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Elisabeth D. Martinez, Ph.D. - Publications

Affiliations: 
2002 Georgetown University Medical Center, Washington, DC, United States 
Area:
Molecular Biology, Biochemistry, Oncology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Matthews KA, Senagbe KM, Notzel C, Gonzalez CA, Tong X, Rijo-Ferreira F, Natarajan BV, Miguel-Blanco C, Lafuente-Monasterio MJ, Garcia BA, Kafsack BF, Martinez ED. Disruption of the Plasmodium falciparum life cycle through transcriptional reprogramming by inhibitors of Jumonji demethylases. Acs Infectious Diseases. PMID 32272012 DOI: 10.1021/Acsinfecdis.9B00455  0.328
2019 Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, et al. Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes. Journal of Cell Science. PMID 31515279 DOI: 10.1242/Jcs.231514  0.313
2018 Zhang QJ, Tran TAT, Wang M, Ranek MJ, Kokkonen-Simon KM, Gao J, Luo X, Tan W, Kyrychenko V, Liao L, Xu J, Hill JA, Olson EN, Kass DA, Martinez ED, et al. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nature Communications. 9: 5230. PMID 30531796 DOI: 10.1038/S41467-018-07173-2  0.32
2018 Bayo J, Tran TA, Wang L, Peña-Llopis S, Das AK, Martinez ED. Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks. Cell Reports. 25: 1040-1050.e5. PMID 30355483 DOI: 10.1016/J.Celrep.2018.09.081  0.307
2018 Mender I, LaRanger R, Luitel K, Peyton M, Girard L, Lai TP, Batten K, Cornelius C, Dalvi MP, Ramirez M, Du W, Wu LF, Altschuler SJ, Brekken R, Martinez ED, et al. Telomerase-Mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance. Neoplasia (New York, N.Y.). 20: 826-837. PMID 30015158 DOI: 10.1016/J.Neo.2018.06.002  0.311
2017 Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, ... ... Martinez ED, et al. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors. Cell Reports. 19: 1669-1684. PMID 28538184 DOI: 10.1016/J.Celrep.2017.04.077  0.329
2017 Hatch SB, Yapp C, Montenegro RC, Savitsky P, Gamble V, Tumber A, Ruda GF, Bavetsias V, Fedorov O, Atrash B, Raynaud F, Lanigan R, Carmichael L, Tomlin K, Burke R, ... ... Martinez ED, et al. Assessing histone demethylase inhibitors in cells: lessons learned. Epigenetics & Chromatin. 10: 9. PMID 28265301 DOI: 10.1186/S13072-017-0116-6  0.357
2016 Peña-Llopis S, Wan Y, Martinez ED. Unique epigenetic gene profiles define human breast cancers with poor prognosis. Oncotarget. PMID 27863398 DOI: 10.18632/Oncotarget.13334  0.31
2015 Wang L, Kofler M, Brosch G, Melesina J, Sippl W, Martinez ED, Easmon J. 2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity. Plos One. 10: e0134556. PMID 26698121 DOI: 10.1371/Journal.Pone.0134556  0.32
2015 Trošt N, Peña-Llopis S, Koirala S, Stojan J, Potts PR, Tacer KF, Martinez ED. γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers. Oncotarget. PMID 26556877 DOI: 10.18632/Oncotarget.6006  0.334
2015 Bayo J, Dalvi MP, Martinez ED. Successful strategies in the discovery of small-molecule epigenetic modulators with anticancer potential. Future Medicinal Chemistry. PMID 26510529 DOI: 10.4155/Fmc.15.140  0.323
2015 Duan L, Rai G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chemistry & Biology. PMID 26364928 DOI: 10.1016/J.Chembiol.2015.08.007  0.392
2015 Thinnes CC, Tumber A, Yapp C, Scozzafava G, Yeh T, Chan MC, Tran TA, Hsu K, Tarhonskaya H, Walport LJ, Wilkins SE, Martinez ED, Müller S, Pugh CW, Ratcliffe PJ, et al. Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chemical Communications (Cambridge, England). 51: 15458-61. PMID 26345662 DOI: 10.1039/C5Cc06095H  0.306
2015 Schneider P, Miguel Bayo-Fina J, Singh R, Kumar Dhanyamraju P, Holz P, Baier A, Fendrich V, Ramaswamy A, Baumeister S, Martinez ED, Lauth M. Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1. Nature Communications. 6: 8023. PMID 26310823 DOI: 10.1038/Ncomms9023  0.321
2015 Huffman KE, Carstens R, Martinez ED. A Subset of Nuclear Receptors are Uniquely Expressed in Uveal Melanoma Cells. Frontiers in Endocrinology. 6: 93. PMID 26217306 DOI: 10.3389/Fendo.2015.00093  0.39
2014 Tran TA, Wichterman-Kouznetsova J, Varghese D, Huang R, Huang W, Becker M, Austin CP, Inglese J, Johnson RL, Martinez ED. Identification of small molecule modulators of gene transcription with anticancer activity. Acs Chemical Biology. 9: 2603-11. PMID 25188650 DOI: 10.1021/Cb500532X  0.413
2013 Huffman K, Martinez ED. Pre-clinical studies of epigenetic therapies targeting histone modifiers in lung cancer. Frontiers in Oncology. 3: 235. PMID 24058902 DOI: 10.3389/Fonc.2013.00235  0.333
2013 Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, ... ... Martinez ED, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nature Communications. 4: 2035. PMID 23792809 DOI: 10.1038/Ncomms3035  0.378
2013 Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Penã-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, ... ... Martinez ED, et al. Erratum: A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth Nature Communications. 4. DOI: 10.1038/Ncomms3639  0.318
2012 Chang J, Varghese DS, Gillam MC, Peyton M, Modi B, Schiltz RL, Girard L, Martinez ED. Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide. British Journal of Cancer. 106: 116-25. PMID 22158273 DOI: 10.1038/Bjc.2011.532  0.344
2011 Best AM, Chang J, Dull AB, Beutler JA, Martinez ED. Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay. Journal of Biomedicine & Biotechnology. 2011: 868095. PMID 21234371 DOI: 10.1155/2011/868095  0.389
2010 Holbeck S, Chang J, Best AM, Bookout AL, Mangelsdorf DJ, Martinez ED. Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions. Molecular Endocrinology (Baltimore, Md.). 24: 1287-96. PMID 20375240 DOI: 10.1210/Me.2010-0040  0.44
2008 Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression. Analytical Biochemistry. 375: 237-48. PMID 18211814 DOI: 10.1016/J.Ab.2007.12.028  0.391
2006 Martinez ED, Hager GL. Development of assays for nuclear receptor modulators using fluorescently tagged proteins. Methods in Enzymology. 414: 37-50. PMID 17110185 DOI: 10.1016/S0076-6879(06)14003-3  0.442
2006 Martinez ED, Dull AB, Beutler JA, Hager GL. High-content fluorescence-based screening for epigenetic modulators. Methods in Enzymology. 414: 21-36. PMID 17110184 DOI: 10.1016/S0076-6879(06)14002-1  0.358
2006 Qiu Y, Zhao Y, Becker M, John S, Parekh BS, Huang S, Hendarwanto A, Martinez ED, Chen Y, Lu H, Adkins NL, Stavreva DA, Wiench M, Georgel PT, Schiltz RL, et al. HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription. Molecular Cell. 22: 669-79. PMID 16762839 DOI: 10.1016/J.Molcel.2006.04.019  0.404
2005 Martinez ED, Rayasam GV, Dull AB, Walker DA, Hager GL. An estrogen receptor chimera senses ligands by nuclear translocation. The Journal of Steroid Biochemistry and Molecular Biology. 97: 307-21. PMID 16162406 DOI: 10.1016/J.Jsbmb.2005.06.033  0.423
2005 Martinez ED, Pattabiraman N, Danielsen M. Analysis of the hormone-binding domain of steroid receptors using chimeras generated by homologous recombination. Experimental Cell Research. 308: 320-33. PMID 15936754 DOI: 10.1016/J.Yexcr.2005.03.040  0.62
2004 Nagaich AK, Rayasam GV, Martinez ED, Becker M, Qiu Y, Johnson TA, Elbi C, Fletcher TM, John S, Hager GL. Subnuclear trafficking and gene targeting by steroid receptors. Annals of the New York Academy of Sciences. 1024: 213-20. PMID 15265783 DOI: 10.1196/Annals.1321.002  0.447
2003 Tirado OM, Martinez ED, Rodriguez OC, Danielsen M, Selva DM, Reventós J, Munell F, Suárez-Quian CA. Methoxyacetic acid disregulation of androgen receptor and androgen-binding protein expression in adult rat testis. Biology of Reproduction. 68: 1437-46. PMID 12606434 DOI: 10.1095/Biolreprod.102.004937  0.665
2002 Martinez ED, Danielsen M. Loss of androgen receptor transcriptional activity at the G(1)/S transition. The Journal of Biological Chemistry. 277: 29719-29. PMID 12055183 DOI: 10.1074/Jbc.M112134200  0.642
2000 List HJ, Smith CL, Martinez E, Harris VK, Danielsen M, Riegel AT. Effects of antiandrogens on chromatin remodeling and transcription of the integrated mouse mammary tumor virus promoter Experimental Cell Research. 260: 160-165. PMID 11010820 DOI: 10.1006/Excr.2000.5018  0.626
1998 Martinez E, Moore DD, Keller E, Pearce D, Heuvel JPV, Robinson V, Gottlieb B, MacDonald PN, Simons SS, Sanchez E, Danielsen M. The Nuclear Receptor Resource: a growing family. Nucleic Acids Research. 26: 239-241. PMID 9471621 DOI: 10.1093/Nar/26.1.239  0.606
1997 Martinez E, Moore DD, Keller E, Pearce D, Robinson V, MacDonald PN, Simons SS, Sanchez E, Danielsen M. The Nuclear Receptor Resource Project. Nucleic Acids Research. 25: 163-5. PMID 9016529 DOI: 10.1093/Nar/25.1.163  0.613
1996 Danielsen M, Martinez E. The Glucocorticoid Receptor Resource Nucleic Acids Research. 24: 155-156. PMID 8594567 DOI: 10.1093/Nar/24.1.155  0.629
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