SM, Hamlin RL. Electrophysiologic and hemodynamic effects of apomorphine in dogs. Toxicology and Applied Pharmacology. 177: 157-61. PMID 11740914 DOI: 10.1006/Taap.2001.9297  0.356
2001 Spier AW, Meurs KM, Muir WW, Lehmkuhl LB, Hamlin RL. Correlation of QT dispersion with indices used to evaluate the severity of familial ventricular arrhythmias in Boxers. American Journal of Veterinary Research. 62: 1481-5. PMID 11560281 DOI: 10.2460/Ajvr.2001.62.1481  0.338
2001 Carnes CA, Chung MK, Nakayama T, Nakayama H, Baliga RS, Piao S, Kanderian A, Pavia S, Hamlin RL, McCarthy PM, Bauer JA, Van Wagoner DR. Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation. Circulation Research. 89: E32-8. PMID 11557745 DOI: 10.1161/Hh1801.097644  0.356
2001 Okamoto Y, Chaves A, Chen J, Kelley R, Jones K, Weed HG, Gardner KL, Gangi L, Yamaguchi M, Klomkleaw W, Nakayama T, Hamlin RL, Carnes C, Altschuld R, Bauer J, et al. Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction. The American Journal of Pathology. 159: 639-50. PMID 11485922 DOI: 10.1016/S0002-9440(10)61735-X  0.331
2001 Nakayama H, Nakayama T, Hamlin RL. Correlation of cardiac enlargement as assessed by vertebral heart size and echocardiographic and electrocardiographic findings in dogs with evolving cardiomegaly due to rapid ventricular pacing. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 15: 217-21. PMID 11380030 DOI: 10.1892/0891-6640(2001)015<0217:Coceaa>2.3.Co;2  0.441
2001 Meurs KM, Spier AW, Wright NA, Hamlin RL. Use of ambulatory electrocardiography for detection of ventricular premature complexes in healthy dogs. Journal of the American Veterinary Medical Association. 218: 1291-2. PMID 11330615 DOI: 10.2460/Javma.2001.218.1291  0.33
2000 Hamlin RL, Nakayama T, Brady JT, Stoll RE. Hemodynamic and electrophysiologic effects of ontazolast in dogs. American Journal of Veterinary Research. 61: 1364-8. PMID 11108180 DOI: 10.2460/Ajvr.2000.61.1364  0.393
2000 Miyamoto M, Nishijima Y, Nakayama T, Hamlin RL. Cardiovascular effects of intravenous diltiazem in dogs with iatrogenic atrial fibrillation. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 14: 445-51. PMID 10935896 DOI: 10.1111/J.1939-1676.2000.Tb02254.X  0.587
2000 Miller TL, Schwartz DS, Nakayama T, Hamlin RL. Effects of acute gastric distention and recovery on tendency for ventricular arrhythmia in dogs. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 14: 436-44. PMID 10935895 DOI: 10.1892/0891-6640(2000)014<0436:Eoagda>2.3.Co;2  0.651
2000 O’Malley P, Smith B, Hamlin R, Nickel J, Nakayama T, MacVicar M, Mann B. A comparison of bolus versus continuous cardiac output in an experimental model of heart failure. Critical Care Medicine. 28: 1985-1990. PMID 10890652 DOI: 10.1097/00003246-200006000-00050  0.366
2000 Bicer S, Schwartz DS, Nakayama T, Hamlin RL. Hemodynamic and electrocardiographic effects of graded doses of amiodarone in healthy dogs anesthetized with morphine/alpha chloralose. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 14: 90-5. PMID 10668823 DOI: 10.1892/0891-6640(2000)014<0090:Haeeog>2.3.Co;2  0.774
2000 Sawangkoon S, Miyamoto M, Nakayama T, Hamlin RL. Acute cardiovascular effects and pharmacokinetics of carvedilol in healthy dogs. American Journal of Veterinary Research. 61: 57-60. PMID 10630779 DOI: 10.2460/Ajvr.2000.61.57  0.776
1999 Kangarlu A, Burgess RE, Zhu H, Nakayama T, Hamlin RL, Abduljalil AM, Robitaille PM. Cognitive, cardiac, and physiological safety studies in ultra high field magnetic resonance imaging. Magnetic Resonance Imaging. 17: 1407-16. PMID 10609989 DOI: 10.1016/S0730-725X(99)00086-7  0.367
1999 Nakayama T, Nakayama H, Miyamoto M, Hamlin RL. Hemodynamic and electrocardiographic effects of magnesium sulfate in healthy dogs. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 13: 485-90. PMID 10499734 DOI: 10.1111/J.1939-1676.1999.Tb01467.X  0.618
1999 Parameswaran N, Hamlin RL, Nakayama T, Rao SS. Increased splenic capacity in response to transdermal application of nitroglycerine in the dog Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 13: 44-46. PMID 10052063 DOI: 10.1111/J.1939-1676.1999.Tb02164.X  0.371
1998 HAMLIN RL, SCHER AM. Ventricular activation process and genesis of QRS complex in the goat. The American Journal of Physiology. 200: 223-8. PMID 13711032 DOI: 10.1152/Ajplegacy.1961.200.2.223  0.344
1996 HAMLIN RL, SMETZER DL, SMITH CR. ANALYSIS OF QRS COMPLEX RECORDED THROUGH A SEMIORTHOGONAL LEAD SYSTEM IN THE HORSE. The American Journal of Physiology. 207: 325-33. PMID 14205342 DOI: 10.1152/Ajplegacy.1964.207.2.325  0.339
1996 Yamaguchi M, Tangkawattana P, Muto M, Nakade T, Taniyama H, Miyata Y, Nokayama T, Hamlin RL. Myocardial bridge muscle on left anterior descending coronary artery differs from subepicardial myocardium of the left ventricle in dogs Acta Anatomica. 157: 238-247. PMID 9226043 DOI: 10.1159/000147886  0.323
1996 Hamlin RL, Benitz AM, Ericsson GF, Cifelli S, Daurio CP. Effects of enalapril on exercise tolerance and longevity in dogs with heart failure produced by iatrogenic mitral regurgitation Journal of Veterinary Internal Medicine. 10: 85-87. PMID 8683486 DOI: 10.1111/J.1939-1676.1996.Tb02033.X  0.347
1996 Häggström J, Hamlin RL, Hansson K, Kvart C. Heart rate variability in relation to severity of mitral regurgitation in Cavalier King Charles spaniels Journal of Small Animal Practice. 37: 69-75. PMID 8656596  0.303
1993 HAMLIN RL, SALLY JL. Lack of arrhythmogenicity of aminophylline in dogs Journal of Veterinary Pharmacology and Therapeutics. 16: 15-22. PMID 8478996 DOI: 10.1111/J.1365-2885.1993.Tb00284.X  0.343
1993 McKeever KH, Hinchcliff KW, Reed SM, Hamlin RL. Splenectomy alters blood pressure response to incremental treadmill exercise in horses. The American Journal of Physiology. 265: R409-13. PMID 8368396 DOI: 10.1152/Ajpregu.1993.265.2.R409  0.319
1992 Medeiros DM, Liao Z, Hamlin RL. Electrocardiographic Activity and Cardiac Function in Copper-Restricted Rats Proceedings of the Society For Experimental Biology and Medicine. 200: 78-84. PMID 1533287 DOI: 10.3181/00379727-200-43396  0.305
1991 Medeiros DM, Liao Z, Hamlin RL. Copper deficiency in a genetically hypertensive cardiomyopathic rat: Electrocardiogram, functional and ultrastructural aspects Journal of Nutrition. 121: 1026-1034. PMID 2051221 DOI: 10.1093/Jn/121.7.1026  0.333
1991 Hamlin RL. Evidence for or against clinical efficacy of preload reducers Veterinary Clinics of North America - Small Animal Practice. 21: 931-944. PMID 1949500 DOI: 10.1016/S0195-5616(91)50104-2  0.322
1989 Brown CG, Dzwonczyk R, Werman HA, Hamlin RL. Estimating the duration of ventricular fibrillation Annals of Emergency Medicine. 18: 1181-1185. PMID 2817561 DOI: 10.1016/S0196-0644(89)80056-3  0.325
1989 Brown CG, Schlaifer J, Jenkins J, Anstadt GL, Werman HA, Tallman RD, Ashton J, Hamlin RL, Anstadt MP. Effect of direct mechanical ventricular assistance on myocardial hemodynamics during ventricular fibrillation Critical Care Medicine. 17: 1175-1180. PMID 2791596 DOI: 10.1097/00003246-198911000-00015  0.412
1989 Brown CG, Robinson LA, Jenkins J, Bowman K, Schlaifer J, Werman H, Ashton J, Hamlin RL. The effect of norepinephrine versus epinephrine on regional cerebral blood flow during cardiopulmonary resuscitation American Journal of Emergency Medicine. 7: 278-282. PMID 2712889 DOI: 10.1016/0735-6757(89)90169-1  0.3
1989 Billman GE, Hoskins RS, Randall DC, Randall WC, Hamlin RL, Lin YC. Selective vagal postganglionic innervation of the sinoatrial and atrioventricular nodes in the non-human primate Journal of the Autonomic Nervous System. 26: 27-36. PMID 2708782 DOI: 10.1016/0165-1838(89)90104-5  0.35
1989 Robinson LA, Brown CG, Jenkins J, Van Ligten PF, Werman H, Ashton J, Hamlin RL. The effect of norepinephrine versus epinephrine on myocardial hemodynamics during CPR Annals of Emergency Medicine. 18: 336-340. PMID 2705665 DOI: 10.1016/S0196-0644(89)80564-5  0.339
1989 Brown CG, Jenkins J, Werman HA, van Ligten P, Ashton J, Hamlin RL. The effect of UK14,304-18 (an alpha-2 adrenergic agonist) on myocardial blood flow during cardiopulmonary resuscitation Resuscitation. 17: 243-250. PMID 2569755 DOI: 10.1016/0300-9572(89)90040-3  0.341
1988 Brown CG, Taylor RB, Werman HA, Luu T, Spittler G, Hamlin RL. Effect of standard doses of epinephrine on myocardial oxygen delivery and utilization during cardiopulmonary resuscitation. Critical Care Medicine. 16: 536-9. PMID 3359792 DOI: 10.1097/00003246-198805000-00013  0.352
1988 Brown CG, Taylor RB, Werman HA, Luu T, Ashton J, Hamlin RL. Myocardial oxygen delivery/consumption during cardiopulmonary resuscitation: a comparison of epinephrine and phenylephrine. Annals of Emergency Medicine. 17: 302-8. PMID 3354932 DOI: 10.1016/S0196-0644(88)80767-4  0.321
1988 Pettersen JC, Linartz RR, Hamlin RL, Stoll RE. Noninvasive measurement of systemic arterial blood pressure in the conscious beagle dog Toxicological Sciences. 10: 89-97. DOI: 10.1016/0272-0590(88)90254-0  0.332
1987 Brown CG, Werman HA, Davis EA, Hobson J, Hamlin RL. The effects of graded doses of epinephrine on regional myocardial blood flow during cardiopulmonary resuscitation in swine Circulation. 75: 491-497. PMID 3802451 DOI: 10.1161/01.Cir.75.2.491  0.354
1987 Brown CG, Katz SE, Werman HA, Luu T, Davis EA, Hamlin RL. The effect of epinephrine versus methoxamine on regional myocardial blood flow and defibrillation rates following a prolonged cardiorespiratory arrest in a swine model. The American Journal of Emergency Medicine. 5: 362-9. PMID 3620033 DOI: 10.1016/0735-6757(87)90382-2  0.326
1987 Brown CG, Davis EA, Werman HA, Hamlin RL. Methoxamine versus epinephrine on regional cerebral blood flow during cardiopulmonary resuscitation Critical Care Medicine. 15: 682-686. PMID 3595156 DOI: 10.1097/00003246-198707000-00011  0.346
1987 Dorinsky PM, Hamlin RL, Gadek JE. Alterations in regional blood flow during positive end-expiratory pressure ventilation Critical Care Medicine. 15: 106-113. PMID 3542385 DOI: 10.1097/00003246-198702000-00005  0.333
1986 Brown CG, Birinyi F, Werman HA, Davis EA, Hamlin RL. The comparative effects of epinephrine versus phenylephrine on regional cerebral blood flow during carciopulmonary resuscitation Resuscitation. 14: 171-183. PMID 3027811 DOI: 10.1016/0300-9572(86)90122-X  0.306
1985 Dorinsky PM, Hamlin RL, Whitcomb ME, Gadek JE. Hypoxia results in an increase in total systemic shunt flow in dogs Respiration Physiology. 62: 231-243. PMID 4081363 DOI: 10.1016/0034-5687(85)90117-3  0.33
1985 Unverferth DV, Leier CV, Balcerzak SP, Hamlin RL. Usefulness of a free radical scavenger in preventing doxorubicin-induced heart failure in dogs The American Journal of Cardiology. 56: 157-161. PMID 4014022 DOI: 10.1016/0002-9149(85)90585-5  0.359
1984 Crosby HH, Hamlin RL, Strauch SM. Effects of disopyramide on the electrocardiogram and ventricular function in the unanesthetized dog. Journal of Veterinary Pharmacology and Therapeutics. 7: 167-75. PMID 6492243 DOI: 10.1111/J.1365-2885.1984.Tb00896.X  0.395
1984 Unverferth DV, Fertel RH, Thomas J, Leier CV, Croskery R, Hunsaker R, Miller M, Gibb L, Hamlin R. The evolution of beta-adrenergic dysfunction during the induction of canine cobalt cardiomyopathy. Cardiovascular Research. 18: 44-50. PMID 6318998 DOI: 10.1093/Cvr/18.1.44  0.323
1983 Unverferth DV, Mehegan JP, Nelson RW, Scott CC, Leier CV, Hamlin RL. The efficacy of N-acetylcysteine in preventing doxorubicin-induced cardiomyopathy in dogs Seminars in Oncology. 10: 2-6. PMID 6836323 DOI: 10.5555/Uri:Pii:0093775483900581  0.373
1983 Gwathmey JK, Hamlin RL. Protection of turkeys against furazolidone-induced cardiomyopathy The American Journal of Cardiology. 52: 626-628. PMID 6684389 DOI: 10.1016/0002-9149(83)90039-5  0.385
1983 Binkley PF, Bush CA, Kolibash AJ, Magorien RD, Hamlin RL, Leier CV. The anatomic relationship of the esophageal lead to the left atrium. Pacing and Clinical Electrophysiology : Pace. 5: 853-9. PMID 6184687 DOI: 10.1111/J.1540-8159.1982.Tb06567.X  0.362
1982 Hamlin RL, Levesque MJ, Kittleson MD. Intramyocardial pressure and distribution of coronary blood flow during systole and diastole in the horse Cardiovascular Research. 16: 256-262. PMID 7105093 DOI: 10.1093/Cvr/16.5.256  0.331
1977 Ogburn PN, Hamlin RL, Smith CR. Electrocardiographic and vectorcardiographic response to right ventricular hypertrophy in the goat. Journal of Electrocardiology. 10: 215-20. PMID 142123 DOI: 10.1016/S0022-0736(77)80061-7  0.325
1975 Hamlin RL, Burton RR, Leverett SD, Burns JW. Ventricular activation process in minipigs. Journal of Electrocardiology. 8: 113-6. PMID 1151191 DOI: 10.1016/S0022-0736(75)80018-5  0.344
1970 Hamlin RL, Smith CR, Hellerstein HK, Pipers FS. Alterations in QRS during ischemia of the left ventricular free-wall in goats. Journal of Electrocardiology. 2: 223-8. PMID 5367877 DOI: 10.1016/S0022-0736(69)80081-6  0.349
1968 Hamlin RL, Pipers FS, Hellerstein HK, Smith CR. QRS alterations immediately following production of left ventricular free-wall ischemia in dogs. The American Journal of Physiology. 215: 1032-40. PMID 5687494 DOI: 10.1152/Ajplegacy.1968.215.5.1032  0.354
1968 Hamlin RL, Smith CR. CONTRACTILITY OF THE NORMAL CANINE VENTRICLE Annals of the New York Academy of Sciences. 147: 308-317. PMID 4879048 DOI: 10.1111/J.1749-6632.1968.Tb45564.X  0.333
1967 Leighton RF, Hamlin RL, Scarpelli DG, Weissler AM. Drill biopsy of the canine interventricular septum. A new cardiac catheterization technic. The American Journal of Cardiology. 19: 365-71. PMID 6020307 DOI: 10.1016/0002-9149(67)90449-3  0.315
1966 Hamlin RL, Smith CR, Smetzer DL. Sinus arrhythmia in the dog. The American Journal of Physiology. 210: 321-8. PMID 5901470 DOI: 10.1152/Ajplegacy.1966.210.2.321  0.377
1966 Smetzer DL, Smith CR, Hamlin RL. The fourth heart sound in the equine. Annals of the New York Academy of Sciences. 127: 306-21. PMID 5217263 DOI: 10.1111/J.1749-6632.1965.Tb49408.X  0.364
1965 Swamy VC, Hamlin RL, Wolf HH. Influence of myocardial catecholamines on the cardiac action of ouabain. Journal of Pharmaceutical Sciences. 54: 1505-7. PMID 5883226 DOI: 10.1002/Jps.2600541022  0.392
1962 HAMLIN RL, ROBINSON FR, SMITH CR, MARSLAND WP. Heart sounds of healthy Macaca mulatta Journal of Applied Physiology. 17: 199-200. PMID 13904133 DOI: 10.1152/Jappl.1962.17.2.199  0.366
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