| Year |
Citation |
Score |
| 2020 |
Papadopoulos G, Berland R, Sunkavalli A, Coats SR, Darveau RP, Genco CA. Microbial lipid A remodeling controls cross-presentation efficiency and CD8 T cell priming by modulating dendritic cell function. Infection and Immunity. PMID 33257533 DOI: 10.1128/IAI.00335-20 |
0.3 |
|
| 2019 |
Zhu T, McClure R, Harrison OB, Genco C, Massari P. Integrated Bioinformatic Analyses and Immune Characterization of New Vaccine Antigens Expressed during Natural Mucosal Infection. Vaccines. 7. PMID 31627489 DOI: 10.3390/Vaccines7040153 |
0.364 |
|
| 2019 |
Coats SR, Kantrong N, To TT, Jain S, Genco CA, McLean JS, Darveau RP. The distinct immune-stimulatory capacities of strains 381 and ATCC 33277 are determined by the allele and gingipain activity. Infection and Immunity. PMID 31570556 DOI: 10.1128/Iai.00319-19 |
0.389 |
|
| 2019 |
McClure R, Genco CA. Strategies for Global RNA Sequencing of the Human Pathogen Neisseria gonorrhoeae. Methods in Molecular Biology (Clifton, N.J.). 1997: 163-183. PMID 31119624 DOI: 10.1007/978-1-4939-9496-0_11 |
0.318 |
|
| 2019 |
Graves DT, Jiang Y, Genco C. Periodontal disease: bacterial virulence factors, host response and impact on systemic health. Current Opinion in Infectious Diseases. 13: 227-232. PMID 11964791 DOI: 10.1097/00001432-200006000-00005 |
0.377 |
|
| 2018 |
Yost S, Stashenko P, Choi Y, Kukuruzinska M, Genco CA, Salama A, Weinberg EO, Kramer CD, Frias-Lopez J. Increased virulence of the oral microbiome in oral squamous cell carcinoma revealed by metatranscriptome analyses. International Journal of Oral Science. 10: 32. PMID 30420594 DOI: 10.1038/S41368-018-0037-7 |
0.314 |
|
| 2018 |
Ritter JL, Genco CA. -Induced Inflammatory Pyroptosis in Human Macrophages is Dependent on Intracellular Gonococci and Lipooligosaccharide. Journal of Cell Death. 11: 1179066017750902. PMID 29434478 DOI: 10.1177/1179066017750902 |
0.317 |
|
| 2017 |
Moreau MR, Massari P, Genco CA. The Ironclad Truth: How in vivo Transcriptomics and in vitro Mechanistic Studies Shape Our Understanding of Neisseria gonorrhoeae Gene Regulation During Mucosal Infection. Pathogens and Disease. PMID 28520925 DOI: 10.1093/Femspd/Ftx057 |
0.436 |
|
| 2017 |
Kramer CD, Simas AM, He X, Ingalls RR, Weinberg EO, Genco CA. Distinct roles for dietary lipids and Porphyromonas gingivalis infection on atherosclerosis progression and the gut microbiota. Anaerobe. PMID 28442421 DOI: 10.1016/J.Anaerobe.2017.04.011 |
0.41 |
|
| 2017 |
Kramer CD, Genco CA. Microbiota, Immune Subversion, and Chronic Inflammation. Frontiers in Immunology. 8: 255. PMID 28348558 DOI: 10.3389/Fimmu.2017.00255 |
0.447 |
|
| 2016 |
Barth K, Genco CA. Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses. Scientific Reports. 6: 34656. PMID 27698456 DOI: 10.1038/Srep34656 |
0.403 |
|
| 2016 |
Yu C, McClure R, Nudel K, Daou N, Genco CA. Characterization of the Neisseria gonorrhoeae Iron and Fur Regulatory Network. Journal of Bacteriology. PMID 27246574 DOI: 10.1128/Jb.00166-16 |
0.403 |
|
| 2016 |
Stanford EA, Ramirez-Cardenas A, Wang Z, Novikov O, Alamoud K, Koutrakis P, Mizgerd JP, Genco CA, Kukuruzinska M, Monti S, Bais MV, Sherr DH. Role for the Aryl Hydrocarbon Receptor and Diverse Ligands In Oral Squamous Cell Carcinoma Migration and Tumorigenesis. Molecular Cancer Research : McR. PMID 27130942 DOI: 10.1158/1541-7786.Mcr-16-0069 |
0.34 |
|
| 2016 |
Slocum C, Kramer C, Genco CA. Immune dysregulation mediated by the oral microbiome: potential link to chronic inflammation and atherosclerosis Journal of Internal Medicine. 280: 114-128. PMID 26791914 DOI: 10.1111/Joim.12476 |
0.413 |
|
| 2015 |
McClure R, Nudel K, Massari P, Tjaden B, Su X, Rice PA, Genco CA. The Gonococcal Transcriptome during Infection of the Lower Genital Tract in Women. Plos One. 10: e0133982. PMID 26244506 DOI: 10.1371/Journal.Pone.0133982 |
0.423 |
|
| 2015 |
Beaulieu LM, Clancy L, Tanriverdi K, Benjamin EJ, Kramer CD, Weinberg EO, He X, Mekasha S, Mick E, Ingalls RR, Genco CA, Freedman JE. Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans. Plos One. 10: e0131688. PMID 26148065 DOI: 10.1371/Journal.Pone.0131688 |
0.377 |
|
| 2015 |
Nudel K, Massari P, Genco CA. Neisseria gonorrhoeae Modulates Cell Death in Human Endocervical Epithelial Cells through Export of Exosome-Associated cIAP2. Infection and Immunity. 83: 3410-7. PMID 26077759 DOI: 10.1128/Iai.00732-15 |
0.384 |
|
| 2015 |
El-Awady AR, Miles B, Scisci E, Kurago ZB, Palani CD, Arce RM, Waller JL, Genco CA, Slocum C, Manning M, Schoenlein PV, Cutler CW. Porphyromonas gingivalis evasion of autophagy and intracellular killing by human myeloid dendritic cells involves DC-SIGN-TLR2 crosstalk. Plos Pathogens. 10: e1004647. PMID 25679217 DOI: 10.1371/Journal.Ppat.1004647 |
0.385 |
|
| 2015 |
Shaik-Dasthagirisaheb YB, Huang N, Weinberg EO, Shen SS, Genco CA, Gibson FC. Aging and contribution of MyD88 and TRIF to expression of TLR pathway-associated genes following stimulation with Porphyromonas gingivalis Journal of Periodontal Research. 50: 89-102. DOI: 10.1111/Jre.12185 |
0.445 |
|
| 2014 |
Kramer CD, Weinberg EO, Gower AC, He X, Mekasha S, Slocum C, Beaulieu LM, Wetzler L, Alekseyev Y, Gibson FC, Freedman JE, Ingalls RR, Genco CA. Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet. Bmc Genomics. 15: 1176. PMID 25540039 DOI: 10.1186/1471-2164-15-1176 |
0.414 |
|
| 2014 |
McClure R, Tjaden B, Genco C. Identification of sRNAs expressed by the human pathogen Neisseria gonorrhoeae under disparate growth conditions. Frontiers in Microbiology. 5: 456. PMID 25221548 DOI: 10.3389/Fmicb.2014.00456 |
0.357 |
|
| 2014 |
Papadopoulos G, Kramer CD, Slocum CS, Weinberg EO, Hua N, Gudino CV, Hamilton JA, Genco CA. A mouse model for pathogen-induced chronic inflammation at local and systemic sites. Journal of Visualized Experiments : Jove. e51556. PMID 25146644 DOI: 10.3791/51556 |
0.423 |
|
| 2014 |
Slocum C, Coats SR, Hua N, Kramer C, Papadopoulos G, Weinberg EO, Gudino CV, Hamilton JA, Darveau RP, Genco CA. Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation. Plos Pathogens. 10: e1004215. PMID 25010102 DOI: 10.1371/Journal.Ppat.1004215 |
0.481 |
|
| 2014 |
Yu C, Lopez CA, Hu H, Xia Y, Freedman DS, Reddington AP, Daaboul GG, Unlü MS, Genco CA. A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein fur. Plos One. 9: e96832. PMID 24811061 DOI: 10.1371/Journal.Pone.0096832 |
0.37 |
|
| 2014 |
Beaulieu LM, Lin E, Mick E, Koupenova M, Weinberg EO, Kramer CD, Genco CA, Tanriverdi K, Larson MG, Benjamin EJ, Freedman JE. Interleukin 1 receptor 1 and interleukin 1β regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 552-64. PMID 24458711 DOI: 10.1161/Atvbaha.113.302700 |
0.334 |
|
| 2014 |
Slocum C, Genco CA. Bacterial lipid A: The link between infection with a common oral pathogen and atherosclerosis Clinical Lipidology. 9: 599-602. DOI: 10.2217/Clp.14.54 |
0.45 |
|
| 2013 |
Daou N, Yu C, McClure R, Gudino C, Reed GW, Genco CA. Neisseria prophage repressor implicated in gonococcal pathogenesis. Infection and Immunity. 81: 3652-61. PMID 23876804 DOI: 10.1128/Iai.00298-13 |
0.394 |
|
| 2013 |
Miles B, Scisci E, Carrion J, Sabino GJ, Genco CA, Cutler CW. Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen. Journal of Leukocyte Biology. 94: 281-9. PMID 23729500 DOI: 10.1189/Jlb.0213108 |
0.402 |
|
| 2013 |
Papadopoulos G, Weinberg EO, Massari P, Gibson FC, Wetzler LM, Morgan EF, Genco CA. Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss. Journal of Immunology (Baltimore, Md. : 1950). 190: 1148-57. PMID 23264656 DOI: 10.4049/Jimmunol.1202511 |
0.443 |
|
| 2013 |
Barth K, Remick DG, Genco CA. Disruption of immune regulation by microbial pathogens and resulting chronic inflammation Journal of Cellular Physiology. 228: 1413-1422. PMID 23255141 DOI: 10.1002/Jcp.24299 |
0.408 |
|
| 2012 |
Weinberg EO, Genco CA. Directing TRAF-ic: Cell-specific TRAF6 signaling in chronic inflammation and atherosclerosis Circulation. 126: 1678-1680. PMID 23027810 DOI: 10.1161/Circulationaha.112.134379 |
0.444 |
|
| 2012 |
Hayashi C, Papadopoulos G, Gudino CV, Weinberg EO, Barth KR, Madrigal AG, Chen Y, Ning H, LaValley M, Gibson FC, Hamilton JA, Genco CA. Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen. Journal of Immunology (Baltimore, Md. : 1950). 189: 3681-8. PMID 22956579 DOI: 10.4049/Jimmunol.1201541 |
0.796 |
|
| 2012 |
Carrion J, Scisci E, Miles B, Sabino GJ, Zeituni AE, Gu Y, Bear A, Genco CA, Brown DL, Cutler CW. Microbial carriage state of peripheral blood dendritic cells (DCs) in chronic periodontitis influences DC differentiation, atherogenic potential. Journal of Immunology (Baltimore, Md. : 1950). 189: 3178-87. PMID 22891282 DOI: 10.4049/Jimmunol.1201053 |
0.369 |
|
| 2012 |
Yu C, Genco CA. Fur-mediated global regulatory circuits in pathogenic Neisseria species Journal of Bacteriology. 194: 6372-6381. PMID 22885296 DOI: 10.1128/Jb.00262-12 |
0.342 |
|
| 2012 |
Madrigal AG, Barth K, Papadopoulos G, Genco CA. Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells Plos Pathogens. 8. PMID 22685397 DOI: 10.1371/Journal.Ppat.1002723 |
0.798 |
|
| 2012 |
Yua C, Genco CA. Fur-mediated activation of gene transcription in the human pathogen Neisseria gonorrhoeae Journal of Bacteriology. 194: 1730-1742. PMID 22287521 DOI: 10.1128/Jb.06176-11 |
0.373 |
|
| 2011 |
Hayashi C, Viereck J, Hua N, Phinikaridou A, Madrigal AG, Gibson FC, Hamilton JA, Genco CA. Porphyromonas gingivalis accelerates inflammatory atherosclerosis in the innominate artery of ApoE deficient mice. Atherosclerosis. 215: 52-9. PMID 21251656 DOI: 10.1016/J.Atherosclerosis.2010.12.009 |
0.771 |
|
| 2010 |
Hayashi C, Gudino CV, Gibson FC, Genco CA. Review: Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways. Molecular Oral Microbiology. 25: 305-16. PMID 20883220 DOI: 10.1111/J.2041-1014.2010.00582.X |
0.459 |
|
| 2010 |
Hayashi C, Madrigal AG, Liu X, Ukai T, Goswami S, Gudino CV, Gibson FC, Genco CA. Pathogen-mediated inflammatory atherosclerosis is mediated in part via Toll-like receptor 2-induced inflammatory responses. Journal of Innate Immunity. 2: 334-43. PMID 20505314 DOI: 10.1159/000314686 |
0.797 |
|
| 2010 |
Mellin JR, McClure R, Lopez D, Green O, Reinhard B, Genco C. Role of Hfq in iron-dependent and -independent gene regulation in Neisseria meningitidis. Microbiology (Reading, England). 156: 2316-26. PMID 20430815 DOI: 10.1099/Mic.0.039040-0 |
0.779 |
|
| 2010 |
Hayashi C, Gudino CV, Gibson FC, Genco CA. Pathogen-induced inflammation at sites distant from oral infection: Bacterial persistence and induction of cell-specific innate immune inflammatory pathways Molecular Oral Microbiology. 25: 305-316. DOI: 10.1111/j.2041-1014.2010.00582.x |
0.329 |
|
| 2009 |
Follows SA, Murlidharan J, Massari P, Wetzler LM, Genco CA. Neisseria gonorrhoeae infection protects human endocervical epithelial cells from apoptosis via expression of host antiapoptotic proteins. Infection and Immunity. 77: 3602-10. PMID 19546192 DOI: 10.1128/Iai.01366-08 |
0.736 |
|
| 2009 |
Blair P, Rex S, Vitseva O, Beaulieu L, Tanriverdi K, Chakrabarti S, Hayashi C, Genco CA, Iafrati M, Freedman JE. Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. Circulation Research. 104: 346-54. PMID 19106411 DOI: 10.1161/Circresaha.108.185785 |
0.383 |
|
| 2009 |
Hayashi C, Viereck J, Madrigal A, Gibson F, Hamilton J, Genco C. Abstract: P167 PROGRESSION OF PATHOGEN ACCELERATED OCCLUSIVE PLAQUE IN THE INNOMINATE ARTERY OF APOLIPOPROTEIN EDEFICIENT MICE AS DETECTED BY MRI Atherosclerosis Supplements. 10: e484. DOI: 10.1016/S1567-5688(09)70474-X |
0.752 |
|
| 2008 |
Agarwal S, Sebastian S, Szmigielski B, Rice PA, Genco CA. Expression of the gonococcal global regulatory protein Fur and genes encompassing the Fur and iron regulon during in vitro and in vivo infection in women. Journal of Bacteriology. 190: 3129-39. PMID 18310343 DOI: 10.1128/Jb.01830-07 |
0.653 |
|
| 2008 |
Davey M, Liu X, Ukai T, Jain V, Gudino C, Gibson FC, Golenbock D, Visintin A, Genco CA. Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs. Journal of Immunology (Baltimore, Md. : 1950). 180: 2187-95. PMID 18250425 DOI: 10.4049/Jimmunol.180.4.2187 |
0.746 |
|
| 2008 |
Isabella V, Wright LF, Barth K, Spence JM, Grogan S, Genco CA, Clark VL. cis- and trans-acting elements involved in regulation of norB (norZ), the gene encoding nitric oxide reductase in Neisseria gonorrhoeae. Microbiology (Reading, England). 154: 226-39. PMID 18174141 DOI: 10.1099/Mic.0.2007/010470-0 |
0.343 |
|
| 2008 |
Ukai T, Yumoto H, Gibson FC, Genco CA. Macrophage-elicited osteoclastogenesis in response to bacterial stimulation requires toll-like receptor 2-dependent tumor necrosis factor-alpha production Infection and Immunity. 76: 812-819. PMID 17998311 DOI: 10.1128/Iai.01241-07 |
0.431 |
|
| 2008 |
Gibson FC, Ukai T, Genco CA. Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis. Frontiers in Bioscience : a Journal and Virtual Library. 13: 2041-59. PMID 17981690 DOI: 10.2741/2822 |
0.496 |
|
| 2008 |
Liu X, Ukai T, Yumoto H, Davey M, Goswami S, Gibson FC, Genco CA. Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids. Atherosclerosis. 196: 146-54. PMID 17466307 DOI: 10.1016/J.Atherosclerosis.2007.03.025 |
0.733 |
|
| 2007 |
Gibson FC, Genco CA. Porphyromonas gingivalis mediated periodontal disease and atherosclerosis: disparate diseases with commonalities in pathogenesis through TLRs. Current Pharmaceutical Design. 13: 3665-75. PMID 18220804 DOI: 10.2174/138161207783018554 |
0.506 |
|
| 2007 |
Mellin JR, Goswami S, Grogan S, Tjaden B, Genco CA. A novel fur- and iron-regulated small RNA, NrrF, is required for indirect fur-mediated regulation of the sdhA and sdhC genes in Neisseria meningitidis. Journal of Bacteriology. 189: 3686-94. PMID 17351036 DOI: 10.1128/Jb.01890-06 |
0.768 |
|
| 2007 |
Shaik YB, Grogan S, Davey M, Sebastian S, Goswami S, Szmigielski B, Genco CA. Expression of the iron-activated nspA and secY genes in Neisseria meningitidis group B by Fur-dependent and -independent mechanisms. Journal of Bacteriology. 189: 663-9. PMID 17085550 DOI: 10.1128/Jb.01638-06 |
0.763 |
|
| 2006 |
Mydel P, Takahashi Y, Yumoto H, Sztukowska M, Kubica M, Gibson FC, Kurtz DM, Travis J, Collins LV, Nguyen KA, Genco CA, Potempa J. Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection. Plos Pathogens. 2: e76. PMID 16895445 DOI: 10.1371/Journal.Ppat.0020076 |
0.396 |
|
| 2006 |
Al-Qutub MN, Braham PH, Karimi-Naser LM, Liu X, Genco CA, Darveau RP. Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide. Infection and Immunity. 74: 4474-85. PMID 16861633 DOI: 10.1128/Iai.01924-05 |
0.318 |
|
| 2006 |
Bartolini E, Frigimelica E, Giovinazzi S, Galli G, Shaik Y, Genco C, Welsch JA, Granoff DM, Grandi G, Grifantini R. Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection. Molecular Microbiology. 60: 963-72. PMID 16677307 DOI: 10.1111/J.1365-2958.2006.05163.X |
0.366 |
|
| 2006 |
Takahashi Y, Davey M, Yumoto H, Gibson FC, Genco CA. Fimbria-dependent activation of pro-inflammatory molecules in Porphyromonas gingivalis infected human aortic endothelial cells Cellular Microbiology. 8: 738-757. PMID 16611224 DOI: 10.1111/J.1462-5822.2005.00661.X |
0.735 |
|
| 2006 |
Gibson FC, Yumoto H, Takahashi Y, Chou HH, Genco CA. Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis Journal of Dental Research. 85: 106-121. PMID 16434728 DOI: 10.1177/154405910608500202 |
0.359 |
|
| 2006 |
Miyamoto T, Yumoto H, Takahashi Y, Davey M, Gibson FC, Genco CA. Pathogen-accelerated atherosclerosis occurs early after exposure and can be prevented via immunization Infection and Immunity. 74: 1376-1380. PMID 16428788 DOI: 10.1128/Iai.74.2.1376-1380.2006 |
0.749 |
|
| 2005 |
Yumoto H, Chou HH, Takahashi Y, Davey M, Gibson FC, Genco CA. Sensitization of human aortic endothelial cells to lipopolysaccharide via regulation of Toll-like receptor 4 by bacterial fimbria-dependent invasion. Infection and Immunity. 73: 8050-9. PMID 16299299 DOI: 10.1128/Iai.73.12.8050-8059.2005 |
0.759 |
|
| 2005 |
Gibson FC, Savelli J, Van Dyke TE, Genco CA. Gingipain-specific IgG in the sera of patients with periodontal disease is necessary for opsonophagocytosis of Porphyromonas gingivalis Journal of Periodontology. 76: 1629-1636. PMID 16253083 DOI: 10.1902/Jop.2005.76.10.1629 |
0.31 |
|
| 2005 |
Chou HH, Yumoto H, Davey M, Takahashi Y, Miyamoto T, Gibson FC, Genco CA. Porphyromonas gingivalis fimbria-dependent activation of inflammatory genes in human aortic endothelial cells. Infection and Immunity. 73: 5367-78. PMID 16113252 DOI: 10.1128/Iai.73.9.5367-5378.2005 |
0.758 |
|
| 2005 |
Agarwal S, King CA, Klein EK, Soper DE, Rice PA, Wetzler LM, Genco CA. The gonococcal Fur-regulated tbpA and tbpB genes are expressed during natural mucosal gonococcal infection. Infection and Immunity. 73: 4281-7. PMID 15972520 DOI: 10.1128/Iai.73.7.4281-4287.2005 |
0.412 |
|
| 2005 |
Olczak T, Simpson W, Liu X, Genco CA. Iron and heme utilization in Porphyromonas gingivalis. Fems Microbiology Reviews. 29: 119-44. PMID 15652979 DOI: 10.1016/J.Femsre.2004.09.001 |
0.395 |
|
| 2004 |
Liu X, Sroka A, Potempa J, Genco CA. Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR. Biological Chemistry. 385: 1049-57. PMID 15576325 DOI: 10.1515/Bc.2004.136 |
0.384 |
|
| 2004 |
Sztukowska M, Sroka A, Bugno M, Banbula A, Takahashi Y, Pike RN, Genco CA, Travis J, Potempa J. The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities. Molecular Microbiology. 54: 1393-408. PMID 15554977 DOI: 10.1111/J.1365-2958.2004.04357.X |
0.32 |
|
| 2004 |
Grifantini R, Frigimelica E, Delany I, Bartolini E, Giovinazzi S, Balloni S, Agarwal S, Galli G, Genco C, Grandi G. Characterization of a novel Neisseria meningitidis Fur and iron-regulated operon required for protection from oxidative stress: utility of DNA microarray in the assignment of the biological role of hypothetical genes. Molecular Microbiology. 54: 962-79. PMID 15522080 DOI: 10.1111/J.1365-2958.2004.04315.X |
0.416 |
|
| 2004 |
Gibson FC, Hong C, Chou HH, Yumoto H, Chen J, Lien E, Wong J, Genco CA. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice Circulation. 109: 2801-2806. PMID 15123526 DOI: 10.1161/01.Cir.0000129769.17895.F0 |
0.425 |
|
| 2004 |
Simpson W, Olczak T, Genco CA. Lysine-specific gingipain K and heme/hemoglobin receptor HmuR are involved in heme utilization in Porphyromonas gingivalis. Acta Biochimica Polonica. 51: 253-62. PMID 15094847 DOI: 10.18388/Abp.2004_3618 |
0.364 |
|
| 2004 |
Gibson FC, Gonzalez DA, Wong J, Genco CA. Porphyromonas gingivalis-specific immunoglobulin G prevents P. gingivalis-elicited oral bone loss in a murine model. Infection and Immunity. 72: 2408-11. PMID 15039370 DOI: 10.1128/Iai.72.4.2408-2411.2004 |
0.333 |
|
| 2003 |
Gyurko R, Boustany G, Huang PL, Kantarci A, Van Dyke TE, Genco CA, Gibson FC. Mice lacking inducible nitric oxide synthase demonstrate impaired killing of Porphyromonas gingivalis. Infection and Immunity. 71: 4917-24. PMID 12933833 DOI: 10.1128/Iai.71.9.4917-4924.2003 |
0.372 |
|
| 2003 |
Grifantini R, Sebastian S, Frigimelica E, Draghi M, Bartolini E, Muzzi A, Rappuoli R, Grandi G, Genco CA. Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B. Proceedings of the National Academy of Sciences of the United States of America. 100: 9542-7. PMID 12883001 DOI: 10.1073/Pnas.1033001100 |
0.636 |
|
| 2003 |
Gonzalez D, Tzianabos AO, Genco CA, Gibson FC. Immunization with Porphyromonas gingivalis capsular polysaccharide prevents P. gingivalis-elicited oral bone loss in a murine model. Infection and Immunity. 71: 2283-7. PMID 12654858 DOI: 10.1128/Iai.71.4.2283-2287.2003 |
0.354 |
|
| 2003 |
Genco CA, Maloy WL, Kari UP, Motley M. Antimicrobial activity of magainin analogues against anaerobic oral pathogens International Journal of Antimicrobial Agents. 21: 75-78. PMID 12507842 DOI: 10.1016/S0924-8579(02)00275-3 |
0.311 |
|
| 2002 |
Niederman R, Kelderman H, Socransky S, Ostroff G, Genco C, Kent R, Stashenko P. Enhanced neutrophil emigration and Porphyromonas gingivalis reduction following PGG-glucan treatment of mice. Archives of Oral Biology. 47: 613-8. PMID 12221019 DOI: 10.1016/S0003-9969(02)00042-0 |
0.409 |
|
| 2002 |
Sebastian S, Agarwal S, Murphy JR, Genco CA. The gonococcal fur regulon: identification of additional genes involved in major catabolic, recombination, and secretory pathways. Journal of Bacteriology. 184: 3965-74. PMID 12081969 DOI: 10.1128/Jb.184.14.3965-3974.2002 |
0.593 |
|
| 2002 |
Nassar H, Chou HH, Khlgatian M, Gibson FC, Van Dyke TE, Genco CA. Role for fimbriae and lysine-specific cysteine proteinase gingipain K in expression of interleukin-8 and monocyte chemoattractant protein in Porphyromonas gingivalis-infected endothelial cells Infection and Immunity. 70: 268-276. PMID 11748192 DOI: 10.1128/Iai.70.1.268-276.2002 |
0.422 |
|
| 2002 |
Khlgatian M, Nassar H, Chou HH, Gibson FC, Genco CA. Fimbria-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis-infected endothelial cells Infection and Immunity. 70: 257-267. PMID 11748191 DOI: 10.1128/Iai.70.1.257-267.2002 |
0.412 |
|
| 2001 |
Gibson FC, Genco CA. Prevention of Porphyromonas gingivalis-induced oral bone loss following immunization with gingipain R1 Infection and Immunity. 69: 7959-7963. PMID 11705986 DOI: 10.1128/Iai.69.12.7959-7963.2001 |
0.374 |
|
| 2001 |
Sroka A, Sztukowska M, Potempa J, Travis J, Genco CA. Degradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis. Journal of Bacteriology. 183: 5609-16. PMID 11544223 DOI: 10.1128/Jb.183.19.5609-5616.2001 |
0.331 |
|
| 2001 |
Olczak T, Dixon DW, Genco CA. Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrins. Journal of Bacteriology. 183: 5599-608. PMID 11544222 DOI: 10.1128/Jb.183.19.5599-5608.2001 |
0.306 |
|
| 2001 |
Fichorova RN, Desai PJ, Gibson FC, Genco CA. Distinct proinflammatory host responses to Neisseria gonorrhoeae infection in immortalized human cervical and vaginal epithelial cells Infection and Immunity. 69: 5840-5848. PMID 11500462 DOI: 10.1128/Iai.69.9.5840-5848.2001 |
0.345 |
|
| 2001 |
Genco CA, Dixon DW. Emerging strategies in microbial haem capture. Molecular Microbiology. 39: 1-11. PMID 11123683 DOI: 10.1046/J.1365-2958.2001.02231.X |
0.343 |
|
| 2000 |
Simpson W, Olczak T, Genco CA. Characterization and expression of HmuR, a TonB-dependent hemoglobin receptor of Porphyromonas gingivalis Journal of Bacteriology. 182: 5737-5748. PMID 11004172 DOI: 10.1128/Jb.182.20.5737-5748.2000 |
0.416 |
|
| 2000 |
Desai PJ, Garges E, Genco CA. Pathogenic neisseriae can use hemoglobin, transferrin, and lactoferrin independently of the tonB locus Journal of Bacteriology. 182: 5586-5591. PMID 10986265 DOI: 10.1128/Jb.182.19.5586-5591.2000 |
0.317 |
|
| 1999 |
Simpson W, Wang CY, Mikolajczyk-Pawlinska J, Potempa J, Travis J, Bond VC, Genco CA. Transposition of the endogenous insertion sequence element IS1126 modulates gingipain expression in Porphyromonas gingivalis. Infection and Immunity. 67: 5012-20. PMID 10496872 DOI: 10.1128/Iai.67.10.5012-5020.1999 |
0.378 |
|
| 1999 |
Deshpande RG, Khan M, Genco CA. Invasion strategies of the oral pathogen Porphyromonas gingivalis: Implications for cardiovascular disease Invasion and Metastasis. 18: 57-69. PMID 10364686 DOI: 10.1159/000024499 |
0.414 |
|
| 1999 |
Sebastian S, Genco CA. FbpC is not essential for iron acquisition in Neisseria gonorrhoeae. Infection and Immunity. 67: 3141-5. PMID 10338533 DOI: 10.1128/Iai.67.6.3141-3145.1999 |
0.602 |
|
| 1999 |
Genco CA, Potempa J, Mikolajczyk-Pawlinska J, Travis J. Role of gingipains R in the pathogenesis of Porphyromonas gingivalis-mediated periodontal disease. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 28: 456-65. PMID 10194062 DOI: 10.1086/515156 |
0.372 |
|
| 1998 |
Genco CA, Van Dyke T, Amar S. Animal models for Porphyromonas gingivalis-mediated periodontal disease Trends in Microbiology. 6: 444-449. PMID 9846362 DOI: 10.1016/S0966-842X(98)01363-8 |
0.349 |
|
| 1998 |
Deshpande RG, Khan MB, Genco CA. Invasion of aortic and heart endothelial cells by Porphyromonas gingivalis Infection and Immunity. 66: 5337-5343. PMID 9784541 DOI: 10.1128/Iai.66.11.5337-5343.1998 |
0.388 |
|
| 1998 |
Genco CA, Odusanya BM, Potempa J, Mikolajczyk-Pawlinska J, Travis J. A peptide domain on gingipain R which confers immunity against Porphyromonas gingivalis infection in mice. Infection and Immunity. 66: 4108-14. PMID 9712755 DOI: 10.1128/Iai.66.9.4108-4114.1998 |
0.302 |
|
| 1997 |
Forng RY, Ekechukwu CR, Subbarao S, Morse SA, Genco CA. Promoter mapping and transcriptional regulation of the iron-regulated Neisseria gonorrhoeae fbpA gene. Journal of Bacteriology. 179: 3047-52. PMID 9139927 DOI: 10.1128/Jb.179.9.3047-3052.1997 |
0.342 |
|
| 1997 |
Njoroge T, Genco RJ, Sojar HT, Hamada N, Genco CA. A role for fimbriae in Porphyromonas gingivalis invasion of oral epithelial cells Infection and Immunity. 65: 1980-1984. PMID 9125593 DOI: 10.1128/Iai.65.5.1980-1984.1997 |
0.366 |
|
| 1996 |
Desai PJ, Angerer A, Genco CA. Analysis of Fur binding to operator sequences within the Neisseria gonorrhoeae fbpA promoter Journal of Bacteriology. 178: 5020-5023. PMID 8759870 DOI: 10.1128/Jb.178.16.5020-5023.1996 |
0.322 |
|
| 1996 |
Genco CA, Desai PJ. Iron acquisition in the pathogenic Neisseria Trends in Microbiology. 4: 179-184. PMID 8727597 DOI: 10.1016/0966-842X(96)10029-9 |
0.341 |
|
| 1996 |
Cutler CW, Eke PI, Genco CA, Van Dyke TE, Arnold RR. Hemin-induced modifications of the antigenicity and hemin-binding capacity of Porphyromonas gingivalis lipopolysaccharide Infection and Immunity. 64: 2282-2287. PMID 8675338 DOI: 10.1128/Iai.64.6.2282-2287.1996 |
0.311 |
|
| 1995 |
Genco CA, Schifferle RE, Njoroge T, Forng RY, Cutler CW. Resistance of a Tn4351-generated polysaccharide mutant of Porphyromonas gingivalis to polymorphonuclear leukocyte killing Infection and Immunity. 63: 393-401. PMID 7822002 DOI: 10.1128/Iai.63.2.393-401.1995 |
0.309 |
|
| 1995 |
Genco CA, Simpson W, Forng RY, Egal M, Odusanya BM. Characterization of a TN4351-generated heroin uptake mutant of porphyromonas gingivalis: Evidence for the coordinate regulation of virulence factors by hemin Infection and Immunity. 63: 2459-2466. PMID 7790057 DOI: 10.1128/Iai.63.7.2459-2466.1995 |
0.366 |
|
| 1995 |
Cutler CW, Kalmar JR, Genco CA. Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalis Trends in Microbiology. 3: 45-51. PMID 7728384 DOI: 10.1016/S0966-842X(00)88874-5 |
0.345 |
|
| 1995 |
Genco CA. Regulation of hemin and iron transport in Porphyromonas gingivalis Advances in Dental Research. 9: 41-47. PMID 7669213 DOI: 10.1177/08959374950090010801 |
0.42 |
|
| 1995 |
Desai PJ, Nzeribe R, Genco CA. Binding and accumulation of hemin in Neisseria gonorrhoeae Infection and Immunity. 63: 4634-4641. PMID 7591117 DOI: 10.1128/Iai.63.12.4634-4641.1995 |
0.314 |
|
| 1994 |
Genco CA, Berish SA, Cheng-Yen Chen, Morse S, Trees DL. Genetic diversity of the iron-binding protein (Fbp) gene of the pathogenic and commensal Neisseria Fems Microbiology Letters. 116: 123-129. PMID 8150256 DOI: 10.1111/J.1574-6968.1994.Tb06690.X |
0.318 |
|
| 1994 |
Genco CA, Odusanya BM, Brown G. Binding and accumulation of hemin in Porphyromonas gingivalis are induced by hemin Infection and Immunity. 62: 2885-2892. PMID 8005678 DOI: 10.1128/Iai.62.7.2885-2892.1994 |
0.356 |
|
| 1992 |
Genco CA, Kapczynski DR, Cutler CW, Arko RJ, Arnold RR. Influence of immunization on Porphyromonas gingivalis colonization and invasion in the mouse chamber model Infection and Immunity. 60: 1447-1454. PMID 1312515 DOI: 10.1128/Iai.60.4.1447-1454.1992 |
0.374 |
|
| 1991 |
Genco CA, Cutler CW, Kapczynski D, Maloney K, Arnold RR. A novel mouse model to study the virulence of and host response to Porphyromonas (Bacteroides) gingivalis Infection and Immunity. 59: 1255-1263. PMID 2004807 DOI: 10.1128/Iai.59.4.1255-1263.1991 |
0.366 |
|
| 1991 |
Genco CA, Chen CY, Arko RJ, Kapczynski DR, Morse SA. Isolation and characterization of a mutant of Neisseria gonorrhoeae that is defective in the uptake of iron from transferrin and haemoglobin and is avirulent in mouse subcutaneous chambers. Journal of General Microbiology. 137: 1313-21. PMID 1919507 DOI: 10.1099/00221287-137-6-1313 |
0.32 |
|
| 1990 |
Berish SA, Mietzner TA, Mayer LW, Genco CA, Holloway BP, Morse SA. Molecular cloning and characterization of the structural gene for the major iron-regulated protein expressed by Neisseria gonorrhoeae Journal of Experimental Medicine. 171: 1535-1546. PMID 2110241 DOI: 10.1084/Jem.171.5.1535 |
0.311 |
|
| 1989 |
Chen CY, Genco CA, Rock JP, Morse SA. Physiology and metabolism of Neisseria gonorrhoeae and Neisseria meningitidis: Implications for pathogenesis Clinical Microbiology Reviews. 2. PMID 2497961 DOI: 10.1128/Cmr.2.Suppl.S35 |
0.324 |
|
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